Full-automatic tissue dissociation instrument

By using the limit structure of the funnel-shaped guide and the expandable extension body when the test tube is inserted into the insulating box, combined with the design of the guide rod and the sliding channel, the problem of the bottom of the test tube falling next to the socket is solved, and the accuracy of the test tube is achieved Guide and fix to improve separation efficiency.

CN222499176UActive Publication Date: 2025-02-18LINKGEN BIOTECH SHANGHAI CO LTD

Patent Information

Application Number
CN202421082261.8
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-05-17
Publication Date
2025-02-18
Estimated Expiration
2034-05-17

AI Technical Summary

Technical Problem

In the prior art, the test tube may easily fall next to the socket due to lack of guidance when inserted into the incubator, resulting in inconvenience.

Method used

A fully automatic tissue dissociation meter is designed, adopting a limit structure including a guide, an extension body and a pallet. The guide is formed into a funnel-shaped, and the extension body can be expanded. The pallet has a socket to guide the bottom of the test tube to fall on the top of the pallet. and the pallet is kept linearly slipped through the guide rod and the sliding channel, increasing the shaking frequency of the test tube.

Benefits of technology

It realizes accurate guidance and fixation of test tubes, adapts to the clamping of test tubes of different specifications, improves the shaking frequency of test tubes, and enhances the separation efficiency and effect.

✦ Generated by Eureka AI based on patent content.

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  • Figure CN222499176U_ABST
    Figure CN222499176U_ABST
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Abstract

The utility model relates to the technical field of medical instruments, and discloses a full-automatic tissue dissociation instrument which comprises a main body, the heat preservation box is slidably connected to the top of the main body and used for containing a sample, the heat preservation box forms a box body structure, a limiting structure used for supporting and guiding a test tube is arranged in a cavity of the main body and comprises a guiding body, an extending body and a supporting plate, the guiding body is fixedly connected with the heat preservation box, and the extending body is fixedly connected with the guiding body; the wall face of the extending body forms an expandable petal-shaped structure, the supporting plate is elastically connected with the heat preservation box and located under the guiding body, the guiding body can guide the bottom of the test tube to fall on the top face of the supporting plate, the guiding body is arranged, the funnel-shaped guiding body is used for guiding the test tube to fall on the top face of the supporting plate, and the extending body extends towards the supporting plate. The extension body can more accurately guide the test tube to fall, and meanwhile, the extension body can provide certain supporting force for the test tube to inhibit the test tube from inclining, so that the test tube guiding and fixing effects are achieved.
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Description

Technical Field

[0001] The utility model relates to the technical field of medical instruments, in particular to a full-automatic tissue dissociation instrument. Background Art

[0002] The prior art discloses a constant temperature rotating cell tissue dissociation instrument (CN202311503881.4), comprising an insulation component, a drive component and a control component; the insulation component comprises an insulation box for placing test tube reagents, a heating component and a clamping component; the drive component comprises a servo motor, and the servo motor drives the insulation component to rotate and shake around a rotating axis; the control component comprises a temperature controller for controlling the heating temperature of the heating component and a control mainboard for controlling the rotation of the servo motor.

[0003] In the prior art, the test tube is mainly clamped by two mutually elastically connected clamps to achieve the limit of the test tube. The test tube has a certain travel during the process of being inserted into the incubator. When the test tube passes through the two clamps, the lower part of the test tube lacks guidance, which easily causes the bottom of the test tube to fall beside the insertion hole, which has certain inconveniences.

[0004] To this end, we propose a fully automatic tissue dissociation instrument. Utility Model Content

[0005] The utility model mainly solves the technical problems existing in the above-mentioned prior art and provides a full-automatic tissue dissociation instrument.

[0006] In order to achieve the above-mentioned purpose, the utility model adopts the following technical scheme: a fully automatic tissue dissociation instrument, comprising a main body; an incubator for placing samples slidably connected to the top of the main body, the incubator forming a box structure, a limiting structure for supporting and guiding the test tube is provided in the cavity of the main body, the limiting structure comprises a guide body, an extension body and a support plate, the guide body is fixedly connected to the incubator, the extension body is fixedly connected to the guide body, the wall surface of the extension body forms an expandable petal structure, the support plate is elastically connected to the incubator, the support plate is located directly below the guide body, and the guide body can guide the bottom of the test tube to fall on the top surface of the support plate.

[0007] As a preferred embodiment of the utility model, the guide body forms a funnel-shaped structure, the larger port of the guide body is arranged upward, the extension body is fixedly connected to the smaller port of the guide body, the top of the insulation box is open, a plurality of guide bodies are arranged in the insulation box cavity, a removable top cover is provided at the opening of the insulation box, the top cover is locked with the insulation box by bolts, and a plurality of windows corresponding to the guide bodies are opened on the wall surface of the top cover.

[0008] As a preferred embodiment of the present invention, the extension body forms a tubular structure, a wall surface of the extension body is provided with a plurality of deformation grooves, and the extension body forms an expandable petal-like structure through the deformation grooves.

[0009] As a preferred embodiment of the present invention, the deformation groove is formed on the lower end surface of the extension body and extends toward the top end of the extension body, and the depth of the deformation groove is less than the height of the extension body.

[0010] As a preferred embodiment of the present invention, a plurality of insertion holes are provided on the top surface of the support plate, and the insertion holes are distributed in a one-to-one correspondence with the guide bodies.

[0011] As a preferred embodiment of the utility model, the limiting structure also includes a guide rod, a sliding channel and a connecting block. The guide rod is fixedly connected to the insulation box, the sliding channel is opened on the top of the guide rod, the connecting block is located in the sliding channel, an elastic member is provided in the sliding channel, the connecting block is elastically connected to the guide rod through the elastic member, and the support plate is fixedly installed on the top surface of the connecting block.

[0012] As a preferred embodiment of the utility model, two mutually parallel guide rods are arranged in the cavity of the heat preservation box, at least three support plates are arranged on the top surfaces of the guide rods, and the support plates and the guide rods are distributed in a cross shape.

[0013] As a preferred embodiment of the utility model, the connecting block forms a block structure adapted to the sliding channel, a plurality of partitions are fixedly installed in the sliding channel, a connecting block is arranged between two adjacent partitions, and an elastic member is arranged on both sides of each connecting block, and the elastic member is a spring.

[0014] Beneficial Effects

[0015] The utility model provides a fully automatic tissue dissociation instrument. It has the following beneficial effects:

[0016] 1. This fully automatic tissue dissociation instrument, by setting a guide body, uses the funnel-shaped guide body to guide the test tube to fall to the top surface of the support plate, and sets an extension body, which extends toward the support plate. The extension body can guide the test tube to fall more accurately. At the same time, the extension body can provide a certain supporting force for the test tube, inhibit the test tube from tilting, and has the effect of guiding and fixing the test tube.

[0017] 2. This fully automatic tissue dissociation instrument, by setting a deformation groove, uses the deformation groove to make the extension body form a petal-like structure, so that when the test tube is inserted into the extension body, the extension body can expand, and the extension body can better wrap the test tube. The expandable extension body and the guide body can adapt to the clamping of test tubes of different specifications within a certain range.

[0018] 3. This fully automatic tissue dissociation instrument, by setting a guide rod, uses the connecting block to slide in the sliding channel, so that the support plate maintains linear sliding. During the reciprocating motion of the incubator, the slidable support plate can make the test tube dropped into the socket shake along with the support plate, which can increase the shaking frequency of the test tube and improve the dissociation efficiency and effect. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 This is one of the overall three-dimensional diagrams of the utility model;

[0020] Figure 2 This is the second overall stereogram of the utility model;

[0021] Figure 3 It is a stereoscopic diagram of the guide body and the extension body of the utility model;

[0022] Figure 4 This is a schematic diagram of the installation of the support plate and the thermal insulation box of the utility model;

[0023] Figure 5 This is a schematic diagram of the installation of the guide rod and the heat preservation box of the utility model.

[0024] Legend: 10, main body; 11, insulation box; 20, guide body; 21, extension body; 22, deformation groove; 30, support plate; 31, socket; 32, guide rod; 33, sliding channel; 34, connecting block. DETAILED DESCRIPTION

[0025] A fully automatic tissue dissociation instrument, such as Figure 1 and Figure 2 As shown, it includes a main body 10; a heat preservation box 11 for placing samples is slidably connected to the top of the main body 10, and the heat preservation box 11 forms a box structure. Specifically, an electric cylinder is installed on the top surface of the main body 10, and the heat preservation box 11 is fixedly connected to the output shaft of the electric cylinder. A slide rail is installed on the top surface of the main body 10, and a slideway is provided on the slide rail. A slider is provided in the slideway, and the heat preservation box 11 is fixedly installed on the top surface of the slider. The heat preservation box 11 is pushed back and forth by the push cylinder to promote the mixing of the sample and the reagent to achieve the purpose of dissociation. Of course, the wall of the main body 10 should also be installed with components such as a control switch, a control panel and a plug. This is an existing well-known technology and will not be elaborated here.

[0026] like Figure 2 , Figure 3 and Figure 4As shown, a limiting structure for supporting and guiding the test tube is provided in the cavity of the main body 10, and the limiting structure includes a guide body 20, an extension body 21 and a support plate 30. The guide body 20 is fixedly connected to the incubator 11, and the extension body 21 is fixedly connected to the guide body 20. The wall surface of the extension body 21 forms an expandable petal-like structure. The support plate 30 is elastically connected to the incubator 11. The support plate 30 is located directly below the guide body 20. The guide body 20 can guide the bottom of the test tube to fall on the top surface of the support plate 30. The guide body 20 forms a funnel-shaped structure. The larger port of the guide body 20 is set upward, and the extension body 21 is fixedly connected to the smaller port of the guide body 20. The top of the incubator 11 is open, and the cavity of the incubator 11 is set A plurality of guide bodies 20 are provided at the opening of the insulated box 11, and a detachable top cover is locked with the insulated box 11 by bolts. A plurality of windows corresponding to the guide bodies 20 are provided on the wall surface of the top cover, and a plurality of insertion holes 31 are provided on the top surface of the support plate 30, and the insertion holes 31 are distributed one-to-one with the guide bodies 20. In the present scheme, by setting the guide body 20, the funnel-shaped guide body 20 is utilized to guide the test tube to fall to the top surface of the support plate 30, and an extension body 21 is provided, and the extension body 21 extends toward the support plate 30. The extension body 21 can guide the test tube to fall more accurately, and at the same time, the extension body 21 can provide a certain supporting force for the test tube, suppress the tilt of the test tube, and has the effect of guiding and fixing the test tube.

[0027] like Figure 3 As shown, the extension body 21 forms a tubular structure, and a plurality of deformation grooves 22 are provided on the wall surface of the extension body 21. The extension body 21 forms an expandable petal-like structure through the deformation grooves 22. The deformation grooves 22 are provided on the lower end surface of the extension body 21 and extend toward the top of the extension body 21. The depth of the deformation grooves 22 is less than the height of the extension body 21. In the present embodiment, the deformation grooves 22 are provided and utilized to form a petal-like structure in the extension body 21, so that when the test tube is inserted into the extension body 21, the extension body 21 can be expanded, and the extension body 21 can better wrap the test tube. The expandable extension body 21 and the guide body 20 can adapt to the clamping of test tubes of different specifications within a certain range.

[0028] like Figure 4 and Figure 5As shown, the limiting structure also includes a guide rod 32, a sliding channel 33 and a connecting block 34. The guide rod 32 is fixedly connected to the heat preservation box 11. The sliding channel 33 is provided on the top of the guide rod 32. The connecting block 34 is located in the sliding channel 33. An elastic member is provided in the sliding channel 33. The connecting block 34 is elastically connected to the guide rod 32 through the elastic member. The support plate 30 is fixedly installed on the top surface of the connecting block 34. Two mutually parallel guide rods 32 are provided in the cavity of the heat preservation box 11. At least three support plates 30 are provided on the top surface of the guide rod 32. The support plates 30 and the guide rods 32 are cross-distributed. The connecting block 34 forms an appropriate A block structure is provided with a sliding channel 33, in which a plurality of partitions are fixedly installed, a connecting block 34 is arranged between two adjacent partitions, and an elastic member is arranged on both sides of each connecting block 34, and the elastic member is a spring. As a supplementary explanation to the above scheme, a guide rod 32 is arranged, and the connecting block 34 is utilized to slide in the sliding channel 33, so that the support plate 30 maintains linear sliding. During the reciprocating motion of the incubator 11, the slidable support plate 30 can make the test tube falling into the socket 31 shake along with the support plate 30, thereby increasing the shaking frequency of the test tube and improving the dissociation efficiency and effect.

[0029] The working principle of the utility model is as follows: a test tube containing a sample is inserted into the window of the top cover, and a funnel-shaped guide body 20 is used to guide the test tube to fall to the top surface of the support plate 30, and an extension body 21 is provided, which extends toward the support plate 30. The extension body 21 can more accurately guide the test tube to fall into the insertion hole on the top surface of the support plate 30, and the deformation groove 22 is used to form a petal-like structure in the extension body 21, so that the extension body 21 can expand when the test tube is inserted into the extension body 21, so that the extension body 21 can better wrap the test tube, and can also adapt to test tubes of different specifications within a certain range, and the connecting block 34 is used to slide in the sliding channel 33, so that the support plate 30 maintains linear sliding, and during the reciprocating motion of the incubator 11, the slidable support plate 30 can make the test tube dropped in the insertion hole 31 shake with the support plate 30, thereby increasing the reciprocating shaking frequency of the test tube and improving the dissociation efficiency.

[0030] The above shows and describes the basic principle and main features of the utility model and the advantages of the utility model. Those skilled in the art should understand that the utility model is not limited by the above embodiments. The above embodiments and descriptions are only for explaining the principle of the utility model. Without departing from the spirit and scope of the utility model, the utility model may have various changes and improvements, which fall within the scope of the utility model to be protected. The scope of protection claimed by the utility model is defined by the attached claims and their equivalents.

Claims

1. A fully automatic tissue dissociation instrument, comprising a main body (10); a heat preservation box (11) for placing a sample and slidably connected to the top of the main body (10), the heat preservation box (11) forming a box structure, characterized in that: A limiting structure for supporting and guiding the test tube is provided in the cavity of the main body (10), the limiting structure comprising a guide body (20), an extension body (21) and a support plate (30), the guide body (20) being fixedly connected to the heat preservation box (11), the extension body (21) being fixedly connected to the guide body (20), the wall surface of the extension body (21) forming an expandable petal-shaped structure, the support plate (30) being elastically connected to the heat preservation box (11), the support plate (30) being located directly below the guide body (20), and the guide body (20) being able to guide the bottom of the test tube to fall on the top surface of the support plate (30).

2. The fully automatic tissue dissociation instrument according to claim 1, characterized in that: The guide body (20) forms a funnel-shaped structure, the larger end of the guide body (20) is arranged upward, the extension body (21) is fixedly connected to the smaller end of the guide body (20), the top of the heat preservation box (11) is open, a plurality of guide bodies (20) are arranged in the cavity of the heat preservation box (11), a detachable top cover is arranged at the opening of the heat preservation box (11), the top cover is locked with the heat preservation box (11) by bolts, and a wall surface of the top cover is provided with a plurality of windows corresponding to the guide bodies (20) one by one.

3. The fully automatic tissue dissociation instrument according to claim 1, characterized in that: The extension body (21) forms a tubular structure, and a plurality of deformation grooves (22) are provided on the wall surface of the extension body (21). The extension body (21) forms an expandable petal-shaped structure through the deformation grooves (22).

4. The fully automatic tissue dissociation instrument according to claim 3, characterized in that: The deformation groove (22) is formed on the lower end surface of the extension body (21) and extends toward the top end of the extension body (21); the depth of the deformation groove (22) is less than the height of the extension body (21).

5. The fully automatic tissue dissociation instrument according to claim 1, characterized in that: A plurality of insertion holes (31) are provided on the top surface of the support plate (30), and the insertion holes (31) are distributed in a one-to-one correspondence with the guide bodies (20).

6. The fully automatic tissue dissociation instrument according to claim 1, characterized in that: The limiting structure also includes a guide rod (32), a sliding channel (33) and a connecting block (34); the guide rod (32) is fixedly connected to the heat preservation box (11); the sliding channel (33) is provided on the top of the guide rod (32); the connecting block (34) is located in the sliding channel (33); an elastic member is provided in the sliding channel (33); the connecting block (34) is elastically connected to the guide rod (32) via the elastic member; and the support plate (30) is fixedly mounted on the top surface of the connecting block (34).

7. The fully automatic tissue dissociation instrument according to claim 6, characterized in that: Two mutually parallel guide rods (32) are arranged in the cavity of the heat preservation box (11), at least three support plates (30) are arranged on the top surface of the guide rods (32), and the support plates (30) and the guide rods (32) are distributed in a cross shape.

8. The fully automatic tissue dissociation instrument according to claim 6, characterized in that: The connecting block (34) forms a block structure adapted to the sliding channel (33); a plurality of partitions are fixedly installed in the sliding channel (33); a connecting block (34) is arranged between two adjacent partitions; and an elastic member is arranged on both sides of each connecting block (34); the elastic member is a spring.

Citation Information

Patent Citations

  • Constant-temperature rotary cell tissue dissociation instrument

    CN117327564A

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