Luer multi-channel connector with forced mixing assisting function and mixing suite

Abstract

The utility model provides a Luer multi-channel connector with a forced mixing assisting function and a mixing suite. The Luer multi-channel connector with the forced mixing assisting function comprises a forced mixing assembly, and at least two Luer connectors are arranged outside the forced mixing assembly for connection; the forced mixing assembly comprises an I-shaped hollow cavity, a Y-shaped hollow cavity, an L-shaped hollow cavity, a V-shaped hollow cavity or an X-shaped hollow cavity and a built-in mixing assisting part, and the mixing suite comprises a Luer multi-channel connector with a forced mixing assisting function, at least one injector pre-filled with liquid and at least one injector pre-filled with solid-phase powder which are combined to form a closed forced mixing system. By alternately pushing the plunger rods of the at least two injectors, liquid and solid powder or another liquid are alternately forced in a reciprocating manner in the plurality of injectors through the mixing suite for multiple times to obtain homogeneous solid-liquid or liquid-liquid mixture. According to the utility model, the solid phase and the liquid phase which are pre-filled in the injector can be conveniently and quickly forced to be mixed, bubbles can be reduced, external pollution and material waste are avoided, and the operation preparation time is shortened.

Description

Technical Field

[0001] The utility model belongs to the field of medical devices, and particularly relates to the technical field of a Luer multi-channel connector with a forced-mixing-assisted function and its combined application with a prefilled syringe, and specifically relates to a Luer multi-channel connector with a forced-mixing-assisted function and a mixing kit. Background Art

[0002] Injectable filling materials are surgical implants that are injected or filled locally through minimally invasive methods. During surgery, the independently packaged solid and liquid phases usually need to be evenly mixed and formulated into a slurry or mixed liquid of a certain viscosity before being loaded into a syringe for in vivo injection and filling, so uniform mixing is essential. However, in clinical applications, manual stirring and mixing in an open container is often used. The operation process is not only laborious, but also involves the risk of contamination and material waste during the stirring and mixing in an open container and the subsequent transfer and filling of the syringe. The cumbersome operation also prolongs the surgical preparation time. Traditional manual mixing cannot be fast, fully and evenly mixed, and it is very easy to introduce air during the slurry stirring process. At the same time, the traditional mixing process is time-consuming and is not suitable for products where solid and liquid phases are easily reacted, and cannot meet clinical application requirements. On the other hand, the solid and liquid phases of commercially available injectable filling materials are usually packaged in separate sterile bags or bottles. When in use, the process of unpacking the bags and opening the bottles will also increase the risk of contamination and will more or less cause material loss. It is difficult to ensure that the solid and liquid phases are mixed strictly in proportion in actual operation. Material filling loss or deviation of the solid-liquid ratio from the optimal formula will change the various properties of the injectable filling materials and affect the clinical application effect of the injectable filling materials.

[0003] In view of the above problems, CN100450453C discloses an integrated bone cement vacuum stirring syringe, including a stirring device, a vacuum chamber and a syringe, wherein the stirring device is composed of a transmission shaft and stirring blades. However, when using this integrated bone cement vacuum stirring syringe, it is not only necessary to load the solid and liquid phases that have been packaged according to the proportion into the vacuum stirring syringe shell on site, install the vacuum agitator, pull the transmission shaft into place, connect the vacuum chamber with the syringe shell, shake the stirring device handle to stir the bone cement evenly, then remove the vacuum agitator, and then connect it to the bone cement gun for in vivo injection and other procedures. The stirring device is complicated and the operation process is very cumbersome. In addition, the agitator is provided with many stirring blades, which are repeatedly used, which easily pollutes the bone cement and causes a large amount of material waste. At the same time, manual stirring is inefficient and difficult to mix evenly.

[0004] It should be noted that the above contents belong to the technical cognition scope of the inventor. Since the technical contents in this field are vast and too complicated, the above contents of this application do not necessarily constitute prior art. Utility Model Content

[0005] 1. Technical problems to be solved by the utility model:

[0006] The utility model provides a Luer multi-channel connector and a mixing kit with a forced mixing aid function, which are used to solve the technical problems existing in the above-mentioned background technology.

[0007] 2. Technical solution:

[0008] In order to achieve the above-mentioned purpose, the technical solution provided by the utility model is: comprising a forced mixing component and at least two Luer connectors; the forced mixing component and the Luer connector are integrated into one body, and there is a channel inside the forced mixing component that passes through and connects from any one of the Luer connectors to any other one of the Luer connectors.

[0009] Furthermore, the forced mixing component includes an I-type, Y-type, L-type, V-type or X-type hollow cavity, and a built-in mixing aid is provided in the hollow cavity; the Luer connector is a male Luer connector or a female Luer connector or a combination thereof; at least two Luer connectors are provided outside the forced mixing component and connected thereto; the central channel of the Luer connector is connected through the hollow cavity of the forced mixing component to form a channel through which a multi-component liquid or slurry is forced to flow through the built-in mixing aid and be fully mixed.

[0010] Furthermore, the Luer connector is three-dimensionally distributed around the forced mixing component, and the Luer connector and the forced mixing component are connected and integrated into one by platform gluing, heat sealing or threaded interface, and the central axes of the Luer connectors around the forced mixing component are distributed at a three-dimensional angle greater than 0° and less than or equal to 180°.

[0011] Furthermore, the built-in mixing aid is at least one relatively fixed porous plate disposed in the hollow cavity;

[0012] The porous plate is evenly distributed with at least one circular, rectangular, polygonal, crescent-shaped or plum-shaped channel hole penetrating the porous plate;

[0013] The porous plates are arranged at intervals in the hollow cavity and intersect with the symmetric central axis of the channel in the hollow cavity. Gaps are left between the porous plates, and the symmetric centers of the channel holes on adjacent porous plates are arranged in a staggered manner.

[0014] Furthermore, the built-in mixing aid is at least one relatively fixed screw or at least one screw that can be forced to rotate around its central axis arranged in the hollow cavity, and the central axis of the screw is embedded in the connection between the Luer connector and the hollow cavity.

[0015] Furthermore, the inner surface of the hollow cavity is a circular cylinder or a polygonal cylinder, forming a smooth inner surface channel; the outer surface of the hollow cavity is a circular cylinder, a polygonal cylinder or a plum blossom-shaped cylinder, which envelops the outer contour of an I-type, Y-type, L-type, V-type or X-type hollow cavity.

[0016] Furthermore, the Luer connector or the forced mixing component is prepared by any one or more of medical-grade cycloolefin copolymer, polyethylene PE, polyvinyl chloride PVC, polymethyl methacrylate PMMA, polystyrene PS, polycarbonate PC, polypropylene PP, thermoplastic polyurethane TPU, polytetrafluoroethylene PTFE, polyamide PA, polyetheretherketone PEEK, polyaryletherketone PAEK, polyetherketoneketone PEKK, styrene acrylonitrile copolymer SAN, and styrene-methyl methacrylate copolymer MS.

[0017] Furthermore, the Luer connector or the forced mixing assembly is respectively prepared by injection molding and then assembled into one by gluing, heat sealing or threading.

[0018] Furthermore, the Luer connector or the forced mixing component is integrally manufactured in one go using additive manufacturing technology.

[0019] Also protected is a mixing kit of a Ruhr multi-channel connector with a forced mixing aid function, which includes the Ruhr multi-channel connector with the forced mixing aid function, wherein the Ruhr multi-channel connector with the forced mixing aid function is connected to at least two pre-filled solid phase or pre-filled liquid phase syringes, and the central axes of the pre-filled solid phase or pre-filled liquid phase syringes are distributed around the Ruhr multi-channel connector with the forced mixing aid function at a solid angle greater than 0° and less than or equal to 180°.

[0020] 3. Beneficial effects:

[0021] Compared with the prior art, the technical solution provided by the utility model has the following beneficial effects:

[0022] The utility model has reasonable design and provides a Luer multi-channel connector with a forced mixing function, which is simple in structure, low in production cost and easy to mass produce;

[0023] By arranging a forced mixing component between the Luer connectors, the solid and liquid phases pre-filled in two syringes can be conveniently, quickly and uniformly forced to mix, thereby reducing bubbles, avoiding external contamination and material waste;

[0024] At the same time, adding built-in mixing aids between the forced mixing components can force the solid and liquid phase mixtures to pass through various forms of channels in the hollow cavity, extend the channel length of the forced stirring and mixing of the solid and liquid phases, and greatly improve the mixing efficiency of the solid and liquid phases, so as to achieve the purpose of ready-to-use after mixing. It is particularly suitable for product applications in which the components of solid and liquid phase materials are prone to react when mixing and the curing reaction time is very short. It is also suitable for the mixing of materials with poor compatibility of the physical and chemical properties of the solid and liquid phases.

[0025] The invention is beneficial to shorten the operation preparation time and is very convenient to use. It is particularly suitable for achieving uniform mixing of solid-phase mixed materials with different densities and liquid-phase by rapid forced stirring motion.

[0026] The present application fills the solid phase powder into the syringe barrel prefilled with solid phase powder, and fills the liquid phase into the syringe barrel prefilled with liquid phase, and together with the Luer multi-channel connector with forced mixing function, forms a kit, which is then sterilized and marketed. The solid-liquid mixing kit has a reasonable configuration, simple composition, and low cost. When used clinically, just unplug the Luer plug, and connect the two ends of the Luer multi-channel connector with forced mixing function to the male Luer connectors of the syringes prefilled with liquid phase and prefilled with solid phase powder, respectively, to form an internally closed solid-liquid forced mixing system. The operation is very simple, which can not only avoid bacterial contamination caused by material exposure, avoid bubble formation, material loss, and improve material utilization, but also because the double female Luer multi-channel connector with forced mixing function and the prefilled syringe are disposable, there is no cross contamination.

[0027] By pushing the plungers of two prefilled syringes in sequence, the solid-liquid mixture is passed through the Luer multi-channel connector with forced mixing function for multiple times. The solid-liquid mixture is subjected to forced extrusion and shear force through the built-in mixing aid, so that materials of different densities are quickly forced to stir and evenly mix. On the basis of eliminating the disadvantages of traditional propeller stirring methods such as exogenous pollution and slurry loss, the mixing efficiency and quality are greatly improved, and a uniform mixture can be obtained in a short time. It can not only meet the clinical application requirements of homogenizing and defoaming injectable filling materials with rapid solidification, high viscosity, large difference in component specific gravity and poor compatibility of physical and chemical properties, and avoiding air mixing, but also can greatly save mixing and injection waiting time, simplify surgical preparation procedures, and reduce the risk of operational errors.

[0028] It should be noted that the structures not introduced in the present invention are not related to the design points and improvement directions of the present invention, and are the same as the prior art or can be implemented by using the prior art, and will not be described in detail here. BRIEF DESCRIPTION OF THE DRAWINGS

[0029] Figure 1 This is one of the schematic diagrams of the structure of the L-shaped double female Luer connector with forced mixing function made by the additive process of the utility model;

[0030] Figure 2 This is one of the schematic cross-sectional views of the structure of a type I double female Luer connector with forced mixing function manufactured by the additive process of the utility model;

[0031] Figure 3 This is the second schematic diagram of the cross-sectional view of the structure of the L-shaped double female Luer connector with forced mixing function made by the additive process of the utility model;

[0032] Figure 4 This is the third schematic diagram of the cross-sectional view of the structure of the L-shaped double female Luer connector with forced mixing function made by the additive process of the utility model;

[0033] Figure 5 One of the schematic diagrams of the utility model Luer connector, which is assembled by threads and has an I-type double female Luer connector with forced mixing function, with a threaded rod in the middle;

[0034] Figure 6 It is a schematic diagram of the threaded rod in the middle of the Ruhr multi-channel joint structure with forced mixing function of the utility model.

[0035] Figure 7 This is one of the schematic diagrams of the structure of the I-type double female Luer connector with forced mixing function made by the injection molding process of the utility model;

[0036] Figure 8 This is one of the schematic cross-sectional views of the structure of the I-type double female Luer connector with forced mixing function manufactured by the injection molding process of the utility model;

[0037] Fig. 9 This is the second schematic diagram of the cross-sectional view of the structure of the I-type double female Luer connector with forced mixing function made by the injection molding process of the utility model;

[0038] Fig.10 This is the third schematic diagram of the cross-sectional view of the structure of the I-type double female Luer connector with forced mixing function made by the injection molding process of the utility model;

[0039] Fig.11 It is a schematic diagram of the structure of the Y-shaped Ruhr multi-channel joint with forced-mixing function of the utility model;

[0040] Fig.12 It is a schematic diagram of the structure of the X-shaped Ruhr multi-channel joint with forced mixing function of the utility model;

[0041] Fig.13 The utility model is a schematic diagram of the structure of a double female Luer connector which is assembled by heat sealing or gluing.

[0042] Reference numerals:

[0043] 1. Forced mixing component; 2. Luer connector; 3. Hollow cavity; 4. Built-in mixing aid; 5. Perforated plate; 6. Screw. DETAILED DESCRIPTION

[0044] To facilitate the understanding of the present invention, the present invention will be described more comprehensively below with reference to the relevant drawings. Several embodiments of the present invention are given in the drawings. However, the present invention can be implemented in many different forms and is not limited to the embodiments described herein. On the contrary, the purpose of providing these embodiments is to make the disclosure of the present invention more thorough and comprehensive.

[0045] In the description of the present invention, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "page", "bottom", "inside", "outside", "clockwise", "counterclockwise", etc., indicating the orientation or position relationship, are based on the orientation or position relationship shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present invention.

[0046] In addition, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" and "second" may explicitly or implicitly include one or more of the features. In the description of the present utility model, the meaning of "plurality" is two or more, unless otherwise clearly and specifically defined.

[0047] In the present invention, unless otherwise clearly specified and limited, the terms "installed", "connected", "connected", "fixed", "provided with", "provided on" and the like should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be an indirect connection through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances. Example

[0048] See attached Figure 1-13A Luer multi-channel connector with a forced mixing function comprises a forced mixing component 1 and at least two Luer connectors 2; the forced mixing component 1 is integrated with the Luer connectors 2, and there is a channel inside the forced mixing component 1 that runs through and connects any one of the Luer connectors 2 to any other Luer connectors 2. When the device is working, the Luer connectors 2 can be connected to the Luer interfaces of syringes respectively, and the syringes are pre-filled with solids or liquids to be mixed. The syringes at both ends move back and forth respectively, and the solids or liquids inside repeatedly pass through the space in the middle of the forced mixing component 1, thereby achieving a forced mixing effect of the solid and liquid phases.

[0049] The Luer connector 2 is three-dimensionally distributed around the forced mixing component 1. The Luer connector 2 and the forced mixing component 1 are connected and integrated into one by platform gluing, heat sealing or threaded interface. The central axes of the Luer connectors 2 around the forced mixing component 1 are distributed at a three-dimensional angle greater than 0° and less than or equal to 180°. The forced mixing component 1 can be connected to multiple Luer connectors 2 and connected to a syringe to achieve a mixing effect of multiple solids and liquids.

[0050] The forced mixing component 1 includes an I-type, Y-type, L-type, V-type or X-type hollow cavity 3, and a built-in mixing aid 4 is arranged in the hollow cavity 3; the Luer connector 2 is a male Luer connector or a female Luer connector or a combination thereof; at least two Luer connectors 2 are arranged outside the forced mixing component 1 to be connected thereto; the central channel of each Luer connector 2 is connected through the hollow cavity 3 of the forced mixing component 1 to form a channel through which a multi-component liquid or slurry is forced to flow through the built-in mixing aid 4 and be fully mixed. The limitation of the hollow cavity 3 here is only a conventional shape, and it can also be other irregular shapes. The structure of the hollow cavity 3 is convenient for connecting multiple Luer connectors 2 to syringes, and the built-in mixing aid 4 facilitates the forced circulation and mixing of the substances circulating inside.

[0051] The built-in mixing aid 4 is at least one relatively fixed porous plate 5 disposed in the hollow cavity 3;

[0052] The porous plate 5 is evenly distributed with at least one circular, rectangular, polygonal, crescent-shaped or plum-shaped channel hole penetrating the porous plate 5;

[0053] The porous plates 5 are arranged at intervals in the hollow cavity 3 and intersect with the symmetric center axis of the channel in the hollow cavity 3. Gaps are left between the porous plates 5, and the symmetric centers of the channel holes on adjacent porous plates 5 are arranged in a staggered manner.

[0054] The arrangement of the porous plate 5 is conducive to the rapid circulation and mixing of the internal substances.

[0055] The built-in mixing aid 4 is at least one relatively fixed screw 6 or at least one screw 6 that can be forced to rotate around its central axis, which is arranged in the hollow cavity 3. The central axis of the screw 6 is embedded in the connection between the Luer connector 2 and the hollow cavity 3. The forced rotating screw 6 facilitates the rapid forced mixing of the materials flowing back and forth. The diameter of the screw 6 is smaller than the diameter of the channel in the hollow cavity 3. During installation, the screw can be directly placed in the hollow cavity, and then the Luer connector 2 is installed at the port of the hollow cavity 3.

[0056] The inner surface of the hollow cavity 3 is a circular cylinder or a polygonal cylinder, forming a smooth inner surface channel to facilitate the flow of internal substances;

[0057] The outer surface of the hollow cavity 3 is a circular cylinder, a polygonal cylinder or a plum blossom-shaped cylinder, which envelops the outer contour of the hollow cavity 3 into an I-type, Y-type, L-type, V-type or X-type, thereby improving the overall structural strength.

[0058] The Luer connector 2 or the forced mixing component 1 is made of any one or more of medical-grade cycloolefin copolymer, polyethylene PE, polyvinyl chloride PVC, polymethyl methacrylate PMMA, polystyrene PS, polycarbonate PC, polypropylene PP, thermoplastic polyurethane TPU, polytetrafluoroethylene PTFE, polyamide PA, polyetheretherketone PEEK, polyaryletherketone PAEK, polyetherketoneketone PEKK, styrene acrylonitrile copolymer SAN, and styrene-methyl methacrylate copolymer MS. It should be noted that the device can be made of non-medical materials in usage scenarios.

[0059] The Luer connector 2 or the forced mixing assembly 1 is respectively prepared by injection molding process and then assembled into one by gluing, heat sealing or threading.

[0060] The Luer connector 2 and the forced mixing assembly 1 are integrally formed in one step by using additive manufacturing technology.

[0061] And a mixing kit of a Luer multi-channel connector with a forced mixing-aid function, comprising the Luer multi-channel connector with the forced mixing-aid function, wherein the Luer multi-channel connector with the forced mixing-aid function is connected to at least two pre-filled solid phase or pre-filled liquid phase syringes, and the central axes of the pre-filled solid phase or pre-filled liquid phase syringes are distributed around the Luer multi-channel connector with the forced mixing-aid function at a solid angle greater than 0° and less than or equal to 180°.

[0062] It should be noted that the syringe can be a common syringe in the current technology, and its main purpose is to provide the driving force required for the flow of the solid phase and the liquid phase in the syringe, so that the internal substances move back and forth in a vacuum environment to achieve a forced mixing effect. The following is an example of a common syringe. For example, the solid-liquid mixing kit includes a forced mixing component 1 with two Luer connectors 2, a pre-filled liquid phase syringe and a pre-filled solid phase powder syringe; the two Luer connectors 2 are respectively connected to the Luer connectors of the above two syringes, so that the three are connected in series to form a closed mixing system; the pre-filled liquid phase syringe or the pre-filled solid phase powder syringe are respectively composed of a barrel The invention is composed of a body, a plunger rod, a female Luer plug and liquid or solid phase powder; one end of the body is open and has two fin-shaped shoulders, and the other end is provided with a male Luer connector and sealed by a female Luer plug; one end of the plunger rod is provided with a push handle and the other end is provided with a piston, and can freely slide back and forth in the body of the body; the plunger rod of the syringe pre-filled with liquid phase is pushed to inject the liquid phase into the syringe pre-filled with solid phase powder through the Luer connector 2 with forced mixing function, and then the plunger rod of the syringe pre-filled with solid phase powder is pushed to inject the liquid-solid mixture in the syringe into the syringe pre-filled with liquid phase through the Luer connector 2 with forced mixing function, and this is repeated for multiple times to obtain a uniform mixture.

[0063] The following is an example of a pre-filled liquid phase syringe in combination with actual conditions. The pre-filled syringe includes a pre-filled liquid phase syringe and a pre-filled solid phase powder syringe. The barrel of the pre-filled liquid phase syringe is pre-filled with a certain dose of liquid phase, and the liquid phase can be medical grade methyl methacrylate MMA monomer or sterile water, water for injection, disodium hydrogen phosphate solution, sodium dihydrogen phosphate solution, citric acid solution, hyaluronic acid, carboxymethyl cellulose solution, sodium carboxymethyl cellulose solution, N-methyl pyrrolidone solution, polyethylene glycol or Blood, at least one mixture; a certain dose of solid phase powder is pre-filled in the barrel of the syringe pre-filled with solid phase powder, and the solid phase powder can be a polymer composed of medical grade polymethyl methacrylate homopolymer or a copolymer containing polymethyl methacrylate or a mixture of the two, or α-tricalcium phosphate, tetracalcium phosphate, calcium sulfate hemihydrate, dicalcium silicate, tricalcium silicate, strontium silicate, distrontium silicate, tristrontium silicate, hydroxyapatite, hydroxyapatite / β-tricalcium phosphate dual-phase powder or microspheres, at least one mixture.

[0064] The following is an application example 1 of the present application in combination with specific circumstances. Figure 5 , Figure 6Medical grade polypropylene is used for injection molding to form a hollow cavity 3 and a forced rotating screw 6, and the forced rotating screw 6 of polypropylene is installed in the hollow cavity 3 to form a polypropylene forced mixing component 1; when the solid and liquid phase mixture is forced to pass through the polypropylene screw 6 type forced mixing component 1, the solid and liquid phase mixture will be forced to flow along the surface of the screw 6, realizing the forced mixing function of the solid and liquid phases; when the solid and liquid phases are forced to flow, the polypropylene screw 6 can be forced to rotate relative to the central axis of the polypropylene hollow tube in the polypropylene hollow cavity 3; the inner surface of the polypropylene hollow cavity 3 is a circular cylinder, which is a smooth surface channel; the outer surface of the polypropylene hollow cavity 3 is a circular cylinder; platforms are provided at both ends of the polypropylene hollow cavity 3, and are respectively glued and fixed to the polypropylene Luer connector 2, and the three are sequentially combined into a type I polypropylene double female Luer connector with forced mixing function.

[0065] Medical grade polymethyl methacrylate homopolymer powder is filled into a syringe barrel pre-filled with solid phase powder, and methyl methacrylate MMA monomer is filled into a syringe barrel pre-filled with liquid phase, and the kit is packaged together with a polypropylene Luerdo connector with a forced mixing function and then sterilized.

[0066] During clinical use, the solid-liquid mixing kit package is opened, and the Luer plugs on the two syringes prefilled with polymethyl methacrylate homopolymer powder and prefilled with methyl methacrylate MMA monomer are respectively unplugged, and the polypropylene Luer multi-channel connector with forced mixing function is connected to the Luer connectors of the syringes prefilled with methyl methacrylate MMA monomer and prefilled polymethyl methacrylate homopolymer powder respectively; then, the plungers of the two syringes are pushed in turn to make the solid and liquid phase mixtures repeatedly pass through the hollow cavity 3 of the polypropylene Luer multi-channel connector with forced mixing function. When passing through the polypropylene hollow cavity 3, the built-in polypropylene screw 6 is forced to rotate relative to the central axis of the hollow cavity 3, so that the solid and liquid phase mixtures of the polymethyl methacrylate homopolymer powder and the methyl methacrylate MMA monomer are subjected to forced stirring, extrusion and shear force, so that the materials of different densities are self-stirred to achieve uniform mixing, completely avoiding external pollution and material waste, and a bubble-free uniform mixture can be obtained within 1 minute, which can be mixed and used immediately, greatly shortening the surgical preparation time.

[0067] The following is an application example 2 of the present application in combination with specific circumstances. Fig. 9First, medical-grade polycarbonate is used to separately prepare a Luer connector 2, a hollow cavity 3, and a porous plate 5 with 6 through holes of 1 mm in diameter uniformly distributed by injection molding, and the three porous plates 5 are fixedly installed in the hollow cavity 3 with a parallel spacing of 2 mm, and the through holes on the porous plates 5 are staggered; the polycarbonate porous plates 5 are arranged inside the polycarbonate hollow cavity 3 to form a polycarbonate forced mixing component 1, and when the mixture is forced to pass through the polycarbonate forced mixing component 1, the solid and liquid phases are forced to mix; the polycarbonate porous plates 5 are fixed in the polycarbonate hollow cavity 3; the inner cylindrical surface of the polycarbonate hollow cavity 3 is a hexagonal cylindrical surface, which is a smooth surface channel; the outer cylindrical surface of the polycarbonate hollow cavity 3 is a hexagonal cylindrical surface; both ends of the polycarbonate hollow cavity 3 are provided with internal threads, and are respectively connected with one end of the polycarbonate Luer connector 2 with external threads, and the three are sequentially combined into an integrated polycarbonate Luer multi-pass connector with a forced mixing function.

[0068] Medical-grade hydroxyapatite microsphere powder is filled into a syringe barrel pre-filled with solid phase powder, and cross-linked hyaluronic acid is filled into a syringe barrel pre-filled with liquid phase. Together with a polycarbonate Luer multi-channel connector with forced mixing function, the kit is packaged and sterilized.

[0069] During clinical use, the solid-liquid mixing kit package is opened, and the Luer plugs on the two syringes prefilled with hydroxyapatite microsphere powder and prefilled with cross-linked hyaluronic acid are respectively unplugged, and the two ends of the polycarbonate Luer multi-way connector with forced mixing function are respectively connected to the Luer connectors of the syringes prefilled with cross-linked hyaluronic acid and prefilled hydroxyapatite microsphere powder; then, the plungers of the two syringes are pushed in turn to make the solid and liquid phase mixtures repeatedly pass through the hollow cavity 3 of the polycarbonate Luer multi-way connector with forced mixing function. When passing through the polycarbonate hollow cavity 3, the polycarbonate porous plate 5 is fixed, so that the solid and liquid phase mixtures of hydroxyapatite microsphere powder and cross-linked hyaluronic acid are forced to be squeezed out from the channels of 6 porous discs with through holes of 1 mm in diameter and flow between multiple porous discs under the action of shear force, so that materials of different densities are self-stirred to achieve uniform mixing and obtain a uniform mixture. It completely avoids external pollution and material waste, and a bubble-free and uniform mixture can be obtained within 1 minute, which can be used immediately after mixing, greatly shortening the surgical preparation time.

[0070] The following is an application example 3 of the present application in combination with specific circumstances. Figure 8 , Fig.10First, medical-grade polyetheretherketone is used to prepare a hollow cavity 3 and a screw 6 by injection molding, and the polyetheretherketone screw is installed in the polyetheretherketone hollow cavity 3 to form a polyetheretherketone forced mixing component 1; the polyetheretherketone screw 6 is arranged inside the polyetheretherketone hollow cavity 3, and when the mixture is forced to pass through the polyetheretherketone forced mixing component 1, the solid and liquid phases are forced to mix; the polyetheretherketone screw 6 is fixed in the polyetheretherketone hollow cavity 3; the inner surface of the polyetheretherketone hollow cavity 3 is a circular cylinder; the outer cylinder of the polyetheretherketone hollow cavity 3 is a plum blossom-shaped cylinder; both ends of the polyetheretherketone hollow cavity 3 are provided with external threads, and are respectively connected with the internal threads of the polyetheretherketone Luer connector 2, and the three are sequentially combined into an integrated polyetheretherketone Luer multi-channel connector with a forced mixing function.

[0071] Medical-grade α-tricalcium phosphate composite powder is filled into a syringe barrel pre-filled with solid phase powder, and disodium hydrogen phosphate aqueous solution is filled into a syringe barrel pre-filled with liquid phase. Together with a polyetheretherketone Luer multi-channel connector with forced mixing function, the kit is packaged and sterilized for marketing.

[0072] During clinical use, the solid-liquid mixing kit package is opened, and the Luer plugs on the two syringes pre-filled with α-tricalcium phosphate composite powder and the pre-filled with sodium hydrogen phosphate aqueous solution are respectively unplugged, and the Luer interfaces at both ends of the polyetheretherketone Luer multi-channel connector with a forced mixing function are respectively connected to the Luer connectors of the syringes pre-filled with sodium hydrogen phosphate aqueous solution and the pre-filled α-tricalcium phosphate composite powder; then, the plungers of the two syringes are pushed in turn to make the solid and liquid phase mixtures repeatedly pass through the hollow cavity 3 of the polyetheretherketone Luer multi-channel connector with a forced mixing function. When passing through the hollow cavity 3, the polyetheretherketone screw 6 is fixed relative to the hollow cavity 3, so that the solid and liquid phase mixtures of the α-tricalcium phosphate composite powder and the disodium hydrogen phosphate aqueous solution are forced to be squeezed out from the spiral channel and sheared, so that materials of different densities are quickly forced to stir and achieve uniform mixing, and a uniform mixture can be obtained within 1 minute, which greatly shortens the surgical preparation time.

[0073] The following is an application example 4 of the present application in combination with the specific situation. Figure 1-4 Medical-grade light-cured polyethylene resin was used to prepare a polyethylene Luer multi-channel connector with forced mixing function through one-time integral processing using additive manufacturing technology.

[0074] The calcium phosphate bone cement powder is filled into a syringe barrel pre-filled with solid phase powder, and the blending liquid is filled into a syringe barrel pre-filled with liquid phase. Together with an additively manufactured polyethylene Luer multi-channel connector with forced mixing function, the kit is packaged and sterilized for marketing.

[0075] During clinical use, the solid-liquid mixing kit package is opened, and the Luer plugs on the two syringes pre-filled with calcium phosphate bone cement powder and pre-filled with the blending liquid are respectively unplugged, and the Luer interfaces at both ends of the polyethylene Luer multi-channel connector with a forced mixing function are respectively connected to the Luer connectors of the syringes pre-filled with the blending liquid and pre-filled with calcium phosphate bone cement powder; then, the plunger rods of the two syringes are pushed in turn to make the solid-liquid mixture pass through the hollow cavity 3 of the polyethylene Luer multi-channel connector with a forced mixing function repeatedly for many times, so that the calcium phosphate bone cement powder and the blending liquid solid-liquid mixture are forced to be extruded in the spiral channel of the polyethylene Luer multi-channel connector with a forced mixing function, and under the action of shear force, the materials of different densities are quickly forced to stir and achieve uniform mixing, and a uniform mixture can be obtained within 0.5 minutes, which greatly shortens the surgical preparation time.

[0076] The utility model uses a Luer multi-channel connector with a forced mixing aid function, so that solid and liquid phases pre-filled in two syringes are conveniently, evenly and quickly mixed, and bubbles in the mixture are reduced, and external pollution and material waste are avoided. The mixture can be used immediately after mixing, and the utility model is particularly suitable for product applications in which solid and liquid phase materials are easily reacted and the reaction time is very short.

[0077] The above-described embodiments only express a certain implementation method of the utility model, and the description thereof is relatively specific and detailed, but it cannot be understood as limiting the scope of the patent of the utility model. It should be pointed out that, for ordinary technicians in this field, several modifications and improvements can be made without departing from the concept of the utility model, which all belong to the protection scope of the utility model. Therefore, the protection scope of the patent of the utility model shall be based on the attached claims.

Claims

1. A Ruhr multi-channel connector with a forced mixing aid function, characterized in that: The invention comprises a forced mixing component (1) and at least two Luer connectors (2); the forced mixing component (1) and the Luer connectors (2) are integrated into one body, and a channel is provided inside the forced mixing component, which passes through and communicates with any one of the Luer connectors (2) to any other one of the Luer connectors (2); The forced mixing component (1) comprises an I-shaped, Y-shaped, L-shaped, V-shaped or X-shaped hollow cavity (3), wherein a built-in mixing aid (4) is arranged in the hollow cavity (3); the Luer connector (2) is a male Luer connector or a female Luer connector or a combination thereof; at least two Luer connectors (2) are arranged outside the forced mixing component (1) and connected thereto; the central channel of the Luer connector (2) is connected to the hollow cavity (3) of the forced mixing component (1) to form a channel that allows multi-component liquids or slurries to be forced to flow through the built-in mixing aid (4) and be fully mixed.

2. A Luer multi-channel connector with a forced mixing aid function according to claim 1, characterized in that: The Luer connector (2) is three-dimensionally distributed around the forced mixing component (1), and the Luer connector (2) and the forced mixing component (1) are connected and assembled into one body by platform gluing, heat sealing or threaded interface connection, and the central axes of the Luer connectors (2) around the forced mixing component (1) are distributed at a three-dimensional angle greater than 0° and less than or equal to 180°.

3. A Luer multi-channel connector with a forced mixing aid function according to claim 1, characterized in that: The built-in mixing aid (4) is at least one relatively fixed porous plate (5) arranged in the hollow cavity (3); The porous plate (5) is evenly distributed with at least one circular, rectangular, polygonal, crescent-shaped or plum-shaped channel hole penetrating the porous plate (5); The porous plates (5) are arranged at intervals in the hollow cavity (3) and intersect with the symmetric central axis of the channel in the hollow cavity (3), gaps are left between the porous plates (5), and the symmetric centers of the channel holes on adjacent porous plates (5) are arranged in a staggered manner.

4. A Luer multi-channel connector with a forced mixing aid function according to claim 1, characterized in that: The built-in mixing aid (4) is at least one relatively fixed screw (6) or at least one screw (6) that can be forced to rotate around its central axis and is arranged in the hollow cavity (3). The central axis of the screw (6) is embedded in the connection between the Luer connector (2) and the hollow cavity (3).

5. A Luer multi-channel connector with a forced mixing aid function according to claim 1, characterized in that: The inner surface of the hollow cavity (3) is a circular cylinder or a polygonal cylinder, forming a smooth inner surface channel; the outer surface of the hollow cavity (3) is a circular cylinder, a polygonal cylinder or a plum blossom-shaped cylinder, which envelops the outer contour of the hollow cavity (3) into an I-shaped, Y-shaped, L-shaped, V-shaped or X-shaped shape.

6. A Luer multi-channel connector with a forced mixing aid function according to claim 1, characterized in that: The Luer connector (2) or the forced mixing component (1) are respectively prepared by injection molding and then assembled into one piece by gluing, heat sealing or threading.

7. A Luer multi-channel connector with a forced mixing aid function according to claim 1, characterized in that: The Luer connector (2) or the forced mixing component (1) is integrally manufactured in one go using additive manufacturing technology.

8. A mixing kit of a Ruhr multi-channel connector with a forced mixing aid function, characterized in that: A Luer multi-channel connector with a forced mixing aid function according to any one of claims 1 to 7, wherein the Luer multi-channel connector with a forced mixing aid function is connected to at least two pre-filled solid phase or pre-filled liquid phase syringes, and the central axes of the pre-filled solid phase or liquid phase syringes are distributed around the Luer multi-channel connector with a forced mixing aid function at a solid angle greater than 0° and less than or equal to 180°.

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