Self-adaptive horizontal centrifugal mechanism

Abstract

The utility model discloses a self-adaptive horizontal centrifugal mechanism, and relates to the technical field of microplate centrifugal devices, through the arrangement of a connecting piece, when a rotating shaft accelerates and decelerates, a microplate can rotate in the acceleration and deceleration directions, so that the liquid level tends to be horizontal, the deviation amplitude of the liquid level is greatly reduced, and the centrifugal effect of the microplate is improved. Substances in the sample can be uniformly centrifuged to the bottom surface. And through the arrangement of the rotation amplitude limiting mechanism, the rotation amplitude of the microplate in the acceleration and deceleration directions is limited, and liquid level shaking caused by large-amplitude rotation of the microplate is avoided.

Description

Technical Field

[0001] The utility model relates to the technical field of microplate centrifugal devices, in particular to an adaptive horizontal centrifugal mechanism. Background Art

[0002] Microplate centrifuge is an important experimental equipment in the biological field, with a wide range of application scenarios. Microplate centrifuge is specially developed for microplates, which is convenient for separating droplets hanging on the wall, or centrifuging substances with higher density in the sample to the bottom of the plate. Currently, most microplate centrifuges on the market are shaftless or single-shaft designs. The shaftless design is placed vertically to directly centrifuge the microplate. The single-shaft design places the microplate horizontally or tilted during placement. Under the action of centrifugal force, the microplate is transformed into a stable vertical state, and substances with higher density in the liquid are centrifuged to the bottom.

[0003] However, the current patent only provides a rotating shaft or no rotating shaft in the direction of gravity, but no rotating shaft in the direction of acceleration. As a result, the liquid surface in the well plate will tilt in the direction of acceleration when accelerating or decelerating, and the liquid surface in the well cannot be parallel to the bottom. When the substance needs to be centrifuged to the bottom and tested, the use of a microplate centrifuge cannot evenly distribute the denser substances in the liquid at the bottom, which limits the use of the microplate centrifuge. Utility Model Content

[0004] In order to solve the technical problems existing in the background technology, the utility model proposes an adaptive horizontal centrifugal mechanism.

[0005] The utility model proposes an adaptive horizontal centrifugal mechanism, comprising a motor, a rotating shaft and a micro-porous plate, wherein the rotating shaft is installed at one end of the motor output shaft, connecting rods are installed on both sides of the rotating shaft, and a rotating member is installed at one end of the connecting rod away from the rotating shaft, a U-shaped frame is provided on the rotating member, and the U-shaped frame and the micro-porous plate are rotatably connected through a connecting member, and a rotation amplitude limiting mechanism is provided on the U-shaped frame, and the rotation amplitude limiting mechanism is used to limit the rotation amplitude of the micro-porous plate on the U-shaped frame.

[0006] Preferably, the rotating member comprises a U-shaped plate, a fixing rod is installed between the two sides of the inner wall of the U-shaped plate, a rotating rod is sleeved on the fixing rod, and the rotating rod and the fixing rod are rotatably connected at the penetration point, and one end of the rotating rod is installed on the U-shaped frame.

[0007] Preferably, two limiting rings are installed on the fixing rod, and the rotating rod is located between the two limiting rings.

[0008] Preferably, the connecting member includes a cross bar, and the cross bar is installed between the two sides of the inner wall of the U-shaped frame. Two V-shaped connecting rods are sleeved on the cross bar, and the penetration point between the V-shaped connecting rod and the cross bar is a rotational connection, and both ends of the V-shaped connecting rod are installed on the microporous plate.

[0009] Preferably, the rotation limiting mechanism comprises four telescopic rods, which are symmetrically distributed in pairs, one end of the telescopic rod is hinged to the U-shaped frame, and the other end of the telescopic rod is hinged to the microporous plate.

[0010] Preferably, the telescopic rod includes a cylinder, and a sliding rod is slidably connected inside the cylinder, a limit block is installed at one end of the sliding rod, one end of the cylinder is hinged to the U-shaped frame, the other end of the sliding rod extends to the outside of the cylinder, and the other end of the sliding rod is hinged to the microporous plate.

[0011] In the utility model, the proposed adaptive horizontal centrifugal mechanism has the following beneficial technical effects:

[0012] 1. Through the setting of the connecting piece, when the rotating shaft accelerates or decelerates, the microplate itself can rotate in the acceleration or deceleration direction, so that the liquid surface tends to be horizontal, which greatly reduces the amplitude of liquid surface deviation and is conducive to the uniform centrifugation of the substances in the sample to the bottom surface.

[0013] 2. By setting up a rotation amplitude limiting mechanism, the rotation amplitude of the microporous plate in the acceleration and deceleration directions is limited to avoid the shaking of the liquid surface caused by the large rotation of the microporous plate itself.

[0014] Additional aspects and advantages of the present invention will be given in part in the following description, and in part will become apparent from the following description, or will be learned through the practice of the present invention. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 It is the front view of the structure of the utility model;

[0016] Figure 2 This is a structural schematic diagram of the centrifugal rotation of the microplate after the rotating shaft rotates in the utility model;

[0017] Figure 3 It is a cross-sectional structural schematic diagram of the rotating part of the utility model;

[0018] Figure 4 It is a side view of the microporous plate, rotating part, connecting part and U-shaped frame of the utility model.

[0019] In the figure, 1, rotating shaft; 2, microporous plate; 3, connecting rod; 4, rotating member; 41, U-shaped plate; 42, fixed rod; 43, rotating rod; 44, limiting ring; 5, U-shaped frame; 6, connecting member; 61, cross bar; 62, V-shaped connecting rod; 7, rotation range limiting mechanism; 71, telescopic rod; 711, cylinder; 712, sliding rod; 713, limiting block; 8, motor. DETAILED DESCRIPTION

[0020] The embodiments of the present invention are described in detail below, and examples of the embodiments are shown in the accompanying drawings, wherein the same or similar symbols throughout represent the same or similar elements or elements with the same or similar functions. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain the present invention, and cannot be understood as limiting the present invention.

[0021] like Figure 1-Figure 4 An adaptive horizontal centrifuge mechanism shown includes a motor 8, a rotating shaft 1 and a microplate 2, wherein the rotating shaft 1 is installed at one end of the output shaft of the motor 8, and the rotation of the motor 8 drives the rotating shaft 1 to rotate. Connecting rods 3 are installed on both sides of the rotating shaft 1, and a rotating member 4 is installed at the end of the connecting rod 3 away from the rotating shaft 1. A U-shaped frame 5 is provided on the rotating member 4, and the U-shaped frame 5 and the microplate 2 are rotatably connected via a connecting member 6. A rotation amplitude limiting mechanism 7 is provided on the U-shaped frame 5, and the rotation amplitude limiting mechanism 7 is used to limit the rotation amplitude of the microplate 2 on the U-shaped frame 5.

[0022] A further improvement of the technical solution is that the rotating member 4 includes a U-shaped plate 41, a fixed rod 42 is installed between the two sides of the inner wall of the U-shaped plate 41, a rotating rod 43 is sleeved on the fixed rod 42, and the rotating rod 43 and the fixed rod 42 are rotatably connected at the penetration point, and one end of the rotating rod 43 is installed on the U-shaped frame 5.

[0023] A further improvement of the technical solution is that two limit rings 44 are installed on the fixed rod 42, and the rotating rod 43 is located between the two limit rings 44. The limit ring 44 is used to prevent the rotating rod 43 from sliding arbitrarily on the fixed rod 42, so that the rotation of the rotating rod 43 is more stable.

[0024] A further improvement of the technical solution is that the connecting member 6 includes a cross bar 61, and the cross bar 61 is installed between the two sides of the inner wall of the U-shaped frame 5, two V-shaped connecting rods 62 are sleeved on the cross bar 61, and the penetration point of the V-shaped connecting rod 62 and the cross bar 61 is a rotational connection, and both ends of the V-shaped connecting rod 62 are installed on the microporous plate 2.

[0025] A further improvement of the technical solution is that the connecting member 6 can be replaced by other existing rotating structures that can realize the rotational connection between the microporous plate 2 and the U-shaped frame 5.

[0026] A further improvement of the technical solution is that the rotation limiting mechanism 7 includes four telescopic rods 71, which are symmetrically distributed in pairs, one end of the telescopic rod 71 is hinged to the U-shaped frame 5, and the other end of the telescopic rod 71 is hinged to the microplate 2.

[0027] In an optional embodiment, the telescopic rod 71 includes a cylinder 711, and a slide rod 712 is slidably connected inside the cylinder 711. A limit block 713 is installed at one end of the slide rod 712. The limit block 713 is used to prevent the slide rod 712 from detaching from the cylinder 711. One end of the cylinder 711 is hinged to the U-shaped frame 5, and the other end of the slide rod 712 extends to the outside of the cylinder 711. The other end of the slide rod 712 is hinged to the microplate 2.

[0028] The rotation amplitude limiting mechanism 7 can be replaced by other existing limiting mechanisms that can limit the rotation amplitude of the microplate 2 on the U-shaped frame 5 .

[0029] By setting the connecting piece 6, when the rotating shaft 1 accelerates or decelerates, the microplate 2 itself can rotate in the acceleration or deceleration direction, so that the liquid surface tends to be horizontal, which greatly reduces the amplitude of liquid surface deviation and is conducive to uniform centrifugation of substances in the sample to the bottom surface.

[0030] The rotation amplitude limiting mechanism 7 is provided to limit the rotation amplitude of the microplate 2 in the acceleration and deceleration directions, thereby preventing the liquid surface from shaking due to the large rotation of the microplate 2 itself.

[0031] like Figure 1 As shown, the microplate 2 is in a horizontal state when it is stationary. Figure 2 As shown, at the beginning of centrifugation, as the centrifugal force increases, the angle between the bottom of the microplate 2 and the horizontal plane gradually increases from 0 degrees to 90 degrees. After the centrifugation starts, the microplate 2 gradually becomes vertical under the action of the centrifugal force.

[0032] After centrifugation, the substances with higher density in the solution can be spread more evenly on the bottom of the microplate 2 .

[0033] Specifically, when the rotating shaft 1 is accelerated in the clockwise direction driven by the motor 8, the microplate 2 is in the process of gradually becoming vertical. The liquid in the microplate 2 will deviate in the counterclockwise direction due to the accelerated rotation of the microplate 2. At this time, the microplate 2 itself can rotate, which is conducive to keeping the liquid level horizontal. When the liquid level is decelerated in the clockwise direction, it will deviate in the clockwise direction. At this time, the microplate 2 itself rotates and adjusts the angle in a direction that is conducive to keeping the liquid level horizontal, reducing the deviation of the sample during acceleration and deceleration, so that the sample liquid can maintain a certain uniform centrifugation to the bottom surface. The sample liquid is distributed in a certain uniform state at various positions on the horizontal plane.

[0034] During the process of increasing and decreasing the rotation speed of the rotating shaft 1, since the micro-plate 2 is connected without rigid restrictions, the micro-plate 2 adjusts its angle adaptively.

[0035] Meanwhile, the contents not described in detail in this specification belong to the prior art known to those skilled in the art.

[0036] It should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise", "axial", "radial", "circumferential" and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the referred device or element must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation on the present invention.

[0037] In addition, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" and "second" may explicitly or implicitly include at least one of the features. In the description of the present utility model, the meaning of "plurality" is at least two, such as two, three, etc., unless otherwise clearly and specifically defined.

[0038] In the present invention, unless otherwise clearly specified and limited, the terms "installed", "connected", "connected", "fixed" and the like should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral one; it can be a mechanical connection, an electrical connection, or communication with each other; it can be a direct connection, or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements, unless otherwise clearly defined. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0039] In the present utility model, unless otherwise clearly specified and limited, a first feature being "above" or "below" a second feature may mean that the first and second features are in direct contact, or the first and second features are in indirect contact through an intermediate medium. Moreover, a first feature being "above", "above" or "above" a second feature may mean that the first feature is directly above or obliquely above the second feature, or simply means that the first feature is higher in level than the second feature. A first feature being "below", "below" or "below" a second feature may mean that the first feature is directly below or obliquely below the second feature, or simply means that the first feature is lower in level than the second feature.

[0040] The above description is only a preferred specific implementation manner of the present invention, but the protection scope of the present invention is not limited thereto. Any technician familiar with the technical field can make equivalent replacements or changes within the technical scope disclosed by the present invention according to the technical scheme and the utility model concept of the present invention, which should be covered by the protection scope of the present invention.

Claims

1. An adaptive horizontal centrifugal mechanism, comprising a motor (8), a rotating shaft (1) and a microplate (2), wherein the rotating shaft (1) is mounted at one end of the output shaft of the motor (8), characterized in that: Connecting rods (3) are installed on both sides of the rotating shaft (1), and a rotating member (4) is installed on one end of the connecting rod (3) away from the rotating shaft (1). A U-shaped frame (5) is provided on the rotating member (4), and the U-shaped frame (5) and the microplate (2) are rotatably connected via a connecting member (6). A rotation amplitude limiting mechanism (7) is provided on the U-shaped frame (5), and the rotation amplitude limiting mechanism (7) is used to limit the rotation amplitude of the microplate (2) on the U-shaped frame (5).

2. The adaptive horizontal centrifugal mechanism according to claim 1, characterized in that: The rotating member (4) comprises a U-shaped plate (41), a fixed rod (42) is installed between the two sides of the inner wall of the U-shaped plate (41), a rotating rod (43) is sleeved on the fixed rod (42), and the rotating rod (43) and the fixed rod (42) are rotatably connected at the penetration point, and one end of the rotating rod (43) is installed on the U-shaped frame (5).

3. The adaptive horizontal centrifugal mechanism according to claim 2, characterized in that: Two limiting rings (44) are installed on the fixed rod (42), and the rotating rod (43) is located between the two limiting rings (44).

4. The adaptive horizontal centrifugal mechanism according to claim 1, characterized in that: The connecting member (6) comprises a cross bar (61), and the cross bar (61) is installed between the two sides of the inner wall of the U-shaped frame (5), two V-shaped connecting rods (62) are sleeved on the cross bar (61), and the V-shaped connecting rods (62) and the cross bar (61) are rotatably connected at the penetration point, and both ends of the V-shaped connecting rod (62) are installed on the microporous plate (2).

5. The adaptive horizontal centrifugal mechanism according to claim 1, characterized in that: The rotational amplitude limiting mechanism (7) comprises four telescopic rods (71), the four telescopic rods (71) are symmetrically distributed in pairs, one end of the telescopic rod (71) is hinged to the U-shaped frame (5), and the other end of the telescopic rod (71) is hinged to the microporous plate (2).

6. The adaptive horizontal centrifugal mechanism according to claim 5, characterized in that: The telescopic rod (71) comprises a cylinder (711), and a sliding rod (712) is slidably connected inside the cylinder (711), a limiting block (713) is installed at one end of the sliding rod (712), one end of the cylinder (711) is hinged to the U-shaped frame (5), the other end of the sliding rod (712) extends to the outside of the cylinder (711), and the other end of the sliding rod (712) is hinged to the microporous plate (2).

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