Uniform shaking device for immune cells

Abstract

The utility model provides a uniform shaking device for immune cells, and relates to the technical field of shaking devices. The uniform shaking device for the immune cells comprises an operation table, supporting legs are arranged on the periphery of the lower end of the operation table, a rotating mechanism is arranged in the operation table, and clamping mechanisms are rotationally connected to the periphery of the upper end of the operation table. In this way, manpower and time are saved, it can be ensured that the culture containers are evenly stressed during shaking, multiple sets of culture containers are rotated at the same time, immune cells are evenly distributed, the shaking effect is remarkably improved, later medical research is facilitated, operation is easy, and use is convenient and fast; according to the uniform shaking device for the immune cells, the uniform mixing effect on the immune cells can be improved, and meanwhile, the phenomenon that a culture bottle moves due to vibration generated when related equipment such as a motor works can be effectively avoided.

Description

Technical Field

[0001] The utility model relates to a device for evenly shaking immune cells, specifically a device for evenly shaking immune cells, belonging to the technical field of shaking devices. Background Technique

[0002] Immune cells refer to cells that participate in or are related to immune responses. They include lymphocytes, dendritic cells, monocytes / macrophages, granulocytes, mast cells, etc. Immune cells can be divided into many types, and various immune cells play important roles in the human body. Immune cells are commonly known as white blood cells, including innate lymphocytes, various phagocytes, etc., and lymphocytes that can recognize antigens and produce specific immune responses. After pretreatment of peripheral blood, the amplification of immune cells is mostly carried out in immune cell culture flasks. The immune cell culture flasks are placed in an incubator with a certain temperature, humidity, and carbon dioxide content. After a period of culture, the immune cells in them are amplified.

[0003] The existing patent application number is CN218107489U. The utility model relates to a device for evenly shaking immune cells, including an installation box body; a plurality of support parts, which are all arranged on the lower surface of the installation box body; a vibration motor, which is arranged on the lower surface of the installation box body; a plurality of clamping parts, which are all arranged on the upper surface of the installation box body, and the clamping part includes a fixture installation box; a driving part, which is arranged inside the installation box body and is used to rotate the fixture installation box. Under the action of the support part and the vibration motor, it can improve the mixing effect of immune cells while effectively avoiding the phenomenon that the utility model moves due to the vibration generated by the vibration motor during operation.

[0004] Traditionally, it is generally static culture. Due to gravity, immune cells will settle to the bottom of the culture flask, resulting in uneven distribution of immune cells, which restricts the amplification of immune cells to a certain extent. Usually, in order to prevent uneven distribution of immune cells, the culture flask is shaken manually, which is time-consuming and laborious, and at the same time, it is easy to cause uneven force and poor shaking effect. Content of the Utility Model

[0005] (1) Technical Problems to be Solved

[0006] The purpose of the present utility model is to provide a device for evenly shaking immune cells to solve the above problems, that is, in the prior art, it is generally static culture. Due to gravity, immune cells will settle to the bottom of the culture flask, resulting in uneven distribution of immune cells, which restricts the amplification of immune cells to a certain extent. Usually, in order to prevent uneven distribution of immune cells, the culture flask is shaken manually, which is time-consuming and laborious, and at the same time, it is easy to cause uneven force and poor shaking effect.

[0007] (2) Technical Solutions

[0008] The present utility model is realized through the following technical solutions: a uniform shaking device for immune cells.

[0009] It includes an operating table, support feet are arranged around the lower end of the operating table, a rotating mechanism is arranged inside the operating table, and clamping mechanisms are rotatably connected around the upper end of the operating table.

[0010] Preferably, the rotating mechanism includes a motor, the upper end of the motor is detachably connected to the lower end of the operating table, a first rotating rod is arranged on the output shaft of the motor, a driving gear is arranged on the outer wall of the first rotating rod, a driven gear is meshed with the outer wall of the driving gear, and a second rotating rod is inserted in the middle of the driven gear.

[0011] Preferably, the output shaft of the motor is in transmission connection with the lower end of the first rotating rod, and the outer wall of the first rotating rod is fixedly connected to the inner wall of the driving gear through a key.

[0012] Preferably, the driven gear and the second rotating rod are evenly distributed around the outer side wall of the driving gear and the number is six.

[0013] Preferably, the clamping mechanism includes a placement table, the lower end of the placement table is fixedly connected to the upper end of the second rotating rod, an installation cavity is arranged inside the placement table, a rotating column is arranged in the middle of the installation cavity, a toothed ring is sleeved on the outer wall of the rotating column, an electric telescopic rod is bolted to one side of the placement table, a toothed plate is fixedly connected to the telescopic end of the electric telescopic rod, a chute is embedded in the inner wall of the placement table, a slider is slidably connected to the inner wall of the chute, a connecting rod is fixedly connected to the upper end of the slider, a clamping block is sleeved on the outer wall of the connecting rod, a circular plate is sleeved on the upper end outer wall of the rotating column, and a guiding groove is opened in the inner wall of the circular plate.

[0014] Preferably, the inner wall of the placement table is inlaid with the outer wall of the installation cavity, and the bottom wall of the inner cavity of the installation cavity is rotatably connected to the lower end of the rotating column.

[0015] Preferably, the upper end of the support foot is fixedly connected to the lower end of the operating table, and the upper end of the rotating mechanism is detachably connected to the lower end of the operating table.

[0016] The present utility model provides a uniform shaking device for immune cells, and the beneficial effects thereof are as follows:

[0017] 1. This uniform shaking device for immune cells can replace the traditional manual shaking method of culture containers. This not only saves manpower and time, but also ensures that the culture containers are shaken with uniform force. Multiple groups of culture containers can be rotated simultaneously, enabling the immune cells to be evenly distributed, significantly improving the shaking effect, and being beneficial for subsequent medical research. The operation is simple and the use is convenient.

[0018] 2. The uniform shaking device for immune cells can improve the mixing effect of immune cells while effectively avoiding the phenomenon that the culture flask moves due to the vibration generated by motors and other related equipment during operation. It can further enhance the mixing effect of immune cells, and at the same time, it can fix culture containers of different sizes containing immune cells and can also minimize the damage of the culture containers during the clamping process, improving the applicability of the device. Brief Description of the Drawings

[0019] Figure 1 It is a schematic diagram of the overall structure of the present utility model;

[0020] Figure 2 It is a schematic diagram of the structure of the rotating mechanism of the present utility model;

[0021] Figure 3 It is a schematic diagram of the structure of the clamping mechanism of the present utility model;

[0022] Figure 4 It is a schematic diagram of the structure of the details of the clamping mechanism of the present utility model;

[0023] Figure 5 It is a side view of the present utility model.

[0024]

Description of the Main Component Symbols

[0025] 1. Operating table; 2. Support feet; 3. Rotating mechanism; 4. Clamping mechanism; 31. Motor; 32. First rotating rod; 33. Driving gear; 34. Driven gear; 35. Second rotating rod; 41. Placing table; 42. Installation cavity; 43. Rotating column; 44. Tooth ring; 45. Electric telescopic rod; 46. Tooth plate; 47. Chute; 48. Slide block; 49. Connecting rod; 410. Clamping block; 411. Circular plate; 412. Guide groove. Detailed Embodiment

[0026] An embodiment of the present utility model provides a uniform shaking device for immune cells.

[0027] Please refer to Figure 1 , Figure 2 , Figure 3 , Figure 4 and Figure 5 , which includes an operating table 1. Support feet 2 are arranged around the lower end of the operating table 1. A rotating mechanism 3 is arranged inside the operating table 1. A clamping mechanism 4 is rotatably connected around the upper end of the operating table 1. The upper end of the support feet 2 is fixedly connected to the lower end of the operating table 1. The upper end of the rotating mechanism 3 is detachably connected to the lower end of the operating table 1.

[0028] Please refer to again Figure 2, the rotating mechanism 3 includes a motor 31. The upper end of the motor 31 is detachably connected to the lower end of the operating table 1. A first rotating rod 32 is provided on the output shaft of the motor 31. A driving gear 33 is provided on the outer wall of the first rotating rod 32. A driven gear 34 is meshed with the outer wall of the driving gear 33. A second rotating rod 35 is inserted in the middle of the driven gear 34. The output shaft of the motor 31 is drivingly connected to the lower end of the first rotating rod 32. The outer wall of the first rotating rod 32 and the inner wall of the driving gear 33 are fixedly connected by a key. The driven gear 34 and the second rotating rod 35 are evenly distributed around the outer side wall of the driving gear 33 and the number is six.

[0029] When the utility model is in use: First, the operating table 1 is in the shape of a rectangular body or a cylinder, and a driving gear 33 is arranged at the center inside the operating table 1. A plurality of driven gears 34 are connected to the inner wall of the operating table 1. The driving gear 33 is meshed with the plurality of driven gears 34. Further, four supporting feet 2 are fixedly connected to the periphery of the lower end of the operating table 1, which can improve the stability of the device. Six second rotating rods 35 are arranged on the bottom wall of the inner cavity of the operating table 1. The upper ends of the second rotating rods 35 extend out of the upper end surface of the operating table 1, and driven gears 34 are fixedly installed at the centers of the outer walls of the second rotating rods 35, which is convenient for driving the second rotating rods 35 to rotate.

[0030] When it is necessary to shake the immune cells in the culture container, the staff places the culture container on the upper end surface of the circular plate 411, and then controls to start the motor 31. The motor 31 drives the first rotating rod 32 to rotate. While the first rotating rod 32 rotates, it drives the driving gear 33 to rotate, so that the driving gear 33 drives a plurality of driven gears 34 and the second rotating rods 35 to rotate, realizing the function of rotating and uniformly mixing the cells in the culture container.

[0031] Please refer to Figure Figure 3 and Figure 4 , the clamping mechanism 4 includes a placing table 41. The lower end of the placing table 41 is fixedly connected to the upper end of the second rotating rod 35. An installation cavity 42 is arranged inside the placing table 41. A rotating column 43 is arranged in the middle of the installation cavity 42. A toothed ring 44 is sleeved on the outer wall of the rotating column 43. An electric telescopic rod 45 is bolted to one side of the placing table 41. A toothed plate 46 is fixedly connected to the telescopic end of the electric telescopic rod 45. A sliding groove 47 is embedded in the inner wall of the placing table 41. A slider 48 is slidably connected to the inner wall of the sliding groove 47. A connecting rod 49 is fixedly connected to the upper end of the slider 48. A clamping block 410 is sleeved on the outer wall of the connecting rod 49. A circular plate 411 is sleeved on the upper end outer wall of the rotating column 43. A guiding groove 412 is opened on the inner wall of the circular plate 411. The inner wall of the placing table 41 is inlaid with the outer wall of the installation cavity 42. The bottom wall of the inner cavity of the installation cavity 42 is rotatably connected to the lower end of the rotating column 43.

[0032] When the utility model is in use: when it is necessary to fix the container containing immune cells, place the container in the middle of the upper end face of the circular plate 411, and then control the start of the electric telescopic rod 45. The output end of the electric telescopic rod 45 can drive the toothed plate 46 and the toothed ring 44 to move, so that the toothed plate 46 can drive the rotating column 43 to rotate. The circular plate 411 also rotates stably with the rotation of the rotating column 43. The circular plate 411 applies the acting force to the four connecting rods 49 simultaneously through the four guiding grooves 412 respectively, so that the four connecting rods 49 can continue to drive the four clamping blocks 410 and the sliders 48 to move along the track of the sliding groove 47. Further, the four clamping blocks 410 can fix the container.

[0033] The toothed plate 46 can move along the track of the electric telescopic rod 45, so that the toothed plate 46 can be conveniently engaged and disengaged with the toothed ring 44. It can not only adjust the distance between the four clamping blocks 410 relatively quickly. When the toothed plate 46 is engaged with the toothed ring 44, only by starting the electric telescopic rod 45 can the four clamping blocks 410 fix the container relatively stably, greatly improving the shaking efficiency of the container and reducing the labor intensity of the staff. By setting the toothed ring 44 to drive the rotating column 43 and the circular plate 411 to rotate, the circular plate 411 can conveniently and effectively apply the acting force to the four connecting rods 49 through the four guiding grooves 412 at the same time, which not only ensures that the movement strokes of the four clamping blocks 410 are consistent, but also effectively improves the convenience of the movement of the four connecting rods 49 and the clamping blocks 410, thus greatly improving the convenience of fixing the container and also greatly improving the accuracy of fixing the container.

[0034] The above shows and describes the basic principles, main features and advantages of the utility model. Those skilled in the art should understand that the utility model is not limited by the above embodiments. The above embodiments and the descriptions in the specification only illustrate the principles of the utility model. Without departing from the spirit and scope of the utility model, the utility model will have various changes and improvements, and these changes and improvements all fall within the scope of the utility model claimed. The scope of protection claimed by the utility model is defined by the appended claims and their equivalents.

Claims

1. A uniform shaking device for immune cells, comprising an operating table (1), characterized in that: The lower end of the operating table (1) is provided with supporting legs (2) around it, a rotating mechanism (3) is provided inside the operating table (1), and the upper end of the operating table (1) is rotatably connected with a clamping mechanism (4) around it; The rotating mechanism (3) comprises a motor (31), the upper end of the motor (31) is detachably connected to the lower end of the operating table (1), the output shaft of the motor (31) is provided with a rotating rod (32), the outer wall of the rotating rod (32) is provided with a driving gear (33), the outer wall of the driving gear (33) is meshingly connected with a driven gear (34), and the middle part of the driven gear (34) is plugged with a rotating rod (35); The clamping mechanism (4) comprises a placing platform (41), the lower end of the placing platform (41) is fixedly connected to the upper end of the second rotating rod (35), the interior of the placing platform (41) is provided with a mounting cavity (42), the middle part of the mounting cavity (42) is provided with a rotating column (43), the outer wall of the rotating column (43) is sleeved with a gear ring (44), one side of the placing platform (41) is bolted with an electric telescopic rod (45), and the telescopic movement of the electric telescopic rod (45) is controlled by the electric telescopic rod (45). The end is fixedly connected with a tooth plate (46), the inner wall of the placing platform (41) is embedded with a slide groove (47), the inner wall of the slide groove (47) is slidably connected with a slider (48), the upper end of the slider (48) is fixedly connected with a connecting rod (49), the outer wall of the connecting rod (49) is sleeved with a clamping block (410), the upper end outer wall of the rotating column (43) is sleeved with a circular plate (411), and the inner wall of the circular plate (411) is provided with a guide groove (412).

2. The uniform shaking device for immune cells according to claim 1, characterized in that: The output shaft of the motor (31) is transmission-connected to the lower end of the rotating rod (32), and the outer wall of the rotating rod (32) is fixedly connected to the inner wall of the driving gear (33) via a key.

3. The uniform shaking device for immune cells according to claim 1, characterized in that: The driven gear (34) and the second rotating rod (35) are evenly distributed around the outer wall of the driving gear (33) and there are six of them.

4. The uniform shaking device for immune cells according to claim 1, characterized in that: The inner wall of the placement platform (41) is inlaid and connected with the outer wall of the installation cavity (42), and the inner cavity bottom wall of the installation cavity (42) is rotatably connected with the lower end of the rotating column (43).

5. The uniform shaking device for immune cells according to claim 1, characterized in that: The upper end of the support foot (2) is fixedly connected to the lower end of the operating table (1), and the upper end of the rotating mechanism (3) is detachably connected to the lower end of the operating table (1).

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