Transfer frame for transferring X-ray powder diffraction sample plate
By designing a transfer rack with closed doors and multi-sample storage chambers, the leakage and contamination of X-ray powder diffraction samples during the transfer process is solved, safe and efficient sample transfer is achieved, and experimental efficiency and accuracy are improved.
Patent Information
- Application Number
- CN202420017744.3
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-01-04
- Publication Date
- 2024-12-27
- Estimated Expiration
- 2034-01-04
AI Technical Summary
During the transfer of X-ray powder diffraction sample, solid powder is prone to leak, resulting in health hazards and environmental pollution of the experimenter. At the same time, external impurities enter the sample, affecting the accuracy of the experimental results. The protective measures increase the operating cost and time and reduce the Experimental efficiency.
A transfer rack for transferring X-ray powder diffraction sample plate is designed, including a base and a transfer rack main body. Multiple sample plate accommodating chambers and closed doors are provided in the main body. The closed door is tightened by magnets to prevent powder leakage and impurities. Enter and increase the sample plate capacity through multiple cross plates to achieve rapid transfer.
It effectively prevents sample powder from drifting and external impurities from being doped, ensures the health and environmental safety of the experimenter, and improves the transfer efficiency and the accuracy of experimental results.
Smart Images
Figure CN222240358U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the field of drug crystallization equipment, in particular to a transfer rack for transferring X-ray powder diffraction sample plates. Background Art
[0002] X-ray powder diffraction (XRPD) is the main method for studying drug crystal forms. After X-ray irradiation, the atoms inside the compound itself scatter, and there is a certain interference between the scattered waves to produce a combined diffraction wave. By collecting information such as diffraction peak position, diffraction peak linearity, and diffraction peak intensity, the corresponding crystal structure can be obtained by analyzing the results. X-ray diffraction research runs through all stages of drug quality control, such as raw material research and formulation research. It can be used for drug qualitative analysis, drug quantitative analysis, crystallinity testing, etc. It has the advantages of specificity, accuracy, speed, and simple pretreatment, and is widely included in pharmacopoeias of various countries. For example, Part IV 0451 of the 2020 edition of the Chinese Pharmacopoeia specifically explains the application of X-ray diffraction in drug research, and 9015 specifies the guiding principles for drug crystal form research and crystal form quality control.
[0003] In order to avoid harm to experimenters caused by toxic and harmful compounds, the sample preparation process of XRPD is carried out in a fume hood: the powder sample is evenly spread on the silicon wafer, and then transferred to the X-ray diffractometer (Burker D8 Advance) for testing. During the sample transfer process, the solid powder is exposed to the environment. On the one hand, the exposed solid powder leaves the fume hood, which will create potential risks, harm the health of experimenters, and cause a certain degree of pollution to the experimental environment; on the other hand, during the transfer process, impurities in the environment are also easily mixed into the solid powder to be tested, causing contamination to the sample, thereby affecting the accuracy of the experimental results. However, if the solid powder is to be ensured not to be exposed to the environment, the operating cost and time cost of the operator transferring the silicon wafer will increase, thereby affecting the overall efficiency of the experiment.
[0004] Therefore, there is a need in the art for a transfer rack for transferring X-ray powder diffraction sample plates that can prevent leakage of solid powder to be tested, prevent environmental impurities from entering the sample, help protect the health of experimenters and the safety of the experimental environment, and improve the transfer efficiency. Utility Model Content
[0005] In order to solve the above technical problems, the utility model provides the following technical solutions:
[0006] A transfer rack for transferring X-ray powder diffraction sample plates, the transfer rack for transferring X-ray powder diffraction sample plates comprising a base and a transfer rack body, the transfer rack body being fixedly mounted on the top of the base, a plurality of sample plate accommodating cavities being arranged in the transfer rack body, the plurality of sample plate accommodating cavities being arranged longitudinally, the sample plate accommodating cavities being used for placing the X-ray powder diffraction sample plates to be transferred, a closed door being provided on one side of the transfer rack body, the closed door being used for completely closing the transfer rack body.
[0007] Specifically, the transfer rack body is a rectangular parallelepiped, the bottom surface of the transfer rack body coincides with the top surface of the base, the interior of the transfer rack body is a cavity, and a plurality of parallel horizontal plates are fixedly installed in the cavity. The plurality of horizontal plates are arranged longitudinally to divide the cavity into a plurality of sample plate accommodating cavities, and each sample plate accommodating cavity can hold an X-ray powder diffraction sample plate.
[0008] Specifically, a recessed portion is provided on one side of the horizontal plate close to the closed door, and the recessed portion is U-shaped, which facilitates operators to remove the X-ray powder diffraction sample plate.
[0009] Specifically, a hinge is fixedly installed on one side of the closed door, and the closed door is rotatably installed on one side of the transfer frame body through the hinge.
[0010] Specifically, a groove is provided on the inner side of the top end of the transfer rack body, a groove is provided on the top of the base, and the closed door is slidably installed on one side of the transfer rack body through the groove.
[0011] Specifically, a first magnet is arranged on the side where the closed door contacts the transfer rack body, and a second magnet is also arranged on the side where the transfer rack body contacts the closed door. The first magnet and the second magnet attract each other to fasten the closed door to one side of the transfer rack body.
[0012] Specifically, the number of the sample plate accommodating cavities is 3-16.
[0013] Specifically, the height of the transfer rack body is 30-40 cm, the length of the transfer rack body is 6-8 cm, and the width of the transfer rack body is 6-8 cm.
[0014] Specifically, the height of the base is 0.5-1.5 cm, the length of the base is 10-12 cm, and the width of the base is 10-12 cm.
[0015] Specifically, a silicone gasket is provided at the bottom of the base.
[0016] The beneficial effects of the utility model include:
[0017] 1. The transfer rack for transferring X-ray powder diffraction sample plates provided by the utility model can effectively prevent the sample powder from scattering and leaking during the transfer process by setting a closed door, and can also isolate external impurities from entering the interior of the sample powder, which can ensure the health of the experimenters and the accuracy of the detection.
[0018] 2. The transfer rack for transferring X-ray powder diffraction sample plates provided by the utility model divides the transfer rack body into multiple sample plate accommodating cavities through the arrangement of multiple horizontal plates, and can store multiple X-ray powder diffraction sample plates at the same time. The operator can complete the transfer of multiple sample plates at one time, thereby improving the throughput of a single transfer. BRIEF DESCRIPTION OF THE DRAWINGS
[0019] Figure 1 A schematic diagram of the structure of a transfer rack for transferring an X-ray powder diffraction sample plate provided by the utility model;
[0020] Figure 2 A side view of a transfer rack for transferring an X-ray powder diffraction sample plate provided by the utility model;
[0021] Figure 3 A top view of a transfer rack for transferring X-ray powder diffraction sample plates provided by the utility model.
[0022] In the figure, 1, base; 2, transfer rack body; 3, sample plate accommodating cavity; 4, closed door; 5, horizontal plate; 6, recessed portion; 7, first magnet; 8, second magnet. DETAILED DESCRIPTION
[0023] The technical solution of the utility model will be described clearly and completely below. Obviously, the described embodiments are part of the embodiments of the utility model, not all of them. Based on the embodiments of the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.
[0024] Embodiment 1
[0025] like Figure 1-3As shown, this embodiment shows an external overall structural schematic diagram, a side view and a top view of a transfer rack for transferring X-ray powder diffraction sample plates. The transfer rack for transferring X-ray powder diffraction sample plates includes a base 1 and a transfer rack body 2. The transfer rack body 2 is fixedly installed on the top of the base 1. The transfer rack body 2 and the base 1 are integrally formed. 16 sample plate accommodating cavities 3 are arranged in the transfer rack body 2. The 16 sample plate accommodating cavities 3 are arranged longitudinally. The sample plate accommodating cavities 3 are used to place the X-ray powder diffraction sample plates to be transferred. A closed door 4 is provided on one side of the transfer rack body 2. A hinge is fixedly installed on one side of the closed door 4. The closed door 4 is rotatably installed on one side of the transfer rack body 2 by the hinge. The closed door 4 is used to completely close the transfer rack body 2.
[0026] A silicone gasket is provided at the bottom of the base 1. The silicone gasket has an anti-slip effect, improves the stability of the base 1, and effectively prevents the operator from accidentally touching it and causing the transfer rack to tip over.
[0027] The transfer rack body 2 is a rectangular parallelepiped, the bottom surface of the transfer rack body 2 coincides with the top surface of the base 1, the interior of the transfer rack body 2 is a cavity, and 15 parallel horizontal plates 5 are fixedly installed in the cavity. The 15 horizontal plates 5 are arranged longitudinally to divide the cavity into 16 sample plate accommodating cavities 3, and each sample plate accommodating cavity 3 can hold an X-ray powder diffraction sample plate.
[0028] A recessed portion 6 is provided on one side of the horizontal plate 5 close to the closed door 4. The recessed portion 6 is U-shaped and reserves space for the operator's hand movements, making it convenient for the operator to remove the X-ray powder diffraction sample plate.
[0029] A first magnet 7 is arranged on the side where the closed door 4 contacts the transfer rack body 2, and a second magnet 8 is also arranged on the side where the transfer rack body 2 contacts the closed door 4. The first magnet 7 and the second magnet 8 attract each other and are used to fasten the closed door 4 to one side of the transfer rack body 2.
[0030] The height of the transfer rack body 2 is 35 cm, the length of the transfer rack body 2 is 6.5 cm, and the width of the transfer rack body 2 is 6.5 cm. The height of the base 1 is 0.8 cm, the length of the base 1 is 11 cm, and the width of the base 1 is 11 cm. The appropriate size facilitates the transfer rack shown in this embodiment to enter the fume hood. If it is too large, it is difficult to put it into the fume hood. If it is too small, too few sample plates will be transferred at a time, thereby reducing the efficiency of the transfer.
[0031] The transfer process of the transfer rack for transferring the X-ray powder diffraction sample plate shown in this embodiment is as follows:
[0032] The operator opens the fume hood, places the transfer rack for transferring the X-ray powder diffraction sample plate on the fume hood operating table, opens the closed door 4, places the solid powder to be tested on the X-ray powder diffraction sample plate, and then places the X-ray powder diffraction sample plate with the solid powder on the horizontal plate 5 and enters the sample plate accommodating cavity 3. After 16 sample plate accommodating cavities 3 are filled, the closed door 4 is closed, and the transfer rack for transferring the X-ray powder diffraction sample plate is transferred to the X-ray diffractometer for testing.
[0033] In summary, the above embodiments are only preferred embodiments of the present invention and are not intended to limit the protection scope of the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.
Claims
1. A transfer rack for transferring an X-ray powder diffraction sample plate, characterized in that: The transfer rack for transferring X-ray powder diffraction sample plates includes a base and a transfer rack body, wherein the transfer rack body is fixedly installed on the top of the base, and a plurality of sample plate accommodating cavities are arranged in the transfer rack body, wherein the plurality of sample plate accommodating cavities are arranged longitudinally, and the sample plate accommodating cavities are used to place the X-ray powder diffraction sample plates to be transferred, and a closed door is provided on one side of the transfer rack body, and the closed door is used to completely close the transfer rack body.
2. The transfer rack for transferring X-ray powder diffraction sample plates according to claim 1, characterized in that: The transfer rack body is a rectangular parallelepiped, the bottom surface of the transfer rack body coincides with the top surface of the base, the interior of the transfer rack body is a cavity, a plurality of parallel horizontal plates are fixedly installed in the cavity, and the plurality of horizontal plates are arranged longitudinally to divide the cavity into a plurality of sample plate accommodating cavities, each of which can hold an X-ray powder diffraction sample plate.
3. The transfer rack for transferring X-ray powder diffraction sample plates according to claim 2, characterized in that: A recessed portion is arranged on one side of the horizontal plate close to the closed door. The recessed portion is in a U-shape, and the recessed portion facilitates operators to remove the X-ray powder diffraction sample plate.
4. The transfer rack for transferring X-ray powder diffraction sample plates according to claim 1, characterized in that: A hinge is fixedly installed on one side of the closed door, and the closed door is rotatably installed on one side of the transfer frame body through the hinge.
5. The transfer rack for transferring X-ray powder diffraction sample plates according to claim 1, characterized in that: A groove is arranged on the inner side of the top end of the transfer rack body, a groove is arranged on the top of the base, and the closed door is slidably mounted on one side of the transfer rack body through the groove.
6. The transfer rack for transferring X-ray powder diffraction sample plates according to claim 1, characterized in that: A first magnet is arranged on the side where the closed door contacts the transfer rack body, and a second magnet is also arranged on the side where the transfer rack body contacts the closed door. The first magnet and the second magnet attract each other to fasten the closed door to one side of the transfer rack body.
7. The transfer rack for transferring X-ray powder diffraction sample plates according to claim 1, characterized in that: The number of the sample plate accommodating cavities is 3-16.
8. The transfer rack for transferring X-ray powder diffraction sample plates according to claim 1, characterized in that: The height of the transfer rack body is 30-40 cm, the length of the transfer rack body is 6-8 cm, and the width of the transfer rack body is 6-8 cm.
9. The transfer rack for transferring X-ray powder diffraction sample plates according to claim 1, characterized in that: The height of the base is 0.5-1.5 cm, the length of the base is 10-12 cm, and the width of the base is 10-12 cm.
10. The transfer rack for transferring X-ray powder diffraction sample plates according to claim 1, characterized in that: A silicone gasket is arranged at the bottom of the base.