Special cotton ball box suitable for culturing NK cells
By introducing a mist spray mechanism into a special cotton ball box to maintain the volatile state of alcohol, the problem of poor wiping caused by alcohol volatility in the prior art is solved, and an effective cell cleaning and a safe NK cell culture environment is achieved.
Patent Information
- Application Number
- CN202421326001.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-06-11
- Publication Date
- 2025-02-07
- Estimated Expiration
- Not applicable · inactive patent
AI Technical Summary
In the existing special cotton ball box suitable for culturing NK cells, alcohol evaporates for a long time, resulting in the inability to effectively wipe the instrument when using cotton balls to wipe the instrument, causing cell contamination.
A special cotton ball box including a mist spray mechanism is designed. The alcohol in the liquid storage tank is extracted through a micro high-pressure water pump and sprayed onto the surface of the cotton ball through a mist nozzle to maintain the volatile state of the alcohol and ensure that the cotton ball is used every time. All full of alcohol.
It effectively avoids the problem that cotton balls cannot be effectively wiped during use, prevents cell contamination, and ensures the clean and safe NK cell culture environment.
Smart Images
Figure CN222432948U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field related to NK cells, in particular to a special cotton ball box suitable for culturing NK cells. Background Art
[0002] The full name of NK cells is natural killer cells. It is an important immune cell and part of the innate immune system. NK cells can directly detect and kill virus-infected cells and tumor cells without prior sensitization or the help of other cells. Therefore, they play an important role in anti-viral infection and anti-tumor immunity. When culturing NK cells, cotton balls with alcohol in a special cotton ball box are needed to wipe the instruments used. Therefore, a special cotton ball box suitable for culturing NK cells is particularly needed.
[0003] However, the alcohol in the existing special cotton ball boxes for culturing NK cells will evaporate over time, which may cause the scissors, tweezers, pipettes, and the edges of the culture medium required for culturing NK cells to be unable to be effectively wiped, resulting in cell contamination. Utility Model Content
[0004] The purpose of the utility model is to provide a special cotton ball box suitable for culturing NK cells, so as to solve the problem that the alcohol in the existing special cotton ball box suitable for culturing NK cells proposed in the above-mentioned background technology will evaporate over a long period of time, which may easily lead to the problem that when the scissors, tweezers, pipettes, and the edges of the culture medium required in the process of culturing NK cells are wiped with cotton balls, they cannot be effectively wiped, resulting in cell contamination.
[0005] To achieve the above object, the utility model provides the following technical solutions: a special cotton ball box suitable for culturing NK cells, comprising a cotton ball box body, a cotton ball placement block is embedded in the cotton ball box body, a box cover is hingedly connected to one side of the surface of the cotton ball box body, a control switch is connected to the surface of the cotton ball box body, a mist spray mechanism is arranged inside the cotton ball box body, and a filtrate mechanism is arranged inside the cotton ball box body;
[0006] The mist spray mechanism includes a liquid storage block, a placement groove, a rechargeable battery, a micro high-pressure water pump, a liquid storage tank, a mist nozzle, a water pipe, a liquid inlet pipe and a first liquid discharge pipe. The inner side of the cotton ball box body is connected to the liquid storage block, the surface of the cotton ball placement block is provided with a placement groove, the surface of the cotton ball placement block is embedded with a rechargeable battery, the surface of the cotton ball placement block is embedded with a micro high-pressure water pump, the surface of the cotton ball placement block is embedded with a liquid storage tank, the surface of the liquid storage block is sealed and connected with a mist nozzle, one side of the surface of the liquid storage block is connected to the water pipe, one side of the surface of the liquid storage tank is connected to the liquid inlet pipe, and one side of the surface of the liquid storage tank is connected to the first liquid discharge pipe.
[0007] Preferably, the liquid storage block is a hollow structure, and the rechargeable battery is embedded in the placement groove.
[0008] Preferably, six groups of the mist nozzles are provided, and the mist nozzles are distributed at equal intervals.
[0009] Preferably, one end of the micro high-pressure water pump is sealed and connected to the liquid storage tank, and one end of the water pipe is sealed and connected to the micro high-pressure water pump.
[0010] Preferably, the filtrate mechanism includes a second drain pipe, a block, a filter, a limit groove and a handle, one side of the surface of the cotton ball box body is connected to the second drain pipe, the inner side of the cotton ball box body is connected to the block, the surface of the block is connected to the filter, the surface of the block is provided with a limit groove, and the surface of the filter is connected to the handle.
[0011] Preferably, one side of the surface of the filter screen matches the size of the blocks, and the blocks are provided in two groups.
[0012] Compared with the prior art, the beneficial effect of the utility model is that the special cotton ball box suitable for culturing NK cells only needs to press the control switch, and then the micro high-pressure water pump will extract the alcohol in the liquid storage tank and spray the alcohol in mist form, so that the alcohol that is continuously evaporated from the cotton ball will be re-attached to the alcohol, effectively avoiding the situation that the cotton ball cannot effectively wipe the scissors, tweezers, pipettes, and the edges of the culture fluid required in the process of culturing NK cells when used next time, resulting in cell contamination. BRIEF DESCRIPTION OF THE DRAWINGS
[0013] Figure 1 This is a schematic diagram of the side view of the appearance structure of the utility model;
[0014] Figure 2 This is a schematic diagram of the exploded structure of the mist spray mechanism of the utility model;
[0015] Figure 3 This is a schematic diagram of the decomposed structure of the filtration mechanism of the utility model;
[0016] Figure 4 For this utility model Figure 3 Enlarged structural diagram at A in the middle.
[0017] In the figure: 1. cotton ball box body; 2. cotton ball placement block; 3. box cover; 4. control switch; 5. mist spray mechanism; 501. liquid storage block; 502. placement slot; 503. rechargeable battery; 504. micro high-pressure water pump; 505. liquid storage tank; 506. mist nozzle; 507. water pipe; 508. liquid inlet pipe; 509. first liquid discharge pipe; 6. filtrate mechanism; 601. second liquid discharge pipe; 602. block; 603. filter screen; 604. limit slot; 605. handle. DETAILED DESCRIPTION
[0018] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.
[0019] See also Figure 1-4 The utility model provides a technical solution: a special cotton ball box suitable for culturing NK cells, comprising a cotton ball box body 1, a cotton ball placement block 2 is embedded in the cotton ball box body 1, a box cover 3 is hingedly connected to one side of the surface of the cotton ball box body 1, a control switch 4 is connected to the surface of the cotton ball box body 1, a mist spray mechanism 5 is arranged inside the cotton ball box body 1, and a filtrate mechanism 6 is arranged inside the cotton ball box body 1;
[0020] The mist spray mechanism 5 includes a liquid storage block 501, a placement groove 502, a rechargeable battery 503, a micro high-pressure water pump 504, a liquid storage tank 505, a mist nozzle 506, a water pipe 507, a liquid inlet pipe 508 and a first liquid discharge pipe 509. The inner side of the cotton ball box body 1 is connected with the liquid storage block 501, the surface of the cotton ball placement block 2 is provided with a placement groove 502, the surface of the cotton ball placement block 2 is embedded with a rechargeable battery 503, the surface of the cotton ball placement block 2 is embedded with a micro high-pressure water pump 504, the surface of the cotton ball placement block 2 is embedded with a liquid storage tank 505, the surface of the liquid storage block 501 is sealed and connected with the mist nozzle 506, the surface of the liquid storage block 501 is connected with a water pipe 507, the surface of the liquid storage tank 505 is connected with a liquid inlet pipe 508, and the surface of the liquid storage tank 505 is connected with a first liquid discharge pipe 509. When spraying alcohol on the ball surface, first press the control switch 4, then press the control switch 4 to control the rechargeable battery 503 inside the placement slot 502 to provide power to the micro high-pressure water pump 504 to start it, and then the micro high-pressure water pump 504 draws the alcohol inside the liquid storage tank 505 into its interior, and then the micro high-pressure water pump 504 sends the alcohol inside it to the interior of the liquid storage block 501 through the water pipe 507. When the alcohol inside the liquid storage block 501 is full and reaches a certain pressure, the alcohol is sprayed out in the form of mist through the mist nozzle 506. At this time, the misted alcohol will fall on the surface of the cotton ball, making its surface full of alcohol liquid. When the alcohol inside the liquid storage tank 505 needs to be replaced, the remaining alcohol can be discharged through the first drain pipe 509, and then the alcohol can be injected into the interior of the liquid storage tank 505 through the liquid inlet pipe 508.
[0021] Furthermore, the liquid storage block 501 is a hollow structure, and the rechargeable battery 503 is embedded in the placement groove 502. Through the setting of the rechargeable battery 503, when in use, the rechargeable battery 503 can provide power for the micro high-pressure water pump 504. At the same time, when the rechargeable battery 503 is out of power, it can be charged without replacement.
[0022] Furthermore, six groups of mist nozzles 506 are provided, and the mist nozzles 506 are distributed at equal intervals. Through the setting of the mist nozzles 506, when in use, the mist nozzles 506 can spray alcohol in the form of mist, and then the alcohol will adhere to the surface of the cotton ball, thereby effectively avoiding the situation where the alcohol on the surface of the cotton ball evaporates and the cotton ball cannot be used.
[0023] Furthermore, one end of the micro high-pressure water pump 504 is sealed and connected to the liquid storage tank 505, and one end of the water pipe 507 is sealed and connected to the micro high-pressure water pump 504. Through the setting of the water pipe 507, when in use, the water pipe 507 can deliver the alcohol pumped out by the micro high-pressure water pump 504 into the interior of the liquid storage block 501 to facilitate subsequent alcohol spraying.
[0024] Furthermore, the filtrate mechanism 6 includes a second liquid discharge pipe 601, a block 602, a filter screen 603, a limiting groove 604 and a handle 605. One side of the surface of the cotton ball box body 1 is connected to the second liquid discharge pipe 601, and the inner side of the cotton ball box body 1 is connected to the block 602. The surface of the block 602 is connected to the filter screen 603. The surface of the block 602 is provided with a limiting groove 604, and the surface of the filter screen 603 is connected to the handle 605. Through the arrangement of the second liquid discharge pipe 601, the block 602, the filter screen 603, the limiting groove 604 and the handle 605, when in use First, use tweezers to pick up the cotton ball in the cotton ball placement block 2, then squeeze out the alcohol in the cotton ball on the filter 603, and use the cotton ball to wipe the scissors, tweezers, pipettes, and the edges of the culture medium required in the process of culturing NK cells. The squeezed alcohol can be discharged through the second drain pipe 601. When the filter 603 needs to be taken out, just move the handle 605. At this time, one side of the filter 603 is constantly separated from the limiting groove 604 on the surface of the block 602 until one side of the filter 603 is completely separated from the limiting groove 604, and then the filter 603 can be taken out.
[0025] Furthermore, one side of the surface of the filter 603 is consistent with the size of the block 602. The block 602 is provided with two groups. Through the setting of the filter 603, when the cotton ball squeezes the filter 603 during use, the alcohol in the cotton ball will be squeezed out by the filter 603, which is more convenient for wiping the scissors, tweezers, pipettes, and the edges of the culture fluid required in the process of culturing NK cells.
[0026] Working principle: First, when it is necessary to spray alcohol on the surface of the cotton ball, first press the control switch 4, then press the control switch 4 to control the rechargeable battery 503 inside the placement slot 502 to provide power to the micro high-pressure water pump 504 to start it, and then the micro high-pressure water pump 504 draws the alcohol inside the liquid storage tank 505 into its interior, and then the micro high-pressure water pump 504 sends the alcohol inside it to the interior of the liquid storage block 501 through the water pipe 507. When the alcohol inside the liquid storage block 501 is full and reaches a certain pressure, the alcohol is sprayed out in the form of mist through the mist nozzle 506. At this time, the misted alcohol will fall on the surface of the cotton ball, making its surface full of alcohol liquid. When the alcohol inside the liquid storage tank 505 needs to be replaced, it can be replaced by The remaining alcohol is first discharged through the first liquid discharge pipe 509, and then the alcohol is injected into the liquid storage tank 505 through the liquid inlet pipe 508. When cotton balls are needed later, use tweezers to pick up the cotton balls in the cotton ball placement block 2, and then squeeze out the alcohol in the cotton balls on the filter 603. The scissors, tweezers, pipettes, and the edges of the culture fluid required in the process of culturing NK cells can be wiped with the cotton balls. The squeezed alcohol can be discharged through the second liquid discharge pipe 601. When the filter 603 needs to be taken out later, only the handle 605 needs to be moved. At this time, one side of the filter 603 is constantly separated from the limiting groove 604 on the surface of the block 602 until one side of the filter 603 is completely separated from the limiting groove 604, and then the filter 603 can be taken out.
[0027] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.
Claims
1. A special cotton ball box suitable for culturing NK cells, comprising a cotton ball box body (1), characterized in that: A cotton ball placement block (2) is embedded in the cotton ball box (1), a cover (3) is hingedly connected to one side of the surface of the cotton ball box (1), a control switch (4) is connected to the surface of the cotton ball box (1), a mist spray mechanism (5) is arranged inside the cotton ball box (1), and a filtration mechanism (6) is arranged inside the cotton ball box (1); The mist spray mechanism (5) comprises a liquid storage block (501), a placement groove (502), a rechargeable battery (503), a micro high-pressure water pump (504), a liquid storage tank (505), a mist nozzle (506), a water pipe (507), a liquid inlet pipe (508) and a first liquid discharge pipe (509); the liquid storage block (501) is connected to one side of the interior of the cotton ball box (1); the placement groove (502) is provided on the surface of the cotton ball placement block (2); and the rechargeable battery (503) is embedded on the surface of the cotton ball placement block (2). A pool (503) is provided, a micro high-pressure water pump (504) is embedded on the surface of the cotton ball placement block (2), a liquid storage tank (505) is embedded on the surface of the cotton ball placement block (2), a mist nozzle (506) is sealed on the surface of the liquid storage block (501), a water pipe (507) is connected to one side of the surface of the liquid storage block (501), a liquid inlet pipe (508) is connected to one side of the surface of the liquid storage tank (505), and a first liquid discharge pipe (509) is connected to one side of the surface of the liquid storage tank (505).
2. A special cotton ball box suitable for culturing NK cells according to claim 1, characterized in that: The liquid storage block (501) is a hollow structure, and the rechargeable battery (503) is embedded in the placement groove (502).
3. A special cotton ball box suitable for culturing NK cells according to claim 1, characterized in that: The mist nozzles (506) are arranged in six groups, and the mist nozzles (506) are distributed at equal intervals.
4. A special cotton ball box suitable for culturing NK cells according to claim 1, characterized in that: One end of the micro high-pressure water pump (504) is sealedly connected to the liquid storage tank (505), and one end of the water pipe (507) is sealedly connected to the micro high-pressure water pump (504).
5. A special cotton ball box suitable for culturing NK cells according to claim 1, characterized in that: The filtrate mechanism (6) comprises a second liquid discharge pipe (601), a block (602), a filter screen (603), a limit groove (604) and a handle (605); one side of the surface of the cotton ball box body (1) is connected to the second liquid discharge pipe (601); one side of the interior of the cotton ball box body (1) is connected to the block (602); the surface of the block (602) is connected to the filter screen (603); the surface of the block (602) is provided with a limit groove (604); and the surface of the filter screen (603) is connected to the handle (605).
6. A special cotton ball box suitable for culturing NK cells according to claim 5, characterized in that: One side of the surface of the filter screen (603) matches the size of the blocks (602), and the blocks (602) are provided in two groups.