Stem cell culture device

Abstract

The utility model discloses a stem cell culture device which comprises a box body, sliding grooves, culture drawers, inserting rods and heat insulation plates, the four heat insulation plates are fixedly installed on the inner side of the box body in a vertical array mode, culture bins are formed in the top end of the inner side of the box body and between every two adjacent heat insulation plates, and the sliding grooves are formed in the inner side walls of the culture bins; the sliding grooves of every two adjacent culture bins are perpendicular to each other, sliding strips are fixedly installed on the left side wall and the right side wall of each culture drawer, a handle is fixedly installed in the center of the outer side wall of each culture drawer, the sliding strips are transversely and slidably connected with the inner sides of the sliding grooves, and a plurality of fixing holes are evenly formed in the bottom of the inner side of each culture drawer. The side wall of the culture bin is communicated with a ventilation pipe, and the other end of the ventilation pipe is communicated with the ventilation chamber; according to the stem cell culture device, the independent culture drawer is arranged for taking and placing, so that culture of other stem cells is not delayed, and the culture efficiency of the device is improved.

Description

Technical Field

[0001] The present application relates to the technical field of stem cell cultivation, and in particular to a stem cell cultivation device. Background Art

[0002] Stem cells are ideal target cells for gene therapy. They can create an environment for the subsequent stable expression of the target gene. Hematopoietic stem cells and mesenchymal stem cells can be used to rebuild the body's hematopoietic system and immune system. They can be used as a routine treatment for blood diseases such as leukemia and aplastic anemia, as well as immune system deficiency and hyperactivity diseases. Therefore, stem cells need to be cultured. The existing stem cell culture equipment is not convenient for controlling the temperature during culture, resulting in a low survival rate of the cultured stem cells.

[0003] Application No. 202220331669.9 discloses a layered stem cell cultivation device, including a box door, a storage drawer, a support plate, a heating lamp and an air outlet. By setting a support plate, a partition, a heating lamp and a cooling fan, the device can place the partitions and culture dishes in layers as needed when in use, and heat the interior by irradiation with the heating lamp. The partitions between each layer block the light and isolate the temperature so that the temperature of the winter layer can be different to a certain extent. The cooling fan of each layer can dissipate heat and lower the temperature when the temperature is too high, prevent the temperature from being too high, and facilitate control of the internal temperature.

[0004] However, in use, there are the following defects:

[0005] Although heating lamps are used to heat each layer individually to adjust the temperature, since the storage drawers on each layer share a common door for taking and placing, each layer will be exposed to the air after the door is opened, causing the temperature of the stem cells still in culture in the storage drawers to lose, which not only affects the survival of the stem cells, but also requires reheating, which wastes energy. Utility Model Content

[0006] The purpose of the present application is to provide a stem cell cultivation device, which solves the problem proposed in the background art that although a heating lamp is used to heat each layer individually to adjust the temperature, since the storage drawers on each layer share a common door for taking and placing, each layer will be exposed to the air after the door is opened, resulting in the temperature loss of the stem cells in the storage drawers still under cultivation, which not only affects the survival of the stem cells, but also requires reheating, which wastes energy.

[0007] To achieve the above-mentioned purpose, the present application provides the following technical solutions: a stem cell cultivation device, comprising a box body, a slide groove, a culture drawer, a plug rod and a heat insulation board, the inner side of the box body is fixedly installed with four heat insulation boards in a vertical array, a culture bin is provided at the inner top end of the box body and between two adjacent heat insulation boards, and a slide groove is provided at the inner wall of the culture bin, the slide grooves of the two adjacent culture bins are perpendicular to each other, the left and right side walls of the culture drawer are fixedly installed with slide bars, and a handle is fixedly installed at the center of the outer wall of the culture drawer, the slide bar is laterally slidably connected on the inner side of the slide groove, a number of fixing holes are evenly provided at the inner bottom of the culture drawer, a ventilation chamber is provided at the inner bottom of the box body, the side wall of the culture bin is connected with a ventilation pipe, and the other end of the ventilation pipe is connected with the ventilation chamber.

[0008] In this technical solution, the culture dish of stem cells is put into the culture drawer by pulling out the culture drawer, and then pushed back into the culture drawer. After the battery supplies power to the device, the control panel controls the heating lamps in each culture bin to heat the culture dish. Through the heat insulation board, culture drawer, slide groove and slide bar, the culture dish in a culture drawer can be taken out separately without affecting other culture dishes. Since each culture bin is separately provided with a culture drawer, the culture dish in which the culture drawer needs to be taken out only needs to be pulled out separately, and the heat in other culture bins will not be lost. In addition, the pulling and pulling directions of the culture drawers in the two adjacent culture bins are distributed on different side walls of the box body, so that multiple culture drawers can be operated at the same time. When taking and placing, the culture dish will not be blocked by a certain culture drawer, thereby improving the cultivation efficiency and taking and placing efficiency of the device. At the same time, the stability of the culture dish can be increased through the fixing holes, the placement tray and the insertion rod. When the culture drawer is pulled out, the culture dish is likely to slide in the culture drawer and may collide with other culture dishes, thereby causing damage. The culture dish is placed on the placement tray and the placement tray is inserted into the fixing hole, so that it remains in place when the culture drawer is pulled out and pushed back, thereby improving the stability of cultivation and the insertion position can be freely selected, thereby improving the utilization efficiency of space. Each culture bin is provided with a ventilation duct for heat dissipation. After the exhaust fan is started, air can be exhausted to the outside of the box to bring out the heat in the culture bin.

[0009] As an optional solution of the technical solution of the present application, a filter is detachably installed at the opening of the ventilation chamber, an exhaust fan is fixedly installed on the side wall of the box body outside the filter, and a battery is movably placed inside the ventilation chamber.

[0010] A placing tray is movably inserted and connected to the inner side of the culture drawer, and an insert rod is fixedly installed at the bottom center of the placing tray.

[0011] A control panel is fixedly installed above the left side wall of the box.

[0012] A heating lamp is fixedly installed transversely on the inner wall of the culture bin above the culture drawer.

[0013] Compared with the prior art, the present invention has the following beneficial effects:

[0014] 1. The present application uses an insulation board, a culture drawer, a slide groove and a slide bar to take out a culture dish from a culture drawer separately without affecting other culture dishes. Since each culture bin is separately provided with a culture drawer, the culture dish in a culture drawer that needs to be taken or placed only needs to be pulled out separately, and the heat in other culture bins will not be lost. Moreover, the pulling and pulling directions of the culture drawers in the two adjacent culture bins are distributed on different side walls of the box body. In this way, multiple culture drawers can be taken and placed at the same time without being blocked by a certain culture drawer, thereby improving the cultivation efficiency and taking and placing efficiency of the device.

[0015] 2. The present application can increase the stability of the culture dish through the fixing holes, the placement tray and the insertion rod. When the culture drawer is pulled out, the culture dish is likely to slide in the culture drawer and may collide with other culture dishes, causing damage. The culture dish is placed on the placement tray and the placement tray is inserted into the fixing hole, so that it remains in place when the culture drawer is pulled out and pushed back, thereby improving the stability of the culture and the insertion position can be freely selected, thereby improving the utilization efficiency of space. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Other features, objects and advantages of the present application will become more apparent by reading the detailed description of non-limiting embodiments with reference to the following drawings:

[0017] Figure 1 This is a schematic diagram of the overall structure of a stem cell cultivation device of the present application;

[0018] Figure 2 This is a schematic diagram of the top cross-sectional structure of a stem cell cultivation device of the present application;

[0019] Figure 3 This is a schematic diagram of the side cross-section structure of a stem cell cultivation device of the present application;

[0020] Figure 4 This is a schematic diagram of the structure of a placement plate of a stem cell cultivation device of the present application.

[0021] In the figure: 1. Box body; 2. Control panel; 3. Slide groove; 4. Slide bar; 5. Culture drawer; 6. Fixing hole; 7. Handle; 8. Heating lamp; 9. Ventilation chamber; 10. Filter; 11. Exhaust fan; 12. Battery; 13. Ventilation duct; 14. Insulation board; 141. Culture chamber; 15. Placement tray; 16. Insert rod. DETAILED DESCRIPTION

[0022] In order to make the technical means, creative features, objectives and effects of the utility model easier to understand, they are further explained below in conjunction with specific implementation methods.

[0023] like Figure 1 As shown, a stem cell cultivation device includes a box body 1, a slide 3, a cultivation drawer 5, an insertion rod 16 and a heat insulation board 14. A control panel 2 is fixedly installed above the left side wall of the box body 1, and the control panel 2 is used to control the heating of the device.

[0024] like Figure 2 A plurality of fixing holes 6 are evenly arranged on the inner bottom of the culture drawer 5 shown in the figure, a filter screen 10 is detachably installed at the opening of the ventilation chamber 9, an exhaust fan 11 is fixedly installed on the side wall of the box body 1 outside the filter screen 10, and a battery 12 is movably placed on the inner side of the ventilation chamber 9. The filter screen 10 can isolate dust, and the battery 12 supplies power to the control panel 2 and the heating lamp 8.

[0025] like Figure 2 and Figure 4 As shown, a placement tray 15 is movably inserted and connected to the inner side of the culture drawer 5, and an insertion rod 16 is fixedly installed at the bottom center of the placement tray 15. A heating lamp tube 8 is laterally fixedly installed on the inner wall of the culture bin 141 above the culture drawer 5, and the insertion rod 16 can be just inserted into the fixing hole 6 to avoid shaking.

[0026] like Figure 2 and Figure 3 The inner side of the box body 1 shown is fixedly installed with four insulation boards 14 in a vertical array, a culture bin 141 is provided at the inner top end of the box body 1 and between two adjacent insulation boards 14, and a slide groove 3 is provided on the inner wall of the culture bin 141, and the slide grooves 3 of two adjacent culture bins 141 are perpendicular to each other, the left and right side walls of the culture drawer 5 are fixedly installed with slide bars 4, and a handle 7 is fixedly installed in the center of the outer wall of the culture drawer 5, the slide bar 4 is horizontally slidably connected on the inner side of the slide groove 3, and the insulation board 14 can isolate the heat, so that the temperature of each layer of the culture bin 141 can be set separately.

[0027] like Figure 3 As shown, a ventilation chamber 9 is provided at the inner bottom of the box body 1 , a ventilation pipe 13 is connected to the side wall of the culture bin 141 , and the other end of the ventilation pipe 13 is connected to the ventilation chamber 9 .

[0028] In actual use, the culture dish of the stem cell is put in by pulling out the culture drawer 5, and then pushing the culture drawer 5 back. After the battery 12 supplies power to the device, the control panel 2 controls the heating lamps 8 in each culture chamber 141 to heat the culture dish. Through the heat insulation board 14, the culture drawer 5, the slide 3 and the slide bar 4, the culture dish in a culture drawer 5 can be taken out separately without affecting other culture dishes. Since each culture chamber 141 is separately provided with a culture drawer 5, the culture dish in which the culture drawer 5 needs to be taken out only needs to be pulled out separately, and the heat in other culture chambers 141 will not be lost. In addition, the pulling and drawing directions of the culture drawers 5 in the two adjacent culture chambers 141 are distributed on different side walls of the box body 1, so that multiple culture drawers can be operated at the same time. 5 for taking and placing, and will not be blocked by a certain culture drawer 5, thereby improving the cultivation efficiency and taking and placing efficiency of the device. At the same time, the stability of the culture dish can be increased by the fixing hole 6, the placement plate 15 and the insertion rod 16. When the culture drawer 5 is pulled out, the culture dish is likely to slide in the culture drawer 5, and may collide with other culture dishes, thereby causing damage. The culture dish is placed in the placement plate 15, and the placement plate 15 is inserted into the fixing hole 6, so that it remains in place when the culture drawer 5 is pulled out and pushed back, thereby improving the stability of cultivation, and the insertion position can be freely selected, thereby improving the utilization efficiency of space. Each culture bin 141 is provided with a ventilation pipe 13 for heat dissipation. After the exhaust fan 11 is started, air can be exhausted to the outside of the box body 1, thereby taking out the heat in the culture bin 141.

Claims

1. A stem cell cultivation device, comprising a housing (1), a slide (3), a cultivation drawer (5), an insertion rod (16) and a heat insulation board (14), characterized in that: Four heat insulation boards (14) are fixedly installed in a vertical array on the inner side of the box (1); a culture chamber (141) is provided at the inner top end of the box (1) and between two adjacent heat insulation boards (14); a slide groove (3) is provided on the inner wall of the culture chamber (141); the slide grooves (3) of the two adjacent culture chambers (141) are perpendicular to each other; a slide bar (4) is fixedly installed on the left and right side walls of the culture drawer (5); a handle (7) is fixedly installed in the center of the outer wall of the culture drawer (5); the slide bar (4) is slidably connected to the inner side of the slide groove (3); a plurality of fixing holes (6) are evenly provided on the inner bottom of the culture drawer (5); a ventilation chamber (9) is provided on the inner bottom of the box (1); a ventilation pipe (13) is connected to the side wall of the culture chamber (141); the other end of the ventilation pipe (13) is connected to the ventilation chamber (9).

2. A stem cell cultivation device according to claim 1, characterized in that: A filter screen (10) is detachably mounted at the opening of the ventilation chamber (9), an exhaust fan (11) is fixedly mounted on the side wall of the box body (1) outside the filter screen (10), and a battery (12) is movably placed inside the ventilation chamber (9).

3. A stem cell cultivation device according to claim 1, characterized in that: A placement tray (15) is movably inserted and connected to the inner side of the culture drawer (5), and an insertion rod (16) is fixedly installed at the center of the bottom of the placement tray (15).

4. A stem cell cultivation device according to claim 1, characterized in that: A control panel (2) is fixedly mounted above the left side wall of the box body (1).

5. The stem cell cultivation device according to claim 1, characterized in that: A heating lamp tube (8) is fixedly installed transversely on the inner wall of the culture bin (141) above the culture drawer (5).

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