Automatic sample diluting device
By designing an automatic sample dilution device and automatically diluting and cleaning using sampling and cleaning mechanisms, the problems of low sample dilution efficiency and sample contamination in the prior art are solved, and detection efficiency is improved and cost savings are saved.
Patent Information
- Application Number
- CN202421250880.3
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-06-03
- Publication Date
- 2025-04-18
- Estimated Expiration
- 2034-06-03
AI Technical Summary
Existing sample dilution methods are inefficient and difficult to completely clean, resulting in sample contamination.
An automatic sample dilution device is designed, including a sampling mechanism and a cleaning mechanism. The sampling mechanism realizes the lifting and lowering movement of the sampling arm through the ball screw nut pair driven by a stepper motor. The sampling needle can be extended into the sampling test tube and connected to the cleaning sleeve to achieve automatic dilution and cleaning.
Automatic dilution and cleaning of samples is realized, manual operation steps are reduced, detection efficiency is improved, sample contamination is avoided, and consumable costs are saved.
Smart Images

Figure CN222774372U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to a detection technology, in particular to an automatic sample dilution device. Background Art
[0002] Sample dilution is a common experimental operation method that can reduce the concentration of the test solution in the experiment and control its concentration range within the appropriate measurement range in order to obtain more accurate results.
[0003] Currently, in analytical chemistry and medical testing applications, sample dilution is performed by manually adding diluent solution to aliquot a stock solution using a pipette or pipette. This continuous dilution process is subject to significant manual errors and is time-consuming. Furthermore, existing dilution methods cannot effectively clean the pipette tip during operation, leading to sample contamination. Utility Model Content
[0004] The utility model provides an automatic sample dilution device, which aims to solve the problem that the sample dilution means in the prior art are inefficient and difficult to completely clean during the sampling process, thus causing sample contamination.
[0005] The automatic sample dilution device that can solve the above technical problems includes a sampling mechanism and a cleaning mechanism. The difference is that:
[0006] 1. The cleaning mechanism includes a cleaning sleeve, and a cleaning inlet pipe and a cleaning outlet pipe are connected on the side of the cleaning sleeve.
[0007] 2. The sampling mechanism includes a sampling arm, which is driven by a ball screw nut pair driven by a stepper motor I to perform an ascending and descending motion along the left and right linear guide pairs. The overhanging end of the sampling arm is provided with a sampling needle that penetrates downward through the cleaning sleeve and is aligned with the sampling test tube. The sampling needle is a double-lumen needle tube. At the top of the sampling needle, one lumen is connected to the sampling tube, and the other lumen is connected to the sampling test tube.
[0008] 3. At the defined position where the sampling arm descends, the sampling needle extends into the sampling tube and the lower end of the sampling needle does not touch the bottom of the sampling tube.
[0009] 4. At the limited position where the sampling arm rises, the sampling needle exits the sampling tube and the needle tip of the sampling needle is in the cleaning sleeve.
[0010] Furthermore, a structure of the ball screw nut pair includes a screw and a ball screw nut that cooperate with each other, the ball screw nut is arranged in the sampling arm, the upper shaft end of the screw is connected to the rotating shaft of the stepper motor I, and the stepper motor I is installed on the top of the sampling rack.
[0011] Furthermore, a structure of each linear guide pair includes a guide rod and ball linear bearings that cooperate with each other. The left and right ball linear bearings are arranged in the sampling arm on both sides of the ball screw nut, and the left and right guide rods are installed between the top and bottom of the sampling rack.
[0012] Furthermore, an upper photoelectric sensor and a lower photoelectric sensor installed on the side of the sampling rack are respectively provided at the upper and lower limited positions, and a photoelectric sensor baffle I is provided on the sampling arm which can sense the upper and lower photoelectric sensors respectively.
[0013] Conventionally, the technical solution of the present invention also includes a turntable mechanism, and a plurality of sampling test tubes are arranged circumferentially in the turntable of the turntable mechanism. The turntable rotates under the drive of a synchronous pulley transmission pair driven by a stepper motor II to rotate each sampling test tube to a sampling position.
[0014] Beneficial effects of the utility model:
[0015] 1. The utility model can cooperate with the detection instrument to perform sample dilution processing, such as automatic test tube sampling, automatic liquid addition and dilution, automatic detection, and cleaning of the sampling needle and liquid path after completion. Especially when the number of samples is large, it can effectively reduce manual steps and improve the detection efficiency of the instrument.
[0016] 2. In the structure of the present invention, the sampling mechanism, the cleaning mechanism and the turntable mechanism cooperate with each other to realize cyclical, precise and automatic sampling, dilution and cleaning operations.
[0017] 3. The utility model eliminates the need for disposable sampling nozzle consumables, effectively saving costs and being energy-efficient and environmentally friendly. BRIEF DESCRIPTION OF THE DRAWINGS
[0018] Figure 1 This is an axonometric drawing of an embodiment of the present invention.
[0019] Figure 2 for Figure 1 Exploded view of an embodiment.
[0020] Figure 3 for Figure 1 Axonometric view of the sampling mechanism from a first perspective in an embodiment.
[0021] Figure 4 for Figure 1 Axonometric view of the sampling mechanism from a second perspective in an embodiment.
[0022] Figure number identification: 1. Sampling arm; 2. Stepper motor I; 3. Sampling needle; 4. Sampling tube; 5. Sampling test tube; 6. Cleaning sleeve; 7. Cleaning inlet tube; 8. Cleaning outlet tube; 9. Sampling test tube; 10. Screw; 11. Ball screw nut; 12. Guide rod; 13. Ball linear bearing; 14. Sampling rack; 15. Upper photoelectric sensor; 16. Lower photoelectric sensor; 17. Photoelectric sensor baffle I; 18. Turntable; 19. Stepper motor II; 20. Synchronous pulley drive pair; 21. Base; 22. Cleaning rack; 23. Motor base; 24. Photoelectric sensor baffle II; 25. Zero position photoelectric sensor. DETAILED DESCRIPTION
[0023] The technical solution of the present utility model will be further described below with reference to the embodiments shown in the accompanying drawings.
[0024] The automatic sample dilution device of the present invention comprises a sampling mechanism, a cleaning mechanism and a turntable mechanism arranged on a base 21, such as Figure 1 、 Figure 2 shown.
[0025] The sampling mechanism is arranged on the rear left side of the base 21, including a sampling rack 14 fixed on the base 21, the sampling rack 14 includes a top plate and a bottom plate and a side plate connected to the back side of the top plate and the bottom plate, a stepper motor Ⅰ2 is installed on the top plate, a sampling arm 1 is provided between the top plate and the bottom plate, and a ball screw nut pair is provided between the top plate and the bottom plate in correspondence with the stepper motor Ⅰ2, the ball screw nut pair includes a screw rod 10 and a ball screw nut 11 that are screwed together, the upper and lower ends of the screw rod 10 are respectively installed on the top plate and the bottom plate through bearings, the screw rod 1 0 is connected to the downward rotating shaft of the stepper motor I2 through the top plate, and the ball screw nut 11 is arranged inside the sampling arm 1. The stepper motor I2 drives the sampling arm 1 to rise and fall between the top plate and the bottom plate along the left and right linear guide pairs through the ball screw nut pair; each linear guide pair includes a guide rod 12 and a ball linear bearing 13 that are slidably matched. The left and right guide rods 12 are vertically arranged between the top plate and the bottom plate on both sides of the screw rod 10, and the left and right ball linear bearings 13 are arranged inside the sampling arm 1 on both sides of the ball screw nut 11. Figure 1 、 Figure 2 、 Figure 3 、 Figure 4 shown.
[0026] The right end of the sampling arm 1 is a cantilever, and a sampling needle 3 is installed vertically downward in the right end hole of the cantilever. The sampling needle 3 is a double-lumen needle tube, and the position corresponding to the downward position of the sampling needle 3 is the sampling position. At the top of the sampling needle 3, one lumen is connected to the sampling tube 4 above the sampling arm 1, and the other lumen is connected to the sampling test tube 5 above the sampling arm 1; a photoelectric sensor baffle Ⅰ17 extending backward is installed on the cantilever, and an upper photoelectric sensor 15 and a lower photoelectric sensor 16 are provided on the side panel of the sampling frame 14 corresponding to the photoelectric sensor baffle Ⅰ17. When the sampling arm 1 rises and falls, the photoelectric sensor baffle Ⅰ17 respectively senses the upper and lower photoelectric sensors 15 and 16 to limit the rising and falling height positions of the sampling arm 1, as shown in FIG. Figure 1 、 Figure 2 、 Figure 3 、 Figure 4 shown.
[0027] The cleaning mechanism includes a cleaning sleeve 6, and the upper and lower interfaces on the side of the cleaning sleeve 6 are respectively connected to the cleaning introduction pipe 7 and the cleaning discharge pipe 8. The sampling needle 3 passes through the cleaning sleeve 6, and the cleaning sleeve 6 is installed on the side plate of the sampling frame 14 through the cleaning frame 22. The installation height of the cleaning sleeve 6 corresponds to the upper photoelectric sensor 15, that is, when the sampling arm 1 stops at the limited position of the rise, the lower end needle tip of the sampling needle 3 is inside the cleaning sleeve 6, as shown in FIG. Figure 1 、 Figure 2 、 Figure 3 、 Figure 4 shown.
[0028] The turntable mechanism is arranged on the right side of the sampling mechanism. The I-shaped turntable 18 of the turntable mechanism is mounted on the base 21 through a rotating shaft. The front side of the turntable 18 is provided with a stepper motor II 19 mounted on the base 21 through a motor seat 23. The stepper motor II 19 is connected to the rotating shaft through a synchronous belt pulley transmission pair 20. The synchronous belt pulley transmission pair 20 includes a driving pulley and a driven pulley connected by a synchronous belt. The driving pulley is mounted on the downward rotating shaft of the stepper motor II 19, and the driven pulley is mounted on the rotating shaft between the turntable 18 and the base 21. The circumference of the turntable 18 is evenly distributed with upper and lower pairs of The insertion holes of the upper and lower insertion holes can be placed in a corresponding sampling test tube 9. The stepping motor II 19 drives the turntable 18 to perform a cyclic rotation through the synchronous pulley transmission pair 20 to rotate the sampling test tube 9 to the sampling position; the base 21 is also equipped with a zero position photoelectric sensor 25, and a photoelectric sensor baffle II 24 is provided on the lower part of the turntable 18 corresponding to the zero position photoelectric sensor 25. Each time the turntable 18 rotates one circle, the photoelectric sensor baffle II 24 triggers the zero position photoelectric sensor 25 once, thereby calibrating the origin position of each rotation of the turntable 18, thereby ensuring that each sampling test tube 9 reaches the sampling position accurately. Figure 1 、 Figure 2 shown.
[0029] The automatic sample dilution device of the present invention operates as follows:
[0030] 1. First, calibrate the starting position of the turntable 18 , and then place N sampling tubes 9 containing samples into the corresponding insertion holes on the turntable 18 .
[0031] 2. Stepper motor II 19 is started, and the rotating turntable 18 moves the first sampling tube 9 to the sampling position.
[0032] 3. The stepper motor I2 is started, and the sampling arm 1 drives the sampling needle 3 to descend (extend out of the cleaning sleeve 6) and extend into the sampling tube 9 until the photoelectric sensor baffle I17 senses the lower photoelectric sensor 16 and stops. At this time, the needle tip of the sampling needle 3 does not touch the bottom of the sampling tube 9.
[0033] 4. Perform sampling and dilution work through the sampling tube 4, and perform sampling and testing work through the sampling test tube 5.
[0034] 5. After the dilution and sampling tests are completed, the stepper motor I2 is started, and the sampling arm 1 drives the sampling needle 3 to rise and move out of the sampling tube 9 until the photoelectric sensor baffle I17 senses the upper photoelectric sensor 15 and stops. At this time, the needle tip of the sampling needle 3 returns to the inside of the cleaning sleeve 6.
[0035] 6. Inject cleaning liquid into the cleaning sleeve 6 through the cleaning introduction tube 7 to clean the needle tip surface and the needle hole of the sampling needle 3, and quickly draw the cleaning liquid out of the cleaning sleeve 6 through the cleaning discharge tube 8 to complete the cleaning process.
[0036] 7. The stepper motor II 19 is started, and the rotating turntable 18 moves the next sampling tube 9 to the sampling position, and the first sampling tube 9 that has completed dilution is moved out of the sampling position.
[0037] 8. Repeat steps 3 to 7 continuously to automatically complete the dilution operation of the samples in all the sampling test tubes 9.
Claims
1. A sample automatic dilution device, comprising a sampling mechanism and a cleaning mechanism, characterized in that: The cleaning mechanism comprises a cleaning sleeve (6), and a cleaning inlet pipe (7) and a cleaning outlet pipe (8) are connected on the side of the cleaning sleeve (6); The sampling mechanism comprises a sampling arm (1), and the sampling arm (1) is driven by a ball screw nut pair driven by a stepping motor I (2) to perform an ascending and descending motion along left and right linear guide pairs. A sampling needle (3) is provided at the cantilevered end of the sampling arm (1), which penetrates downward through a cleaning sleeve (6) and is aligned with a sampling test tube (9). The sampling needle (3) is a double-lumen needle tube, and at the top of the sampling needle (3), one lumen is connected to the sampling tube (4), and the other lumen is connected to the sampling test tube (5); At a limited position where the sampling arm (1) is lowered, the sampling needle (3) extends into the sampling test tube (9) and the lower needle tip of the sampling needle (3) does not touch the bottom of the sampling test tube (9); At the limited position where the sampling arm (1) rises, the sampling needle (3) exits the sampling test tube (9) and the needle tip of the sampling needle (3) is located in the cleaning sleeve (6).
2. The automatic sample dilution device according to claim 1, characterized in that: The ball screw nut pair comprises a screw (10) and a ball screw nut (11) which cooperate with each other. The ball screw nut (11) is arranged in the sampling arm (1). The upper shaft end of the screw (10) is connected to the rotating shaft of the stepper motor I (2). The stepper motor I (2) is installed on the top of the sampling frame (14).
3. The automatic sample dilution device according to claim 2, characterized in that: Each linear guide pair comprises a guide rod (12) and a ball linear bearing (13) that cooperate with each other. The left and right ball linear bearings (13) are arranged in the sampling arm (1) on both sides of the ball screw nut (11). The left and right guide rods (12) are installed between the top and the bottom of the sampling frame (14).
4. The automatic sample dilution device according to claim 2, characterized in that: An upper photoelectric sensor (15) and a lower photoelectric sensor (16) mounted on the side of the sampling frame (14) are respectively provided at the upper and lower limited positions, and a photoelectric sensor baffle I (17) capable of induction with the upper photoelectric sensor (15) and the lower photoelectric sensor (16) is respectively provided on the sampling arm (1).
5. The automatic sample dilution device according to any one of claims 1 to 4, characterized in that: The invention also comprises a turntable mechanism, wherein a plurality of sampling test tubes (9) are evenly arranged on a turntable (18) of the turntable mechanism. The turntable (18) is driven by a synchronous belt wheel transmission pair (20) driven by a stepping motor II (19) to perform a rotary motion to rotate each sampling test tube (9) to a sampling position.
Citation Information
Cited By
Automatic sample diluting device and method
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