Multi-stage ultrasonic crushing device for continuous sample injection
By designing a continuous ultrasonic crushing device with buffer ears and multi-stage crushing tanks, the problems of low ultrasonic crushing efficiency and unreplicable environment when the output is expanded are solved, and experimental results of efficient and uniform crushing and replicable are achieved.
Patent Information
- Application Number
- CN202420606495.1
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-03-26
- Publication Date
- 2025-01-14
- Estimated Expiration
- 2034-03-26
AI Technical Summary
The existing ultrasonic crushing devices are inefficient during operation, difficult to process continuous flowing solutions, and difficult to buffer the impact force, resulting in uneven crushing, and the experimental environment is not replicable when expanding the output, affecting the experimental results.
A continuous injection multi-stage ultrasonic crushing device is designed, including buffer ears and multi-stage crushing tanks. The impact force is dispersed through buffer ears to ensure continuous work, and replicable efficient crushing is achieved through multi-stage crushing tanks, using low The connection method of high inlet and outflow prevents the sample from being extruded by impact force and enhances crushing uniformity.
It achieves efficient and uniform sample crushing, ensures the replicability of experimental results and the scalability of yield, and solves the problems of ultrasonic impact force dispersion and yield expansion.
Smart Images
Figure CN222343062U_ABST
Abstract
Description
Technical Field
[0001] The utility model belongs to the technical field of ultrasonic crushing, and in particular relates to a multi-stage ultrasonic crushing device with continuous sampling. Background Art
[0002] Ultrasonic fragmentation technology utilizes the dispersion effect of ultrasound in liquid to produce cavitation effect in liquid, thereby breaking up solid particles or cell tissues in the liquid. Its main function is to quickly and effectively break up biological samples. It breaks up samples through high-frequency oscillating ultrasound, and has the advantages of simple operation, high fragmentation efficiency, and little damage to samples.
[0003] Ultrasonic disruption technology can be used to disrupt animal and plant tissues, cells, bacteria, and spore-forming bacteria, to prepare liposomes or nanoparticles, etc. It can also be used for emulsification, separation, dispersion, homogenization, extraction, degassing, cleaning, and acceleration of chemical reactions. It is widely used in biochemistry, microbiology, medicinal chemistry, surface chemistry, organic chemistry, inorganic chemistry, physics, zoology, agronomy, medicine, pharmaceuticals, and other fields, laboratory research, and corporate production.
[0004] However, the existing ultrasonic crushing device has the following defects when working:
[0005] 1. Generally, the horn is directly placed inside the reaction vessel for use, and ultrasound is directly performed using the horn, which makes the ultrasound efficiency low, and it is difficult to achieve the crushing effect for the continuously flowing solution (sample), affecting the normal working efficiency;
[0006] 2. Ultrasonic waves will produce cavitation effect when working, and will have a certain impact force. If the impact force cannot be released and buffered, it will be difficult to pump the solution (sample) into the reaction vessel, resulting in the inability to form continuous crushing work;
[0007] 3. When it is necessary to expand the production, only higher-power ultrasound can be used for ultrasonic treatment, which results in the experimental solution (sample) treatment environment and ultrasonic conditions not being reproducible. Individual solutions (samples) may present different experimental results under different powers of ultrasound, and cannot be reproduced for production;
[0008] 4. After the ultrasonic wave passes through the reaction container containing the solution (sample), the energy decreases step by step, which makes the cells in the reaction container unevenly broken and affects the cell breaking effect. Utility Model Content
[0009] The utility model aims to provide a multi-stage ultrasonic crushing device for continuous sample feeding to solve the problems raised in the above background technology.
[0010] To achieve the above-mentioned purpose, the utility model provides the following technical solution: a multi-stage ultrasonic crushing device for continuous sampling, comprising a box, wherein:
[0011] The box body is provided with a storage space for accommodating the installation of a storage container, and the box body is provided with a crushing space for accommodating the installation of a crushing tank;
[0012] A crushing chamber is provided in the crushing tank, and an ultrasonic horn is inserted into the crushing chamber;
[0013] The crushing tank is provided with a buffer ear outside, the buffer ear is connected with the upper and lower ends of the crushing tank, and the buffer ear disperses the impact force of the lower end of the crushing chamber to the upper end of the crushing chamber;
[0014] The storage container is connected to the inlet arranged at the bottom of the crushing tank through a connecting hose, and the medium in the connecting hose flows unidirectionally from the storage container to the crushing tank;
[0015] The outlet arranged at the bottom of the crushing tank is connected to the collecting container through a connecting hose, and the medium in the crushing tank flows unidirectionally from the crushing tank to the collecting container.
[0016] Preferably, a buffer cavity is provided in the buffer ear, the buffer cavity is connected with the crushing cavity, and the buffer cavity connects the lower end of the crushing cavity with the upper end of the crushing cavity to form a buffer channel.
[0017] Preferably, the buffer ears are arranged in a U-shaped structure, and a plurality of the buffer ears are arranged in an array along the axis of the crushing tank.
[0018] Preferably, the inlet of the adjacent crushing tank is connected to the outlet of the adjacent crushing tank through a connecting hose, and the medium in the adjacent crushing tank flows unidirectionally from the direction of the storage container to the direction of the collection container.
[0019] Preferably, the crushing tank is a sealed container, and the ultrasonic horn is fixedly connected to the upper cover of the crushing tank via a flange.
[0020] Preferably, a mounting frame is provided in the box body, and the mounting frame is detachably connected to a support ring on the ultrasonic horn.
[0021] Preferably, a plurality of ultrasonic welding heads are arrayed on the ultrasonic horn.
[0022] Preferably, a control cabinet for accommodating and storing the ultrasonic generator is provided in the box body, a touch control screen is provided outside the control cabinet, and the ultrasonic generator is electrically connected to the ultrasonic transducer arranged on the top of the ultrasonic horn through a connecting line.
[0023] Preferably, the collecting container is connected to the storage container via a circulation hose, and the medium in the circulation hose flows unidirectionally from the collecting container to the storage container.
[0024] Preferably, a peristaltic pump is provided on the connecting hose, and a peristaltic pump is provided on the circulation hose.
[0025] The technical effects and advantages of the utility model are as follows:
[0026] 1. By inserting an ultrasonic horn in the crushing chamber and setting multiple ultrasonic welding heads on the same ultrasonic horn, the crushing area in the crushing tank can be enlarged, the crushing efficiency can be guaranteed, and the sample in the crushing tank can be evenly crushed;
[0027] 2. By connecting the buffer ear with the upper and lower ends of the crushing tank, the impact force at the lower end of the crushing chamber can be dispersed to the upper end of the crushing chamber. In this way, when the ultrasonic wave is working, the impact force can be dispersed upward through the buffer ear, which can offset the impact force generated by the ultrasonic wave, reduce the impact on the peristaltic pump, and can continuously perform cyclic crushing work;
[0028] 3. The crushing tank can be used as a single group, or multiple crushing tanks of the same specifications can be connected through a connecting hose, and multiple groups can be copied for multi-level use in the same environment at the same time. This solves the problem that when a small amount of samples needs to be expanded after ultrasonic experiments, the sample processing environment during the experiment can be expanded without changing the sample processing environment during the experiment. It is repeatable and can expand the output infinitely according to demand, solving the problem that the experimental product cannot be replicated for production;
[0029] 4. The crushing tank adopts a low-in and high-out connection method, which can prevent the sample from being squeezed out of the crushing tank by the impact force of the ultrasound before it is crushed by the ultrasound. It can make the sample in the crushing tank crushed evenly and increase the sample crushing effect. BRIEF DESCRIPTION OF THE DRAWINGS
[0030] Figure 1 It is a schematic diagram of the structure of the utility model;
[0031] Figure 2 It is a schematic diagram of the specific structure of the utility model;
[0032] Figure 3 It is a schematic diagram of the internal structure of the utility model;
[0033] Figure 4 This is a schematic diagram of the structure of the utility model wherein the crushing tank is used in multiple stages;
[0034] Figure 5 This is a schematic diagram of the structure of the crushing tank of the utility model;
[0035] Figure 6It is a cross-sectional view of the crushing tank of the utility model;
[0036] Figure 7 It is a schematic diagram of the buffer channel of the utility model.
[0037] In the figure:
[0038] 1. Box; 2. Storage container; 3. Crushing tank; 4. Ultrasonic horn; 5. Buffer ear; 6. Connecting hose; 7. Collection container; 8. Buffer channel; 9. Circulation hose; 10. Peristaltic pump;
[0039] 11. Storage space; 12. Crushing space; 13. Flange; 14. Mounting frame; 15. Control chassis; 16. Touch control screen; 17. Connecting wire;
[0040] 31. Crushing chamber; 32. Inlet; 33. Outlet;
[0041] 41. bracket ring; 42. ultrasonic welding head; 43. ultrasonic transducer;
[0042] 51. Buffer chamber. DETAILED DESCRIPTION
[0043] The following will be combined with the attached embodiment of the utility model Figure 1-7 , clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of them. Based on the embodiments of the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.
[0044] The utility model provides Figure 1-Figure 7 A multi-stage ultrasonic crushing device with continuous sampling as shown in the figure comprises a housing 1, wherein:
[0045] The box body 1 is provided with a storage space 11 for accommodating the storage container 2 , and the box body 1 is provided with a crushing space 12 for accommodating the crushing tank 3 .
[0046] A crushing chamber 31 is provided in the crushing tank 3, and an ultrasonic horn 4 is inserted into the crushing chamber 31. By inserting the ultrasonic horn 4 into the crushing tank 3, the crushing area in the crushing tank 3 can be increased, the crushing efficiency can be guaranteed, and it can be ensured that the sample in the crushing tank 3 can be evenly crushed.
[0047] Moreover, in the present invention, the ultrasonic horn 4 is inserted in the center of the crushing chamber 31, so that the bottom end of the ultrasonic horn 4 is suspended and extends into the crushing tank 3. Due to the cavitation effect generated by the ultrasonic wave in the liquid, the ultrasonic horn 4 can vibrate and crush the sample in the crushing chamber 31, and the sample is crushed by utilizing the high-frequency oscillation force of the ultrasonic wave.
[0048] The crushing tank 3 is provided with a buffer ear 5 outside, and the buffer ear 5 is connected with the upper and lower ends of the crushing tank 3, and the buffer ear 5 disperses the impact force of the lower end of the crushing chamber 31 to the upper end of the crushing chamber 31. In this way, when the ultrasonic wave is working, the impact force can be dispersed upward through the buffer ear 5, which can offset the impact force generated by the ultrasonic wave work, reduce the impact force on the peristaltic pump 10, and reduce the impact on the peristaltic pump 10, ensuring that the peristaltic pump 10 can pump the sample solution into the crushing tank 3, and can continuously perform the cyclic crushing work.
[0049] The storage container 2 is connected to the inlet 32 arranged at the bottom of the crushing tank 3 through the connecting hose 6, and the medium in the connecting hose 6 flows unidirectionally from the storage container 2 to the crushing tank 3; the outlet 33 arranged at the bottom of the crushing tank 3 is connected to the collecting container 7 through the connecting hose 6, and the medium in the crushing tank 3 flows unidirectionally from the crushing tank 3 to the collecting container 7.
[0050] Since ultrasound has impact force, if the crushing tank 3 adopts a high-input and low-output connection, the sample solution at the bottom of the crushing tank 3 may not have time to be crushed by the ultrasound and may be squeezed out of the crushing tank 3 by the impact force of the ultrasound. Therefore, in the utility model, the crushing tank 3 adopts a low-input and high-output connection method, which can prevent the sample from being squeezed out of the crushing tank 3 by the impact force of the ultrasound before being crushed by the ultrasound, so that the sample in the crushing tank 3 can be crushed evenly, thereby increasing the sample crushing effect.
[0051] Specifically, a buffer chamber 51 is provided in the buffer ear 5, and the buffer chamber 51 is connected with the crushing chamber 31, and the buffer chamber 51 connects the lower end of the crushing chamber 31 with the upper end of the crushing chamber 31 to form a buffer channel 8. Since the crushing tank 3 adopts a low-input and high-output connection method, the buffer chamber 51 in the buffer ear 5 is connected with the crushing chamber 31. In this way, the impact force generated during the operation of the ultrasonic wave can be dispersed upward through the buffer channel 8, thereby reducing the impact on the peristaltic pump 10.
[0052] Specifically, the buffer ears 5 are arranged in a U-shaped structure, and a plurality of the buffer ears 5 are arranged in an array along the axis of the crushing tank 3, wherein the number of the buffer ears 5 is set to be at least 1, but in order to evenly disperse the impact force on both sides of the crushing tank 3, it is best to set the number of the buffer ears 5 to an even number.
[0053] In the present invention, the number of the buffer ears 5 is two, and the two buffer ears 5 are arranged corresponding to each other.
[0054] Specifically, the inlet 32 of the adjacent crushing tank 3 is connected to the outlet 33 of the adjacent crushing tank 3 through the connecting hose 6, and the medium in the adjacent crushing tank 3 flows unidirectionally from the storage container 2 to the collecting container 7. In this way, the crushing tank 3 can be used as a single group, or multiple crushing tanks 3 of the same specification can be connected through the connecting hose 6, and multiple groups can be replicated for multi-stage use in the same environment at the same time, which solves the problem that when a small amount of samples needs to be expanded after ultrasonic experiments, the sample processing environment during the experiment needs to be expanded without changing the sample processing environment. It has repeatability and can expand the output infinitely according to demand, which solves the problem that the experimental products cannot be replicated for production.
[0055] Specifically, the crushing tank 3 is a sealed container, and the ultrasonic horn 4 is fixedly connected to the upper cover of the crushing tank 3 via a flange 13. The ultrasonic horn 4 is fixedly connected to the upper cover of the crushing tank 3 via the flange 13, which can ensure the sealing of the crushing tank 3.
[0056] Furthermore, in the present invention, the ultrasonic horn 4 is fixedly connected to the upper cover of the crushing tank 3 by the flange 13, which can ensure that the ultrasonic horn 4 is always located at the center of the crushing tank 3, and ensure that the position of the crushing tank 3 is not affected by ultrasonic vibration, thereby preventing the crushing tank 3 from moving.
[0057] Specifically, a mounting frame 14 is provided in the box body 1, and a plurality of mounting holes are arranged in an array on the mounting frame 14, and the mounting frame 14 is detachably connected to the bracket ring 41 on the ultrasonic horn 4. By inserting the ultrasonic horn 4 into the mounting hole, and then connecting the bracket ring 41 on the ultrasonic horn 4 to the mounting frame 14 in a detachable manner through bolts, installation expansion is facilitated, and a corresponding number of ultrasonic horn 4 can be selected as needed.
[0058] Specifically, a plurality of ultrasonic horns 42 are arrayed on the ultrasonic horn 4. By arranging a plurality of ultrasonic horns 42 on the same ultrasonic horn 4, the crushing area in the crushing tank 3 can be increased, the crushing efficiency can be guaranteed, and it can be ensured that the sample in the crushing tank 3 can be crushed evenly.
[0059] Specifically, a control box 15 for accommodating and storing an ultrasonic generator is disposed inside the box body 1 , a touch control screen 16 is disposed outside the control box 15 , and the ultrasonic generator is electrically connected to an ultrasonic transducer 43 disposed on the top of the ultrasonic horn 4 via a connecting line 17 .
[0060] In the utility model, the ultrasonic generator is connected to the ultrasonic transducer 43 through a connecting line 17, and an ultrasonic horn 4 is installed at the bottom of the ultrasonic transducer 43, wherein the ultrasonic generator is responsible for converting alternating current into high-frequency electrical energy for use by the ultrasonic transducer 43; the ultrasonic transducer 43 is responsible for converting electrical energy into ultrasonic vibration; the ultrasonic horn 4 cooperates with the ultrasonic transducer 43 to increase the amplitude of ultrasonic vibration, and then transmits the vibration to the sample through the ultrasonic welding head 42. Since the vibration speed is extremely fast, which can reach tens of thousands of times per second or even higher, tiny cavitation bubbles can be generated in the sample. Under a certain pressure difference, these cavitation bubbles will collapse rapidly, thereby generating powerful microjets, causing the film on the surface of the sample to be destroyed, thereby realizing the crushing of the sample in the crushing tank 3 by the high-frequency oscillation force of the ultrasonic wave.
[0061] In the utility model, the power of the ultrasonic generator is adjustable, and the power can be adjusted according to the processing amount.
[0062] Specifically, the collection container 7 is connected to the storage container 2 through the circulation hose 9, and the medium in the circulation hose 9 flows unidirectionally from the collection container 7 to the storage container 2. In this way, the sample can be extracted from the collection container 7 and then sent back to the storage container 2, forming a cycle, which can promote the flow of the sample and perform repeated crushing work.
[0063] Specifically, a peristaltic pump 10 is provided on the connecting hose 6, and the sample can be pumped from the storage container 2 to the crushing tank 3 through the peristaltic pump 10 on the connecting hose 6; a peristaltic pump 10 is provided on the circulation hose 9, and the crushed sample can be pumped from the collection container 7 to the storage container 2 through the peristaltic pump 10 on the circulation hose 9.
[0064] In the present invention, the peristaltic pump 10 can be used to prevent the volatile gas in the sample solution from entering the pump, thereby preventing the volatile gas from affecting the performance and life of the pump.
[0065] Working principle:
[0066] Before using the multi-stage ultrasonic crushing device with continuous sampling, first add the sample to be crushed into the storage container 2 through the injection device, then select the corresponding number of ultrasonic horn rods 4 according to the sample to be crushed, and combine the determined number of ultrasonic horn rods 4 with the corresponding crushing tanks 3 and fix them on the mounting frame 14.
[0067] Then, a low-in and high-out connection method is adopted. The crushing tank 3 is first connected through the connecting hose 6, the storage container 2 is connected to the inlet 32 set at the bottom of the first crushing tank 3 through the connecting hose 6, and the outlet 33 set at the bottom of the last crushing tank 3 is connected to the collecting container 7 through the connecting hose 6.
[0068] When the multi-stage ultrasonic crushing device with continuous sampling is in use, the sample solution in the storage container 2 is pumped into the crushing tank 3 through the peristaltic pump 10 on the connecting hose 6, and is continuously crushed by the multi-stage ultrasonic horn 4. After multiple groups of ultrasonic crushing, the crushed sample solution is collected in the collection container 7.
[0069] After the crushing treatment, the crushing effect of the sample solution can be checked. If the collected processed sample solution does not meet expectations, the processed sample solution in the collection container 7 is pumped into the storage container 2 through the peristaltic pump 10 on the circulation hose 9 for repeated crushing. After all the processed sample solution in the collection container 7 is transferred to the storage container 2, the ultrasonic horn 4 is started again to perform repeated crushing.
[0070] Finally, it should be noted that the above is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Although the present utility model has been described in detail with reference to the aforementioned embodiments, it is still possible for those skilled in the art to modify the technical solutions described in the aforementioned embodiments, or to make equivalent substitutions for some of the technical features therein. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present utility model shall be included in the protection scope of the present utility model.
Claims
1. A multi-stage ultrasonic crushing device for continuous sample introduction, comprising a housing (1), characterized in that: The box body (1) is provided with a storage space (11) for accommodating the installation of the storage container (2), and the box body (1) is provided with a crushing space (12) for accommodating the installation of the crushing tank (3); The crushing tank (3) is provided with a crushing chamber (31), and an ultrasonic horn (4) is inserted into the crushing chamber (31); The crushing tank (3) is provided with a buffer ear (5) outside, the buffer ear (5) is connected to the upper and lower ends of the crushing tank (3), and the buffer ear (5) disperses the impact force at the lower end of the crushing chamber (31) to the upper end of the crushing chamber (31); The storage container (2) is connected to an inlet (32) arranged at the bottom of the crushing tank (3) through a connecting hose (6), and the medium in the connecting hose (6) flows unidirectionally from the storage container (2) to the crushing tank (3); An outlet (33) arranged at the bottom of the crushing tank (3) is connected to a collecting container (7) via a connecting hose (6), and the medium in the crushing tank (3) flows unidirectionally from the crushing tank (3) to the collecting container (7).
2. A multi-stage ultrasonic crushing device for continuous sampling according to claim 1, characterized in that: A buffer chamber (51) is provided in the buffer ear (5), the buffer chamber (51) is connected to the crushing chamber (31), and the buffer chamber (51) connects the lower end of the crushing chamber (31) with the upper end of the crushing chamber (31) to form a buffer channel (8).
3. A multi-stage ultrasonic crushing device for continuous sampling according to claim 1, characterized in that: The buffer ears (5) are arranged in a U-shaped structure, and a plurality of the buffer ears (5) are arranged in an array along the axis of the crushing tank (3).
4. A multi-stage ultrasonic crushing device for continuous sampling according to claim 1, characterized in that: The inlet (32) of the adjacent crushing tank (3) is connected to the outlet (33) of the adjacent crushing tank (3) through a connecting hose (6), and the medium in the adjacent crushing tank (3) flows unidirectionally from the storage container (2) to the collection container (7).
5. A multi-stage ultrasonic crushing device for continuous sampling according to claim 1, characterized in that: The crushing tank (3) is a sealed container, and the ultrasonic horn (4) is fixedly connected to the upper cover of the crushing tank (3) via a flange (13).
6. A multi-stage ultrasonic crushing device for continuous sampling according to claim 1, characterized in that: A mounting frame (14) is provided in the box body (1), and the mounting frame (14) is detachably connected to a support ring (41) on the ultrasonic horn (4).
7. A multi-stage ultrasonic crushing device for continuous sampling according to claim 1, characterized in that: A plurality of ultrasonic welding heads (42) are arranged in an array on the ultrasonic horn (4).
8. A multi-stage ultrasonic crushing device for continuous sampling according to claim 1, characterized in that: The box body (1) is provided with a control box (15) for accommodating and installing an ultrasonic generator, and the control box (15) is provided with a touch control screen (16) outside. The ultrasonic generator is electrically connected to an ultrasonic transducer (43) arranged on the top of the ultrasonic horn (4) via a connecting line (17).
9. A multi-stage ultrasonic crushing device for continuous sampling according to claim 1, characterized in that: The collecting container (7) is connected to the storage container (2) via a circulation hose (9), and the medium in the circulation hose (9) flows in a unidirectional manner from the collecting container (7) to the storage container (2).
10. A multi-stage ultrasonic crushing device for continuous sampling according to claim 1 or 9, characterized in that: A peristaltic pump (10) is provided on the connecting hose (6), and a peristaltic pump (10) is provided on the circulation hose (9).