Bubble detection device for liquid pipeline and sample analyzer

Abstract

The embodiment of the utility model discloses a bubble detection device and sample analyzer of liquid pipeline, bubble detection device at least includes: sensing module, constant current drive module, signal processing module and master control module, the sensing module is used for being arranged on the liquid pipeline, the input end of sensing module is electrically connected with the output end of constant current drive module, and the signal processing module is electrically connected with the master control module. The output end of the sensing module is electrically connected with the input end of the signal processing module; the output end of the signal processing module is electrically connected with the input end of the main control module, and the input end of the constant current driving module is electrically connected with the output end of the main control module. Through the device, the sensing module can realize constant-current driving, so that the sensing module can keep a stable state, acquired signals are amplified and then input into a master controller, and different magnification times can be set, so that the bubble detection device can be compatible with different pipelines and reagents during bubble detection, and the detection accuracy is improved. Different pipeline conditions can be kept consistent in circuit design, and the purpose of saving cost is achieved.

Description

Technical Field

[0001] The utility model relates to the technical field of detection equipment, in particular to a bubble detection device for a liquid pipeline and a sample analyzer. Background Art

[0002] In medical IVD (full name: in vitro diagnostic products, Chinese translation: in vitro diagnostic products) clinical testing instruments, high requirements are generally placed on the accuracy of liquid reagent sample addition. However, bubbles and other air segments often appear in liquid pipelines (referred to as liquid pipes), affecting the reagent sample addition amount. It is necessary to detect and evacuate the bubbles or air to keep a continuous liquid column in the liquid pipe to ensure sample addition accuracy.

[0003] However, due to the complex piping conditions of the instrument's liquid circuit, such as different colors, components, and turbidity of reagents in the liquid circuit, or aging of the pipeline after a period of use, discoloration of the liquid tube, accumulation of impurities on the liquid wall, etc., the bubble detection is not compatible with the above-mentioned complex piping conditions, which requires more circuit design costs and instrument maintenance costs. Utility Model Content

[0004] The main purpose of the utility model is to provide a bubble detection device and a sample analyzer for a liquid pipeline, which can solve the problem in the prior art that due to the complex pipeline conditions of the instrument liquid pipeline, the above-mentioned complex pipeline conditions cannot be compatible with each other when detecting bubbles, which requires more circuit design costs and instrument maintenance costs.

[0005] To achieve the above-mentioned purpose, the utility model provides a bubble detection device for a liquid pipeline in a first aspect, the bubble detection device at least comprising: a sensor module, a constant current drive module, a signal processing module and a main control module, the sensor module is used to be arranged on the liquid pipeline, the input end of the sensor module is electrically connected to the output end of the constant current drive module, the output end of the sensor module is electrically connected to the input end of the signal processing module; the output end of the signal processing module is electrically connected to the input end of the main control module, and the input end of the constant current drive module is electrically connected to the output end of the main control module;

[0006] The main control module is used to output a power control signal to the constant current drive module;

[0007] The constant current driving module is used to receive the power control signal and output a constant current driving signal to the sensor module;

[0008] The sensing module is used to receive the constant current driving signal, output a first sensing signal to the liquid pipeline, and receive and output a second sensing signal to the signal processing module, wherein the second sensing signal is a signal obtained after the first sensing signal passes through the liquid pipeline;

[0009] The signal processing module is used to receive the second sensing signal and output a third sensing signal to the main control module, wherein the third sensing signal is an amplified second sensing signal;

[0010] The main control module is used to receive the third sensing signal and output a target judgment result, where the target judgment result is used to reflect whether there are bubbles in the liquid pipeline.

[0011] To achieve the above-mentioned object, the second aspect of the present invention provides a sample analyzer, which at least includes a liquid pipeline and a bubble detection device for the liquid pipeline as described in the first aspect.

[0012] The following beneficial effects are achieved by using the embodiments of the present invention:

[0013] The utility model provides a bubble detection device for a liquid pipeline, which at least comprises: a sensing module, a constant current driving module, a signal processing module and a main control module. The sensing module is used to be arranged on the liquid pipeline, the input end of the sensing module is electrically connected to the output end of the constant current driving module, and the output end of the sensing module is electrically connected to the input end of the signal processing module; the output end of the signal processing module is electrically connected to the input end of the main control module, and the input end of the constant current driving module is electrically connected to the output end of the main control module; the main control module is used to output a power control signal to the constant current driving module; the constant current driving module is used to receive the power control signal and output the constant current driving signal to the sensing module; the sensing module is used to receive the constant current driving signal, output a first sensing signal to the liquid pipeline, and receive and output a second sensing signal to the signal processing module, the second sensing signal being a signal after the first sensing signal passes through the liquid pipeline; the signal processing module is used to receive the second sensing signal, output a third sensing signal to the main control module, the third sensing signal being the amplified second sensing signal; the main control module is used to receive the third sensing signal and output a target judgment result, the target judgment result being used to reflect whether there are bubbles in the liquid pipeline.

[0014] Through the above device, the sensor module can achieve constant current drive, so that the sensor module can maintain a stable state. The collected signal is input into the main control after amplification processing. Different amplification factors can be set for liquid pipelines in different states, so that the above bubble detection device can be compatible with different pipelines and reagents, and the circuit design of different pipeline conditions can maintain consistency, thereby achieving the purpose of cost saving. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] In order to more clearly illustrate the embodiments of the utility model or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0016] in:

[0017] Figure 1 This is a structural schematic diagram of a bubble detection device for a liquid pipeline in an embodiment of the utility model;

[0018] Figure 2 Another structural schematic diagram of a bubble detection device for a liquid pipeline in an embodiment of the utility model;

[0019] Figure 3 It is another structural schematic diagram of a bubble detection device for a liquid pipeline in an embodiment of the utility model;

[0020] Figure 4 This is a circuit schematic diagram of a bubble detection device for a liquid pipeline in an embodiment of the utility model;

[0021] Figure 5 It is a structural schematic diagram of a sample analyzer in an embodiment of the utility model. DETAILED DESCRIPTION

[0022] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments of the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0023] See also Figure 1 , Figure 1 FIG. 1 is a schematic diagram of a bubble detection device for a liquid pipeline in an embodiment of the utility model. Figure 1 The bubble detection device 00 shown includes at least: a main control module 10 , a constant current driving module 20 , a sensor module 30 and a signal processing module 40 .

[0024] Among them, the sensor module 30 is used to be arranged on the liquid pipeline, the input end of the sensor module 30 is electrically connected to the output end of the constant current drive module 20, and the output end of the sensor module 30 is electrically connected to the input end of the signal processing module 40; the output end of the signal processing module 40 is electrically connected to the input end of the main control module 10, and the input end of the constant current drive module 20 is electrically connected to the output end of the main control module 10; exemplary, the main control module 10 can be a single-chip microcomputer, a field programmable gate array (FieldProgrammable Gate Array, FPGA), a micro control unit (Micro Control Unit, MCU), etc., which have data processing and control capabilities. Control chip, device or equipment, this application is exemplified by the main control module as MCU. The sensor module 30 can be any one of infrared, ultrasonic and capacitive sensors, and this embodiment is exemplified by an infrared sensor.

[0025] Specifically, the main control module 10 is used to output a power control signal to the constant current drive module 20. When the sensor module 30 needs to work, the main control module can send a power control signal to the constant current drive module to enable the sensor module 30 to be powered on to collect data. For example, the power control signal can be an electronic signal for turning on or off the sensor module.

[0026] The constant current drive module 20 is used to receive a power control signal and output a constant current drive signal to the sensor module 30, wherein the constant current drive module can receive a power control signal and output a constant current drive signal to the sensor module to drive the working state of the sensor module with a constant current. For example, if the power control signal is to turn on the sensor module, the working state of the constant current drive sensor module is to start working, so that the sensor module is powered on and works. Exemplarily, the constant current drive signal can be a constant current of 11.3mA to power the sensor.

[0027] The sensing module 30 is used to receive a constant current driving signal, output a first sensing signal to the liquid pipeline, and receive and output a second sensing signal to the signal processing module 40, wherein the second sensing signal is a signal after the first sensing signal passes through the liquid pipeline; wherein, if the sensing module is an infrared sensor, the sensing signal may be a light signal, and if the sensing module is an ultrasonic sensor, the sensing signal may be an ultrasonic signal, which is not limited here. Taking an infrared sensor as an example, the infrared sensor includes a light-emitting side and a light-receiving side, which are arranged on opposite sides of the pipeline, the light-emitting side can emit a light signal, and the light-receiving side can receive a light signal. After power is turned on, the light-emitting side will emit a first light signal to the liquid pipeline, and after passing through the liquid pipeline, the light-receiving side will receive the second light signal. When a medium flows through the pipeline and passes through the light emitted by the infrared sensor, the second light signal will be different depending on the type of the medium. Based on this, the medium condition in the liquid pipeline can be judged, such as whether it is liquid or bubbles.

[0028] The signal processing module 40 is used to receive the second sensing signal and output the third sensing signal to the main control module 10, wherein the signal processing module 40 can perform signal amplification processing to amplify the second sensing signal, so the third sensing signal is the amplified second sensing signal; the main control module 10 is used to receive the third sensing signal and determine the target judgment result, and the target judgment result is used to reflect whether there are bubbles in the liquid pipeline. For example, the main control module can judge whether the medium passing through is liquid or bubbles based on the strength of the sensing signal of the third sensing signal. In order to meet different liquid circuit conditions, the present application sets a signal processing module to perform signal amplification processing on the second sensing signal, and judges the strength of the sensing signal based on the amplified third sensing signal to determine the target judgment result. The target judgment result can be a level signal, with bubbles as a high level and no bubbles as a low level, wherein the sensing signal has different degrees of loss in different media, so the sensing signal can be distinguished based on the strength of the sensing signal. When passing through the liquid pipeline, the type of medium passed is liquid or bubbles. The magnification factor can be set as needed to adapt to different liquid circuit conditions. For example, a sensing signal strength threshold is preset, and the threshold can reflect the critical threshold of the sensing signal passing through the liquid and the bubble. For example, the strength of the received signal is different when the light passes through the liquid segment and the bubble air segment. When the liquid segment is collected, the received light signal is obviously weaker than that in the bubble segment. Continuing to take the sensing signal as a light signal as an example, if the third light signal is greater than the light signal strength threshold at this time, it is considered that the medium type through which the light passes is bubbles, the target judgment result is that bubbles exist, and the output target judgment result is a high-level signal; if the third light signal is less than or equal to the light signal strength threshold at this time, it is considered that the medium type through which the light passes is liquid, the target judgment result is that there are no bubbles, and the output target judgment result is a low-level signal.

[0029] The utility model provides a bubble detection device for a liquid pipeline, which at least comprises: a sensing module, a constant current driving module, a signal processing module and a main control module. The sensing module is used to be arranged on the liquid pipeline, the input end of the sensing module is electrically connected to the output end of the constant current driving module, and the output end of the sensing module is electrically connected to the input end of the signal processing module; the output end of the signal processing module is electrically connected to the input end of the main control module, and the input end of the constant current driving module is electrically connected to the output end of the main control module; the main control module is used to output a power control signal to the constant current driving module; the constant current driving module is used to receive the power control signal and output the constant current driving signal to the sensing module; the sensing module is used to receive the constant current driving signal, output a first sensing signal to the liquid pipeline, and receive and output a second sensing signal to the signal processing module, the second sensing signal being a signal after the first sensing signal passes through the liquid pipeline; the signal processing module is used to receive the second sensing signal, output a third sensing signal to the main control module, the third sensing signal being the amplified second sensing signal; the main control module is used to receive the third sensing signal and output a target judgment result, the target judgment result being used to reflect whether there are bubbles in the liquid pipeline. Through the above device, the sensor module can achieve constant current drive, so that the sensor module can maintain a stable state, the collected signal is input into the main control after amplification, and different amplification factors can be set for liquid pipelines in different states, so that the above bubble detection device can be compatible with different pipelines and reagents, and the circuit design of different pipeline conditions can be consistent, so as to achieve the purpose of cost saving.

[0030] See also Figure 2 , Figure 2 FIG. 2 is another structural schematic diagram of a bubble detection device for a liquid pipeline in an embodiment of the utility model. Figure 2 The bubble detection device shown at least includes: a sensor module 30, a constant current drive module 20, a signal processing module 40 and a main control module 10, the sensor module 30 is used to be arranged on the liquid pipeline, the input end of the sensor module 30 is electrically connected to the output end of the constant current drive module 20, and the output end of the sensor module 30 is electrically connected to the input end of the signal processing module 40; the output end of the signal processing module 40 is electrically connected to the input end of the main control module 10, and the input end of the constant current drive module 20 is electrically connected to the output end of the main control module 10. Further, the signal processing module 40 at least includes a signal preprocessing module 42 and a signal amplification module 41 connected in sequence, the input end of the signal processing module 40 is the input end of the signal preprocessing module 42, and the output end of the signal processing module 40 is the output end of the signal amplification module 41; the output end of the sensor module 30 is electrically connected to the input end of the signal preprocessing module 42; the output end of the signal amplification module 41 is electrically connected to the input end of the main control module 10.

[0031] Among them, the main control module 10 is used to output a power control signal to the constant current drive module 20; the constant current drive module 20 is used to receive the power control signal and output a constant current drive signal to the sensor module 30; the sensor module 30 is used to receive the constant current drive signal, output a first sensing signal to the liquid pipeline, and receive and output a second sensing signal to the signal processing module 40, the second sensing signal is the signal after the first sensing signal passes through the liquid pipeline; the signal processing module 40 is used to receive the second sensing signal and output a third sensing signal to the main control module 10, wherein the third sensing signal is the amplified second sensing signal; the main control module 10 is used to receive the third sensing signal and output a target judgment result, and the target judgment result is used to reflect whether there are bubbles in the liquid pipeline.

[0032] It should be noted that Figure 2 The sensing module 30, constant current driving module 20, signal processing module 40 and main control module 10 in the embodiment are similar to Figure 1 The sensing module 30, the constant current driving module 20, the signal processing module 40 and the main control module 10 are similar in content, and are not described here to avoid repetition. For details, please refer to Figure 1 The sensing module 30, constant current driving module 20, signal processing module 40 and main control module 10 are included in the embodiment.

[0033] In a feasible implementation, the signal processing module at least includes a signal preprocessing module 42 and a signal amplifying module 41. Preprocessing can be performed before amplifying the signal. The signal preprocessing module 42 is used to receive the second sensing signal, output the preprocessed second sensing signal, and input the preprocessed second sensing signal to the signal amplifying module, wherein the preprocessing at least includes signal enhancement processing and / or signal filtering processing; the signal amplifying module 41 is used to receive the preprocessed second sensing signal, and output the third sensing signal to the main control module. Specifically, the signal preprocessing module 42 can preprocess the second sensing signal to obtain the preprocessed second sensing signal, and input the preprocessed second sensing signal to the signal amplifying module, wherein the preprocessing at least includes signal enhancement processing and signal filtering processing;

[0034] The signal amplifying module 41 amplifies the preprocessed second sensing signal according to a preset amplification gain multiple, and outputs a third sensing signal to the main control module 10 .

[0035] In a feasible implementation, the gain multiple can be adjusted by a digital potentiometer, that is, the bubble detection device can also include a digital potentiometer, the input end of the digital potentiometer is electrically connected to the output end of the main control module, and the output end of the digital potentiometer is electrically connected to the input end of the signal amplification module. The main control module can receive the user's interactive operation of gain adjustment, and output the corresponding gain adjustment instruction to the digital potentiometer, and the gain adjustment instruction carries the amplification gain multiple. Then, the digital potentiometer is used to receive the gain adjustment instruction sent by the main control module, and output the gain adjustment signal to the signal amplification module, so that the signal amplification module can amplify the second sensing signal based on the amplification gain multiple set by the user.

[0036] For further information, see Figure 3 , Figure 3 FIG. 1 is another structural schematic diagram of a bubble detection device for a liquid pipeline in an embodiment of the utility model, as shown in FIG. Figure 3 The utility model shown can be regarded as a detection and feedback control system device. It is composed of a bubble sensor with a liquid path, a constant current drive circuit, an analog model input and an adjustable model amplification processing circuit, AD voltage signal acquisition, and MCU data acquisition modules. The purpose is that the sensor can achieve constant current drive, so that the sensor can maintain a stable state. The data acquisition adopts an adjustable amplification method to be compatible with different pipelines and reagents, and the circuit design can be consistent to achieve the purpose of cost saving. Figure 3 The sensor interface, constant current drive module 20, main control module (MCU) 10, digital potentiometer and signal processing module of the above-mentioned sensor module are shown. Specifically, the bubble sensor (the above-mentioned various sensors) is connected during use, and the bubble sensor itself is stuck in the pipeline. When the sensor is powered on, the light-emitting side of the sensor emits a stable light signal under the constant current drive circuit, and the light is received by the light-receiving side of the sensor through the pipeline. In the case of bubbles or liquids, the light-receiving side collects different signals, which are used to distinguish whether the pipeline flows through bubbles or liquids. Then the collected small signal enters the signal processing module. Since the pipelines are different and the liquids flowing through are different, it is necessary to make adjustable processing for the collected signals. In the output signal processing, the operational amplifier is used to follow, filter and amplify. The amplification multiple gain ratio is adjusted by the digital potentiometer. The software program can set a reasonable amplification gain to achieve the situation of compatible pipelines being different and aging and discoloration. Among them, the MCU processes the data collected by the channel and uploads it to the host computer interface. In the entire control feedback system, the circuit voltage can be detected to eliminate the influence of voltage instability on signal acquisition.

[0037] Furthermore, the bubble detection device further comprises an ADC module, the input end of the ADC module is electrically connected to the output end of the signal processing module, and the output end of the ADC module is electrically connected to the input end of the main control module;

[0038] Among them, the ADC module is used to collect the third sensing signal and output the third sensing signal after analog-to-digital conversion to the main control module; then the main control module is specifically used to receive the third sensing signal after analog-to-digital conversion and output the target judgment result.

[0039] Furthermore, the ADC module at least includes a first ADC chip and a second ADC chip, the output end of the signal processing module is electrically connected to the input end of the first ADC chip and the input end of the second ADC chip, respectively, the output end of the first ADC chip and the output end of the second ADC chip are electrically connected to the input end of the main control module, the ADC chip is used to collect the third sensing signal, and output the third sensing signal after analog-to-digital conversion to the main control module; the first ADC chip is used to collect the third sensing signal when the state of the liquid pipeline is stable, and output the third sensing signal after analog-to-digital conversion to the main control module; the second ADC chip is used to collect the third sensing signal when the state of the liquid pipeline is unstable, and output the third sensing signal after analog-to-digital conversion to the main control module, wherein whether the state of the liquid pipeline is stable depends on bubbles or other problems that affect the liquid circuit, and the prompt signal corresponding to whether the state of the liquid pipeline is stable can be determined by the ADC according to the amount of collected signals, or the main control module can make feedback to the ADC module according to the amount of received signals, which is not limited here. For example, refer to Figure 3 , the first ADC chip can be an off-chip ADC of the MCU, and the second ADC chip can be an on-chip ADC of the MCU, that is, the AD voltage signal acquisition is divided into off-chip ADC and on-chip ADC. The difference between the two ADCs is that the acquisition signal accuracy and speed of the two types of ADC modules are different. The accuracy and data conversion speed of the off-chip ADC are generally higher than those of the built-in MCU. The on-chip ADC is generally used in relatively stable conditions such as when there are no bubbles in the pipeline; when a continuous bubble segment is identified, an external ADC module is used to increase the acquisition speed and sensitivity, so that the two ADC chips can work alternately.

[0040] Among them, following is the first step of small signal processing, and its main function is to increase the input impedance of the signal, enhance the signal's anti-interference and stability, and achieve the purpose of input and output isolation. Filtering is the second step. At this time, the signal has more ripple and noise interference. Active low-pass filtering is generally used to filter out the high-frequency noise in the signal to obtain a relatively pure and stable signal; the third step is to amplify the signal. The input of the signal is still relatively weak. By amplifying the signal, a signal with a wider range of variation is obtained, which has better resolution for AD acquisition. The gain of the amplification is determined by the actual sampling range, and the size of this gain can be adjusted by a digital potentiometer. Among them, the adjustment of the digital potentiometer in the multi-channel liquid path bubble detection can be hung on the same bus by communication, saving the IO port resources of the MCU and saving costs.

[0041] For example, the amplification of the input signal. For example, the maximum signal input may be 500mV, and the reference voltage of the AD module is 4V. The potentiometer can be adjusted to change the amplification gain multiple, which can be amplified by about 8 times, but it is best not to exceed the upper limit of the sampling range. By adjusting the multiples of each channel, the channels of the pipeline passing through the liquid are kept consistent.

[0042] For further information, see Figure 4 , Figure 4 This is a circuit schematic diagram of a bubble detection device for a liquid pipeline in an embodiment of the utility model, wherein: Figure 4 The drive and signal input of the sensor are shown.

[0043] The sensor module includes at least one of infrared, ultrasonic and capacitive sensors, and a sensor interface J1 of the sensor. The output end of the constant current drive module is electrically connected to the power supply pin 1 of the sensor interface J1, and the input end of the signal preprocessing module is electrically connected to the output pin 3 of the sensor interface J1. The sensor interface J1 includes pins 1 to 5, wherein pin 1 is a power supply 5V pin, pin 2 is a GND pin, pin 3 is a pin for inputting a signal to the main control, pin 4 is a 5V pin, and pin 5 is a shielding ground pin.

[0044] The constant current driving module at least includes a constant current driving chip, a first resistor R1, a second resistor R8, a third resistor R9, a fourth resistor R10, a diode D1 and a MOS tube Q2;

[0045] The input end of the constant current drive module is the input pin of the constant current drive chip, the output end of the constant current drive module is one end of the first resistor R1, one end of the first resistor R1 is electrically connected to the power supply pin 1 of the sensor interface J1, and the input pin of the constant current drive chip is electrically connected to the output end of the main control module;

[0046] The other end of the first resistor R1 is electrically connected to one end of the second resistor R8, the power supply voltage end signal_VCC of the sensor, and the drain of the MOS tube Q2. The other end of the second resistor R8 is electrically connected to the positive electrode of the diode D1, and the negative electrode of the diode D1 is grounded. The gate of the MOS tube Q2 is electrically connected to one end of the third resistor R9 and one end of the fourth resistor R10, respectively. The other end of the third resistor R9 is electrically connected to the source of the MOS tube Q2, and the other end of the fourth resistor R10 is electrically connected to the output pin S_PWR of the constant current driver chip. Among them, singal_VCC is the power input of the light-emitting side of the sensor. Whether the diode on the light-emitting side is powered on is controlled by the S_PWR signal. When the pipeline status is to be detected, the sensor is powered on, and the indicator light D1 can prompt whether the sensor is powered on. The S_PWR signal is a sensor power control signal, and the signal function is to control the power supply of the sensor.

[0047] Wherein, the signal preprocessing module at least includes an inductor L1, a first capacitor C3, a second capacitor C4, a third capacitor C5 and a fourth capacitor C6;

[0048] The input end of the signal preprocessing module is one end of the inductor L1, and the output end of the signal preprocessing module is one end of the fourth capacitor C6. One end of the inductor L1 is electrically connected to the output pin 3 of the sensor interface, and one end of the fourth capacitor C6 is electrically connected to the input end of the signal amplification module; wherein, Signal is the light signal collected by the light receiving side after preprocessing, which is used to be input into the signal amplification module for amplification processing. This signal is the original signal input by the light receiving side of the sensor. This signal is an analog signal and will change with the change of the received light intensity.

[0049] The other end of the inductor L1 is electrically connected to one end of the first capacitor C3, one end of the second capacitor C4, one end of the third capacitor C5 and one end of the fourth capacitor C6, respectively, and the other end of the first capacitor C3, the other end of the second capacitor C4, the other end of the third capacitor C5 and the other end of the fourth capacitor C6 are all grounded.

[0050] Among them, the bubble detection device also includes a voltage stabilizing module, which includes at least a voltage stabilizing source U3 and a fifth resistor R6. The ground pin 2 of the sensor interface is electrically connected to one end of the fifth resistor R6 and the input pin 1 of the voltage stabilizing source respectively. The power supply pin 1 of the sensor interface is electrically connected to the output pin 3 of the voltage stabilizing source. The ground pin 2 of the voltage stabilizing source and the other end of the fifth resistor R6 are both grounded. The fifth resistor R6 is a sampling resistor. TL431 provides a voltage stabilizing source to ensure that the current flowing through both ends of the sampling resistor is consistent, that is, the infrared light-emitting tube passing through the sensor is consistent and is not affected by the difference in sensors. It can be understood that according to the working characteristics of the transistor, Figure 4The current flowing through the sensor is basically equal to the current flowing through the resistor R6. The current flowing through R6 is the voltage across R6 divided by the resistance of R6. Assuming that the voltage across R6 is 2.5V and the resistance of R6 is 220V, the constant current of the sensor power supply is 2.5V / 220R=11.3mA. The current flowing through the sensor is constant. Even if the sensor changes or the power supply VCC voltage changes, the purpose of constant current can be achieved.

[0051] The utility model provides a bubble detection device for a liquid pipeline, which at least comprises: a sensing module, a constant current driving module, a signal processing module and a main control module. The sensing module is used to be arranged on the liquid pipeline, the input end of the sensing module is electrically connected to the output end of the constant current driving module, and the output end of the sensing module is electrically connected to the input end of the signal processing module; the output end of the signal processing module is electrically connected to the input end of the main control module, and the input end of the constant current driving module is electrically connected to the output end of the main control module; the main control module is used to output a power control signal to the constant current driving module; the constant current driving module is used to receive the power control signal and output the constant current driving signal to the sensing module; the sensing module is used to receive the constant current driving signal, output a first sensing signal to the liquid pipeline, and receive and output a second sensing signal to the signal processing module, wherein the second sensing signal is a signal after the first sensing signal passes through the liquid pipeline; the signal processing module is used to receive the second sensing signal and output a third sensing signal to the main control module, wherein the third sensing signal is the amplified second sensing signal; the main control module is used to receive the third sensing signal and output a target judgment result, and the target judgment result is used to reflect whether there are bubbles in the liquid pipeline. Through the above device, the sensor module can achieve constant current drive, so that the sensor module can maintain a stable state. The collected signal is input into the main control after amplification processing. Different amplification factors can be set for liquid pipelines in different states, so that the above bubble detection device can be compatible with different pipelines and reagents. The circuit design of different pipeline conditions can maintain consistency, thereby achieving the purpose of cost saving and improving the distinction between bubble and liquid detection.

[0052] See also Figure 5 , Figure 5 1 is a schematic diagram of the structure of a sample analyzer in an embodiment of the utility model. The sample analyzer at least includes a liquid pipeline and a bubble detection device for the liquid pipeline as described above.

[0053] The utility model provides a structural schematic diagram of a sample analyzer, which at least includes a liquid pipeline and a bubble detection device such as the above-mentioned liquid pipeline. Through the above-mentioned bubble detection device, the sensor module can realize constant current drive, so that the sensor module can maintain a stable state, and the collected signal is input into the main control after amplification processing. Different amplification factors can be set for liquid pipelines in different states, so that the above-mentioned bubble detection device can be compatible with different pipelines and reagents, and the circuit design of different pipeline conditions can be kept consistent, so as to achieve the purpose of cost saving and improve the distinction between bubbles and liquids.

[0054] The technical features of the above embodiments may be combined arbitrarily. To make the description concise, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0055] The above-mentioned embodiments only express several implementation methods of the present application, and the descriptions thereof are relatively specific and detailed, but they cannot be understood as limiting the scope of the present application. It should be pointed out that, for a person of ordinary skill in the art, several variations and improvements can be made without departing from the concept of the present application, and these all belong to the protection scope of the present application. Therefore, the protection scope of the present application shall be subject to the attached claims.

Claims

1. A bubble detection device for a liquid pipeline, characterized in that: The bubble detection device at least comprises: a sensing module, a constant current driving module, a signal processing module and a main control module, wherein the sensing module is used to be arranged on the liquid pipeline, the input end of the sensing module is electrically connected to the output end of the constant current driving module, the output end of the sensing module is electrically connected to the input end of the signal processing module; the output end of the signal processing module is electrically connected to the input end of the main control module, and the input end of the constant current driving module is electrically connected to the output end of the main control module; The main control module is used to output a power control signal to the constant current drive module; The constant current driving module is used to receive the power control signal and output a constant current driving signal to the sensor module; The sensing module is used to receive the constant current driving signal, output a first sensing signal to the liquid pipeline, and receive and output a second sensing signal to the signal processing module, wherein the second sensing signal is a signal obtained after the first sensing signal passes through the liquid pipeline; The signal processing module is used to receive the second sensing signal and output a third sensing signal to the main control module, wherein the third sensing signal is an amplified second sensing signal; The main control module is used to receive the third sensing signal and output a target judgment result, and the target judgment result is used to reflect whether there are bubbles in the liquid pipeline.

2. The bubble detection device according to claim 1, characterized in that: The signal processing module at least includes a signal preprocessing module and a signal amplifying module which are connected in sequence, the input end of the signal processing module is the input end of the signal preprocessing module, and the output end of the signal processing module is the output end of the signal amplifying module; the output end of the sensing module is electrically connected to the input end of the signal preprocessing module; the output end of the signal amplifying module is electrically connected to the input end of the main control module; The signal preprocessing module is used to receive the second sensing signal, output the preprocessed second sensing signal, and input the preprocessed second sensing signal to the signal amplification module, wherein the preprocessing includes at least signal enhancement processing and / or signal filtering processing; The signal amplifying module is used to receive the pre-processed second sensing signal and output a third sensing signal to the main control module.

3. The bubble detection device according to claim 2, characterized in that: The bubble detection device also includes a digital potentiometer, the input end of the digital potentiometer is electrically connected to the output end of the main control module, the output end of the digital potentiometer is electrically connected to the input end of the signal amplification module, and the digital potentiometer is used to receive a gain adjustment instruction sent by the main control module and output a gain adjustment signal to the signal amplification module.

4. The bubble detection device according to claim 2, characterized in that: The sensing module includes at least one sensor among infrared, ultrasonic and capacitive sensors, and a sensor interface of the sensor. The output end of the constant current driving module is electrically connected to the power supply pin of the sensor interface, and the input end of the signal preprocessing module is electrically connected to the output pin of the sensor interface.

5. The bubble detection device according to claim 4, characterized in that: The constant current driving module at least includes a constant current driving chip, a first resistor, a second resistor, a third resistor, a fourth resistor, a diode and a MOS tube; The input end of the constant current driving module is the input pin of the constant current driving chip, the output end of the constant current driving module is one end of the first resistor, one end of the first resistor is electrically connected to the power supply pin of the sensor interface, and the input pin of the constant current driving chip is electrically connected to the output end of the main control module; The other end of the first resistor is electrically connected to one end of the second resistor, the power supply voltage end of the sensor and the drain of the MOS tube, the other end of the second resistor is electrically connected to the positive electrode of the diode, the negative electrode of the diode is grounded, the gate of the MOS tube is electrically connected to one end of the third resistor and one end of the fourth resistor, the other end of the third resistor is electrically connected to the source of the MOS tube, and the other end of the fourth resistor is electrically connected to the output pin of the constant current drive chip.

6. The bubble detection device according to claim 4, characterized in that: The signal preprocessing module at least includes an inductor, a first capacitor, a second capacitor, a third capacitor and a fourth capacitor; The input end of the signal preprocessing module is one end of the inductor, the output end of the signal preprocessing module is one end of the fourth capacitor, one end of the inductor is electrically connected to the output pin of the sensor interface, and one end of the fourth capacitor is electrically connected to the input end of the signal amplification module; The other end of the inductor is electrically connected to one end of the first capacitor, one end of the second capacitor, one end of the third capacitor and one end of the fourth capacitor, respectively, and the other end of the first capacitor, the other end of the second capacitor, the other end of the third capacitor and the other end of the fourth capacitor are all grounded.

7. The bubble detection device according to claim 4, characterized in that: The bubble detection device also includes a voltage stabilizing module, which includes at least a voltage stabilizing source and a fifth resistor. The ground pin of the sensor interface is electrically connected to one end of the fifth resistor and an input pin of the voltage stabilizing source, respectively. The power supply pin of the sensor interface is electrically connected to the output pin of the voltage stabilizing source. The ground pin of the voltage stabilizing source and the other end of the fifth resistor are both grounded.

8. The bubble detection device according to claim 1, characterized in that: The bubble detection device further comprises an ADC module, the input end of the ADC module is electrically connected to the output end of the signal processing module, and the output end of the ADC module is electrically connected to the input end of the main control module; The ADC module is used to collect the third sensing signal and output the third sensing signal after analog-to-digital conversion to the main control module; The main control module is used to receive the third sensing signal after analog-to-digital conversion and output a target judgment result.

9. The bubble detection device according to claim 8, characterized in that: The ADC module at least includes a first ADC chip and a second ADC chip, the output end of the signal processing module is electrically connected to the input end of the first ADC chip and the input end of the second ADC chip respectively, and the output end of the first ADC chip and the output end of the second ADC chip are electrically connected to the input end of the main control module respectively; The first ADC chip is used to collect the third sensing signal when the state of the liquid pipeline is stable, and output the third sensing signal after analog-to-digital conversion to the main control module; The second ADC chip is used to collect the third sensing signal when the state of the liquid pipeline is unstable, and output the third sensing signal after analog-to-digital conversion to the main control module. The signal collection accuracy and analog-to-digital conversion speed of the first ADC chip are both lower than those of the second ADC chip.

10. A sample analyzer, characterized in that: The sample analyzer at least comprises a liquid pipeline and a bubble detection device for the liquid pipeline according to any one of claims 1-9.

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