Degassing system for vaccine production

Abstract

The utility model provides a degassing system for vaccine production, which comprises a degassing tank, the top of the degassing tank is connected with a gas inlet pipe and a gas outlet pipe, and the bottom of the degassing tank is connected with a liquid inlet pipe and a liquid outlet pipe; an air inlet control valve is arranged on the air inlet pipe, an exhaust control valve is arranged on the exhaust pipe, a liquid inlet control valve is arranged on the liquid inlet pipe, a liquid discharge control valve is arranged on the liquid discharge pipe, the air inlet control valve is further provided with a steam inlet, and a steam input pipe is connected to the steam inlet. According to the utility model, reliable degassing can be carried out, and the degassing tank and each pipeline can be fully and comprehensively disinfected before liquid is introduced.

Description

Technical Field

[0001] The utility model belongs to the technical field of vaccine production, and particularly relates to a degassing system for vaccine production. Background Art

[0002] A wide variety of liquids are required in the vaccine production process. For example, purified water, water for injection, etc. Inevitably, air is mixed into the liquid during the injection of the liquid into the system. It exists in the liquid in the form of tiny bubbles, which affects the accurate measurement of the liquid volume (such as volume), directly affects the subsequent production, and also has negative effects such as oxidation and corrosion on the equipment, increasing the maintenance cost and reducing the service life of the equipment. There are some existing degassing devices for degassing liquids, but these devices have complex structures, there are many sanitary dead corners, and bacteria are likely to breed, contaminating the liquid in the equipment and directly affecting the subsequent production process. Summary of the Utility Model

[0003] An embodiment of the utility model provides a degassing system for vaccine production, aiming to solve the problem that the existing degassing devices for degassing liquids are difficult to disinfect comprehensively and are prone to breed harmful substances such as bacteria inside the devices.

[0004] To achieve the above object, the technical solution adopted by the utility model is:

[0005] Provide a degassing system for vaccine production, including:

[0006] A degassing tank, the top of the degassing tank is connected with an inlet pipe and an exhaust pipe, and the bottom is connected with an inlet liquid pipe and a drain pipe;

[0007] An intake control valve is provided on the inlet pipe, an exhaust control valve is provided on the exhaust pipe, an inlet liquid control valve is provided on the inlet liquid pipe, a drain control valve is provided on the drain pipe, and the intake control valve further has a steam inlet, and a steam input pipe is connected to the steam inlet.

[0008] In a possible implementation manner, a high liquid level sensor and a low liquid level sensor located below the high liquid level sensor are provided on the degassing tank, and the liquid inlet end of the drain pipe is lower than the low liquid level sensor.

[0009] In some embodiments, the liquid inlet port of the drain pipe is located on the bottom wall of the degassing tank.

[0010] In some embodiments, the liquid outlet end of the inlet liquid pipe is higher than the low liquid level sensor and lower than the high liquid level sensor.

[0011] In some embodiments, a pressure sensor is provided inside the degassing tank, and the pressure sensor is higher than the high liquid level sensor.

[0012] In a possible implementation, a filter is connected to the outlet side of the exhaust control valve.

[0013] In some embodiments, an exhaust transition pipe is connected between the exhaust control valve and the filter.

[0014] In a possible implementation, the liquid inlet control valve further has a first discharge port, and a first exhaust pipe for discharging steam is connected to the first discharge port.

[0015] In a possible implementation, the liquid discharge control valve further has a second discharge port, and a second exhaust pipe for discharging steam is connected to the second discharge port.

[0016] In a possible implementation, the intake control valve further has a main intake port and a main outlet port. The main intake port is connected to an intake transition pipe, and the intake pipe is connected between the main outlet port and the degassing tank.

[0017] The solution shown in the embodiments of the present application has the following beneficial effects compared with the prior art:

[0018] 1) When degassing is required, the degassing tank itself can achieve the degassing function. The liquid inlet control valve is opened to allow the liquid to enter the degassing tank from the liquid inlet pipe. During the rising process of the liquid level, the exhaust control valve is opened to ensure normal pressure in the degassing tank and enable normal liquid inlet. After the liquid level reaches a certain height, first close the exhaust control valve, and then close the liquid inlet control valve. The degassing tank starts to degas. After degassing is completed, the exhaust control valve is reopened to discharge the gas. At the same time, the liquid discharge control valve is opened to discharge the gas released from the liquid. The liquid volume can be accurately measured. Finally, it is beneficial to accurately convey a specified amount of liquid to the subsequent production equipment. If the air pressure in the degassing tank is too low after the exhaust control valve is closed, resulting in a continuous rise in the liquid level and affecting the accurate quantification of the liquid volume in the degassing tank, then open the intake control valve to convey a certain amount of sterile gas (such as sterile air) into the degassing tank (above the liquid), maintain the air pressure balance in the degassing tank, avoid the liquid level in the degassing tank from being too high, and maintain the reliability of use.

[0019] 2) When disinfection is required, open the intake control valve, exhaust control valve, liquid inlet control valve, and liquid discharge control valve. The steam enters the degassing tank successively through the intake control valve and the intake pipe through the steam input pipe. After filling the inner cavity of the degassing tank, with continuous steam input, the steam will also enter the exhaust pipe, liquid inlet pipe, and liquid discharge pipe. Finally, the intake pipe, exhaust pipe, liquid inlet pipe, liquid discharge pipe, and degassing tank can all be steam disinfected, and the steam can effectively contact the dead corners that are not easily disinfected in the above-mentioned various components. Compared with the traditional method of disinfecting with disinfectant solution, the disinfection is more comprehensive and thorough. Description of the Drawings

[0020] Figure 1 Schematic diagram of the degassing system for vaccine production provided in the first embodiment of the present utility model;

[0021] Figure 2 Schematic diagram of the degassing system for vaccine production provided in the second embodiment of the present utility model;

[0022] Figure 3 Schematic diagram of the degassing system for vaccine production provided in the third embodiment of the present utility model;

[0023] Figure 4 Schematic diagram of the degassing system for vaccine production provided in the fourth embodiment of the present utility model;

[0024] Figure 5 Schematic diagram of the degassing system for vaccine production provided in the fifth embodiment of the present utility model;

[0025] Figure 6 Schematic diagram of the installation groove body adopted in the sixth embodiment of the present utility model;

[0026] Figure 7 Assembly diagram of the air pressure sensor adopted in the seventh embodiment of the present utility model;

[0027] Explanation of reference numerals:

[0028] 1. Degassing tank; 101. Transparent viewing window; 110. Main tank body; 120. Degassing device; 121. Driver; 122. Disturbing blade; 123. Heater; 124. Ultrasonic generator; 125. Helium inlet pipe; 126. Air outlet tray; 2. Inlet pipe; 3. Exhaust pipe; 4. Inlet liquid pipe; 5. Drainage pipe; 6. Inlet air control valve; 7. Exhaust control valve; 8. Inlet liquid control valve; 9. Drainage control valve; 10. Steam input pipe; 11. High liquid level sensor; 12. Low liquid level sensor; 13. Installation groove body; 1301. Cable accommodation notch; 14. Air pressure sensor; 15. Protection box; 1510. Box body; 1520. Cover body; 16. First sealing gasket; 17. Second sealing gasket; 18. Pressure ring; 19. Sealing ring; 20. Filter; 21. Exhaust transition pipe; 22. First exhaust pipe; 23. Second exhaust pipe; 24. Inlet air transition pipe. Detailed implementation manners

[0029] In order to make the technical problems, technical solutions and beneficial effects to be solved by the present utility model clearer and more understandable, the present utility model will be further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present utility model and are not used to limit the present utility model.

[0030] In the claims, description and the above-mentioned drawings of the present utility model, unless otherwise clearly defined, when using terms such as "first", "second" or "third", etc., they are used to distinguish different objects rather than to describe a specific order.

[0031] In the claims, description and the above-mentioned drawings of the present utility model, unless otherwise clearly defined, for orientation terms, when using terms such as "center", "lateral", "longitudinal", "horizontal", "vertical", "top", "bottom", "inner", "outer", "upper", "lower", "front", "rear", "left", "right", "clockwise", "counterclockwise", "high", "low", etc. to indicate the orientation or positional relationship, it is based on the orientation and positional relationship shown in the drawings, and is only for the convenience of describing the present utility model and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation or be constructed and operated in a specific orientation, so it cannot be understood as limiting the specific protection scope of the present utility model.

[0032] In the claims, description and the above-mentioned drawings of the present utility model, unless otherwise clearly defined, when using the terms "fixed connection" or "fixedly connected", it should be understood in a broad sense, that is, any connection method without displacement relationship and relative rotation relationship between the two, that is, including non-detachable fixed connection, detachable fixed connection, being integrally connected and being fixed connected through other devices or elements.

[0033] In the claims, description and the above-mentioned drawings of the present utility model, when using terms such as "comprising", "having" and their variants, the intention is "including but not limited to".

[0034] Please refer to Figures 1 to 5 , and now the degassing system for vaccine production provided by the present utility model will be described. The degassing system for vaccine production includes a degassing tank 1. An air inlet pipe 2 and an exhaust pipe 3 are connected to the top of the degassing tank 1, and a liquid inlet pipe 4 and a liquid discharge pipe 5 are connected to the bottom; an air inlet control valve 6 is provided on the air inlet pipe 2, an exhaust control valve 7 is provided on the exhaust pipe 3, a liquid inlet control valve 8 is provided on the liquid inlet pipe 4, a liquid discharge control valve 9 is provided on the liquid discharge pipe 5, and the air inlet control valve 6 further has a steam inlet, and a steam input pipe 10 is connected to the steam inlet.

[0035] In this embodiment, the air inlet control valve 6, the exhaust control valve 7, the liquid inlet control valve 8 and the liquid discharge control valve 9 are all solenoid valves, which can be obtained by purchase and only need to meet the function of adjusting the flow passage according to different flow requirements, and the specific structure will not be elaborated here.

[0036] The degassing system for vaccine production provided by this embodiment has the following beneficial effects compared with the prior art:

[0037] 1) When degassing is required, the degassing tank 1 can achieve the degassing function by itself. The liquid inlet control valve 8 is opened to allow the liquid to enter the degassing tank 1 from the liquid inlet pipe 4. During the rising of the liquid level, the exhaust control valve 7 is opened to ensure normal pressure in the degassing tank 1 and normal liquid inlet. After the liquid level reaches a certain height, first close the exhaust control valve 7, and then close the liquid inlet control valve 8. The degassing tank 1 starts to degas. After degassing is completed, the exhaust control valve 7 is reopened to discharge the gas. At the same time, the liquid discharge control valve 9 is opened to discharge the gas released from the liquid. The liquid volume can be accurately measured. Finally, it is beneficial to accurately convey a specified amount of liquid to the subsequent production equipment. If the air pressure in the degassing tank 1 is too low after the exhaust control valve 7 is closed, resulting in the continuous rise of the liquid level and affecting the accurate quantification of the liquid volume in the degassing tank 1, the air inlet control valve 6 is opened to convey a certain amount of sterile gas (such as sterile air) into the degassing tank 1 (above the liquid) to maintain the air pressure balance in the degassing tank 1, avoid the liquid level in the degassing tank 1 being too high, and maintain the reliability of use.

[0038] 2) When disinfection is required, the air inlet control valve 6, the exhaust control valve 7, the liquid inlet control valve 8 and the liquid discharge control valve 9 are opened. Steam enters the degassing tank 1 successively through the air inlet control valve 6 and the air inlet pipe 2 through the steam input pipe 10. After filling the inner cavity of the degassing tank 1, with continuous steam input, the steam will also enter the exhaust pipe 3, the liquid inlet pipe 4 and the liquid discharge pipe 5. Eventually, the air inlet pipe 2, the exhaust pipe 3, the liquid inlet pipe 4, the liquid discharge pipe 5 and the degassing tank 1 can all be steam disinfected, and the steam can effectively contact the dead corners that are not easily disinfected in the above-mentioned various components. Compared with the traditional method of disinfecting with disinfectant solution, the disinfection is more comprehensive and thorough.

[0039] In some embodiments, refer to Figures 1 to 5A high liquid level sensor 11 and a low liquid level sensor 12 located below the high liquid level sensor 11 are provided on the degassing tank 1, and the liquid inlet end of the discharge pipe 5 is lower than the low liquid level sensor 12, wherein the high liquid level sensor 11 is communicatively connected with the liquid inlet control valve 8, the exhaust control valve 7 and the air intake control valve 6, and the low liquid level sensor 12 is communicatively connected with the exhaust control valve 7 and the liquid discharge control valve 9. Under normal liquid inflow, after the liquid level reaches the height sensed by the high liquid level sensor 11, the liquid inlet control valve 8 and the exhaust control valve 7 are closed, and the degassing tank 1 starts to degas; if the air pressure in the degassing tank 1 is too low after the exhaust control valve 7 is closed, causing the liquid level to continue to rise and appear higher than the height sensed by the high liquid level sensor 11, the air inlet control valve 6 is opened to transport a certain amount of sterile gas into the degassing tank 1; when the exhaust control valve 7 is closed, if the liquid level is lower than the height sensed by the low liquid level sensor 12, the exhaust control valve 7 is controlled to be opened, and the liquid discharge control valve 9 is closed, and the liquid inlet flow rate is increased at the same time to avoid the problem of air entering the discharge pipe 5 due to the low liquid level, and to form a safe disposal space between the low liquid level sensor 12 and the liquid inlet end of the discharge pipe 5, so as to provide sufficient operating time for restoring the liquid level to a normal position; generally speaking, the liquid level needs to be maintained at a state not higher than the height sensed by the high liquid level sensor 11 and not lower than the height sensed by the low liquid level sensor 12.

[0040] In some specific embodiments, the high liquid level sensor 11 and the low liquid level sensor 12 are respectively detachably connected to the main tank body 110. In this way, the high liquid level sensor 11 and the low liquid level sensor 12 can be more conveniently maintained and replaced, and detachable mounting positions of different heights can be set on the degassing tank 1 to meet different liquid level sensing requirements.

[0041] See also Figure 6 In order to realize the aforementioned detachable connection, the side wall of the degassing tank 1 is provided with a transparent window 101 (such as Figure 6 As shown in the dotted area in the figure, an upwardly opening mounting groove 13 is provided on the outside of the transparent window 101, and a cable receiving notch 1301 is provided on the side wall of the mounting groove 13. The high liquid level sensor 11 or the low liquid level sensor 12 is inserted into the mounting groove 13 from the top of the mounting groove 13 downward, and the sensing surface of the high liquid level sensor 11 or the low liquid level sensor 12 faces the transparent window 101 to facilitate sensing of the liquid level. The cable of the high liquid level sensor 11 or the low liquid level sensor 12 passes through the cable receiving notch to facilitate wiring. In this embodiment, the high liquid level sensor 11 and the low liquid level sensor 12 are photoelectric sensors, and existing sensors can be used, which will not be described here; correspondingly, the transparent window 101 can be made of glass or resin, which has high transparency and can meet the photoelectric sensing requirements.

[0042] In some embodiments, see Figures 1 to 5, the liquid inlet port of the drain pipe 5 is located at the bottom wall of the degassing tank 1. On the one hand, it can maximize the height of the safety space between the low liquid level sensor 12 and the liquid inlet end of the drain pipe 5, and extend the allowable operation time of liquid level adjustment as much as possible. On the other hand, it can also effectively drain the liquid when cleaning the degassing tank 1 to avoid liquid accumulation at the bottom of the degassing tank 1. More specifically, a guiding slope is provided at the bottom of the degassing tank 1, and the liquid inlet port of the drain pipe 5 is located at the lower end of the guiding slope.

[0043] In some embodiments, referring to Figures 1 to 5 , the liquid outlet end of the inlet pipe 4 is higher than the low liquid level sensor 12 and lower than the high liquid level sensor 11. During the initial liquid inlet, the liquid overflows from the upper end of the inlet pipe 4 and falls downward to the bottom of the degassing tank 1. During the process of hitting the bottom, some tiny bubbles can be broken, and then some gas can be released, which is beneficial to improving the degassing efficiency; when the liquid level gradually rises until it is higher than the upper port of the inlet pipe 4, due to the relatively high position of the liquid outlet end of the inlet pipe 4, the liquid outlet resistance is small, and the process of transporting the liquid into the degassing tank 1 is smoother.

[0044] In some embodiments, referring to Figures 1 to 5 , a pressure sensor 14 is provided in the degassing tank 1. The pressure sensor 14 is higher than the high liquid level sensor 11 to sense the air pressure above the liquid. Among them, the pressure sensor 14 is communicatively connected to the exhaust control valve 7 and the intake control valve 6. After the exhaust control valve 7 is closed, if it senses that the air pressure above the liquid is higher than the high pressure value, the exhaust control valve 7 is opened to relieve the pressure until the air pressure is lower than the high pressure value to avoid safety accidents caused by too high air pressure in the tank; after the exhaust control valve 7 is closed, if it senses that the air pressure above the liquid is lower than the low pressure value, the intake control valve 6 is controlled to transport sterile gas into the tank to maintain the air pressure balance in the tank, prevent the liquid level from rising continuously, and avoid safety accidents caused by too high liquid level in the tank.

[0045] In some embodiments, referring to Figure 7, To facilitate the installation of the pressure sensor 14 and provide good protection at the same time, the degassing system for vaccine production further includes a protective box 15, a first gasket 16, a second gasket 17, a pressure ring 18, and a sealing ring 19; a first through hole is provided on one side of the protective box 15 facing the main tank 110, and a second through hole is correspondingly provided on the side wall of the main tank 110. The protective box 15 is fixed to the outer side wall of the main tank 110 by welding or other means; the sensing part of the pressure sensor 14 sequentially penetrates through the first through hole and the second through hole, and the first gasket 16 is tightly sleeved on the outer periphery of the sensing part. The processing part of the pressure sensor 14 cooperates with the inner wall of the protective box 15 to clamp the first gasket 16; the second gasket 17 and the pressure ring 18 are sleeved on the outer periphery of the sensing part, and both are located between the protective box 15 and the main tank 110. The side wall of the main tank 110 directly contacts the rigid pressure ring 18, so that the pressure ring 18 can cooperate with the outer wall of the protective box 15 to clamp the second gasket 17. Effective sealing is achieved at the first through hole through the cooperation of the first gasket 16 and the second gasket 17 to prevent dirty substances from entering the protective box 15; the sealing ring 19 is provided on the outer periphery of the sensing part, and the outer peripheral surface of the sealing ring 19 is in close contact with the inner wall of the second through hole, and the inner peripheral surface is in close contact with the sensing part, so as to achieve effective sealing at the second through hole and prevent the liquid in the main tank 110 from overflowing.

[0046] On the basis of the above implementation, the protective box 15 includes a box body 1510 and a cover body 1520. An opening is provided on the side of the box body 1510 facing away from the main tank 110, and the cover body 1520 is detachably provided at the opening through a threaded connection structure. On the premise of ensuring the overall sealing of the protective box 15, when the pressure sensor 14 needs to be maintained, the cover body 1520 is removed, and the pressure sensor 14 is pulled outwards. After the maintenance is in place, the pressure sensor 14 is inserted again. More specifically, in order to collect the sensing data of the pressure sensor 14 and ensure the sealing performance at the same time, a wireless signal transceiver is fixed in the box body 1510. The wireless signal transceiver is electrically connected to the pressure sensor 14, and the sensing data of the pressure sensor 14 can be sent to the upper computer through the wireless signal transceiver.

[0047] In some embodiments, refer to Figures 1 to 5 , A filter 20 is connected to the outlet side of the exhaust control valve 7. When the exhaust control valve 7 is in the open state, the filter 20 can filter bacteria and other pollutants in the outside air to prevent them from entering the degassing tank 1 and ensure that the inside of the system is not contaminated.

[0048] On the basis of the above embodiment, refer to Figures 1 to 5 , An exhaust transition pipe 21 is connected between the exhaust control valve 7 and the filter 20 to facilitate the flexible setting of the spatial positions of the exhaust control valve 7 and the filter 20 and facilitate the connection and ventilation between the two.

[0049] In some embodiments, refer to Figures 1 to 5, the liquid inlet control valve 8 further has a first row of outlet ports, and a first exhaust pipe 223 for discharging steam is connected to the first row of outlet ports. During use, by adjusting the flow passage of the liquid inlet control valve 8, the pipe on the liquid outlet side of the liquid inlet control valve 8 is communicated with the first exhaust pipe 223, while the pipes on the liquid inlet side of the liquid inlet control valve 8 and the pipe on the liquid outlet side of the liquid inlet control valve 8 are both blocked, effectively discharging the steam and preventing the steam from accumulating in the liquid inlet control valve 8 and the pipes on the liquid inlet side of the liquid inlet control valve 8. More specifically, in order to better draw out the steam, a suction pump can be connected to the first exhaust pipe 223. The pipes on the liquid outlet side and the liquid inlet side of the liquid inlet control valve 8 together form the liquid inlet pipe 4.

[0050] In some embodiments, refer to Figures 1 to 5 , the liquid discharge control valve 9 further has a second row of outlet ports, and a second exhaust pipe 233 for discharging steam is connected to the second row of outlet ports. During use, by adjusting the flow passage of the liquid inlet control valve 8, the pipe on the liquid inlet side of the liquid discharge control valve 9 is communicated with the second exhaust pipe 233, while the pipes on the liquid outlet side of the liquid discharge control valve 9 and the pipe on the liquid inlet side of the liquid discharge control valve 9 are both blocked, effectively discharging the steam and preventing the steam from accumulating in the liquid discharge control valve 9 and the pipes on the liquid outlet side of the liquid discharge control valve 9. More specifically, in order to better draw out the steam, a suction pump can be connected to the second exhaust pipe 233. The pipes on the liquid outlet side and the liquid inlet side of the liquid discharge control valve 9 together form the liquid discharge pipe 5.

[0051] In some embodiments, refer to Figures 1 to 5 , the air inlet control valve 6 further has a main air inlet and a main air outlet. The main air inlet is connected with an air inlet transition pipe 24 for facilitating connection with a sterile air source, and the air inlet pipe 2 is connected between the main air outlet and the degassing tank 1.

[0052] In some embodiments, in order to achieve the degassing function, the degassing tank 1 includes a main tank body 110 and a degassing device 120. Among them, the implementation manners of the degassing device 120 include but are not limited to the following several types:

[0053] 1) The degassing device 120 includes a vacuum suction device and a vacuum suction pipe ( Figure 1 not shown in the figure) that are connected to each other. The vacuum suction pipe is connected to the upper part of the main tank body 110. During the degassing process, the vacuum suction device creates a negative pressure environment above the liquid through the vacuum suction pipe, and the tiny bubbles dissolved in the liquid are precipitated through the pressure difference to achieve degassing.

[0054] 2) Refer to Figure 2, the degassing device 120 includes a driver 121 and a disturbing blade 122. The driver 121 is disposed outside the main tank 110, and its drive shaft penetrates through the main tank 110. The disturbing blade 122 is disposed at the penetrating end of the drive shaft. Driven by the driver 121, the disturbing blade 122 rotates, generating disturbances in the liquid, enabling bubbles to rise and burst, and discharging them outside the liquid, thereby playing a role in degassing.

[0055] 3) Refer to Figure 3 , the degassing device 120 includes a heater 123 disposed on the outer periphery of the main tank 110, which appropriately heats the liquid in the main tank 110 by means of electric heating, enhancing the activity of the bubbles in the liquid, and then enabling the bubbles to rise and burst, discharging them outside the liquid, playing a role in degassing.

[0056] Specific implementation for implementation method 3): There are multiple heaters 123, and each heater 123 includes a housing and a resistance wire disposed inside the housing. The multiple housings are arranged around the main tank 110, and a resistance wire is disposed inside each housing. A magnetic attracting member is provided on the side of the housing facing the main tank 110. During installation, it is adsorbed on the main tank 110 through the magnetic attracting member, and then the installation is completed. After use, the heater 123 can be directly removed. In this way, the number of heaters 123 can be reasonably set according to actual usage requirements, and the use is more flexible.

[0057] 4) Refer to Figure 4 , the degassing device 120 includes an ultrasonic generator 124. The ultrasonic generator 124 is disposed inside the main tank 110, and the liquid generates high-frequency vibrations through ultrasonic waves, thereby causing the bubbles inside the liquid to burst and the gas to precipitate. Specifically, the ultrasonic generator 124 is connected to the side wall of the main tank 110. To improve the degassing efficiency, multiple ultrasonic generators 124 are evenly arranged along the circumferential direction of the main tank 110.

[0058] 5) Refer to Figure 5 , the degassing device 120 includes a helium inlet pipe 125 and an air outlet plate 126. The helium inlet pipe 125 penetrates through the main tank 110, and its air outlet end is connected to the air inlet end of the air outlet plate 126; the air outlet plate 126 is located at the bottom of the main tank 110, and a plurality of parallel air outlet channels are provided inside it. The air outlet end of each air outlet channel is respectively connected to different air outlet ports, and the air outlet ports are evenly distributed on the upper surface of the air outlet plate 126. This method utilizes the characteristic that the solubility of helium in the liquid is relatively low. By introducing it into the liquid at a pressure of 0.1 MPa and a flow rate of about 60 mL / min for 10 - 15 minutes, the dissolved air, especially oxygen, can be effectively removed. More specifically, a jet flow device is provided at the air outlet port, which can more effectively remove the gas from the liquid.

[0059] The above are only the preferred embodiments of the present utility model and are not intended to limit the present utility model. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principle of the present utility model shall be included within the protection scope of the present utility model.

Claims

1. A degassing system for vaccine production, characterized in that: include: A degassing tank (1), wherein the top of the degassing tank (1) is connected to an air inlet pipe (2) and an exhaust pipe (3), and the bottom of the degassing tank (1) is connected to a liquid inlet pipe (4) and a liquid discharge pipe (5); The air intake pipe (2) is provided with an air intake control valve (6), the exhaust pipe (3) is provided with an exhaust control valve (7), the liquid intake pipe (4) is provided with a liquid intake control valve (8), the liquid discharge pipe (5) is provided with a liquid discharge control valve (9), and the air intake control valve (6) also has a steam inlet, and the steam inlet is connected to a steam input pipe (10).

2. The degassing system for vaccine production according to claim 1, characterized in that: The degassing tank (1) is provided with a high liquid level sensor (11) and a low liquid level sensor (12) located below the high liquid level sensor (11), and the liquid inlet end of the liquid discharge pipe (5) is lower than the low liquid level sensor (12).

3. The degassing system for vaccine production according to claim 2, characterized in that: The liquid inlet port of the liquid discharge pipe (5) is located on the bottom wall of the degassing tank (1).

4. The degassing system for vaccine production according to claim 2, characterized in that: The liquid outlet end of the liquid inlet pipe (4) is higher than the low liquid level sensor (12) and lower than the high liquid level sensor (11).

5. The degassing system for vaccine production according to claim 2, characterized in that: An air pressure sensor (14) is provided in the degassing tank (1), and the air pressure sensor (14) is higher than the high liquid level sensor (11).

6. The degassing system for vaccine production according to claim 1, characterized in that: The gas outlet side of the exhaust control valve (7) is connected to a filter (20).

7. The degassing system for vaccine production according to claim 6, characterized in that: An exhaust transition pipe (21) is connected between the exhaust control valve (7) and the filter (20).

8. The degassing system for vaccine production according to claim 1, characterized in that: The liquid inlet control valve (8) also has a first discharge port, and the first discharge port is connected to a first exhaust pipe (22) (3) for exhausting steam.

9. The degassing system for vaccine production according to claim 1, characterized in that: The liquid discharge control valve (9) also has a second discharge port, and the second discharge port is connected to a second exhaust pipe (23) (3) for discharging steam.

10. The degassing system for vaccine production according to claim 1, characterized in that: The air intake control valve (6) also has a main air intake port and a main air outlet port, the main air intake port is connected to an air intake transition pipe (24), and the air intake pipe (2) is connected between the main air outlet port and the degassing tank (1).

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