Magnetic resonance coil device for mouse experiment

Abstract

The utility model relates to a magnetic resonance coil device for a mouse experiment, and the device comprises a base which is provided with a first recess with an upward opening, and the first recess is used for a mouse to be put in from the opening; the cover can be used for covering at least one part of the first recess from the upper side in a releasable manner and is provided with a second recess with a downward opening, and when the cover covers the first recess, the first recess and the second recess jointly define an accommodating space for accommodating the mouse; the first coil is arranged in the base and is configured at the first concave part; and a second coil, which is installed in the cover, and is configured at the second recess.

Description

Technical Field

[0001] This application relates to the field of magnetic resonance technology, and particularly to a magnetic resonance coil device for mouse experiments. Background Art

[0002] Currently, there are few magnetic resonance coil devices for mouse experiments. There is no targeted professional design based on the particularity of mice, and there are generally defects such as poor operability and inconvenient use. Summary of the Invention

[0003] In view of this, this application provides a magnetic resonance coil device for mouse experiments.

[0004] In a first aspect, there is provided a magnetic resonance coil device for mouse experiments, including:

[0005] A base having a first recess with an upward opening for the mouse to be placed into the opening;

[0006] A cover that releasably covers at least a part of the first recess from above and has a second recess with a downward opening. When the cover covers the first recess, the first recess and the second recess together define a receiving space for the mouse;

[0007] A first coil installed in the base and disposed at the first recess;

[0008] A second coil installed in the cover and disposed at the second recess.

[0009] In some possible embodiments, both the first recess and the second recess are formed as arc-shaped recesses.

[0010] In some possible embodiments, the base has:

[0011] A plurality of pins protruding upward from the base outside the first recess;

[0012] The cover has:

[0013] A plurality of jacks extending upward outside the second recess;

[0014] Wherein, the cover is releasably installed on the base from above through the plug-in fit of the plurality of pins and the plurality of jacks.

[0015] In some possible embodiments, by means of the friction force between the plurality of pins and the plurality of jacks, the cover can be positioned at a plurality of height positions relative to the base.

[0016] In some possible embodiments, it further includes:

[0017] An ear rod, which is adjustably mounted to the base and has a rod head located in the accommodation space, and the rod head is used to abut against the ear of the mouse.

[0018] In some possible embodiments, the cover has a notch extending from the edge of the second recess, and the ear rod extends into the accommodation space through the notch.

[0019] In some possible embodiments, the base has:

[0020] An ear rod mounting hole, which extends in the first horizontal direction;

[0021] A first set screw, which is configured to enter and exit the ear rod mounting hole in a direction intersecting with the first horizontal direction by rotation;

[0022] The ear rod has:

[0023] A straight segment, which extends along the first horizontal direction and is inserted into the ear rod mounting hole; wherein, when the first set screw exits the ear rod mounting hole, the straight segment is allowed to move along the first horizontal direction and rotate around the first horizontal direction, and when the first set screw enters the ear rod mounting hole and abuts against the straight segment, the position of the straight segment in the first horizontal direction and around the first horizontal direction is positioned;

[0024] A non-straight segment, which extends from the front end of the straight segment to the front end side, and the front end of the non-straight segment forms the rod head, and when viewed along the first horizontal direction, the rod head and the straight segment are separated from each other.

[0025] In some possible embodiments, it further includes:

[0026] A tooth rod mounting hole, which extends in a second horizontal direction perpendicular to the first horizontal direction;

[0027] A second set screw, which is configured to enter and exit the tooth rod mounting hole in a direction intersecting with the second horizontal direction by rotation;

[0028] A tooth rod, which is inserted into the tooth rod mounting hole for the mouse to bite; when the first set screw exits the tooth rod mounting hole, the tooth rod is allowed to move along the second horizontal direction, and when the first set screw enters the tooth rod mounting hole and abuts against the tooth rod, the position of the tooth rod in the second horizontal direction is positioned;

[0029] A face mask, which is mounted on the front end of the dental rod and is used to cover the face of the mouse in a butting manner.

[0030] In some possible embodiments, it further includes:

[0031] A rope tying perforation, which is provided on the base and is located outside the first recess;

[0032] A tying rope, a part of which is used to tie the limbs of the mouse, and the other part passes through the rope tying perforation;

[0033] A third set screw, which is configured to be locked into the rope tying perforation by rotation, and thereby releasably engage the other part of the tying rope to the rope tying perforation.

[0034] In some possible embodiments, the first coil has a shape corresponding to the inner wall surface of the first recess and covers the back side of the inner wall surface of the first recess;

[0035] The second coil has a shape corresponding to the inner wall surface of the second recess and covers the back side of the inner wall surface of the second recess.

[0036] According to the magnetic resonance coil device provided by the present application, by releasing and installing the cover with the recess and the coil, variously sized mice as the objects to be studied can be easily applied to the device, and the cover can be used to protect and position the body of the mouse, improving the convenience of use of the mouse coil. Description of the Drawings

[0037] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings of the embodiments will be briefly introduced below. Obviously, the drawings in the following description only relate to some embodiments of the present application and do not limit the present application.

[0038] Figure 1 It is a schematic diagram of the magnetic resonance coil device provided by an embodiment of the present application in the usage state.

[0039] Figure 2 It is observed from another perspective Figure 1 The schematic diagram of the shown structure.

[0040] Figure 3 It is Figure 1 The schematic diagram of the magnetic resonance coil device in the present application when the cover is released.

[0041] Figure 4 It is observed from another perspective Figure 4 The schematic diagram of the shown structure.

[0042] Figure 5 It isFigure 1 Schematic diagram of the base part of the middle magnetic resonance coil device.

[0043] Figure 6 It is a schematic diagram of observing Figure 5 the shown structure from another perspective.

[0044] Figure 7 It is Figure 1 a schematic diagram of the first coil and the second coil of the middle magnetic resonance coil device.

[0045] Explanation of reference numerals:

[0046] DR1 - First direction, DR2 - Second direction, DR3 - Third direction;

[0047] 1 - Base, 1a - First recess, 1b - Ear rod mounting hole, 1c - Tooth rod mounting hole, 1d - Binding rope perforation;

[0048] 2 - Cover, 2a - Second recess, 2b - Jack, 2c - Notch;

[0049] 3 - First coil;

[0050] 4 - Second coil;

[0051] 5 - Plug;

[0052] 6 - Ear rod, 6a - Straight segment, 6b - Non - straight segment, 6b1 - Rod head;

[0053] 7 - Tooth rod;

[0054] 8 - Face mask;

[0055] 9 - First set screw;

[0056] 10 - Second set screw;

[0057] 11 - Third set screw;

[0058] 12 - Fourth set screw;

[0059] 13 - Cable;

[0060] 14 - Accommodating space. Detailed implementation manners

[0061] To make the objectives, technical solutions, and advantages of this application clearer, the following will clearly and completely describe the technical solutions of the embodiments of this application with reference to the accompanying drawings of the embodiments of this application. Obviously, the described embodiments are some but not all of the embodiments of this application. All other embodiments obtained by those of ordinary skill in the art based on the described embodiments of this application without creative efforts fall within the scope of protection of this application. It can be understood that, without conflict, some technical means described in the various embodiments herein can be replaced or combined with each other.

[0062] In the description of the specification and claims of this application, if there are terms such as "first", "second", etc., they are only used to distinguish the described objects and do not have any sequential or technical meanings. Thus, the objects defined with "first", "second", etc. can explicitly or implicitly include one or more of such objects. Also, words such as "one" or "a" do not indicate a quantity limitation but rather indicate the existence of at least one, and "multiple" means not less than two.

[0063] Figures 1 to 7 There is shown a magnetic resonance coil device for mouse experiments according to an embodiment of this application. The device mainly includes a base 1, a cover 2, a first coil 3, and a second coil 4. And, for the convenience of explaining this technology, a first direction DR1, a second direction DR2, and a third direction DR3 that are perpendicular to each other are introduced. Among them, the first direction DR1 and the second direction DR2 are horizontal directions, while the third direction DR3 is a vertical direction.

[0064] The base 1 has a first recess 1a with an upward opening, and the mouse can be placed into the first recess 1a from its upward opening. Specifically, the first recess 1a is formed as a downward arc-shaped recess and extends as a long straight groove in the second direction DR2. One end of the long straight groove penetrates the base 1, and the other end is blocked by a seat plate for installing a tooth bar 7 described later.

[0065] The cover 2 releasably covers at least a part of the first recess 1a from the upper side and has a second recess 2a with a downward opening. Specifically, the second recess 2a is formed as an arc-shaped recess recessed from its lower surface and extends and penetrates both ends of the cover 2 in the second direction DR2. And when the cover 2 covers the first recess 1a, the first recess 1a and the second recess 2a jointly define a receiving space 14 for receiving the mouse.

[0066] The first coil 3 is installed in the base 1 and is disposed at the first recess 1a. As Figure 7 shown, the first coil 3 has a shape (arc-shaped) corresponding to the inner wall surface of the first recess 1a and covers the back side (lower side) of the inner wall surface of the first recess 1a.

[0067] The second coil 4 is installed in the lid 2 and is disposed at the second recess 2a. As Figure 7 shown, the second coil 4 has a shape (arc shape) corresponding to the inner wall surface of the second recess 2a, and the lid 2 is on the back side (upper side) of the inner wall surface of the second recess 2a.

[0068] In this embodiment, the first coil 3 has a total of 8 first coil units arranged in an arc shape, the second coil 4 has a total of 8 second coil units arranged in an arc shape, and in the use state, the 8 first coil units and the 8 second coil units are symmetric in the third direction DR3.

[0069] In this embodiment, the lid 2 and the base 1 are specifically installed with each other by means of a plug-in structure, so as to realize the covering of the first recess 1a by the lid 2 and the formation of the accommodation space 14. Specifically, the base 1 has a plurality of pins 5, and the plurality of pins 5 project upward from the base 1 outside the first recess 1a. The lid 2 has a plurality of jacks 2b, and the plurality of jacks 2b extend upward from the lower surface of the lid 2 outside the second recess 2a, wherein the plurality of pins 5 are respectively inserted into the plurality of jacks 2b. In this way, through the plug-in cooperation of the pins 5 and the jacks 2b, the lid 2 can be releasably installed on the base 1 from the upper side, and the movement of the lid 2 relative to the base 1 in the horizontal direction can be restricted, thereby helping to maintain the accommodation space 14 and thus ensuring the stability of the experimental environment.

[0070] In some embodiments, the diameter of the pin 5 is substantially the same as the diameter of the jack 2b, so that when the two are plugged into each other, a frictional force greater than the gravity of the lid 2 is generated between the outer surface of the pin 5 and the inner surface of the jack 2b. In this way, by means of this frictional force, the lid 2 can be positioned at a plurality of height positions relative to the base 1 as needed, thereby appropriately adjusting the size of the accommodation space 14 to adapt to rats of corresponding body types.

[0071] The device further includes two ear rods 6, and the two ear rods 6 are adjustably installed on the base 1 and respectively have rod heads 6b1 located in the accommodation space 14. The two rod heads 6b1 are used to respectively abut against the two ears of the rat, so as to help position the body of the rat. And the lid 2 has a notch 2c extending from the edge of the second recess 2a, and the aforementioned ear rods 6 extend into the accommodation space 14 through the notch 2c. In the use state, the notch 2c can prevent the ear rods 6 from interfering with the lid 2.

[0072] The adjustment of the installation position of the ear rod 6 on the base 1 is achieved through the ear rod mounting hole 1b provided on the base 1 and the first set screw 9. The ear rod mounting hole 1b is a through hole extending in the first direction DR1, and the first set screw 9 is configured to enter and exit the ear rod mounting hole 1b along the third direction DR3 by its own rotation. The ear rod 6 has a straight segment 6a and a non-straight segment 6b, wherein the straight segment 6a extends along the first direction DR1 and is inserted into the ear rod mounting hole 1b, and the non-straight segment 6b extends from the front end of the straight segment 6a toward the front end side, and the front end of the non-straight segment 6b constitutes the aforementioned rod head 6b1. When viewed in the first horizontal direction, the rod head 6b1 and the straight segment 6a are spaced apart from each other. When the first set screw 9 exits the ear rod mounting hole 1b, the straight segment 6a is allowed to move along the first direction DR1 and rotate around the first direction DR1. When the first set screw 9 enters the ear rod mounting hole 1b and abuts against the straight segment 6a along the third direction DR3, the position of the straight segment 6a in the first direction DR1 and around the first direction DR1 is positioned. Based on such a design, in actual application, the height of the rod head 6b1 can be adjusted by rotating the ear rod 6 around the first direction DR1 (the rod head 6b1 moves on a circular path around the horizontal axis defined by the straight segment 6a), and the insertion depth of the rod head 6b1 can be adjusted by moving the ear rod 6 along the first direction DR1, thereby adapting to mice of various body types as the research objects.

[0073] In addition, the device further includes a tooth rod mounting hole 1c, a second set screw 10, a tooth rod 7, and a face mask 8. The tooth rod mounting hole 1c extends in the second direction DR2. The second set screw 10 is configured to enter and exit the tooth rod mounting hole 1c along the third direction DR3 by rotation. The tooth rod 7 is inserted into the tooth rod mounting hole 1c and is used for the mouse to bite with its teeth. The face mask 8 is adjustably mounted on the front end of the tooth rod 7 by means of a fourth set screw 12 and is used to cover the mouse's face in a butting manner. With the help of the tooth rod 7 and the face mask 8, the mouse's body can be better positioned. When the first set screw 9 exits the tooth rod mounting hole 1c, the tooth rod 7 is allowed to move along the second direction DR2. When the second set screw 10 enters the tooth rod mounting hole 1c and abuts against the tooth rod 7 along the third direction DR3, the position of the tooth rod 7 in the second horizontal direction is positioned. In this way, the position of the tooth rod 7 and thus the position of the face mask 8 can be adjusted by rotating the second set screw 10 to adapt to mice of various body types.

[0074] To better fix the mouse's body, the device is further configured with a binding rope (not shown), four binding rope perforations 1d, and four third set screws 11. The binding rope perforations 1d are provided on the base 1 and are located outside the first recess 1a. A part of the binding rope is used to tie the mouse's limbs, and the other part is inserted into the binding rope perforations 1d. The third set screws 11 are configured to be locked into the binding rope perforations 1d by rotation, thereby fixing the other part of the binding rope.

Claims

1. A magnetic resonance coil device for mouse experiments, characterized in that: include: A base, the base having a first depression opening upward, the first depression being used for the mouse to be placed through the opening; a cover, the cover releasably covers at least a portion of the first recess from an upper side and has a second recess opening downward, and when the cover covers the first recess, the first recess and the second recess jointly define an accommodation space for accommodating the mouse; a first coil, the first coil being installed in the base and disposed in the first recess; The second coil is installed in the cover and arranged in the second recess.

2. The device according to claim 1, characterized in that The first recess and the second recess are both formed as arc-shaped recesses.

3. The device according to claim 1, characterized in that The base has: a plurality of latches, the plurality of latches protruding upward from the base outside the first recess; The cover has: A plurality of jacks extending upwardly outside the second recess; The cover is releasably mounted to the base from the upper side by plugging and fitting the plurality of latches into the plurality of sockets.

4. The device according to claim 3, characterized in that By means of friction between the plurality of latches and the plurality of receptacles, the cover can be positioned at a plurality of height positions relative to the base.

5. The device according to claim 1, characterized in that Also includes: An ear bar is adjustably mounted on the base and has a bar head located in the accommodating space, and the bar head is used to abut against the ear of the mouse.

6. The device according to claim 5, characterized in that The cover has a slot extending from an edge of the second recess, and the ear bar extends into the accommodating space via the slot.

7. The device according to claim 6, characterized in that The base has: an ear bar mounting hole, the ear bar mounting hole extending in a first horizontal direction; a first top screw, the first top screw being configured to enter and exit the ear bar mounting hole along a direction intersecting the first horizontal direction by rotating; The ear bars have: a straight line segment, the straight line segment extending along the first horizontal direction and inserted into the ear bar mounting hole; wherein, when the first top screw exits the ear bar mounting hole, the straight line segment is allowed to move along the first horizontal direction and rotate around the first horizontal direction, and when the first top screw enters the ear bar mounting hole and abuts against the straight line segment, the position of the straight line segment in the first horizontal direction and around the first horizontal direction is positioned; A non-straight segment extends from a front end portion of the straight segment toward a front end side, and the front end portion of the non-straight segment constitutes the club head. When viewed along the first horizontal direction, the club head and the straight segment are spaced apart from each other.

8. The device according to claim 7, characterized in that Also includes: A tooth bar mounting hole, wherein the ear bar mounting hole extends in a second horizontal direction perpendicular to the first horizontal direction; a second top screw, the second top screw being configured to enter and exit the tooth bar mounting hole along a direction intersecting the second horizontal direction by rotation; a tooth bar, the tooth bar being inserted into the tooth bar mounting hole for the mouse to bite; when the first top screw exits the tooth bar mounting hole, the tooth bar is allowed to move along the second horizontal direction, and when the first top screw enters the tooth bar mounting hole and abuts against the tooth bar, the position of the tooth bar in the second horizontal direction is positioned; A face mask is mounted on the front end of the tooth bar and is used to cover the face of the mouse in an abutting manner.

9. The device according to claim 8, characterized in that Also includes: A binding rope through hole, the binding rope through hole is provided on the base and is located outside the first recess; A binding rope, a portion of which is used to bind the limbs of the mouse, and another portion of which is inserted into the through hole of the binding rope; A third top screw is configured to be locked into the rope through hole by rotation, thereby releasably engaging the other part of the rope to the rope through hole.

10. The device according to any one of claims 1 to 9, characterized in that The first coil has a shape corresponding to the inner wall surface of the first recess, and covers the back side of the inner wall surface of the first recess; The second coil has a shape corresponding to the inner wall surface of the second recess, and covers the back side of the inner wall surface of the second recess.

Images