Glass slide cleaning assembly and glass slide cleaning device

Abstract

The utility model provides a glass slide cleaning assembly and a glass slide cleaning device, and belongs to the technical field of cleaning devices. The glass slide cleaning assembly comprises a glass slide frame, and a glass slide is inserted into the glass slide frame; the cleaning tank is filled with a flowing cleaning agent; the grabbing piece can grab the slide rack and is movably arranged; the grabbing piece grabs the glass slide frame and moves the glass slide frame into the cleaning tank to be cleaned, and the glass slide frame is moved away from the cleaning tank after the glass slide is cleaned. The glass slide rack is grabbed through the grabbing piece and moved into the cleaning tank to be cleaned, manual operation is reduced, damage caused by manual cleaning of glass slides is avoided, and the physical health of pathological technicians is facilitated.

Description

Technical Field

[0001] The present application belongs to the technical field of slide cleaning devices, and relates to an automatic cleaning device for slides stained by a high-throughput pathology immunohistochemistry instrument, and specifically to a slide cleaning component and a slide cleaning device. Background Art

[0002] Slides are rectangular glass slides that are hard and have good light transmittance. They are usually used by pathology departments to place thin slices of patient specimens and are indispensable experimental consumables for pathology departments. Slides containing thin slices of specimen tissue need to be stained by Roche's fully automatic immunohistochemistry instrument, so that a layer of oil film will be attached to the surface. Therefore, before dehydrating and sealing the slides, the oil film on the surface of the slides needs to be cleaned. Incomplete cleaning will affect the pathologist's interpretation of the color and positioning status of tissue cells under the microscope.

[0003] The current method of cleaning glass slides is to load the glass slides into a slide rack, then place the slide rack in a cleaning agent and repeatedly shake the slide rack to clean the oil film on the surface of the slide, and then rinse it with clean water. First, this process requires manual operation by pathologists, which is cumbersome, time-consuming and labor-intensive, and easily damages the slides. Second, the slides are easy to scratch fingers, and long-term cleaning can be tiring, which also has an adverse effect on the health of pathologists. Third, the phenomenon of unclean cleaning may affect the staining results. Fourth, the efficiency of cleaning the slides is low.

[0004] Therefore, it is necessary to design a slide oil film cleaning device to reduce the operation of pathological technicians. Utility Model Content

[0005] The present application provides an automatic cleaning device for glass slides stained by a high-throughput pathology immunohistochemistry instrument, which specifically includes a glass slide cleaning component and a glass slide cleaning device, and can solve the problem of time-consuming, labor-intensive and inefficient manual cleaning of glass slides in the prior art.

[0006] In order to solve the above problems, the present application provides a slide cleaning assembly, comprising:

[0007] A slide rack, on which a slide glass is inserted;

[0008] a cleaning tank containing a flowing cleaning agent;

[0009] A grabbing member, capable of grabbing the slide rack and being movably arranged;

[0010] The grabbing member grabs the glass slide rack and moves it to the cleaning tank for cleaning, and removes the glass slide rack from the cleaning tank after the glass slide is cleaned.

[0011] In some embodiments,

[0012] A cleaning impeller is arranged in the cleaning tank, and the cleaning impeller drives the cleaning agent to flow in the cleaning tank.

[0013] In some embodiments,

[0014] A heater is provided in the cleaning tank to heat the cleaning agent.

[0015] In some embodiments,

[0016] The slide cleaning assembly also includes a rinsing tank, in which a rinsing impeller and water are arranged; the grabbing member can move the slide rack into the rinsing tank, and the rinsing impeller drives the water to flow, thereby rinsing the slide.

[0017] In some embodiments,

[0018] The grabbing member includes a manipulator and a bracket, the bracket includes a telescopic arm, a first slide bar and a second slide bar, the first slide bar and the second slide bar are cross-arranged when projected on a horizontal plane; the upper end of the telescopic arm is slidably arranged on the first slide bar, and one end of the first slide bar is slidably arranged on the second slide bar; the manipulator is arranged on the lower end of the telescopic arm, and is used to grab the slide rack.

[0019] In some embodiments,

[0020] In the sliding direction along the second slide bar, the cleaning groove and the rinsing groove are arranged side by side in sequence; the slide cleaning assembly also includes two movable grooves, and the two movable grooves are respectively arranged on the outer sides of the cleaning groove and the rinsing groove; the movable groove is arranged to move along the direction intersecting the sliding direction of the second slide bar; the slide rack is placed in the movable groove.

[0021] According to another aspect of the present application, a slide cleaning device is provided, comprising the slide cleaning assembly as described above.

[0022] In some embodiments,

[0023] The slide cleaning device also includes a sealed chamber, in which the slide rack, the cleaning tank and the grabbing member are arranged; and the grabbing member is mounted in the sealed chamber.

[0024] In some embodiments,

[0025] An inlet and an outlet are arranged on the side wall of the sealing chamber. When two movable grooves are arranged, the two movable grooves move out of the sealing chamber respectively through the inlet and the outlet.

[0026] The present application provides a glass slide cleaning assembly, comprising: a glass slide rack, on which a glass slide is inserted; a cleaning tank, in which a flowing cleaning agent is contained; a grabbing member, which can grab the glass slide rack and is movably arranged; the grabbing member grabs the glass slide rack and moves it to the cleaning tank for cleaning, and removes the glass slide rack from the cleaning tank after the glass slide is cleaned.

[0027] This application has the following beneficial effects:

[0028] 1. Grab the slide rack through the grabber and move it to the cleaning tank for cleaning, which reduces manual operation and avoids damage to the slides during manual cleaning, which is beneficial to the health of pathology technicians.

[0029] 2. The use of a grabber to move the slide rack for cleaning can automatically complete the cleaning and improve the efficiency of cleaning the slides. BRIEF DESCRIPTION OF THE DRAWINGS

[0030] In order to more clearly illustrate the implementation methods of the present application or the technical solutions in the prior art, the following is a brief introduction to the drawings required for the implementation methods or the prior art descriptions. The drawings described below are merely exemplary, and for those of ordinary skill in the art, other implementation drawings can be derived from the provided drawings without creative work.

[0031] Figure 1 This is a schematic diagram of the appearance of a glass slide cleaning device according to an embodiment of the present application;

[0032] Figure 2 This is a structural diagram of a glass slide cleaning device according to an embodiment of the present application;

[0033] Figure 3 A schematic diagram of a cleaning structure according to an embodiment of the present application;

[0034] Figure 4 This is a schematic diagram of a loading state of a glass slide in a glass slide cleaning device according to an embodiment of the present application;

[0035] Figure 5 A schematic diagram of the internal structure of a cleaning tank according to an embodiment of the present application;

[0036] Figure 6 This is a schematic diagram of the internal structure of the flushing tank according to an embodiment of the present application;

[0037] Figure 7 This is a schematic diagram of the unloading state of the glass slide of the glass slide cleaning device according to an embodiment of the present application;

[0038] Figure 8 This is a schematic diagram of the structure of a moving tank for unloading a glass slide according to an embodiment of the present application;

[0039] Fig. 9 This is a schematic diagram of the structure of the grabbing member according to an embodiment of the present application.

[0040] The reference numerals are:

[0041] 101. Sealed warehouse;

[0042] 102, first moving slot; 1021, first base; 1022, first guide rail; 1023, first slot body;

[0043] 103, cleaning tank; 1301, cleaning tank body; 1302, cleaning impeller; 1303, cleaning motor; 1304, heating tube;

[0044] 104, flushing tank; 1401, flushing tank body; 1402, flushing dial; 1403, flushing motor;

[0045] 105, second moving slot; 1051, second base; 1052, second guide rail; 1053, second slot body;

[0046] 106, grabbing member; 1061, second sliding bar; 1062, first sliding bar; 1063, telescopic arm; 1064, manipulator. DETAILED DESCRIPTION

[0047] The following will be combined with the drawings in the embodiments of the present application to clearly and completely describe the technical solutions in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all of the embodiments. The following description of at least one exemplary embodiment is actually only illustrative and is by no means intended to limit the present application and its application or use. Based on the embodiments in the present application, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of this application.

[0048] In the description of the present application, it should be understood that the directions or positional relationships indicated by directional words such as "front, back, up, down, left, right", "lateral, vertical, perpendicular, horizontal" and "top, bottom" are usually based on the directions or positional relationships shown in the drawings, and are only for the convenience of describing the present application and simplifying the description. Unless otherwise specified, these directional words do not indicate or imply that the device or element referred to must have a specific direction or be constructed and operated in a specific direction, and therefore cannot be understood as limiting the scope of protection of the present application; the directional words "inside and outside" refer to the inside and outside relative to the contours of each component itself.

[0049] For ease of description, spatially relative terms such as "above", "above", "on the upper surface of", "above", etc. may be used here to describe the spatial positional relationship between a device or feature and other devices or features as shown in the figure. It should be understood that spatially relative terms are intended to include different orientations of the device in use or operation in addition to the orientation described in the figure. For example, if the device in the accompanying drawings is inverted, the device described as "above other devices or structures" or "above other devices or structures" will be positioned as "below other devices or structures" or "below other devices or structures". Thus, the exemplary term "above" can include both "above" and "below". The device can also be positioned in other different ways (rotated 90 degrees or in other orientations), and the spatially relative descriptions used here are interpreted accordingly.

[0050] In addition, it should be noted that the use of terms such as "first" and "second" to limit components is only for the convenience of distinguishing the corresponding components. Unless otherwise stated, the above terms have no special meaning and therefore cannot be understood as limiting the scope of protection of this application.

[0051] See also Figures 1 to 9 As shown, according to an embodiment of the present application, a slide cleaning assembly includes:

[0052] A slide rack, on which a slide glass is inserted;

[0053] A cleaning tank 103 containing a flowing cleaning agent;

[0054] A grabbing member 106, capable of grabbing the slide rack, and being movably arranged;

[0055] The gripping member 106 grips the slide rack and moves it to the cleaning tank 103 for cleaning, and removes the slide rack from the cleaning tank 103 after the slide is cleaned.

[0056] The present application uses a movable gripper 106 to grab the slide rack and move it to the cleaning tank 103 for cleaning, thereby reducing manual operations and avoiding damage to the slides from manual cleaning, which is beneficial to the health of pathologists. At the same time, the entire slide cleaning process can be completed automatically, thereby improving the work efficiency of cleaning the slides.

[0057] In some embodiments,

[0058] A cleaning impeller 1302 is disposed in the cleaning tank 103 , and the cleaning impeller 1302 drives the cleaning agent to flow in the cleaning tank 103 .

[0059] A cleaning wheel is arranged in the cleaning tank 103 to drive the cleaning agent in the cleaning tank 103 to flow, so that the cleaning agent continuously washes the glass slide, thereby achieving effective cleaning and improving the cleaning efficiency.

[0060] In some embodiments,

[0061] The cleaning tank 103 is provided with a heater to heat the cleaning agent.

[0062] A heater, such as a heating tube 1304, is provided in the cleaning tank 103 to heat the cleaning agent and improve the cleaning efficiency.

[0063] In some embodiments,

[0064] The slide cleaning assembly also includes a rinsing tank 104, in which a rinsing impeller and water are arranged; the grabbing member 106 can move the slide rack into the rinsing tank 104, and the rinsing impeller drives the water to flow, thereby rinsing the slide.

[0065] There will be residual cleaning agent on the glass slide after cleaning. The glass slide cleaning assembly of the present application also includes a rinsing tank 104. The cleaned glass slide rack is grabbed by the grabbing member 106, leaves the cleaning tank 103 and moves to the rinsing tank 104 for rinsing; a rinsing dial 1402 and water are provided in the rinsing tank 104. Through the action of the rinsing dial 1402, the flowing water rinses the glass slide, thereby achieving the purpose of washing off the cleaning agent on the surface.

[0066] In some embodiments,

[0067] The grabbing member 106 includes a manipulator 1064 and a bracket, and the bracket includes a telescopic arm 1063, a first slide bar 1062 and a second slide bar 1061, and the first slide bar 1062 and the second slide bar 1061 are cross-arranged when projected on a horizontal plane; the upper end of the telescopic arm 1063 is slidably arranged on the first slide bar 1062, and one end of the first slide bar 1062 is slidably arranged on the second slide bar 1061; the manipulator 1064 is arranged on the lower end of the telescopic arm 1063, and is used to grab the glass slide rack.

[0068] The grabbing member 106 mainly adopts a manipulator 1064 structure arranged on a bracket. The specific structure of the bracket can be composed of three parts. The telescopic arm 1063 can telescopically move. The manipulator 1064 is arranged at the lower end of the telescopic arm 1063. The upper end of the telescopic arm 1063 is slidably arranged on the first slide bar 1062, and the first slide bar 1062 is slidably arranged on the second slide bar 1061. In addition, since the first slide bar 1062 and the second slide bar 1061 are cross-arranged, the bracket as a whole can realize movement in three directions of X, Y and Z.

[0069] In some embodiments,

[0070] In the sliding direction along the second slide bar 1061, the cleaning groove 103 and the rinsing groove 104 are arranged side by side in sequence; the slide cleaning assembly also includes two movable grooves, which are respectively arranged on the outer sides of the cleaning groove 103 and the rinsing groove 104; the movable groove is arranged to move along the direction intersecting the sliding direction of the second slide bar 1061; the slide rack is placed in the movable groove.

[0071] The cleaning tank 103 and the rinsing tank 104 are arranged side by side, and a movable tank is arranged on the outside of each of them: a first movable tank 102 and a second movable tank 105, wherein the first movable tank 102 is located on the outside of the cleaning tank 103, and the second movable tank 105 is located on the outside of the rinsing tank 104, which is equivalent to the first movable tank 102, the cleaning tank 103, the rinsing tank 104 and the second movable tank 105 being arranged side by side; wherein the first movable tank 102 and the second movable tank 105 are movable, and the slide can be moved out of or into the movable tank by the grabbing member 106.

[0072] In actual operation, the glass slide rack is placed in the first movable groove 102, so that the first movable groove 102 moves to the outside of the cleaning groove 103, so that the grabbing member 106 can easily grab the glass slide rack from the first movable groove 102, and send it into the cleaning groove 103 for cleaning after taking it out. After cleaning and rinsing, the glass slide rack is sent into the second movable groove 105 by the grabbing member 106, and the second movable groove 105 is moved to facilitate the removal of the clean slide.

[0073] According to another aspect of the present application, a slide cleaning device is provided, comprising the slide cleaning assembly as described above.

[0074] The slide cleaning device using the above slide cleaning assembly can reduce manual operations during the cleaning and rinsing of slides, improve cleaning efficiency, reduce damage to slides caused by manual cleaning, and is beneficial to the health of pathology technicians.

[0075] In some embodiments,

[0076] The slide cleaning device further comprises a sealed chamber 101 , wherein the slide rack, the cleaning tank 103 and the grabbing member 106 are arranged in the sealed chamber 101 ; and the grabbing member 106 is mounted in the sealed chamber 101 .

[0077] The slide cleaning device adopts a sealed chamber 101 structure, and the cleaning tank 103 and the grabbing member 106 are sealed, so that the entire slide cleaning process is carried out in the sealed chamber 101 to reduce pollution.

[0078] In some embodiments,

[0079] An inlet and an outlet are provided on the side wall of the sealed chamber 101. When two movable grooves are provided, the two movable grooves move out of the sealed chamber 101 respectively through the inlet and the outlet.

[0080] An inlet and an outlet are arranged on the side wall of the sealed chamber 101, so as to facilitate entry and exit of the first movable groove 102 and the second movable groove 105. Specifically, the first movable groove 102 is entered and exited via the inlet, and the second movable groove 105 is entered and exited via the outlet. Before cleaning, the first movable groove 102 is pulled out from the inlet, and a slide rack for placing a glass slide is placed into the first movable groove 102, and then the first movable groove 102 is pushed into the sealed chamber 101. The grabbing part 106 grabs and moves the slide rack for cleaning and rinsing, and finally moves to the second movable groove 105, places the slide rack in the second movable groove 105, and pulls the second movable groove 105 out from the outlet to obtain a clean glass slide.

[0081] The slide cleaning device of the present application injects tap water and cleaning agent into the cleaning tank 103 before cleaning and heats it in a water bath. The bottom cleaning impeller 1302 rotates under the action of the driving motor, thereby driving the water flow to clean the slide and achieve the purpose of cleaning.

[0082] After cleaning, the slides need to be rinsed. The gripping robot 1064 transports the slide rack to the rinse tank 104 for rinsing with tap water to wash away the detergent on the slides. This replaces manual cleaning, saves time and effort, and the cleaning effect of the slides is guaranteed. After rinsing, the slides can be placed in the unloading room.

[0083] The first movable tank 102 is used to place the slides and slide racks to be cleaned. The first movable tank 102 is composed of a first base 1021, a first guide rail 1022 and a first tank body 1023. The first base 1021 is used to support and install related materials, the first guide rail 1022 is used for the movement of the first tank body 1023, and the first tank body 1023 is used to place the slides and slide racks.

[0084] The cleaning tank 103 is provided with a water bath heating and a cleaning impeller 1302, and correspondingly, there are also a clean water injection port, a sewage outlet and a cleaning agent injection port. The cleaning impeller 1302 rotates to drive the water flow to clean the slide. The cleaning tank 103 is composed of a cleaning tank 103 body, a cleaning impeller 1302, a driving motor 1303, and a heating tube 1304. The cleaning tank 103 body is used to install related components and is provided with a clean water injection port, a sewage outlet and a cleaning agent injection port. The cleaning impeller 1302 is used to drive the water flow to achieve the purpose of cleaning. The driving motor 1303 drives the cleaning impeller 1302 to rotate through a belt. The heating tube 1304 is used to heat clean water.

[0085] The washing tank 104 is used to wash the cleaning agent remaining on the slide, and the washing tank 104 is provided with a clean water injection port and a sewage outlet. The washing tank 104 is composed of a washing tank 104 body, a washing impeller 1402, and a washing motor 1403. The washing impeller 1402 is used to drive the water flow to achieve the purpose of washing. The washing motor 1403 drives the washing impeller to rotate through a belt.

[0086] The second movable tank 105 is used to unload the slide rack and has the functions of hygiene and safety protection. The second movable tank 105 is composed of a second base 1051, a second guide rail 1052, and a second tank body 1053. The second base 1051 is used to support and install related materials, the second guide rail 1052 is used for the movement of the second tank body 1053, and the slide rack is placed in the second tank body 1053.

[0087] The gripper 106 is used to transfer the slide rack between the functional positions such as the first moving tank 102, the cleaning tank 103, the rinsing tank 104 and the second moving tank 105. The gripper 106 is composed of a manipulator 1064, a telescopic arm 1063, a first slide bar 1062 and a second slide bar 1061, wherein the second slide bar 1061 moves along the X-axis, the first slide bar 1062 moves along the Y-axis, and the telescopic arm 1063 moves along the Z-axis; the manipulator 1064 is assembled on the telescopic arm 1063, so as to realize the movement of the gripper 106 in multiple directions.

[0088] Before cleaning the glass slide, it is necessary to connect to the power supply and water source. When cleaning, open the left slot door (i.e., the inlet) of the sealed chamber 101, pull out the first slot body 1023, load the glass slide rack to be cleaned and push it into the original position, the grabbing member 106 executes the grabbing command, grabs the glass slide rack and transports the glass slide rack to the cleaning tank 103, the cleaning tank 103 executes the cleaning command to inject tap water and cleaning agent and use water bath heating, the cleaning impeller 1302 at the bottom of the cleaning tank 103 rotates to drive the water flow to clean the glass slide, so as to achieve the purpose of cleaning. After the cleaning is completed, the grabbing member 106 executes the grabbing command, grabs the glass slide rack and transports it to the rinsing tank 104, and executes the rinsing command in the rinsing tank 104 to rinse with clean water, so as to achieve the purpose of washing the cleaning agent on the glass slide. After the rinsing is completed, the grabbing member 106 executes the grabbing command, grabs the glass slide rack and transports it to the second slot body 1053. At this time, the right slot door (i.e., the outlet) of the sealed chamber 101 can be opened, and the cleaned glass slide rack can be unloaded to proceed to the next step.

[0089] The cleaning tank 103 and the rinsing tank 104 can be calibrated for time setting according to the actual cleanliness, so as to finally achieve the purpose of cleaning a clean slide.

[0090] It is easy for those skilled in the art to understand that the above-mentioned implementation modes can be freely combined and superimposed without conflict.

[0091] The above is only a preferred embodiment of the present application and is not intended to limit the present application. Any modifications, equivalent replacements and improvements made within the spirit and principles of the present application shall be included in the protection scope of the present application. The above is only a preferred implementation of the present application. It should be pointed out that for ordinary technicians in this technical field, several improvements and variations can be made without departing from the technical principles of the present application, and these improvements and variations should also be regarded as the protection scope of the present application.

Claims

1. A slide cleaning assembly, characterized in that: include: A slide rack, on which a slide glass is inserted; a cleaning tank (103) containing a flowing cleaning agent; A grabbing member (106) capable of grabbing the slide rack and being movably arranged; The grabbing member (106) grabs the glass slide rack and moves it to the cleaning tank (103) for cleaning, and after the glass slide is cleaned, the glass slide rack is removed from the cleaning tank (103).

2. The slide cleaning assembly according to claim 1, characterized in that: A cleaning impeller (1302) is provided in the cleaning tank (103), and the cleaning impeller (1302) drives the cleaning agent to flow in the cleaning tank (103).

3. The slide cleaning assembly according to claim 1 or 2, characterized in that: A heater is provided in the cleaning tank (103) to heat the cleaning agent.

4. The slide cleaning assembly according to claim 1, characterized in that: The glass slide cleaning assembly also includes a rinsing tank (104), in which a rinsing impeller and water are arranged; the grabbing member (106) can move the glass slide rack into the rinsing tank (104), and the rinsing impeller drives the water to flow, thereby rinsing the glass slide.

5. The slide cleaning assembly according to claim 4, characterized in that: The grabbing member (106) comprises a manipulator (1064) and a bracket, wherein the bracket comprises a telescopic arm (1063), a first slide bar (1062) and a second slide bar (1061), wherein the first slide bar (1062) and the second slide bar (1061) are cross-arranged when projected on a horizontal plane; the upper end of the telescopic arm (1063) is slidably disposed on the first slide bar (1062), and one end of the first slide bar (1062) is slidably disposed on the second slide bar (1061); the manipulator (1064) is disposed on the lower end of the telescopic arm (1063) and is used to grab the slide rack.

6. The slide cleaning assembly according to claim 5, characterized in that: In the sliding direction along the second slide bar (1061), the cleaning groove (103) and the rinsing groove (104) are arranged side by side in sequence; the slide cleaning assembly also includes two movable grooves, and the two movable grooves are respectively arranged on the outer sides of the cleaning groove (103) and the rinsing groove (104); the movable groove is arranged to move along the direction intersecting the sliding direction of the second slide bar (1061); the slide rack is placed in the movable groove.

7. A slide cleaning device, characterized in that: It comprises a slide cleaning assembly as described in any one of claims 1-6.

8. The slide cleaning device according to claim 7, characterized in that: The slide cleaning device further comprises a sealed chamber (101), wherein the slide rack, the cleaning tank (103) and the grabbing member (106) are arranged in the sealed chamber (101); and the grabbing member (106) is mounted in the sealed chamber (101).

9. The slide cleaning device according to claim 8, characterized in that: An inlet and an outlet are provided on the side wall of the sealed chamber (101); when two movable grooves are provided, the two movable grooves move out of the sealed chamber (101) via the inlet and the outlet respectively.

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