Human stem cell culture instrument
By designing a combined structure of a fixing frame and a sliding plate in a human stem cell culture instrument, the problem of difficult fixation and low efficiency of the culture dishes in the prior art is solved, and the stable fixation and orderly arrangement of multiple culture dishes are achieved, thereby improving the cells Efficiency of cultivation.
Patent Information
- Application Number
- CN202421427009.6
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-02
- Publication Date
- 2025-01-07
- Estimated Expiration
- 2034-12-02
AI Technical Summary
The existing human stem cell culture instruments are inefficient when culturing multiple dishes and the dishes are not easy to fix, resulting in shaking that is not conducive to cell culture.
A human stem cell culture instrument was designed, with multiple parallel fixing frames and sliding plates installed inside, and connected by guide rods and springs to form a placement groove with a constant spacing to ensure the stable fixation and orderly arrangement of the culture dish.
The orderly arrangement and stable fixation of multiple culture dishes are achieved, which improves the culture efficiency and stability of human stem cells and facilitates batch culture.
Smart Images

Figure CN222313188U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of cell culture, in particular to a human stem cell culture instrument. Background Art
[0002] The "stem" in stem cell (SC) is translated from the English word "stem", which means "stem", "dry" and "origin". The function of stem cell population is to control and maintain cell regeneration. Generally speaking, there is an intermediate progenitor cell population called "committed progenitor cells" between stem cells and their terminally differentiated daughter cells, which have limited expansion capacity and restricted differentiation potential. The function of these cell populations is to increase the number of differentiated cells produced after each division of stem cells. Stem cells have the ability to self-renew, but the division of stem cells is actually relatively asymmetric. Human stem cells have extremely broad application prospects in the fields of cell repair, developmental biology, pharmacology, etc. in life sciences.
[0003] Human stem cells are cultured using a culture instrument. However, existing human stem cell culture instruments are usually only able to culture human stem cells on a single culture dish, resulting in low culture efficiency. In addition, the culture dish used to culture human stem cells is not convenient to place inside the culture instrument and is prone to shaking inside. The culture dish cannot be well fixed, which is not conducive to the culture of human stem cells.
[0004] Therefore, those skilled in the art provide a human stem cell culture apparatus to solve the problems raised in the above background technology. Utility Model Content
[0005] The purpose of the utility model is to provide a human stem cell culture instrument to solve the problems raised in the above background technology.
[0006] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a human stem cell culture instrument, comprising a culture instrument body, a placement component for placing a culture dish installed inside the body, the placement component comprising a plurality of parallel fixed frames, the fixed frames are connected to the inner wall of the body through a pull-out component, and a plurality of fixed components for preventing the culture dish from shaking are installed on the top of the fixed frames; the fixed components comprise a plurality of sliding plates installed on the fixed frames, a plurality of notches are respectively provided on both sides of the sliding plates, the notches on adjacent sliding plates are arranged oppositely, the plurality of sliding plates are connected by two guide rods, and a placement groove for placing the culture dish is formed between the notches between the two sliding plates.
[0007] Preferably, a plurality of partitions are provided on the guide rod and between two adjacent sliding plates.
[0008] Preferably, the separator comprises a spring mounted on two sliding plates.
[0009] Preferably, limiting grooves are respectively provided on both sides of the sliding plate, a sleeve is connected between two opposite limiting grooves, and the sleeve is located between two adjacent limiting grooves.
[0010] Preferably, a positioning plate is provided at one end of the fixing frame, one of the sliding plates located at the end is fixedly connected to the positioning plate, and a shifting plate is provided on a sliding plate opposite to the positioning plate.
[0011] Preferably, a gusset plate is provided on the fixing frame, the gusset plate is arranged opposite to the positioning plate, and the gusset plate is clamped with the dial plate.
[0012] Preferably, the pull-out assembly comprises sliding blocks installed on both sides of the fixing frame, and a sliding groove is provided on the inner wall of the body.
[0013] Compared with the prior art, the beneficial effects of the utility model are:
[0014] 1. In the utility model, a fixing frame is provided, and a plurality of fixing frames are arranged at equal intervals inside the main body. A plurality of sliding plates are respectively installed on each fixing frame, and a plurality of placement grooves formed by notches are provided between the plurality of sliding plates. Culture dishes for culturing human stem cells can be respectively placed in different placement grooves, and a plurality of culture dishes can be orderly arranged inside the main body, which is convenient for culturing human stem cells.
[0015] 2. In the utility model, a partition is provided between adjacent sliding plates, the partition is composed of two springs, and the adjacent sliding plates are connected by a sleeve, so that the distance between two adjacent sliding plates can be made the same. During the sliding process of the sliding plate at one end, the distance between the adjacent sliding plates remains constant, which can facilitate the placement and fixation of multiple culture dishes. BRIEF DESCRIPTION OF THE DRAWINGS
[0016] Figure 1 It is a schematic diagram of the overall structure of the utility model;
[0017] Figure 2 It is a left view of the utility model.
[0018] Figure 3 For this utility model Figure 2 Three-dimensional cross-section view at AA in the middle.
[0019] Figure 4 For this utility model Figure 3 Enlarged view of point A in the middle.
[0020] Figure 5 For this utility model Figure 2 Three-dimensional cross-section view at the middle BB.
[0021] Figure 6 For the utility model Figure 5Enlarged view of point B in the middle.
[0022] In the figure: 1, body; 2, fixing frame; 3, sliding plate; 4, notch; 5, guide rod; 7, spring; 8, limit groove; 9, sleeve; 10, positioning plate; 11, dial plate; 12, buckle plate; 13, slider; 14, slide groove; 15, buffer pad. DETAILED DESCRIPTION
[0023] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.
[0024] See also Figure 1 to Figure 6 In an embodiment of the utility model, a human stem cell culture instrument comprises a culture instrument body 1, wherein a placement assembly for placing a culture dish is installed inside the body 1, wherein the placement assembly comprises a plurality of parallel fixed frames 2, wherein the fixed frames 2 are connected to the inner wall of the body 1 through a pull-out assembly, and a plurality of fixed assemblies for preventing the culture dish from shaking are installed on the top of the fixed frames 2; wherein the fixed assemblies comprise a plurality of sliding plates 3 installed on the fixed frames 2, wherein a plurality of notches 4 are respectively arranged on both sides of the sliding plates 3, wherein the notches 4 on adjacent sliding plates 3 are arranged opposite to each other, wherein the plurality of sliding plates 3 are connected by two guide rods 5, and a placement groove for placing the culture dish is formed between the notches 4 between two sliding plates 3.
[0025] The main body 1 is the shell of a human stem cell culture instrument commonly found on the market. The fixed frame 2 can be pulled in and out of the main body 1. The sliding plate 3 is installed on the fixed frame 2. The moving direction of the sliding plate 3 is perpendicular to the moving direction of the fixed frame 2. The notch 4 is provided on both sides of the sliding plate 3. The placement groove is formed by splicing two opposite notches 4. The culture dish used to culture human stem cells can be placed in the placement groove formed by the two notches 4. The culture dishes can be arranged in an orderly manner inside the main body 1. The guide rod 5 can guide the movement of multiple sliding plates 3. By moving the sliding plate 3, the culture dishes in multiple placement grooves can be fixed, which is convenient for the culture of human stem cells.
[0026] In one embodiment, specifically, a plurality of spacers are provided on the guide rod 5 and between two adjacent sliding plates 3, the spacers include springs 7 installed on the two sliding plates 3, limiting grooves 8 are provided on both sides of the sliding plates 3, a sleeve 9 is connected between two opposite limiting grooves 8, the sleeve 9 is located between two adjacent limiting grooves 8, the spacer is installed on the outside of the guide rod 5, the spacer is located between two adjacent sliding plates 3, can separate the two sliding plates 3 to avoid collision of the sliding plates 3, the spacer is composed of two springs 7, the limiting grooves 8 are opened on the sliding plate 3, the sleeve 9 is slidably installed between the two limiting grooves 8, can keep the distance difference between the two sliding plates 3 within a stable range, and can further guide the movement of the sliding plates 3.
[0027] Among them, a positioning plate 10 is provided at one end of the fixed frame 2, one of the sliding plates 3 located at the end is fixedly connected to the positioning plate 10, a sliding plate 11 is provided on the sliding plate 3 opposite to the positioning plate 10, and a buckle plate 12 is provided on the fixed frame 2, the buckle plate 12 is arranged opposite to the positioning plate 10, the buckle plate 12 is clamped with the dial plate 11, the positioning plate 10 is installed at one end of the fixed frame 2, and the buckle plate 12 is installed at the other end of the fixed frame 2, the sliding plate 3 at one end is fixedly connected to the positioning plate 10, and the sliding plate 3 at the other end can be connected to the positioning plate 10 through the dial plate 11 and the buckle plate 12, so that multiple placement slots are opened, which is convenient for placing culture dishes in batches on the fixed frame 2.
[0028] On the basis of the above embodiment, specifically, the pulling assembly includes sliders 13 installed on both sides of the fixing frame 2, a slide groove 14 is provided on the inner wall of the main body 1, the sliders 13 are fixedly connected to both sides of the fixing frame 2, the slide groove 14 is installed on the inner wall of the main body 1, and the sliders 13 are slidably connected to the slide groove 14 to facilitate the fixing frame 2 to enter and exit the main body 1.
[0029] When it is necessary to culture human stem cells, first pull the dial plate 11 to one end of the positioning plate 10 and buckle it onto the buckle plate 12. At this time, the spring 7 will be stretched. At this time, due to the setting of multiple partitions, the spacing between adjacent sliding plates 3 remains the same. At this time, the spacing between the two notches 4 will increase, which can facilitate the placement of the culture dish in the placement groove. Subsequently, multiple culture dishes containing human stem cells are placed in different placement grooves in turn. After the culture dishes on the same fixed frame 2 are placed, the dial plate 11 is removed from the buckle plate 12. At this time, the spring 7 retracts, and the adjacent sliding plates 3 will approach each other until all the culture dishes are fixed. Subsequently, the fixed frame 2 loaded with the culture dishes is steadily placed into the main body 1, the door of the main body 1 is closed, and the interior of the main body 1 is ventilated until the temperature and humidity inside the main body 1 are suitable for human stem cell culture.
[0030] In one embodiment, specifically, a buffer pad 15 is installed on one side of the notch 4, and the buffer pad 15 can reduce shaking and deformation when the culture dish is fixed.
[0031] The above description is only a preferred specific implementation manner of the present invention, but the protection scope of the present invention is not limited thereto. Any technician familiar with the technical field can make equivalent replacements or changes within the technical scope disclosed by the present invention according to the technical scheme and the utility model concept of the present invention, which should be covered by the protection scope of the present invention.
Claims
1. A human stem cell culture instrument, characterized in that: The invention comprises a culture instrument body (1), wherein a placement component for placing a culture dish is installed inside the body (1), wherein the placement component comprises a plurality of fixing frames (2) arranged in parallel, wherein the fixing frames (2) are connected to the inner wall of the body (1) via a pull-out component, and a plurality of fixing components for preventing the culture dish from shaking are installed on the top of the fixing frames (2); The fixing assembly comprises a plurality of sliding plates (3) mounted on a fixing frame (2), a plurality of notches (4) are respectively arranged on both sides of the sliding plates (3), the notches (4) on adjacent sliding plates (3) are arranged opposite to each other, the plurality of sliding plates (3) are connected by two guide rods (5), and a placement groove for placing a culture dish is formed between the notches (4) between two sliding plates (3).
2. A human stem cell culture apparatus according to claim 1, characterized in that: A plurality of partitions are provided on the guide rod (5) and between two adjacent sliding plates (3).
3. A human stem cell culture apparatus according to claim 2, characterized in that: The partition comprises a spring (7) mounted on two sliding plates (3).
4. A human stem cell culture apparatus according to claim 3, characterized in that: Limiting grooves (8) are respectively provided on both sides of the sliding plate (3), a sleeve (9) is connected between two opposite limiting grooves (8), and the sleeve (9) is located between two adjacent limiting grooves (8).
5. A human stem cell culture apparatus according to claim 4, characterized in that: A positioning plate (10) is provided at one end of the fixing frame (2), one of the sliding plates (3) located at the end is fixedly connected to the positioning plate (10), and a shifting plate (11) is provided on a sliding plate (3) opposite to the positioning plate (10).
6. A human stem cell culture apparatus according to claim 5, characterized in that: The fixing frame (2) is provided with a gusset plate (12), the gusset plate (12) is arranged opposite to the positioning plate (10), and the gusset plate (12) is clamped with the shifting plate (11).
7. A human stem cell culture apparatus according to claim 6, characterized in that: The drawer assembly comprises slide blocks (13) mounted on both sides of a fixing frame (2), and a slide groove (14) is provided on the inner wall of the body (1).