Magnetic bead mixer

By designing a magnetic bead mixer containing magnetic units and mixing units, the problem of difficult to mix magnetic beads in the prior art is solved, uniform mixing of reagents is achieved, time and manpower are reduced for manual operation, and the accuracy of experimental results is ensured.

CN222805060UActive Publication Date: 2025-04-29XIAN JINYU MEDICAL INSPECTION OFFICE CO LTD
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Patent Information

Application Number
CN202420919643.5
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-04-29
Publication Date
2025-04-29
Estimated Expiration
2034-04-29

AI Technical Summary

Technical Problem

It is difficult to achieve sufficient mixing of magnetic bead mixers in existing medical testing equipment, resulting in deviations in experimental results, and manual operation takes time and labor.

Method used

A magnetic bead mixer is designed, including an outer shell, a mixing unit, a clamping unit, a magnetic unit and a control unit. The precipitated magnetic beads are adsorbed by the magnetic unit, and the mixing unit drives the test tube to vibrate to achieve uniform mixing of the magnetic beads.

Benefits of technology

The full mixing of magnetic beads is achieved, which reduces the time and manpower of manual operation, ensures the effect of the reagent, and avoids deviations in experimental results.

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Abstract

The utility model provides a magnetic bead mixer, which belongs to the technical field of medical detection equipment, and comprises an outer shell and a mixing unit, the upper surface of the mixing unit is connected with the bottom of the outer shell, the outer shell is vertically provided with a limiting through hole penetrating through the circle center of the outer shell, a test tube is placed in the outer shell, and the test tube is connected with the lower surface of the mixing unit. A clamping unit is arranged at the top of the outer shell, the clamping unit is used for fixing a test tube, the magnetic unit is arranged in the outer shell, the problems of long time consumption and poor effect of manual uniform mixing are solved, the effect of a reagent is ensured, and deviation caused by insufficient uniform mixing of magnetic beads is avoided.
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Description

Technical Field

[0001] The utility model belongs to the technical field of medical detection equipment, and specifically relates to a magnetic bead mixer. Background Art

[0002] Reagent mixing is an important breakthrough in the field of medical testing technology and an important component of the stability of chemiluminescence analyzers. The quality of magnetic bead mixing will directly affect the experimental results. At present, all instruments come with magnetic bead mixers.

[0003] At present, the manufacturer's reagents are difficult to achieve a fully mixed state on the fully automatic analyzer, and manual operation is required to achieve a fully mixed state before the machine is operated. Manual operation is time-consuming and labor-intensive, and the poor effect can easily lead to deviations in the results. Therefore, a magnetic bead mixer is needed to solve this problem. Utility Model Content

[0004] The utility model aims to provide a magnetic bead mixer.

[0005] To achieve the above-mentioned purpose, the utility model provides a magnetic bead mixer, including an outer shell and a mixing unit, the upper surface of the mixing unit is connected to the bottom of the outer shell, a limiting through hole is vertically opened on the outer shell and passes through the center of the circle, a test tube is placed in the outer shell, a clamping unit is arranged on the top of the outer shell, the clamping unit is used to fix the test tube, and also includes a magnetic unit, which is arranged in the outer shell.

[0006] Furthermore, the clamping unit includes an elastic member, a soft pad, and two relatively arranged clamping members, wherein the elastic member is used to adjust the tightness of the two relatively arranged clamping members so as to restrict the test tube between the two clamping members; the soft pad is arranged on the inner side of the clamping member so as to clamp the soft pad on the outer periphery of the test tube.

[0007] Furthermore, the clamping piece is arc-shaped, and a circle is formed between the two clamping pieces.

[0008] Furthermore, the elastic member is a spring to generate opposite pulling forces on the two clamping members.

[0009] Furthermore, it also includes a control unit, which is arranged on the mixing unit and is electrically connected to the mixing unit.

[0010] Furthermore, it also includes a power supply unit, which is arranged in the mixing unit and is electrically connected to the mixing unit and the control unit respectively.

[0011] Furthermore, the outer shell is a double-layer structure, a placement cavity is formed between the double-layer structure of the outer shell, and the magnetic unit is arranged in the placement cavity.

[0012] Furthermore, the magnetic unit is an electromagnet, and the electromagnet is electrically connected to the control unit so that the control unit can regulate the opening or closing of the electromagnet.

[0013] Furthermore, it also includes an indicator light, which is electrically connected to the control unit and is used to display the working status of the mixing unit. When the indicator light is red, the mixing unit is in the working state, and when the indicator light is green, the mixing unit is in the stopped state.

[0014] The utility model has the advantages that: the utility model solves the problem of time-consuming and poor effect of manual mixing, and ensures the effect of the reagent without deviation due to inability to fully mix the magnetic beads.

[0015] The utility model is described in detail below with reference to the accompanying drawings and embodiments. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 It is a schematic diagram of the structure of the utility model.

[0017] Explanation of the accompanying drawings: 1. outer shell; 2. clamping unit; 3. magnetic unit; 4. mixing unit; 5. test tube. DETAILED DESCRIPTION

[0018] In order to further explain the technical means and effects adopted by the present invention to achieve the predetermined purpose, the specific implementation methods, structural features and effects of the present invention are described in detail below in conjunction with the accompanying drawings and embodiments.

[0019] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments of the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0020] In the description of the present invention, it should be understood that the terms "center", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "aligned", "overlap", "bottom", "inside", "outside", etc., indicating orientations or positional relationships, are based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation on the present invention.

[0021] The terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" and "second" may explicitly or implicitly include one or more of the features; in the description of the present utility model, unless otherwise specified, "plurality" means two or more.

[0022] Example 1

[0023] This embodiment provides Figure 1 A magnetic bead mixer shown includes an outer shell 1 and a mixing unit 4, wherein the mixing unit is a vortex oscillator. The upper surface of the mixing unit 4 is connected to the lower part of the outer shell 1. The outer shell 1 is provided with a limiting through hole running through the middle thereof, so that the test tube can be placed on the mixing unit 4 through the limiting through hole. A clamping unit 2 is provided on the top of the outer shell 1, and the clamping unit 2 is used to fix the test tube 5 so that the mixing unit drives the test tube 5 to vibrate.

[0024] Specifically, when the fully automatic chemiluminescence instrument reagent is not in use, all the magnetic beads sink to the bottom of the tube due to gravity. The test tube is placed in the magnetic bead mixer until the bottom of the test tube contacts the mixing unit 4; the control unit controls the clamping unit 2 to clamp the test tube; the magnetic unit 3 works to adsorb the magnetic beads deposited at the bottom of the test tube to the vicinity of the magnetic unit 3, that is, the middle of the test tube; then the magnetic unit 3 stops working, and the mixing unit 4 starts working to mix the magnetic beads in the reagent evenly.

[0025] Furthermore, the clamping unit 2 includes an elastic member, a soft pad, and two relatively arranged clamping members. The elastic member is used to adjust the tightness of the two relatively arranged clamping members so as to restrict the test tube 5 between the two clamping members; the soft pad is arranged on the inner side of the clamping member so as to clamp the soft pad on the outer periphery of the test tube 5.

[0026] Furthermore, the clamping unit 2 is fixedly arranged on the top of the outer shell 1, and the control unit controls the clamping and loosening of the clamping member of the clamping unit 2; the clamping member is a pair of opposite arc-shaped pressure plates, and the clamping member cushion is arranged on the clamping member to ensure that the clamping member can clamp the test tube while protecting the test tube.

[0027] Furthermore, when the mixing unit 4 is working, the elastic member connects the two oppositely arranged clamping members, and the elastic member is a spring to generate opposite pulling forces on the two clamping members, thereby ensuring that when the mixing unit 4 is working, pulling forces are generated between the two clamping members.

[0028] Furthermore, it also includes a control unit, which is arranged on the mixing unit 4 and is electrically connected to the mixing unit 4.

[0029] Furthermore, it also includes a power supply unit, which is arranged in the vortex oscillator, and the power supply unit is electrically connected to the control unit and the vortex oscillator to provide power support for the control unit; the power supply unit can be powered by an external power supply; preferably, the power supply unit is a battery inside the vortex oscillator.

[0030] Furthermore, the outer shell 1 is a double-layer structure, and a placement cavity is formed between the double-layer structure of the outer shell 1, and the magnetic unit 3 is arranged in the placement cavity.

[0031] Furthermore, the magnetic unit 3 is an electromagnet. When the control unit supplies power to the magnetic unit 3 , the magnetic unit 3 becomes magnetic. When the control unit supplies power to the magnetic unit 3 , the magnetic unit 3 becomes non-magnetic.

[0032] Furthermore, a plurality of magnetic units 3 may be disposed inside the outer shell 1 . The plurality of magnetic units 3 are arranged vertically and work independently, and the magnetism of a certain magnetic unit 3 is controlled by the control unit.

[0033] Furthermore, the vortex oscillator is connected to the bottom of the outer shell 1 by screws, so that the outer shell 1 plays a protective role.

[0034] Furthermore, the magnetic bead mixer also includes an indicator light, which is electrically connected to the control unit and is used to display the working status of the mixing unit. When the indicator light is red, the mixing unit is in a working state, and when the indicator light is green, the mixing unit is in a stopped state.

[0035] In a preferred embodiment provided by the present utility model, as Figure 1 As shown, the working process of the magnetic bead mixer is as follows:

[0036] Insert the test tube 5 containing the reagent and the magnetic beads into the limiting through hole in the middle of the outer shell 1, and place one end of the test tube 5 on the vortex oscillator. At this time, the magnetic beads are precipitated at the bottom of the test tube 5. The clamping unit 2 is adjusted to clamp one end of the test tube 5. When the bottom of the test tube 5 touches the vortex oscillator, the control unit starts to work; at this time, the indicator light keeps showing red.

[0037] Next, the control unit controls the electromagnet to be energized. The electromagnet is magnetic, and the magnetic beads deposited at the bottom of the test tube 5 are adsorbed near the electromagnet. After 3-5 seconds, the control unit cuts off the power to the electromagnet, and the vortex oscillator starts to work. The mixing unit 4 drives the test tube 5 to vibrate, making the mixing more uniform. At this time, the indicator light keeps showing yellow light.

[0038] Finally, after the vortex oscillator completes the mixing work, the control unit controls the vortex oscillator to stop working, and the indicator light shows green.

[0039] The utility model solves the problem of time-consuming and poor effect of manual mixing, and ensures the effect of the reagent without deviation due to inability to fully mix the magnetic beads.

[0040] The above contents are further detailed descriptions of the present invention in combination with specific preferred implementations, and the specific implementation of the present invention cannot be considered to be limited to these descriptions. For ordinary technicians in the technical field to which the present invention belongs, several simple deductions or substitutions can be made without departing from the concept of the present invention, which should be regarded as falling within the protection scope of the present invention.

Claims

1. A magnetic bead mixer, characterized in that: The invention comprises an outer shell (1) and a mixing unit (4), wherein the upper surface of the mixing unit (4) is connected to the bottom of the outer shell (1), a limiting through hole is vertically opened on the outer shell (1) and passes through the center of the circle, a test tube (5) is placed in the outer shell (1), a clamping unit (2) is arranged on the top of the outer shell (1), and the clamping unit (2) is used to fix the test tube (5), and also comprises a magnetic unit (3), and the magnetic unit (3) is arranged in the outer shell (1).

2. A magnetic bead mixer as claimed in claim 1, characterized in that: The clamping unit (2) comprises an elastic member, a soft pad, and two clamping members arranged opposite to each other. The elastic member is used to adjust the tightness of the two clamping members arranged opposite to each other so as to restrict the test tube (5) between the two clamping members. The soft pad is arranged on the inner side of the clamping member so as to clamp the soft pad on the outer periphery of the test tube (5).

3. A magnetic bead mixer as claimed in claim 2, characterized in that: The clamping piece is arc-shaped, and a circle is formed between the two clamping pieces.

4. A magnetic bead mixer as claimed in claim 2, characterized in that: The elastic member is a spring to generate opposite pulling forces on the two clamping members.

5. A magnetic bead mixer as claimed in claim 1, characterized in that: It also comprises a control unit, which is arranged on the mixing unit (4) and is electrically connected to the mixing unit (4).

6. A magnetic bead mixer as claimed in claim 5, characterized in that: It also comprises a power supply unit, which is arranged in the mixing unit (4) and is electrically connected to the mixing unit (4) and the control unit respectively.

7. A magnetic bead mixer as claimed in claim 1, characterized in that: The outer shell (1) is a double-layer structure, a placement cavity is formed between the double-layer structure of the outer shell (1), and the magnetic unit (3) is arranged in the placement cavity.

8. A magnetic bead mixer as claimed in claim 5, characterized in that: The magnetic unit (3) is an electromagnet, and the electromagnet is electrically connected to the control unit so that the control unit can regulate the opening or closing of the electromagnet.

9. A magnetic bead mixer as claimed in claim 8, characterized in that: It also comprises an indicator light, which is electrically connected to the control unit and is used to display the working state of the mixing unit (4); when the indicator light is red, the mixing unit (4) is in the working state; when the indicator light is green, the mixing unit (4) is in the stopped state.