Oscillating device for cell culture and amplification
By designing a cell culture oscillation device including a base, a moving frame, a rotating cylinder and a driving rod, the problem of the existing device's low efficiency in fast clamping and oscillation is solved, and a more efficient cell test tube clamping and oscillation effect is achieved.
Patent Information
- Application Number
- CN202421163447.6
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-05-27
- Publication Date
- 2025-03-11
- Estimated Expiration
- 2034-05-27
AI Technical Summary
The existing shock device for cell culture and expansion is not convenient for fast clamping of cell test tubes in the same batch according to the size of the cell test tubes, and the staff's hand-cranking cell test tubes for oscillation is not efficient and has a high labor intensity.
An oscillation device including a base, a moving frame, a rotating cylinder and a driving rod is designed. The rotating cylinder and the cell test tube are driven to reciprocate the oscillation through the driving rod, and the automatic outward movement of the moving frame is realized through the elastic member, simplifying the clamping process.
The function of fast clamping according to the cell test tube size is realized, the fixing effect and oscillation efficiency of the device are improved, and labor intensity is reduced.
Smart Images

Figure CN222593885U_ABST
Abstract
Description
Technical Field
[0001] The utility model belongs to the technical field of cell culture equipment, and more specifically, particularly relates to an oscillating device for cell culture and amplification. Background Art
[0002] In the process of biological cell culture, precipitation is prone to occur if the sample is left standing for a long time, resulting in uneven reaction and affecting the culture effect of the biological cells. Therefore, it is necessary to shake the cell sample and oscillate the sample, which is a common experimental operation.
[0003] When using the existing similar shaking devices for cell culture and expansion, the devices are not convenient for quickly clamping the cell test tubes of the same batch according to the size of the cell test tubes, and the staff manually shakes the cell test tubes for shaking, which is inefficient and labor-intensive. Utility Model Content
[0004] In order to solve the above technical problems, the utility model provides an oscillating device for cell culture and expansion, so as to solve the problem that existing similar devices are not convenient for quickly clamping cell test tubes of the same batch according to the sizes of the cell test tubes, and the method of manually shaking the cell test tubes for oscillation by staff is inefficient and labor-intensive.
[0005] The utility model cell culture and expansion oscillating device is achieved by the following specific technical means:
[0006] A shaking device for cell culture and expansion, comprising a base and a moving frame;
[0007] The top of the movable frame is provided with a movable frame, and the movable frame is provided with a movable frame, and the movable frame is provided with a movable frame, and the movable frame is provided with a movable frame.
[0008] In at least some embodiments, a group of threaded rods are fixedly mounted on the rotating rod, a group of connecting plates are fixedly mounted on the outer side of the fixed elastic block, a group of threaded holes are opened on the connecting plates, and the threaded holes of the connecting plates on the outer side of the fixed elastic block are threadedly mounted on the threaded rods of the rotating rod.
[0009] In at least some embodiments, a group of guide grooves are formed on the top of the base, a group of guide blocks are formed on the bottom of the mounting seat, and the guide blocks formed on the bottom of the mounting seat are slidably mounted on the guide grooves formed on the top of the base.
[0010] In at least some embodiments, a group of first bevel gears are fixedly mounted on the outer end of the rotating rod, nine groups of second bevel gears are fixedly mounted on the driving rod, and the nine groups of second bevel gears on the driving rod are respectively meshed and transmission-connected with the first bevel gears at the outer end of the rotating rod.
[0011] In at least some embodiments, a set of drive shafts are fixedly mounted on the top of the drive disc, a set of drive grooves are opened on the outer end of the mounting seat, and the drive shafts on the top of the drive disc are slidably mounted in the drive grooves opened on the outer end of the mounting seat.
[0012] In at least some embodiments, a group of outer gear rings are fixedly mounted on the bottom of the rotating cylinder, a group of racks are fixedly mounted on the inner end of the fixed frame, and the outer gear rings at the bottom of the rotating cylinder are meshed and transmission-connected with the racks at the inner end of the fixed frame.
[0013] In at least some embodiments, a group of top blocks are fixedly installed on the top of the rotating cylinder, a group of inner slide grooves are opened at the bottom of the fixed elastic block, and the inner slide grooves opened at the bottom of the fixed elastic block are slidably installed on the top block at the top of the rotating cylinder.
[0014] Compared with the prior art, the utility model of a cell culture and expansion shaking device has the following beneficial effects:
[0015] 1. The arrangement of the driving rod and the fixed elastic block is conducive to placing the cell test tubes in the rotating cylinder respectively and moving the movable rack to the right, so that the nine groups of second bevel gears on the driving rod are respectively meshed and connected with the first bevel gear at the outer end of the rotating rod, and the inner slide groove opened at the bottom of the fixed elastic block is slidably installed on the top block at the top of the rotating cylinder, and the threaded hole of the outer connecting plate of the fixed elastic block is threadedly installed on the threaded rod of the rotating rod. The driving rod is rotated to drive the nine groups of rotating rods to rotate respectively, so that the fixed elastic block threadedly installed on the threaded rod moves inward, so that the device is convenient for quickly clamping the cell test tubes of the same batch according to the size of the cell test tubes, thereby improving the fixing effect of the device, and loosening the movable rack. Under the action of the elastic member on the slide rod, the movable rack automatically moves outward, and the second bevel gear on the driving rod is not meshed with the first bevel gear at the outer end of the rotating rod.
[0016] 2. The setting of the rotating cylinder is conducive to driving the drive disk to rotate through the motor, so as to drive the mounting seat and the cell test tubes in the rotating cylinder to reciprocate left and right, and the outer gear ring at the bottom of the rotating cylinder is meshed and connected with the rack at the inner end of the fixed frame. When the mounting seat moves in the middle section of the base, the rotating cylinder can be driven to rotate back and forth through the rack. The rotating shafts at the outer ends of the nine groups of rotating cylinders are rotatably installed in the rotating holes of the connecting rods. That is, while the cell test tubes in the nine groups of rotating cylinders are reciprocatingly oscillating left and right, they themselves reciprocate, which effectively improves the vibration effect of the device on cell culture and amplification in the cell test tubes. BRIEF DESCRIPTION OF THE DRAWINGS
[0017] Figure 1 It is a front axial view schematic diagram of the utility model.
[0018] Figure 2 It is a rear side shaft view schematic diagram of the utility model.
[0019] Figure 3 It is a schematic diagram of disassembly and assembly of the mounting seat of the utility model.
[0020] Figure 4 It is a schematic diagram of the installation of the mobile rack of the utility model.
[0021] Figure 5 It is a schematic diagram of the installation of the outer gear ring of the utility model.
[0022] Figure 6 It is a cross-sectional schematic diagram of the rotating drum of the utility model.
[0023] In the figure, the corresponding relationship between the component names and the figure numbers is as follows:
[0024] 1. Base; 101. Guide groove; 102. Drive disc; 1021. Drive shaft; 1022. Motor; 103. Fixed frame; 1031. Rack; 1032. Slide rod; 1033. Elastic member; 1034. Mobile frame; 104. Drive rod; 1041. Second bevel gear; 2. Mounting seat; 201. Drive groove; 202. Guide block; 203. Bracket; 2031. Fixed cylinder; 3. Rotating cylinder; 301. Support rod; 3011. Rotating shaft; 302. Fixed elastic block; 3021. Inner slide groove; 3022. Connecting plate; 303. Rotating rod; 3031. First bevel gear; 3032. Threaded rod; 304. Top block; 305. Outer gear ring; 306. Fixed elastic plate; 4. Connecting rod. DETAILED DESCRIPTION
[0025] The implementation of the utility model is further described in detail below in conjunction with the drawings and examples.
[0026] As attached Figure 1 As shown in the attached figure:
[0027] Embodiment 1: The utility model provides an oscillating device for cell culture and expansion, comprising a base 1 and a mobile frame 1034;
[0028] A set of drive disks 102 are rotatably mounted on the outer end of the base 1, a set of motors 1022 are fixedly mounted on the outer end of the base 1, a set of mounting seats 2 are slidably mounted on the top of the base 1, a set of fixed frames 103 are fixedly mounted on the rear end of the base 1, two sets of slide bars 1032 are fixedly mounted on the top of the fixed frames 103, two sets of elastic members 1033 are opened on the slide bars 1032, two sets of slide holes are opened on the bottom of the moving frame 1034, and the two sets of slide holes opened on the bottom of the moving frame 1034 are respectively slidably mounted on the slide bars 1032 on the top of the fixed frame 103, a set of drive rods 104 are rotatably mounted on the top of the moving frame 1034, and a set of brackets 203 are fixed on the top of the mounting seat 2 Nine groups of fixed cylinders 2031 are equidistantly fixedly installed on the top of the bracket 203, and a group of rotating cylinders 3 are rotatably installed in the fixed cylinders 2031 respectively. A group of support rods 301 are fixedly installed on the outer ends of the rotating cylinders 3, and a group of rotating shafts 3011 are fixed on the support rods 301. Nine groups of rotating holes are opened on the connecting rod 4, and the rotating shafts 3011 at the outer ends of the nine groups of rotating cylinders 3 are rotatably installed in the rotating holes of the connecting rod 4. A group of fixed elastic blocks 302 are threadedly installed on the top of the rotating cylinder 3, and a group of fixed elastic plates 306 are fixedly installed on the inner outer end of the rotating cylinder 3. A group of rotating rods 303 are also rotatably installed on the outer end of the rotating cylinder 3, and the rotating rods 303 are drivingly connected with the driving rod 104.
[0029] like Figures 4 to 6As shown, a group of top blocks 304 are fixedly installed on the top of the rotating cylinder 3, a group of inner slide grooves 3021 are opened at the bottom of the fixed elastic block 302, and the inner slide grooves 3021 opened at the bottom of the fixed elastic block 302 are slidably installed on the top block 304 on the top of the rotating cylinder 3, a group of first bevel gears 3031 are fixedly installed on the outer end of the rotating rod 303, and nine groups of second bevel gears 1041 are fixedly installed on the driving rod 104, and the nine groups of second bevel gears 1041 on the driving rod 104 are respectively connected to the outer ends of the rotating rod 303. The first bevel gear 3031 is meshed with the transmission connection, and a group of threaded rods 3032 are fixedly installed on the rotating rod 303, and a group of connecting plates 3022 are fixedly installed on the outer side of the fixed elastic block 302. A group of threaded holes are opened on the connecting plate 3022, and the threaded holes of the connecting plate 3022 on the outer side of the fixed elastic block 302 are threadedly installed on the threaded rod 3032 of the rotating rod 303; specifically, the two groups of sliding holes opened at the bottom of the mobile frame 1034 are respectively slidably installed on the sliding rod 1032 at the top of the fixed frame 103 , place the cell test tubes in the rotating cylinder 3 respectively, move the moving frame 1034 to the right, so that the nine groups of second bevel gears 1041 on the driving rod 104 are respectively meshed and connected with the first bevel gear 3031 at the outer end of the rotating rod 303, and the inner slide groove 3021 opened at the bottom of the fixed elastic block 302 is slidably installed on the top block 304 at the top of the rotating cylinder 3, and the threaded hole of the outer connecting plate 3022 of the fixed elastic block 302 is threadedly installed on the threaded rod 3032 of the rotating rod 303, and the driving rod 104 is rotated to drive The nine groups of rotating rods 303 are rotated respectively, so that the fixed elastic block 302 threadedly mounted on the threaded rod 3032 moves inward, so that the device can quickly clamp the cell test tubes of the same batch according to the size of the cell test tubes, thereby improving the fixing effect of the device, and loosening the movable frame 1034. Under the action of the elastic member 1033 on the sliding rod 1032, the movable frame 1034 automatically moves outward, and the second bevel gear 1041 on the driving rod 104 is not engaged with the first bevel gear 3031 at the outer end of the rotating rod 303.
[0030] Embodiment 2: Based on Embodiment 1, Figure 3 and Figure 5As shown, a group of outer gear rings 305 are fixedly installed at the bottom of the rotating cylinder 3, a group of racks 1031 are fixedly installed at the inner end of the fixed frame 103, and the outer gear ring 305 at the bottom of the rotating cylinder 3 is meshed and transmission-connected with the racks 1031 at the inner end of the fixed frame 103, a group of guide grooves 101 are opened at the top of the base 1, a group of guide blocks 202 are opened at the bottom of the mounting seat 2, and the guide blocks 202 opened at the bottom of the mounting seat 2 are slidably installed on the guide grooves 101 opened at the top of the base 1, a group of drive shafts 1021 are fixedly installed at the top of the drive disc 102, a group of drive grooves 201 are opened at the outer end of the mounting seat 2, and the drive shaft 1021 at the top of the drive disc 102 is slidably installed in the drive grooves 201 opened at the outer end of the mounting seat 2; specifically, the guide blocks 202 opened at the bottom of the mounting seat 2 are slidably installed on the bottom On the guide groove 101 opened on the top of the seat 1, the driving shaft 1021 on the top of the driving disc 102 is slidably installed in the driving groove 201 opened on the outer end of the mounting seat 2, and the motor 1022 drives the driving disc 102 to rotate, so as to drive the mounting seat 2 and the cell test tubes in the rotating cylinder 3 to reciprocate left and right, and the outer gear ring 305 at the bottom of the rotating cylinder 3 is meshed and connected with the rack 1031 at the inner end of the fixed frame 103. When the mounting seat 2 moves in the middle section of the base 1, the rotating cylinder 3 can be driven to rotate back and forth through the rack 1031. The rotating shafts 3011 at the outer ends of the nine groups of rotating cylinders 3 are rotatably installed in the rotating holes of the connecting rod 4, that is, while the cell test tubes in the nine groups of rotating cylinders 3 are reciprocatingly oscillating left and right, they themselves reciprocate, which effectively improves the vibration effect of the device on cell culture and amplification in the cell test tubes.
[0031] The specific usage and function of this embodiment are as follows:
[0032] When the utility model is in use, the cell test tubes are placed in the rotating cylinder 3 respectively, and the movable rack 1034 is moved to the right, so that the nine groups of second bevel gears 1041 on the driving rod 104 are respectively meshed and connected with the first bevel gear 3031 at the outer end of the rotating rod 303, and the driving rod 104 is rotated to drive the nine groups of rotating rods 303 to rotate respectively, so that the fixed elastic block 302 threadedly installed on the threaded rod 3032 moves inward, so that the device can quickly clamp the cell test tubes of the same batch according to the size of the cell test tubes, thereby improving the fixing effect of the device, and the movable rack 1034 is loosened, and under the action of the elastic member 1033 on the sliding rod 1032, the movable rack 103 4 automatically moves outward, and the second bevel gear 1041 on the driving rod 104 is not meshed with the first bevel gear 3031 at the outer end of the rotating rod 303; the motor 1022 drives the driving disc 102 to rotate, so as to drive the mounting seat 2 and the cell test tubes in the rotating cylinder 3 to reciprocate and oscillate left and right. When the mounting seat 2 moves in the middle section of the base 1, the rotating cylinder 3 can be driven to reciprocate through the rack 1031. The rotating shafts 3011 at the outer ends of the nine groups of rotating cylinders 3 are rotatably installed in the rotating holes of the connecting rod 4, that is, while the cell test tubes in the nine groups of rotating cylinders 3 reciprocate and oscillate left and right, they themselves reciprocate and rotate, which effectively improves the oscillation effect of the device on cell culture and amplification in the cell test tubes.
[0033] In this article, there are a few points to note:
[0034] 1. The drawings of the embodiments of the present disclosure only involve structures related to the embodiments of the present disclosure, and other structures may refer to general designs.
[0035] 2. In the absence of conflict, the embodiments of the present disclosure and the features therein may be combined with each other to obtain new embodiments.
[0036] The above are only specific embodiments of the present disclosure, but the protection scope of the present disclosure is not limited thereto. Any technician familiar with the technical field can easily think of changes or substitutions within the technical scope disclosed in the present disclosure, which should be included in the protection scope of the present disclosure. Therefore, the protection scope of the present disclosure should be based on the protection scope of the claims.
Claims
1. A shaking device for cell culture and expansion, comprising a base (1) and a movable frame (1034); A set of drive disks (102) are rotatably mounted on the outer end of the base (1), and are characterized in that: A motor (1022) is fixedly installed at the outer end of the base (1), a mounting seat (2) is slidably installed on the top of the base (1), a fixed frame (103) is fixedly installed at the rear end of the base (1), two sets of slide bars (1032) are fixedly installed on the top of the fixed frame (103), two sets of elastic members (1033) are opened on the slide bars (1032), two sets of slide holes are opened at the bottom of the movable frame (1034), and the two sets of slide holes opened at the bottom of the movable frame (1034) are respectively slidably installed on the slide bars (1032) at the top of the fixed frame (103), a driving rod (104) is rotatably installed on the top of the movable frame (1034), a bracket (203) is fixed on the top of the mounting seat (2), and the top of the bracket (203) Nine groups of fixed cylinders (2031) are equidistantly fixedly installed, and a group of rotating cylinders (3) are rotatably installed in the fixed cylinders (2031). A group of supporting rods (301) are fixedly installed on the outer ends of the rotating cylinders (3), and a group of rotating shafts (3011) are fixed on the supporting rods (301). Nine groups of rotating holes are opened on the connecting rod (4), and the rotating shafts (3011) at the outer ends of the nine groups of rotating cylinders (3) are rotatably installed in the rotating holes of the connecting rod (4). A group of fixed elastic blocks (302) are threadedly installed on the top of the rotating cylinder (3), and a group of fixed elastic plates (306) are fixedly installed on the inner outer end of the rotating cylinder (3). A group of rotating rods (303) are also rotatably installed on the outer ends of the rotating cylinders (3), and the rotating rods (303) are drivingly connected with the driving rod (104).
2. A cell culture and expansion oscillating device according to claim 1, characterized in that: A group of top blocks (304) are fixedly mounted on the top of the rotating cylinder (3), a group of inner slide grooves (3021) are opened at the bottom of the fixed elastic block (302), and the inner slide grooves (3021) opened at the bottom of the fixed elastic block (302) are slidably mounted on the top block (304) at the top of the rotating cylinder (3).
3. The cell culture and expansion oscillating device according to claim 1, characterized in that: A group of first bevel gears (3031) are fixedly mounted on the outer end of the rotating rod (303), nine groups of second bevel gears (1041) are fixedly mounted on the driving rod (104), and the nine groups of second bevel gears (1041) on the driving rod (104) are respectively meshed and transmission-connected with the first bevel gears (3031) at the outer end of the rotating rod (303).
4. The cell culture and expansion oscillating device according to claim 1, characterized in that: A group of threaded rods (3032) are also fixedly mounted on the rotating rod (303), and a group of connecting plates (3022) are fixedly mounted on the outer side of the fixed elastic block (302). A group of threaded holes are opened on the connecting plates (3022), and the threaded holes of the connecting plates (3022) on the outer side of the fixed elastic block (302) are threadedly mounted on the threaded rods (3032) of the rotating rod (303).
5. The cell culture and expansion oscillating device according to claim 1, characterized in that: A group of external toothed rings (305) are fixedly mounted on the bottom of the rotating cylinder (3), a group of racks (1031) are fixedly mounted on the inner end of the fixed frame (103), and the external toothed rings (305) at the bottom of the rotating cylinder (3) are meshed and transmission-connected with the racks (1031) at the inner end of the fixed frame (103).
6. The cell culture and expansion oscillating device according to claim 1, characterized in that: A group of guide grooves (101) are provided at the top of the base (1), a group of guide blocks (202) are provided at the bottom of the mounting seat (2), and the guide blocks (202) provided at the bottom of the mounting seat (2) are slidably mounted on the guide grooves (101) provided at the top of the base (1).
7. The oscillating device for cell culture and expansion according to claim 1, characterized in that: A group of drive shafts (1021) are fixedly mounted on the top of the drive disc (102), a group of drive grooves (201) are opened at the outer end of the mounting seat (2), and the drive shafts (1021) on the top of the drive disc (102) are slidably mounted in the drive grooves (201) opened at the outer end of the mounting seat (2).