Circulating adsorption device for urokinase

Abstract

The utility model relates to the field of urokinase, and discloses a urokinase cyclic adsorption device which comprises a tank body, a filter barrel is inserted into the inner wall of the tank body, the front end of the filter barrel is fixedly connected with a handle, a fixing assembly is arranged on the outer wall of the tank body, the fixing assembly comprises a fixing block, and the fixing block is fixedly connected with the filter barrel. The right end of the fixing block is fixedly connected to the left end of the tank body, a pressing plate is hinged to the top end of the fixing block, a stirring assembly is arranged at the top end of the pressing plate and comprises a sliding plate, the sliding plate slides on the inner wall of the pressing plate, a motor is installed at the top end of the sliding plate, and a stirring rod is fixedly connected to the bottom end of an output shaft of the motor. And a drainage pipe is mounted at the bottom end of the tank body. According to the utility model, the filter barrel is arranged inside the tank body, after one-time adsorption is completed, a sample does not need to be discharged out of the tank body, the resin can be replaced only by taking out the filter barrel, and the pressing plate can extrude the top end of the filter screen to prevent the filter screen from randomly moving.

Description

Technical Field

[0001] The utility model relates to the field of urokinase, in particular to a urokinase circulating adsorption device. Background Technique

[0002] Urokinase is an enzyme protein isolated from the urine of healthy people or obtained from the tissue culture of human kidneys. Urokinase has the function of dissolving thrombus. It can activate the plasminogen in the body to be converted into plasmin, thereby degrading fibrin clots and dissolving thrombus. In the prior art, resin adsorption is generally used to collect urokinase in urine.

[0003] When adsorbing urokinase, in order to ensure that the urokinase inside the sample can be completely adsorbed, multiple cyclic adsorptions are generally required. However, in the prior art, a filter screen is generally arranged at the drainage port. After one adsorption is completed, the sample needs to be completely discharged from the inside of the stirring barrel to another stirring barrel. During the process of transferring the sample, multiple groups of stirring barrels need to be prepared and there may be omissions when transferring the sample. The overall device is inconvenient to use. Therefore, a urokinase circulating adsorption device is proposed to solve the above problems. Content of the Utility Model

[0004] In order to make up for the above deficiencies, the utility model provides a urokinase circulating adsorption device, aiming to improve the problem of "using multiple groups of stirring barrels to realize the cyclic adsorption of samples, multiple groups of stirring barrels need to be prepared and there may be omissions when transferring samples" in the prior art.

[0005] In order to achieve the above purpose, the utility model adopts the following technical scheme: a urokinase circulating adsorption device, including a tank body, a filter barrel is inserted into the inner wall of the tank body, a handle is fixedly connected to the front end of the filter barrel, a fixing component is arranged on the outer wall of the tank body, the fixing component includes a fixing block, the right end of the fixing block is fixedly connected to the left end of the tank body, a pressing plate is hinged to the top of the fixing block, a stirring component is arranged on the top of the pressing plate, the stirring component includes a sliding plate, the sliding plate slides inside the pressing plate, a motor is installed on the top of the sliding plate, the bottom end of the output shaft of the motor is fixedly connected to a stirring rod, and a drain pipe is installed at the bottom end of the tank body.

[0006] As a further description of the above technical solution:

[0007] The stirring component further includes a turning handle, the rear end of the turning handle is fixedly connected to the front end of the sliding plate, and the turning handle penetrates and is slidably connected to the front end of the pressing plate.

[0008] As a further description of the above technical solution:

[0009] A sliding rod is slidably connected to the inner wall of the dial handle. Positioning blocks are fixedly connected to both the top end and the bottom end of the sliding rod. A positioning groove is provided at the front end of the pressing plate, and the positioning groove is adapted to the positioning block.

[0010] As a further description of the above technical solution:

[0011] A positioning spring is fixedly connected to the front end of the sliding rod, and the front end of the positioning spring is fixedly connected to the inner wall of the motor.

[0012] As a further description of the above technical solution:

[0013] Multiple groups of the positioning blocks are provided, and the multiple groups of positioning blocks are symmetrically arranged with the center line of the sliding rod as the axis of symmetry.

[0014] As a further description of the above technical solution:

[0015] The fixing assembly further includes a first rack, the first rack is slidably connected to the inner wall of the pressing plate, the left end of the first rack is fixedly connected to the right end of the sliding plate, and a gear is meshed with the front end of the first rack.

[0016] As a further description of the above technical solution:

[0017] The gear is rotatably connected to the inner wall of the pressing plate, a second rack is meshed with the front end of the gear, and a clamping block is fixedly connected to the right end of the second rack.

[0018] As a further description of the above technical solution:

[0019] A convex block is fixedly connected to the right end of the tank body, and the convex block is adapted to the clamping block.

[0020] The utility model has the following beneficial effects:

[0021] 1. In the utility model, by arranging the filter barrel inside the tank body, after one adsorption is completed, it is not necessary to discharge the sample from the tank body. Only by taking out the filter barrel can the resin be replaced, and the pressing plate will press against the top of the filter screen to prevent it from moving randomly. The overall device is more convenient to use.

[0022] 2. In the utility model, by using the sliding plate to drive the whole stirring assembly to move, the operator can conveniently rotate the pressing plate to drive the stirring rod out of the inside of the tank body. In this way, a longer stirring rod can be selected for stirring, so as to achieve a better stirring effect. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] Figure 1 It is a three-dimensional structural schematic diagram of the whole device in the utility model;

[0024] Figure 2Schematic cross-sectional view of the overall device in the present utility model;

[0025] Figure 3 Schematic cross-sectional view of the fixing component in the present utility model;

[0026] Figure 4 In the present utility model Figure 3 Enlarged schematic three-dimensional structure view of part A.

[0027] Legend description:

[0028] 1. Tank body; 2. Filter barrel; 3. Handle; 4. Fixing component; 41. Fixing block; 42. Pressing plate; 43. Clamping block; 44. Convex block; 45. First rack; 46. Gear; 47. Second rack; 5. Stirring component; 51. Motor; 52. Slide plate; 53. Stirring rod; 54. Pushing handle; 55. Slide rod; 56. Positioning groove; 57. Positioning block; 58. Positioning spring; 6. Drain pipe. Specific implementation manner

[0029] Next, the technical solutions in the embodiments of the present utility model will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present utility model. Obviously, the described embodiments are only a part of the embodiments of the present utility model, rather than all the embodiments. Based on the embodiments in the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present utility model.

[0030] Refer to Figure 1 - Figure 3 , an embodiment provided by the present utility model: A urokinase circulation adsorption device, including a tank body 1 for accommodating a sample, a filter barrel 2 for filtering resin is inserted into the inner wall of the tank body 1, a handle 3 for facilitating the operator to move the filter barrel 2 is fixedly connected to the front end of the filter barrel 2, a fixing component 4 for fixing the filter barrel 2 is arranged on the outer wall of the tank body 1, the fixing component 4 includes a fixing block 41 for supporting the overall fixing component 4, the right end of the fixing block 41 is fixedly connected to the left end of the tank body 1, a pressing plate 42 for pressing and fixing the filter barrel 2 is hinged to the top of the fixing block 41, a stirring component 5 for stirring the liquid inside the tank body 1 is arranged at the top of the pressing plate 42, the stirring component 5 includes a slide plate 52 for driving the motor 51 to move, the slide plate 52 slides on the inner wall of the pressing plate 42, a motor 51 for providing power for stirring is installed at the top of the slide plate 52, the bottom end of the output shaft of the motor 51 is fixedly connected to a stirring rod 53 for stirring the liquid, both the motor 51 and the stirring rod 53 are existing technologies, and the power supply can be connected to start working. Due to the existing technology and can be realized by those skilled in the art, so this case will not describe too much about the bottom end of the tank body 1 is installed with a drain pipe 6 for discharging the sample.

[0031] Reference Figure 2 - Figure 4 The stirring assembly 5 also includes a lever 54 for facilitating the operator to move the slide plate 52. The rear end of the lever 54 is fixedly connected to the front end of the slide plate 52. The slide plate 52 can be driven to move left and right by moving the lever 54 left and right. The lever 54 penetrates and is slidably connected to the front end of the pressing plate 42. When the lever 54 and the pressing plate 42 are in a connected state, the pressing plate 42 can also be driven to rotate by moving the lever 54. The inner wall of the lever 54 is slidably connected to a slide bar 55 for driving the positioning block 57 to move. The top and bottom ends of the slide bar 55 are fixedly connected to a positioning block 57 for connecting the slide bar 55 and the pressing plate 42. 7. The front end of the pressure plate 42 is provided with a positioning groove 56 for accommodating the positioning block 57. The positioning groove 56 and the positioning block 57 are adapted to each other. When the positioning block 57 is inserted into the positioning groove 56, the slide bar 55 and the pressure plate 42 will be connected. The front end of the slide bar 55 is fixedly connected with a positioning spring 58 for supporting the slide bar 55. The front end of the positioning spring 58 is fixedly connected to the inner wall of the motor 51. The positioning spring 58 will always push the slide bar 55 backward to prevent it from moving forward at will. There are multiple groups of positioning blocks 57, and the multiple groups of positioning blocks 57 are symmetrically arranged with the center line of the slide bar 55 as the symmetry axis.

[0032] Reference Figure 1 - Figure 3 The fixed assembly 4 also includes a rack 45 for driving the gear 46 to rotate. The rack 45 is slidably connected to the inner wall of the pressure plate 42. The rack 45 can slide left and right on the inner wall of the pressure plate 42 but cannot rotate. The left end of the rack 45 is fixedly connected to the right end of the slide plate 52. When the slide plate 52 moves left and right, the rack 45 will also be driven to move synchronously. The front end of the rack 45 is engaged with a gear 46 for connecting the rack 45 and the rack 2 47. The gear 46 is rotatably connected to the inner wall of the pressure plate 42, and the front end of the gear 46 is meshed with a rack 2 47 for driving the block 43 to move. The right end of the rack 2 47 is fixedly connected to the block 43 for fixing the pressure plate 42, and the right end of the tank body 1 is fixedly connected to a protrusion 44 for cooperating with the block 43 to fix the pressure plate 42. The protrusion 44 and the block 43 are adapted to each other, and the block 43 is set to be L-shaped. The pressure plate 42 can be fixed by using the block 43 to hook the protrusion 44.

[0033] Working principle: when filtering is required, the filter barrel 2 must be placed inside the tank body 1 first, and then the drain pipe 6 must be closed. Then the sample and resin can be placed inside the tank body 1, and then the pressing plate 42 can be rotated to place it horizontally on the top of the filter barrel 2, and then the slide bar 55 can be pushed forward to drive the positioning block 57 to disengage from the inside of the positioning groove 56, and then the motor 51 can be moved to the right to drive the slide plate 52 to move to the right, and the movement of the slide plate 52 to the right will drive the rack 1 45 to move to the right synchronously, and the rack 1 45 will drive the gear 46 to rotate, and the rotation of the gear 46 will drive the rack 2 47 to move to the left, and the movement of the rack 2 47 to the left will pull the block 43 to hook the protrusion 44, and the pressing plate 42 will be fixed, and then the slide bar 55 can be released, and the positioning spring 58 will push the slide bar 55 to move backward, and the movement of the slide bar 55 backward will drive the positioning block 57 to re-enter the inside of the positioning groove 56, and the motor 51 will also be re-fixed, and then the motor 51 can be started to start the stirring operation.

[0034] When the stirring is completed and secondary circulation adsorption is required, the pressure plate 42 can be reopened in the order of installing the filter barrel 2, and then the filter barrel 2 can be taken out. The filter barrel 2 will drive the resin inside the tank body 1 to be separated from the tank body 1, and then the resin inside the filter barrel 2 can be poured out, and then the filter barrel 2 can be put back into the tank body 1 and resin can be added for secondary circulation adsorption.

[0035] Finally, it should be noted that the above is only a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art can still modify the technical solutions described in the aforementioned embodiments or make equivalent substitutions for some of the technical features therein. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A urokinase circulation adsorption device, comprising a tank (1), characterized in that: A filter barrel (2) is inserted into the inner wall of the tank body (1), and a handle (3) is fixedly connected to the front end of the filter barrel (2). A fixing assembly (4) is arranged on the outer wall of the tank body (1), and the fixing assembly (4) comprises a fixing block (41). The right end of the fixing block (41) is fixedly connected to the left end of the tank body (1). A pressing plate (42) is hingedly connected to the top of the fixing block (41). A stirring assembly (5) is arranged at the top of the pressing plate (42). The stirring assembly (5) comprises a slide plate (52). The slide plate (52) slides on the inner wall of the pressing plate (42). A motor (51) is installed at the top of the slide plate (52). A stirring rod (53) is fixedly connected to the bottom end of the output shaft of the motor (51). A drain pipe (6) is installed at the bottom end of the tank body (1).

2. A urokinase circulation adsorption device according to claim 1, characterized in that: The stirring assembly (5) further comprises a handle (54), the rear end of which is fixedly connected to the front end of the slide plate (52), and the handle (54) penetrates through and is slidably connected to the front end of the pressing plate (42).

3. A urokinase circulation adsorption device according to claim 2, characterized in that: The inner wall of the lever (54) is slidably connected to a slide rod (55), the top and bottom ends of the slide rod (55) are fixedly connected to positioning blocks (57), the front end of the pressure plate (42) is provided with a positioning groove (56), and the positioning groove (56) and the positioning block (57) are matched.

4. A urokinase circulation adsorption device according to claim 3, characterized in that: The front end of the slide rod (55) is fixedly connected to a positioning spring (58), and the front end of the positioning spring (58) is fixedly connected to the inner wall of the motor (51).

5. The urokinase circulation adsorption device according to claim 4, characterized in that: The positioning blocks (57) are provided in multiple groups, and the multiple groups of positioning blocks (57) are symmetrically arranged with the center line of the slide bar (55) as the symmetry axis.

6. The urokinase circulation adsorption device according to claim 1, characterized in that: The fixing assembly (4) further comprises a rack (45), wherein the rack (45) is slidably connected to the inner wall of the pressure plate (42), the left end of the rack (45) is fixedly connected to the right end of the slide plate (52), and the front end of the rack (45) is meshed with a gear (46).

7. A urokinase circulation adsorption device according to claim 6, characterized in that: The gear (46) is rotatably connected to the inner wall of the pressure plate (42), the front end of the gear (46) is meshed with a rack 2 (47), and the right end of the rack 2 (47) is fixedly connected with a clamping block (43).

8. The urokinase circulation adsorption device according to claim 7, characterized in that: A convex block (44) is fixedly connected to the right end of the tank body (1), and the convex block (44) is matched with the clamping block (43).

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