Reagent self-mixing device

The reagent self-mixing device addresses cross-contamination and cost issues in single-molecule fluorescence immunoassay analyzers by using a gear-driven turntable for self-mixing, ensuring efficient and stable reagent uniformity without separate stirring mechanisms.

CN222287078UActive Publication Date: 2025-01-03HANGZHOU GETOTEC CO LTD
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Patent Information

Application Number
CN202323653072.X
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2023-12-30
Publication Date
2025-01-03
Estimated Expiration
2033-12-30

AI Technical Summary

Technical Problem

Existing reagent mixing devices in single-molecule fluorescence immunoassay analyzers face issues of cross-contamination and high cost due to separate stirring mechanisms, which occupy significant space and increase machine costs.

Method used

A reagent self-mixing device utilizing a motor-driven turntable with main and driven gears to rotate reagent bottles, achieving self-mixing without a stirring needle, and incorporating inward protrusions for improved mixing efficiency.

Benefits of technology

The device ensures uniform reagent mixing without cross-contamination and reduces space and cost by eliminating the need for separate stirring mechanisms, while enhancing mixing efficiency and stability.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model provides a reagent self-mixing device which comprises a motor, a turntable and a plurality of reagent bottles, the plurality of reagent bottles are arranged on the turntable, and the turntable is fixed on a rotating shaft of the motor; the main gear is arranged around the rotating shaft and is arranged on the fixed seat; the first group of bearing seats are respectively arranged at the upper ends of the first group of rotating shafts and are used for bearing the reagent bottles, and the first group of rotating shafts penetrate through the turntable; the first group of driven gears are respectively fixed at the lower ends of the first group of rotating shafts and are meshed with the main gear; and when the motor drives the turntable to rotate, the reagent bottles on the first group of bearing seats revolve around the main gear and rotate. The mixing device has the advantages of uniform mixing and the like.
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Description

Technical Field

[0001] The utility model relates to single molecule detection, in particular to a reagent self-mixing device. Background Art

[0002] The single-molecule fluorescence immunoassay analyzer uses immunodiagnostic technology to detect neural markers, myocardial markers, inflammatory markers, tumor markers, infection markers, etc. It detects single molecules through capillary flow technology to achieve sample trace concentration detection. The instrument mainly includes a reagent module, an incubation module, a magnetic separation module, a sample addition module, etc. The reagent module is a device for storing reagents in the single-molecule fluorescence immunoassay analyzer. In order to obtain uniform reagents, the reagents stored in the reagent module need to be kept in a mixed state so that the reaction reagents added in the subsequent reaction are uniform. Therefore, a device that can mix multiple reagent bottles at the same time is required in the reagent module.

[0003] Reagent bottle mixing devices are often used in medical testing equipment, such as chemiluminescence equipment. Domestic and foreign manufacturers mostly use separate stirring to mix reagents in order to solve the problem of reagent bottle mixing in the instrument. This often leads to two problems:

[0004] 1. When different reagents are mixed by separate stirring, there is a risk of cross contamination of different reagents.

[0005] 2. A stirring needle assembly is separately provided in the whole machine, which occupies a large amount of space and is expensive, greatly increasing the cost of the whole machine. Summary of the invention

[0006] In order to solve the deficiencies in the above-mentioned prior art solutions, the utility model provides a reagent self-mixing device.

[0007] The purpose of this utility model is achieved through the following technical solutions:

[0008] The reagent self-mixing device comprises a motor, a turntable and a plurality of reagent bottles, wherein the plurality of reagent bottles are arranged on the turntable, and the turntable is fixed on the rotating shaft of the motor; the reagent self-mixing device also comprises:

[0009] A main gear and a fixed seat, wherein the main gear is arranged around the rotating shaft and is arranged on the fixed seat;

[0010] A first group of bearing seats, which are respectively arranged at the upper ends of the first group of rotating shafts and are used to bear the reagent bottles, and the first group of rotating shafts passes through the turntable;

[0011] The first group of driven gears are respectively fixed at the lower end of the first group of rotating shafts and mesh with the main gears; when the motor drives the turntable to rotate, the reagent bottles on the first group of supporting seats revolve around the main gears and rotate on their own axes.

[0012] Compared with the prior art, the utility model has the following beneficial effects:

[0013] 1. Self-mixing is achieved;

[0014] By using a fixed main gear and a driven gear meshing with the main gear arranged on the lower side of the turntable, when the turntable rotates, the driven gear revolves and rotates around the main gear, thereby driving the reagent bottle to revolve and rotate around the main gear, thereby achieving self-mixing of the reagent, without the need for a stirring needle, and avoiding the cross contamination problem existing in the prior art;

[0015] 2. Good mixing effect;

[0016] The inner wall of the reagent bottle is provided with an inward protrusion extending in the up-down direction, so that the reagent is fully mixed during the rotation of the reagent bottle and bubbles are avoided during the mixing process;

[0017] 3. High mixing efficiency;

[0018] The turntable is provided with multiple circles of reagent bottles surrounding the main gear, and the self-mixing efficiency of absorbing reagents in multiple reagent bottles is high. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] The disclosure of the present invention will become easier to understand with reference to the accompanying drawings. It is easy for those skilled in the art to understand that these drawings are only used to illustrate the technical solution of the present invention and are not intended to limit the scope of protection of the present invention. In the drawings:

[0020] Figure 1 This is a schematic diagram of the structure of a reagent self-mixing device according to an embodiment of the utility model;

[0021] Figure 2 It is a bottom view schematic diagram of a turntable according to an embodiment of the utility model;

[0022] Figure 3 It is a structural schematic diagram of a driven gear and a reagent bottle according to an embodiment of the utility model;

[0023] Figure 4 It is a schematic structural diagram of a reagent bottle according to an embodiment of the utility model. DETAILED DESCRIPTION

[0024] Figure 1-Figure 4The following description describes optional specific embodiments of the present invention to teach those skilled in the art how to implement and reproduce the present invention. In order to teach the technical solution of the present invention, some conventional aspects have been simplified or omitted. Those skilled in the art should understand that variations or substitutions derived from these specific embodiments will be within the scope of the present invention. Those skilled in the art should understand that the following features can be combined in various ways to form multiple variations of the present invention. Thus, the present invention is not limited to the following optional specific embodiments, but is only limited by the claims and their equivalents.

[0025] Example 1

[0026] The reagent self-mixing device of the utility model embodiment is as follows Figure 1 As shown, the reagent self-mixing device comprises:

[0027] A motor and a turntable 31, wherein the turntable 31 is fixed on the rotating shaft 11 of the motor;

[0028] A main gear 21 and a fixing seat 51, wherein the main gear 21 is arranged around the rotating shaft 11 and is arranged on the fixing seat 51;

[0029] The first group of bearing seats 41, such as Figure 2-3 As shown, the first group of bearing seats 41 are respectively arranged at the upper ends of the first group of rotating shafts and are used to bear the reagent bottles 61. The first group of rotating shafts passes through the rotating disk 31;

[0030] The first group of driven gears 22 are respectively fixed at the lower end of the first group of rotating shafts and mesh with the main gear 21; when the motor drives the turntable 31 to rotate, the reagent bottle 61 on the first group of supporting seats 41 revolves around the main gear 21 and rotates on its own axis.

[0031] In order to improve the mixing efficiency, further, Figure 1 , Figure 2 As shown, the reagent self-mixing device also includes:

[0032] A second group of bearing seats 42, which are respectively disposed at the upper ends of the second group of rotating shafts and are used to bear the reagent bottles 61, and the second group of rotating shafts pass through the rotating disk 31;

[0033] The second group of driven gears 23 are respectively fixed at the lower end of the second group of rotating shafts and mesh with the first group of driven gears 22; when the motor drives the turntable 31 to rotate, the reagent bottle 61 on the second group of supporting seats 42 revolves around the main gear 21 and rotates on its own axis.

[0034] In order to improve the uniformity of self-mixing, further, as Figure 4As shown, the inner wall of the reagent bottle has a plurality of inward protrusions extending in the up-down direction.

[0035] In order to improve the stability of the rotation of the turntable, further, the first group of driven gears evenly surrounds the main gear, and the second group of driven gears evenly surrounds the main gear.

[0036] In order to improve safety, the reagent self-mixing device further includes:

[0037] A protective member 52 surrounds the turntable 31 and the reagent bottle 61 , and a lower end of the protective member 52 is fixed on the fixing seat 51 .

[0038] Example 2

[0039] According to the embodiment of the utility model, the reagent self-mixing device is used in a single-molecule fluorescence immunoassay analyzer.

[0040] In this application example, Figure 1 As shown, the turntable 31 is fixed on the motor shaft 11, and the main gear 21 is arranged outside the shaft 11 and fixed on the fixing seat 51. The cylindrical protection member 52 surrounds the turntable 31 and the reagent bottle 61, and the lower end is fixed on the fixing seat 51.

[0041] like Figure 2 As shown, the first group of bearing seats 41 is fixed to the upper end of the first group of rotating shafts, the first group of rotating shafts pass through the bearings, and the bearings are fixed on the rotating disk 31. The second group of bearing seats 42 is fixed to the upper end of the second group of rotating shafts, the second group of rotating shafts pass through the bearings, and the bearings are fixed on the rotating disk 31.

[0042] like Figure 3 As shown, the first set of driven gears 22 is installed at the lower end of the first set of rotating shafts, meshing with the main gear 21 and evenly surrounding the main gear 21. The second set of driven gears 23 is installed at the lower end of the second set of rotating shafts, meshing with the first set of driven gears 22 and evenly surrounding the main gear 21.

[0043] like Figure 4 As shown, the inner wall of the reagent bottle 61 has a plurality of inward protrusions 62 extending in the up-down direction.

[0044] The working mode of the reagent self-mixing device of this embodiment is:

[0045] The motor drives the turntable 31 to rotate, and the first set of driven gears 22 revolve around the main gear and rotate on its own, thereby driving the revolution and rotation of the reagent bottle (around the main gear 21) on the first bearing seat 41, so that the reagent achieves self-mixing, and the inward protrusion 62 further improves the self-mixing effect;

[0046] At the same time, the first group of driven gears 22 drives the second group of driven gears 23 to rotate, driving the revolution and rotation of the reagent bottle 61 on the second supporting seat 42, so that the reagent achieves self-mixing, and the inward protrusion 62 further improves the self-mixing effect.

Claims

1. A reagent self-mixing device, comprising a motor, a turntable and a plurality of reagent bottles, wherein the plurality of reagent bottles are arranged on the turntable, and the turntable is fixed on the rotating shaft of the motor; characterized in that: The reagent self-mixing device also includes: A main gear and a fixed seat, wherein the main gear is arranged around the rotating shaft and is arranged on the fixed seat; A first group of bearing seats, which are respectively arranged at the upper ends of the first group of rotating shafts and are used to bear the reagent bottles, and the first group of rotating shafts passes through the turntable; The first group of driven gears are respectively fixed at the lower end of the first group of rotating shafts and mesh with the main gears; when the motor drives the turntable to rotate, the reagent bottles on the first group of supporting seats revolve around the main gears and rotate on their own axes.

2. The reagent self-mixing device according to claim 1, characterized in that: The reagent self-mixing device also includes: A second group of bearing seats, which are respectively arranged at the upper ends of the second group of rotating shafts and are used to bear the reagent bottles, and the second group of rotating shafts pass through the turntable; The second group of driven gears are respectively fixed at the lower ends of the second group of rotating shafts and mesh with the first group of driven gears; when the motor drives the turntable to rotate, the reagent bottles on the second group of supporting seats revolve around the main gears and rotate on their own axes.

3. The reagent self-mixing device according to claim 1, characterized in that: The inner wall of the reagent bottle has a plurality of inward protrusions extending in the up-down direction.

4. The reagent self-mixing device according to claim 1, characterized in that: The first set of driven gears evenly surround the main gear.

5. The reagent self-mixing device according to claim 2, characterized in that: The second set of driven gears evenly surrounds the main gear.

6. The reagent self-mixing device according to claim 1, characterized in that: The reagent self-mixing device also includes: A protective member surrounds the turntable and the reagent bottle, and a lower end of the protective member is fixed on a fixing seat.