Liquid chromatographic column with sieve plate easy to replace

Abstract

The utility model relates to the technical field of liquid chromatographic columns, and discloses a liquid chromatographic column with a sieve plate easy to replace, which comprises a pipe sleeve, a liquid chromatographic column convenient-to-replace mechanism is arranged in the pipe sleeve, and a liquid chromatographic column blocking mechanism is arranged at the top of the liquid chromatographic column convenient-to-replace mechanism. The convenient liquid chromatographic column replacement mechanism comprises a liquid chromatographic column assembly and a liquid chromatographic column replacement assembly, and the connecting pipe is arranged outside the liquid chromatographic column replacement assembly. According to the liquid chromatographic column with the sieve plate easy to replace, a rotating ring is fixed, so that the outer part of the rotating ring is taken out, and then an insertion plate outside a filter plate is inserted into a connecting pipe, so that the filter plate can be quickly replaced, and meanwhile, the filter plate can be quickly centralized and prevented from deviating; a liquid chromatographic column blocking mechanism is matched with a liquid chromatographic column, so that a replacement mechanism can be conveniently used, and a blocking column outside a disc is inserted into a blocking connecting pipe, so that the device can be conveniently blocked.

Description

Technical Field

[0001] The utility model relates to the technical field of liquid chromatography columns, in particular to a liquid chromatography column with an easily replaceable sieve plate. Background Art

[0002] The chromatographic column plays a role of separation in the liquid phase system and is one of the core components of the liquid chromatography system, and the sieve plate is a crucial component thereof. Therefore, a liquid chromatography column with an easily replaceable sieve plate is required.

[0003] According to a liquid chromatography column disclosed in the patent website (authorization announcement number: CN 215894510 U), "The utility model discloses a liquid chromatography column. Aiming at the problem that the chromatography column filler collapses and the chromatography column needs to be disassembled for maintenance, the following technical solutions are provided: a liquid chromatography column, comprising an outer shell with an internal thread, the two ends of the outer tube are threadedly connected to a moving tube with an external thread, a filling tube filled with fillers and fixedly connected to the outer shell is arranged inside the moving tube, a column head assembly is arranged at both ends of the moving tube, the column head assembly is pressed against the filter plate tightly attached to the filler and connected to the filling tube, a rotating ring with an internal thread is arranged at both ends of the outer shell, the rotating ring and the moving tube are threadedly connected, and the outer shell is provided with a locking assembly for locking the rotating ring. By rotating the rotating ring arranged on the outer shell, the moving tube rotates along the internal thread of the rotating ring due to the external thread, so that the column head assembly connected to the moving tube pushes the filter plate toward the filler, thereby reducing the dead volume and improving the column efficiency of the liquid chromatography column; the locking assembly is arranged on the outer shell, which can effectively prevent misoperation."

[0004] In view of the above description, the applicant believes that the following problems exist: when the device is in use, the fasteners are loosened to remove the locking assembly, and the rotating ring is rotated to move the moving tube toward the packing. When obvious resistance is felt, the rotation is stopped and the locking assembly is reinstalled. Then the liquid chromatography column can be reused. When the filter screen is installed on the chromatography column, it is necessary to straighten it and place the filter screen offset. Since the filter screen is small, the operation is more troublesome. Utility Model Content

[0005] The utility model aims to provide a liquid chromatography column with an easily replaceable sieve plate, so as to solve the problems raised in the above-mentioned background technology.

[0006] To achieve the above object, the utility model provides the following technical solution: a liquid chromatography column with an easily replaceable sieve plate, comprising a tube sleeve, a liquid chromatography column replacement mechanism is arranged inside the tube sleeve, and a liquid chromatography column blocking mechanism is arranged on the top of the liquid chromatography column replacement mechanism;

[0007] The liquid chromatography column replacement mechanism comprises a liquid chromatography column assembly and a liquid chromatography column replacement assembly, and a connecting pipe is arranged outside the liquid chromatography column replacement assembly.

[0008] Preferably, the liquid chromatography column assembly includes a column body, which is arranged inside a sleeve, a chromatography column filler is fixedly connected to the inside of the column body, and a connecting column is fixedly connected to the end of the column body. The provision of the sleeve is beneficial to protecting the device.

[0009] Preferably, the liquid chromatography column replacement assembly includes a connecting tube, which is arranged at the top of the connecting column, the outside of the connecting tube is movably connected with a rotating ring, a spring is arranged at a middle position between the inside of the rotating ring and the outside of the connecting tube, the inside of the connecting tube is movably connected with a sliding bead, the inside of the connecting tube is threadedly connected with a fixing ring at one end away from the sliding bead, the inside of the connecting tube is slidably connected with an insert plate, the top of the insert plate is fixedly connected with a filter plate, the inside of the fixing ring is slidably connected with a blade ring, the outside of the fixing ring is slidably connected with a sealing ring, and the outside of the fixing ring is threadedly connected with a fixed rotating ring. Since the column is provided, it is beneficial to provide a placement space for the chromatographic column filler.

[0010] Preferably, through holes are provided at corresponding positions of the fixing ring and the filter plate, and the filter plate is slidably connected to the inside of the fixing ring. The setting of the fixing ring facilitates connection with the fixed rotating ring.

[0011] Preferably, through holes are provided at corresponding positions of the connecting pipe and the connecting column, and the connecting pipe is movably connected to the outside of the connecting column. The provision of the connecting pipe is conducive to providing an installation foundation for other components.

[0012] Preferably, through holes are provided at corresponding positions of the rotating ring and the connecting column, and the rotating ring is threadedly connected to the outside of the connecting column. The provision of the rotating ring facilitates connection with the connecting column.

[0013] Preferably, the liquid chromatography column blocking mechanism includes a blocking connecting tube, which is fixedly connected to the outside of the fixed rotating ring, a blocking column is slidably connected to the inside of the blocking connecting tube, and a disc is fixedly connected to the outside of the blocking column. The provision of the blocking column is beneficial for blocking the blocking connecting tube.

[0014] Compared with the prior art, the utility model provides a liquid chromatography column with an easily replaceable sieve plate, which has the following beneficial effects:

[0015] 1. The sieve plate of the liquid chromatography column is easy to replace. Since a liquid chromatography column assembly and a liquid chromatography column replacement assembly are arranged in the liquid chromatography column replacement mechanism, the fixed rotating ring is taken out of the fixed ring, and then the insertion plate outside the filter plate is inserted into the inside of the connecting tube, which is conducive to quickly replacing the filter plate and quickly straightening the filter plate to prevent the filter plate from shifting.

[0016] 2. The sieve plate is easy to replace the liquid chromatography column, and the liquid chromatography column plugging mechanism is used in conjunction with the liquid chromatography column replacement mechanism. The plugging column outside the disc is inserted into the inside of the plugging connecting pipe, which is conducive to plugging the device. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the following briefly introduces the drawings required for use in the description of the embodiments. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative labor:

[0018] Figure 1 This is a schematic diagram of the appearance structure of the utility model;

[0019] Figure 2 This is a schematic diagram of the structure of the liquid chromatography column of the utility model that is easy to replace;

[0020] Figure 3 This is a schematic diagram of the structure of the liquid chromatography column assembly of the utility model, which is convenient for replacing the liquid chromatography column;

[0021] Figure 4 This is a schematic diagram of the structure of the liquid chromatography column replacement assembly of the utility model, which is convenient for replacing the liquid chromatography column;

[0022] Figure 5 It is a schematic diagram of the structure of the plugging mechanism of the liquid chromatography column of the utility model.

[0023] In the figure: 1. sleeve; 2. liquid chromatography column replacement mechanism; 21. liquid chromatography column assembly; 211. column body; 212. chromatography column filler; 213. connecting column; 22. liquid chromatography column replacement assembly; 221. connecting tube; 222. rotating ring; 223. spring; 224. sliding bead; 225. filter plate; 226. fixed ring; 227. sealing ring; 228. blade ring; 229. fixed rotating ring; 2210. insert plate; 3. liquid chromatography column blocking mechanism; 31. blocking connecting tube; 32. blocking column; 33. disc. DETAILED DESCRIPTION

[0024] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0025] In the present invention, unless otherwise clearly specified and limited, the terms "install", "connect", "connect", "fix" and the like should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0026] Embodiment 1:

[0027] See also Figure 1-5 The utility model provides a technical solution: a liquid chromatography column with an easily replaceable sieve plate, comprising a tube sleeve 1, a liquid chromatography column easy replacement mechanism 2 is arranged inside the tube sleeve 1, and a liquid chromatography column blocking mechanism 3 is arranged on the top of the liquid chromatography column easy replacement mechanism 2;

[0028] The liquid chromatography column replacement mechanism 2 comprises a liquid chromatography column assembly 21 and a liquid chromatography column replacement assembly 22 , and a connecting tube 221 is arranged outside the liquid chromatography column replacement assembly 22 .

[0029] Furthermore, the liquid chromatography column assembly 21 includes a column 211, which is arranged inside the sleeve 1. The interior of the column 211 is fixedly connected to a chromatography column filler 212, and the end of the column 211 is fixedly connected to a connecting column 213. Since the sleeve 1 is provided, it is beneficial to protect the device.

[0030] Furthermore, the liquid chromatography column replacement assembly 22 includes a connecting tube 221, which is arranged at the top of the connecting column 213, and the outside of the connecting tube 221 is movably connected with a rotating ring 222, and a spring 223 is arranged at a middle position between the inside of the rotating ring 222 and the outside of the connecting tube 221, and the inside of the connecting tube 221 is movably connected with a sliding bead 224, and the end of the inside of the connecting tube 221 away from the sliding bead 224 is threadedly connected with a fixing ring 226, the inside of the connecting tube 221 is slidably connected with an insert plate 2210, and the top of the insert plate 2210 is fixedly connected with a filter plate 225, the inside of the fixing ring 226 is slidably connected with a blade ring 228, the outside of the fixing ring 226 is slidably connected with a sealing ring 227, and the outside of the fixing ring 226 is threadedly connected with a fixed rotating ring 229. Since the column 211 is provided, it is beneficial to provide a placement space for the chromatographic column filler 212.

[0031] Furthermore, through holes are provided at corresponding positions of the fixing ring 226 and the filter plate 225 , and the filter plate 225 is slidably connected inside the fixing ring 226 . The fixing ring 226 is provided to facilitate connection with the fixed rotating ring 229 .

[0032] Furthermore, through holes are provided at corresponding positions of the connecting tube 221 and the connecting column 213, and the connecting tube 221 is movably connected to the outside of the connecting column 213. The provision of the connecting tube 221 is conducive to providing an installation foundation for other components.

[0033] Furthermore, through holes are provided at corresponding positions of the rotating ring 222 and the connecting column 213 , and the rotating ring 222 is threadedly connected to the outside of the connecting column 213 . The provision of the rotating ring 222 facilitates connection with the connecting column 213 .

[0034] Embodiment two:

[0035] See also Figure 5 In combination with Example 1, it is further obtained that the liquid chromatography column blocking mechanism 3 includes a blocking connecting tube 31, which is fixedly connected to the outside of the fixed rotating ring 229, and the inside of the blocking connecting tube 31 is slidably connected with a blocking column 32, and the outside of the blocking column 32 is fixedly connected with a disc 33. Since the blocking column 32 is provided, it is beneficial to block the blocking connecting tube 31.

[0036] In actual operation, when the device is used, first, the insert plate 2210 outside the filter plate 225 is placed inside the connecting tube 221, and then the fixing ring 226 is placed inside the connecting tube 221 and rotated to fix it. Then, the sealing ring 227 is placed outside the fixing ring 226, and then the sealing ring 227 is placed inside the fixing ring 226, and the fixing rotating ring 229 is rotated outside the fixing ring 226 to fix it. Then, the column 211 is placed inside the pipe sleeve 1, and then the connecting tube is connected. The rotating ring 222 on the outside of 221 is aligned with the connecting column 213 and inserted, the rotating ring 222 slides on the outside of the connecting tube 221, and the connecting column 213 pushes the sliding bead 224 to move inside the connecting tube 221, and then the spring 223 pushes the rotating ring 222 to slide on the outside of the connecting tube 221, so that the sliding bead 224 enters the inside of the connecting column 213 to restrict it, and then the rotating ring 222 is rotated to fix it to complete the installation, and then the blocking column 32 on the outside of the disc 33 is inserted into the inside of the blocking connecting tube 31.

[0037] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device. In the absence of further restrictions, the elements defined by the statement "comprise a ..." do not exclude the presence of other identical elements in the process, method, article or device including the elements.

Claims

1. A liquid chromatography column with an easily replaceable sieve plate, comprising a tube sleeve (1), characterized in that: A liquid chromatography column replacement mechanism (2) is arranged inside the tube sleeve (1), and a liquid chromatography column blocking mechanism (3) is arranged on the top of the liquid chromatography column replacement mechanism (2); The liquid chromatography column replacement mechanism (2) comprises a liquid chromatography column assembly (21) and a liquid chromatography column replacement assembly (22), and a connecting tube (221) is arranged outside the liquid chromatography column replacement assembly (22).

2. A liquid chromatography column with an easily replaceable sieve plate according to claim 1, characterized in that: The liquid chromatography column assembly (21) comprises a column body (211), wherein the column body (211) is arranged inside a pipe sleeve (1), a chromatography column filler (212) is fixedly connected inside the column body (211), and a connecting column (213) is fixedly connected to the end of the column body (211).

3. A liquid chromatography column with an easily replaceable sieve plate according to claim 2, characterized in that: The liquid chromatography column replacement component (22) comprises a connecting tube (221), wherein the connecting tube (221) is arranged at the top of the connecting column (213), the outside of the connecting tube (221) is movably connected to a rotating ring (222), a spring (223) is arranged at a middle position between the inside of the rotating ring (222) and the outside of the connecting tube (221), the inside of the connecting tube (221) is movably connected to a sliding bead (224), the inside of the connecting tube (221) is threadedly connected to a fixing ring (226) at one end away from the sliding bead (224), the inside of the connecting tube (221) is slidably connected to an insert plate (2210), the top of the insert plate (2210) is fixedly connected to a filter plate (225), the inside of the fixing ring (226) is slidably connected to a blade ring (228), the outside of the fixing ring (226) is slidably connected to a sealing ring (227), and the outside of the fixing ring (226) is threadedly connected to a fixed rotating ring (229).

4. A liquid chromatography column with an easily replaceable sieve plate according to claim 3, characterized in that: Through holes are provided at corresponding positions of the fixing ring (226) and the filter plate (225), and the filter plate (225) is slidably connected inside the fixing ring (226).

5. The liquid chromatography column with easily replaceable sieve plate according to claim 3, characterized in that: Through holes are provided at corresponding positions of the connecting tube (221) and the connecting column (213), and the connecting tube (221) is movably connected to the outside of the connecting column (213).

6. A liquid chromatography column with an easily replaceable sieve plate according to claim 3, characterized in that: Through holes are provided at corresponding positions of the rotating ring (222) and the connecting column (213), and the rotating ring (222) is threadedly connected to the outside of the connecting column (213).

7. A liquid chromatography column with an easily replaceable sieve plate according to claim 5, characterized in that: The liquid chromatography column blocking mechanism (3) comprises a blocking connecting tube (31), wherein the blocking connecting tube (31) is fixedly connected to the outside of a fixed rotating ring (229), a blocking column (32) is slidably connected to the inside of the blocking connecting tube (31), and a disc (33) is fixedly connected to the outside of the blocking column (32).

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