An adjustable bile collection device for rats and mice

Abstract

The utility model discloses an adjustable bile collection device for rats and mice, comprising an incubator and a placement slot; a through-hole plate is fixed inside the incubator, a micro-negative pressure pump is evenly distributed on the rear side of the incubator, the liquid inlet pipe of the micro-negative pressure pump is connected to the liquid outlet of the bile collection station, a support frame corresponding to the micro-negative pressure pump is evenly fixed at the bottom end of the rear side of the incubator, the placement slot is evenly opened on the front side of the incubator, and a feeding box is placed inside the placement slot. The adjustable bile collection device for rats and mice adopts a Velcro sub-stick with a Velcro mother-stick so that a fastening belt and a sponge pad can be installed and fixed on mice of different sizes, and the micro-negative pressure pump can be started to transport the bile of the mouse through the bile collection station to the collection bottle inside the support frame, so that bile can be collected from rats and mice to improve the practicality of the device.

Description

Technical Field

[0001] The utility model relates to the technical field of pharmacokinetic experiments, in particular to an adjustable bile collection device for rats and mice. Background Art

[0002] During pharmacokinetic experiments, it is often necessary to collect animal bile for efficacy studies or drug metabolism analysis. The existing patent number CN202699337U discloses a rat bile collection device, which includes a circular feeding cage, a vest, a thin spring tube, a cannula, a rotating shaft, a suspension rod and a collection box. The rats undergoing bile duct cannulation surgery are raised in a circular feeding barrel, and the rats are made to wear a vest, which is connected to the thin spring tube. The cannula passes through the hollow thin spring tube, and the thin spring tube and the cannula pass through the upper part of the circular feeding barrel. The thin spring tube is fixed on the rotating shaft of the suspension rod, and the cannula is introduced into the bile collection box.

[0003] The straps used in the prior art are of fixed specifications, which makes it inconvenient to fix mice of different sizes, and it is not possible to collect bile from multiple mice at the same time, resulting in poor practicability of the device. Therefore, an adjustable bile collection device for rats and mice is proposed. Utility Model Content

[0004] The technical problem to be solved by the utility model is to overcome the existing defects and provide an adjustable bile collection device for rats and mice. The Velcro sub-stick is used in combination with the Velcro mother-stick so that the fastening belt is combined with the sponge pad to install and fix mice of different sizes. The bile of the mouse can be transported to the collection bottle inside the support frame through the bile collection station by starting the micro negative pressure pump. In this way, the bile of rats and mice can be collected, so as to improve the practicability of the device and effectively solve the problems in the background technology.

[0005] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: an adjustable rat and mouse bile collection device, comprising an incubator and a placement tank;

[0006] A through-hole plate is fixed inside the incubator, micro-negative pressure pumps are evenly distributed on the rear side of the incubator, a liquid inlet pipe of the micro-negative pressure pump is connected to a liquid outlet of a bile collection station, a support frame corresponding to the position of the micro-negative pressure pump is evenly fixed to the bottom end of the rear side of the incubator, the placement grooves are evenly opened on the front side of the incubator, a feeding box is placed inside the placement grooves, a baffle is slidably connected in the slide groove on the front side of the incubator, and an adjustment unit is provided on the rear side of the incubator;

[0007] It also includes a controller, which is arranged at the top of the front side of the incubator. The input end of the micro negative pressure pump is electrically connected to the output end of the controller, and the input end of the controller is electrically connected to the output end of an external power supply.

[0008] The sliding baffle fixes the feeding box inside the placement trough, which can provide food and water to the mice. The bile collection station is installed on the back of the mouse. Starting the micro negative pressure pump can collect the mouse's bile into the collection bottle inside the support frame, so that samples can be collected while the mouse is awake.

[0009] Furthermore, the adjustment unit comprises a fixed rail, an adjustment frame, an elastic rope, a sponge pad and a fastening belt, wherein the fixed rail is fixed to the top of the rear side of the incubator, the outer side of the fixed rail is slidably connected with the adjustment frame, the top surface of the adjustment frame is connected to one end of the elastic rope, the other end of the elastic rope is connected to the front side of the top surface of the sponge pad, the top surface of the sponge pad is evenly provided with mounting holes, the mounting holes on the top surface of the sponge pad are installed corresponding to the bile collection station, fastening belts are fixed to both ends of the left side of the sponge pad, the position of the sponge pad is adjusted by sliding the adjustment frame on the outer side of the fixed rail, and mice of different sizes can be fixed with the fastening belt to meet the bile collection needs of rats and mice, and the elastic rope will not restrict the behavior of the mice.

[0010] Furthermore, the adjustment unit also includes a Velcro mother tape and a Velcro sub-tape. There are two Velcro mother tapes and they are respectively fixed on both sides of the top surface of the sponge pad. There are two Velcro sub-tapes and they are respectively installed on the inner sides of the corresponding two fastening straps. The Velcro mother tape and the Velcro sub-tape are bonded to prevent the bile collection station inside the sponge pad from falling off, so as to meet the bile collection needs of rats and mice.

[0011] Furthermore, the adjustment unit also includes elastic protrusions and fixing holes, the elastic protrusions are evenly distributed on the rear side of the fixed rail, the fixing holes are opened on the rear side of the adjustment frame, the elastic protrusions are correspondingly engaged with the fixing holes, and the elastic protrusions are inserted into the fixing holes to fix the position of the adjustment frame.

[0012] Furthermore, it also includes a fixing frame, a partition and an identification plate. The fixing frame is evenly distributed on the top surface of the incubator, the inside of the fixing frame is plugged with a partition, and the left side of the partition is installed with an identification plate. The partition inside the fixing frame can separate and place multiple mice, so that bile can be collected from multiple mice at the same time. At the same time, the position of the partition can be adjusted according to the volume of rats or mice to improve the collection efficiency. The set identification plate makes it convenient for personnel to record and view the information of the placed mice.

[0013] Furthermore, it also includes a through groove and an excrement box. The through groove is opened at the bottom end of the left side of the incubator. The interior of the through groove is slidably connected to the excrement box. The sliding excrement box is convenient for collecting the excrement of mice to solve the inconvenience of subsequent cleaning.

[0014] Compared with the prior art, the beneficial effects of the utility model are:

[0015] 1. The position of the sponge pad can be adjusted by sliding the adjustment frame on the outside of the fixed rail. The mice of different sizes can be fixed with the set fastening belt. The bonding of the Velcro mother patch and the Velcro child patch can prevent the bile collection station inside the sponge pad from falling off, so as to meet the needs of bile collection of rats and mice. The elastic rope will not restrict the behavior of the mice. Starting the micro negative pressure pump can collect the bile of the mice into the collection bottle inside the support frame, so that the samples can be collected when the mice are awake.

[0016] 2. Multiple mice can be separated and placed by the partitions inside the fixed frame, so that bile can be collected from multiple mice at the same time. The position of the partitions can also be adjusted according to the size of rats or mice to improve the collection efficiency. The set identification plate makes it convenient for personnel to record and view the information of the placed mice. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 It is a schematic diagram of the three-dimensional structure of the utility model;

[0018] Figure 2 This is a schematic diagram of the structure of the adjustment unit of the utility model;

[0019] Figure 3 It is a partial enlarged structural schematic diagram of point A of the utility model.

[0020] In the figure: 1 incubator, 2 adjustment unit, 21 fixed rail, 22 adjustment frame, 23 elastic rope, 24 sponge pad, 25 magic mother patch, 26 fastening belt, 27 magic sub-patch, 28 elastic protrusion, 29 fixing hole, 3 through-hole plate, 4 micro negative pressure pump, 5 bile collection station, 6 support frame, 7 placement slot, 8 feeding box, 9 baffle, 10 fixed frame, 11 partition, 12 identification plate, 13 through slot, 14 excrement box, 15 controller. DETAILED DESCRIPTION

[0021] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0022] See also Figure 1-3 ,This embodiment provides a technical solution: an adjustable rat and mouse bile collection device, comprising an incubator 1 and a placement tank 7;

[0023] Among them, a through-hole plate 3 is fixed inside the incubator 1, and micro-negative pressure pumps 4 are evenly distributed on the rear side of the incubator 1. The liquid inlet pipe of the micro-negative pressure pump 4 is connected to the liquid outlet of the bile collection station 5. A support frame 6 corresponding to the position of the micro-negative pressure pump 4 is evenly fixed at the bottom end of the rear side of the incubator 1. A placement groove 7 is evenly opened on the front side of the incubator 1, and a feeding box 8 is placed inside the placement groove 7. A baffle 9 is slidably connected in the slide groove on the front side of the incubator 1. The sliding baffle 9 fixes the feeding box 8 inside the placement groove 7, so that food and water can be provided to the mice. When the micro-negative pressure pump 4 is started, the bile of the mice can be collected into the collection bottle inside the support frame 6, so that samples can be collected when the mice are awake.

[0024] Among them, an adjustment unit 2 is provided on the rear side of the incubator 1, and the adjustment unit 2 includes a fixed rail 21, an adjustment frame 22, an elastic rope 23, a sponge pad 24 and a fastening belt 26. The fixed rail 21 is fixed to the top of the rear side of the incubator 1, and the outer side of the fixed rail 21 is slidably connected with the adjustment frame 22. The top surface of the adjustment frame 22 is connected to one end of the elastic rope 23, and the other end of the elastic rope 23 is connected to the front side of the top surface of the sponge pad 24. The top surface of the sponge pad 24 is evenly provided with mounting holes, and the mounting holes on the top surface of the sponge pad 24 are installed corresponding to the bile collection station 5. Fastening belts 26 are fixed at both ends of the left side of the sponge pad 24. The position of the sponge pad 24 is adjusted by sliding the adjustment frame 22 on the outer side of the fixed rail 21. The fastening belt 26 provided in combination can fix mice of different sizes to meet the needs of bile collection of rats and mice, and the elastic rope 23 will not restrict the behavior of the mice.

[0025] Among them, the adjustment unit 2 also includes a Velcro mother patch 25 and a Velcro sub-patch 27, the Velcro mother patch 25 has two and is respectively fixed on both sides of the top surface of the sponge pad 24, the Velcro sub-patch 27 has two and is respectively installed on the inner sides of the corresponding two fastening belts 26, the Velcro mother patch 25 and the Velcro sub-patch 27 are bonded to prevent the bile collection station 5 inside the sponge pad 24 from falling off, so as to meet the needs of bile collection of rats and mice, the adjustment unit 2 also includes an elastic protrusion 28 and a fixing hole 29, the elastic protrusion 28 is evenly distributed on the rear side of the fixing rail 21, the fixing hole 29 is opened on the rear side of the adjustment frame 22, the elastic protrusion 28 is correspondingly engaged with the fixing hole 29, and the elastic protrusion 28 is inserted into the fixing hole 29 to fix the position of the adjustment frame 22;

[0026] The incubator 1 further includes a controller 15, which is disposed at the top of the front side of the incubator 1. The input end of the micro negative pressure pump 4 is electrically connected to the output end of the controller 15, and the input end of the controller 15 is electrically connected to the output end of an external power supply.

[0027] The incubator 1 also includes a fixing frame 10, a partition 11 and an identification plate 12. The fixing frame 10 is evenly distributed on the top surface of the incubator 1. The fixing frame 10 is plugged with the partition 11 inside. The identification plate 12 is installed on the left side of the partition 11. The partition 11 inside the fixing frame 10 can separate and place multiple mice, so that bile can be collected from multiple mice at the same time. At the same time, the position of the partition 11 can be adjusted according to the volume of rats or mice to improve the collection efficiency. The identification plate 12 is set to facilitate personnel to record and view the information of the placed mice.

[0028] It also includes a through groove 13 and an excrement box 14. The through groove 13 is opened at the bottom end of the left side of the incubator 1. The excrement box 14 is slidably connected inside the through groove 13. The sliding excrement box 14 is convenient for collecting the excrement of mice to solve the inconvenience of subsequent cleaning.

[0029] The working principle of the utility model is as follows:

[0030] First, insert the partition 11 into the interior of the fixing frame 10 according to the number of mice to be placed, so that multiple mice can be placed separately;

[0031] Then, the adjusting frame 22 slides on the outside of the fixing rail 21 to adjust the position of the sponge pad 24, and the elastic protrusion 28 is inserted into the fixing hole 29 to fix the position of the adjusting frame 22. The bile collection station 5 is installed on the back of the mouse, and the sponge pad 24 is pressed on the top surface of the bile collection station 5. The fastening belt 26 provided in combination can fix mice of different sizes to meet the needs of bile collection of rats and mice, and the elastic rope 23 will not restrict the behavior of the mouse, so that bile can be collected from multiple mice at the same time, and the position of the partition 11 can also be adjusted according to the size of the rat or mouse to improve the collection efficiency;

[0032] Finally, the sliding excrement box 14 facilitates the collection of mouse excrement and the like, thereby solving the inconvenience of subsequent cleaning.

[0033] It is worth noting that the controller 15 disclosed in the above embodiment is model S7-200, and the micro negative pressure pump 4 can be freely configured according to the actual application scenario. It is recommended to use a micro negative pressure pump of model YW05. The controller 15 controls the operation of the micro negative pressure pump 4 using a method commonly used in the prior art.

[0034] The above description is only an embodiment of the present invention, and does not limit the patent scope of the present invention. Any equivalent structure or equivalent process transformation made by using the contents of the specification and drawings of the present invention, or directly or indirectly applied in other related technical fields, are also included in the patent protection scope of the present invention.

Claims

1. An adjustable bile collection device for rats and mice, characterized in that: It comprises an incubator (1) and a placement tank (7); A through-hole plate (3) is fixed inside the incubator (1), micro-negative pressure pumps (4) are evenly distributed on the rear side of the incubator (1), the liquid inlet pipe of the micro-negative pressure pump (4) is connected to the liquid outlet of the bile collection station (5), a support frame (6) corresponding to the position of the micro-negative pressure pump (4) is evenly fixed at the bottom end of the rear side of the incubator (1), the placement groove (7) is evenly opened on the front side of the incubator (1), a feeding box (8) is placed inside the placement groove (7), a baffle (9) is slidably connected in the slide groove on the front side of the incubator (1), and an adjustment unit (2) is provided on the rear side of the incubator (1); The incubator (1) further comprises a controller (15), wherein the controller (15) is arranged at the top end of the front side of the incubator (1), the input end of the micro negative pressure pump (4) is electrically connected to the output end of the controller (15), and the input end of the controller (15) is electrically connected to the output end of an external power supply.

2. The adjustable bile collection device for rats and mice according to claim 1, characterized in that: The adjustment unit (2) comprises a fixed rail (21), an adjustment frame (22), an elastic rope (23), a sponge pad (24) and a fastening belt (26); the fixed rail (21) is fixed to the top end of the rear side of the incubator (1); the outer side of the fixed rail (21) is slidably connected to the adjustment frame (22); the top surface of the adjustment frame (22) is connected to one end of the elastic rope (23); the other end of the elastic rope (23) is connected to the front side of the top surface of the sponge pad (24); the top surface of the sponge pad (24) is evenly provided with mounting holes; the mounting holes on the top surface of the sponge pad (24) are mounted correspondingly to the bile collection station (5); and fastening belts (26) are fixed to both ends of the left side of the sponge pad (24).

3. The adjustable bile collection device for rats and mice according to claim 2, characterized in that: The adjustment unit (2) further comprises a Velcro mother tape (25) and a Velcro sub tape (27), wherein the Velcro mother tape (25) is provided in two pieces and is respectively fixed on two sides of the top surface of the sponge pad (24), and the Velcro sub tape (27) is provided in two pieces and is respectively installed on the inner side surfaces of the corresponding two fastening belts (26).

4. The adjustable bile collection device for rats and mice according to claim 2, characterized in that: The adjustment unit (2) further comprises elastic protrusions (28) and fixing holes (29), wherein the elastic protrusions (28) are evenly distributed on the rear side of the fixing rail (21), and the fixing holes (29) are opened on the rear side of the adjustment frame (22), and the elastic protrusions (28) are correspondingly engaged with the fixing holes (29).

5. The adjustable bile collection device for rats and mice according to claim 1, characterized in that: It also comprises a fixing frame (10), a partition (11) and an identification plate (12); the fixing frame (10) is evenly distributed on the top surface of the incubator (1); the partition (11) is inserted into the interior of the fixing frame (10); and the identification plate (12) is installed on the left side of the partition (11).

6. The adjustable rat and mouse bile collection device according to claim 1, characterized in that: It also comprises a through slot (13) and an excrement box (14), wherein the through slot (13) is opened at the bottom end of the left side of the incubator (1), and the excrement box (14) is slidably connected inside the through slot (13).

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