Biopsy forceps and biopsy system

The biopsy forceps with a through hole for the guide wire improve lesion access precision and reduce surgery complexity by maintaining alignment and structural integrity, addressing guide tube detachment and deformation challenges.

CN222265297UActive Publication Date: 2024-12-31CANCER INST & HOSPITAL CHINESE ACADEMY OF MEDICAL SCI +1
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Patent Information

Application Number
CN202321960463.3
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2023-07-25
Publication Date
2024-12-31
Estimated Expiration
2033-07-25

AI Technical Summary

Technical Problem

Biopsy forceps often suffer from guide tubes falling off and deformation, leading to poor parallelism with the clamp body, increasing operation difficulty and prolonging procedure time due to misalignment with the lesion.

Method used

The biopsy forceps feature a through hole in the forceps head assembly to allow a guide wire to pass through, ensuring parallelism and accurate lesion targeting, with features like rounded or hemispherical distal ends and reinforcing ribs to maintain structural integrity.

Benefits of technology

This design enhances operational convenience by enabling precise lesion access, reducing surgery difficulty and time, and preventing guide tube detachment and deformation issues.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to biopsy forceps and a biopsy system.The biopsy forceps comprise a catheter and a forceps head assembly capable of being opened and closed, the forceps head assembly is used for clamping target tissue, the forceps head assembly is arranged at the far end of the catheter, and a through hole allowing a guide wire to pass through is formed in the forceps head assembly. According to the biopsy forceps, the through hole for the guide wire to pass through is formed in the forceps head assembly, so that the forceps head assembly can accurately reach a focus under the guidance of the guide wire, the operation convenience is improved, and the operation difficulty is reduced; the problem that the short guide tube falls off and the problem that the forceps head assembly cannot reach the focus smoothly due to deformation of the short guide tube can be solved.
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Description

Technical Field

[0001] The present application relates to the technical field of medical devices, and in particular to a biopsy forceps and a biopsy system. Background Art

[0002] Biopsy forceps are an essential tool for endoscopic examinations and pathological specimen collection. They are inserted through the endoscope lumen to reach the lesion, grasp the pathological tissue, and then withdraw it from the body. The biopsy forceps must be guided and supported by a guide wire to successfully reach the lesion.

[0003] In the related art, in order to facilitate operation, a guide tube is usually bonded or welded to the biopsy forceps, and the guide tube is used for allowing a guide wire to pass through.

[0004] However, the above-mentioned guide tube is not firmly fixed on the clamp body, and there is a risk of it falling off during clinical use. In addition, the guide tube is prone to obvious deformation after being combined with the clamp body, resulting in poor parallelism between the guide tube and the clamp body, and then resulting in a large angle between the guide wire and the clamp body. This increases the difficulty of clinical operation, makes it difficult for the clamp head to reach the lesion, and prolongs the operation time. Summary of the Invention

[0005] Based on this, it is necessary to provide a living body sampling forceps and a living body sampling system to address the above technical problems.

[0006] A biopsy forceps comprises a catheter and an openable and closable forceps head assembly, wherein the forceps head assembly is used to clamp target tissue, the forceps head assembly is arranged on the distal end of the catheter, and a through hole is provided on the forceps head assembly for allowing a guide wire to pass through.

[0007] The above-mentioned living body sampling forceps, by providing a through hole for the guide wire to pass through on the forceps head assembly, can enable the forceps head assembly to accurately reach the lesion under the guidance of the guide wire, thereby improving the convenience of operation, reducing the difficulty of surgery, and solving the problem of the guide short tube falling off and the problem of the forceps head assembly being unable to reach the lesion smoothly due to deformation of the guide short tube.

[0008] In one embodiment, the distribution direction of the through holes is parallel to the axial direction of the pliers head assembly.

[0009] In one embodiment, the distal end surface of the pliers head assembly is rounded.

[0010] In one embodiment, the distal end surface of the clamp head assembly is hemispherical.

[0011] In one embodiment, the forceps assembly includes a first clamping member and a second clamping member both rotatably disposed on the catheter, the first clamping member and the second clamping member can cooperate to clamp the target tissue, and the through hole is provided on the first clamping member.

[0012] In one embodiment, the maximum radial length L1 of the first clamping member is greater than the maximum radial length L2 of the second clamping member and is less than or equal to 2 times the maximum radial length L2 of the second clamping member.

[0013] In one embodiment, a first accommodating groove is provided on a side of the first clamping member close to the second clamping member, and a second accommodating groove is provided on a side of the second clamping member close to the first clamping member. When the clamp head assembly is closed, the second accommodating groove and the first accommodating groove can cooperate to form a clamping cavity.

[0014] In one embodiment, the first clamping member is further provided with a first pressure relief hole communicating with the first accommodating groove, and the second clamping member is further provided with a second pressure relief hole communicating with the second accommodating groove.

[0015] In one embodiment, a first reinforcing rib is provided on a side of the first clamping member close to the second clamping member, and the first reinforcing rib is arranged around the first pressure relief hole; and / or a second reinforcing rib is provided on a side of the second clamping member close to the first clamping member, and the second reinforcing rib is arranged around the second pressure relief hole.

[0016] A biopsy system comprises a guide wire and the biopsy forceps as described above, wherein the distal end of the guide wire can pass through a through hole of the biopsy forceps.

[0017] The above-mentioned living body sampling system, by providing a through hole for the guide wire to pass through on the clamp head assembly of the living body sampling forceps, can enable the clamp head assembly to accurately reach the lesion under the guidance of the guide wire, thereby improving the convenience of operation, reducing the difficulty of surgery, and solving the problem of the guide short tube falling off and the problem of the clamp head assembly being unable to reach the lesion smoothly due to deformation of the guide short tube. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 This is a schematic diagram of the three-dimensional structure of the distal end of the biopsy forceps provided in one embodiment of the present application in a closed state after being assembled with a guide wire.

[0019] Figure 2 This is a schematic diagram of the three-dimensional structure of the distal end of the biopsy forceps provided in one embodiment of the present application in an open state after being assembled with a guide wire.

[0020] Figure 3 A schematic diagram of the three-dimensional structure of the proximal end of the biopsy forceps provided in one embodiment of the present application.

[0021] Figure 4 A simplified diagram of the internal structure of the proximal end of the biopsy forceps provided in one embodiment of the present application.

[0022] The reference numerals in the accompanying drawings are described as follows:

[0023] 10. Biopsy forceps; 100. Catheter; 200. Forceps head assembly; Through hole; 210. First clamping member

[0024] 210; 210a, first pressure relief hole; 220, second clamping member; 220a, second accommodating groove; 220b, second pressure relief hole; 221, second reinforcing rib; 300, zipper; 400, handle assembly; 410, core rod; 410a, guide hole; 420, sliding sleeve; 430, sliding core; 500, clamping frame; 500a, avoidance groove; 600, connecting rod assembly; 610, first connecting rod; 620, second connecting rod; 630, third connecting rod; 640, fourth connecting rod; 20, guide wire. DETAILED DESCRIPTION

[0025] To make the above-mentioned objects, features, and advantages of the present application more clearly understood, the specific embodiments of the present application are described in detail below with reference to the accompanying drawings. The following description sets forth many specific details to facilitate a full understanding of the present application. However, the present application can be implemented in many other ways than those described herein, and those skilled in the art can make similar improvements without violating the scope of the present application. Therefore, the present application is not limited to the specific embodiments disclosed below.

[0026] In the description of this application, it should be understood that if the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise", "axial", "radial", "circumferential", etc. appear, the orientation or position relationship indicated by these terms is based on the orientation or position relationship shown in the accompanying drawings, which is only for the convenience of describing this application and simplifying the description, and does not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on this application.

[0027] In addition, if the terms "first" or "second" appear, these terms are used for descriptive purposes only and should not be understood to indicate or imply relative importance or implicitly specify the number of technical features indicated. Therefore, a feature specified as "first" or "second" may explicitly or implicitly include at least one of such features. In the description of this application, if the term "plurality" appears, "plurality" means at least two, for example, two, three, etc., unless otherwise specifically defined.

[0028] In this application, unless otherwise specified or limited, the terms "mounted," "connected," "connected," "fixed," etc., should be interpreted broadly. For example, these terms may refer to fixed connections, removable connections, or integration; mechanical connections or electrical connections; direct connections or indirect connections through an intermediary; and internal communication between two components or interaction between two components, unless otherwise specified. Those skilled in the art will understand the specific meanings of these terms in this application based on the specific circumstances.

[0029] In this application, unless otherwise expressly specified or limited, if a first feature is described as being "above" or "below" a second feature, or similar descriptions, this may mean that the first and second features are in direct contact, or that the first and second features are in indirect contact through an intermediate medium. Furthermore, when a first feature is described as being "above," "above," or "above" a second feature, it may mean that the first feature is directly above or diagonally above the second feature, or simply means that the first feature is at a higher level than the second feature. When a first feature is described as being "below," "below," or "below" a second feature, it may mean that the first feature is directly below or diagonally below the second feature, or simply means that the first feature is at a lower level than the second feature.

[0030] It should be noted that if an element is referred to as being "fixed to" or "disposed on" another element, it may be directly on the other element or there may be an intermediate element. If an element is considered to be "connected to" another element, it may be directly connected to the other element or there may be an intermediate element. If any, the terms "vertical", "horizontal", "upper", "lower", "left", "right" and similar expressions used in this application are for illustrative purposes only and do not represent the only embodiment.

[0031] It should be noted that the terms “distal end” and “proximal end” throughout the text are only used to indicate relative positional relationships. The “distal end” of a component refers to the end that enters the patient’s body first compared to the other end during normal operation and / or the end that is farther away from the operator, while the “proximal end” refers to the end that enters the patient’s body later than the other end and / or the end that is closer to the operator.

[0032] Referring to the figure, an embodiment of the present application provides a living body sampling forceps 10, which includes a catheter 100 and an openable and closable forceps head assembly 200. The forceps head assembly 200 is used to clamp the target tissue. The forceps head assembly 200 is arranged on the distal end of the catheter 100, and the forceps head assembly 200 is provided with a through hole for allowing a guide wire 20 to pass through.

[0033] The above-mentioned biopsy forceps 10 can enter the narrow cavity (such as the bile duct) in the patient's body to perform biopsy. Of course, the above-mentioned biopsy forceps 10 can also enter other diseased parts in the patient's body, such as the pancreas, kidney, liver, lung, etc. The following describes how the biopsy forceps 10 cooperates with the guide wire 20, taking the entry into the bile duct as an example: first, the distal end of the guide wire 20 is passed through the through hole on the clamp head assembly 200 of the biopsy forceps 10, and then the clamp head assembly 200 and the guide wire 20 are entered into the bile duct together, and then the guide wire 20 is operated to pre-insert it into the nipple of the lesion, and then the biopsy forceps 10 is passed through the through hole on the clamp head assembly 200 along the guide wire 20 to accurately reach the nipple of the lesion, and then the clamp head assembly 200 can be operated to align it with the nipple and perform sampling.

[0034] The above-mentioned living body sampling forceps 10, by providing a through hole for the guide wire 20 to pass through on the forceps head assembly 200, can enable the forceps head assembly 200 to accurately reach the lesion under the guidance of the guide wire 20, thereby improving the convenience of operation, reducing the difficulty of surgery, and solving the problem of the guide short tube falling off and the problem of the forceps head assembly 200 being unable to reach the lesion smoothly due to deformation of the guide short tube.

[0035] See also Figure 1 In some embodiments of the present application, the through-holes may be arranged in a direction parallel to the axial direction of the forceps head assembly 200. This arrangement of the through-holes ensures parallelism between the forceps head assembly 200 and the guide wire 20, ensuring that the forceps head assembly 200 can smoothly reach the nipple of the lesion along the guide wire 20. It is understood that the through-holes may extend from the proximal end of the forceps head assembly 200 to the distal end of the forceps head assembly 200.

[0036] It should be noted that the cross-sectional profile of the through hole should be compatible with the cross-sectional profile of the guide wire 20. For example, if the cross-section of the guide wire 20 is circular, the cross-sectional profile of the through hole is also circular, and the aperture of the through hole is equal to or slightly larger than the outer diameter of the guide wire 20; for another example, if the cross-sectional profile of the guide wire 20 is rectangular, the cross-sectional profile of the through hole is also rectangular, and the aperture of the through hole is equal to or slightly larger than the outer diameter of the guide wire 20.

[0037] Furthermore, in some embodiments of the present application, the clamp head assembly 200 may be made of metal, such as stainless steel or titanium alloy. The metal clamp head assembly 200 is not easily deformed, and can ensure the parallelism between the clamp head assembly 200 and the guide wire 20.

[0038] In some embodiments of the present application, the catheter 100 may be made of a flexible material, such as PU (Polyurethane) or Pebax (polyether block polyamide). The flexible material of the catheter 100 facilitates delivery within the patient's body.

[0039] See also Figure 1 In some embodiments of the present application, the distal end surface of the forceps head assembly 200 may be rounded. This configuration of the distal end surface of the forceps head assembly 200 ensures that the distal end of the guide wire 20 will not be scratched by the distal end of the forceps head assembly 200 after passing through the through hole in the forceps head assembly 200. Alternatively, the distal end surface of the forceps head assembly 200 may be hemispherical.

[0040] See also Figure 2 In some embodiments of the present application, the forceps assembly 200 may include a first clamping member 210 and a second clamping member 220, both rotatably disposed on the catheter 100. The first clamping member 210 and the second clamping member 220 can cooperate to clamp the target tissue. The first clamping member 210 is provided with a through hole. It should be noted that the through hole can also be provided on the second clamping member 220.

[0041] It should be noted that when the first clamp member 210 and the second clamp member 220 rotate toward each other, the clamp head assembly 200 can be closed; when the first clamp member 210 and the second clamp member 220 rotate toward each other, the clamp head assembly 200 can be opened.

[0042] Regarding the structure of the first clamping member 210 and the second clamping member 220, the present application does not impose any specific restrictions, as long as they can effectively clamp the target tissue. For example, Figure 1 In the illustrated biopsy forceps 10 , when the first clamping member 210 and the second clamping member 220 are closed, the distal end of the clamp head assembly 200 is in a hemispherical shape, and the rest of the clamp head assembly 200 is in a cylindrical shape.

[0043] See also Figure 2In some embodiments of the present application, the maximum radial length L1 of the first clamping member 210 may be greater than the maximum radial length L2 of the second clamping member 220 and less than or equal to 2 times the maximum radial length L2 of the second clamping member 220. For example, the maximum radial length L1 of the first clamping member 210 may be 1.1 times the maximum radial length L2 of the second clamping member 220, 1.3 times the maximum radial length L2 of the second clamping member 220, 1.5 times the maximum radial length L2 of the second clamping member 220, 1.7 times the maximum radial length L2 of the second clamping member 220, 1.9 times the maximum radial length L2 of the second clamping member 220, 2.0 times the maximum radial length L2 of the second clamping member 220, etc. It should be noted that the maximum radial length L1 of the first clamping member 210 refers to the maximum height of the first clamping member 210 in a first direction, which is perpendicular to the axial direction of the first clamping member 210; the maximum radial length L2 of the second clamping member 220 refers to the maximum height of the second clamping member 220 in a second direction, which is perpendicular to the axial direction of the second clamping member 220. Setting the maximum radial length of the first clamping member 210 in this manner not only ensures that the first clamping member 210 has sufficient space to define a through hole for the guide wire 20 to pass through, but also ensures that the first clamping member 210 has a certain strength after the through hole is defined, so that it is not easily deformed, and that the overall size of the clamp head assembly 200 is not too large, thereby ensuring that the distal end of the biopsy forceps 10 can smoothly pass through a narrow cavity.

[0044] Further, in some embodiments of the present application, see Figure 2 A first receiving groove (not shown in the drawings) is provided on the side of the first clamping member 210 near the second clamping member 220. A second receiving groove 220a is provided on the side of the second clamping member 220 near the first clamping member 210. When the forceps head assembly 200 is closed, the second receiving groove 220a and the first receiving groove cooperate to form a clamping cavity. After the biopsy forceps 10 has removed the living tissue, the living tissue is accommodated in the clamping cavity of the forceps head assembly 200, facilitating smooth removal of the forceps head assembly 200 from the body.

[0045] Further, see Figure 1 and Figure 2 In some embodiments of the present application, the first clamping member 210 is further provided with a first pressure relief hole 210a communicating with the first receiving groove, and the second clamping member 220 is further provided with a second pressure relief hole 220b communicating with the second receiving groove 220a. The provision of the first pressure relief hole 210a and the second pressure relief hole 220b allows air in the clamping chamber to be discharged, allowing the first clamping member 210 and the second clamping member 220 to clamp the target tissue.

[0046] Regarding the number of the first pressure relief holes 210a, 1, 2, 3 or more can be provided, and this application does not impose any specific restrictions, as long as the pressure relief can be effectively achieved. For example, Figure 1 and Figure 2 The first clamping member 210 shown is provided with a first pressure relief hole 210 a.

[0047] Similarly, the number of the second pressure relief holes 220b can be 1, 2, 3 or more, and this application does not impose any specific restrictions, as long as the pressure relief can be effectively achieved. Figure 2 The second clamping member 220 shown is provided with a second pressure relief hole 220 b.

[0048] Regarding the shape of the first pressure relief hole 210a, it can be circular, rectangular, oblong, pentagonal, hexagonal or other polygonal shapes. This application does not impose any specific restrictions, as long as it can effectively relieve pressure. For example, Figure 1 and Figure 2 The first clamping member 210 shown is provided with an oblong first pressure relief hole 210 a.

[0049] Similarly, the second pressure relief hole 220b may be in a circular, rectangular, oblong, pentagonal, hexagonal, or other polygonal shape, and this application does not impose any specific restrictions, as long as it can effectively relieve pressure. For example, the second clamp 220 is provided with an oblong second pressure relief hole 220b.

[0050] A first reinforcing rib is further provided on one side of the first clamping member 210 close to the second clamping member 220, and the first reinforcing rib is provided around the first pressure relief hole 210a; and / or, see Figure 2 The second clamping member 220 is further provided with a second reinforcing rib 221 on a side thereof adjacent to the first clamping member 210. The second reinforcing rib 221 surrounds the second pressure relief hole 220b. The provision of the first and second reinforcing ribs 221 ensures the strength of the first clamping member 210 around the first pressure relief hole 210a and the strength of the second clamping member 220 around the second pressure relief hole 220b. Alternatively, the first reinforcing rib can be integrally formed on the first clamping member 210, and the second reinforcing rib 221 can also be integrally formed on the second clamping member 220.

[0051] See also Figure 2In some embodiments of the present application, the biopsy forceps 10 may further include a zipper 300. The distal end of the zipper 300 passes through the catheter 100 and is connected to the first clamping member 210 and / or the second clamping member 220. The zipper 300 can slide along the catheter 100 until the clamp head assembly 200 is opened or closed. As an example, the distal end of the zipper 300 can be connected to both the first clamping member 210 and the second clamping member 220. When the zipper 300 slides along the catheter 100, the first clamping member 210 and the second clamping member 220 can simultaneously rotate in a direction toward each other to close the clamp head assembly 200, or simultaneously rotate in a direction away from each other to open the clamp head assembly 200.

[0052] Further, see Figure 3 In some embodiments of the present application, the biopsy forceps 10 may further include a handle assembly 400; see Figure 4 The handle assembly 400 includes a core rod 410, a sliding sleeve 420, and a sliding core 430. The sliding core 430 is connected to the proximal end of the catheter 100. The sliding core 430 is disposed within the core rod 410 and connected to the proximal end of the zipper 300. The sliding sleeve 420 is sleeved onto the exterior of the core rod 410 and connected to the sliding core 430. The sliding sleeve 420 can slide axially along the core rod 410 and drive the sliding core 430 to slide along with it during the sliding process. The operator can push the sliding sleeve 420 to cause it to move axially along the core rod 410. The sliding core 430 then slides under the drive of the sliding sleeve 420, thereby driving the zipper 300 to slide along the catheter 100 to open or close the clamp head assembly 200.

[0053] Alternatively, see Figure 3 The core rod 410 may be provided with an axially distributed guide hole 410a, and the outer wall of the sliding core 430 may be provided with a guide block (not shown in the drawings). The guide block passes through the guide hole 410a and is connected to the sliding sleeve 420. The cooperation between the guide hole 410a and the guide block allows the sliding sleeve 420 to slide axially along the core rod 410, and during the sliding process, the sliding sleeve 420 can effectively drive the sliding core 430 to slide together.

[0054] Further, see Figure 2 In some embodiments of the present application, the biopsy forceps 10 further includes a clamp frame 500 and a connecting rod assembly 600. The clamp frame 500 is disposed on the distal end of the catheter 100. The clamp frame 500 is provided with an escape slot 500a. The connecting rod assembly 600 is disposed in the escape slot 500a. The proximal end of the connecting rod assembly 600 is hingedly connected to the zipper 300, and the distal end of the connecting rod assembly 600 is hingedly connected to the first clamp member 210 and / or the second clamp member 220, and the clamp frame 500. As an example, the distal end of the connecting rod assembly 600 is hingedly connected to both the first clamp member 210 and the second clamp member 220.

[0055] Optionally, the connecting rod assembly 600 may include a first connecting rod and a second connecting rod; Figure 2 The first connecting rod includes a first connecting rod 610 and a second connecting rod 620 that are hinged to each other, and the second connecting rod includes a third connecting rod 630 and a fourth connecting rod 640 that are hinged to each other; the distal end of the first connecting rod 610 is hinged to the first clamping member 220 and the clamp frame 500, the distal end of the third connecting rod 630 is hinged to the second clamping member 230 and the clamp frame 500, and the proximal end of the second connecting rod 620 and the proximal end of the fourth connecting rod 640 are hinged to the zipper 300.

[0056] In another embodiment of the present application, a biopsy system is provided, which includes a guide wire 20 and any one of the biopsy forceps 10 described above. The distal end of the guide wire 20 can pass through the through hole of the biopsy forceps 10 .

[0057] The above-mentioned biopsy system can enter the narrow cavity (such as the bile duct) in the patient's body to perform biopsy. Of course, the above-mentioned biopsy forceps 10 can also enter other diseased parts in the patient's body, such as the pancreas, kidney, liver, lung, etc. The following takes entering the bile duct as an example to describe how the biopsy forceps 10 cooperates with the guide wire 20: first, the distal end of the guide wire 20 is passed through the through hole on the clamp head assembly 200 of the biopsy forceps 10, and then the clamp head assembly 200 and the guide wire 20 are entered into the bile duct together, and then the guide wire 20 is operated to pre-insert it into the nipple of the lesion, and then the biopsy forceps 10 is passed through the through hole on the clamp head assembly 200 along the guide wire 20 to accurately reach the nipple of the lesion, and then the clamp head assembly 200 can be operated to align it with the nipple and perform sampling.

[0058] The above-mentioned living body sampling system, by providing a through hole for the guide wire 20 to pass through on the forceps head assembly 200, can enable the forceps head assembly 200 to accurately reach the lesion under the guidance of the guide wire 20, thereby improving the convenience of operation, reducing the difficulty of surgery, and solving the problem of the guide short tube falling off and the problem of the forceps head assembly 200 being unable to reach the lesion smoothly due to deformation of the guide short tube.

[0059] The technical features of the above-mentioned embodiments can be combined arbitrarily. In order to make the description concise, not all possible combinations of the technical features in the above-mentioned embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0060] The above-described embodiments merely represent several implementation methods of the present application. While the descriptions are relatively specific and detailed, they should not be construed as limiting the scope of the patent application. It should be noted that a person of ordinary skill in the art may make various modifications and improvements without departing from the spirit of the present application, and these modifications and improvements fall within the scope of protection of the present application. Therefore, the scope of protection of the present patent application shall be determined by the appended claims.

Claims

1. A biopsy forceps, characterized in that: The biopsy forceps (10) comprises a catheter (100) and an openable and closable forceps head assembly (200), wherein the forceps head assembly (200) is used to clamp target tissue, the forceps head assembly (200) is arranged on the distal end of the catheter (100), and the forceps head assembly (200) is provided with a through hole for allowing a guide wire (20) to pass through; The distribution direction of the through holes is parallel to the axial direction of the clamp head assembly (200); The distal end surface of the clamp head assembly (200) is rounded and smooth.

2. The biopsy forceps according to claim 1, characterized in that: The distal end surface of the clamp head assembly (200) is hemispherical.

3. The biopsy forceps according to claim 1 or 2, characterized in that: The clamp head assembly (200) comprises a first clamp member (210) and a second clamp member (220) both rotatably arranged on the catheter (100); the first clamp member (210) and the second clamp member (220) can cooperate to clamp the target tissue; the first clamp member (210) is provided with the through hole.

4. The biopsy forceps according to claim 3, characterized in that: The maximum radial length L1 of the first clamping member (210) is greater than the maximum radial length L2 of the second clamping member (220) and is less than or equal to 2 times the maximum radial length L2 of the second clamping member (220).

5. The biopsy forceps according to claim 3, characterized in that: A first receiving groove is provided on a side of the first clamp member (210) close to the second clamp member (220), and a second receiving groove (220a) is provided on a side of the second clamp member (220) close to the first clamp member (210). When the clamp head assembly (200) is closed, the second receiving groove (220a) and the first receiving groove can cooperate to form a clamping cavity.

6. The biopsy forceps according to claim 5, characterized in that: The first clamping member (210) is also provided with a first pressure relief hole (210a) communicating with the first receiving groove, and the second clamping member (220) is also provided with a second pressure relief hole (220b) communicating with the second receiving groove (220a).

7. The biopsy forceps according to claim 6, characterized in that: A first reinforcing rib is also provided on a side of the first clamping member (210) close to the second clamping member (220), and the first reinforcing rib is arranged around the first pressure relief hole (210a); and / or a second reinforcing rib (221) is also provided on a side of the second clamping member (220) close to the first clamping member (210), and the second reinforcing rib (221) is arranged around the second pressure relief hole (220b).

8. A living body sampling system, characterized in that: The biopsy system comprises a guide wire (20) and the biopsy forceps (10) according to any one of claims 1 to 7, wherein the distal end of the guide wire (20) can pass through a through hole of the biopsy forceps (10).