Perfusion fixing device for animal experiment

Abstract

The utility model discloses a perfusion fixing device for animal experiments. The perfusion fixing device comprises a base; two first threaded cylinders are arranged on the first threaded rod; each second threaded rod is provided with two second threaded cylinders; the supporting plate is arranged between the pair of second threaded rods; and the head fixing plate is arranged at the top of the base. According to the perfusion fixing device provided by the utility model, the positions of the four limb fixing pieces, the position of the head fixing piece and the height of the supporting plate can be adjusted according to the body sizes of laboratory mice, so that the laboratory mice with different body sizes can be stably clamped, and the application range of the perfusion fixing device is greatly expanded; the device can be widely popularized and applied in the field of animal experiment equipment.

Description

Technical Field

[0001] The utility model relates to the technical field of animal experiment equipment, and more specifically, to a perfusion fixing device used for animal experiments. Background Art

[0002] When conducting animal perfusion experiments, it is usually necessary to fix the animals. For example, when performing inferior vena cava perfusion on experimental mice, the various positions of the experimental mice need to be fixed on the fixator in sequence to avoid the experimental mice biting the staff due to bare hand operation during the experimental operation. For example, the utility model patent with authorization announcement number CN209285805U discloses a dual-purpose fixator for intraperitoneal injection and tail vein injection of mice, which includes a shell, and fixing holes and fixing columns arranged at various positions on the shell. The setting positions of the fixing parts of the above patent are fixed and cannot be adjusted, which cannot be applied to experimental mice of different sizes, and is not conducive to the promotion and use of perfusion fixators. Utility Model Content

[0003] An object of the present invention is to solve at least the above problems and to provide at least the advantages which will be described below.

[0004] Another object of the utility model is to provide a perfusion fixing device for animal experiments, which can flexibly adjust the positions of various fixing parts according to the size of the experimental mice, thereby increasing the application scope of the perfusion fixing device and facilitating the promotion and application of the perfusion fixing device in animal experiments.

[0005] In order to achieve these purposes and other advantages according to the utility model, a perfusion fixation device for animal experiments is provided, which includes:

[0006] A base, which is a hollow cubic structure with an open top;

[0007] A first threaded rod, both ends of which are rotatably connected to two side walls spaced apart in the length direction of the base, the first threaded rod is provided with two first threaded sections with opposite spiral directions, each first threaded section is provided with a first threaded barrel for rotatable sleeve, and the rotation of the first threaded rod drives the two first threaded barrels to move horizontally along the length direction of the base;

[0008] A pair of second threaded rods, each second threaded rod extends along the width direction of the base, and both ends are rotatably connected to the first slider, each first slider is slidably connected to the side wall of the base along the length direction of the base; each second threaded rod is provided with two second threaded sections with opposite spirals, each second threaded section is threadedly rotatably sleeved with a second threaded cylinder, and the rotation of the second threaded rod drives the two second threaded cylinders to move horizontally along the width direction of the base; each second threaded cylinder is connected to the corresponding first slider through the first telescopic rod; each second threaded cylinder is provided with a limb clamping plate, each limb clamping plate is provided with a limb fixing piece for fixing the limb, and the middle part of each second threaded rod is rotatably connected to the top of a first threaded cylinder;

[0009] A support plate, which is horizontally arranged between a pair of second threaded rods, and the bottom of the support plate is connected to the bottom surface of the base through a vertically arranged second telescopic rod;

[0010] A head fixing plate is slidably arranged on the top of the base along the length direction of the base and is located at one end of the first threaded rod. A head fixing piece is arranged on the head fixing plate.

[0011] Preferably, in the perfusion fixture for animal experiments, a collar with an axis perpendicular to the axis of the first threaded rod is fixed on the top of each first threaded barrel, and each second threaded rod is coaxially threadedly rotatably sleeved in the corresponding collar.

[0012] Preferably, in the perfusion fixation device for animal experiments, the support plate includes a first plate body and two second plate bodies respectively arranged on both sides of the first plate body, each second plate body is slidably connected to the first plate body along the length direction of the base, and the side portion of each second plate body is connected to the adjacent first threaded cylinder through an L-shaped first connecting rod, and the vertical portion of the first connecting rod is a telescopic structure.

[0013] Preferably, in the perfusion fixation device for animal experiments, one side of the head fixation plate is connected to an adjacent first threaded cylinder via an L-shaped second connecting rod.

[0014] Preferably, in the perfusion fixation device for animal experiments, an inflatable air bag is provided on the upper surface of the first plate body and each second plate body.

[0015] Preferably, in the perfusion fixation device for animal experiments, two bellows are sleeved on each second threaded rod, a bellows is correspondingly arranged between a second threaded cylinder and a collar, and both ends of each bellows are respectively connected to the second threaded cylinder and the collar.

[0016] The utility model at least has the following beneficial effects:

[0017] The perfusion fixing device provided by the utility model can adjust the positions of the four limb fixing parts, the position of the head fixing part, and the height of the support plate according to the body size of the experimental mouse, so as to achieve stable fixing of experimental mice of different body sizes, greatly improving the application scope of the perfusion fixing device, and can be vigorously promoted and applied in the field of animal experimental equipment.

[0018] Other advantages, objectives and features of the present invention will be embodied in part through the following description, and in part will be understood by those skilled in the art through research and practice of the present invention. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 It is a top view of the perfusion fixation device for animal experiments described in one of the technical solutions of the utility model;

[0020] Figure 2 It is a top view of the interior of the base of the perfusion fixture for animal experiments described in one of the technical solutions of the utility model;

[0021] Figure 3 For this utility model Figure 1 Sectional view of AA in the middle;

[0022] Figure 4 For this utility model Figure 2 Cross-sectional view of BB.

[0023] Explanation of the markings in the specification: 1-base, 2-first threaded rod; 21-first threaded cylinder, 22-ring, 3-second threaded rod; 31-second threaded cylinder, 32-first slider, 33-first telescopic rod, 34-limb clamping plate, 35-limb fixing piece, 36-bellows, 4-support plate, 41-second telescopic rod, 42-first connecting rod, 5-head fixing plate, 51-head fixing piece, 52-second connecting rod, 61-first gear plate, 62-first rotating shaft, 63-first rotating handle, 64-second gear plate, 71-third gear plate, 72-second slider, 73-second rotating shaft, 74-second rotating handle, 75-fourth gear plate. DETAILED DESCRIPTION

[0024] The present invention will be further described in detail below in conjunction with the accompanying drawings and embodiments so that those skilled in the art can implement the invention with reference to the description.

[0025] It should be understood that the terms such as “having”, “including” and “comprising” used herein do not exclude the existence or addition of one or more other elements or combinations thereof.

[0026] It should be noted that the experimental methods described in the following embodiments are conventional methods unless otherwise specified, and the reagents and materials can be obtained from commercial channels unless otherwise specified.

[0027] In the description of the present invention, terms such as "lateral", "longitudinal", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside" and "outside" indicate directions or positional relationships based on the directions or positional relationships shown in the accompanying drawings. They are only for the convenience of describing the present invention and simplifying the description. They do not indicate or imply that the device or element referred to must have a specific direction, be constructed and operated in a specific direction, and therefore cannot be understood as a limitation on the present invention.

[0028] like Figures 1 to 4 As shown, the utility model provides a perfusion fixation device for animal experiments, which includes:

[0029] A base 1, which is a hollow cubic structure with an open top;

[0030] The first threaded rod 2, both ends of which are rotatably connected to the two side walls spaced apart in the length direction of the base 1, the first threaded rod 2 is provided with two first threaded sections with opposite spiral directions, each first threaded section is provided with a first threaded barrel 21 for threaded rotation, the rotation of the first threaded rod 2 drives the two first threaded barrels 21 to move horizontally along the length direction of the base 1 (specifically, a sleeve is provided on the second threaded barrel, and the first threaded rod is sleeved in the bearing of the sleeve, so that the first threaded barrel will not rotate with the first threaded rod, so that the rotation of the first threaded rod can drive the linear movement of the first threaded barrel), and the movement directions of the two first threaded barrels are opposite; a sleeve 22 with an axis perpendicular to the axis of the first threaded rod 2 is fixed on the top of each first threaded barrel 21;

[0031] A pair of second threaded rods 3, each second threaded rod 3 is coaxially rotatably sleeved in a sleeve ring 22 through a bearing, and the two ends of each second threaded rod 3 are rotatably connected with a first slider 32, and each first slider 32 is slidably connected with the side wall of the base 1 along the length direction of the base 1; each second threaded rod 3 is provided with two second threaded sections with opposite spirals, and each second threaded section is threadedly sleeved with a second threaded cylinder 31, and the rotation of the second threaded rod 3 drives the two second threaded cylinders 31 to move horizontally along the width direction of the base 1, and makes the movement directions of the second threaded cylinders opposite; each second threaded cylinder 31 is connected to the corresponding first slider 32 through a first telescopic rod 33; each second threaded cylinder 31 is provided with a limb clamping plate 34, and each limb clamping plate 34 is provided with a limb fixing piece 35 for fixing the animal limbs; the middle part of each second threaded rod 3 is rotatably connected with the corresponding first threaded cylinder 21 through a sleeve, so that the second threaded rod can move along the length direction of the base following the first threaded cylinder, and can also rotate around its own axis;

[0032] A support plate 4 is horizontally arranged between a pair of second threaded rods 3, and the bottom of the support plate 4 is connected to the bottom surface of the base 1 through a vertically arranged second telescopic rod 41;

[0033] The head fixing plate 5 is slidably disposed on the top of the base 1 along the length direction of the base 1 and is located at one end of the first threaded rod 2 . A head fixing member 51 is disposed on the head fixing plate 5 .

[0034] In the above technical solution, the utility model provides a perfusion fixing device for animal experiments, which includes a base 1, a first threaded rod 2 is horizontally rotatably arranged inside the base 1, and the first threaded rod 2 is arranged along the length direction of the base 1 ( Figure 1For example, the left-right direction is the length direction of the base 1, and the up-down direction is the width direction of the base 1), the first threaded rod 2 is arranged in the middle of the base 1, and the two ends of the first threaded rod 2 are rotatably connected with the inner side wall of the base 1 (the two inner side walls in the length direction of the base 1), and the circumferential side surface of the first threaded rod 2 is provided with two first threaded segments with opposite spiral directions, and each first threaded segment is threadedly rotatably sleeved with a first threaded barrel 21, and the inner wall of each first threaded barrel 21 is provided with a first internal thread matched with the first external threaded segment, so that when the first threaded rod 2 rotates circumferentially around its own axis, it drives The two first threaded cylinders 21 move horizontally and linearly along the axis of the first threaded rod 2, and the rotation of the first threaded rod 2 drives the two first threaded cylinders 21 to move horizontally in opposite directions, so that the spacing between the two second threaded rods 3 can be adjusted. A collar 22 is fixed on the top of each first threaded cylinder 21, and its axis is horizontally arranged and perpendicular to the axis of the first threaded rod 2. A second threaded rod 3 is rotatably sleeved (bearing) in each collar 22. Each second threaded rod 3 extends horizontally along the width direction of the base 1. The two ends of the second threaded rod 3 are rotatably connected to a first slider 32 respectively. Each first slider The block 32 is slidably connected with the inner side wall of the base 1 (the two inner side walls in the width direction of the base 1) along the length direction of the base 1. The sliding of the first threaded tube 21 along the length direction of the base 1 can drive the second threaded rod 3 to slide along the length direction of the base 1. At the same time, the second threaded rod 3 can rotate around its own axis. Each second threaded rod 3 is provided with two second threaded sections with opposite spiral directions at intervals along its length direction. A second threaded tube is provided on each second threaded section for threaded rotation. The two second threaded tubes are respectively located at the two ends of the corresponding collar 22. Both sides of each second threaded tube 31 are connected by A horizontally arranged first telescopic rod 33 is connected to the first slider 32, which can limit the circumferential rotation of the second threaded cylinder 31, so that the rotation of each second threaded rod 3 drives the two second threaded cylinders 31 to move in the opposite direction or in the opposite direction along the width direction of the base 1, thereby adjusting the spacing of the second threaded cylinders 31 arranged in pairs, and a limb clamping plate 34 is arranged on each second threaded cylinder 31, and a limb fixing piece 35 is arranged on the limb clamping plate 34, which can be realized by existing technical means, such as a strap or a buckle that can be opened and locked, etc. The limbs of the experimental mouse can be fixed by the limb fixing piece 35;A support plate 4 is further provided, which is located between a pair of second threaded rods 3. The support plate 4 is used to abut against the back (supine) or abdomen (prone) of the experimental mouse, so as to support the body of the experimental mouse. The support plate 4 is connected to the bottom surface of the base 1 by a vertically arranged second telescopic rod 41 (an electric telescopic rod can be selected). The height of the support plate 4 can be adjusted to adapt to experimental mice of different fat and thin sizes, so as to ensure the stable fixation of the experimental mouse. A head fixing plate 5 is provided on the top of the base 1 for sliding along the length direction of the base 1, which is used to support the head of the experimental mouse. A head fixing member 51 (which can also be a neck fixing member, and the head fixing member 51 and the neck fixing member are both realized by existing technical means, such as a strap or a buckle that can be opened and locked, etc.) is provided on the head fixing plate 5 to achieve the fixation of the head of the experimental mouse. Preferably, the head fixing member 51 is slidably provided on the head fixing plate 5 along the length direction of the base 1, and the position of the head fixing member 51 can be accurately adjusted according to the neck length of the experimental mouse.

[0035] The perfusion fixing device provided by the utility model can adjust the positions of the four limb fixing parts 35, the position of the head fixing part 51, and the height of the support plate 4 according to the body size of the experimental mouse, so as to achieve stable fixing of experimental mice of different body sizes, greatly improving the application scope of the perfusion fixing device, and can be vigorously promoted and applied in the field of animal experimental equipment.

[0036] In actual use, the first threaded rod 2 can be rotated according to the size of the experimental mouse, and the spacing between the two second threaded rods 3 can be adjusted so that the two second threaded rods 3 correspond to the upper limbs and lower limbs of the experimental mouse respectively. Then, the spacing between the two limb fixing members 35 arranged in pairs can be adjusted by rotating the second threaded rods 3 respectively so that the positions of the four limb fixing members 35 correspond to the limbs of the experimental mouse one by one. Then, the height of the support plate 4 can be adjusted, and the position of the head fixing member 51 can be adjusted. The body of the mouse can be placed on the support plate 4, and the head can be placed on the head fixing plate 5. The four limbs can be fixed respectively by the limb fixing members 35, and the head can be fixed by the head fixing member 51. The rotation of the first threaded rod 2 and the second threaded rod 3 can be manual rotation, or a motor can be set to drive.

[0037] In another technical solution, in the perfusion fixture for animal experiments, the other end of the first threaded rod 2 passes through the side wall of the base 1 and extends to the outside of the base 1; the fixture further includes a first rotating mechanism, which includes:

[0038] A first gear plate 61, which is coaxially fixedly sleeved on the other end of the first threaded rod 2;

[0039] A first rotating shaft 62, which is parallel to the first threaded rod 2 and rotatably connected to the side wall of the base 1; a first rotating handle 63 is provided at the end of the first rotating shaft 62;

[0040] The second gear plate 64 is coaxially fixedly sleeved on the first rotating shaft 62 and meshed with the first gear plate 61 .

[0041] In the above technical scheme, the utility model provides a method for realizing the rotation of the first threaded rod 2. Specifically, a first gear plate 61 is fixedly mounted on the other end of the first threaded rod 2, a first rotating shaft 62 is rotatably mounted on the side wall of the base 1 corresponding to the other end of the first threaded rod 2, and a second gear plate 64 engaged with the first gear plate 61 is fixedly mounted on the first rotating shaft 62. The first rotating shaft 62 is rotated by holding a first rotating handle 63 on the first rotating shaft 62, thereby driving the rotation of the first threaded rod 2. As a preferred scheme, a first motor can also be provided, whose output shaft is coaxially connected to the first rotating shaft 62 and driven by the first motor.

[0042] In another technical solution, the perfusion fixing device for animal experiments, the side wall of the base is provided with two first strip-shaped through holes extending along the length direction of the base, one end of a second threaded rod is correspondingly provided with a first strip-shaped through hole, the first strip-shaped through hole is for the second rotating shaft to pass through and enables the second threaded rod to move along the length direction of the base, one end of the second threaded rod rotates through the first slider, passes through the first strip-shaped through hole, and extends to the outside of the base; the fixing device also includes a second rotating mechanism, which includes:

[0043] Two third gear plates 71, one end of a second threaded rod 3 is coaxially fixedly sleeved with a third gear plate 71;

[0044] A second slider 72, which is slidably disposed on the inner wall of the base 1 along the length direction of the base 1, and the second slider is located between the two second threaded rods;

[0045] A second rotating shaft 73 is arranged parallel to the second threaded rod 3, one end of the second rotating shaft 73 is rotatably connected to the second slider 72, and the other end passes through a second strip-shaped through hole arranged on the side wall of the base 1 and is fixed with a second rotating handle 74; the second strip-shaped through hole is located above the two first strip-shaped through holes and does not interfere with the first strip-shaped through holes, and the second rotating shaft passes through the second strip-shaped through hole and allows the second rotating shaft to move along the length direction of the base;

[0046] The fourth gear plate 75 is coaxially fixedly sleeved on the other end of the second rotating shaft 73 and can be meshed with any third gear plate 71 .

[0047] In the above technical solution, the utility model provides a method for realizing the rotation of the two second threaded rods 3. Specifically, on the side wall of the base, Figure 1Two first strip-shaped through holes are provided on the middle and upper side walls, through which the two second threaded rods pass respectively, so that when the first threaded rod rotates to drive the first threaded tube to move along the length direction of the base, the second threaded rod can move along the length direction of the base in the first strip-shaped through hole, and the second threaded rod can rotate around its own axis relative to the base; a second strip-shaped through hole is also provided on the side wall of the base for the second rotating shaft to pass through, which is located above the first strip-shaped through hole, and the second strip-shaped through hole and the two first strip-shaped through holes do not interfere with each other. The second strip-shaped through hole allows the second rotating shaft to move along the length direction of the base, and the second rotating shaft can also rotate around its own axis, and a third gear disk 71 is fixedly sleeved on each second threaded rod 3, and a fourth gear disk 75 that can selectively mesh with the two third gear disks 71 is provided between the two third gear disks 71, and the fourth gear disk 75 is fixedly sleeved on the second rotating shaft 73, and the second rotating shaft 73 is rotatably connected to the second sliding The second slider 72 is arranged on the inner side wall of the base 1 and slides along the length direction of the base 1, so that the second shaft 73 (the second shaft can slide along the second strip-shaped through hole) and the fourth gear plate 75 can be slid along the length direction of the base 1, and the fourth gear plate 75 can be moved to a position close to the second threaded rod 3 that needs to be rotated, and the fourth gear plate 75 can be meshed with the third gear plate 71 on the second threaded rod 3, and the second threaded rod 3 is driven to rotate by rotating the second shaft 73. When the other second threaded rod 3 needs to be rotated, the second shaft 73 and the fourth gear plate 75 are slid along the length direction of the base 1 until the fourth gear plate 75 is meshed with the third gear plate 71 on the other second threaded rod 3. Preferably, the second shaft 73 can be coaxially connected to the output shaft of the second motor, and the second motor can be arranged on the second slider 72, so that the same power source can selectively drive the rotation of the two second threaded rods 3.

[0048] In another technical solution, the perfusion fixing device for animal experiments, the support plate 4 includes a first plate body and two second plate bodies respectively arranged on both sides of the first plate body, each second plate body is slidably connected with the first plate body along the length direction of the base 1, and the side of each second plate body is connected with the adjacent first threaded cylinder 21 through an L-shaped first connecting rod 42, and the vertical part of the first connecting rod is a telescopic structure. In this technical solution, the support plate 4 is set as a structure that can be pulled and unfolded along the length direction of the base 1, and can be unfolded by moving the two first threaded cylinders 21 in a direction away from each other, and contracted by moving the two first threaded cylinders 21 in a direction close to each other, and the size of the support plate 4 along the length direction of the base 1 is adjusted in time, so that the bodies of experimental mice of different sizes can be effectively supported; the first connecting rod 42 is set as an L-shaped structure, which can make up for the height difference between the first threaded cylinder 21 and the support plate 4. Since the height of the support plate 4 needs to be adjusted, it is further necessary to set the vertical part of the first connecting rod 42 as a telescopic structure.

[0049] In another technical solution, in the perfusion fixation device for animal experiments, one side of the head fixing plate 5 is connected to an adjacent first threaded cylinder 21 via an L-shaped second connecting rod 52. The second connecting rod 52 connects one side of the head fixing plate 5 to an adjacent first threaded cylinder 21, and the head fixing plate 5 can be driven to move relative to the base 1 along the length direction of the base 1 under the movement of the first threaded cylinder 21. Furthermore, a slide groove is provided at the bottom of the head fixing plate 5 along the length direction of the base 1, and a slide groove is provided at the top of the base 1 ( Figure 1 A slider is provided at the top of the middle right side wall, and the slider is slidably arranged in the slide groove to slidably connect the head fixing plate 5 with the base 1.

[0050] In another technical solution, in the perfusion fixation device for animal experiments, the upper surfaces of the first plate and each second plate are provided with an inflatable airbag. The inflatable airbag is provided on the second plate, and the height difference between the upper surface of the second plate and the upper surface of the first plate can be compensated by inflation, and the upper surfaces of the first plate and the second plate can be better fitted to the back or abdomen of the experimental mouse.

[0051] In another technical solution, in the perfusion fixing device for animal experiments, two bellows 36 are movably sleeved on each second threaded rod 3, one bellows 36 is correspondingly arranged between a second threaded barrel 31 and a collar 22, and the two ends of each bellows 36 are respectively connected to the second threaded barrel 31 and the collar 22. A tensile bellows 36 with a certain degree of ductility is sleeved on each second threaded rod 3, such as a bellows made of PVC material, which can be stretched or shortened; it can protect the second threaded rod 3 and prevent the body of the experimental mouse from being scratched by contact with the second threaded rod 3.

[0052] The number of devices and processing scales described here are used to simplify the description of the utility model. Applications, modifications and variations of the utility model are obvious to those skilled in the art.

[0053] Although the implementation scheme of the utility model has been disclosed as above, it is not limited to the applications listed in the specification and implementation modes. It can be fully applied to various fields suitable for the utility model. For those familiar with the art, additional modifications can be easily implemented. Therefore, without departing from the general concept defined by the claims and the scope of equivalents, the utility model is not limited to the specific details and the illustrations shown and described herein.

Claims

1. A perfusion fixation device for animal experiments, characterized in that: include: A base, which is a hollow cubic structure with an open top; A first threaded rod, both ends of which are rotatably connected to two side walls spaced apart in the length direction of the base, the first threaded rod is provided with two first threaded sections with opposite spiral directions, each first threaded section is provided with a first threaded barrel for rotatable sleeve, and the rotation of the first threaded rod drives the two first threaded barrels to move horizontally along the length direction of the base; A pair of second threaded rods, each second threaded rod extends along the width direction of the base, and both ends are rotatably connected to the first slider, each first slider is slidably connected to the side wall of the base along the length direction of the base; each second threaded rod is provided with two second threaded sections with opposite spirals, each second threaded section is threadedly rotatably sleeved with a second threaded cylinder, and the rotation of the second threaded rod drives the two second threaded cylinders to move horizontally along the width direction of the base; each second threaded cylinder is connected to the corresponding first slider through the first telescopic rod; each second threaded cylinder is provided with a limb clamping plate, each limb clamping plate is provided with a limb fixing piece for fixing the limb, and the middle part of each second threaded rod is rotatably connected to the top of a first threaded cylinder; A support plate, which is horizontally arranged between a pair of second threaded rods, and the bottom of the support plate is connected to the bottom surface of the base through a vertically arranged second telescopic rod; A head fixing plate is slidably arranged on the top of the base along the length direction of the base and is located at one end of the first threaded rod. A head fixing piece is arranged on the head fixing plate.

2. The perfusion fixation device for animal experiments according to claim 1, characterized in that: A collar with an axis perpendicular to the axis of the first threaded rod is fixedly arranged on the top of each first threaded cylinder, and each second threaded rod is coaxially threadedly rotatably sleeved in the corresponding collar.

3. The perfusion fixation device for animal experiments according to claim 2, characterized in that: The support plate includes a first plate body and two second plate bodies respectively arranged on both sides of the first plate body, each second plate body is slidably connected to the first plate body along the length direction of the base, and the side of each second plate body is connected to the adjacent first threaded tube through an L-shaped first connecting rod, and the vertical part of the first connecting rod is a telescopic structure.

4. The perfusion fixation device for animal experiments according to claim 3, characterized in that: One side of the head fixing plate is connected to an adjacent first threaded cylinder through an L-shaped second connecting rod.

5. The perfusion fixation device for animal experiments according to claim 4, characterized in that: An inflatable air bag is provided on the upper surface of the first plate body and each second plate body.

6. The perfusion fixation device for animal experiments according to claim 5, characterized in that: Two bellows are provided on the movable sleeve of each second threaded rod, a bellows is correspondingly provided between a second threaded cylinder and the collar, and two ends of each bellows are respectively connected to the second threaded cylinder and the collar.

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