Gene diagnosis kit for high-throughput sequencing

Abstract

The utility model relates to the technical field of kits, and discloses a gene diagnosis kit for high-throughput sequencing, which comprises three stacked placing boxes and a counterweight bottom plate, the three placing boxes are respectively a lower box body, a middle box body and an upper box body, T-shaped slide rails are arranged on two sides of the top of the counterweight bottom plate, two sides of the top of the lower box body and two sides of the top of the middle box body, and the counterweight bottom plate is provided with a lower box body and a middle box body. T-shaped sliding grooves are formed in the two sides of the bottom of the lower box body, the two sides of the bottom of the middle box body and the two sides of the bottom of the upper box body correspondingly, baffles are fixedly connected to the tops of the two ends of the balance weight bottom plate correspondingly, positioning grooves are formed in the two sides of the three containing boxes correspondingly, and positioning assemblies are arranged on the sides, located on the containing boxes, of the baffles correspondingly. The positioning assembly comprises a supporting shaft, a connecting rod, a first spring, a positioning block, a pressing block and a locking assembly. Through the arrangement of the baffle and the positioning assembly, when a certain containing box is taken, the containing box can be taken out in a sliding mode only by pressing the pressing blocks on the two corresponding sides, and operation is more convenient.

Description

Technical Field

[0001] The utility model relates to the technical field of kits, in particular to a gene diagnosis kit for high-throughput sequencing. Background Art

[0002] High-throughput sequencing is also called next-generation sequencing. Compared with the first-generation Sanger sequencing, it is also called second-generation sequencing. As the name suggests, it can sequence hundreds of thousands to millions of DNA molecules in parallel at a time. It has the advantages of being more, faster, better, and more economical. Its disadvantage is that the read length is limited, but it is still the mainstream of commercial sequencing.

[0003] Existing high-throughput sequencing gene diagnosis requires a large amount of reagents, and the reagents need to be stored in a kit. The existing Chinese patent with announcement number CN216187323U discloses a high-throughput sequencing gene diagnosis kit, including a top plate, an intermediate plate, a bottom plate and a box cover, wherein the intermediate plate and the top plate are sequentially arranged above the bottom plate, the box cover is rotatably connected to the top of the box cover, and a reinforcement strap is arranged on one side of the intermediate plate, and the reinforcement strap is arranged in two, and the two The reinforcing straps are symmetrically distributed in the middle position of the box cover, L-shaped limit blocks and positioning protrusions are melted on the front and rear side walls of the top plate, the middle plate and the bottom plate near the positions of the reinforcing straps, the front and rear sides of the bottom of the bottom plate are provided with grooves, a weighting plate is arranged under the bottom plate, rubber blocks are fixed at the four corners of the surface of the weighting plate, suction cup bodies are connected to the corners of the lower surface of the weighting plate, and a connecting plate is arranged between the two suction cup bodies distributed laterally.

[0004] With respect to the above-mentioned related technology, the inventors found that there are at least the following problems in the technology: during the actual use of the above-mentioned test kit, since the layers are connected by connecting belts, it is troublesome to take out a certain layer separately.

[0005] Therefore, how to design a high-throughput sequencing genetic diagnostic kit has become a problem that we currently need to solve. Utility Model Content

[0006] 1. Technical issues to be resolved

[0007] In view of the deficiencies in the prior art, the utility model provides a high-throughput sequencing gene diagnosis kit to solve the problems mentioned in the above background technology.

[0008] (II) Technical solution

[0009] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a gene diagnosis kit for high-throughput sequencing, comprising three stacked placement boxes and a counterweight base plate, the three placement boxes are respectively a lower box body, a middle box body and an upper box body, both sides of the top of the counterweight base plate, the lower box body and the middle box body are provided with T-shaped slide rails, both sides of the bottom of the lower box body, the middle box body and the upper box body are provided with T-shaped slide grooves, the tops of both ends of the counterweight base plate are fixedly connected with baffles, both sides of the three placement boxes are provided with positioning grooves, and the baffle is located on one side of each placement box and is provided with a positioning component;

[0010] The positioning assembly includes a support shaft, a connecting rod, a first spring, a positioning block, a pressing block and a locking assembly, the support shaft is fixedly connected in the baffle, the connecting rod is hinged on the support shaft, there are two first springs, and the two first springs are respectively abutted against one end of the positioning block and the pressing block, the positioning block slides through the inner side of the baffle, the pressing block slides through the outer side of the baffle, one side of the positioning block and the pressing block are fixedly connected with a slider, both ends of the connecting rod are provided with sliding holes, the slider slides in the sliding holes, and the locking assembly is arranged on one side of the pressing block.

[0011] Preferably, two grooves are formed on the tops of the three placement boxes, sponge blocks are embedded in the grooves, and a plurality of evenly distributed placement grooves are formed on the tops of the sponge blocks.

[0012] Preferably, a label is provided on the top surface of the sponge block on one side of each placement slot.

[0013] Preferably, a retractable handle is fixedly connected to the middle portion of the sponge block.

[0014] Preferably, a box cover is hinged on the top of the upper box body, and sponge pads are embedded in the bottom surfaces of the box cover, the upper box body and the middle box body.

[0015] Preferably, the locking assembly includes a second spring and a locking rod, the second spring is embedded in the baffle, the locking rod abuts against the end of the second spring, a shift block is provided on one side of the locking rod, and a locking groove is provided on one side of the pressing block.

[0016] (III) Beneficial effects

[0017] The utility model provides a high-throughput sequencing gene diagnosis kit, which has the following beneficial effects:

[0018] First, by setting the baffle and the positioning assembly, when taking a placement box, you only need to press the pressing blocks on the corresponding two sides to retract the pressing blocks into the baffle. Under the sliding cooperation of the slider and the sliding hole, the pressing blocks will drive the connecting rod to rotate around the supporting shaft, and the other end of the connecting rod will drive the positioning block to retract into the baffle under the sliding cooperation of the slider and the sliding hole, so that the placement box can be slid out, which is more convenient to operate.

[0019] Secondly, by setting a locking assembly, when the pressing block is pressed back into the baffle, the locking groove is aligned with the locking rod. At this time, the locking rod will be inserted into the locking groove under the elastic force of the second spring, locking the pressing block, and indirectly locking the positioning block at the same time, so that the positioning block remains in the baffle. There is no need to continue pressing the pressing block. After the placement box is put back, it is only necessary to move the dial block to move the locking rod out of the locking groove, so that the positioning block can be quickly inserted into the positioning groove to fix the placement box, further facilitating the operation. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1 It is a schematic diagram of the overall structure of the utility model;

[0021] Figure 2 It is a structural schematic diagram of the upper box body of the utility model;

[0022] Figure 3 It is a schematic diagram of the cross-sectional structure of the baffle of the utility model in a top view;

[0023] Figure 4 For this utility model Figure 3 Enlarged view of the structure at the middle locking component.

[0024] In the figure: 1. placement box; 11. lower box body; 12. middle box body; 13. upper box body; 14. T-shaped slide rail; 15. T-shaped slide groove; 16. positioning groove; 17. groove; 18. sponge block; 19. placement groove; 110. label; 111. retractable handle; 112. box cover; 113. sponge pad; 2. counterweight base plate; 21. baffle; 22. positioning assembly; 221. support shaft; 222. connecting rod; 223. first spring; 224. positioning block; 225. pressing block; 226. locking assembly; 2261. second spring; 2262. locking rod; 2263. dial block; 2264. locking groove; 227. slider; 228. sliding hole. DETAILED DESCRIPTION

[0025] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0026] In the description of the present invention, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise" and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the referred device or element must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation on the present invention.

[0027] In addition, the terms "first" and "second" are used for descriptive purposes only and cannot be understood as indicating or suggesting relative importance or implicitly indicating the number of technical features indicated. Therefore, the features defined as "first" and "second" may explicitly or implicitly include one or more of such features. In the description of the present utility model, "multiple" means two or more, unless otherwise clearly and specifically defined.

[0028] like Figure 1-4 As shown, the utility model provides a technical solution: a gene diagnosis kit for high-throughput sequencing, comprising three stacked placement boxes 1 and a counterweight bottom plate 2, the three placement boxes 1 respectively comprising a lower box body 11, a middle box body 12 and an upper box body 13, two grooves 17 are provided on the top of the three placement boxes 1, a sponge block 18 is embedded in the groove 17, a plurality of evenly distributed placement grooves 19 are provided on the top of the sponge block 18, a label 110 is provided on one side of each placement groove 19 on the top surface of the sponge block 18, the label 110 is used to facilitate classification and labeling of reagents in each placement groove 19, and to facilitate searching and taking, a retractable handle 111 is fixedly connected to the middle of the sponge block 18, the sponge block 18 can be taken out of the groove 17 individually by the retractable handle 111, and it is convenient to take and put the reagents placed in a single sponge block 18.

[0029] Furthermore, a box cover 112 is hinged on the top of the upper box body 13, and sponge pads 113 are embedded in the bottom surfaces of the box cover 112, the upper box body 13 and the middle box body 12. By providing the sponge pads 113, a buffering and protective effect can be provided for the tops of the reagents placed in the three placement boxes 1, thereby preventing the reagents from being subjected to severe impact during carrying.

[0030] Reference Figure 1-3 T-shaped slide rails 14 are provided on both sides of the top of the counterweight base plate 2, the lower box body 11 and the middle box body 12, and T-shaped slide grooves 15 are provided on both sides of the bottom of the lower box body 11, the middle box body 12 and the upper box body 13. Through the cooperation of the T-shaped slide rails 14 and the T-shaped slide grooves 15, the three placement boxes 1 can be individually pulled out and placed. The tops of both ends of the counterweight base plate 2 are fixedly connected with baffles 21, and positioning grooves 16 are provided on both sides of the three placement boxes 1. The baffle 21 is located on one side of each placement box 1 and a positioning component 22 is provided. By setting the baffle 21 and the positioning component 22, the baffle 21 can shield the two sides of the placement box 1, and the positioning component 22 can connect and fix the placement box 1 to the baffle 21.

[0031] Specifically, the positioning assembly 22 includes a support shaft 221, a connecting rod 222, a first spring 223, a positioning block 224, a pressing block 225 and a locking assembly 226. The support shaft 221 is fixedly connected in the baffle 21, the connecting rod 222 is hinged on the support shaft 221, there are two first springs 223, and the two first springs 223 are respectively abutted against one end of the positioning block 224 and the pressing block 225, the positioning block 224 slides through the inner side of the baffle 21, and the pressing block 225 slides through the outer side of the baffle 21, and one side of the positioning block 224 and the pressing block 225 is fixedly connected with a slider 227, and the connecting Both ends of the rod 222 are provided with sliding holes 228, and the slider 227 slides in the sliding hole 228. By setting the positioning component 22, when taking a certain placement box 1, it is only necessary to press the pressing blocks 225 on the corresponding sides to retract the pressing blocks 225 into the baffle 21. Under the sliding cooperation of the slider 227 and the sliding hole 228, the pressing block 225 will drive the connecting rod 222 to rotate around the supporting shaft 221, and the other end of the connecting rod 222 will drive the positioning block 224 to retract into the baffle 21 under the sliding cooperation of the slider 227 and the sliding hole 228, so that the placement box 1 can be slid out, and the operation is more convenient.

[0032] Specifically, the locking assembly 226 is arranged on one side of the pressing block 225, and the locking assembly 226 includes a second spring 2261 and a locking rod 2262. The second spring 2261 is embedded and installed in the baffle 21, and the locking rod 2262 abuts against the end of the second spring 2261. A shift block 2263 is provided on one side of the locking rod 2262, and a locking groove 2264 is provided on one side of the pressing block 225. By setting the locking assembly 226, when the pressing block 225 is pressed back into the baffle 21, the locking groove 2264 is aligned with the locking rod 2262. When the locking rod 2262 is in the locking groove 2264, the locking rod 2262 can be inserted into the locking groove 2264 under the elastic force of the second spring 2261, thereby locking the pressing block 225 and indirectly locking the positioning block 224, so that the positioning block 224 is kept in the baffle 21. There is no need to continuously press the pressing block 225. After the placement box 1 is put back, it is only necessary to move the shift block 2263 to move the locking rod 2262 out of the locking groove 2264, so that the positioning block 224 can be quickly inserted into the positioning groove 16 to fix the placement box 1, thereby further facilitating the operation.

[0033] The working process of the utility model is as follows: by setting the baffle plate 21 and the positioning assembly 22, when taking a certain placement box 1, it is only necessary to press the pressing blocks 225 on the corresponding two sides to retract the pressing blocks 225 into the baffle plate 21, and under the sliding cooperation of the slider 227 and the sliding hole 228, the pressing block 225 will drive the connecting rod 222 to rotate around the support shaft 221, and the other end of the connecting rod 222 will drive the positioning block 224 to retract into the baffle plate 21 under the sliding cooperation of the slider 227 and the sliding hole 228. When the pressing block 225 is pressed and compressed, the baffle plate 2 1, the locking groove 2264 is just aligned with the locking rod 2262. At this time, the locking rod 2262 will be inserted into the locking groove 2264 under the elastic force of the second spring 2261, and the pressing block 225 will be locked. At the same time, the positioning block 224 will be indirectly locked. At this time, the placement box 1 can be slid out. After the placement box 1 is put back, it is only necessary to toggle the toggle block 2263 to move the locking rod 2262 out of the locking groove 2264, so that the positioning block 224 can be quickly inserted into the positioning groove 16, and the placement box 1 is fixed, which is convenient for operation.

[0034] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device.

[0035] Although the embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A high-throughput sequencing gene diagnosis kit, comprising three stacked placement boxes (1) and a weighted bottom plate (2), characterized in that: The three placement boxes (1) are respectively a lower box body (11), a middle box body (12) and an upper box body (13); both sides of the top of the counterweight base plate (2), the lower box body (11) and the middle box body (12) are provided with T-shaped slide rails (14); both sides of the bottom of the lower box body (11), the middle box body (12) and the upper box body (13) are provided with T-shaped slide grooves (15); the tops of both ends of the counterweight base plate (2) are fixedly connected with baffles (21); both sides of the three placement boxes (1) are provided with positioning grooves (16); and a positioning component (22) is provided on one side of each placement box (1); The positioning assembly (22) comprises a support shaft (221), a connecting rod (222), a first spring (223), a positioning block (224), a pressing block (225) and a locking assembly (226); the support shaft (221) is fixedly connected in the baffle (21); the connecting rod (222) is hinged on the support shaft (221); there are two first springs (223), and the two first springs (223) are respectively in contact with the positioning block (224) and the pressing block (225). The connecting rod (222) is provided with a sliding hole (228) at both ends thereof, the sliding block (227) slides in the sliding hole (228), and the locking assembly (226) is arranged on one side of the pressing block (225).

2. A high-throughput sequencing gene diagnosis kit according to claim 1, characterized in that: The tops of the three placement boxes (1) are each provided with two grooves (17), a sponge block (18) is embedded in the grooves (17), and the top of the sponge block (18) is provided with a plurality of evenly distributed placement grooves (19).

3. A high-throughput sequencing gene diagnosis kit according to claim 2, characterized in that: The top surface of the sponge block (18) is provided with a label (110) on one side of each placement groove (19).

4. A high-throughput sequencing gene diagnosis kit according to claim 2, characterized in that: A retractable handle (111) is fixedly connected to the middle of the sponge block (18).

5. The high-throughput sequencing gene diagnosis kit according to claim 1, characterized in that: The top of the upper box body (13) is hinged with a box cover (112), and the bottom surfaces of the box cover (112), the upper box body (13) and the middle box body (12) are all embedded with sponge pads (113).

6. A high-throughput sequencing gene diagnosis kit according to claim 5, characterized in that: The locking assembly (226) includes a second spring (2261) and a locking rod (2262), wherein the second spring (2261) is embedded in the baffle (21), the locking rod (2262) abuts against the end of the second spring (2261), a shift block (2263) is provided on one side of the locking rod (2262), and a locking groove (2264) is provided on one side of the pressing block (225).

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