Heparin sodium precipitation device

Abstract

The utility model provides a heparin sodium precipitation device which comprises a tank body, a stirring mechanism is arranged in the tank body through a servo motor, the stirring mechanism comprises a rotating rod, a stirring paddle and blades, a sealing mechanism is arranged at the bottom end of the inner side of the tank body, and the sealing mechanism comprises a fixing table. The collecting cylinder is installed at the bottom end of the tank body through the bolt, the adjusting plate is driven through the hand wheel and the screw rod, the adjusting plate is moved away from the through hole, heparin sodium sediment and liquid can be conveniently discharged into the collecting cylinder at the same time, the heparin sodium sediment can be filtered through the filtering holes in the top end of the collecting cylinder, and the liquid is discharged through the liquid discharging pipe. The heparin sodium precipitate is left in the collecting cylinder, so that the heparin sodium can be collected while the liquid and the heparin sodium precipitate are discharged, the operation is simple, and the practicability is high; through the servo motor, the rotating rod, the stirring paddle and the blades, the collected mixed liquid of the eluent and the alcohol can be conveniently stirred.

Description

Technical Field

[0001] The utility model relates to the technical field of sodium heparin precipitation, in particular to a sodium heparin precipitation device. Background Art

[0002] Heparin sodium is an anticoagulant. Heparin sodium is mainly extracted from the small intestinal mucosa of pigs and sheep and bovine lungs, and the content is highest in the pig small intestinal mucosa. The extraction process of heparin sodium includes raw material processing, heating enzymatic hydrolysis, cooling adsorption, elution, precipitation and drying, among which a precipitation device is required during the precipitation process.

[0003] The Chinese utility model patent with publication number CN218529893U proposes a precipitation device for producing sodium heparin, including a tank body, a feed pipe is fixedly installed on the top of the tank body, a liquid outlet pipe is installed on the outside of the tank body, a first solenoid valve is installed on the outside of the liquid outlet pipe, and a discharge pipe is fixedly installed on the bottom of the tank body, and a second solenoid valve is installed on the outside of the discharge pipe.

[0004] After the sodium heparin precipitation is completed, the above technical solution discharges the material through the second solenoid valve and the discharge pipe, but there is no filtering and collecting mechanism at the bottom of the device. After the liquid and the sodium heparin precipitation are discharged together, the sodium heparin needs to be filtered by a filtering device. The sodium heparin processing efficiency is low, and it cannot be filtered and collected at the same time as it is discharged, so it is of low practicality.

[0005] To this end, the utility model provides a heparin sodium precipitation device. Utility Model Content

[0006] In view of the deficiencies in the prior art, the utility model aims to provide a sodium heparin precipitation device to solve the problems raised in the above-mentioned background technology. The utility model can collect sodium heparin while discharging liquid and sodium heparin precipitation through a collecting tube and a filter hole at the top of the collecting tube, thereby improving the processing and production efficiency of sodium heparin, being simple to operate and highly practical.

[0007] In order to achieve the above-mentioned purpose, the utility model is realized through the following technical scheme: a heparin sodium precipitation device, comprising a tank body, the interior of the tank body is provided with a stirring mechanism through a servo motor, the stirring mechanism comprises a rotating rod, a stirring paddle and blades, a closing mechanism is provided at the bottom end of the inner side of the tank body, the closing mechanism comprises a fixing platform, the fixing platform is fixedly installed at the bottom of the inner side of the tank body, an adjusting mechanism is provided at the bottom end of the fixing platform, a through hole is opened at the center position of the fixing platform, and a collecting cylinder is installed at the bottom of the closing mechanism through bolts, and the bolts are threadedly installed on both sides of the bottom of the tank body.

[0008] Furthermore, the top end of the collecting tube is plugged and installed inside the tank body, the top end of the collecting tube is arranged at the bottom of the through hole, and a sealing ring is arranged between the collecting tube and the tank body.

[0009] Furthermore, a filter hole is provided inside the top of the collecting tube, and a drain pipe is fixedly and obliquely provided on one side of the bottom end of the tank body corresponding to the collecting tube.

[0010] Furthermore, the adjustment mechanism comprises a slide groove, which is arranged at a position corresponding to the through hole on one side of the bottom end of the fixed platform, and an adjustment plate is slidably installed inside the slide groove.

[0011] Furthermore, a screw hole is provided inside the adjusting plate, and a screw rod is screwed and installed inside the screw hole.

[0012] Furthermore, the screw is rotationally limited and installed inside the bottom end of the tank body, a hand wheel is fixedly provided on the outer end of the screw, and a rubber ring is fixedly installed on the outer side of the through hole corresponding to the top of the slide groove.

[0013] Furthermore, the top end of the rotating rod is fixedly connected to the output shaft of the servo motor, the stirring paddle is fixedly mounted on the rotating rod, and the blade is fixedly mounted on the bottom end of the rotating rod.

[0014] Furthermore, a first feeding port and a second feeding port are respectively arranged on both sides of the top of the tank body corresponding to the servo motor, and three legs are fixedly installed on the bottom of the tank body.

[0015] The beneficial effects of the utility model are as follows: the sodium heparin precipitation device of the utility model is used to install the collecting tube on the bottom end of the tank body by bolts, and the adjusting plate is driven by the hand wheel and the screw rod to remove the adjusting plate from the through hole, so that the sodium heparin precipitation and the liquid are conveniently discharged into the interior of the collecting tube at the same time, and the sodium heparin precipitation can be filtered through the filter hole at the top of the collecting tube, and the liquid is discharged through the liquid discharge pipe, while the sodium heparin precipitation remains in the collecting tube, and the sodium heparin can be collected while the liquid and the sodium heparin precipitation are discharged, so that the processing and production efficiency of the sodium heparin can be improved, the operation is simple, and the practicability is high; the collected mixed solution of the eluent and the alcohol is conveniently stirred by the servo motor, the rotating rod, the stirring paddle and the blade. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 This is a structural diagram of a sodium heparin precipitation device of the utility model;

[0017] Figure 2 This is a cross-sectional view of a sodium heparin precipitation device of the utility model;

[0018] Figure 3 This utility model is a heparin sodium precipitation device Figure 2 Enlarged view of point A in the middle;

[0019] Figure 4 This is a structural diagram of a collection tube of a heparin sodium precipitation device of the utility model;

[0020] Figure 5 This is a structural diagram of a closed mechanism of a sodium heparin precipitation device of the utility model;

[0021] In the figure: 1. tank body; 2. first feeding port; 3. servo motor; 4. second feeding port; 5. collecting tube; 6. supporting legs; 7. drain pipe; 8. adjusting mechanism; 9. rotating rod; 10. stirring paddle; 11. fixing platform; 12. screw; 13. bolt; 14. blade; 15. adjusting plate; 16. screw hole; 17. filter hole. DETAILED DESCRIPTION

[0022] In order to make the technical means, creative features, objectives and effects achieved by the present invention easy to understand, the present invention is further described below in conjunction with specific implementation methods.

[0023] See also Figures 1 to 5 The utility model provides a technical solution: a heparin sodium precipitation device, comprising a tank body 1, wherein a stirring mechanism is arranged inside the tank body 1 through a servo motor 3, wherein the stirring mechanism comprises a rotating rod 9, a stirring paddle 10 and a blade 14, wherein a closing mechanism is arranged at the bottom end of the inner side of the tank body 1, wherein the closing mechanism comprises a fixing platform 11, wherein the fixing platform 11 is fixedly mounted at the bottom of the inner side of the tank body 1, wherein an adjusting mechanism 8 is arranged at the bottom end of the fixing platform 11, wherein a through hole is provided at the center position of the fixing platform 11, wherein a collecting cylinder 5 is installed at the bottom of the closing mechanism through bolts 13, wherein the bolts 13 are screwed and mounted on both sides of the bottom of the tank body 1, wherein the heparin sodium precipitate can be collected and discharged through the setting of the collecting cylinder 5, thereby improving the processing and production efficiency of the heparin sodium.

[0024] In this embodiment, the top end of the collecting tube 5 is plugged and installed inside the tank body 1, and the top end of the collecting tube 5 is arranged at the bottom of the through hole. A sealing ring is arranged between the collecting tube 5 and the tank body 1, and a filter hole 17 is arranged inside the top end of the collecting tube 5. A drain pipe 7 is fixedly and obliquely arranged on one side of the bottom end of the tank body 1 corresponding to the collecting tube 5. When the mixed liquid and the precipitate are discharged, the liquid can be discharged through the filter hole 17 and the drain pipe 7, and the heparin sodium precipitate remains in the collecting tube 5, which is convenient for collecting the heparin sodium precipitate.

[0025] In this embodiment, the adjustment mechanism 8 includes a slide groove, which is opened on one side of the bottom end of the fixed platform 11 at a position corresponding to the through hole. An adjustment plate 15 is slidably installed inside the slide groove. A screw hole 16 is opened inside the adjustment plate 15. A screw 12 is screwed and installed inside the screw hole 16. The screw 12 is limited and rotatably installed inside the bottom end of the tank body 1. A hand wheel is fixedly provided at the outer end of the screw 12. A rubber ring is fixedly installed on the top of the slide groove corresponding to the outer side of the through hole. The rubber ring can increase the sealing between the adjustment plate 15 and the through hole, and can prevent the mixed liquid from leaking during stirring. The adjustment plate 15 can be adjusted by the hand wheel and the screw 12, so that the mixed liquid and the heparin sodium precipitate can be discharged downward after the precipitation is completed, thereby facilitating the subsequent collection of the heparin sodium precipitate.

[0026] In this embodiment, the top end of the rotating rod 9 is fixedly connected to the output shaft of the servo motor 3, the stirring paddle 10 is fixedly installed on the rotating rod 9, and the blade 14 is fixedly installed on the bottom end of the rotating rod 9. The servo motor 3 drives the rotating rod 9 to rotate inside the tank body 1. The rotating rod 9 stirs the mixed liquid through the stirring paddle 10 and the blade 14 to facilitate the reaction between the eluent and the alcohol to generate heparin sodium precipitate.

[0027] In this embodiment, a first feeding port 2 and a second feeding port 4 are respectively provided on both sides of the top of the tank body 1 corresponding to the servo motor 3, and three legs 6 are fixedly installed on the bottom of the tank body 1. The first feeding port 2 and the second feeding port 4 are convenient for adding eluent and alcohol to the interior of the tank body 1, respectively, to facilitate the subsequent production of heparin sodium.

[0028] When using the sodium heparin precipitation device, the collecting tube 5 is inserted into the bottom end of the tank body 1 and fixed by the bolt 13. The top of the collecting tube 5 contacts the bottom of the fixing platform 11. The hand wheel is turned, and the hand wheel drives the adjusting plate 15 to move inside the slide groove through the screw 12, so that the adjusting plate 15 is blocked inside the through hole, and the through hole is conveniently closed by the rubber ring. The eluent and alcohol are added to the inside of the tank body 1 through the first feeding port 2 and the second feeding port 4, respectively. The servo motor 3 is started, and the servo motor 3 drives the stirring paddle 10 and the blade 14 inside the tank body 1 through the rotating rod 9. Rotate to facilitate stirring of the eluent and alcohol. After stirring, let it stand for 10-12 hours. Drive the adjusting plate 15 through the hand wheel and the screw 12 to remove the adjusting plate 15 from the through hole, so that the sodium heparin precipitate and the liquid are discharged into the interior of the collecting tube 5 at the same time. The sodium heparin precipitate can be filtered through the filter hole 17 at the top of the collecting tube 5. The mixed liquid enters the interior of the bottom end of the tank body 1 through the filter hole 17 and is discharged through the drain pipe 7, while the sodium heparin precipitate remains in the collecting tube 5. The sodium heparin can be collected while the liquid and the sodium heparin precipitate are discharged. The operation is simple and the practicability is high.

[0029] In addition, it should be understood that although the present specification is described according to implementation modes, not every implementation mode contains only one independent technical solution. This description of the specification is only for the sake of clarity. Those skilled in the art should regard the specification as a whole. The technical solutions in each embodiment may also be appropriately combined to form other implementation modes that can be understood by those skilled in the art.

Claims

1. A sodium heparin precipitation device, comprising a tank (1), characterized in that: The tank body (1) is provided with a stirring mechanism inside through a servo motor (3), the stirring mechanism comprising a rotating rod (9), a stirring paddle (10) and a blade (14); a closing mechanism is provided at the bottom end of the inner side of the tank body (1); the closing mechanism comprises a fixing platform (11), the fixing platform (11) is fixedly mounted on the bottom of the inner side of the tank body (1); an adjusting mechanism (8) is provided at the bottom end of the fixing platform (11); a through hole is provided at the center of the fixing platform (11); a collecting cylinder (5) is installed at the bottom of the closing mechanism through bolts (13), the bolts (13) are screwed on both sides of the bottom of the tank body (1); a filter hole (17) is provided inside the top end of the collecting cylinder (5); and a liquid discharge pipe (7) is fixedly arranged at a side of the bottom end of the tank body (1) corresponding to the collecting cylinder (5) in an inclined manner.

2. A heparin sodium precipitation device according to claim 1, characterized in that: The top end of the collecting tube (5) is plugged and installed inside the tank body (1), the top end of the collecting tube (5) is arranged at the bottom of the through hole, and a sealing ring is arranged between the collecting tube (5) and the tank body (1).

3. A heparin sodium precipitation device according to claim 1, characterized in that: The adjustment mechanism (8) comprises a slide groove, the slide groove is provided at a position corresponding to a through hole on one side of the bottom end of the fixed platform (11), and an adjustment plate (15) is slidably mounted inside the slide groove.

4. A heparin sodium precipitation device according to claim 3, characterized in that: A screw hole (16) is provided inside the adjustment plate (15), and a screw rod (12) is threadedly installed inside the screw hole (16).

5. A heparin sodium precipitation device according to claim 4, characterized in that: The screw rod (12) is mounted inside the bottom end of the tank body (1) for limited rotation, a hand wheel is fixedly provided on the outer end of the screw rod (12), and a rubber ring is fixedly installed on the outer side of the through hole corresponding to the top of the slide groove.

6. A heparin sodium precipitation device according to claim 1, characterized in that: The top end of the rotating rod (9) is fixedly connected to the output shaft of the servo motor (3), the stirring paddle (10) is fixedly mounted on the rotating rod (9), and the blade (14) is fixedly mounted on the bottom end of the rotating rod (9).

7. A heparin sodium precipitation device according to claim 1, characterized in that: A first feeding port (2) and a second feeding port (4) are respectively arranged on both sides of the top of the tank body (1) corresponding to the servo motor (3), and three supporting legs (6) are fixedly mounted on the bottom of the tank body (1).

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