Mouse placing rack for experiment

By introducing a rotary drive mechanism and an adjustable limb fixation assembly into the mouse fixation device, the problem of inability to adjust the angle of the operating table in the prior art is solved, and stable fixation and flexible operation of the mice are achieved to meet different experimental needs.

CN222285686UActive Publication Date: 2025-01-03BEIJING DONGCHENG DISTRICT FIRST PEOPLES HOSPITAL
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Patent Information

Application Number
CN202420524425.1
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-03-18
Publication Date
2025-01-03
Estimated Expiration
2034-03-18

AI Technical Summary

Technical Problem

The existing mouse fixation device operator table cannot adjust the angle as needed, making it difficult to achieve during the experiment, especially intraperitoneal injection and neck surgery.

Method used

An experimental mouse placement frame including a bottom support frame and a rotary drive mechanism is designed. The operating table can adjust the tilt angle through the rotary drive mechanism, and a hollow part, a head support frame and an adjustable limb are provided on the operating table. Fixing components ensure that mice of different sizes can be fixed and adapted to different operating needs.

Benefits of technology

The rotational drive mechanism adjusts the angle of the operating table and the position of the limb fixation assembly, and the stable fixation and flexible operation of the mice are achieved, making various surgical operations convenient.

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Abstract

The utility model discloses an experimental mouse placing rack which comprises a bottom supporting frame, an operation table and a rotation driving mechanism, the rotation driving mechanism comprises a driving unit and a telescopic rod, the operation table comprises a rotation side and a driving side, the rotation side is rotationally connected to one side of the bottom supporting frame, one end of the telescopic rod is connected with the driving side, and the other end of the telescopic rod is connected with the driving side. The operation table is driven by the driving unit and the telescopic rod to rotate so as to change the inclination angle, a hollowed-out part is arranged on the operation table, a head supporting frame is arranged on the side, located on the hollowed-out part, of the operation table, and a limb fixing assembly is further arranged on the operation table. According to the mouse placing frame for the experiment, the position of the fixing piece can be adjusted according to needs, so that mice of different sizes can be fixed and limited through the fixing piece and the head supporting frame, meanwhile, the operation table is rotatably installed on the bottom supporting frame, and the operation table is convenient to use. The angle of the operating table can be adjusted through the rotary driving mechanism, the dip angle of the mouse is changed, and surgical operation is facilitated.
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Description

Technical Field

[0001] The utility model relates to the technical field of medical animal experiments, in particular to a mouse placement rack for experiments. Background Art

[0002] Stereotactic brain technology is widely used in the precise positioning of brain damage, stimulation and EEG recording, and has become an indispensable tool for studying brain structure and function. Stereotactic brain technology mainly uses a stereotaxic device as a positioning instrument, and is an important research method in the fields of neuroanatomy, neurophysiology, neuropharmacology and neurosurgery. Commonly used experimental animals, such as rats, mice, cats and other higher mammals, as well as birds, can be positioned according to the data provided by the stereotaxic brain atlas after the extracranial markers are determined. It is often used in experimental neuropsychology and neurosurgery. For example, accurately inserting microelectrodes or microcatheters or aiming rays at specific parts of the brain to stimulate, damage or inject drugs. It is widely used in experimental operations such as in vivo electrophysiology, stereotaxic injections, etc. of experimental animals such as rats and mice.

[0003] When using mice for experiments, it is necessary to use a fixing device to fix the mice, such as the utility model patent application with the authorization announcement number CN204744492U and the name of an adjustable white mouse and rabbit fixing frame, which includes a telescopic sleeve, a pin shaft, a telescopic rod, an operating table, a support rod, a fixing seat, a fixing block I, a wire rope, a fixing block II, a slider and a fixing, adjust the depth of the telescopic rod inserted into the telescopic sleeve, and then insert the pin shaft into the pin shaft hole I and the pin shaft hole II for fixing. Adjust the position of the slider in the slide groove of the operating table so that the distance between each adjustment slider is suitable for white mice or rabbits, put the mouse or rabbit claws on the white mouse or rabbit operating table, put the mouse claws or rabbit claws in the ring formed by the wire rope, pull the fixing rope, and when the fixing rope is locked, rotate the set screw II, and the mouse claws or rabbit claws are fixed. Adjust the position of the fixing seat on the support rod, put the ring formed by the wire rope on the mouse teeth or rabbit teeth, pull the wire rope, and then rotate the set screw I, and the mouse head or rabbit head is fixed.

[0004] The operating tables in the existing fixing devices are all fixed and their angles cannot be adjusted as needed, which is inconvenient for some surgical operations on mice during the experiment, such as intraperitoneal injections and surgical operations on the neck. Utility Model Content

[0005] The utility model aims to provide a mouse placement rack for experiments to solve the above-mentioned deficiencies in the prior art.

[0006] In order to achieve the above purpose, the utility model provides the following technical solutions:

[0007] A mouse placement rack for experiments, comprising a bottom support frame and an operating table arranged on the bottom support frame, and also comprising a rotation drive mechanism, wherein the rotation drive mechanism comprises a driving unit and a telescopic rod, the operating table comprises a rotating side and a driving side, the rotating side is rotatably connected to one side of the bottom support frame, one end of the telescopic rod is connected to the driving side, and the operating table is driven by the driving unit and the telescopic rod to rotate to change the tilt angle;

[0008] The operating table is provided with a hollow portion, and a head support frame is provided on one side of the hollow portion. The operating table is also provided with a limb fixing assembly, and the limb fixing assembly includes multiple fixing parts, and the multiple fixing parts can move along the preset direction of the operating table to adjust their positions.

[0009] The above-mentioned experimental mouse placement rack, the head support frame includes a lower frame body and an upper frame body, the lower frame body includes a lower support rod and a lower support plate arranged on the lower support rod, and the lower support plate is provided with a lower arc-shaped limiting groove.

[0010] The above-mentioned experimental mouse placement rack, the upper rack body includes an upper support plate and guide rods, there are two guide rods, the two guide rods are fixedly mounted on the lower support plate, and the upper support plate is adjustably mounted on the guide rods.

[0011] In the above-mentioned experimental mouse placement rack, the upper support plate is provided with an upper arc-shaped restriction groove, and the upper arc-shaped restriction groove and the lower arc-shaped restriction groove together form an adjustable circular restriction cavity.

[0012] In the above-mentioned experimental mouse placement rack, a top fixing plate is arranged on the top of the guide rod, a threaded hole is arranged on the top fixing plate, a threaded rod is rotatably arranged in the threaded hole, and the rotation of the threaded rod can drive the upper support plate to move along the guide rod.

[0013] The above-mentioned experimental mouse placement rack also includes an elastic member, which is mounted on the guide rod, and the elastic member blocks the movement of the upper support plate along the guide rod downward.

[0014] The above-mentioned experimental mouse placement rack has a strip bottom beam on the operating table, a strip slide groove on the strip bottom beam, and the fixing member includes a sliding seat and a fixing structure arranged on the sliding seat, and the sliding seat is slidably connected to the strip slide groove.

[0015] The above-mentioned experimental mouse placement rack also includes a locking piece, which is arranged on the sliding seat. The strip-shaped slide groove is provided with a locking portion along the length direction. The locking piece can fix the sliding seat at any position of the strip-shaped slide groove.

[0016] In the above technical scheme, the experimental mouse placement rack provided by the utility model includes a bottom support frame, an operating table arranged on the bottom support frame and a rotating drive mechanism, the rotating drive mechanism includes a driving unit and a telescopic rod, a hollow portion is arranged on the operating table, a head support frame is arranged on one side of the hollow portion of the operating table, a limb fixing assembly is arranged on the operating table, the limb fixing assembly includes a plurality of adjustable fixing parts, so that when in use, the position of the fixing parts can be adjusted as needed, so that the fixing parts and the head support frame can fix and restrict mice of different sizes, and at the same time, the operating table can be rotatably installed on the bottom support frame, and the angle of the operating table can be adjusted through the rotating drive mechanism to change the inclination angle of the mouse, so as to facilitate surgical operations. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings required for use in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments recorded in the present utility model. For ordinary technicians in this field, other drawings can also be obtained based on these drawings.

[0018] Figure 1 One of the structural schematic diagrams of the experimental mouse placement rack provided by the embodiment of the utility model;

[0019] Figure 2 The second structural schematic diagram of the experimental mouse placement rack provided by the embodiment of the utility model;

[0020] Figure 3 A schematic diagram of the structure of the bottom support frame provided by an embodiment of the utility model;

[0021] Figure 4 A top view of an operating table provided in an embodiment of the utility model;

[0022] Figure 5 A schematic diagram of the structure of a head support frame provided by an embodiment of the utility model;

[0023] Figure 6 A schematic structural diagram of a fixing member provided in an embodiment of the utility model.

[0024] Description of reference numerals:

[0025] 1. Bottom support frame; 10. Vertical frame; 11. Top horizontal frame; 2. Operation table; 20. Rotation side; 21. Drive side; 22. Hollow part; 3. Rotation drive mechanism; 30. Drive unit; 31. Telescopic rod; 4. Head support frame; 40. Lower frame; 400. Lower support rod; 401. Lower support plate; 402. Lower arc limiting groove; 41. Upper frame; 410. Upper support plate; 411. Guide rod; 412. Upper arc Limiting groove; 42, circular limiting cavity; 43, top fixing plate; 430, threaded rod; 44, elastic member; 5, strip bottom beam; 50, strip slide groove; 51, locking tooth groove; 6, limb fixing assembly; 61, fixing member; 62, locking member; 63, sliding seat; 630, fixing structure; 631, side limiting strip; 632, opening cavity; 633, locking channel; 64, locking block; 641, locking serration; 65, locking screw. DETAILED DESCRIPTION

[0026] In order to enable those skilled in the art to better understand the technical solution of the present invention, the present invention will be further described in detail below in conjunction with the accompanying drawings.

[0027] like Figure 1-6 As shown, the utility model provides an experimental mouse placement rack, including a bottom support frame 1, an operating table 2 arranged on the bottom support frame 1 and a rotating drive mechanism 3, the rotating drive mechanism 3 includes a driving unit 30 and a telescopic rod 31, the operating table 2 includes a rotating side 20 and a driving side 21, the rotating side 20 is rotatably connected to one side of the bottom support frame 1, one end of the telescopic rod 31 is connected to the driving side 21, and the operating table 2 is driven by the driving unit 30 and the telescopic rod 31 to rotate; a hollow portion 22 is provided on the operating table 2, a head support frame 4 is provided on one side of the hollow portion 22 of the operating table 2, a limb fixing assembly 6 is provided on the operating table 2, the limb fixing assembly 6 includes a plurality of fixing members 61, and the plurality of fixing members 61 move along a preset direction of the operating table 2 to adjust its position.

[0028] Specifically, the bottom support frame 1 includes a base and a vertical frame 10 arranged on the base. A moving component is arranged at the bottom of the base, and the movement of the bottom support frame 1 is facilitated by the moving component. A top horizontal frame 11 is arranged on the vertical frame 10. The top horizontal frame 11 is formed by connecting three beams or four beams. The operating table 2 is used to place and fix the mouse. The size of the operating table 2 is consistent with the size of the top horizontal frame 11. The two sides of the operating table 2 along the length or width direction are respectively a rotating side 20 and a driving side 21. A connecting side plate is arranged on the rotating side 20. The connecting side plate is rotatably connected to one side of the top horizontal frame 11 through a rotating shaft. A rotating drive mechanism 3 is arranged on the top horizontal frame 11. The rotary drive mechanism 3 includes a drive unit 30 and a telescopic rod 31. The drive unit 30 can drive the extension length of the telescopic rod 31 to change. The drive unit 30 can be a cylinder, and the telescopic rod 31 can be a piston matching the cylinder. In this way, the length of the rotary drive mechanism 3 formed by the drive unit 30 and the telescopic rod 31 can be changed through the movement of the drive unit 30. The end of the piston away from the cylinder is rotatably connected to the driving side 21 of the operating table 2, and the cylinder is swingably connected to the top horizontal frame 11 or the vertical frame 10. If driven by the cylinder and the piston, the operating table 2 can be rotated around the rotation axis, so that the inclination angle of the operating table 2 can be adjusted as needed.

[0029] In this embodiment, a hollow portion 22 is provided on the operating table 2, and the shape of the hollow portion 22 can be circular, elliptical or rectangular. A head support frame 4 and a limb fixing component 6 are provided on the operating table 2. The head support frame 4 is used to fix the head of the mouse, and the limb fixing component 6 is used to fix the limbs of the mouse. In order to fix mice of different sizes, preferably, the height of the head support frame 4 is adjustable, and the position of the limb fixing component 6 can also be adjusted as needed. For example, the limb fixing component 6 includes four fixing parts 61, and two horizontal slide grooves are provided on the operating table 2, and two fixing parts 61 are provided in each horizontal slide groove. In this way, when in use, the head support frame 4 can be adjusted to a suitable height, and the four fixing parts 61 can be adjusted to a suitable position to fix the mouse.

[0030] The utility model provides a mouse placement rack for experiments, comprising a bottom support frame 1, an operating table 2 arranged on the bottom support frame 1, and a rotating drive mechanism 3, the rotating drive mechanism 3 comprising a driving unit 30 and a telescopic rod 31, a hollow portion 22 is arranged on the operating table 2, a head support frame 4 is arranged on one side of the hollow portion 22 of the operating table 2, a limb fixing component 6 is arranged on the operating table 2, the limb fixing component 6 does not include a plurality of adjustable fixing members 61, so that when in use, the position of the fixing member 61 can be adjusted as needed, so that the fixing member 61 and the head support frame 4 can fix and restrict mice of different sizes, and the operating table 2 can be rotatably installed on the bottom support frame 1, and the angle of the operating table 2 can be adjusted by the rotating drive mechanism 3, so as to change the inclination angle of the mouse and facilitate surgical operations.

[0031] In this embodiment, preferably, the head support frame 4 includes a lower frame body 40 and an upper frame body 41, the lower frame body 40 includes a lower support rod 400 and a lower support plate 401 arranged on the lower support rod 400, the lower support plate 401 is provided with a lower arc-shaped limiting groove 402, there are at least two lower support rods 400, and the lower support rod 400 can be set to be adjustable in length, such that the lower support rod 400 includes a fixed rod and a movable rod, the fixed rod is fixedly installed on the operating table 2, and a movement channel for the movable rod to move up and down is provided on the fixed rod, the upper end of the movable rod is fixedly connected to the lower support plate 401, a plurality of locking holes are provided on the movable rod, and a locking bolt is provided on the movable rod, when the movable rod moves to a suitable height along the movement channel, the locking bolt is rotated into the locking hole accordingly to fix the movable rod, so that the lower support plate 401 can be adjusted to a suitable height.

[0032] In this embodiment, preferably, the upper frame 41 includes an upper support plate 410 and a guide rod 411. There are two guide rods 411, and the two guide rods 411 are fixedly mounted on the lower support plate 401. The upper support plate 410 is adjustably mounted on the guide rod 411. The upper support plate 410 is provided with an upper arc-shaped limiting groove 412. The upper arc-shaped limiting groove 412 and the lower arc-shaped limiting groove 402 together form a circular limiting cavity 42. The upper support plate 410 is provided with two through holes for the guide rod 411 to pass through. In this way, the upper support plate 410 can move up and down along the guide rod 411 to adjust the size of the circular limiting cavity 42, so that the circular limiting cavity 42 is consistent with the size of the mouse neck or head, thereby fixing the mouse head or neck.

[0033] In this embodiment, preferably, a top fixing plate 43 is provided on the top of the guide rod 411, and a threaded hole is provided on the top fixing plate 43. A threaded rod 430 is rotatably provided in the threaded hole. The rotation of the threaded rod 430 can drive the upper support plate 410 to move along the guide rod 411. The elastic member 44 is sleeved on the guide rod 411. The elastic member 44 blocks the movement of the upper support plate 410 along the guide rod 411. The lower end of the threaded rod 430 abuts against the upper support plate 410. In this way, when the threaded rod 430 is rotated downward, the lower end of the threaded rod 430 will contact the upper support plate 410. The support plate 410 is pressed so that the upper support plate 410 moves downward along the guide rod 411, so that the size of the circular limiting cavity 42 becomes smaller until the head or neck of the mouse is fixed. During this process, the elastic member 44 is pressed and has elasticity. Conversely, when the threaded rod 430 is rotated upward, the pressure of the threaded rod 430 on the upper support plate 410 disappears. In this way, under the action of the elastic member 44, the upper support plate 410 can move upward, so that the size of the circular limiting cavity 42 becomes larger. At this time, the mouse can be removed or the mouse's head can be placed in the circular limiting cavity 42.

[0034] In this embodiment, preferably, a strip bottom beam 5 is provided on the operating table 2, a strip slide groove 50 is provided on the strip bottom beam 5, the fixing member 61 includes a sliding seat 63 and a fixing structure 630 arranged on the sliding seat 63, the sliding seat 63 is slidably connected to the strip slide groove 50, and strip limiting grooves are respectively provided on both side walls of the strip slide groove 50, and side limiting strips 631 are provided on both sides of the sliding seat 63, and the side limiting strips 631 are slidably connected in the strip limiting grooves, and the fixing structure 630 can be a fixing rope or a fixing clamp, which is a commonly used structure in the prior art and will not be repeated. The sliding seat 63 slides along the strip slide groove 50 to adjust its position, so that the fixing member 61 can be adjusted to a suitable position, thereby achieving the fixation of mice of different sizes.

[0035] In this embodiment, preferably, a locking member 62 is further included, which is arranged on the sliding seat 63. The strip slide 50 is provided with a locking portion along the length direction. The locking member 62 can fix the sliding seat 63 at any position of the strip slide 50; the locking portion can be a locking tooth groove 51 arranged at the bottom of the strip slide, and there are multiple locking tooth grooves 51. The multiple locking tooth grooves 51 are sequentially spaced along the length direction of the strip slide 50. The locking member 62 includes a locking block 64 and a locking screw 65. The bottom of the locking block 64 is provided with a locking serration 641 corresponding to the locking tooth groove 51. The bottom of the sliding seat 63 is provided with an open cavity 632. The locking block 64 The sliding is restricted in the open cavity 632, and the locking block 64 moves up and down along the open cavity 632 and has a collection state in the open cavity 632 and a locking state extending from the open cavity 632. In the locked state, the locking block 64 extends from the open cavity 632, so that the locking serrations 641 on the locking block 64 are correspondingly engaged with the locking tooth groove 51, thereby locking the sliding seat 63 in the strip sliding. In the collection state, the locking block 64 is collected in the open cavity 632, and the locking serrations 641 on the locking block 64 are separated from the locking tooth groove 51, so that the sliding seat 63 can move along the strip slide groove 50 to adjust its position. A locking channel 633 is provided on the sliding seat 63, the lower end of the locking channel 633 is connected to the opening cavity 632, the upper end of the locking channel 633 passes through the sliding seat 63, a threaded portion is provided in the locking channel 633, the locking screw 65 is rotatably connected in the locking channel 633, a connecting hole is provided at the upper end of the locking block 64, the lower end of the locking screw 65 is rotatably connected in the connecting hole, so that the rotation of the locking screw 65 can correspondingly drive the locking block 64 to move up and down along the opening cavity 632, thereby switching the locking block 64 between a locked state and a stored state.

[0036] The above only describes some exemplary embodiments of the present invention by way of illustration. It is undoubted that those skilled in the art can modify the described embodiments in various ways without departing from the spirit and scope of the present invention. Therefore, the above drawings and descriptions are illustrative in nature and should not be construed as limiting the scope of protection of the claims of the present invention.

Claims

1. A mouse placement rack for an experiment, comprising a bottom support frame and an operating table arranged on the bottom support frame, characterized in that: It also includes a rotation drive mechanism, the rotation drive mechanism includes a drive unit and a telescopic rod, the operating table includes a rotation side and a drive side, the rotation side is rotatably connected to one side of the bottom support frame, one end of the telescopic rod is connected to the drive side, and the operating table is driven by the drive unit and the telescopic rod to rotate to change the tilt angle; The operating table is provided with a hollow portion, and a head support frame is provided on one side of the hollow portion. The operating table is also provided with a limb fixing assembly, and the limb fixing assembly includes multiple fixing parts, and the multiple fixing parts can move along the preset direction of the operating table to adjust their positions.

2. The experimental mouse placement rack according to claim 1, characterized in that: The head support frame comprises a lower frame body and an upper frame body, the lower frame body comprises a lower support rod and a lower support plate arranged on the lower support rod, and the lower support plate is provided with a lower arc-shaped limiting groove.

3. The experimental mouse placement rack according to claim 2, characterized in that: The upper frame includes an upper support plate and guide rods. There are two guide rods, and the two guide rods are fixedly mounted on the lower support plate. The upper support plate is adjustably mounted on the guide rods.

4. The experimental mouse placement rack according to claim 3, characterized in that: An upper arc-shaped limiting groove is arranged on the upper supporting plate, and the upper arc-shaped limiting groove and the lower arc-shaped limiting groove together form an adjustable circular limiting cavity.

5. The experimental mouse placement rack according to claim 4, characterized in that: A top fixing plate is arranged on the top of the guide rod, a threaded hole is arranged on the top fixing plate, a threaded rod is rotatably arranged in the threaded hole, and the rotation of the threaded rod can drive the upper support plate to move along the guide rod.

6. The experimental mouse placement rack according to claim 5, characterized in that: It also includes an elastic member, which is sleeved on the guide rod, and the elastic member blocks the movement of the upper support plate along the guide rod downward.

7. The experimental mouse placement rack according to claim 1, characterized in that: The operating table is provided with a strip bottom beam, the strip bottom beam is provided with a strip slide groove, the fixing member comprises a sliding seat and a fixing structure arranged on the sliding seat, and the sliding seat is slidably connected to the strip slide groove.

8. The experimental mouse placement rack according to claim 7, characterized in that: It also includes a locking piece, which is arranged on the sliding seat. The strip-shaped slide groove is provided with a locking portion along the length direction. The locking piece can fix the sliding seat at any position of the strip-shaped slide groove.

Citation Information

Patent Citations

  • Adjustable white mouse rabbit mount

    CN204744492U