Immune cell cryopreservation device

Abstract

The utility model relates to the technical field of cryopreservation devices, in particular to an immune cell cryopreservation device which comprises a base. The upper box body is connected with the base; the supporting plates are located on the side, away from the upper box body, of the base, one ends of the supporting plates are fixedly connected with the base, and the number of the supporting plates is four; the lower box body is located among the four supporting plates and fixedly connected with the side, away from the upper box body, of the base; the placing assembly is arranged in the upper box body; the sliding assembly is arranged in the upper box body and is connected with the placing assembly; the driving assembly is arranged in the lower box body and is connected with the sliding assembly; and the control assembly is arranged on the upper box body and is connected with the sliding assembly. According to the utility model, through the application of the control assembly and the driving assembly, only the cryopreservation device which needs to extract the cell sample is opened when the cell sample is extracted, and then the test tube filled with the cell sample automatically ascends.

Description

Technical Field

[0001] The utility model relates to the technical field of cryopreservation devices, in particular to an immune cell cryopreservation device. Background Art

[0002] In many biomedical experiments, cell samples need to be stored for a long time so that they can be tested and recorded at any time. In order to extend the storage time of cells, low temperature storage is usually adopted. At a lower temperature, the biological activity of cells will be greatly slowed down, thereby extending the storage time of cells.

[0003] At present, the internal space of the existing cryopreservation device is not clearly divided. When the staff extracts one or more cell samples, the cryopreservation device is always in the open state. The cryopreservation device is closed only after the required samples are extracted. In this process, it is easy to cause the internal cold to be lost, causing the sample to heat up, which is very unfavorable for the storage of other samples.

[0004] Secondly, the temperature inside the freezing device is extremely low, and it is easy for workers to get frostbite on their hands when they extract test tubes containing cell samples directly from the freezing device. Utility Model Content

[0005] The utility model provides an immune cell freezing device, which realizes that when extracting cell samples, only the freezing device where the cell sample needs to be extracted is opened through the application of a control component and a driving component, and then the test tube containing the cell sample is automatically raised, thereby avoiding manual extraction of samples directly inside the freezing device, which may cause frostbite to the hands.

[0006] In order to solve the above technical problems, the technical solution of the utility model is as follows:

[0007] The embodiment of the utility model provides an immune cell freezing device, comprising:

[0008] Base;

[0009] An upper box body connected to the base;

[0010] A support plate, located on a side of the base away from the upper box body, and one end of which is fixedly connected to the base, wherein four support plates are provided in a circular array with the center of the base as the central axis;

[0011] A lower box body, located between the four support plates and fixedly connected to a side of the base away from the upper box body;

[0012] A placement component, disposed in the upper box, for placing a test tube containing immune cells;

[0013] A sliding assembly is disposed in the upper box body and connected to the placement assembly to drive the placement assembly to slide;

[0014] A driving assembly is disposed in the lower box body and connected to the sliding assembly to drive the sliding assembly to work;

[0015] The control component is arranged on the upper box body and connected to the sliding component, and is used for controlling the connection and disconnection between the sliding component and the driving component.

[0016] Further, the placement component includes:

[0017] A slide cylinder is located inside the upper box body, and one end of the slide cylinder is connected to the base, and the other end of the slide cylinder is fixedly connected to a side of the upper box body away from the base, wherein the slide cylinder is provided with a first slide groove;

[0018] A first sliding block; the first sliding block is in an I-shaped shape and is slidably engaged with the first sliding groove;

[0019] A support seat, located in the slide cylinder and fixedly connected to one end of the first slide block close to the base;

[0020] The support frame is located at a side of the support seat away from the base and is connected to the first sliding block.

[0021] Furthermore, the sliding assembly includes:

[0022] A second sliding block is fixedly connected to a side of the first sliding block away from the sliding cylinder;

[0023] A second slide groove is provided on the slide cylinder and is slidably connected with the second sliding block;

[0024] A threaded rod has one end threadedly passing through the second sliding block to be connected to the base, and the other end connected to one side of the upper box body.

[0025] Furthermore, the driving assembly includes:

[0026] A motor is arranged in the lower box;

[0027] A first rotating rod, one end of which is connected to the output end of the motor and the other end of which is connected to a first gear;

[0028] A second rotating rod, one end of which passes through the base and is fixedly connected to one end of the threaded rod;

[0029] A U-shaped mounting block is sleeved on the second rotating rod, and one side of the U-shaped mounting block is fixedly connected to the base, wherein two sets of second limiting rings are symmetrically arranged on the inner wall of the U-shaped mounting block;

[0030] The second gear is located between the two groups of the second limiting rings, and two groups of the first limiting rings are arranged on both sides, and the two groups of the first limiting rings are respectively sleeved in the two groups of the second limiting rings, wherein the second gear is connected to the second rotating rod through a limiting member, and the second gear is meshed with the first gear.

[0031] Furthermore, the limiting element includes:

[0032] Two sets of first limiting grooves are provided and are symmetrically opened on the second rotating rod;

[0033] There are two groups of first limiting blocks, which are symmetrically arranged on the second gear, wherein the two groups of the first limiting blocks are slidably connected to the two groups of the first limiting grooves respectively.

[0034] Furthermore, the control component includes:

[0035] A control rod, one end of which passes through the upper box body and is fixedly connected to the other end of the threaded rod, and the other end of which is fixedly connected to a T-shaped sleeve, wherein two sets of third sliding grooves are symmetrically opened on both sides of the T-shaped sleeve;

[0036] A second spring is sleeved on the control rod, one end of which is connected to the sleeve, and the other end of which is connected to a reset member, wherein the reset member is sleeved on the control rod and connected to the upper box body;

[0037] A third sliding block is slidably connected to the third sliding groove, one side of which passes through the outer wall of the T-shaped sleeve and is connected to a disc, and the other side of which is connected to a second limiting block, wherein the second limiting block passes through the inner wall of the T-shaped sleeve and extends to the inside of the T-shaped sleeve;

[0038] The first spring is sleeved on the third sliding block.

[0039] Furthermore, the reset element includes:

[0040] A second sleeve, one end of which is connected to the upper box body;

[0041] A first sleeve, one end of which is connected to the other end of the second sleeve;

[0042] A hemispherical cap, sleeved on the other end of the first sleeve and connected to the second spring;

[0043] The fourth sliding block is located between the second sleeve and the hemispherical cap and is slidably sleeved on the first sleeve.

[0044] The above solution of the utility model includes at least the following beneficial effects:

[0045] The utility model is provided with a placement component, and when storing or extracting cell samples, the test tube containing the cell sample can be fixed. By providing a control component and a drive component, the cell sample to be extracted can be controlled to rise to the outside of the freezing device, and the cell samples that do not need to be extracted can be kept still, thereby avoiding the loss of cold inside the freezing device for storing other cell samples that do not need to be extracted and avoiding the staff from directly putting their hands into the freezing device and causing frostbite on the hands. BRIEF DESCRIPTION OF THE DRAWINGS

[0046] Figure 1 It is a three-dimensional diagram of the immune cell freezing device of the utility model;

[0047] Figure 2 This is a first partial schematic diagram of the immune cell freezing device of the utility model;

[0048] Figure 3 This is an exploded view of the sliding assembly of the immune cell freezing device of the utility model;

[0049] Figure 4 yes Figure 3 Enlarged view of point A in the middle;

[0050] Figure 5 This is a second partial schematic diagram of the immune cell freezing device of the utility model;

[0051] Figure 6 It is a partial schematic diagram of the control component of the immune cell freezing device of the utility model;

[0052] Figure 7 It is an exploded view of the control assembly of the immune cell freezing device of the utility model;

[0053] Figure 8 It is an exploded view of the reset part of the immune cell freezing device of the utility model.

[0054] Description of reference numerals:

[0055] 1. Upper box; 2. Base; 3. Lower box; 4. Support plate; 11. Slide; 12. First slide groove; 13. First slider; 14. Support seat; 15. Support frame; 16. Threaded rod; 17. Second slider; 18. Second slide groove; 21. Motor; 22. First rotating rod; 23. First gear; 24. Second gear; 25. First limit block; 26. First limit ring; 27. Second rotating rod; 28. First limit groove; 29. ​​Second limit ring; 30. U-shaped mounting block; 31. T-shaped sleeve; 32. Third slide groove; 33. Disc; 34. Third slider; 35. Second limit block; 36. First spring; 37. Control rod; 38. Second spring; 41. Hemispherical cap; 42. Fourth slider; 43. First sleeve; 44. Second sleeve. DETAILED DESCRIPTION

[0056] The exemplary embodiments of the present invention will be described in more detail below with reference to the accompanying drawings. Although the exemplary embodiments of the present invention are shown in the accompanying drawings, it should be understood that the present invention can be implemented in various forms and should not be limited by the embodiments described herein. On the contrary, these embodiments are provided to enable a more thorough understanding of the present invention and to fully convey the scope of the present invention to those skilled in the art.

[0057] like Figures 1 to 8 As shown, an embodiment of the utility model provides an immune cell freezing device, comprising: a base 2; an upper box body 1, connected to the base 2; a support plate 4, located on a side of the base 2 away from the upper box body 1, and one end of which is fixedly connected to the base 2, wherein four support plates 4 are provided, and are arranged in a circular array with the center of the base 2 as the center axis; a lower box body 3, located between the four support plates 4, and fixedly connected to a side of the base 2 away from the upper box body 1; a placement component, arranged in the upper box body 1, for placing a test tube containing immune cells; a sliding component, arranged in the upper box body 1, and connected to the placement component, for driving the placement component to slide; a driving component, arranged in the lower box body 3, and connected to the sliding component, for driving the sliding component to work; a control component, arranged on the upper box body 1, and connected to the sliding component, for controlling the connection and disconnection of the sliding component with the driving component.

[0058] In the embodiment of the utility model, the placement component, the sliding component, the driving component and the control component are all arranged in four groups in a circular array with the center of the base 2 as the central axis. First, open the cover of the placement component containing the sample to be extracted, then connect the sliding component and the driving component through the control component, and then start the motor 21. The sliding component can make the test tube containing the sample in the placement component rise, then take out the test tube, start the motor 21 to reset the sliding component, and then use the control component to disconnect the sliding component and the driving component.

[0059] like Figures 1 to 8 As shown, the placement component includes: a slide 11, which is located inside the upper box 1 and fixedly connected to the base 2 at one end, and fixedly connected to a side of the upper box 1 away from the base 2 at the other end, wherein the slide 11 is provided with a first slide groove 12; a first slider 13; the first slider 13 is in the shape of an I-type and is slidably engaged with the first slide groove 12; a support seat 14, which is located inside the slide 11 and fixedly connected to one end of the first slider 13 close to the base 2; a support frame 15, which is located on a side of the support seat 14 away from the base 2 and is connected to the first slider 13.

[0060] In the embodiment of the utility model, the support seat 14 and the support frame 15 are provided to fix the test tube containing the sample, and the first slide block 13 rises and falls to drive the support seat 14 to rise and fall, thereby realizing the automatic rise and fall of the test tube containing the sample.

[0061] like Figures 1 to 8 As shown, the sliding assembly includes: a second slider 17, which is fixedly connected to the side of the first slider 13 away from the slide cylinder 11; a second slide groove 18, which is arranged on the slide cylinder 11 and is slidably connected to the second slider 17; a threaded rod 16, one end of which is threaded through the second slider 17 and is slidably connected to the base 2, and the other end is slidably connected to one side of the upper box body 1.

[0062] In the embodiment of the utility model, first, the threaded rod 16 is driven to rotate by the driving assembly, and then the second slider 17 threadedly connected to the threaded rod 16 is driven to slide on the second slide groove 18. When the second slider 17 slides, the first slider 13 fixedly connected thereto is driven to slide, thereby realizing the sliding of the first slider 13 on the first slide groove 12.

[0063] like Figures 1 to 8 As shown, the driving assembly includes: a motor 21, which is arranged in the lower box body 3; a first rotating rod 22, one end of which is connected to the output end of the motor 21, and the other end is connected to the first gear 23; a second rotating rod 27, one end of which passes through the base 2 and is fixedly connected to one end of the threaded rod 16; a U-shaped mounting block 30, which is sleeved on the second rotating rod 27, and one side is fixedly connected to the base 2, wherein two groups of second limiting rings 29 are symmetrically arranged on the inner wall of the U-shaped mounting block 30; a second gear 24, which is located between the two groups of the second limiting rings 29, and two groups of first limiting rings 26 are arranged on both sides, and the two groups of the first limiting rings 26 are respectively sleeved in the two groups of the second limiting rings 29, wherein the second gear 24 is connected to the second rotating rod 27 through a limiting member, and the second gear 24 is meshed with the first gear 23.

[0064] In the embodiment of the utility model, first, the motor 21 is started, and the output end of the motor 21 drives the first rotating rod 22 to rotate, and then the first rotating rod 22 drives the first gear 23 fixedly connected thereto to rotate, and the first gear 23 then drives the second gear 24 meshing therewith to rotate, and the rotation of the second gear 24 then drives the second rotating rod 27 connected thereto through a limiting member to rotate, and then drives the threaded rod 16 to rotate, thereby realizing the lifting and lowering of the second slider 17 on the threaded rod 16, wherein the second gear 24 always maintains a meshing state with the first gear 23 through the cooperation of the first limiting ring 26, the second limiting ring 29 and the U-shaped mounting block 30.

[0065] like Figures 1 to 8As shown, the limiting component includes: two groups of first limiting grooves 28, which are symmetrically opened on the second rotating rod 27; two groups of first limiting blocks 25, which are symmetrically arranged on the second gear 24, wherein the two groups of the first limiting blocks 25 are slidably connected to the two groups of the first limiting grooves 28 respectively.

[0066] In the embodiment of the utility model, in the initial state, the first limit groove 28 and the first limit block 25 are not connected. When using the control component, the second rotating rod 27 is pushed into the second gear 24. At this time, the first limit groove 28 and the first limit block 25 are slidably engaged. When the motor 21 is started again, the second gear 24 rotates through the first limit groove 28 and the first limit block 25 to transmit power to the second rotating rod 27, thereby realizing the work of the threaded rod 16 fixedly connected to the second rotating rod 27.

[0067] like Figures 1 to 8 As shown, the control assembly includes: a control rod 37, one end of which passes through the upper box body 1 and is fixedly connected to the other end of the threaded rod 16, and the other end is fixedly connected to a T-shaped sleeve 31, wherein two groups of third sliding grooves 32 are symmetrically opened on both sides of the T-shaped sleeve 31; a second spring 38, which is sleeved on the control rod 37, one end of which is connected to the sleeve, and the other end is connected to a reset member, wherein the reset member is sleeved on the control rod 37 and connected to the upper box body 1; a third slider 34, which is slidably connected to the third sliding groove 32, one side of which passes through the outer wall of the T-shaped sleeve 31 and is connected to a disc 33, and the other side of which is connected to a second limit block 35, wherein the second limit block 35 passes through the inner wall of the T-shaped sleeve 31 and extends to the inside of the T-shaped sleeve 31; a first spring 36, which is sleeved on the third slider 34.

[0068] In the embodiment of the utility model, first, the T-sleeve 31 is pressed down, the control rod 37 descends, and then the control rod 37 drives the threaded rod 16 to descend, and at the same time, the second spring 38 sleeved on the control rod 37 is compressed, thereby connecting the second rotating rod 27 and the second gear 24, so that the power is transmitted to the threaded rod 16 through the second gear 24 and the second transmission rod, so that the threaded rod 16 works, and at the same time the second limit block 35 will also descend. During the contact process between the second limit block 35 and the reset member, the third slider 34 will slide on the third slide groove 32, thereby compressing the first spring 36. When the second limit block 35 and the reset member are not in contact, the elastic force of the extension of the first spring 36 resets the second limit block 35, thereby releasing the T-sleeve 31. Due to the elastic force of the extension of the second spring 38, the T-sleeve 31 is driven to rise, thereby causing the second limit block 35 to get stuck with the reset button, thereby achieving the second gear 24 and the second rotating rod 27 to remain connected.

[0069] like Figures 1 to 8As shown, the reset member includes: a second sleeve 44, one end of which is fixedly connected to the upper box body 1; a first sleeve 43, one end of which is fixedly connected to the other end of the second sleeve 44; a hemispherical cap 41, which is sleeved on the other end of the first sleeve 43 and fixedly connected to the second spring 38; a fourth slider 42, which is located between the second sleeve 44 and the hemispherical cap 41, and is slidably sleeved on the first sleeve 43.

[0070] In the embodiment of the utility model, the fourth slider 42 is shaped as a conical cone that is symmetrical up and down, and the upper part just fits with the inside of the hemispherical cap 41. When resetting, press the T-sleeve 31 again to make the second limit block 35 contact the fourth slider 42. When the second limit block 35 slides to the lower part of the fourth slider 42, release the T-sleeve 31, and the second limit block 35 rises while driving the fourth slider 42 to rise. When the fourth slider 42 rises to fit with the hemispherical cap 41, it pushes the second limit block 35 to slide in the third slide groove 32. When the second limit block 35 just contacts with the largest outer circle of the second slider, it will detach from the hemispherical cap 41 and disconnect from the reset member, thereby disconnecting the second rotating rod 27 and the second gear 24, thereby realizing the reset of the drive assembly.

[0071] Working principle: When using the utility model, the staff first presses the T-sleeve 31 corresponding to the cell sample to be taken out, so that the control rod 37 can be lowered, and then the control rod 37 drives the threaded rod 16 to descend, and at the same time, the second spring 38 sleeved on the control rod 37 is compressed, so that the second rotating rod 27 and the second gear 24 are connected, and at the same time, the second limit block 35 will also descend. During the contact process between the second limit block 35 and the hemispherical cap 41, the third slider 34 will slide on the third slide groove 32, so that the first spring 36 is compressed. When the second limit block 35 and the reset member are not in contact, the elastic force of the extension of the first spring 36 resets the second limit block 35, and then releases the T-sleeve 31. Due to the elastic force of the extension of the second spring 38, the T-sleeve 31 is driven to rise, so that the second limit block 35 and the hemispherical cap 41 are stuck, so that the second rotating rod 27 and the second gear 24 are always connected, and then the cover on the corresponding placement component is opened. The motor 21 is started, and the output end of the motor 21 drives the first rotating rod 22 fixedly connected thereto to rotate, and then the first rotating rod 22 drives the first gear 23 fixedly connected thereto to rotate, and the first gear 23 drives the second gear 24 meshing therewith to rotate, and the rotation of the second gear 24 drives the second rotating rod 27 connected thereto through the first limiting groove 28 and the first limiting block 25 to rotate, thereby driving the threaded rod 16 fixedly connected to the second rotating rod 27 to rotate, and then the threaded rod 16 drives the second slider 17 threadedly connected thereto to rise on the second slide groove 18, and at the same time, the second slider 17 drives the first slider 13 fixedly connected thereto to rise on the first slide groove 12, and then the first slider 13 drives the fixedly connected support seat 14 and the support frame 15 to rise, thereby realizing that the test tube containing the cell sample to be taken out is automatically raised to the outside of the freezing device, and the samples that do not need to be extracted are kept still, to avoid frostbite caused by people directly putting their hands into the freezing device.

[0072] The above is a preferred embodiment of the present invention. It should be pointed out that, for ordinary technicians in this technical field, several improvements and modifications can be made without departing from the principles of the present invention. These improvements and modifications should also be regarded as the protection scope of the present invention.

Claims

1. An immune cell freezing device, characterized in that: include: Base (2); An upper box body (1) connected to the base (2); A support plate (4) is located on a side of the base (2) away from the upper box body (1), and one end of the support plate is fixedly connected to the base (2), wherein four support plates (4) are provided and arranged in a circular array with the center of the base (2) as the central axis; A lower box body (3) is located between the four support plates (4) and is fixedly connected to a side of the base (2) away from the upper box body (1); A placement component, disposed in the upper box (1), for placing a test tube containing immune cells; A sliding component is arranged in the upper box (1) and connected to the placement component; A driving assembly, disposed in the lower box (3) and connected to the sliding assembly; A control component is arranged on the upper box body (1) and is connected to the sliding component.

2. The immune cell freezing device according to claim 1, characterized in that: The placement component comprises: A slide cylinder (11) is located inside the upper box body (1), and one end of the slide cylinder is connected to the base (2), and the other end of the slide cylinder is fixedly connected to a side of the upper box body (1) away from the base (2), wherein the slide cylinder (11) is provided with a first slide groove (12); A first sliding block (13) slidably engaged with the first sliding groove (12); A support seat (14) is located in the slide cylinder (11) and is fixedly connected to an end of the first slide block (13) close to the base (2); The support frame (15) is located on a side of the support seat (14) away from the base (2) and is connected to the first sliding block (13).

3. The immune cell freezing device according to claim 2, characterized in that: The sliding assembly comprises: A second sliding block (17) fixedly connected to a side of the first sliding block (13) away from the sliding cylinder (11); A second sliding groove (18) is provided on the sliding cylinder (11) and is slidably connected to the second sliding block (17); A threaded rod (16) has one end threadedly passing through the second sliding block (17) to be connected to the base (2), and the other end connected to one side of the upper box body (1).

4. The immune cell freezing device according to claim 3, characterized in that: The drive assembly comprises: A motor (21) is disposed in the lower box (3); A first rotating rod (22), one end of which is connected to the output end of the motor (21), and the other end of which is connected to a first gear (23); A second rotating rod (27), one end of which passes through the base (2) and is fixedly connected to one end of the threaded rod (16); A U-shaped mounting block (30) is sleeved on the second rotating rod (27), and one side of the U-shaped mounting block (30) is fixedly connected to the base (2), wherein two groups of second limiting circular rings (29) are symmetrically arranged on the inner wall of the U-shaped mounting block (30); The second gear (24) is located between the two groups of the second limiting circular rings (29), and two groups of the first limiting circular rings (26) are arranged on both sides. The two groups of the first limiting circular rings (26) are respectively sleeved in the two groups of the second limiting circular rings (29), wherein the second gear (24) is connected to the second rotating rod (27) through a limiting member, and the second gear (24) is meshed with the first gear (23).

5. The immune cell freezing device according to claim 4, characterized in that: The limiting elements include: Two groups of first limiting grooves (28) are provided and are symmetrically opened on the second rotating rod (27); Two groups of first limit blocks (25) are provided and are symmetrically arranged on the second gear (24), wherein the two groups of the first limit blocks (25) are slidably connected to the two groups of the first limit grooves (28) respectively.

6. The immune cell freezing device according to claim 5, characterized in that: The control component comprises: A control rod (37), one end of which passes through the upper box body (1) and is fixedly connected to the other end of the threaded rod (16), and the other end of which is fixedly connected to a T-shaped sleeve (31), wherein two sets of third sliding grooves (32) are symmetrically formed on both sides of the T-shaped sleeve (31); a second spring (38) sleeved on the control rod (37), one end of which is connected to the sleeve and the other end of which is connected to a reset member, wherein the reset member is sleeved on the control rod (37) and connected to the upper box (1); A third sliding block (34) is slidably connected to the third sliding groove (32), one side of which passes through the outer wall of the T-shaped sleeve (31) and is connected to a disc (33), and the other side of which is connected to a second limiting block (35), wherein the second limiting block (35) passes through the inner wall of the T-shaped sleeve (31) and extends into the interior of the T-shaped sleeve (31); The first spring (36) is sleeved on the third sliding block (34).

7. The immune cell freezing device according to claim 6, characterized in that: The reset element comprises: A second sleeve (44), one end of which is connected to the upper box body (1); A first sleeve (43), one end of which is connected to the other end of the second sleeve (44); A hemispherical cap (41) is sleeved on the other end of the first sleeve (43) and is connected to the second spring (38); The fourth sliding block (42) is located between the second sleeve (44) and the hemispherical cap (41), and is slidably sleeved on the first sleeve (43).

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