A test tube sample changing device for liquid chromatography-mass spectrometry

Abstract

The utility model discloses a test tube sample changing device for a liquid chromatography-mass spectrometer, and the utility model relates to the technical field of analyzing the components of an organic mixture in a sample in a test tube, and comprises a mounting plate fixedly arranged on the bottom wall of a cavity of the liquid chromatography-mass spectrometer, the left end portion of the mounting plate extending to the left outside the cavity, and a base fixedly arranged on the top surface of the extended end, a feed electric cylinder fixedly arranged on the left end surface of the base, a piston rod of the feed electric cylinder passing through the base, and an L-plate arranged on the extended end, a plurality of through grooves arranged at intervals are opened on the horizontal plate of the L-plate along its length direction, and a mounting assembly for mounting a test tube is arranged directly above each through groove. The beneficial effects of the utility model are: reducing the work intensity of the staff and being able to automatically analyze samples in a plurality of test tubes.

Description

Technical Field

[0001] The utility model relates to the technical field of analyzing the components of an organic mixture in a sample in a test tube, in particular to a test tube sample changing device of a liquid chromatography-mass spectrometry instrument. Background Art

[0002] The liquid chromatography-mass spectrometry used in the laboratory can analyze the components of organic mixtures in samples. Figure 1~Figure 2 As shown, a cavity 2 is provided on the front end surface of the housing of the liquid chromatography-mass spectrometry instrument 1, and a detection rod 3 connected to the cavity 2 is provided inside the liquid chromatography-mass spectrometry instrument 1. The working process of the liquid chromatography-mass spectrometry instrument 1 is as follows:

[0003] S1. The staff first vertically arranges multiple test tubes on the test tube rack, then injects a certain amount of sample into each test tube, and affixes a label on the outer surface of the test tube, on which the sample collection time is recorded;

[0004] S2. The staff member takes out the first test tube 4 from the test tube rack, and then puts the opening of the first test tube 4 on the detection rod 3 of the liquid chromatography-mass spectrometry instrument 1 from bottom to top. Figure 3 As shown, when the detection rod 3 contacts the sample in the test tube 4, the liquid chromatography-mass spectrometry instrument 1 analyzes the components of the organic mixture in the sample in the first test tube 4. When the analysis is completed, the staff puts the first test tube 4 back into the test tube rack;

[0005] S3. The staff repeats the operation of step S2 to continuously analyze the components of the organic mixture in the samples in each test tube 4.

[0006] However, although the components of the organic mixture in the samples in each test tube 4 can be analyzed by the linkage between the test tube rack and the liquid chromatography-mass spectrometer, the following technical defects still exist in actual operation:

[0007] In step S2, the test tubes 4 need to be manually taken out from the test tube rack one by one, and then the openings of the test tubes 4 need to be manually put on the detection rod 3 from bottom to top, so as to analyze the components of the organic mixture in the sample in the test tube 4; and the whole operation is completed manually, which increases the workload of the staff;

[0008] In addition, the number of samples to be analyzed every day is large, and the corresponding number of test tubes 4 is also large. However, it takes a long time to complete the analysis of the samples in all test tubes 4 manually by taking the test tubes 4 one by one, which has the technical defect of low analysis efficiency.

[0009] Therefore, there is an urgent need for a test tube sample changing device that can reduce the workload of staff and automatically analyze samples in multiple test tubes. Utility Model Content

[0010] The utility model aims to overcome the shortcomings of the prior art and provide a test tube sample changing device for a liquid chromatography-mass spectrometer which can reduce the workload of staff and automatically analyze samples in multiple test tubes.

[0011] The purpose of the utility model is achieved through the following technical solutions: a test tube sample changing device for a liquid chromatography-mass spectrometer, comprising a mounting plate fixedly mounted on the bottom wall of a cavity of the liquid chromatography-mass spectrometer, the left end of the mounting plate extending to the left outside the cavity, and a base fixedly mounted on the top surface of the extended end, a feed electric cylinder fixedly mounted on the left end surface of the base, a piston rod of the feed electric cylinder passing through the base, and an L-plate arranged on the extended end, a plurality of through slots arranged at intervals are opened on the horizontal plate of the L-plate along its length direction, and a mounting assembly for mounting a test tube is arranged directly above each through slot;

[0012] The mounting assembly includes a guide cylinder fixedly mounted on the horizontal plate of the L plate and located directly above the through slot, the bottom of the guide cylinder is closed, and a through hole is provided in the closed end, the through hole is located directly above the through slot, a slider matching with the inner cavity thereof is slidably mounted in the guide cylinder, a groove is provided on the top surface of the slider, the groove matches with the outer contour of the lower end of the test tube, and a vertically arranged spring is fixedly provided between the bottom wall of the guide cylinder and the bottom surface of the slider;

[0013] A lifting electric cylinder is fixedly arranged on the top surface of the mounting plate and located in the mold cavity, and a lifting rod is fixedly arranged on the action end of the piston rod of the lifting electric cylinder. The lifting rod is located just below the detection rod of the liquid chromatography-mass spectrometer.

[0014] The vertical plate of the L-plate is fixed on the action end of the piston rod of the feed electric cylinder, and the horizontal plate of the L-plate is located above the vertical plate.

[0015] The distances between every two adjacent through grooves are equal.

[0016] The guide cylinder and the sliding block are both in cylindrical shape.

[0017] Two springs are fixedly arranged between the bottom wall of the guide cylinder and the bottom surface of the sliding block, and the two springs are respectively located on the left and right sides of the through hole.

[0018] The test tube sample changing device also includes a controller, which is electrically connected to the feeding electric cylinder and the lifting electric cylinder via a signal line.

[0019] The utility model has the following advantages: reducing the work intensity of the staff and being able to automatically analyze samples in a plurality of test tubes. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1 It is a front view of a liquid chromatography-mass spectrometer;

[0021] Figure 2 for Figure 1 Left view

[0022] Figure 3 A schematic diagram of putting the opening of the first test tube onto the detection rod of the liquid chromatography-mass spectrometer from bottom to top;

[0023] Figure 4 It is a schematic diagram of the structure of the utility model;

[0024] Figure 5 for Figure 4 A partial cross-sectional view of

[0025] Figure 6 for Figure 4 Left view of;

[0026] Figure 7 It is the structural schematic diagram of L plate;

[0027] Figure 8 It is a schematic diagram of the structure of the installation component;

[0028] Fig. 9 This is the axonometric view of the guide cylinder;

[0029] Fig.10 for Fig. 9 The main cross-sectional diagram of

[0030] Fig.11 This is the axonometric view of the slider;

[0031] Fig.12 for Fig.11 The main cross-sectional diagram of

[0032] Fig.13 A schematic diagram of installing a test tube in each installation component;

[0033] Fig.14 A schematic diagram of a test tube in the installation assembly on the far right entering the detection station;

[0034] Fig.15 A schematic diagram of the lifting rod pressing against the bottom surface of the slider;

[0035] Fig.16 This is a schematic diagram of putting the first test tube on the detection rod;

[0036] In the figure:

[0037] 1-liquid chromatography-mass spectrometry instrument, 2-cavity, 3-detection rod, 4-test tube;

[0038] 5-mounting plate, 6-base, 7-feed electric cylinder, 8-L plate, 9-through slot, 10-mounting assembly, 11-guide cylinder, 12-through hole, 13-slider, 14-groove, 15-spring, 16-lifting electric cylinder, 17-lifting rod. DETAILED DESCRIPTION

[0039] The utility model is further described below in conjunction with the accompanying drawings, and the protection scope of the utility model is not limited to the following:

[0040] like Figure 4 to Figure 12 As shown, a test tube sample changing device for a liquid chromatography-mass spectrometer comprises a mounting plate 5 fixedly mounted on the bottom wall of a cavity 2 of the liquid chromatography-mass spectrometer 1, the left end portion of the mounting plate 5 extends to the left outside the cavity 2, and a base 6 is fixedly mounted on the top surface of the extended end, a feed electric cylinder 7 is fixedly mounted on the left end surface of the base 6, a piston rod of the feed electric cylinder 7 passes through the base 6, and an L-plate 8 is arranged on the extended end, a plurality of spaced through grooves 9 are opened on the horizontal plate of the L-plate 8 along its length direction, the spacing between each two adjacent through grooves 9 is equal, and a mounting assembly 10 for mounting a test tube 4 is arranged directly above each through groove 9; the vertical plate of the L-plate 8 is fixedly mounted on the action end of the piston rod of the feed electric cylinder 7, and the horizontal plate of the L-plate 8 is located above the vertical plate.

[0041] The mounting assembly 10 includes a guide cylinder 11 fixedly mounted on a horizontal plate of the L plate 8 and located directly above the through slot 9. The bottom of the guide cylinder 11 is closed, and a through hole 12 is provided in the closed end. The through hole 12 is located directly above the through slot 9. A slider 13 matching its inner cavity is slidably installed in the guide cylinder 11. A groove 14 is provided on the top surface of the slider 13. The groove 14 matches the outer contour of the lower end of the test tube 4. A vertically arranged spring 15 is fixedly arranged between the bottom wall of the guide cylinder 11 and the bottom surface of the slider 13. Two springs 15 are fixedly arranged between the bottom wall of the guide cylinder 11 and the bottom surface of the slider 13. The two springs 15 are respectively located on the left and right sides of the through hole 12. The guide cylinder 11 and the slider 13 are both cylindrical.

[0042] A lifting electric cylinder 16 is fixedly provided on the top surface of the mounting plate 5 and located in the mold cavity 2 , and a lifting rod 17 is fixedly provided on the active end of the piston rod of the lifting electric cylinder 16 . The lifting rod 17 is located just below the detection rod 3 of the liquid chromatography-mass spectrometry instrument 1 .

[0043] The test tube sample changing device also includes a controller, which is electrically connected to the feed electric cylinder 7 and the lift electric cylinder 16 via a signal line. The staff can control the extension or retraction of the piston rods of the feed electric cylinder 7 and the lift electric cylinder 16 through the controller, which facilitates the operation of the staff.

[0044] The working process of the utility model is as follows:

[0045] S1. The staff takes out a test tube 4 and inserts the test tube 4 into the groove 14 of the slider 13 of the rightmost mounting assembly 10 from top to bottom, thereby installing the first test tube 4. At this time, the upper end of the test tube 4 is outside the guide cylinder 11.

[0046] S2, the staff repeats the operation of step S1 for several times, and then installs a test tube 4 in each installation component 10. Fig.13 As shown;

[0047] S3, the staff injects a certain amount of sample into each test tube 4, and affixes a label on the outer surface of the test tube 4, on which the sample collection time is recorded;

[0048] S4, analysis of the organic mixture components in the sample in the first test tube 4, the specific operation steps are:

[0049] S41, control the piston rod of the feed cylinder 7 to extend to the right, the piston rod drives the L plate 8 to move to the right, the L plate 8 drives each mounting assembly 10 thereon to move to the right synchronously, the mounting assembly 10 drives the test tube 4 installed therein to move to the right synchronously, when the piston rod of the feed cylinder 7 extends to the set stroke, the controller controls the feed cylinder 7 to close, at this time, the test tube 4 in the rightmost mounting assembly 10 just enters the detection station of the liquid chromatography-mass spectrometry instrument 1, as shown in FIG. Fig.14 As shown, at the same time, the through hole 12 of the rightmost mounting assembly 10 is just above the jacking rod 17;

[0050] S42, the piston rod of the lifting electric cylinder 16 is controlled to extend upward, and the piston rod drives the lifting rod 17 to move upward, and the lifting rod 17 passes through the rightmost through groove 9 and the through hole 12 of the rightmost mounting assembly 10 in sequence, and finally presses against the bottom surface of the slider 13, as shown in FIG. Fig.15 As shown; as the lifting rod 17 continues to move upward, the lifting rod 17 lifts the slider 13 of the rightmost mounting assembly 10 upward, the slider 13 drives the test tube 4 to move upward, and the test tube 4 moves toward the detection rod 3, while the slider 13 stretches the spring 15 upward;

[0051] When the piston rod of the lifting electric cylinder 16 is fully extended, the test tube 4 is just placed on the detection rod 3. Fig.16 As shown, the detection rod 3 contacts the sample in the test tube 4. At this time, the liquid chromatography-mass spectrometry instrument 1 analyzes the components of the organic mixture in the sample in the first test tube 4, thereby finally completing the analysis of the components of the organic mixture in the sample in the first test tube 4.

[0052] S43, after analysis, the piston rod of the lifting electric cylinder 16 is controlled to retract downward, and the piston rod drives the lifting rod 17 to move downward. When the lifting rod 17 is moving downward, the slider 13 moves downward along the guide cylinder 11 under the elastic restoring force of the spring 15; when the piston rod of the lifting electric cylinder 16 is completely retracted, the controller controls the lifting electric cylinder 16 to close;

[0053] S5. The staff repeats the operation of step S4 to continuously analyze the samples in the test tubes 4 on each installation component 10.

[0054] Among them, it can be seen from steps S3~S4 that the test tube sample changing device only needs to install multiple test tubes 4 in each installation component 10 respectively, and then control the linkage cooperation of the feed electric cylinder 7 and the lifting electric cylinder 16, so as to gradually put each test tube 4 on the detection rod 3 to analyze the components of the organic mixture in the sample in each test tube 4.

[0055] It can be seen that the sample changing device does not need to manually take out the test tubes 4 from the test tube rack one by one, and then manually put the opening of the test tube 4 on the detection rod 3 from bottom to top, but can automatically analyze the samples in multiple test tubes 4, thereby greatly reducing the work intensity of the staff. In addition, it also realizes the analysis of the organic mixture components in the samples in multiple test tubes 4 in a short time, thereby greatly improving the analysis efficiency.

[0056] Finally, it should be noted that the above description is only a preferred embodiment of the utility model and is not intended to limit the utility model. Although the utility model is described in detail with reference to the above embodiments, those skilled in the art can still modify the technical solutions recorded in the above embodiments or replace some of the technical features therein by equivalents. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the utility model shall be included in the protection scope of the utility model.

Claims

1. A test tube sample changing device for a liquid chromatography-mass spectrometer, characterized in that: It comprises a mounting plate (5) fixedly mounted on the bottom wall of a cavity (2) of a liquid chromatography-mass spectrometry instrument (1), the left end of the mounting plate (5) extending to the left outside the cavity (2), and a base (6) fixedly mounted on the top surface of the extended end, a feed electric cylinder (7) fixedly mounted on the left end surface of the base (6), a piston rod of the feed electric cylinder (7) passing through the base (6), and an L-plate (8) disposed on the extended end, a plurality of through slots (9) arranged at intervals are formed on the horizontal plate of the L-plate (8) along its length direction, and a mounting assembly (10) for mounting a test tube (4) is disposed directly above each through slot (9); The mounting assembly (10) comprises a guide cylinder (11) fixedly mounted on a horizontal plate of the L plate (8) and located directly above the through slot (9); the bottom of the guide cylinder (11) is closed, and a through hole (12) is provided in the closed end; the through hole (12) is located directly above the through slot (9); a slider (13) matching with the inner cavity of the guide cylinder (11) is slidably mounted in the guide cylinder (11); a groove (14) is provided on the top surface of the slider (13); the groove (14) matches with the outer contour of the lower end of the test tube (4); a vertically arranged spring (15) is fixedly mounted between the bottom wall of the guide cylinder (11) and the bottom surface of the slider (13); A lifting electric cylinder (16) is fixedly provided on the top surface of the mounting plate (5) and located in the mold cavity (2), and a lifting rod (17) is fixedly provided on the active end of the piston rod of the lifting electric cylinder (16). The lifting rod (17) is located directly below the detection rod (3) of the liquid chromatography-mass spectrometry instrument (1).

2. The test tube sample changing device for liquid chromatography-mass spectrometry according to claim 1, characterized in that: The vertical plate of the L-plate (8) is fixedly arranged on the action end of the piston rod of the feed electric cylinder (7), and the horizontal plate of the L-plate (8) is located above the vertical plate.

3. The test tube sample changing device for liquid chromatography-mass spectrometry according to claim 1, characterized in that: The distance between each two adjacent through grooves (9) is equal.

4. The test tube sample changing device for liquid chromatography-mass spectrometry according to claim 1, characterized in that: The guide cylinder (11) and the sliding block (13) are both cylindrical in shape.

5. The test tube sample changing device for liquid chromatography-mass spectrometry according to claim 1, characterized in that: Two springs (15) are fixedly arranged between the bottom wall of the guide cylinder (11) and the bottom surface of the slider (13), and the two springs (15) are respectively located on the left and right sides of the through hole (12).

6. The test tube sample changing device for liquid chromatography-mass spectrometry according to claim 1, characterized in that: The test tube sample changing device also includes a controller, which is electrically connected to the feeding electric cylinder (7) and the lifting electric cylinder (16) via a signal line.

Images