Cell extraction device for cell experiment
By designing a cell extraction device including active crushing rollers, driven crushing rollers, transmission gears, screens, feeding components and grinding components, the problem of inadequate crushing of tissue samples in the prior art is solved, and automatic crushing and Screening and meticulous grinding improve experimental efficiency and accuracy.
Patent Information
- Application Number
- CN202420776249.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-04-15
- Publication Date
- 2025-02-11
- Estimated Expiration
- 2034-04-15
AI Technical Summary
When existing cell extraction devices break up tissue samples, they often fail to break into place, resulting in manual screening and re-molding, which is cumbersome and cannot be finely ground.
A cell extraction device including an active crushing roller, a driven crushing roller, a transmission gear, a screen, a feed assembly and a grinding assembly are designed. The tissue samples are crushed by driving the gear to crush the crushing roller. The screen screens are screened with qualified and unqualified samples. The feeding assembly is automatically refilled and crushed, and the grinding assembly is carefully ground.
Automatic tissue sample crushing and screening is achieved, reducing manual intervention, allowing more detailed grinding of samples, and improving experimental efficiency and accuracy.
Smart Images
Figure CN222446774U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of cell experiments, in particular to a cell extraction device used for cell experiments. Background Art
[0002] Cell isolation and extraction refers to the process of isolating target cells from a mixed cell population and purifying or extracting them. In the study of biology and life sciences, cell isolation and extraction is a common experimental technique used to study the characteristics, functions and molecular mechanisms of specific cell types. Cell isolation and extraction can be applied to different types of samples, including tissue samples, cell cultures and biological fluids. Tissue samples are often separated into small cell blocks or cell suspensions by mechanical means such as cutting, crushing and grinding.
[0003] At present, many cell extraction devices often fail to fully crush tissue samples, resulting in large pieces of tissue that need to be manually screened and then crushed again, which is troublesome and cannot grind the tissue samples more finely. Utility Model Content
[0004] In view of the above-mentioned deficiencies in the prior art, the utility model provides a cell extraction device for cell experiments to solve the problems raised in the above-mentioned background technology.
[0005] In order to achieve the above-mentioned purpose of the utility model, the technical solution adopted by the utility model is a cell extraction device for cell experiments, including a box body, a first motor is installed on the outer wall of one side of the box body, the output shaft end of the first motor extends into the box body and is fixedly connected to an active crushing roller, the other end of the active crushing roller is rotatably connected to the inner wall of the other side of the box body, and a driven crushing roller is also rotatably connected between the inner walls of the two sides of the box body, one end of the active crushing roller and the driven crushing roller are fixedly sleeved with a transmission gear, and the two transmission gears are meshed with each other, a fixed frame is fixedly provided inside the box body and below the active crushing roller and the driven crushing roller, a screen is provided in the fixed frame, a feeding assembly is provided on the outer wall of the box body on the side away from the first motor, and a grinding assembly is also provided inside the box body.
[0006] As an improvement: the material feeding assembly includes a conveying cylinder, a second motor, a material feeding auger, a material receiving hopper and a return hopper. The conveying cylinder is fixedly connected to the outer wall of the box body away from the first motor, and the second motor is installed on the bottom wall of the conveying cylinder. The output shaft end of the second motor extends into the conveying cylinder and is fixedly connected to the material feeding auger. The upper end of the material feeding auger is rotatably connected to the upper inner wall of the conveying cylinder. A material receiving hopper is fixedly connected to the inner wall of the box body close to the conveying cylinder and below the screen, and a return hopper is fixedly connected to the upper part of the cylinder body of the conveying cylinder.
[0007] As an improvement: the grinding assembly includes a grinding table, a grinding groove, a third motor, a rotating rod and a grinding cone. The grinding table is fixedly connected inside the box and below the screen. The grinding table is provided with a grinding groove. The third motor is installed at the center of the lower inner wall of the box. The output shaft end of the third motor is fixedly connected to the rotating rod. The upper end of the rotating rod extends into the grinding groove and is fixedly connected to the grinding cone.
[0008] As an improvement: a vibration motor is installed on the lower side wall of the screen.
[0009] As an improvement: a feeding hopper is fixedly connected to the upper outer wall of the box body.
[0010] As an improvement: a blanking plate is provided inside the box and below the grinding table, and the rotating rod is rotatably plugged on the blanking plate.
[0011] Compared with the prior art, the utility model has the following beneficial effects:
[0012] 1. Through the feeding component, the insufficiently crushed tissue samples can be automatically returned and crushed again until the size is qualified. Screening and returning can be completed automatically without human intervention, saving manpower and being more convenient and practical. Through the grinding component, the crushed tissue samples can be ground more finely. BRIEF DESCRIPTION OF THE DRAWINGS
[0013] Figure 1 This is a schematic diagram of the overall structure of a cell extraction device used for cell experiments in the utility model;
[0014] Figure 2 This is a schematic diagram of the structure of an active crushing roller of a cell extraction device used in cell experiments of the utility model;
[0015] Figure 3 This is a cross-sectional view of a box of a cell extraction device used for cell experiments of the utility model;
[0016] As shown in the figure:
[0017] 1. Box body; 1.1. First motor; 1.2. Active crushing roller; 1.3. Driven crushing roller; 1.4. Transmission gear; 1.5. Fixed frame; 1.6. Screen; 2. Feeding assembly; 3. Grinding assembly; 2.1. Conveying cylinder; 2.2. Second motor; 2.3. Feeding auger; 2.4. Receiving hopper; 2.5. Return hopper; 3.1. Grinding table; 3.2. Grinding trough; 3.3. Third motor; 3.4. Rotating rod; 3.5. Grinding cone; 1.7. Vibration motor; 1.8. Feeding hopper; 1.9. Unloading plate. DETAILED DESCRIPTION
[0018] In order to make the technical means, creative features and purpose effects achieved by the present invention easy to understand, the present invention is further described below in conjunction with specific implementation methods.
[0019] In the description of the present invention, it should be noted that the terms "upper", "lower", "inner", "outer", "front", "rear", "both sides", "one side", "the other side" and the like indicate positions or positional relationships based on the positions or positional relationships shown in the drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operate in a specific orientation, and therefore cannot be understood as limiting the present invention. In addition, the terms "first" and "second" are used for descriptive purposes only and cannot be understood as indicating or implying relative importance.
[0020] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "provided with", "connected", etc. should be understood in a broad sense. For example, "connected" can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be an indirect connection through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.
[0021] like Figure 1 and Figure 2As shown, a cell extraction device for cell experiments comprises a box body 1, a first motor 1.1 is installed on one side outer wall of the box body 1, the output shaft end of the first motor 1.1 extends into the box body 1 and is fixedly connected with an active crushing roller 1.2, the other end of the active crushing roller 1.2 is rotatably connected to the other side inner wall of the box body 1, and a driven crushing roller 1.3 is also rotatably connected between the two side inner walls of the box body 1, one end of the active crushing roller 1.2 and the driven crushing roller 1.3 are fixedly sleeved with a transmission gear 1.4, the two transmission gears 1.4 are meshed, the output shaft of the first motor 1.1 can drive the active crushing roller 1.2 to rotate, under the action of the two transmission gears 1.4, the driven crushing roller 1.3 also rotates, and the active The crushing roller 1.2 and the driven crushing roller 1.3 rotate towards each other to crush the tissue sample. A fixed frame 1.5 is fixedly provided inside the box 1 and below the active crushing roller 1.2 and the driven crushing roller 1.3. A screen 1.6 is provided inside the fixed frame 1.5. The crushed tissue sample will fall on the screen 1.6. Since the upper side wall of the screen 1.6 is an inclined surface, when the screen 1.6 vibrates, the qualified small pieces of tissue samples will pass through the screen 1.6 and fall into the grinding groove 3.2, while the unqualified large pieces of tissue samples will approach the receiving hopper 2.4 during the vibration, and then fall into the receiving hopper 2.4. A feeding component 2 is provided on the outer wall of the box 1 on the side away from the first motor 1.1, and a grinding component 3 is also provided inside the box 1.
[0022] Specifically, Figure 3 As shown, a cell extraction device for cell experiments, the feeding assembly 2 includes a conveying cylinder 2.1, a second motor 2.2, a feeding auger 2.3, a receiving hopper 2.4 and a return hopper 2.5. The outer wall of the box body 1 away from the first motor 1.1 is fixedly connected with the conveying cylinder 2.1, the second motor 2.2 is installed on the bottom wall of the conveying cylinder 2.1, the output shaft end of the second motor 2.2 extends into the conveying cylinder 2.1 and is fixedly connected with the feeding auger 2.3, the upper end of the feeding auger 2.3 is rotatably connected to the upper inner wall of the conveying cylinder 2.1, and the inner wall of the box body 1 close to the conveying cylinder 2.1 and located at the screen 1.6 A receiving hopper 2.4 is fixedly connected to the bottom, and a return hopper 2.5 is fixedly connected to the upper part of the cylinder body of the conveying cylinder 2.1. The large tissue samples entering the receiving hopper 2.4 will enter the conveying cylinder 2.1. The output shaft of the second motor 2.2 can drive the feeding auger 2.3 to rotate. When the feeding auger 2.3 rotates, the tissue samples entering the conveying cylinder 2.1 can be transported upward. When transported to the upper part of the conveying cylinder 2.1, the tissue samples will pass through the return hopper 2.5 and enter the box body 1 again for crushing until the crushing is qualified. Screening and returning materials can be automatically completed without human intervention, saving manpower and being more convenient and practical.
[0023] Specifically, Figure 3As shown, a cell extraction device for cell experiments, the grinding assembly 3 includes a grinding table 3.1, a grinding groove 3.2, a third motor 3.3, a rotating rod 3.4 and a grinding cone 3.5. The grinding table 3.1 is fixedly connected to the inside of the box 1 and below the screen 1.6. The grinding table 3.1 is provided with a grinding groove 3.2. The third motor 3.3 is installed at the center of the lower inner wall of the box 1. The output shaft end of the third motor 3.3 is fixedly connected to the rotating rod 3.4. The upper end of the rotating rod 3.4 extends into the grinding groove 3.2 and is fixedly connected to the grinding cone 3.5. The output shaft of the third motor 3.3 can drive the rotating rod 3.4 to rotate. When the rotating rod 3.4 rotates, it will drive the grinding cone 3.5 to rotate. The rotation of the grinding cone 3.5 will grind the tissue sample falling into the grinding groove 3.2 and grind the tissue sample into finer particles.
[0024] Specifically, Figure 3 As shown, a cell extraction device for cell experiments is provided, wherein a vibration motor 1.7 is installed on the lower side wall of the screen 1.6, and the vibration motor 1.7 can drive the screen 1.6 to vibrate.
[0025] Specifically, Figure 3 As shown, a cell extraction device for cell experiments, a feeding hopper 1.8 is fixedly connected to the upper outer wall of the box 1, and the tissue sample is added into the box 1 through the feeding hopper 1.8.
[0026] Specifically, Figure 3 As shown, a cell extraction device for cell experiments is provided, inside the box 1 and below the grinding table 3.1, a feed plate 1.9 is provided, the feed plate 1.9 is inclined, and the fine particles produced during grinding fall on the feed plate 1.9 and are discharged from the box 1, and the rotating rod 3.4 is rotatably plugged into the feed plate 1.9.
[0027] During the specific implementation of the utility model, the tissue sample is added into the box body 1 through the feeding hopper 1.8, the output shaft of the first motor 1.1 can drive the active crushing roller 1.2 to rotate, and under the action of the two transmission gears 1.4, the driven crushing roller 1.3 also rotates, and the active crushing roller 1.2 and the driven crushing roller 1.3 rotate in opposite directions to crush the tissue sample, and the crushed tissue sample will fall on the screen 1.6, and the vibration motor 1.7 drives the screen 1.6 to vibrate. Since the upper side wall of the screen 1.6 is an inclined surface, during the vibration, the small pieces of tissue samples that are qualified in crushing will pass through the screen 1.6 and fall into the grinding groove 3.2, while the large pieces of tissue samples that are unqualified will approach the receiving hopper 2.4 during the vibration, and then fall into the receiving hopper 2.4. The large pieces of tissue samples that enter the receiving hopper 2.4 will enter In the conveying cylinder 2.1, the output shaft of the second motor 2.2 can drive the feeding auger 2.3 to rotate. When the feeding auger 2.3 rotates, the tissue sample entering the conveying cylinder 2.1 can be transported upward. When it is transported to the upper part of the conveying cylinder 2.1, the tissue sample will pass through the return hopper 2.5 and enter the box 1 again for crushing until it is qualified. No human intervention is required, and screening and returning can be automatically completed, which saves manpower and is more convenient and practical. The output shaft of the third motor 3.3 can drive the rotating rod 3.4 to rotate. When the rotating rod 3.4 rotates, it will drive the grinding cone 3.5 to rotate. The rotation of the grinding cone 3.5 will grind the tissue sample falling into the grinding groove 3.2, and grind the tissue sample into finer particles. The fine particles generated during grinding will fall on the unloading plate 1.9 and then be discharged from the box 1.
[0028] The above shows and describes the basic principle and main features of the utility model and the advantages of the utility model. Those skilled in the art should understand that the utility model is not limited by the above embodiments. The above embodiments and descriptions are only for explaining the principle of the utility model. Without departing from the spirit and scope of the utility model, the utility model may have various changes and improvements, which fall within the scope of the utility model to be protected. The scope of protection claimed by the utility model is defined by the attached claims and their equivalents.
Claims
1. A cell extraction device for cell experiments, comprising a housing (1), characterized in that: A first motor (1.1) is mounted on an outer wall of one side of the box (1); an output shaft end of the first motor (1.1) extends into the box (1) and is fixedly connected to an active crushing roller (1.2); the other end of the active crushing roller (1.2) is rotatably connected to an inner wall of the other side of the box (1); a driven crushing roller (1.3) is also rotatably connected between the inner walls of both sides of the box (1); one end of each of the active crushing roller (1.2) and the driven crushing roller (1.3) is fixedly sleeved with a transmission gear (1.4); the two transmission gears (1.4) are meshed with each other; and the interior of the box (1) is provided with a plurality of driven crushing rollers (1.3). A fixed frame (1.5) is fixedly provided below the active crushing roller (1.2) and the driven crushing roller (1.3), a screen (1.6) being provided inside the fixed frame (1.5), a feeding assembly (2) being provided on an outer wall of a side of the box body (1) away from the first motor (1.1), a grinding assembly (3) being further provided inside the box body (1), the feeding assembly (2) comprising a conveying cylinder (2.1), a second motor (2.2), a feeding auger (2.3), a receiving hopper (2.4) and a returning hopper (2.5), a conveying assembly (2) being fixedly connected to an outer wall of a side of the box body (1) away from the first motor (1.1), and a grinding assembly (3) being further provided inside the box body (1). The conveying cylinder (2.1) is provided with a second motor (2.2) mounted on the bottom wall of the conveying cylinder (2.1); the output shaft end of the second motor (2.2) extends into the conveying cylinder (2.1) and is fixedly connected to a feeding auger (2.3); the upper end of the feeding auger (2.3) is rotatably connected to the upper inner wall of the conveying cylinder (2.1); a receiving hopper (2.4) is fixedly connected to the inner wall of one side of the box body (1) close to the conveying cylinder (2.1) and located below the screen (1.6); a return hopper (2.5) is fixedly connected to the upper part of the cylinder body of the conveying cylinder (2.1); the grinding assembly (3) comprises a grinding A grinding table (3.1), a grinding groove (3.2), a third motor (3.3), a rotating rod (3.4) and a grinding cone (3.5); the grinding table (3.1) is fixedly connected inside the box (1) and below the screen (1.6); the grinding table (3.1) is provided with a grinding groove (3.2); a third motor (3.3) is installed at the center of the lower inner wall of the box (1); the output shaft end of the third motor (3.3) is fixedly connected to the rotating rod (3.4); the upper end of the rotating rod (3.4) extends into the grinding groove (3.2) and is fixedly connected to the grinding cone (3.5).
2. A cell extraction device for cell experiments according to claim 1, characterized in that: A vibration motor (1.7) is installed on the lower side wall of the screen (1.6).
3. A cell extraction device for cell experiments according to claim 1, characterized in that: A feeding hopper (1.8) is fixedly connected to the upper outer wall of the box body (1).
4. A cell extraction device for cell experiments according to claim 1, characterized in that: A blanking plate (1.9) is provided inside the box (1) and below the grinding table (3.1), and the rotating rod (3.4) is rotatably plugged into the blanking plate (1.9).