Magnetic frame

By designing a magnetic rack including bottom plate, side panel, orifice plate, lifting rack and magnetic column, the existing magnetic rack structure is solved and the problem of the complex structure and inability to meet the needs of multiple specifications is achieved, and the liquid phase separation of magnetic beads and experimental efficiency is improved.

CN222886733UActive Publication Date: 2025-05-20魏雷雷
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Patent Information

Application Number
CN202421667512.9
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-07-15
Publication Date
2025-05-20
Estimated Expiration
2034-07-15

AI Technical Summary

Technical Problem

The existing magnetic rack has a complex structure and high production cost. It cannot meet the needs of single tubes, eight-line tubes and 96-well plates, and it is impossible to separate the magnetic beads from the liquid phase.

Method used

A magnetic rack including a base plate, side panel, orifice plate, lifting rack and magnetic column is designed. The outer frame structure of the test tube rack can be used to place tubes of different specifications, and the separation of magnetic beads is achieved through the lifting and magnetic columns.

Benefits of technology

The function of separation of magnetic beads from the liquid phase is realized, which is convenient for operators to absorb the purified liquid, and the magnetic stand can be flexibly spliced ​​and used, suitable for the combination of standard single tubes, eight-tube tubes, 96-well plates and pipettes, improving experimental efficiency.

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Abstract

The utility model discloses a magnetic frame which comprises a bottom plate, side panels, a pore plate, a lifting frame and magnetic columns, the left side and the right side of the bottom plate are respectively provided with one side panel, the top of each side panel is provided with the pore plate, the lifting frame is arranged between the two side panels, and the lifting frame is provided with a plurality of columns of magnetic columns. And two adjacent rows of holes of the pore plate share one row of magnetic columns. According to the magnetic rack, an outer frame structure of a test tube rack is adopted, a single tube, an eight-row tube and a 96-hole plate can be placed, the lifting magnetic columns are adopted on the magnetic attraction device, and the lifting magnetic columns can move the attracted magnetic beads upwards so that the magnetic beads can be separated from a liquid phase.
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Description

Technical Field

[0001] The utility model belongs to the technical field of inspection and quarantine laboratory appliances, and particularly relates to a magnetic rack. Background Art

[0002] A magnetic rack is a device used to separate magnetic microspheres from a liquid. Usually, a magnet is provided on the magnetic rack, and the magnetic microspheres are made of iron or other similar magnetic metal materials. In nucleic acid separation, the biotin magnetic bead separation method is often used, that is, nucleic acid is adsorbed on biochemically modified magnetic beads, and then the magnetic rack is used to adsorb and precipitate the magnetic beads to achieve the separation of nucleic acid from other substances. Among the magnetic racks in the prior art, there are two types. One can only use single tubes or octuplet tubes, and the other is for 96-well plates. However, this kind of magnetic rack has a complex structure and a high manufacturing cost, is not suitable for large-scale promotion and use, and cannot separate magnetic beads from the liquid phase during the operation process. Therefore, it is necessary to design a magnetic rack with a simple structure that can meet the use of single tubes, octuplet tubes, and 96-well plates. Content of the Utility Model

[0003] The utility model aims at the above-mentioned deficiencies of the prior art and invents a magnetic rack.

[0004] In order to achieve the above purpose, the utility model adopts the following technical scheme:

[0005] A magnetic rack includes a bottom plate, side panels, a well plate, a lifting frame, and magnetic columns. One side panel is provided on each of the left and right sides of the bottom plate. A well plate is provided on the top of the side panels. A lifting frame is provided between the two side panels, and several columns of magnetic columns are provided on the lifting frame. One column of magnetic columns is shared by two adjacent columns of holes on the well plate.

[0006] The magnetic rack of the utility model adopts the outer frame structure of a test tube rack, can place single tubes, octuplet tubes, and 96-well plates. In the magnetic adsorption setting, lifting magnetic columns are adopted. The lifting magnetic columns can move the adsorbed magnetic beads upward to separate the magnetic beads from the liquid phase, which is convenient for the operator to aspirate the purified liquid.

[0007] Further, the lifting frame includes vertical rods and cross bars. Rectangular grooves for lifting the vertical rods are provided on the side panels. The magnetic columns are provided on the vertical rods, and the two ends of the vertical rods are connected into a whole through the cross bars.

[0008] Further, it also includes adsorption magnets and iron sheets. The adsorption magnets are arranged on both sides of the vertical rods and are located in the rectangular grooves; iron sheets are provided at the top of the rectangular grooves, and the lifting and positioning of the lifting frame can be controlled through the cooperation of the adsorption magnets and the iron sheets.

[0009] Further, the well plate is a 96-well plate, which is convenient for placing 96-well EP plates.

[0010] Further, it also includes an L-shaped connector and an L-shaped groove. One end of the bottom plate is rotatably provided with an L-shaped connector, and the other end of the bottom plate is provided with an L-shaped groove that cooperates with the L-shaped connector, which facilitates connecting two adjacent magnetic racks together for convenient experiment operation and avoids the magnetic repulsion between them.

[0011] The advantages of the present utility model are as follows: The magnetic rack provided by the present utility model can be flexibly spliced and used. The magnetic beads can be conveniently separated from the liquid phase through the lifting magnetic columns, and the user can easily aspirate the lower layer liquid in the EP tube; it can be used in cooperation with standard single tubes, octuplets, 96-well plates, and pipettes to improve the experiment efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0012] Figure 1 is a perspective view of a magnetic rack of the present utility model;

[0013] Figure 2 is a right view of a magnetic rack of the present utility model;

[0014] Figure 3 is a perspective view of the lifting rack in a magnetic rack of the present utility model;

[0015] Figure 4 is a perspective view of the bottom plate in a magnetic rack of the present utility model. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0016] The present utility model will be described in detail below with reference to the accompanying drawings:

[0017] In the description of the present utility model, it should be noted that the orientation or positional relationship indicated by "left", "right", "longitudinal", "transverse", etc. is based on the orientation or positional relationship shown in the drawings, or the orientation or positional relationship in which the product of the present utility model is usually placed during use. It is only for the convenience of describing the present utility model and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, as well as a specific orientation structure and operation. Therefore, it should not be construed as a limitation to the present utility model.

[0018] Such as Figures 1-4As shown in the figure, a magnetic rack includes a bottom plate 1, side panels 2, a perforated plate 3, a lifting rack 4, magnetic columns 5, adsorption magnets 6, iron sheets 7, L-shaped connectors 8 and L-shaped grooves 9. On the left and right sides of the bottom plate 1, there is a side panel 2 each. On the top of the side panel 2, there is a perforated plate 3. The side panel 2 supports the bottom plate 1 and the perforated plate 3 in parallel. The perforated plate 3 is a 96-well plate and can hold single tubes, eight-well strip tubes and 96-well plates. Between the two side panels 2, there is a lifting rack 4. On the lifting rack 4, there are 6 columns of magnetic columns 5 (in this embodiment, the longitudinal direction is the column and the horizontal direction is the row). The adjacent two columns of holes on the perforated plate 3 share one column of magnetic columns 5. The width of the magnetic column 5 is slightly smaller than the gap between the holes on the perforated plate 3. The lifting rack 4 includes a vertical rod 41 and a horizontal rod 42. On the side panel 2, there is a rectangular groove 21 for lifting the vertical rod 41. The magnetic column 5 is arranged on the vertical rod 41. The number of magnetic columns 5 on the vertical rod 41 is the same as the number of rows of holes on the perforated plate 3. The two ends of the vertical rod 41 are connected into a whole by the horizontal rod 42.

[0019] To determine the upper position of the lifting rack 4, the adsorption magnets 6 are arranged on both sides of the vertical rod 41 and located in the rectangular groove 21. An iron sheet 7 is arranged at the top of the rectangular groove 21. When the lifting rack 4 is lifted to the highest point, the adsorption magnet 6 and the iron sheet 7 adsorb each other to fix the lifting rack 4.

[0020] To enable the magnetic rack to be spliced during use or to prevent the mutual repulsion of the magnetic forces between the magnetic columns 5 of the magnetic racks, an L-shaped connector 8 is rotatably arranged at one end of the bottom plate 1. A groove for accommodating the L-shaped connector 8 is arranged on the bottom plate 1. An L-shaped groove 9 that cooperates with the L-shaped connector 8 is arranged at the other end of the bottom plate 1. When splicing is needed, turn out the L-shaped connector 8, and then align the bottom plate of another magnetic rack with the turned-out L-shaped connector 8 and snap it into the L-shaped groove 9.

[0021] Although the specific implementation of the present invention has been described and explained in detail above, it should be pointed out that we can make various changes and modifications to the above implementation, but these do not depart from the spirit of the present invention and the scope recorded in the appended claims.

Claims

1. A magnetic frame, characterized in that: The invention comprises a bottom plate (1), a side panel (2), a hole plate (3), a lifting frame (4) and a magnetic column (5), wherein a side panel (2) is arranged on each of the left and right sides of the bottom plate (1), a hole plate (3) is arranged on the top of the side panel (2), a lifting frame (4) is arranged between the two side panels (2), a plurality of rows of magnetic columns (5) are arranged on the lifting frame (4), and two adjacent rows of holes of the hole plate (3) share a row of magnetic columns (5).

2. A magnetic frame according to claim 1, characterized in that: The lifting frame (4) comprises a longitudinal rod (41) and a transverse rod (42); a rectangular groove (21) for lifting the longitudinal rod (41) is provided on the side panel (2); the magnetic column (5) is arranged on the longitudinal rod (41); and the two ends of the longitudinal rod (41) are connected into a whole through the transverse rod (42).

3. A magnetic frame according to claim 2, characterized in that: It also comprises an adsorption magnet (6) and an iron sheet (7), wherein the adsorption magnet (6) is arranged on both sides of the longitudinal rod (41) and is located in the rectangular groove (21); and the iron sheet (7) is arranged on the top of the rectangular groove (21).

4. A magnetic frame according to claim 3, characterized in that: The well plate (3) is a 96-well plate.

5. A magnetic frame according to claim 4, characterized in that: It also comprises an L-shaped connecting piece (8) and an L-shaped groove (9); one end of the bottom plate (1) is provided with the L-shaped connecting piece (8) in a flippable manner, and the other end of the bottom plate (1) is provided with the L-shaped groove (9) used in conjunction with the L-shaped connecting piece (8).