Magnetic frame

Abstract

The utility model discloses a magnetic frame which comprises a base plate, a first assembly and a second assembly, the first assembly and the second assembly are both connected with the base plate, the first assembly is rotatably connected with the base plate with the joint of the first assembly and the base plate as the axis, and the second assembly is rotatably connected with the base plate with the joint of the second assembly and the base plate as the axis. A containing unit used for containing the magnetic assembly is further arranged between the first assembly and the second assembly. And through holes for storing centrifugal tubes are formed in the first assembly and the second assembly. According to the magnetic frame provided by the invention, the first component and the second component can be rotationally connected with each other by taking the joint of the first component and the base plate as the axis, and the centrifugal tubes can be stored on the first component and the second component, so that when liquid in the centrifugal tubes on the first component or the second component needs to be poured, the liquid can be poured out; the liquid in the centrifugal tube can be poured out only by rotating the first assembly or the second assembly, and the accommodating unit for accommodating the magnetic assembly is also arranged between the first assembly and the second assembly, so that the magnetic beads in the centrifugal tube cannot be poured out in the pouring process.

Description

Technical Field

[0001] The present application relates to the technical field of biological separation devices, and in particular to a magnetic frame for magnetic bead purification. Background Art

[0002] With the popularization of testing and treatment methods such as genetic testing, personalized drug delivery, and prenatal diagnosis, as well as the realization of automation in the biological field, magnetic separation technology represented by the biomagnetic bead method has been widely used in the fields of cell separation, protein purification, immunology, and microbiology testing. Magnetic separation technology uses superparamagnetic magnetic beads to separate biomacromolecules in liquid phase, and has been widely used in the biomedical field. Compared with traditional separation methods such as extraction, precipitation, and centrifugation, it can quickly separate nucleic acids, proteins, etc. from other substances in cells. It has the characteristics of automation, simple operation, and short time. The magnetic stand is a commonly used magnetic separation device in the laboratory. In magnetic separation technology, it serves as an external magnetic field that can adsorb nanomagnetic beads of various magnitudes to separate the magnetic beads from the sample solution. The separation steps of the sample are as follows: the sample solution containing magnetic beads is placed in a centrifuge tube, and after being dispersed by stirring, ultrasound, vibration, etc., the centrifuge tube is placed in the hole position on the magnetic frame, and a certain external magnetic field is applied to the solution by the magnet provided on the magnetic frame, and the magnetic beads in the sample solution will gather on the side close to the magnet, and after there are no dispersed magnetic beads in the solution, the magnetic beads and the sample solution can be quickly separated by removing or pouring the solution. At present, the existing magnetic frames on the market can meet the needs of some customers, but there are still many shortcomings, such as: most of the magnetic frames are designed as an integrated structure, and when performing magnetic separation, mixing operation and pouring out waste liquid, the operator needs to repeatedly transfer a single centrifuge tube one by one, and the synchronous operation of all centrifuge tubes cannot be easily realized. In the process of flipping, shaking and tilting to pour out waste liquid, there is no measure to prevent the centrifuge tube from loosening or falling off, and the safety of the experimental operation cannot be guaranteed. Moreover, the centrifuge tube specifications applicable to the existing magnetic frame are single. In order to meet the centrifuge tubes of different capacities, magnetic frames of different specifications need to be selected, which increases the use cost and reduces the work efficiency. Utility Model Content

[0003] In view of the above defects of the prior art, the purpose of the present application is to provide a magnetic stand that can simultaneously perform magnetic separation, mixing operation and remove waste liquid.

[0004] This application provides the following technical solutions.

[0005] The present application provides a magnetic frame, including a base plate, a first component and a second component, wherein the first component and the second component are both connected to the base plate, the first component is rotatably connected with the connection between the first component and the base plate as an axis, and the second component is rotatably connected with the connection between the first component and the second component as an axis, and a accommodating unit for accommodating the magnetic component is also provided between the first component and the second component; and the first component and the second component are both provided with through holes for storing centrifuge tubes.

[0006] Further, the first component includes a first rotating frame and a first fixed plate, one end of the first rotating frame is connected to the base plate, and the other end of the first rotating frame is connected to the first fixed plate, and the first rotating frame is rotatable around the connection between the first rotating frame and the base plate by an angle of 0°-90°, excluding 0° and 90°; and / or

[0007] The second component includes a second rotating frame and a second fixed plate, one end of the second rotating frame is connected to the base plate, and the other end thereof is connected to the second fixed plate, and the second rotating frame is rotatable around the connection between the second rotating frame and the base plate by an angle of 0°-90°, excluding 0° and 90°.

[0008] Further, the plane where the first rotating frame is located is 45°-120° with the plane where the first fixed plate is located; and / or

[0009] The first fixing plate is provided with two or more first through holes penetrating the first fixing plate, wherein the first through holes are used for placing centrifuge tubes; and / or

[0010] The plane where the second rotating frame is located is 45°-120° with the plane where the second fixed plate is located; and / or

[0011] The second fixing plate is provided with more than two second through holes penetrating the second fixing plate, and the second through holes are used for placing centrifuge tubes.

[0012] Further, a first elastic layer is provided on a surface of one side of the first fixing plate close to the substrate, a first elastic hole corresponding to the first through hole is provided on the first elastic layer, and an inner diameter of the first elastic hole is smaller than an inner diameter of the first through hole; and / or

[0013] A second elastic layer is arranged on a surface of the second fixing plate close to the substrate, a second elastic hole corresponding to the second through hole is arranged on the second elastic layer, and an inner diameter of the second elastic hole is smaller than an inner diameter of the second through hole.

[0014] Furthermore, the first rotating frame and the second rotating frame are both frames that can be extended and retracted in height.

[0015] Furthermore, the first component and the second component are arranged in mirror symmetry.

[0016] Furthermore, the accommodating unit includes a first outer wall and a second outer wall, and the first outer wall is arranged on the base close to the first rotating frame, and the second outer wall is arranged on the base close to the second rotating frame, and the first outer wall and the second outer wall are both perpendicular to the base.

[0017] Furthermore, a groove recessed toward the inside of the base is provided on the base in the accommodating unit, and the groove is used to fix the magnetic component.

[0018] Furthermore, the magnetic assembly includes a fixed frame, on which more than two magnets are detachably arranged at intervals.

[0019] Furthermore, a heating component is also provided on the surface of the substrate away from the first component and the second component.

[0020] In the magnetic rack provided in the present application, since the first component and the second component can be rotatably connected with the connection between them and the base plate as an axis, and centrifuge tubes can be stored on the first component and the second component, when the liquid in the centrifuge tube on the first component or the second component needs to be poured out, it is only necessary to rotate the first component or the second component to pour out the liquid in the centrifuge tube, and since a accommodating unit for accommodating the magnetic component is also provided between the first component and the second component, the magnetic beads in the centrifuge tube will not be poured out during the pouring process. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1 A schematic diagram of the structure of the magnetic rack provided in this application.

[0022] Description of Reference Numerals

[0023] 1-first rotating frame, 2-first fixing plate, 3-first through hole, 4-heating component, 5-first outer wall, 6-second outer wall, 7-second through hole, 8-second fixing plate, 9-base plate, 10-groove. DETAILED DESCRIPTION

[0024] The following is a description of the exemplary embodiments of the present application, including various details of the embodiments of the present application to facilitate understanding, which should be considered as merely exemplary. Therefore, it should be recognized by those of ordinary skill in the art that various changes and modifications can be made to the embodiments described herein without departing from the scope and spirit of the present application. Similarly, for clarity and conciseness, the description of well-known functions and structures is omitted in the following description.

[0025] like Figure 1As shown, the present application provides a magnetic frame, including a substrate 9, a first component and a second component, the first component and the second component are both connected to the substrate 9, the first component is rotatably connected with the connection between the first component and the substrate 9 as an axis, the second component is rotatably connected with the connection between the first component and the second component as an axis, and a accommodating unit for accommodating the magnetic component is also provided between the first component and the second component; the first component and the second component are both provided with through holes for storing centrifuge tubes.

[0026] The first component and the second component rotate in opposite directions. Both the first component and the second component rotate around the connection between the first component and the base plate 9 and rotate in a direction away from the accommodating unit.

[0027] The first component and the second component are independent of each other and do not affect each other's rotation. Whether rotation is required depends on actual needs.

[0028] In the magnetic rack provided in the present application, since the first component and the second component can be rotatably connected with the connection between them and the substrate 9 as an axis, and centrifuge tubes can be stored on the first component and the second component, when the liquid in the centrifuge tube on the first component or the second component needs to be poured out, it is only necessary to rotate the first component or the second component to pour out the liquid in the centrifuge tube, and since a accommodating unit for accommodating the magnetic component is also provided between the first component and the second component, the magnetic beads in the centrifuge tube will not be poured out during the pouring process.

[0029] In the present application, the first component includes a first rotating frame 1 and a first fixed plate 2, one end of the first rotating frame 1 is connected to the substrate 9, and the other end is connected to the first fixed plate 2, and the first rotating frame 1 takes the connection between it and the substrate 9 as the axis, and the rotatable angle is 0°-90°, excluding 0° and 90°.

[0030] Furthermore, a first rotating shaft is provided on the substrate 9 , and the first rotating frame 1 is connected to the first rotating shaft, so that the first rotating frame 1 can rotate around the first rotating shaft.

[0031] Furthermore, the number of the first rotating axes may be 1, 2, 3 or more, which may be determined according to actual needs.

[0032] In some embodiments, when there is one first rotating shaft, the first rotating shaft is connected to the middle of the first rotating frame 1 , and the length of the first rotating shaft is smaller than the length of the first rotating frame 1 .

[0033] In some embodiments, when there is one first rotating shaft, the first rotating shaft is axially connected to the first rotating frame 1 , and the length of the first rotating shaft is equal to the length of the first rotating frame 1 .

[0034] In some embodiments, when there are multiple first rotating shafts, the multiple first rotating shafts are connected to the first rotating frame 1 in sequence and at intervals along the axial direction.

[0035] In some embodiments, the first rotating frame 1 is rotatable at an angle of 10°-80° with the connection between the first rotating frame 1 and the base plate 9 as an axis.

[0036] In some embodiments, the first rotating frame 1 is rotatable at an angle of 10°-70° with the connection between the first rotating frame 1 and the base plate 9 as an axis.

[0037] In some embodiments, the first rotating frame 1 is rotatable at an angle of 10°-60° with the connection between the first rotating frame 1 and the base plate 9 as an axis.

[0038] In some embodiments, the first rotating frame 1 is rotatable by an angle of 10°-50° with the connection between the first rotating frame 1 and the base plate 9 as an axis.

[0039] In some embodiments, the first rotating frame 1 is rotatable by an angle of 10°-40° with the connection between the first rotating frame 1 and the base plate 9 as an axis.

[0040] In some embodiments, the first rotating frame 1 can rotate by an angle of 10°-30° with the connection between the first rotating frame 1 and the base plate 9 as an axis.

[0041] In some embodiments, the first rotating frame 1 can rotate by an angle of 10°-20° with the connection between the first rotating frame 1 and the base plate 9 as an axis.

[0042] In some embodiments, the first rotating frame 1 is rotatable at an angle of 5°-30° with the connection between the first rotating frame 1 and the base plate 9 as an axis.

[0043] Specifically, the first rotating frame 1 takes the connection between it and the base plate 9 as an axis, and the rotatable angle can be 5°, 6°, 7°, 8°, 9°, 10°, 11°, 12°, 13°, 14°, 15°, 16°, 17°, 18°, 19°, 20°, 21°, 22°, 23°, 24°, 25°, 26°, 27°, 28°, 29°, 30°, 31°, 32°, 33°, 34°, 35°, 36°, 37°, 38°, 39°, 40°, 41°, 42°, 43° , 44°, 45°, 46°, 47°, 48°, 49°, 50°, 51°, 52°, 53°, 54°, 55°, 56°, 57°, 58°, 59°, 60°, 61°, 62°, 63°, 64°, 65°, 66°, 67°, 68°, 69°, 70°, 71°, 72°, 73°, 74°, 75°, 76°, 77°, 78°, 79°, 80°, 81°, 82°, 83°, 84°, 85°, 86°, 87°, 88°, 89°, etc.

[0044] When the centrifuge tube on the first assembly needs to be dumped, the first fixing plate 2 is pressed to apply a force to the first fixing plate 2, so that the first fixing plate 2 drives the first rotating frame 1 to rotate about the first rotating axis, so that the first fixing plate 2 tilts toward the side away from the accommodating unit until it tilts to a preset position. The preset position can be determined according to actual needs.

[0045] In the present application, the second component includes a second rotating frame and a second fixed plate 8, one end of the second rotating frame is connected to the base plate 9, and the other end is connected to the second fixed plate 8, and the second rotating frame uses the connection between it and the base plate 9 as an axis, and can rotate at an angle of 0°-90°, excluding 0° and 90°.

[0046] Furthermore, a second rotating shaft is provided on the substrate 9, and the second rotating frame is connected to the second rotating shaft, so that the second rotating frame can rotate around the second rotating shaft.

[0047] Furthermore, the number of the second rotation axes may be 1, 2, 3 or more, which may be determined according to actual needs.

[0048] In some embodiments, when there is one second rotating shaft, the second rotating shaft is connected to the middle of the second rotating frame, and the length of the second rotating shaft is smaller than the length of the second rotating frame.

[0049] In some embodiments, when there is one second rotating shaft, the second rotating shaft is axially connected to the second rotating frame, and the length of the second rotating shaft is equal to the length of the second rotating frame.

[0050] In some embodiments, when there are multiple second rotating shafts, the multiple second rotating shafts are connected to the second rotating frame in sequence and spaced apart along the axial direction.

[0051] In some embodiments, the second rotating frame is rotatable by an angle of 10°-80° with the connection between the second rotating frame and the base plate 9 as an axis.

[0052] In some embodiments, the second rotating frame is rotatable by an angle of 10°-70° with the connection between the second rotating frame and the base plate 9 as an axis.

[0053] In some embodiments, the second rotating frame is rotatable by an angle of 10°-60° with the connection between the second rotating frame and the base plate 9 as an axis.

[0054] In some embodiments, the second rotating frame is rotatable by an angle of 10°-50° with the connection between the second rotating frame and the base plate 9 as an axis.

[0055] In some embodiments, the second rotating frame is rotatable by an angle of 10°-40° with the connection between the second rotating frame and the base plate 9 as an axis.

[0056] In some embodiments, the second rotating frame is rotatable by an angle of 10°-30° with the connection between the second rotating frame and the base plate 9 as an axis.

[0057] In some embodiments, the second rotating frame is rotatable by an angle of 10°-20° with the connection between the second rotating frame and the base plate 9 as an axis.

[0058] In some embodiments, the second rotating frame is rotatable by an angle of 5°-30° with the connection between the second rotating frame and the base plate 9 as an axis.

[0059] Specifically, the second rotating frame takes the connection between it and the base plate 9 as an axis, and the rotatable angle can be 5°, 6°, 7°, 8°, 9°, 10°, 11°, 12°, 13°, 14°, 15°, 16°, 17°, 18°, 19°, 20°, 21°, 22°, 23°, 24°, 25°, 26°, 27°, 28°, 29°, 30°, 31°, 32°, 33°, 34°, 35°, 36°, 37°, 38°, 39°, 40°, 41°, 42°, 43° , 44°, 45°, 46°, 47°, 48°, 49°, 50°, 51°, 52°, 53°, 54°, 55°, 56°, 57°, 58°, 59°, 60°, 61°, 62°, 63°, 64°, 65°, 66°, 67°, 68°, 69°, 70°, 71°, 72°, 73°, 74°, 75°, 76°, 77°, 78°, 79°, 80°, 81°, 82°, 83°, 84°, 85°, 86°, 87°, 88°, 89°, etc.

[0060] When the centrifuge tube on the second assembly needs to be dumped, the second fixing plate 8 is pressed to apply a force to the second fixing plate 8, so that the second fixing plate 8 drives the second rotating frame to rotate about the second rotating axis, so that the second fixing plate 8 tilts toward the side away from the accommodating unit until it tilts to a preset position. The preset position can be determined according to actual needs.

[0061] In the present application, the plane where the first rotating frame 1 is located and the plane where the first fixed plate 2 is located are at an angle of 45°-120°.

[0062] Furthermore, the first rotating frame 1 is fixedly connected to the first fixing plate 2 .

[0063] In some embodiments, the plane where the first rotating frame 1 is located is 50°-100° with the plane where the first fixing plate 2 is located.

[0064] In some embodiments, the plane where the first rotating frame 1 is located is 60°-100° with the plane where the first fixing plate 2 is located.

[0065] In some embodiments, the plane where the first rotating frame 1 is located and the plane where the first fixing plate 2 is located are at an angle of 70°-100°.

[0066] In some embodiments, the plane where the first rotating frame 1 is located and the plane where the first fixing plate 2 is located are at an angle of 80°-100°.

[0067] In some embodiments, the plane where the first rotating frame 1 is located is 90°-100° with the plane where the first fixing plate 2 is located.

[0068] In some embodiments, the plane where the first rotating frame 1 is located is 90° to the plane where the first fixing plate 2 is located.

[0069] In the present application, the first fixing plate 2 is provided with more than two first through holes 3 penetrating the first fixing plate 2. The first through holes 3 are used to place centrifuge tubes.

[0070] The number of the first through holes 3 can be 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, etc., and can be determined according to actual needs.

[0071] Furthermore, a plurality of first through holes 3 are arranged along the length direction of the first fixing plate 2 .

[0072] Furthermore, the plurality of first through holes 3 are arranged at equal intervals.

[0073] The first through hole 3 is located on the center line of the surface of the first fixing plate 2 away from the substrate.

[0074] Furthermore, on the first fixing plate 2, there is only one row of a plurality of first through holes 3 arranged at equal intervals along the length direction thereof.

[0075] In the present application, the plane where the second rotating frame is located is 45°-120° with the plane where the second fixing plate 8 is located.

[0076] Furthermore, the second rotating frame is fixedly connected to the second fixing plate 8 .

[0077] In some embodiments, the plane where the second rotating frame is located is 50°-100° with the plane where the second fixing plate 8 is located.

[0078] In some embodiments, the plane where the second rotating frame is located is 60°-100° with the plane where the second fixing plate 8 is located.

[0079] In some embodiments, the plane where the second rotating frame is located is 70°-100° with the plane where the second fixing plate 8 is located.

[0080] In some embodiments, the plane where the second rotating frame is located is 80°-100° with the plane where the second fixing plate 8 is located.

[0081] In some embodiments, the plane where the second rotating frame is located is 90°-100° with the plane where the second fixing plate 8 is located.

[0082] In some embodiments, the plane where the second rotating frame is located is 90° to the plane where the second fixing plate 8 is located.

[0083] In the present application, the second fixing plate 8 is provided with two or more second through holes 7 penetrating the second fixing plate 8. The second through holes 7 are used to place centrifuge tubes.

[0084] The number of the second through holes 7 can be 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, etc., and can be determined according to actual needs.

[0085] Furthermore, a plurality of second through holes 7 are arranged along the length direction of the second fixing plate 8 .

[0086] Furthermore, the plurality of second through holes 7 are arranged at equal intervals.

[0087] The second through hole 7 is located on the center line of the surface of the second fixing plate 8 away from the substrate.

[0088] Furthermore, on the second fixing plate 8, there is only one row of a plurality of second through holes 7 arranged at equal intervals along the length direction thereof.

[0089] In the present application, a first elastic layer is provided on the surface of one side of the first fixing plate 2 close to the substrate 9, a first elastic hole corresponding to the first through hole 3 is provided on the first elastic layer, and the inner diameter of the first elastic hole is smaller than the inner diameter of the first through hole 3.

[0090] Furthermore, the first elastic layer may be a whole layer continuously disposed on a surface of one side of the first fixing plate 2 close to the substrate 9 .

[0091] Further, the first elastic layer may be a plurality of first elastic units arranged at intervals on a surface of one side of the first fixing plate 2 close to the substrate 9 .

[0092] The first elastic layer has a certain elasticity, and may be formed of a material with elasticity such as foam or rubber.

[0093] The thickness of the first elastic layer may be 0.1 mm-1 mm, for example, 0.1 mm, 0.2 mm, 0.3 mm, 0.4 mm, 0.5 mm, 0.6 mm, 0.7 mm, 0.8 mm, 0.9 mm, 1 mm, etc.

[0094] The inner diameter of the first elastic hole is 0.1mm-5mm, for example, 0.1mm, 0.2mm, 0.3mm, 0.4mm, 0.5mm, 0.6mm, 0.7mm, 0.8mm, 0.9mm, 1mm, 1.1mm, 1.2mm, 1.3mm, 1.4mm, 1.5mm, 1.6mm, 1.7mm, 1.8mm, 1.9mm, 2mm, 2.1mm, 2.2mm, 2.3mm m, 2.4mm, 2.5mm, 2.6mm, 2.7mm, 2.8mm, 2.9mm, 3mm, 3.1mm, 3.2mm, 3.3mm, 3.4mm, 3.5mm, 3.6mm, 3 .7mm, 3.8mm, 3.9mm, 4mm, 4.1mm, 4.2mm, 4.3mm, 4.4mm, 4.5mm, 4.6mm, 4.7mm, 4.8mm, 4.9mm, 5mm, etc.

[0095] The inner diameter of the first through hole 3 is 5mm-15mm, for example, it can be 5mm, 5.5mm, 6mm, 6.5mm, 7mm, 7.5mm, 8mm, 8.5mm, 9mm, 9.5mm, 10mm, 10.5mm, 11mm, 11.5mm, 12mm, 12.5mm, 13mm, 13.5mm, 14mm, 14.5mm, 15mm, etc.

[0096] When the outer diameter of the centrifuge tube is smaller than the inner diameter of the first through hole 3 , the centrifuge tube can be fixed in the first through hole 3 through the first elastic hole, so the magnetic frame can match centrifuge tubes of different diameters.

[0097] In the present application, a second elastic layer is provided on the surface of one side of the second fixing plate 8 close to the substrate 9, a second elastic hole corresponding to the second through hole 7 is provided on the second elastic layer, and the inner diameter of the second elastic hole is smaller than the inner diameter of the second through hole 7.

[0098] Furthermore, the second elastic layer may be a whole layer continuously disposed on a surface of one side of the second fixing plate 8 close to the substrate 9 .

[0099] Further, the second elastic layer may be a plurality of second elastic units arranged at intervals on a surface of one side of the second fixing plate 8 close to the base plate 9 .

[0100] The second elastic layer has a certain elasticity, and may be formed of a material having elasticity such as foam or rubber.

[0101] The thickness of the second elastic layer may be 0.1 mm-1 mm, for example, 0.1 mm, 0.2 mm, 0.3 mm, 0.4 mm, 0.5 mm, 0.6 mm, 0.7 mm, 0.8 mm, 0.9 mm, 1 mm, etc.

[0102] The inner diameter of the second elastic hole is 0.1mm-5mm, for example, 0.1mm, 0.2mm, 0.3mm, 0.4mm, 0.5mm, 0.6mm, 0.7mm, 0.8mm, 0.9mm, 1mm, 1.1mm, 1.2mm, 1.3mm, 1.4mm, 1.5mm, 1.6mm, 1.7mm, 1.8mm, 1.9mm, 2mm, 2.1mm, 2.2mm, 2.3mm m, 2.4mm, 2.5mm, 2.6mm, 2.7mm, 2.8mm, 2.9mm, 3mm, 3.1mm, 3.2mm, 3.3mm, 3.4mm, 3.5mm, 3.6mm, 3 .7mm, 3.8mm, 3.9mm, 4mm, 4.1mm, 4.2mm, 4.3mm, 4.4mm, 4.5mm, 4.6mm, 4.7mm, 4.8mm, 4.9mm, 5mm, etc.

[0103] The inner diameter of the second through hole 7 is 5mm-15mm, for example, it can be 5mm, 5.5mm, 6mm, 6.5mm, 7mm, 7.5mm, 8mm, 8.5mm, 9mm, 9.5mm, 10mm, 10.5mm, 11mm, 11.5mm, 12mm, 12.5mm, 13mm, 13.5mm, 14mm, 14.5mm, 15mm, etc.

[0104] When the outer diameter of the centrifuge tube is smaller than the inner diameter of the second through hole 7, the centrifuge tube can be fixed in the second through hole 7 through the second elastic hole, so the magnetic frame can match centrifuge tubes with different diameters.

[0105] In the present application, the first rotating frame 1 and the second rotating frame are both frames that can be extended and retracted. The structure of the telescopic frame can have a variety of conventional telescopic structures. For example, one of the following:

[0106] The first rotating frame 1 includes a first rotating frame A and a first rotating frame B. The first rotating frame A is connected to the base plate 9 via a first rotating axis, and the first rotating frame B is fixedly connected to the first fixed plate 2. The first rotating frame B is at least partially located in the first rotating frame A along the height direction.

[0107] The first rotating frame A is a hollow structure, and a first fixing hole is provided on the outer wall of the first rotating frame A at one end close to the first rotating frame B, and a slide is provided on the inner wall of the first rotating frame A, and the first fixing hole is located at the end of the slide. An elastic convex buckle is provided on the tube wall of one end of the first rotating frame B close to the first rotating frame A, and the elastic convex buckle is movably provided in the slide. When the height of the first rotating frame 1 needs to be raised, the first rotating frame B is pulled out from the first rotating frame A, and the elastic convex buckle moves along the slide until it reaches the first fixing hole and extends out of the first fixing hole, thereby fixing the first rotating frame B on the first rotating frame A. When the height of the first rotating frame needs to be lowered, the elastic convex buckle is pressed to push it into the slide in the first rotating frame A, and then the first rotating frame B is pushed to restore it to its original position. This design can not only adapt to centrifuge tubes of different heights, but also reduce the height when the magnetic frame needs to be placed in certain instruments.

[0108] The structure of the second rotating frame can refer to the structure of the first rotating frame 1, as follows:

[0109] The second rotating frame includes a second rotating frame A and a second rotating frame B. The second rotating frame A is connected to the base plate 9 via a second rotating shaft, and the second rotating frame B is fixedly connected to the second fixed plate 8. The second rotating frame B is at least partially located in the second rotating frame A along the height direction.

[0110] The second rotating frame A is a hollow structure, and a second fixing hole is provided on the outer wall of the second rotating frame A at one end close to the second rotating frame B, and a slide is provided on the inner wall of the second rotating frame A, and the second fixing hole is located at the end of the slide. An elastic convex buckle is provided on the tube wall of one end of the second rotating frame B close to the second rotating frame A, and the elastic convex buckle is movably provided in the slide. When the height of the second rotating frame needs to be raised, the second rotating frame B is pulled out from the second rotating frame A, and the elastic convex buckle moves along the slide until it reaches the second fixing hole and extends out of the second fixing hole, thereby fixing the second rotating frame B on the second rotating frame A. When the height of the second rotating frame needs to be lowered, the elastic convex buckle is pressed to push it into the slide in the second rotating frame A, and then the second rotating frame B is pushed to restore it to its original position. This design can not only adapt to centrifuge tubes of different heights, but also reduce the height when the magnetic frame needs to be placed in certain instruments.

[0111] In the present application, the first component and the second component are arranged in mirror symmetry with the accommodating unit as a mirror.

[0112] Furthermore, the accommodating unit includes a first outer wall 5 and a second outer wall 6, and the first outer wall 5 is arranged on the base close to the first rotating frame 1, and the second outer wall 6 is arranged on the base close to the second rotating frame, and the first outer wall 5 and the second outer wall 6 are both perpendicular to the base.

[0113] When the magnetic frame is in a non-working state, the first rotating frame 1 and the second rotating frame are both perpendicular to the base. Therefore, the first outer wall 5 is parallel to the first rotating frame 1, and the second outer wall 6 is parallel to the second rotating frame.

[0114] The first outer wall 5 and the second outer wall 6 can both be hollow frame structures or whole plate structures. When the first outer wall 5 and the second outer wall 6 are both hollow frame structures, the magnetic component in the accommodating cavity has a stronger adsorption force on the magnetic beads in the centrifuge tubes in the first through hole 3 and the second through hole 7.

[0115] Furthermore, a groove 10 recessed toward the inside of the base is provided on the base in the containing unit, and the groove 10 is used to fix the magnetic component.

[0116] The magnetic component can be detachably arranged in the accommodating unit. When the magnetic frame is in a non-working state, the magnetic component can be removed from the magnetic frame for separate storage. When the centrifuge tube on the magnetic frame needs to be magnetically attracted, the magnetic component can be placed on the groove 10 in the accommodating unit to fix the magnetic component.

[0117] Furthermore, the magnetic assembly includes a fixed frame, on which more than two magnets are detachably arranged at intervals.

[0118] The fixed frame is provided with more than two slots, and the magnets are embedded in the slots, so as to separate the magnets to avoid mutual influence and displacement. Meanwhile, the magnets arranged at intervals can also reduce the amount of magnets used and reduce costs.

[0119] The magnetic component can provide magnetic force to the magnetic beads in the centrifuge tubes on the first component and the second component at the same time.

[0120] The number of the magnets may be 2, 3, 4, 5, 6, 7, 8, 9, 10, etc., and the number of the magnets may be determined according to actual needs.

[0121] In some embodiments, the magnetic component may also be a whole magnet, and the length of the whole magnet is equal to the distance between the first through hole 3 / the second through hole 7 located at both ends of the first component / the second component.

[0122] In the present application, a heating component 4 is further provided on the surface of the substrate 9 which is away from the first component and the second component.

[0123] The heating component 4 can be used to heat the liquid in the centrifuge tube on the first through hole 3 and the second through hole 7 .

[0124] The heating component 4 is a conventional heating component 4 and is not specifically limited here, as long as it can achieve the functions in the present application, for example, it can be a heating plate, etc.

[0125] In the present application, except for the magnetic component and the heating component 4 , the materials of other parts of the magnetic frame can be transparent materials, such as transparent plastic.

[0126] The magnetic rack described in the present application, when it is needed to be used, insert the centrifuge tube with magnetic beads into the first through hole 3 and the second through hole 7, and the magnetic beads are adsorbed on the inner wall of the centrifuge tube close to the magnetic component under the influence of the magnetic component. When it is necessary to dump the liquid in the centrifuge tube, rotate the first component, and the first rotating frame 1 rotates with the first rotating axis as the axis, so that the first fixed plate 2 rotates to the side away from the first outer wall 5 until it rotates to a suitable angle, and the liquid in all centrifuge tubes on the first through hole 3 is dumped at the same time. After the dumping is completed, the first fixed plate 2 is reset. The dumping process of the centrifuge tube on the second component is similar to the dumping process of the centrifuge tube on the first component and will not be repeated. Since the first through hole 3 of the magnetic rack can be adapted to centrifuge tubes of different diameters, the magnetic rack can also be used as a test tube rack.

[0127] Although the embodiments of the present application are described above in conjunction with the accompanying drawings, the present application is not limited to the above specific embodiments and application fields, and the above specific embodiments are merely illustrative and instructive, rather than restrictive. A person of ordinary skill in the art can also make many forms under the guidance of this specification and without departing from the scope of protection of the claims of the present application, all of which belong to the protection of the present application.

Claims

1. A magnetic frame, characterized in that: It includes a base plate, a first component and a second component, the first component and the second component are both connected to the base plate, the first component is rotatably connected with the connection between the first component and the base plate as an axis, the second component is rotatably connected with the connection between the first component and the base plate as an axis, and a accommodating unit for accommodating a magnetic component is also provided between the first component and the second component; the first component and the second component are both provided with through holes for storing centrifuge tubes.

2. The magnetic frame according to claim 1, wherein: The first component includes a first rotating frame and a first fixed plate, one end of the first rotating frame is connected to the base plate, and the other end of the first rotating frame is connected to the first fixed plate, and the first rotating frame is rotatable at an angle of 0°-90° (excluding 0° and 90°) with the connection between the first rotating frame and the base plate as an axis; and / or The second component includes a second rotating frame and a second fixed plate, one end of the second rotating frame is connected to the base plate, and the other end thereof is connected to the second fixed plate, and the second rotating frame is rotatable around the connection between the second rotating frame and the base plate by an angle of 0°-90°, excluding 0° and 90°.

3. The magnetic frame according to claim 2, wherein: The plane where the first rotating frame is located is 45°-120° with the plane where the first fixed plate is located; and / or The first fixing plate is provided with two or more first through holes penetrating the first fixing plate, wherein the first through holes are used for placing centrifuge tubes; and / or The plane where the second rotating frame is located is 45°-120° with the plane where the second fixed plate is located; and / or The second fixing plate is provided with more than two second through holes penetrating the second fixing plate, and the second through holes are used for placing centrifuge tubes.

4. The magnetic frame according to claim 3, wherein: A first elastic layer is disposed on a surface of the first fixing plate close to the substrate, a first elastic hole corresponding to the first through hole is disposed on the first elastic layer, and an inner diameter of the first elastic hole is smaller than an inner diameter of the first through hole; and / or A second elastic layer is arranged on a surface of the second fixing plate close to the substrate, a second elastic hole corresponding to the second through hole is arranged on the second elastic layer, and an inner diameter of the second elastic hole is smaller than an inner diameter of the second through hole.

5. The magnetic frame according to any one of claims 2 to 4, wherein: The first rotating frame and the second rotating frame are both frames that can be raised and lowered in height.

6. The magnetic frame according to claim 2, wherein: The first component and the second component are arranged in mirror symmetry.

7. The magnetic frame according to claim 2, wherein: The accommodating unit includes a first outer wall and a second outer wall, wherein the first outer wall is disposed on the base plate close to the first rotating frame, and the second outer wall is disposed on the base plate close to the second rotating frame, and both the first outer wall and the second outer wall are perpendicular to the base plate.

8. The magnetic frame according to claim 7, wherein: A groove recessed toward the inside of the substrate is arranged on the substrate in the accommodating unit, and the groove is used to fix the magnetic component.

9. The magnetic frame according to claim 1, wherein: The magnetic assembly includes a fixed frame, on which more than two magnets are detachably arranged at intervals.

10. The magnetic frame according to claim 1, wherein: A heating component is also arranged on the surface of the substrate away from the first component and the second component.

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