Pathological tissue specimen storage device

By designing a pathological tissue specimen storage device with a double-layer filter and upper and lower split type, the problems of difficulty in sample extraction and contamination of fixative fluid in the prior art are solved, and efficient separation of tissue and fixative fluid and accurate specimen are achieved. The materials are taken to avoid environmental pollution.

CN222452946UActive Publication Date: 2025-02-11JILIN JINYU MEDICAL SCI INSPECTION CO LTD
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Patent Information

Application Number
CN202421328071.X
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-06-12
Publication Date
2025-02-11
Estimated Expiration
2034-06-12

AI Technical Summary

Technical Problem

During the process of sample collection of existing specimen bags or specimen bottles, the amount of fixing liquid is too large, making it difficult to detect small specimens, and the fixing liquid of large specimen is prone to turbidity, affecting the sampling accuracy; at the same time, the specimen bags or specimen are prone to cause fixing liquid to contaminate the environment. .

Method used

A pathological tissue specimen storage device is designed, including a removable connection of the upper storage part and the lower storage part. A double-layer filter and an inclined liquid outlet are provided inside the lower storage part, and tissue is realized through the double-layer filter. The separation from the fixing liquid and the upper and lower split design and the relative rotation of the filter mesh are adjusted to meet the needs of specimens of different sizes.

Benefits of technology

It effectively realizes the separation of tissue and fixative fluid, improves the efficiency of doctors to obtain materials, avoids specimen omissions, and softly connects waste liquid buckets to ensure the effective collection of fixative fluid and avoids environmental pollution.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a pathological tissue specimen storage device. The pathological tissue specimen storage device comprises an upper storage split body and a lower storage split body which are detachably connected, a double-layer filter screen which is detachably connected is arranged in the lower storage split body, and the upper-layer filter screen and the lower-layer filter screen can rotate relatively, so that the first through holes in the upper-layer filter screen and the second through holes in the lower-layer filter screen are distributed in a staggered mode or partially coincide with each other or completely coincide with each other; an inclined face is arranged at the bottom end in the lower storage split body, and the lowest point of the inclined face communicates with a liquid outlet. According to the utility model, tissues and stationary liquid can be separated conveniently through the double-layer filter screen, so that the tissues are retained on the filter screen; meanwhile, through the split design of the storage device, tissues can be conveniently taken out, the sampling efficiency is improved, and specimen omission is avoided; through relative rotation of the double-layer filter screen, the size of the filter aperture can be adjusted so as to adapt to different tissue filtration requirements; in addition, after being filtered out, the stationary liquid can be flexibly connected with a waste liquid barrel, so that environmental pollution caused by leakage of the stationary liquid is avoided.
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Description

Technical Field

[0001] The utility model relates to the technical field of medical detection auxiliary operation devices, in particular to a pathological tissue specimen storage device. Background Art

[0002] The specimens sent by the pathology department include tissue specimens and cell specimens. Tissue specimens are human tissues and are closely related to surgery. Pathological tissue specimens are generally living tissues obtained through surgery, endoscopy, and coarse needle puncture, such as the appendix removed due to appendicitis, the gallbladder removed due to gallstones, and the colon, breast, and uterus removed due to tumors. Pathological tissue specimens need to be made into slices through complex pathological techniques. Pathologists make the final diagnosis of the disease based on the slices, combined with imaging changes and clinical history, and guide clinical treatment. Cytology specimens include puncture cell smears, urine, gynecological cervical cell specimens, joint fluid, cerebrospinal fluid, serous cavity effusion, etc. Fine needle aspiration smears, nipple discharge smears and other clinically prepared smears need to be immediately placed in 95% alcohol for fixation, such as thyroid puncture cell smears. Other cytology specimens should be sent to the pathology department in time for processing and made into cell slides after they are collected.

[0003] Specimens are the basic materials for pathological diagnosis and are very important. Specimens need to be fixed and processed in time after leaving the human blood supply to maintain the integrity of tissue structure, protein, cell DNA and RNA. Fixation is to preserve specimens so that all substances and genetic information in tissue cells can be preserved and consistent with the state of the specimen when it is alive. If the specimen is not fixed in time or inappropriately, it will cause tissue corruption, autolysis, loss of antigens and genetic materials. The damage to the specimen is irreversible and irreparable. First of all, it will affect the quality of the slices. The tissue structure is unclear under the microscope, and the cell morphology cannot be judged, resulting in difficult or impossible diagnosis. It will also affect the accuracy of immunohistochemistry and genetic testing results, not to mention the guiding value of precision treatment. Therefore, timely dissection and fixation, and sufficient fixation time of fixative are very important and are also the prerequisite for accurate diagnosis.

[0004] At present, most hospital laboratories and third-party in vitro testing institutions use specimen bags or specimen bottles for specimens. In order to maintain the stability of the structure, morphology and chemical composition of biological cell and tissue samples, specimen fixatives need to be added to the specimen bags or specimen bottles. These fixatives fully infiltrate specimens such as sliced ​​tissues to fully fix them. Then operations such as staining, embedding and slicing can be performed to observe and study biological tissue cells. In general, the fixative in the specimen bag or specimen bottle is 5-20 times the specimen tissue. For small specimen tissues (such as gastrointestinal endoscopy, biopsy, puncture and other tissues), a large amount of fixative will make it difficult for doctors to find small specimen tissues when taking samples, and it is even more difficult to remove tissues from a large amount of fixative. For large specimen tissues, the amount of fixative used is more, and due to the large volume of specimen tissues, this will cause the fixative to be more likely to become turbid, which is difficult to distinguish when taking samples, and then lead to the omission of small tissues containing lesions in large specimens, resulting in inaccurate sampling. In addition, during the specimen collection process, the integrated specimen bag or specimen bottle can easily cause the fixative to be taken out with the specimen and pollute the environment (the fixative often contains toxic reagents such as formaldehyde).

[0005] Therefore, it is necessary to improve and innovate the existing specimen bags or specimen bottles. Utility Model Content

[0006] The utility model provides a pathological tissue specimen storage device to solve the technical problems that specimens in existing specimen bags or specimen bottles are difficult to obtain, tissues are easily missed and the environment is easily polluted.

[0007] In order to achieve the above purpose, the utility model provides the following technical solutions:

[0008] The utility model provides a pathological tissue specimen storage device, comprising an upper storage part and a lower storage part that are detachably connected;

[0009] The bottom of the upper storage body is cylindrical and movably connected to the top of the lower storage body;

[0010] The lower storage body is provided with a detachably connected double-layer filter screen inside, wherein the first through holes on the upper filter screen and the second through holes on the lower filter screen have equal apertures and are distributed in the same manner, and the upper filter screen and the lower filter screen can rotate relative to each other, so that the first through holes on the upper filter screen and the second through holes on the lower filter screen are staggered, partially overlapped, or completely overlapped;

[0011] The inner bottom end of the lower storage body is provided with an inclined surface, and the lowest point of the inclined surface is connected with a liquid outlet.

[0012] Furthermore, in the above-mentioned pathological tissue specimen storage device, the lower storage body includes a first body and a second body that are detachably connected, the top of the first body is movably connected to the bottom of the upper storage body, and the bottom of the first body is movably connected to the second body.

[0013] Furthermore, in the above-mentioned pathological tissue specimen storage device, the upper filter is located in the first sub-body, and the lower filter is located in the second sub-body.

[0014] Furthermore, in the above-mentioned pathological tissue specimen storage device, the upper filter screen is bowl-shaped, and the first through hole on the upper filter screen is located on the bottom wall of the upper filter screen; the outer side of the top edge of the upper filter screen is covered with a first rubber pad, and the edge of the upper filter screen is clamped on the first clamping groove at the upper end of the first split body, and the upper filter screen is connected to the first split body by interference fit through the first rubber pad.

[0015] Furthermore, in the above-mentioned pathological tissue specimen storage device, the lower filter screen adopts a flat structure, the outer side of the edge of the lower filter screen is coated with a second rubber pad, the edge of the lower filter screen is clamped on the second clamping groove at the upper end of the second split body, and the lower filter screen is connected to the second split body by interference fit through the second rubber pad.

[0016] Furthermore, in the above-mentioned pathological tissue specimen storage device, a connecting rod is connected to one side of the lower filter screen, and the connecting rod passes through a third through hole on the side wall of the second split body and is connected to a paddle located outside the second split body, and a third rubber pad is installed in the third through hole for the connecting rod to pass through.

[0017] Furthermore, in the above-mentioned pathological tissue specimen storage device, the diameters of the first through hole and the second through hole are both 3 mm.

[0018] Furthermore, in the above-mentioned pathological tissue specimen storage device, the top of the upper storage body is bag-shaped and is provided with a zipper or a sealing strip for sealing.

[0019] Furthermore, in the above-mentioned pathological tissue specimen storage device, the top of the upper storage body is cylindrical and movably connected with an upper cover for sealing.

[0020] Furthermore, in the above-mentioned pathological tissue specimen storage device, the liquid outlet is closed by a cover or connected to a waste liquid bucket by a hose.

[0021] Compared with the prior art, the beneficial effects of the utility model are:

[0022] The pathological tissue specimen storage device provided by the utility model facilitates the separation of tissue and fixative through the design of a double-layer filter net, so that the tissue remains on the filter net; at the same time, the upper and lower split design of the storage device further facilitates the removal of tissue, improves the efficiency of doctors in obtaining specimens, and avoids missing specimens; through the relative rotation of the double-layer filter net, the filter aperture size can be adjusted to meet different tissue filtration requirements; in addition, after the fixative is filtered out through the double-layer filter net, it can be connected to a waste liquid barrel through a soft connection to ensure effective collection of the waste liquid and avoid environmental pollution caused by leakage of the fixative. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings required for use in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments recorded in the present utility model. For ordinary technicians in this field, other drawings can also be obtained based on these drawings.

[0024] Figure 1 A cross-sectional view of a pathological tissue specimen storage device provided in an embodiment of the utility model.

[0025] Figure 2 This is a front view of a pathological tissue specimen storage device provided in an embodiment of the utility model.

[0026] Figure 3 A side view of a pathological tissue specimen storage device provided in an embodiment of the utility model.

[0027] Figure 4 This is a front view of a pathological tissue specimen storage device provided by another embodiment of the utility model.

[0028] Description of reference numerals:

[0029] 1. Upper storage body; 2. Lower storage body; 3. Upper filter; 4. First through hole; 5. Lower filter; 6. Second through hole; 7. Inclined surface; 8. Liquid outlet; 9. First body; 10. Second body; 11. First rubber pad; 12. First slot; 13. Second rubber pad; 14. Second slot; 15. Connecting rod; 16. Third through hole; 17. Paddle; 18. Third rubber pad; 19. Sealing strip; 20. Upper cover; 21. Cover. DETAILED DESCRIPTION

[0030] In order to enable those skilled in the art to better understand the technical solution of the utility model, the utility model will be further described in detail below in conjunction with the accompanying drawings. The following embodiments are only specific embodiments cited in this application to illustrate the technical solution of the present application, rather than to limit it, and the scope of protection of the present application is not limited thereto. In the description of the utility model, it should be noted that the orientation or positional relationship indicated by the terms "inside" and "outside" is based on the orientation or positional relationship shown in the accompanying drawings, which is only for the convenience of describing the utility model and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the utility model.

[0031] The utility model provides a pathological tissue specimen storage device, see Figure 1 to Figure 4 As shown. It includes an upper storage part 1 and a lower storage part 2 which are detachably connected; wherein:

[0032] The bottom of the upper storage body 1 is cylindrical and is movably connected to the top of the lower storage body 2; the top of the upper storage body 1 is tubular and is movably connected to an upper cover 20 for sealing. Figure 1 to Figure 3 As shown. This design is an improvement on the specimen bottle. In another embodiment, the top of the upper storage body 1 is bag-shaped and is provided with a zipper or sealing strip 19 for sealing. Figure 4 This design is an improvement on the specimen bag.

[0033] The lower storage part 2 is provided with a detachably connected double-layer filter screen inside, wherein the first through hole 4 on the upper filter screen 3 and the second through hole 6 on the lower filter screen 5 have the same aperture and are distributed in the same manner, for example, the apertures of the first through hole 4 and the second through hole 6 are both 3 mm. The upper filter screen 3 and the lower filter screen 5 can rotate relative to each other, so that the first through hole 4 on the upper filter screen 3 and the second through hole 6 on the lower filter screen 5 are staggered, partially overlapped, or completely overlapped; when the first through hole 4 and the second through hole 6 are staggered, the aperture of the filter screen is completely exposed, and through the relative rotation of the double-layer filter screen, when the first through hole 4 and the second through hole 6 partially overlap, it is equivalent to reducing the filtration aperture of the double-layer filter screen, which can be applied to the separation of tissues and fixatives of specimens of different sizes, the tissues are retained on the filter screen, and the fixative reaches the bottom of the lower storage part 2 through the filter screen.

[0034] In order to ensure that the fixative flows out smoothly, the inner bottom end of the lower storage body 2 is provided with an inclined surface 7, and the lowest point of the inclined surface 7 is connected to a liquid outlet 8. The liquid outlet 8 is closed by a cover 21 or connected to a waste liquid bucket by a hose. When the pathological tissue specimen storage device needs to be stored or transported, the upper cover 20 or the zipper or the sealing strip 19 and the cover 21 are closed; when the pathological tissue specimen storage device needs to separate the tissue from the fixative, the cover 21 can be opened and connected to the waste liquid bucket by a hose to prevent the fixative from leaking and polluting the environment. In order to improve the filtration efficiency, the top of the upper storage body (1) can be pressurized. For example, for a bottle-type structure, open the upper cover 20 and connect a pressurizing device to pressurize; for a bag-type structure, when the zipper or the sealing strip 19 is closed, the filtration can be promoted by squeezing the upper liquid.

[0035] In order to facilitate the disassembly, installation, cleaning and replacement of the upper filter screen 3 and the lower filter screen 5, in a preferred embodiment, the lower storage sub-body 2 includes a detachably connected first sub-body 9 and a second sub-body 10, the top of the first sub-body 9 is movably connected to the bottom of the upper storage sub-body 1, and the bottom of the first sub-body 9 is movably connected to the second sub-body 10. The specific connection method can be threaded connection, and a sealing gasket can be provided at the connection. The upper filter screen 3 is located in the first sub-body 9, and the lower filter screen 5 is located in the second sub-body 10.

[0036] In order to facilitate the collection of materials after the fixed liquid is filtered out, in a preferred embodiment, the upper filter screen 3 is bowl-shaped, the tissue is located in the bowl, and the first through hole 4 on the upper filter screen 3 is located on the bottom wall of the upper filter screen 3; in order to improve the sealing and stability, the top edge of the upper filter screen 3 is coated with a first rubber pad 11 on the outside, and the edge of the upper filter screen 3 is clamped on the first clamping groove 12 at the upper end of the first split body 9. The upper filter screen 3 is connected to the first split body 9 through an interference fit through the first rubber pad 11. When the upper filter screen 3 is taken out, it can be pulled out with a little force based on the elasticity of the first rubber pad 11.

[0037] In order to fit the upper filter screen 3 tightly, in a preferred embodiment, the lower filter screen 5 adopts a flat plate structure, and the lower filter screen 5 is close to the bottom of the upper filter screen 3. In order to improve the sealing and stability, the outer side of the edge of the lower filter screen 5 is covered with a second rubber pad 13, and the edge of the lower filter screen 5 is clamped on the second clamping groove 14 at the upper end of the second split body 10. The lower filter screen 5 is connected to the second split body 10 through the second rubber pad 13 by interference fit. When the lower filter screen 5 is taken out, it can be pulled out with a little force based on the elasticity of the second rubber pad 13.

[0038] In order to facilitate the rotation of the lower filter screen 5 relative to the upper filter screen 3, and thus achieve the effect of adjusting the filtration aperture of the double-layer filter screen, in a preferred embodiment, a connecting rod 15 is connected to one side of the lower filter screen 5, and the connecting rod 15 passes through the third through hole 16 on the side wall of the second split body 10 and is connected to the toggle plate 17 located outside the second split body 10. For example, a connecting rod with a thread and a lower filter screen 5 with a screw hole can be used for connection. Alternatively, the connecting rod 15 and the toggle plate 17 are movably connected. When the lower filter screen 5 needs to be taken out, the connecting rod can be first unscrewed from the outside of the second split body 10 or only the toggle plate 17 can be removed, and then the lower filter screen 5 can be taken out from the second split body 10.

[0039] Specifically, the third through hole 16 is a long hole. During operation, by moving the toggle plate 17 left and right, the lower filter screen 5 can be rotated relative to the upper filter screen 3. In order to improve the airtightness, a third rubber pad 18 is installed in the third through hole 16 for the connecting rod 15 to pass through. The third rubber pad 18 has a straight opening, which ensures that the toggle plate 17 can move left and right while also playing a sealing role, and cooperates with the second rubber pad 13 to further improve the sealing effect.

[0040] The pathological tissue specimen storage device provided by the utility model is convenient for separating tissue from fixative through the design of a double-layer filter screen, so that the tissue remains on the filter screen; at the same time, the upper and lower split design of the storage device further facilitates tissue removal, improves the efficiency of doctors in obtaining specimens, and avoids missing specimens; the double-layer filter screen can rotate relative to each other, and the filter aperture size can be adjusted to meet different tissue filtration requirements; in addition, after the fixative is filtered out through the double-layer filter screen, it can be connected to a waste liquid barrel through a soft connection to ensure effective collection of the waste liquid and avoid environmental pollution caused by leakage of the fixative.

[0041] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device. In the absence of further restrictions, the elements defined by the sentence "comprise a ..." do not exclude the existence of other identical elements in the process, method, article or device including the elements.

[0042] The above-described embodiments are only specific implementation methods of the present application, which are used to illustrate the technical solutions of the present application, rather than to limit them. The protection scope of the present application is not limited thereto. Although the present application is described in detail with reference to the aforementioned embodiments, ordinary technicians in the field should understand that any technician familiar with the technical field can still modify the technical solutions recorded in the aforementioned embodiments within the technical scope disclosed in the present application, or can easily think of changes, or make equivalent replacements for some of the technical specialties therein; and these modifications, changes or replacements do not make the essence of the corresponding technical solutions deviate from the spirit and scope of the technical solutions of the embodiments of the present application. They should all be included in the protection scope of the present application. Therefore, the protection scope of the present application should be based on the protection scope of the claims.

Claims

1. A pathological tissue specimen storage device, characterized in that: It comprises an upper storage part (1) and a lower storage part (2) which are detachably connected; The bottom of the upper storage body (1) is cylindrical and is movably connected to the top of the lower storage body (2); The lower storage body (2) is provided with a detachably connected double-layer filter screen inside, wherein the first through holes (4) on the upper filter screen (3) and the second through holes (6) on the lower filter screen (5) have equal apertures and are distributed in the same manner, and the upper filter screen (3) and the lower filter screen (5) can rotate relative to each other so that the first through holes (4) on the upper filter screen (3) and the second through holes (6) on the lower filter screen (5) are staggered, partially overlapped, or completely overlapped; The inner bottom end of the lower storage body (2) is provided with an inclined surface (7), and the lowest point of the inclined surface (7) is connected to a liquid outlet (8).

2. A pathological tissue specimen storage device according to claim 1, characterized in that: The lower storage sub-body (2) comprises a first sub-body (9) and a second sub-body (10) which are detachably connected, the top of the first sub-body (9) being movably connected to the bottom of the upper storage sub-body (1), and the bottom of the first sub-body (9) being movably connected to the second sub-body (10).

3. A pathological tissue specimen storage device according to claim 2, characterized in that: The upper filter screen (3) is located in the first split body (9), and the lower filter screen (5) is located in the second split body (10).

4. A pathological tissue specimen storage device according to claim 3, characterized in that: The upper filter screen (3) is bowl-shaped, and the first through hole (4) on the upper filter screen (3) is located on the bottom wall of the upper filter screen (3); the outer side of the top edge of the upper filter screen (3) is covered with a first rubber pad (11), the edge of the upper filter screen (3) is clamped on the first clamping groove (12) at the upper end of the first split body (9), and the upper filter screen (3) is connected to the first split body (9) by interference fit through the first rubber pad (11).

5. A pathological tissue specimen storage device according to claim 3, characterized in that: The lower filter screen (5) adopts a flat plate structure, the outer side of the edge of the lower filter screen (5) is covered with a second rubber pad (13), the edge of the lower filter screen (5) is clamped on the second clamping groove (14) at the upper end of the second split body (10), and the lower filter screen (5) is connected to the second split body (10) by interference fit through the second rubber pad (13).

6. A pathological tissue specimen storage device according to claim 5, characterized in that: A connecting rod (15) is connected to one side of the lower filter screen (5); the connecting rod (15) passes through a third through hole (16) on the side wall of the second split body (10) and is connected to a paddle plate (17) located outside the second split body (10); a third rubber pad (18) is installed in the third through hole (16) for the connecting rod (15) to pass through.

7. A pathological tissue specimen storage device according to claim 1, characterized in that: The diameters of the first through hole (4) and the second through hole (6) are both 3 mm.

8. The pathological tissue specimen storage device according to claim 1, characterized in that: The top of the upper storage part (1) is bag-shaped and is provided with a zipper or a sealing strip (19) for sealing.

9. A pathological tissue specimen storage device according to claim 1, characterized in that: The top of the upper storage body (1) is cylindrical and is movably connected to an upper cover (20) for sealing.

10. The pathological tissue specimen storage device according to claim 1, characterized in that: The liquid outlet (8) is closed by a cover (21) or connected to a waste liquid bucket by a hose.