High-precision quantitative batching tank for attenuated live vaccine

Abstract

The utility model discloses a high-precision quantitative batching tank for attenuated live vaccines, which relates to the technical field of batching tanks for vaccines, and comprises an equipment body, a plurality of conveying tanks are uniformly arranged at the top of the equipment body, each conveying pipe is connected with an electromagnetic valve, a control unit is arranged in the equipment body, and the control unit is connected with the equipment body. Each electromagnetic valve is in communication connection with the control unit, the multiple batching tanks are arranged in the equipment body, the accurate liquid level of liquid in the batching tanks is monitored through the laser liquid level sensors, and the control unit regulates and controls the volume of raw materials output by the discharging tanks. The control unit can adjust the opening and closing time of the discharging tank and the electromagnetic valve in real time according to the measurement result of the laser liquid level sensor so as to supplement the lacked raw material capacity in the batching tank, or the control unit is used for controlling the liquid separator to absorb redundant liquid; the feedback control mechanism can ensure the batching accuracy and stability in the production process.

Description

Technical Field

[0001] The utility model relates to the technical field of vaccine batching tanks, in particular to a high-precision quantitative batching tank for attenuated live vaccines. Background Art

[0002] Attenuated live vaccines can stimulate the body to produce an immune response, improve the body's resistance to disease, and effectively prevent the occurrence of related diseases. The pathogens used in their preparation process are weakened so that they lose their pathogenicity but can still cause the immune system to produce an immune response.

[0003] The quantitative batching process of attenuated live vaccines is usually a key production step, which requires ensuring that each vaccine dose contains raw materials of appropriate concentration and volume. In the existing vaccine batching process, the prepared raw liquid is usually quantitatively delivered to the batching tank through a filling and batching machine. However, due to the low accuracy of the filling capacity, a capacity detection and compensation step is required afterwards. Utility Model Content

[0004] 1) Technical issues solved

[0005] The utility model provides a high-precision quantitative batching tank for attenuated live vaccines, so as to solve the problem of low precision of the existing filling and batching quantity.

[0006] 2) Technical solution

[0007] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a high-precision quantitative dosing tank for attenuated live vaccines, comprising an equipment body, a plurality of feed tanks are evenly arranged on the top of the equipment body, the liquid flow rate output by each feed tank is continuous and stable, and each feed pipe is connected to a solenoid valve, a control unit is arranged in the equipment body, each solenoid valve is communicatively connected to the control unit, and further comprising:

[0008] A batching tank, wherein a plurality of the batching tanks are arranged inside the equipment body, and each batching tank can rotate on a plane parallel to the horizontal plane; and

[0009] A laser liquid level sensor is slidably connected to the top of the equipment body and is perpendicular to the liquid surface in the batching tank. The laser liquid level sensor is communicatively connected to the control unit.

[0010] Furthermore, each of the feed tanks is connected to a discharge pipe, and a buffer tank is connected between the discharge pipe and the storage tank, and the solenoid valve is arranged at the discharge pipe port.

[0011] Furthermore, a slide rail is provided on the top of the equipment body, the laser liquid level sensor is slidably connected to the slide rail, and a first electric push rod parallel to the slide rail is provided on the slide rail, and the output end of the first electric push rod is fixedly connected to the laser liquid level sensor.

[0012] Furthermore, a rotating platform is provided inside the equipment body, each of the batching tanks is cylindrical, each of the batching tanks is evenly fixed on the rotating platform, and each of the batching tanks can be rotated to be directly below the discharge pipe and the laser liquid level sensor.

[0013] Furthermore, a second electric push rod perpendicular to the horizontal plane is arranged in the body of the equipment, a pipette is fixed to the output end of the second electric push rod, and the pipette can be vertically moved to the inside of each of the batching tanks.

[0014] Furthermore, a liquid dispenser is provided in the body of the device, the liquid dispenser is connected to the pipette, and the liquid dispenser is communicatively connected with the control unit, and the flow rate of the absorbed liquid of the liquid dispenser is continuous and stable.

[0015] 3) Beneficial effects:

[0016] Compared with the prior art, the utility model has the following beneficial effects:

[0017] The utility model monitors the accurate liquid level of the liquid in the batching tank through the laser liquid level sensor, and the control unit adjusts the raw material capacity output by the discharge tank. The control unit can adjust the opening and closing time of the discharge tank and the electromagnetic valve in real time according to the measurement result of the laser liquid level sensor to supplement the raw material capacity missing in the batching tank, or start the second electric push rod to move the pipette to below the liquid level of the batching tank, and the control unit controls the dispenser to absorb excess liquid. This feedback control mechanism can ensure the accuracy and stability of batching in the production process. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 It is a partial cross-sectional schematic diagram of the utility model;

[0019] Figure 2 It is a front cross-sectional view of the utility model;

[0020] Figure 3 It is a schematic diagram of the cross-sectional structure of the laser liquid level sensor and the feed tank in the utility model;

[0021] Figure 4 This is a schematic diagram of the laser liquid level sensor in the utility model measuring the volume of the solution in the batching tank;

[0022] Figure 5 It is a schematic diagram of the liquid pipette moving to the inside of the batching tank in the utility model;

[0023] Figure 6 This is a principle block diagram of the utility model;

[0024] In the figure: 1. Equipment body; 2. Bin door; 3. Rotating platform; 4. Feed tank; 5. Mixing tank; 6. Buffer tank; 7. Discharge pipe; 8. Solenoid valve; 9. Laser level sensor; 10. Slide rail; 11. Mounting frame; 12. First electric push rod; 13. Second electric push rod; 14. Dispenser; 15. Pipette. DETAILED DESCRIPTION

[0025] The technical solutions in the embodiments of the utility model will be clearly and completely described below in conjunction with the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, rather than all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the utility model.

[0026] In the description of the present invention, it should be understood that the terms "longitudinal", "lateral", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside" and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the referred device or element must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation on the present invention.

[0027] Combination Figures 1 to 6 The high-precision quantitative batching tank for attenuated live vaccines shown in the figure includes a device body 1, a plurality of feed tanks 4 are evenly arranged on the top of the device body 1, each feed tank 4 stores the raw materials for preparing the vaccine, and a metering pump or a peristaltic pump or other type of pump is installed in each feed tank 4 to ensure that the liquid is output at a quantitative flow rate. The function of these pumps is to make the output liquid flow rate of each feed tank 4 continuous and stable, and each feed pipe is connected to a solenoid valve 8, a control unit is arranged in the device body 1, and each solenoid valve 8 is connected to the control unit in communication, and the required precise batching is achieved by controlling the opening time of the solenoid valve 8.

[0028] In the above structure, the metering pump or peristaltic pump in each feed tank 4 will deliver the prepared raw materials to the solenoid valve 8 at a precise flow rate according to the set parameters. The opening time of the solenoid valve 8 is controlled by the control unit to ensure that the liquid flow output by each feed tank 4 remains stable. In this way, the precise batching required in the vaccine production process can be achieved.

[0029] More specifically, it also includes a batching tank 5. A rotating platform 3 is arranged inside the equipment body 1. Each batching tank 5 is cylindrical. The cylindrical batching tank 5 is convenient for calculating the liquid volume in the measuring tank, that is, the volume is equal to the bottom area multiplied by the height, so that it becomes more convenient and reliable to accurately measure and control the capacity of the liquid during the batching process. Each batching tank 5 is evenly fixed on the rotating platform 3, and it is ensured that each batching tank 5 can be rotated to the bottom of the discharge pipe 7. When batching is needed, the required batching tank 5 can be easily moved to the position of the discharge pipe 7 by rotating the rotating platform 3, thereby facilitating the liquid transportation and batching operations.

[0030] How to accurately determine the preparation volume of the raw materials in the batching tank 5, such as Figures 1 to 6 As shown, a laser liquid level sensor 9 is installed on the top of the equipment body 1, specifically Endress+Hauser Levelflex FMP55. This laser liquid level sensor 9 is suitable for measuring liquid levels in a sanitary environment, has high precision and reliability, and is suitable for liquid level monitoring of vaccine raw materials. The laser emitted by the laser liquid level sensor 9 is perpendicular to the liquid surface in the batching tank 5. After installation, the laser liquid level sensor 9 is calibrated to ensure that it accurately measures the liquid level height. Therefore, in some embodiments, the height of the batching tank 5 on the rotating platform 3 is determined. When the batching tank 5 rotates, the height distance L between the tank body and the laser liquid level sensor 9 remains unchanged, thereby ensuring that the sensor can accurately measure the liquid level height. The laser liquid level sensor 9 is communicatively connected to the control unit.

[0031] The volume of the liquid is calculated using the liquid level and the radius of the cylindrical container. The volume calculation formula is:

[0032] V=πr 2 h

[0033] Among them, r is the radius of the cylindrical batching tank 5, and h is the height of the liquid level in the batching tank 5.

[0034] Regarding the determination of h, the laser liquid level sensor 9 located directly above the batching tank 5 emits a short-pulse laser beam, which irradiates the liquid surface and is reflected. The sensor receives the laser signal reflected from the liquid surface, and measures the time interval from the emission to the reception of the laser, that is, the flight time of the laser. By knowing the propagation speed of the laser in the air (the speed of light), the sensor can calculate the distance X from the sensor to the liquid surface according to the flight time, that is, h=LX, thereby achieving high-precision liquid level measurement.

[0035] The measured liquid level height is converted into volume data, and the liquid volume is monitored and controlled in real time through the control unit to carry out the next batching work.

[0036] Regarding the raw material transportation of the feed tank 4, in some embodiments, each feed tank 4 is connected to a discharge pipe 7, and a buffer tank 6 is connected between the discharge pipe 7 and the storage tank. The buffer tank 6 plays a role in smoothing the flow of liquid. The buffer tank 6 can help reduce fluctuations and pressure changes during liquid flow to ensure stable liquid output. A solenoid valve 8 is installed at the mouth of the discharge pipe 7. When the solenoid valve 8 is opened, the liquid can flow out. When it is closed, the liquid stops flowing. The control unit controls the opening time and closing time of the solenoid valve 8 according to the set parameters, that is, by controlling the time difference between the opening and closing of the solenoid valve 8, the system can determine the volume of the output liquid, and the time difference multiplied by the flow rate can obtain the output volume. It should be noted that the solenoid valve 8 opens and closes quickly to ensure that the output volume is not affected.

[0037] In some embodiments, Figure 2 and Figure 3 As shown, a slide rail 10 is provided on the top of the equipment body 1, and the laser liquid level sensor 9 is fixed on the mounting frame 11, and is slidably connected to the slide rail 10 through the mounting frame 11, and a first electric push rod 12 parallel to the slide rail 10 is provided on the slide rail 10, and the output end of the first electric push rod 12 is fixedly connected to the mounting frame 11, and the mounting frame 11 is pushed by the first electric push rod 12, so that the laser liquid level sensor 9 moves on the same horizontal plane, thereby facilitating the measurement of the liquid volume in different ingredient tanks 5 at different positions.

[0038] In some embodiments, after the discharge tank outputs a certain amount of raw material volume into the batching tank 5, if the laser liquid level sensor 9 measures that the output raw material liquid volume is less than the set amount, the control unit can control the discharge tank to replenish the missing raw material according to the capacity measured by the laser liquid level sensor 9 and the set capacity. Specifically, the laser liquid level sensor 9 measures the output raw material liquid volume, determines the difference between the actual output and the set amount, and the control unit compares the actual output capacity with the set capacity to determine the missing raw material capacity. The control unit controls the discharge of the discharge tank and the opening time of the solenoid valve 8 according to the measured difference, and adds the missing raw material to the batching tank 5 again to supplement the insufficient output, monitors the amount of raw material added again, and ensures that the output capacity reaches the set requirements. According to the actual situation, it may be necessary to adjust the opening and closing time multiple times to achieve the accurate output capacity.

[0039] In some embodiments, Figure 5 to Figure 6As shown, a second electric push rod 13 perpendicular to the horizontal plane is provided in the equipment body 1, and a pipette 15 is fixed to the output end of the second electric push rod 13. The second electric push rod 13 enables the pipette 15 to move vertically to the inside of each batching tank 5. The pipette 15 is connected to the liquid separator 14, and the liquid separator 14 is communicated with the control unit. The flow rate of the absorbed liquid of the liquid separator 14 is continuous and stable. After the discharge tank outputs a certain amount of raw material volume into the batching tank 5, if the laser liquid level sensor 9 measures that the output raw material liquid volume is more than the set amount, the control unit controls the liquid separator 14 to work in the liquid suction.

[0040] Specifically, the laser liquid level sensor 9 detects the output raw material liquid volume. If it exceeds the set amount, the control unit controls the dispenser 14 to absorb excess raw material based on the comparison between the capacity measured by the laser liquid level sensor 9 and the set capacity. The second electric push rod 13 is started to move the pipette 15 vertically below the liquid level of the batching tank 5 to prepare to absorb excess liquid. The control unit communicates with the dispenser 14. Because the flow rate of liquid absorbed by the dispenser 14 is continuous and stable, the control unit controls the absorption time of the dispenser 14 to determine the flow rate of excess liquid absorbed, thereby ensuring that excess raw material is absorbed from the batching tank 5 and keeping the liquid capacity in the batching tank 5 within the set range.

[0041] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. The patent protection scope of the present invention shall be based on the claims. All equivalent structural changes made using the description and drawings of the present invention shall be included in the protection scope of the present invention.

Claims

1. A high-precision quantitative batching tank for attenuated live vaccines, comprising a device body (1), wherein a plurality of feed tanks (4) are evenly arranged on the top of the device body (1), characterized in that: The liquid flow rate output by each of the feed tanks (4) is continuous and stable, and each feed pipe is connected to a solenoid valve (8). A control unit is provided in the device body (1), and each of the solenoid valves (8) is communicatively connected to the control unit. The device also includes: A batching tank (5), wherein a plurality of the batching tanks (5) are arranged inside the equipment body (1), and each batching tank (5) can rotate on a plane parallel to a horizontal plane; and A laser liquid level sensor (9) is slidably connected to the top of the equipment body (1) and is perpendicular to the liquid surface in the batching tank (5). The laser liquid level sensor (9) is communicatively connected to the control unit.

2. The high-precision quantitative batching tank for attenuated live vaccines according to claim 1, characterized in that: Each of the feed tanks (4) is connected to a discharge pipe (7), and a buffer tank (6) is connected between the discharge pipe (7) and the storage tank, and the solenoid valve (8) is arranged at the outlet of the discharge pipe (7).

3. The high-precision quantitative batching tank for attenuated live vaccines according to claim 2, characterized in that: A slide rail (10) is arranged on the top of the equipment body (1), the laser liquid level sensor (9) is slidably connected to the slide rail (10), and a first electric push rod (12) parallel to the slide rail (10) is arranged on the slide rail (10), and the output end of the first electric push rod (12) is fixedly connected to the laser liquid level sensor (9).

4. The high-precision quantitative batching tank for attenuated live vaccines according to claim 3, characterized in that: A rotating platform (3) is arranged inside the equipment body (1); each of the batching tanks (5) is cylindrical; each of the batching tanks (5) is evenly fixed on the rotating platform (3); and each of the batching tanks (5) can be rotated to be directly below the discharge pipe (7) and the laser liquid level sensor (9).

5. The high-precision quantitative batching tank for attenuated live vaccines according to claim 4, characterized in that: A second electric push rod (13) perpendicular to the horizontal plane is arranged in the equipment body (1), a liquid pipette (15) is fixed to the output end of the second electric push rod (13), and the liquid pipette (15) can be vertically moved to the inside of each of the batching tanks (5).

6. The high-precision quantitative batching tank for attenuated live vaccines according to claim 5, characterized in that: A liquid dispenser (14) is arranged in the device body (1), the liquid dispenser (14) is connected to the liquid suction tube (15), and the liquid dispenser (14) is communicatively connected with the control unit, and the flow rate of liquid absorbed by the liquid dispenser (14) is continuous and stable.

Images