Solid-liquid separation equipment for heparin sodium processing salt hydrolysate

Abstract

The utility model discloses heparin sodium processing salt hydrolysate solid-liquid separation equipment, which belongs to the technical field of solid-liquid separation and comprises a base, an ethanol box is fixedly connected to the upper surface of the base, a centrifugal kettle is rotatably connected to the inside of the ethanol box, and two groups of fixing blocks are fixedly connected to the upper surface of the ethanol box. The side faces, close to each other, of the two fixing blocks are jointly and fixedly connected with a supporting frame, the inner bottom wall of the supporting frame is fixedly connected with two limiting springs, and the top ends of the two limiting springs are jointly and fixedly connected with a vibration frame. According to the solid-liquid separation equipment for the heparin sodium processing salt hydrolysate, through cooperation of a plurality of assemblies, the filter screen does not need to be driven to shake through collision, the service life of the filter screen is effectively prolonged, the function of conveniently disassembling and cleaning the filter screen is achieved, the filter screen can be conveniently disassembled and cleaned when the filter screen is blocked due to long-time use, and the service life of the filter screen is prolonged. The next use effect is effectively improved, and the effect of improving the applicability of the heparin sodium salt hydrolysate solid-liquid separation equipment is achieved.

Description

Technical Field

[0001] The present application belongs to the technical field of solid-liquid separation, and in particular relates to a solid-liquid separation device for heparin sodium processing salt hydrolysis liquid. Background Art

[0002] In the current precipitation process of sodium heparin preparation, after the sodium heparin semi-finished product is formed in the precipitation tank, the sodium heparin solution and the liquid on the upper layer of the solution must be separated to obtain bulk sodium heparin in the later processing. The existing traditional separation process equipment uses a precipitation tank that can accommodate a large amount of solution. A straw is placed in the tank cavity to extract the waste water on the upper layer of the sodium heparin solution to obtain the sodium heparin solution. However, when the straw extracts the waste water on the upper layer of the solution, part of the sodium heparin solution is often also sucked out of the tank body.

[0003] The utility model with the existing authorization announcement number CN218653392U discloses a heparin sodium salt hydrolysis solid-liquid separation device, including a base, an ethanol tank, a centrifugal kettle, a control box, a solenoid valve, and a rotating motor. The upper surface of the base is fixedly connected to a box body through four symmetrically arranged fixing columns.

[0004] The above technical solution can achieve the effect that even after long-term use, the material in the reactor will not accumulate and effective mixing and stirring will not be possible. Even after long-term use, the material will not accumulate on the filter screen, affecting the filtering effect of the filter screen. However, the above technical solution, because the cam continuously hits the abutment plate for a long time, causing the filter screen to shake, seriously increases the wear of the abutment plate, thereby reducing the service life of the abutment plate and the filter screen, and does not have the function of convenient disassembly and cleaning of the filter screen. After the filter screen is used for a long time, it is easy to cause blockage, and it is difficult to disassemble and clean it, which affects the effect of the next use, reducing the applicability of the heparin sodium salt hydrolyzate solid-liquid separation equipment.

[0005] Therefore, we propose a sodium heparin processing salt solution solid-liquid separation equipment to solve the above problems. Utility Model Content

[0006] The purpose of the present application is to solve the problems in the prior art that the filter screen is excessively worn and cannot be conveniently disassembled and cleaned, and to propose a solid-liquid separation device for heparin sodium processing salt hydrolysis liquid.

[0007] In order to achieve the above purpose, the utility model adopts the following technical solutions:

[0008] A sodium heparin processing salt hydrolysis liquid solid-liquid separation device comprises a base, an ethanol box is fixedly connected to the upper surface of the base, a centrifugal kettle is rotatably connected to the inside of the ethanol box, two groups of fixed blocks are fixedly connected to the upper surface of the ethanol box, a side surface of the two groups of fixed blocks close to each other is fixedly connected to a support frame, two groups of limit springs are fixedly connected to the inner bottom wall of the support frame, the top ends of the two groups of limit springs are fixedly connected to a vibration frame, a vibration motor is fixedly connected to the right side of the vibration frame, an auxiliary frame is arranged inside the vibration frame, a filter screen is clamped inside the auxiliary frame, two auxiliary handles are fixedly connected to the upper surface of the auxiliary frame, a limit rod is slidably connected to the inside of the vibration frame and the auxiliary frame, an auxiliary spring is sleeved on the outside of the limit rod, the right end of the auxiliary spring is fixedly connected to the inner side wall of the limit rod, the left end of the auxiliary spring is fixedly connected to the inner side wall of the vibration frame, and the left end of the limit rod is fixedly connected to a transmission handle.

[0009] Preferably, the inner bottom wall of the ethanol tank is fixedly connected to a servo motor, the output end of the servo motor power is fixedly connected to a rotating rod, and the top end of the rotating rod is fixedly connected to the outer surface of the centrifugal kettle.

[0010] Preferably, the outer surface of the servo motor is covered with a waterproof shell, and the bottom surface of the waterproof shell is fixedly connected to the inner bottom wall of the ethanol tank.

[0011] Preferably, the upper surface of the base is fixedly connected to two supporting legs, and the upper surfaces of the two supporting legs are commonly fixedly connected to a waste water tank.

[0012] Preferably, a reactor is fixedly connected to the inner wall of the wastewater tank, and a feed inlet is fixedly connected to the upper surface of the reactor.

[0013] Preferably, the outer surface of the reactor is fixedly connected with two groups of drain pipes, and the ends of the two groups of drain pipes that are away from each other pass through the reactor and extend to the inside of the wastewater tank. The outer surface of each group of drain pipes is fixedly connected with a first solenoid valve.

[0014] Preferably, a rotating motor is fixedly connected to the upper surface of the reactor, a stirring blade is fixedly connected to the output end of the rotating motor power, and the bottom end of the stirring blade penetrates the reactor and extends to the interior of the reactor.

[0015] Preferably, the bottom end of the reactor is fixedly connected to a discharge port, and the outer surface of the discharge port is fixedly connected to a second solenoid valve.

[0016] In summary, the technical effects and advantages of this application are:

[0017] 1. By setting a fixed block, a support frame, a limit spring, a vibration frame, an auxiliary frame, a filter and a vibration motor, the vibration force generated by the vibration motor can be used to drive the auxiliary frame to vibrate, so that the filter can vibrate at the same time, effectively avoiding the situation where the material on the filter is accumulated and affects the filtering effect of the filter. At the same time, it can also reduce the wear speed of the filter during use. The limit spring can limit the vibration amplitude of the filter to avoid the possibility of material leakage due to excessive vibration amplitude, so that the filter does not need to be driven to vibrate by collision, which effectively increases the service life of the filter;

[0018] 2. By setting a limit rod, an auxiliary spring and a transmission handle, the transmission handle can be used to drive the limit rod to move, thereby removing the limit rod from the inside of the auxiliary frame, so that the auxiliary frame can be in an unobstructed state, and the auxiliary frame and the filter can be conveniently disassembled and cleaned. At the same time, the auxiliary spring can enable the limit rod to achieve the function of resetting, thereby increasing the convenience of installing the auxiliary frame and improving the stability of the auxiliary frame when limiting the position, thereby realizing the function of convenient disassembly and cleaning of the filter. When the filter is blocked due to long-term use, it can be conveniently disassembled and cleaned, thereby effectively increasing the effect of the next use, thereby improving the applicability of the heparin sodium salt hydrolysis solid-liquid separation equipment. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 It is a three-dimensional structural diagram of the base of the utility model;

[0020] Figure 2 This is a schematic diagram of the structure of the ethanol tank of the utility model in a cutaway perspective view;

[0021] Figure 3 This is a schematic diagram of the structure of the vibration frame of the utility model in a cutaway perspective view;

[0022] Figure 4 It is a schematic diagram of the three-dimensional structure of the wastewater tank of the utility model in cross section.

[0023] In the figure: 1. base; 2. ethanol tank; 3. centrifugal kettle; 4. fixing block; 5. support frame; 6. limit spring; 7. vibration frame; 8. vibration motor; 9. auxiliary frame; 10. filter screen; 11. auxiliary handle; 12. limit rod; 13. auxiliary spring; 14. transmission handle; 15. servo motor; 16. rotating rod; 17. waterproof shell; 18. support leg; 19. waste water tank; 20. reactor; 21. feed port; 22. drain pipe; 23. first solenoid valve; 24. rotating motor; 25. stirring blade; 26. discharge port; 27. second solenoid valve. DETAILED DESCRIPTION

[0024] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all of the embodiments.

[0025] Reference Figure 1-4 A sodium heparin processing salt hydrolysis liquid solid-liquid separation device comprises a base 1, an ethanol box 2 is fixedly connected to the upper surface of the base 1, a centrifugal kettle 3 is rotatably connected inside the ethanol box 2, a servo motor 15 is fixedly connected to the inner bottom wall of the ethanol box 2, a rotating rod 16 is fixedly connected to the output end of the servo motor 15 power, the top of the rotating rod 16 is fixedly connected to the outer surface of the centrifugal kettle 3, the power generated by the servo motor 15 is used to drive the rotating rod 16 to rotate, and then the centrifugal kettle 3 is rotated, and the sodium heparin solution and small particle mucosal substances are separated through multiple centrifugal holes inside the centrifugal kettle 3 by relying on the rotation of the centrifugal kettle 3.

[0026] The outer surface of the servo motor 15 is covered with a waterproof shell 17, and the bottom surface of the waterproof shell 17 is fixedly connected to the inner bottom wall of the ethanol tank 2. The waterproof shell 17 can ensure the stability of the servo motor 15 during operation, prevent ethanol from entering the servo motor 15 and causing damage to it, increase the protection of the servo motor 15, and improve the service life of the servo motor 15.

[0027] Two groups of fixing blocks 4 are fixedly connected to the upper surface of the ethanol tank 2, and a supporting frame 5 is fixedly connected to one side of the two groups of fixing blocks 4 close to each other, and two groups of limiting springs 6 are fixedly connected to the inner bottom wall of the supporting frame 5, and the top ends of the two groups of limiting springs 6 are fixedly connected to a vibration frame 7, and a vibration motor 8 is fixedly connected to the right side of the vibration frame 7. Two supporting legs 18 are fixedly connected to the upper surface of the base 1, and a waste water tank 19 is fixedly connected to the upper surfaces of the two supporting legs 18. Through the cooperation of the supporting legs 18 and the waste water tank 19, the waste water tank 19 has the function of collecting and storing waste water, and the supporting legs 18 can support the waste water tank 19 to prevent the waste water tank 19 from falling.

[0028] The inner wall of the wastewater tank 19 is fixedly connected with a reactor 20, and the upper surface of the reactor 20 is fixedly connected with a feed port 21. The reactor 20 can effectively assist in the process of sodium heparin separation. At the same time, the feed port 21 can improve the convenience of adding materials into the reactor 20, thereby increasing the convenience of the device.

[0029] An auxiliary frame 9 is provided inside the vibration frame 7, and a filter screen 10 is clamped inside the auxiliary frame 9. Two auxiliary handles 11 are fixedly connected to the upper surface of the auxiliary frame 9. The interior of the vibration frame 7 and the auxiliary frame 9 are slidably connected with a limit rod 12. The outer surface of the reactor 20 is fixedly connected with two groups of drain pipes 22. The ends of the two groups of drain pipes 22 that are away from each other both penetrate the reactor 20 and extend to the inside of the waste water tank 19. The outer surface of each group of drain pipes 22 is fixedly connected with a first solenoid valve 23, which can use drain pipes 22 of different heights to discharge the waste water inside the reactor 20 into the waste water tank 19 in batches. At the same time, the first solenoid valve 23 can control the closing state of the drain pipe 22 to improve convenience during use.

[0030] An auxiliary spring 13 is sleeved on the outside of the limiting rod 12, the right end of the auxiliary spring 13 is fixedly connected to the inner wall of the limiting rod 12, the left end of the auxiliary spring 13 is fixedly connected to the inner wall of the vibration frame 7, the left end of the limiting rod 12 is fixedly connected to the transmission handle 14, the upper surface of the reactor 20 is fixedly connected to a rotating motor 24, the output end of the power of the rotating motor 24 is fixedly connected to a stirring blade 25, the bottom end of the stirring blade 25 penetrates the reactor 20 and extends to the inside of the reactor 20, the power generated by the rotating motor 24 is used to drive the stirring blade 25 to rotate inside the reactor 20, so that the materials inside the reactor 20 are fully mixed, effectively increasing the effect of solid-liquid separation of heparin sodium.

[0031] The bottom end of the reactor 20 is fixedly connected to a discharge port 26, and the outer surface of the discharge port 26 is fixedly connected to a second solenoid valve 27. The discharge port 26 can be used to discharge the fully mixed material inside the reactor 20 to the surface of the filter 10. At the same time, the second solenoid valve 27 can control the closing state of the discharge port 26.

[0032] The working principle of the utility model is as follows: when in use, firstly, the vibration motor 8, the servo motor 15, the rotating motor 24, the first solenoid valve 23 and the second solenoid valve 27 are powered on, and the material is added into the reactor 20 through the feed port 21, and then the servo motor 15 is started, so that the stirring blade 25 rotates inside the reactor 20 to fully mix the material, and then the waste water inside the reactor 20 is discharged into the waste water tank 19 one by one through the cooperation of the drain pipe 22 and the first solenoid valve 23, so as to retain the mucosal floccules and the heparin sodium solution, and then the discharge port 26 is opened by the second solenoid valve 27, and the vibration motor 8 is started, so that the material retained inside the reactor 20 falls onto the surface of the filter screen 10, and the filter screen 10 is used to separate the internal bulk materials, and the particulate matter falls into the inside of the centrifugal reactor 3, and at the same time, the vibration frame 7, the auxiliary frame 9 and the filter screen 10 are driven by the vibration motor 8 to enter The auxiliary frame 9 and the filter screen 10 are vibrated, which can effectively avoid the accumulation of materials above the filter screen 10 and improve the filtering effect. The limit spring 6 can limit the vibration amplitude of the auxiliary frame 9 and the filter screen 10, and then the rotating motor 24 is started to drive the centrifugal kettle 3 to rotate, so as to make the internal materials do centrifugal movement, so that the sodium heparin solution is discharged from the centrifugal hole into the ethanol tank 2, and the sodium heparin is precipitated by ethanol. When the filter screen 10 needs to be disassembled and cleaned, the transmission handle 14 is pulled, and the limit rod 12 is moved out from the inside of the auxiliary frame 9, so that the auxiliary frame 9 is in an unobstructed state. At this time, the auxiliary handle 11 can be lifted to take out and clean the auxiliary frame 9 and the filter screen 10 to prevent the filter screen 10 from being blocked and affecting the next use. The auxiliary spring 13 can make the limit rod 12 have a reset effect, which improves the convenience of installing the auxiliary frame 9 and increases the applicability of the sodium heparin salt hydrolysis liquid-solid separation equipment.

[0033] In the description of the present invention, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise" and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the referred device or element must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation on the present invention.

[0034] In addition, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" and "second" may explicitly or implicitly include one or more of the features. In the description of the present utility model, the meaning of "plurality" is two or more, unless otherwise clearly and specifically defined.

[0035] The above description is only a preferred specific implementation manner of the present invention, but the protection scope of the present invention is not limited thereto. Any technician familiar with the technical field can make equivalent replacements or changes within the technical scope disclosed by the present invention according to the technical scheme and the utility model concept of the present invention, which should be covered by the protection scope of the present invention.

Claims

1. A heparin sodium processing salt solution solid-liquid separation device, comprising a base (1), characterized in that: The upper surface of the base (1) is fixedly connected to an ethanol box (2), the interior of the ethanol box (2) is rotatably connected to a centrifugal kettle (3), the upper surface of the ethanol box (2) is fixedly connected to two groups of fixed blocks (4), the side surfaces of the two groups of fixed blocks (4) close to each other are fixedly connected to a support frame (5), the inner bottom wall of the support frame (5) is fixedly connected to two groups of limit springs (6), the top ends of the two groups of limit springs (6) are fixedly connected to a vibration frame (7), the right side surface of the vibration frame (7) is fixedly connected to a vibration motor (8), and the interior of the vibration frame (7) is provided with a An auxiliary frame (9), wherein a filter screen (10) is clamped inside the auxiliary frame (9), two auxiliary handles (11) are fixedly connected to the upper surface of the auxiliary frame (9), a limit rod (12) is slidably connected to the inside of the vibration frame (7) and the auxiliary frame (9), an auxiliary spring (13) is sleeved on the outside of the limit rod (12), the right end of the auxiliary spring (13) is fixedly connected to the inner side wall of the limit rod (12), the left end of the auxiliary spring (13) is fixedly connected to the inner side wall of the vibration frame (7), and the left end of the limit rod (12) is fixedly connected to a transmission handle (14).

2. The heparin sodium processing salt hydrolyzate solid-liquid separation equipment according to claim 1, characterized in that: The inner bottom wall of the ethanol tank (2) is fixedly connected to a servo motor (15), the power output end of the servo motor (15) is fixedly connected to a rotating rod (16), and the top end of the rotating rod (16) is fixedly connected to the outer surface of the centrifugal kettle (3).

3. The heparin sodium processing salt solution solid-liquid separation equipment according to claim 2, characterized in that: The outer surface of the servo motor (15) is covered with a waterproof housing (17), and the bottom surface of the waterproof housing (17) is fixedly connected to the inner bottom wall of the ethanol tank (2).

4. The heparin sodium processing salt hydrolyzate solid-liquid separation equipment according to claim 1, characterized in that: Two support legs (18) are fixedly connected to the upper surface of the base (1); and a waste water tank (19) is fixedly connected to the upper surfaces of the two support legs (18).

5. The heparin sodium processing salt hydrolyzate solid-liquid separation equipment according to claim 4, characterized in that: The inner wall of the waste water tank (19) is fixedly connected to a reaction kettle (20), and the upper surface of the reaction kettle (20) is fixedly connected to a feed inlet (21).

6. The heparin sodium processing salt hydrolyzate solid-liquid separation equipment according to claim 5, characterized in that: The outer surface of the reactor (20) is fixedly connected to two groups of drainage pipes (22), and ends of the two groups of drainage pipes (22) that are away from each other penetrate the reactor (20) and extend to the interior of the waste water tank (19), and the outer surface of each group of drainage pipes (22) is fixedly connected to a first solenoid valve (23).

7. The heparin sodium processing salt hydrolyzate solid-liquid separation equipment according to claim 5, characterized in that: A rotating motor (24) is fixedly connected to the upper surface of the reaction kettle (20), and a stirring blade (25) is fixedly connected to the output end of the power of the rotating motor (24), and the bottom end of the stirring blade (25) penetrates the reaction kettle (20) and extends into the interior of the reaction kettle (20).

8. The heparin sodium processing salt hydrolyzate solid-liquid separation equipment according to claim 5, characterized in that: The bottom end of the reaction kettle (20) is fixedly connected to a discharge port (26), and the outer surface of the discharge port (26) is fixedly connected to a second solenoid valve (27).

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