Chromatographic column sealing device

Abstract

The utility model provides a chromatographic column sealing device, and belongs to the technical field of chromatographic columns. The chromatographic column sealing device comprises a chromatographic column and a sealing assembly. The top end of the chromatographic column is fixedly sleeved with a first connecting sleeve, during use, the limiting rod is slidably inserted into the second connecting sleeve, then the second connecting sleeve is fixed, when the second connecting sleeve needs to be detached, the limiting rod is pulled to move in the direction away from the chromatographic column, then the second connecting sleeve can be pulled upwards, and the second connecting sleeve can be detached. The second connecting sleeve, an elastic sealing sleeve and a first elastic sealing ring are all inserted into the first connecting sleeve, a limiting rod is inserted into the second connecting sleeve so that the second connecting sleeve can be fixed, and then the limiting rod is pulled so that the second connecting sleeve can be mounted or dismounted; therefore, the chromatographic column can be sealed or opened, so that the sealing and opening of the chromatographic column are labor-saving and trouble-saving.

Description

Technical Field

[0001] The present application relates to the field of chromatography columns, and in particular, to a chromatography column sealing device. Background Art

[0002] Gel chromatography, also known as molecular sieve chromatography, refers to a technique in which components of a mixture are separated according to their molecular sizes when the mobile phase passes through a gel chromatography column. The chromatography column is the main body of gel chromatography technology, and is generally made of glass tubes or plexiglass tubes. The diameter of the chromatography column does not affect the separation degree. When the sample amount is large, the diameter of the column can be increased. In the relevant chromatography column technology, the top sealing structure of the chromatography column is connected and fixed by threads, but the threaded connection needs to be tightened to complete the fixation, and it needs to be rotated forcefully to complete the disassembly, which makes the sealing and opening of the chromatography column laborious and troublesome. Utility Model Content

[0003] In order to make up for the above shortcomings, the present application provides a chromatography column sealing device, which aims to improve the problem that the sealing and opening of the chromatography column are laborious and time-consuming.

[0004] An embodiment of the present application provides a chromatography column sealing device, comprising a chromatography column and a sealing assembly.

[0005] The top fixing sleeve of the chromatography column is provided with a first connecting sleeve, a limiting rod is slidably inserted inside the first connecting sleeve, the rod body of the limiting rod is provided with a spring, and the spring is fixedly connected to the first connecting sleeve.

[0006] The sealing assembly includes a second connecting sleeve, an elastic sealing sleeve, and a first elastic sealing ring. The elastic sealing sleeve is connected to the interior of the second connecting sleeve. The first elastic sealing ring is fixedly sleeved on the exterior of the second connecting sleeve. The second connecting sleeve, the elastic sealing sleeve and the first elastic sealing ring are all slidably inserted in the interior of the first connecting sleeve. The elastic sealing sleeve is slidably sleeved on the top of the chromatography column. The elastic sealing sleeve is tightly pressed against the chromatography column. The first elastic sealing ring is tightly pressed against the inner wall of the first connecting sleeve. The limiting rod is slidably inserted in the interior of the second connecting sleeve.

[0007] In a specific implementation, two limit rods are provided, one end of each of the limit rods is slidably inserted into the interior of the first connecting sleeve, and the rod bodies of the two limit rods are slidably penetrated through the sleeve wall of the first connecting sleeve.

[0008] In a specific implementation manner, the two limiting rods are symmetrically arranged, and a connecting plate is provided at one end of the two limiting rods away from the interior of the first connecting sleeve.

[0009] In a specific embodiment, the spring is provided on one side of the two connecting plates, one end of the two springs away from the connecting plates is fixedly connected to the outer wall of the first connecting sleeve, and the spring is slidably sleeved on the rod body of the limiting rod.

[0010] In a specific implementation manner, the rod bodies of the two limiting rods are slidably penetrated through the ring wall of the first elastic sealing ring, and one ends of the two limiting rods are slidably inserted into the interior of the second connecting sleeve.

[0011] In a specific embodiment, the chromatography column sealing device also includes an extrusion assembly, which includes a threaded sleeve, a threaded rod and an extrusion plate, wherein the threaded sleeve is fixedly penetrated through the center of the second connecting sleeve and the top wall of the elastic sealing sleeve, the threaded rod is threadedly penetrated through the interior of the threaded sleeve, the extrusion plate slides inside the chromatography column, and the center of the upper surface of the extrusion plate is rotationally connected to the bottom end of the threaded rod.

[0012] In a specific embodiment, the bottom end of the threaded rod is rotatably inserted into the interior of the chromatography column, and the top end of the threaded rod is provided with a rotating hand wheel.

[0013] In a specific embodiment, the external fixed sleeve of the extrusion plate is provided with a second elastic sealing ring, and the outer wall of the second elastic sealing ring is slidably fitted with the inner wall of the chromatography column.

[0014] The beneficial effect of the utility model is that the utility model obtains a chromatography column sealing device through the above design, when in use, the limiting rod passes through the sleeve wall of the first connecting sleeve, the limiting rod is slidably inserted into the interior of the second connecting sleeve, the spring will limit and fix the limiting rod, and then fix the second connecting sleeve. When the second connecting sleeve needs to be disassembled, the limiting rod is pulled in the direction away from the chromatography column to move, the limiting rod can be pulled out of the interior of the second connecting sleeve and the first elastic sealing ring, and then the second connecting sleeve can be pulled upward, the second connecting sleeve can be pulled out of the interior of the first connecting sleeve, and then the disassembly of the second connecting sleeve is completed, the second connecting sleeve, the elastic sealing sleeve and the first elastic sealing ring are all inserted into the interior of the first connecting sleeve, the limiting rod is inserted into the interior of the second connecting sleeve to fix the second connecting sleeve, and then the limiting rod can be pulled to install or disassemble the second connecting sleeve, and then the chromatography column can be sealed or opened, making the sealing and opening of the chromatography column more labor-saving and trouble-free. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] In order to more clearly illustrate the technical solutions of the implementation methods of the present application, the drawings required for use in the implementation methods will be briefly introduced below. It should be understood that the following drawings only show certain embodiments of the present application and therefore should not be regarded as limiting the scope. For ordinary technicians in this field, other related drawings can be obtained based on these drawings without paying creative work.

[0016] Figure 1 It is a schematic diagram of the structure of a chromatography column sealing device provided in an embodiment of the present application;

[0017] Figure 2 A schematic diagram of the cross-sectional structure of a chromatography column sealing device provided in an embodiment of the present application;

[0018] Figure 3 A schematic diagram of the structure of the first connecting sleeve and the limiting rod provided in the embodiment of the present application;

[0019] Figure 4 A schematic diagram of the cross-sectional structure of a sealing assembly provided in an embodiment of the present application.

[0020] In the figure: 100-chromatographic column; 110-first connecting sleeve; 120-limiting rod; 121-connecting plate; 130-spring; 200-sealing assembly; 210-second connecting sleeve; 220-elastic sealing sleeve; 230-first elastic sealing ring; 300-extrusion assembly; 310-threaded sleeve; 320-threaded rod; 321-rotating hand wheel; 330-extrusion plate; 331-second elastic sealing ring. DETAILED DESCRIPTION

[0021] The technical solutions in the embodiments of the present application will be described below in conjunction with the drawings in the embodiments of the present application.

[0022] In order to make the purpose, technical solutions and advantages of the implementation methods of this application clearer, the technical solutions in the implementation methods of this application will be clearly and completely described below in conjunction with the drawings in the implementation methods of this application. Obviously, the described implementation methods are part of the implementation methods of this application, not all of the implementation methods. Based on the implementation methods in this application, all other implementation methods obtained by ordinary technicians in this field without creative work are within the scope of protection of this application.

[0023] See also Figure 1 The present application provides a chromatography column sealing device, including a chromatography column 100 and a sealing assembly 200.

[0024] See also Figure 1-3A first connecting sleeve 110 is fixedly sleeved on the top of the chromatography column 100, and a limiting rod 120 is slidably inserted inside the first connecting sleeve 110. Two limiting rods 120 are provided, and one end of the two limiting rods 120 is slidably inserted into the inside of the first connecting sleeve 110. The rod bodies of the two limiting rods 120 slide through the sleeve wall of the first connecting sleeve 110. The two limiting rods 120 are symmetrically arranged, and a connecting plate 121 is provided at one end of the two limiting rods 120 away from the inside of the first connecting sleeve 110.

[0025] In the present application, the rod body of the limiting rod 120 is provided with a spring 130, and the spring 130 is fixedly connected to the first connecting sleeve 110. One side of the two connecting plates 121 is provided with a spring 130, and one end of the two springs 130 away from the connecting plates 121 is fixedly connected to the outer wall of the first connecting sleeve 110, and the spring 130 is slidably sleeved on the rod body of the limiting rod 120.

[0026] See also Figure 1-4 The sealing assembly 200 includes a second connecting sleeve 210, an elastic sealing sleeve 220, and a first elastic sealing ring 230. The elastic sealing sleeve 220 is connected to the inside of the second connecting sleeve 210. The elastic sealing sleeve 220 can be an elastic rubber sleeve. The first elastic sealing ring 230 is fixedly sleeved on the outside of the second connecting sleeve 210. The first elastic sealing ring 230 can be an elastic rubber ring. The second connecting sleeve 210, the elastic sealing sleeve 220 and the first elastic sealing ring 230 are all slidably inserted into the inside of the first connecting sleeve 110.

[0027] In this embodiment, the elastic sealing sleeve 220 is slidably sleeved on the top of the chromatography column 100, the elastic sealing sleeve 220 is tightly pressed against the chromatography column 100, the first elastic sealing ring 230 is tightly pressed against the inner wall of the first connecting sleeve 110, the limiting rod 120 is slidably inserted into the interior of the second connecting sleeve 210, the rod bodies of the two limiting rods 120 are slidably inserted into the circle wall of the first elastic sealing ring 230, and one end of the two limiting rods 120 is slidably inserted into the interior of the second connecting sleeve 210.

[0028] See also Figure 1-4 The chromatography column sealing device also includes an extrusion assembly 300, which includes a threaded sleeve 310, a threaded rod 320 and an extrusion plate 330. The threaded sleeve 310 is fixedly penetrated through the center of the second connecting sleeve 210 and the top wall of the elastic sealing sleeve 220, and the threaded rod 320 is threadedly penetrated through the inside of the threaded sleeve 310. The bottom end of the threaded rod 320 is rotatably inserted into the inside of the chromatography column 100, and a rotating hand wheel 321 is provided at the top of the threaded rod 320.

[0029] In the specific setting, the extrusion plate 330 slides inside the chromatography column 100, and the external fixed sleeve of the extrusion plate 330 is provided with a second elastic sealing ring 331. The outer wall of the second elastic sealing ring 331 slides and fits with the inner wall of the chromatography column 100. The second elastic sealing ring 331 can be an elastic rubber ring. The center of the upper surface of the extrusion plate 330 is rotatably connected to the bottom end of the threaded rod 320.

[0030] Specifically, the working principle of the chromatography column sealing device is as follows: when in use, the two limiting rods 120 penetrate the sleeve wall of the first connecting sleeve 110, and the two limiting rods 120 are slidably inserted into the interior of the second connecting sleeve 210. The spring 130 will limit and fix the limiting rods 120, and then fix the second connecting sleeve 210. When the second connecting sleeve 210 needs to be disassembled, the two connecting plates 121 are pulled away from the chromatography column 100, and the connecting plates 121 stretch the spring 130, and the connecting plates 121 drive the limiting rods 120 to move, so that the limiting rods 120 can be pulled out of the second connecting sleeve 210 and the first elastic sealing ring 230. , and then the second connecting sleeve 210 can be pulled upwards to pull the second connecting sleeve 210 out of the first connecting sleeve 110, thereby completing the disassembly of the second connecting sleeve 210, inserting the second connecting sleeve 210, the elastic sealing sleeve 220 and the first elastic sealing ring 230 into the first connecting sleeve 110, inserting the limiting rod 120 into the second connecting sleeve 210 to fix the second connecting sleeve 210, and then pulling the limiting rod 120 to install or disassemble the second connecting sleeve 210, and then the chromatography column 100 can be sealed or opened, making it easier and more convenient to open the seal of the chromatography column 100.

[0031] The above description is only an embodiment of the present application and is not intended to limit the scope of protection of the present application. For those skilled in the art, the present application may have various changes and variations. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present application should be included in the scope of protection of the present application. It should be noted that similar reference numerals and letters represent similar items in the following drawings, so once an item is defined in one drawing, it does not need to be further defined and explained in the subsequent drawings.

[0032] The above is only a specific implementation of the present application, but the protection scope of the present application is not limited thereto. Any technician familiar with the technical field can easily think of changes or substitutions within the technical scope disclosed in the present application, which should be included in the protection scope of the present application. Therefore, the protection scope of the present application should be based on the protection scope of the claims.

Claims

1. A chromatography column sealing device, characterized in that: include A chromatography column (100), wherein a first connecting sleeve (110) is fixedly mounted on the top of the chromatography column (100), a limiting rod (120) is slidably inserted into the interior of the first connecting sleeve (110), a rod body of the limiting rod (120) is provided with a spring (130), and the spring (130) is fixedly connected to the first connecting sleeve (110); A sealing assembly (200), the sealing assembly (200) comprising a second connecting sleeve (210), an elastic sealing sleeve (220), and a first elastic sealing ring (230), the elastic sealing sleeve (220) being connected to the interior of the second connecting sleeve (210), the first elastic sealing ring (230) being fixedly sleeved on the exterior of the second connecting sleeve (210), the second connecting sleeve (210), the elastic sealing sleeve (220), and the first elastic sealing ring (230) being slidably inserted into the interior of the first connecting sleeve (110), the elastic sealing sleeve (220) being slidably sleeved on the top end of the chromatography column (100), the elastic sealing sleeve (220) being tightly pressed against the chromatography column (100), the first elastic sealing ring (230) being tightly pressed against the inner wall of the first connecting sleeve (110), and the limiting rod (120) being slidably inserted into the interior of the second connecting sleeve (210).

2. A chromatography column sealing device according to claim 1, characterized in that: Two limit rods (120) are provided, one end of each of the limit rods (120) is slidably inserted into the interior of the first connecting sleeve (110), and the rod bodies of the two limit rods (120) are slidably penetrated through the sleeve wall of the first connecting sleeve (110).

3. A chromatography column sealing device according to claim 2, characterized in that: The two limiting rods (120) are symmetrically arranged, and a connecting plate (121) is provided at one end of the two limiting rods (120) away from the interior of the first connecting sleeve (110).

4. A chromatography column sealing device according to claim 3, characterized in that: The spring (130) is disposed on one side of the two connecting plates (121); one end of the two springs (130) away from the connecting plates (121) is fixedly connected to the outer wall of the first connecting sleeve (110); and the spring (130) is slidably sleeved on the rod body of the limiting rod (120).

5. A chromatography column sealing device according to claim 2, characterized in that: The rod bodies of the two limiting rods (120) are slidably inserted into the wall of the first elastic sealing ring (230), and one end of the two limiting rods (120) is slidably inserted into the interior of the second connecting sleeve (210).

6. A chromatography column sealing device according to claim 1, characterized in that: The invention also comprises an extrusion assembly (300), wherein the extrusion assembly (300) comprises a threaded sleeve (310), a threaded rod (320) and an extrusion plate (330), wherein the threaded sleeve (310) is fixedly passed through the center of the top wall of the second connecting sleeve (210) and the elastic sealing sleeve (220), the threaded rod (320) is threadedly passed through the interior of the threaded sleeve (310), the extrusion plate (330) slides inside the chromatography column (100), and the center of the upper surface of the extrusion plate (330) is rotatably connected to the bottom end of the threaded rod (320).

7. A chromatography column sealing device according to claim 6, characterized in that: The bottom end of the threaded rod (320) is rotatably inserted into the interior of the chromatography column (100), and the top end of the threaded rod (320) is provided with a rotating hand wheel (321).

8. A chromatography column sealing device according to claim 7, characterized in that: The external fixed sleeve of the extrusion plate (330) is provided with a second elastic sealing ring (331), and the outer wall of the second elastic sealing ring (331) is slidably fitted with the inner wall of the chromatography column (100).

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