Liquid absorption amount measuring device and sample analyzer
By designing a liquid absorption measurement device including a sampling mechanism and a measuring mechanism, the problem that the liquid absorption volume of the sampling needle in the sample analyzer cannot be accurately measured, and more accurate sample analysis results are achieved.
Patent Information
- Application Number
- CN202420578071.9
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-03-22
- Publication Date
- 2025-03-25
- Estimated Expiration
- 2034-03-22
AI Technical Summary
In existing sample analyzers, the amount of liquid absorbed by the sampling needle cannot be accurately measured, resulting in errors in the test results.
A liquid absorbing amount measuring device is designed, including a sampling mechanism and a measuring mechanism. The sampling mechanism consists of a sampling needle, a pipeline assembly and a power assembly. The power assembly drives the sampling needle to absorb the liquid to be tested and transfers it to the measuring container. The measuring mechanism consists of a measuring container and a measuring sensor, which is used to measure the amount of liquid to be measured.
Through this device, the liquid absorbing volume of the sampling needle can be accurately measured, the error of the test result can be reduced, and the accuracy of sample analysis can be improved.
Smart Images

Figure CN222671834U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of calibration, in particular to a liquid absorption amount measuring device and a sample analyzer. Background Art
[0002] The sampling needle of the sample analyzer is designed to penetrate the rubber cover of the sample tube and extract a certain amount of sample. The amount of sample extracted by the sampling needle depends on the preset sampling needle aspiration time and the negative pressure of the gas circuit connected to the puncture needle. In order to ensure that the actual aspiration amount is basically consistent with the set quantitative amount, the sampling needle aspiration time and gas circuit negative pressure must be determined through precise calculations and long-term testing.
[0003] However, as the sampling needle is used and replaced, the air tightness and pressure inside it will change; and as the motor ages, the set aspiration time may also change. These will affect the accuracy of the aspiration volume, which may lead to errors in the test results. Therefore, it is particularly important to regularly calibrate the aspiration volume of the sampling needle to eliminate the possibility that the error in the sample aspiration volume will lead to inaccurate results of cell analysis. Utility Model Content
[0004] Based on this, it is necessary to provide a liquid aspirating volume measuring device and a sample analyzer to solve the problem that the liquid aspirating volume of the sampling needle cannot be accurately measured.
[0005] A liquid absorption amount measuring device, the liquid absorption amount measuring device comprising:
[0006] The sampling mechanism comprises a sampling needle, a pipeline assembly connected to the sampling needle, and a power assembly connected to the pipeline assembly;
[0007] A measuring mechanism, including a measuring container and a measuring sensor;
[0008] The power assembly is used to drive the sampling needle to absorb the test liquid through the pipeline assembly and transfer the test liquid to the measuring container, and the measuring sensor is used to measure the amount of the test liquid absorbed in the measuring container.
[0009] In one embodiment, the liquid absorption amount measuring device further includes a first switching member and a second switching member, and the pipeline assembly includes a first pipeline, a second pipeline and a third pipeline;
[0010] The first end of the first pipeline is connected to the sampling needle, and the second end of the first pipeline is connected to the measuring mechanism;
[0011] The first end of the second pipeline is connected to the measuring mechanism, and the second end of the second pipeline is connected to the power assembly;
[0012] The first end of the third pipeline is connected to the first end of the first pipeline, and the second end of the third pipeline is connected to the second end of the second pipeline;
[0013] The first switching element is disposed on the first pipeline or the second pipeline, and is used to connect or disconnect the first pipeline or the second pipeline;
[0014] The second switching element is disposed on the third pipeline, and is used to connect or disconnect the third pipeline.
[0015] In one embodiment, the liquid absorption amount measuring device further includes a third switching member, and the pipeline assembly includes a fourth pipeline, a fifth pipeline and a sixth pipeline;
[0016] The third switching element is connected to the sampling needle, the first end of the fourth pipeline, and the first end of the sixth pipeline, and is used to achieve connection or disconnection between the fourth pipeline and the sixth pipeline;
[0017] The second end of the fourth pipeline is connected to the measuring mechanism;
[0018] The first end of the fifth pipeline is connected to the measuring mechanism, and the second end of the fifth pipeline is connected to the power assembly;
[0019] The second end of the sixth pipeline is connected to the second end of the fifth pipeline.
[0020] In one embodiment, the power assembly includes a stroke driver and a power pump, the power pump is connected to the pipeline assembly, and is used to drive the sampling needle to absorb the liquid to be tested through the pipeline assembly; the stroke driver is used to drive the sampling needle to transfer to the opening of the measuring container, and the power pump is also used to drive the sampling needle to discharge the liquid to be tested through the pipeline assembly.
[0021] In one embodiment, the measuring sensor includes a gravity sensor, which is used to measure the initial weight of the measuring container when the test liquid is not contained in it, and the current weight of the measuring container after the test liquid is contained in it, so as to obtain the unit liquid absorption amount of the sampling for the test liquid.
[0022] In one embodiment, the calculation formula of the unit liquid absorption capacity is:
[0023] V=(m2-m1) / (ρ* / n)
[0024] In the above formula, V indicates the unit liquid aspiration volume; m1 indicates the initial weight; m2 indicates the current weight; ρ indicates the density of the sample; and n indicates the preset number of times the sampling needle aspirates the liquid to be tested.
[0025] In one of the embodiments, after completing the current measurement of the amount of the liquid to be tested, the power assembly is also used to drive the sampling needle to absorb the cleaning liquid through the pipeline assembly, and transfer the cleaning liquid to the measuring container for cleaning and to discharge the waste liquid generated by cleaning, and the gravity sensor is also used to measure the cleaning weight of the measuring container after cleaning.
[0026] In one of the embodiments, the measuring sensor is a pressure sensor, and the pressure sensor is used to measure the pressure of the liquid in the measuring container to obtain the liquid absorption amount of the liquid to be measured.
[0027] In one of the embodiments, the measuring sensor is a liquid level sensor, and the liquid level sensor is used to measure the liquid level height of the liquid to be tested in the measuring container to obtain the liquid absorption amount of the liquid to be tested.
[0028] A sample analyzer includes a detection device and the above-mentioned liquid absorption volume measuring device, wherein the power component is also used to drive the sampling needle to absorb the liquid to be tested through the pipeline component and transfer the liquid to be tested to the detection device, and the detection device is used to detect and analyze the liquid to be tested.
[0029] The utility model provides a device for measuring the amount of liquid aspirated, which comprises a sampling mechanism and a measuring mechanism, wherein the sampling mechanism comprises a sampling needle, a pipeline assembly connected to the sampling needle, and a power assembly connected to the pipeline assembly; the measuring mechanism comprises a measuring container and a measuring sensor; wherein the power assembly is used to drive the sampling needle to absorb a liquid to be tested through the pipeline assembly and transfer the liquid to be tested to the measuring container, and the measuring sensor is used to measure the amount of liquid aspirated of the liquid to be tested contained in the measuring container, thereby obtaining the amount of liquid aspirated by the sampling needle. BRIEF DESCRIPTION OF THE DRAWINGS
[0030] In order to more clearly illustrate the embodiments of the utility model or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.
[0031] in:
[0032] Figure 1 It is a structural schematic diagram of the liquid absorption amount measuring device in the first embodiment;
[0033] Figure 2 It is a structural schematic diagram of the liquid absorption amount measuring device in the second embodiment;
[0034] Figure 3It is a structural schematic diagram of the liquid absorption amount measuring device in the third embodiment;
[0035] Figure 4 It is a structural schematic diagram of the liquid absorption amount measuring device in the fourth embodiment;
[0036] Figure 5 is a schematic diagram of the structure of a sample analyzer;
[0037] Figure numerals: sample analyzer 001, liquid aspiration measurement device 100, sampling mechanism 110, sampling needle 111, pipeline assembly 112, first pipeline 112a, second pipeline 112b, third pipeline 112c, fourth pipeline 112d, fifth pipeline 112e, sixth pipeline 112f, power assembly 113, stroke driver 113a, power pump 113b, measuring mechanism 120, measuring container 121, measuring sensor 122, first switching element 131, second switching element 132, third switching element 133, detection device 200. DETAILED DESCRIPTION
[0038] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments of the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.
[0039] The terms "first", "second", etc. in the specification and claims of this application and the above-mentioned drawings are used to distinguish different objects, rather than to describe a specific order. In addition, the terms "including" and "having" and any variations thereof are intended to cover non-exclusive inclusions. For example, a process, device, system, product or equipment that includes a series of steps or units is not limited to the listed steps or units, but optionally includes steps or units that are not listed, or optionally includes other steps or units inherent to these processes, devices, products or equipment.
[0040] Reference to "embodiments" herein means that a particular feature, structure, or characteristic described in conjunction with the embodiments may be included in at least one embodiment of the present application. The appearance of the phrase in various locations in the specification does not necessarily refer to the same embodiment, nor is it an independent or alternative embodiment that is mutually exclusive with other embodiments. It is explicitly and implicitly understood by those skilled in the art that the embodiments described herein may be combined with other embodiments.
[0041] like Figure 1 As shown, Figure 1is a schematic structural diagram of the liquid absorption amount measuring device 100 in the first embodiment. In this embodiment, the liquid absorption amount measuring device 100 includes a sampling mechanism 110 and a measuring mechanism 120 .
[0042] Specifically, the sampling mechanism 110 includes a sampling needle 111 , a pipeline assembly 112 connected to the sampling needle 111 , and a power assembly 113 connected to the pipeline assembly 112 ; the measuring mechanism 120 includes a measuring container 121 and a measuring sensor 122 .
[0043] The pipeline assembly 112 is a pipeline system connecting the sampling needle 111 and the power assembly 113, which may include valves, pipelines and other related components. The power assembly 113 is used to provide suction force for sucking the liquid to be tested and driving force for moving the liquid to be tested. In this embodiment, it is specifically used to drive the sampling needle 111 to suck the liquid to be tested through the pipeline assembly 112 and transfer the liquid to be tested to the measuring container 121. The measuring container 121 is a container for containing a sample of the liquid to be tested, and the measuring sensor 122 is used to measure the amount of liquid to be tested contained in the measuring container 121, thereby obtaining the amount of liquid sucked by the sampling needle.
[0044] like Figure 2 As shown, Figure 2 1 is a schematic diagram of the structure of the liquid absorption amount measuring device 100 in the second embodiment. In this embodiment, the liquid absorption amount measuring device 100 also includes a first switching member 131 and a second switching member 132, which can be a two-way electromagnetic valve or a pinch valve, and can switch the switch state of the connecting pipeline. The pipeline assembly includes a first pipeline 112a, a second pipeline 112b and a third pipeline 112c, which constitute the flow path of the liquid during the absorption and normal measurement process.
[0045] Specifically, the first end of the first pipeline 112a is connected to the sampling needle 111, and the second end of the first pipeline 112a is connected to the measuring mechanism 120; the first end of the second pipeline 112b is connected to the measuring mechanism 120, and the second end of the second pipeline 112b is connected to the power assembly 113; the first end of the third pipeline 112c is connected to the first end of the first pipeline 112a, and the second end of the third pipeline 112c is connected to the second end of the second pipeline 112b.
[0046] The first switching element 131 is disposed on the first pipeline 112a or the second pipeline 112b to connect or disconnect the first pipeline 112a or the second pipeline 112b; the second switching element 132 is disposed on the third pipeline 112c to connect or disconnect the third pipeline 112c.
[0047] When liquid measurement is required, the first switching element 131 is opened and the second switching element 132 is closed. This arrangement provides suction force with the power assembly 113, which can ensure that the liquid to be tested flows from the sampling needle 111 through the first pipeline 112a into the measuring container 121 for liquid aspiration measurement, and then flows out from the second pipeline 112b after measurement. When the aspiration operation is performed normally, the first switching element 131 is closed and the second switching element 132 is opened, which can ensure that the liquid to be tested flows directly from the sampling needle 111 through the third pipeline 112c to avoid interference with the measuring container 121. It can be seen that this embodiment can switch between the measurement and normal aspiration functions on the premise of correctly switching the switch states of the first switching element 131 and the second switching element 132 to meet different operational requirements.
[0048] like Figure 3 As shown, Figure 3 1 is a schematic diagram of the structure of the liquid absorption amount measuring device 100 in the third embodiment. In this embodiment, the liquid absorption amount measuring device 100 also includes a third switching member 133, which can be a three-way electromagnetic valve or a mechanical valve, and can switch the switch state of the connecting pipeline. The pipeline assembly includes a fourth pipeline 112d, a fifth pipeline 112e and a sixth pipeline 112f, which also constitute the flow path of the liquid during the absorption and normal measurement process.
[0049] Specifically, the third switching member 133 is connected to the sampling needle 111, the first end of the fourth pipeline 112d, and the first end of the sixth pipeline 112f, so as to realize the connection or disconnection between the fourth pipeline 112d and the sixth pipeline 112f; the second end of the fourth pipeline 112d is connected to the measuring mechanism 120; the first end of the fifth pipeline 112e is connected to the measuring mechanism 120, and the second end of the fifth pipeline 112e is connected to the power assembly 113; the second end of the sixth pipeline 112f is connected to the second end of the fifth pipeline 112e.
[0050] Similarly, when liquid measurement is required, the third switching element 133 controls the sampling needle 111 to be connected to the fourth pipeline 112d, and the passage between the sampling needle 111 and the sixth pipeline 112f is cut off. In this way, the power component 113 provides suction force, which can ensure that the liquid to be tested flows from the sampling needle 111 through the fourth pipeline 112d into the measuring container 121 for liquid aspiration measurement, and then flows out from the fifth pipeline 112e after measurement. When the aspiration operation is performed normally, the third switching element 133 controls the passage between the sampling needle 111 and the fourth pipeline 112d to be cut off, and the sampling needle 111 is connected to the sixth pipeline 112f, which can ensure that the liquid to be tested flows directly from the sampling needle 111 through the sixth pipeline 112f to avoid interference from the measuring mechanism 120. It can be seen that, under the premise of correctly switching the switch state of the third switching element 133, the present embodiment can switch between the measurement and normal aspiration functions to meet different operation requirements.
[0051] like Figure 4 As shown, Figure 4 This is a structural schematic diagram of the liquid aspiration volume measuring device 100 in the fourth embodiment. In this embodiment, the power component 113 includes a stroke driver 113a and a power pump 113b. The power pump 113b is connected to the pipeline component 112, and is used to drive the sampling needle 111 to absorb the liquid to be tested through the pipeline component 112; the stroke driver 113a is used to drive the sampling needle 111 to transfer to the opening of the measuring container 121, and the power pump 113b is also used to drive the sampling needle 111 to discharge the liquid to be tested through the pipeline component 112.
[0052] Specifically, at position A, the power pump 113b extracts a sample from the liquid to be tested through the pipeline assembly 112 and introduces the liquid into the pipeline assembly 112. The sampling needle 111 is controlled by the stroke driver 113a and is moved to position B at the opening of the measuring container 121. At position B, the power pump 113b acts on the sampling needle 111 again through the pipeline assembly 112, but this time the function is to discharge the liquid to be tested in the sampling needle 111 and discharge it into the measuring container 121 through the pipeline assembly 112. With this design, the device can complete the operation from extracting the liquid to be tested to discharging it.
[0053] In a specific embodiment, the measuring sensor 122 includes a gravity sensor, which is used to measure the initial weight of the measuring container 121 when there is no test liquid, and the current weight of the measuring container 121 after the test liquid is contained, so as to obtain the unit liquid aspirated by the sampling needle 111 for the test liquid.
[0054] Furthermore, the calculation formula of unit liquid absorption is:
[0055] V=(m2-m1) / (ρ* / n)
[0056] In the above formula, V indicates the unit liquid aspirating volume; m1 indicates the initial weight; m2 indicates the current weight; ρ indicates the density of the sample; and n indicates the preset number of times the sampling needle 111 aspirates the liquid to be tested.
[0057] The purpose of this formula is to calculate the unit amount of liquid aspirated by measuring the initial and current weights, which are divided by the density and the number of sampling times. This design makes it possible to more accurately quantify the amount of liquid aspirated each time, which is helpful for liquid measurement and analysis in experiments or industrial processes.
[0058] Furthermore, after completing the current measurement of the liquid volume to be measured, the power component 113 is also used to drive the sampling needle 111 through the pipeline component 112 to absorb the cleaning liquid, and transfer the cleaning liquid to the measuring container 121 for cleaning and to discharge the waste liquid generated by cleaning. The gravity sensor is also used to measure the cleaning weight of the measuring container 121 after cleaning.
[0059] The cleaning fluid is used to clean any residual sample in the measuring container 121. This helps to avoid cross contamination between samples and ensure the accuracy of subsequent sampling. The cleaning weight is the net weight of the measuring container 121 after cleaning. By comparing the cleaning weight and the initial weight, it can be ensured that no residue is left in the sample container, thereby maintaining the accuracy and reliability of the next sampling.
[0060] In a specific embodiment, the measuring sensor 122 is a pressure sensor, which is used to measure the liquid pressure in the measuring container 121 to obtain the amount of liquid absorbed by the liquid to be measured. Specifically, the pressure sensor can sense the pressure exerted by the liquid on the container wall, and based on the pressure, the amount of liquid absorbed by the liquid to be measured can be calculated by corresponding physical formulas using known parameters such as liquid density and gravity.
[0061] In a specific embodiment, the measuring sensor 122 is a liquid level sensor, which is used to measure the liquid level height of the liquid to be measured in the measuring container 121 to obtain the liquid absorption amount of the liquid to be measured. Specifically, the liquid level sensor can usually detect the position of the liquid surface to determine the liquid level height. Based on the liquid level height, the known container shape and cross-sectional area can be used to calculate the liquid absorption amount of the liquid to be measured through simple geometric calculations or calibration data provided by the liquid level sensor.
[0062] The present invention also provides a sample analyzer 001, such as Figure 5 As shown, the sample analyzer 001 includes a detection device 200 and a liquid aspiration measurement device 100. The power component 113 is also used to drive the sampling needle 111 to absorb the test liquid through the pipeline component 112, and transfer the test liquid to the detection device 200. The detection device 200 is used to detect and analyze the test liquid. Among them, the detection device 200 may include sensors, optical devices, electronic components or other technical equipment suitable for detection and analysis. Its function is to obtain data on the properties, components or other relevant information of the test liquid.
[0063] The technical features of the above embodiments may be combined arbitrarily. To make the description concise, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.
[0064] The above embodiments only express several implementation methods of the present application, and the descriptions thereof are relatively specific and detailed, but they cannot be understood as limiting the scope of the present application. It should be pointed out that, for a person of ordinary skill in the art, several modifications and improvements can be made without departing from the concept of the present application, and these all belong to the protection scope of the present application. Therefore, the protection scope of the present application shall be subject to the attached claims.
Claims
1. A liquid absorption measurement device, characterized in that: The liquid absorption measuring device comprises: The sampling mechanism comprises a sampling needle, a pipeline assembly connected to the sampling needle, and a power assembly connected to the pipeline assembly; A measuring mechanism, including a measuring container and a measuring sensor; The power assembly is used to drive the sampling needle to absorb the test liquid through the pipeline assembly and transfer the test liquid to the measuring container, and the measuring sensor is used to measure the amount of the test liquid absorbed in the measuring container.
2. The liquid absorption amount measuring device according to claim 1, characterized in that: The liquid absorption amount measuring device further comprises a first switching member and a second switching member, and the pipeline assembly comprises a first pipeline, a second pipeline and a third pipeline; The first end of the first pipeline is connected to the sampling needle, and the second end of the first pipeline is connected to the measuring mechanism; The first end of the second pipeline is connected to the measuring mechanism, and the second end of the second pipeline is connected to the power assembly; The first end of the third pipeline is connected to the first end of the first pipeline, and the second end of the third pipeline is connected to the second end of the second pipeline; The first switching element is disposed on the first pipeline or the second pipeline, and is used to connect or disconnect the first pipeline or the second pipeline; The second switching element is disposed on the third pipeline, and is used to connect or disconnect the third pipeline.
3. The liquid absorption amount measuring device according to claim 1, characterized in that: The liquid absorption amount measuring device further comprises a third switching member, and the pipeline assembly comprises a fourth pipeline, a fifth pipeline and a sixth pipeline; The third switching element is connected to the sampling needle, the first end of the fourth pipeline, and the first end of the sixth pipeline, and is used to achieve connection or disconnection between the fourth pipeline and the sixth pipeline; The second end of the fourth pipeline is connected to the measuring mechanism; The first end of the fifth pipeline is connected to the measuring mechanism, and the second end of the fifth pipeline is connected to the power assembly; The second end of the sixth pipeline is connected to the second end of the fifth pipeline.
4. The liquid absorption measuring device according to claim 1, characterized in that: The power assembly includes a stroke driver and a power pump. The power pump is connected to the pipeline assembly and is used to drive the sampling needle to absorb the liquid to be tested through the pipeline assembly. The stroke driver is used to drive the sampling needle to transfer to the opening of the measuring container, and the power pump is also used to drive the sampling needle to discharge the liquid to be tested through the pipeline assembly.
5. The liquid absorption amount measuring device according to claim 1, characterized in that: The measuring sensor comprises a gravity sensor, which is used to measure the initial weight of the measuring container when the liquid to be tested is not contained in the measuring container, and the current weight of the measuring container after the liquid to be tested is contained in the measuring container, so as to obtain the unit liquid absorption amount of the sampling for the liquid to be tested.
6. The liquid absorption amount measuring device according to claim 5, characterized in that: The calculation formula of the unit liquid absorption is: V=(m2-m1) / (ρ* / n) In the above formula, V indicates the unit liquid aspiration volume; m1 indicates the initial weight; m2 indicates the current weight; ρ indicates the density of the sample; and n indicates the preset number of times the sampling needle aspirates the liquid to be tested.
7. The liquid absorption amount measuring device according to claim 5, characterized in that: After completing the current measurement of the liquid volume to be tested, the power assembly is also used to drive the sampling needle to absorb the cleaning liquid through the pipeline assembly, and transfer the cleaning liquid to the measuring container for cleaning and discharge the waste liquid generated by cleaning. The gravity sensor is also used to measure the cleaning weight of the measuring container after cleaning.
8. The liquid absorption amount measuring device according to claim 1, characterized in that: The measuring sensor is a pressure sensor, and the pressure sensor is used to measure the liquid pressure in the measuring container to obtain the liquid absorption amount of the liquid to be measured.
9. The liquid absorption amount measuring device according to claim 1, characterized in that: The measuring sensor is a liquid level sensor, and the liquid level sensor is used to measure the liquid level height of the liquid to be measured in the measuring container to obtain the liquid absorption amount of the liquid to be measured.
10. A sample analyzer, characterized in that: It comprises a detection device and a liquid aspiration measuring device as described in any one of claims 1 to 9, wherein the power component is also used to drive the sampling needle to absorb the liquid to be tested through the pipeline component and transfer the liquid to be tested to the detection device, and the detection device is used to detect and analyze the liquid to be tested.