CART cell preservation device capable of preventing direct light

Abstract

The utility model discloses a CART cell preservation device capable of preventing direct light, and relates to the technical field of CART cell preservation, the CART cell preservation device comprises a preservation box group and a preservation rotating stand, the inner bottom side of the preservation box group is horizontally provided with an expansion type damping track, and the preservation rotating stand is connected to the surface of a guide rod. According to the CART cell preservation device capable of preventing direct light, the outer surface of the visible box door is coated with an intelligent light adjusting film, so that on one hand, constant-temperature test tubes in the whole preservation box group can be observed through adjustment and use of the intelligent light adjusting film so as to confirm the current preservation state of CART cells, and on the other hand, the current preservation state of the CART cells can be confirmed through adjustment and use of the intelligent light adjusting film; according to the constant-temperature test tube storage device, light transmission of different degrees is achieved, CART cells stored inside are prevented from being directly irradiated by external light, adverse influences on the cells are reduced, the storage rotating stand and the protection cover can provide further structural protection for placement of constant-temperature test tubes, and damage caused by external acting force is avoided.

Description

Technical Field

[0001] The utility model relates to the technical field of CART cell preservation, and in particular to a CART cell preservation device capable of preventing direct light. Background Art

[0002] T cells, also called T lymphocytes, are a type of human white blood cells. They originate from hematopoietic stem cells in the bone marrow, mature in the thymus, and then migrate to the human blood, lymph, and surrounding tissues and organs to exert immune functions. They function as "soldiers" in the human body, able to resist and eliminate "enemies" such as infections, tumors, foreign bodies, etc.

[0003] In the laboratory, technicians use genetic engineering technology to activate T cells and install a positioning and navigation device CAR, or tumor chimeric antigen receptor, to transform ordinary "soldiers" such as T cells into "super soldiers", namely CAR-T cells. They use their "positioning and navigation device" CAR to specifically identify tumor cells in the body and release a large number of multiple effector factors through immune action. They can effectively kill tumor cells, thereby achieving the purpose of treating malignant tumors. Therefore, in order to ensure the activity of CART cytokines, a preservation device is needed to preserve them.

[0004] Conventional CART cell storage devices use a relatively closed and opaque structure to protect cells from direct exposure to external light. However, the use of this structure also makes it impossible for operators to observe and confirm the specific status inside the device, and they need to open and close the device repeatedly, making its convenience relatively limited when used.

[0005] Therefore, in view of this, the existing structure and defects are studied and improved, and a CART cell preservation device that prevents direct light is proposed. Utility Model Content

[0006] The purpose of the utility model is to provide a CART cell storage device that prevents direct light, so as to solve the problems raised in the above-mentioned background technology.

[0007] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a CART cell preservation device for preventing direct light, comprising a preservation box group and a preservation turntable, wherein an expandable damping track is horizontally installed on the inner bottom side of the preservation box group, and a guide rod is arranged on the top surface of the expandable damping track, the preservation turntable is connected to the surface of the guide rod, and a protective cover is inserted around the preservation turntable, and a constant temperature test tube is inserted in a circular array in the middle of the preservation turntable, the preservation box group comprises an anti-slip platform, an electronic constant temperature box, a visual box door, an electronic self-locking hinge and an intelligent dimming film, an electronic constant temperature box is installed on the top of the anti-slip platform, and a visual box door is arranged at the opening of the electronic constant temperature box, and an electronic self-locking hinge is connected to one side between the visual box door and the electronic constant temperature box, and the outer surface of the visual box door is covered with an intelligent dimming film.

[0008] Furthermore, the anti-slip platform and the electronic thermostatic box are in a fixed connection structure, and the electronic self-locking hinges are symmetrically arranged at the upper and lower ends of one side of the electronic thermostatic box.

[0009] Furthermore, the front and side facades of the visual door are made of transparent material, and the intelligent dimming film completely covers the outer surfaces of the front and side facades of the visual door.

[0010] Furthermore, the expansion damping track is installed on the bottom side of the inner side of the electronic thermostat using an embedded structure, and the guide rod is maintained parallel to the expansion damping track and is erected on the top surface of the expansion damping track.

[0011] Furthermore, the storage rotating rack includes a rotating table, a slot, a stabilizing pile and a main column. The edge surface of the rotating table is provided with a slot, and the top surface of the rotating table has a circular array of stabilizing piles, and a main column is vertically installed in the center of the rotating table.

[0012] Furthermore, the storage rotating rack also includes a fixed insert, a placement hole and a damping slider. The upper and lower ends of the main column are both equipped with a fixed insert, and a circular array of placement holes is opened on the surface of the fixed insert. The bottom of the rotating table is symmetrically installed with a damping slider.

[0013] Furthermore, the surface of the protective cover is sprayed with a transparent anti-ultraviolet paint, and the internal structure of the slot matches the bottom surface structure of the protective cover.

[0014] Furthermore, the damping slider is slidably connected to the guide rod, the inner diameter of the placement hole matches the outer diameter of the constant temperature test tube, and a hole matching the bottom surface structure of the constant temperature test tube is provided inside the fixed insert.

[0015] The utility model provides a CART cell storage device that prevents direct light exposure and has the following beneficial effects:

[0016] 1. The utility model uses a preservation box group, in which the front and side facades of the visual box door are made of transparent materials. Therefore, even when the visual box door and the electronic constant temperature box structure are closed, the operator can observe the interior of the entire preservation box group at any time to confirm the storage status of the constant temperature test tube. However, considering the preservation of CART cells inside the constant temperature test tube, it is necessary to avoid the influence of external light to the greatest extent. Therefore, the outer surface of the visual box door is covered with an intelligent dimming film, which can adjust the light transmittance when powered on, so that the operator can adjust the current light transmittance of the intelligent dimming film to flexibly observe the interior of the preservation box group at any time. The use of the above-mentioned mechanism can effectively avoid repeated opening and closing of the visual box door, thereby affecting the preservation stability of cells in the constant temperature test tube, but at the same time it is convenient for the user to make appropriate adjustments according to needs at any time, thereby ensuring the flexibility of the use of the device.

[0017] 2. The utility model uses a rotating rack and a protective cover, wherein fixed insert plates are symmetrically arranged at the upper and lower ends of the main column, and placement holes are opened in a circular array on the surface of the fixed insert plates, so that the constant temperature test tube can be directly inserted therein in the vertical direction. At the same time, a number of stabilizing piles are installed in a circular array on the surface of the rotating table. Therefore, when placing the constant temperature test tube, it is only necessary to vertically insert it into the placement hole on the surface of the fixed insert plate, and then insert the bottom end of the constant temperature test tube into the interior of the stabilizing pile. The use of the above structure can provide effective structural support and structural protection for the constant temperature test tube to the greatest extent, avoiding structural damage to the constant temperature test tube caused by external forces, and at the same time provide structural stability for the placement of the constant temperature test tube, avoiding the problem of leakage caused by tilting.

[0018] 3. The utility model adopts a protective cover with a transparent anti-ultraviolet coating on the surface. Since the protective cover is also made of transparent material, it will not cause structural interference to the observation of the operator. At the same time, the anti-ultraviolet coating on the surface of the protective cover can avoid direct exposure to external light when the smart dimming film is adjusting the transmittance, which may cause adverse effects on the cells inside the constant temperature test tube. At the same time, through the slots opened on the edge of the rotating table surface, the protective cover can be directly and vertically inserted therein, thereby forming a ring-shaped protective structure around the entire storage rotating rack, so as to further provide an effective external protective structure for the constant temperature test tube, so that even if the entire storage box group is directly subjected to external forces, it can provide buffer protection for the constant temperature test tube to a certain extent. In addition, by using the expansion damping track and the guide rod, the entire storage rotating rack can be horizontally moved in the electronic constant temperature box in the horizontal direction using the damping slider, so that the operator can take or place the constant temperature test tube. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 This is a schematic diagram of the three-dimensional structure of the main body of a CART cell preservation device that prevents direct light exposure in the utility model;

[0020] Figure 2 This is a schematic diagram of the three-dimensional structure of a storage box group of a CART cell storage device for preventing direct light exposure according to the utility model;

[0021] Figure 3 This is a schematic diagram of the three-dimensional structure of a storage rotating rack of a CART cell storage device that prevents direct light from being exposed to the present invention when viewed from above;

[0022] Figure 4 This is a top view of the three-dimensional structure of a storage rotating rack of a CART cell storage device that prevents direct light exposure according to the utility model.

[0023] In the figure: 1. Storage box set; 101. Anti-slip platform; 102. Electronic constant temperature box; 103. Visible box door; 104. Electronic self-locking hinge; 105. Intelligent dimming film; 2. Expansion damping track; 3. Guide rod; 4. Storage turntable; 401. Turntable; 402. Slot; 403. Stable pile; 404. Main column; 405. Fixed insert; 406. Placement hole; 407. Damping slider; 5. Protective cover; 6. Constant temperature test tube. DETAILED DESCRIPTION

[0024] The following is a further detailed description of the implementation of the present invention in conjunction with the accompanying drawings and examples. The following examples are used to illustrate the present invention, but cannot be used to limit the scope of the present invention.

[0025] like Figures 1 to 4As shown, a CART cell preservation device for preventing direct light includes a preservation box group 1 and a preservation rotating rack 4, an expandable damping track 2 is horizontally installed on the inner bottom side of the preservation box group 1, and a guide rod 3 is arranged on the top surface of the expandable damping track 2, the preservation rotating rack 4 is connected to the surface of the guide rod 3, and a protective cover 5 is inserted around the preservation rotating rack 4, and a constant temperature test tube 6 is inserted in a circular array in the middle of the preservation rotating rack 4, the preservation box group 1 includes an anti-slip platform 101, an electronic constant temperature box 102, a visual box door 103, an electronic self-locking hinge 104 and an intelligent dimming film 105, an electronic constant temperature box 102 is installed on the top of the anti-slip platform 101, and a visual box door 103 is arranged at the opening of the electronic constant temperature box 102, and an electronic self-locking hinge 104 is connected to one side between the visual box door 103 and the electronic constant temperature box 102, and the outer surface of the visual box door 103 The surface is covered with an intelligent dimming film 105, the anti-slip platform 101 and the electronic thermostat 102 are fixedly connected, and the electronic self-locking hinges 104 are symmetrically arranged at the upper and lower ends of one side of the electronic thermostat 102. The front and side facades of the visible door 103 are made of transparent material, and the intelligent dimming film 105 completely covers the outer surface of the front and side facades of the visible door 103. Since the front and side facades of the visible door 103 are made of transparent material, even when the visible door 103 and the electronic thermostat 102 structure are closed, the operator can observe the interior of the entire preservation box group 1 at any time. The intelligent dimming film 105 covering the outer surface of the visible door 103 can adjust its light transmittance function when it is powered on, so that the operator can adjust the current light transmittance of the intelligent dimming film 105 to flexibly observe the interior of the preservation box group 1 at any time.

[0026] like Figures 1 to 4 As shown, the storage rotating frame 4 includes a rotating table 401, a slot 402, a stabilizing pile 403 and a main column 404. The edge surface of the rotating table 401 is provided with a slot 402, and the top surface of the rotating table 401 is provided with a circular array of stabilizing piles 403, and the center of the rotating table 401 is vertically installed with a main column 404. The storage rotating frame 4 also includes a fixed insert plate 405, a placement hole 406 and a damping slider 407. The upper and lower ends of the main column 404 are both provided with fixed insert plates 405, and the surface of the fixed insert plate 405 is provided with a circular array of placement holes 406. The rotating table 401 The damping sliders 407 are symmetrically installed at the bottom, and fixed disks 405 are symmetrically inserted at the upper and lower ends of the main column 404, and placement holes 406 are opened in a circular array on the surface of the fixed disk 405, so that the constant temperature test tube 6 can be directly inserted therein in the vertical direction. At the same time, a number of stabilizing piles 403 are installed in a circular array on the surface of the rotating table 401. Therefore, when placing the constant temperature test tube 6, it only needs to be vertically inserted into the placement hole 406 on the surface of the fixed disk 405, and the bottom end of the constant temperature test tube 6 is inserted into the interior of the stabilizing pile 403.

[0027] like Figures 1 to 4 As shown, the expansion damping track 2 is installed on the bottom side of the inner side of the electronic thermostat 102 using an embedded structure, and the guide rod 3 is maintained parallel to the expansion damping track 2 and is mounted on the top surface of the expansion damping track 2. The surface of the protective cover 5 is sprayed with a transparent anti-ultraviolet paint, and the internal structure of the slot 402 matches the bottom surface structure of the protective cover 5. The damping slider 407 is slidably connected to the guide rod 3, the inner diameter of the placement hole 406 matches the outer diameter of the thermostat test tube 6, and the interior of the fixed plug-in plate 405 is provided with a hole that matches the outer diameter of the thermostat test tube 6. The bottom surface structure of the tube 6 has holes that match the structure. Since the protective cover 5 is also made of transparent material, it will not cause structural interference to the observation of the operator. At the same time, the anti-ultraviolet paint on the surface of the protective cover 5 can avoid direct exposure to external light when the smart dimming film 105 is adjusting the transmittance, which may cause adverse effects on the cells inside the constant temperature test tube 6. At the same time, through the slot 402 opened on the edge of the surface of the rotating table 401, the protective cover 5 can be directly inserted vertically therein, thereby forming a ring-shaped protective structure around the entire storage rotating rack 4.

[0028] In summary, if Figures 1 to 4 As shown, when the CART cell preservation device that prevents direct light is used, the visible box door 103 is first opened by the electronic self-locking hinge 104, and then the structural elasticity of the expansion damping track 2 can be used to horizontally pull out the preservation rotating rack 4 connected to the structure through the guide rod 3 from the inside of the electronic constant temperature box 102, and at the same time, the preservation rotating rack 4 with the protective cover 5 is inserted into the slot 402, and the damping slider 407 at the bottom of the rotating table 401 can be further used to horizontally move along the surface of the guide rod 3, thereby forming a two-stage pulling structure to ensure that the entire preservation rotating rack 4 is completely pulled out of the inside of the electronic constant temperature box 102;

[0029] After that, the thermostatic test tube 6 containing the CART cells can be inserted vertically into the fixed insert plate 405 with a placement hole 406 on the surface as needed, until the bottom end of the thermostatic test tube 6 is completely inserted into the stabilizing pile 403 provided on the surface of the rotating table 401;

[0030] Afterwards, the storage rotating rack 4 with the constant temperature test tube 6 can be pushed back into the electronic constant temperature box 102 by using the expansion damping track 2, the guide rod 3 and other structures, and then the visual box door 103 and the electronic constant temperature box 102 are structurally closed and locked by the electronic self-locking hinge 104. The user can adjust the light transmittance of the intelligent dimming film 105 coated on the outer surface of the visual box door 103 as needed, so as to observe the interior of the storage box group 1 at any time and avoid direct light exposure to the interior of the storage box group 1.

[0031] The embodiments of the present invention are provided for the purpose of illustration and description, and are not intended to be exhaustive or to limit the present invention to the disclosed forms. Many modifications and variations will be apparent to those of ordinary skill in the art. The embodiments are selected and described to better illustrate the principles and practical applications of the present invention, and to enable those of ordinary skill in the art to understand the present invention and thereby design various embodiments with various modifications suitable for specific uses.

Claims

1. A CART cell storage device for preventing direct light, comprising a storage box set (1) and a storage rotating rack (4), characterized in that: An expansion damping track (2) is horizontally installed on the inner bottom side of the storage box group (1), and a guide rod (3) is arranged on the top surface of the expansion damping track (2). The storage rotating frame (4) is connected to the surface of the guide rod (3), and a protective cover (5) is inserted around the storage rotating frame (4). A constant temperature test tube (6) is inserted in a circular array in the middle of the storage rotating frame (4). The storage box group (1) includes a non-slip platform (101), an electronic constant temperature box (102), and a A visual box door (103), an electronic self-locking hinge (104) and an intelligent dimming film (105); an electronic thermostatic box (102) is installed on the top of the anti-slip platform (101); a visual box door (103) is arranged at the opening of the electronic thermostatic box (102); an electronic self-locking hinge (104) is connected to one side of the visual box door (103) and the electronic thermostatic box (102); and an intelligent dimming film (105) is pasted on the outer surface of the visual box door (103).

2. A CART cell storage device for preventing direct light according to claim 1, characterized in that: The anti-slip floor (101) and the electronic thermostatic box (102) are in a fixed connection structure, and the electronic self-locking hinge (104) is symmetrically arranged at the upper and lower ends of one side of the electronic thermostatic box (102).

3. A CART cell storage device for preventing direct light according to claim 1, characterized in that: The front and side elevations of the visual door (103) are made of transparent material, and the smart dimming film (105) completely covers the outer surfaces of the front and side elevations of the visual door (103).

4. A CART cell storage device for preventing direct light according to claim 1, characterized in that: The expansion damping track (2) is installed on the bottom side of the inner side of the electronic thermostatic box (102) using an embedded structure, and the guide rod (3) is mounted on the top surface of the expansion damping track (2) in a structure that maintains a parallel relationship with the expansion damping track (2).

5. A CART cell storage device for preventing direct light according to claim 1, characterized in that: The storage rotating rack (4) comprises a rotating platform (401), a slot (402), a stabilizing pile (403) and a main column (404); the slot (402) is provided on the edge surface of the rotating platform (401), the stabilizing pile (403) is arranged in a circular array on the top surface of the rotating platform (401), and the main column (404) is vertically installed in the center of the rotating platform (401).

6. A CART cell storage device for preventing direct light according to claim 5, characterized in that: The storage rotating rack (4) further comprises a fixed insert plate (405), a placement hole (406) and a damping slider (407); the fixed insert plates (405) are inserted at both upper and lower ends of the main column (404); and the placement holes (406) are provided in an annular array on the surface of the fixed insert plate (405); and the damping slider (407) is symmetrically installed at the bottom of the rotating platform (401).

7. A CART cell storage device for preventing direct light according to claim 5, characterized in that: The surface of the protective cover (5) is sprayed with a transparent anti-ultraviolet paint, and the internal structure of the slot (402) matches the bottom surface structure of the protective cover (5).

8. A CART cell storage device for preventing direct light according to claim 6, characterized in that: The damping slider (407) is slidably connected to the guide rod (3), the inner diameter of the placement hole (406) matches the outer diameter of the constant temperature test tube (6), and a hole matching the bottom surface structure of the constant temperature test tube (6) is provided inside the fixed insert plate (405).

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