PCR (Polymerase Chain Reaction) tube gland device

By designing an automated PCR tube gland device, the mechanical structure of adjusting the telescopic rod and connecting block is used to achieve rapid sealing of PCR tubes, solving the problems of manual sealing time and hand fatigue, and improving sealing efficiency and safety.

CN222348651UActive Publication Date: 2025-01-14SUZHOU ACUMEN BIOMEDICAL TECH CO LTD
View PDF 0 Cites 0 Cited by

Patent Information

Application Number
CN202420991084.9
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-05-09
Publication Date
2025-01-14
Estimated Expiration
2034-05-09

AI Technical Summary

Technical Problem

Existing PCR tube sealing processes require manual pressing of the tube cover, which can cause time-consuming and can cause acidity and pain in the hands, especially when dealing with multiple PCR tubes.

Method used

A PCR tube gland device is designed, including a base plate, mounting groove, connecting block, adjusting telescopic rod and cap assembly. By adjusting the telescopic rod and pushing the connecting block, the placement frame and cap assembly are driven to contact the PCR tube. , realizes automated sealing, and improves rotational ease and friction through fixing bolts and rubber sleeves, allowing adjustment of seal depth.

Benefits of technology

The rapid and automated sealing of PCR tubes is achieved, reducing the time and labor intensity of manual operation, reducing the risk of hand fatigue and pain, and improving the flexibility of adjusting the seal depth.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN222348651U_ABST
    Figure CN222348651U_ABST
Patent Text Reader

Abstract

The utility model discloses a PCR (Polymerase Chain Reaction) tube capping device, which belongs to the technical field of PCR tube capping, and adopts the technical scheme that the PCR tube capping device comprises a bottom plate, the top of the bottom plate is provided with a mounting groove, the inner wall of the mounting groove is connected with a connecting block in a sliding manner, the top of the connecting block is fixedly connected with a placement frame, the left side of the bottom plate is fixedly connected with an adjusting telescopic rod, and the left side of the bottom plate is fixedly connected with an adjusting telescopic rod. The output end of the adjusting telescopic rod penetrates through the bottom plate and the mounting groove and is fixedly connected with the left side of the connecting block, and the rear side of the top of the bottom plate is fixedly connected with a gland assembly. The gland assembly comprises a square rod, the bottom of the square rod is fixedly connected with the rear side of the top of the bottom plate, and the problems that when existing PCR tubes are sealed, most of the PCR tubes are sealed by manually pressing tube covers by laboratory workers, and when the PCR tubes are many, the PCR tube sealing work is time-consuming, and continuous pressing work is poor are solved. And hands of workers are easy to feel sour and painful.
Need to check novelty before this filing date? Find Prior Art

Description

Technical Field

[0001] The utility model relates to the technical field of PCR tube capping, in particular to a PCR tube capping device. Background Art

[0002] PCR tube is a laboratory tool used for polymerase chain reaction. It is usually made of polypropylene and has the characteristics of high temperature resistance and chemical corrosion resistance. PCR tube is usually cylindrical, with a closed bottom and an open top, which can hold PCR reaction solution and reactants.

[0003] When conducting reaction experiments in the laboratory, a capping device is used to cap and seal the PCR tubes, and the PCR tube capping device is one of them. However, when sealing the existing PCR tubes, most of them are sealed by laboratory staff manually pressing the tube caps. When there are many PCR tubes, the sealing work of the PCR tubes is time-consuming, and the continuous pressing work is likely to cause soreness and pain in the hands of the staff. Therefore, a PCR tube capping device is proposed. Utility Model Content

[0004] The utility model provides a PCR tube capping device, which aims to solve the problem that, in the existing PCR tubes, most of the sealing is done by laboratory staff manually pressing the tube caps, and when there are many PCR tubes, the PCR tube sealing work is time-consuming, and the continuous pressing work is likely to cause soreness and pain in the hands of the staff.

[0005] The utility model is implemented as follows: a PCR tube capping device comprises a bottom plate, a mounting groove is provided on the top of the bottom plate, a connecting block is slidably connected to the inner wall of the mounting groove, a placing rack is fixedly connected to the top of the connecting block, an adjusting telescopic rod is fixedly connected to the left side of the bottom plate, an output end of the adjusting telescopic rod passes through the bottom plate and the mounting groove, and is fixedly connected to the left side of the connecting block, and a capping assembly is fixedly connected to the rear side of the top of the bottom plate;

[0006] The pressure cover assembly includes a square rod, the bottom of the square rod is fixedly connected to the rear side of the top of the base plate, the surface of the square rod is slidably connected to an adjustment block, the inner wall of the rear side of the adjustment block is rotatably connected to a fixing bolt, the fixing bolt passes through the adjustment block and the square rod, and extends to the inner wall of the front side of the adjustment block, the front side of the adjustment block is fixedly connected to a positioning column, and the surface of the positioning column is rotatably connected to a ring block.

[0007] In order to assist in guiding the telescopic position of the output end of the adjustable telescopic rod, a PCR tube capping device is preferably provided in the utility model, wherein a guide hole is provided on the left side of the bottom plate, the guide hole is circular, and the inner wall of the guide hole contacts the output end of the adjustable telescopic rod.

[0008] In order to assist in guiding the placement position of the PCR tube, as a preferred PCR tube capping device of the utility model, a plurality of placement holes are provided on the top of the placement rack, and a plurality of the placement holes are provided and are evenly distributed on the top of the placement rack.

[0009] In order to reinforce the placement rack, as a preferred PCR tube capping device of the utility model, the inner wall of the placement rack is fixedly connected with reinforcement rods, and there are four reinforcement rods in total, and the reinforcement rods are inclined.

[0010] In order to fix the adjustment block, as a preferred PCR tube capping device of the utility model, a threaded hole is opened on the front side of the square rod, and there are a total of several threaded holes, and the threaded patterns on the inner walls of the threaded holes are meshed with the threaded patterns on the surface of the fixing bolts.

[0011] In order to limit the position of the adjustment block during movement, as a preferred PCR tube capping device of the utility model, a through hole is opened on the top of the adjustment block, the inner wall of the through hole is slidably connected to a limiting rod, and the bottom of the limiting rod is fixedly connected to the rear side of the top of the base plate.

[0012] In order to limit the annular block, as a preferred PCR tube capping device of the utility model, the other end of the positioning column is fixedly connected to a positioning block used in conjunction with it, and the rear side of the positioning block contacts the front side of the annular block.

[0013] In order to improve the rotation convenience of the fixing bolt and increase the friction when rotating the rotary cover, as a preferred PCR tube capping device of the utility model, the surface of the fixing bolt is fixedly connected to the rotary cover used therewith, and the surface of the rotary cover is fixedly connected to a rubber sleeve.

[0014] Compared with the prior art, the beneficial effects of the utility model are:

[0015] The PCR tube capping device is provided with a bottom plate, a mounting groove, a connecting block, a placing rack, an adjusting telescopic rod and a capping assembly. The PCR tube can be placed in the placing rack, and then the tube cap is placed at the PCR tube connecting port. Then the adjusting telescopic rod is started, so that the adjusting telescopic rod can push the connecting block under the fixation of the bottom plate, and the placing rack and the placed PCR tube can be driven by the connecting block to contact the bottom of the capping assembly, and under the limit of the mounting groove, the moving position of the connecting block can be prevented from being offset. Then, the capping assembly can be contacted with the PCR tube so that the placed tube cap can be squeezed into the PCR tube. When the sealing depth of the tube cap needs to be adjusted, the capping assembly can be rotated to release the fixation of the capping assembly, and then the capping assembly can be moved upward or downward to adjust the contact distance between the capping assembly and the PCR tube, and then the fixing part can be re-transferred into the capping assembly to fix the capping assembly, so that the sealing depth of the tube cap can be adjusted. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 This is the overall structural diagram of the PCR tube capping device of the utility model;

[0017] Figure 2 This is a schematic diagram of the connection between the bottom plate and the mounting groove in the utility model;

[0018] Figure 3 This is a schematic diagram of the connection between the connecting block and the placement rack in the utility model;

[0019] Figure 4 This is a structural schematic diagram of the gland assembly in the utility model;

[0020] Figure 5 For this utility model Figure 4 Enlarged view of point A in .

[0021] In the figure, 1, base plate; 2, mounting groove; 3, connecting block; 4, placement frame; 5, adjustable telescopic rod; 6, pressure cover assembly; 601, square rod; 602, adjustment block; 603, fixing bolt; 604, positioning column; 605, annular block; 7, guide hole; 8, placement hole; 9, reinforcement rod; 10, threaded hole; 11, through hole; 12, limit rod; 13, positioning block; 14, rotating cover; 15, rubber sleeve. DETAILED DESCRIPTION

[0022] In order to make the purpose, technical solution and advantages of the utility model more clear, the utility model is further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described here are only used to explain the utility model and are not used to limit the utility model.

[0023] In the description of the present invention, it should be understood that the terms "length", "width", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside" and the like indicate positions or positional relationships based on the positions or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present invention. In addition, in the description of the present invention, "multiple" means two or more, unless otherwise clearly and specifically defined.

[0024] See also Figure 1-5 The utility model provides a technical solution: a PCR tube capping device, comprising a bottom plate 1, a mounting groove 2 is provided on the top of the bottom plate 1, a connecting block 3 is slidably connected to the inner wall of the mounting groove 2, a placing rack 4 is fixedly connected to the top of the connecting block 3, an adjusting telescopic rod 5 is fixedly connected to the left side of the bottom plate 1, an output end of the adjusting telescopic rod 5 passes through the bottom plate 1 and the mounting groove 2, and is fixedly connected to the left side of the connecting block 3, and a capping assembly 6 is fixedly connected to the rear side of the top of the bottom plate 1;

[0025] The pressure cover assembly 6 includes a square rod 601, the bottom of the square rod 601 is fixedly connected to the rear side of the top of the base plate 1, the surface of the square rod 601 is slidably connected to an adjusting block 602, the inner wall of the rear side of the adjusting block 602 is rotatably connected to a fixing bolt 603, the fixing bolt 603 passes through the adjusting block 602 and the square rod 601, and extends to the inner wall of the front side of the adjusting block 602, the front side of the adjusting block 602 is fixedly connected to a positioning column 604, and the surface of the positioning column 604 is rotatably connected to a ring block 605.

[0026] In this embodiment, by arranging the bottom plate 1, the mounting groove 2, the connecting block 3, the placement rack 4, the adjusting telescopic rod 5 and the pressure cover assembly 6, the PCR tube can be placed in the placement rack 4, and then the tube cover is placed at the PCR tube connection port, and then the adjusting telescopic rod 5 is started, so that the adjusting telescopic rod 5 can push the connecting block 3 under the fixation of the bottom plate 1, and the placement rack 4 can be driven to contact the lower part of the placed PCR tube and the pressure cover assembly 6 through the driving of the connecting block 3, and under the limitation of the mounting groove 2, the moving position of the connecting block 3 will not be affected. The capping assembly 6 is shifted, and then the capping assembly 6 is in contact with the PCR tube, so that the capping assembly 6 can squeeze the placed tube cap into the PCR tube. When the sealing depth of the tube cap needs to be adjusted, the capping assembly 6 can be rotated to release the fixation of the capping assembly 6, and then the capping assembly 6 is moved upward or downward to adjust the contact distance between the capping assembly 6 and the PCR tube, and then the fixing part can be transferred back into the capping assembly 6 to fix the capping assembly 6, so that the sealing depth of the tube cap can be adjusted.

[0027] As a technical optimization solution of the present invention, a guide hole 7 is opened on the left side of the bottom plate 1 . The guide hole 7 is circular, and the inner wall of the guide hole 7 contacts the output end of the adjustable telescopic rod 5 .

[0028] In this embodiment, by providing the guide hole 7, the guide hole 7 can assist in guiding the telescopic position of the output end of the telescopic rod 5, thereby avoiding deviation of the telescopic position of the output end of the telescopic rod 5.

[0029] As a technical optimization solution of the present utility model, a plurality of placement holes 8 are provided on the top of the placement rack 4 , and a plurality of placement holes 8 are provided in total and are evenly distributed on the top of the placement rack 4 .

[0030] In this embodiment, by providing the placement hole 8 , the placement hole 8 can assist in guiding the placement position of the PCR tube through the placement rack 4 .

[0031] As a technical optimization solution of the utility model, the inner wall of the placement rack 4 is fixedly connected with a reinforcement rod 9, and a total of four reinforcement rods 9 are provided, and the reinforcement rods 9 are inclined.

[0032] In this embodiment, by providing the reinforcement rod 9 , the reinforcement rod 9 can be used to reinforce the placement rack 4 , thereby increasing the use stability of the placement rack 4 .

[0033] As a technical optimization solution of the utility model, a threaded hole 10 is opened on the front side of the square rod 601 , and there are a total of several threaded holes 10 , and the threaded patterns on the inner walls of the threaded holes 10 mesh with the threaded patterns on the surface of the fixing bolt 603 .

[0034] In this embodiment, the threaded hole 10 is provided so that the threaded hole 10 can be used to fix the adjustment block 602 by cooperating with the fixing bolt 603 and the square rod 601 , thereby improving the use stability of the adjustment block 602 .

[0035] As a technical optimization solution of the utility model, a through hole 11 is opened on the top of the adjustment block 602, and the inner wall of the through hole 11 is slidably connected to a limit rod 12, and the bottom of the limit rod 12 is fixedly connected to the rear side of the top of the base plate 1.

[0036] In this embodiment: by setting the through hole 11 and the limiting rod 12, the through hole 11 can cooperate with the limiting rod 12 to limit the position of the adjustment block 602 during movement, thereby avoiding the position of the adjustment block 602 from being offset during movement.

[0037] As a technical optimization solution of the present invention, the other end of the positioning column 604 is fixedly connected to a positioning block 13 used in conjunction with it, and the rear side of the positioning block 13 contacts the front side of the annular block 605 .

[0038] In this embodiment, by setting the positioning block 13, the positioning block 13 can limit the annular block 605 through the fixation of the positioning column 604 to prevent the position of the annular block 605 from shaking and shifting.

[0039] As a technical optimization solution of the present invention, a rotating cover 14 used in conjunction with the fixing bolt 603 is fixedly connected to the surface thereof, and a rubber sleeve 15 is fixedly connected to the surface of the rotating cover 14 .

[0040] In this embodiment: by providing the rotating cover 14 and the rubber sleeve 15, the rotating cover 14 can be connected with the fixing bolt 603 through the provision of the rotating cover 14 and the rubber sleeve 15, so that when the rotating cover 14 is rotated, the fixing bolt 603 is driven to rotate, thereby improving the rotation convenience of the fixing bolt 603, and through the provision of the rubber sleeve 15, the rubber sleeve 15 can increase the friction force when the rotating cover 14 is rotated, thereby avoiding slipping of the hand when the rotating cover 14 is rotated.

[0041] Working principle: First, put the PCR tube into the placement rack 4, and then put the tube cover on the PCR tube connection port, and then start the adjustable telescopic rod 5, so that the adjustable telescopic rod 5 can push the connection block 3 under the fixation of the bottom plate 1, and through the drive of the connection block 3, the placement rack 4 and the placed PCR tube can be driven to contact the bottom of the annular block 605, and when the PCR tube continues to move, the annular block 605 can squeeze the tube cover into the PCR tube, and by adjusting the telescopic performance of the telescopic rod 5, when the placement rack 4 is reset through the connection block 3, the sealed PCR tube can be driven to perform secondary squeezing and sealing. When the sealing depth of the tube cover needs to be adjusted, the fixing bolt 603 can be rotated, and after the fixing bolt 603 is taken out, the adjusting block 602 can be moved upward or downward, and when the adjusting block 602 moves, the positioning column 604 can be driven to move, and then the position of the annular block 605 can be adjusted by the positioning column 604, so that the sealing depth of the tube cover can be adjusted, and after moving to the desired position, the fixing bolt 603 can be reinserted, so that the adjusted adjusting block 602 can be fixed, and then the tube cover can be pressed.

[0042] The above are only preferred embodiments of the present invention and are not intended to limit the present invention. Any modifications, equivalent substitutions and improvements made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A PCR tube capping device, comprising a bottom plate (1), characterized in that: The top of the base plate (1) is provided with a mounting groove (2), the inner wall of the mounting groove (2) is slidably connected to a connecting block (3), the top of the connecting block (3) is fixedly connected to a placing frame (4), the left side of the base plate (1) is fixedly connected to an adjustable telescopic rod (5), the output end of the adjustable telescopic rod (5) passes through the base plate (1) and the mounting groove (2), and is fixedly connected to the left side of the connecting block (3), and the rear side of the top of the base plate (1) is fixedly connected to a pressure cover assembly (6); The pressure cover assembly (6) comprises a square rod (601), the bottom of the square rod (601) is fixedly connected to the rear side of the top of the base plate (1), the surface of the square rod (601) is slidably connected to an adjustment block (602), the inner wall of the rear side of the adjustment block (602) is rotatably connected to a fixing bolt (603), the fixing bolt (603) passes through the adjustment block (602) and the square rod (601), and extends to the inner wall of the front side of the adjustment block (602), the front side of the adjustment block (602) is fixedly connected to a positioning column (604), and the surface of the positioning column (604) is rotatably connected to a ring block (605).

2. A PCR tube capping device according to claim 1, characterized in that: A guide hole (7) is provided on the left side of the bottom plate (1); the guide hole (7) is circular, and the inner wall of the guide hole (7) contacts the output end of the adjustable telescopic rod (5).

3. A PCR tube capping device according to claim 1, characterized in that: The top of the placement rack (4) is provided with a plurality of placement holes (8), and the placement holes (8) are provided in a plurality and are evenly distributed on the top of the placement rack (4).

4. A PCR tube capping device according to claim 1, characterized in that: The inner wall of the placement rack (4) is fixedly connected with a reinforcement rod (9), and a total of four reinforcement rods (9) are provided, and the reinforcement rods (9) are inclined.

5. A PCR tube capping device according to claim 1, characterized in that: A threaded hole (10) is provided on the front side of the square rod (601), and a plurality of threaded holes (10) are provided. The threaded patterns on the inner walls of the threaded holes (10) mesh with the threaded patterns on the surfaces of the fixing bolts (603).

6. A PCR tube capping device according to claim 1, characterized in that: A through hole (11) is provided on the top of the adjustment block (602); a limit rod (12) is slidably connected to the inner wall of the through hole (11); and the bottom of the limit rod (12) is fixedly connected to the rear side of the top of the base plate (1).

7. A PCR tube capping device according to claim 1, characterized in that: The other end of the positioning column (604) is fixedly connected to a positioning block (13) used in conjunction with it, and the rear side of the positioning block (13) is in contact with the front side of the annular block (605).

8. A PCR tube capping device according to claim 1, characterized in that: The surface of the fixing bolt (603) is fixedly connected to a rotating cover (14) used in conjunction with the fixing bolt (603), and the surface of the rotating cover (14) is fixedly connected to a rubber sleeve (15).