Treatment plate for magnetic solid phase extraction

By setting synapses at the bottom of the treatment hole, forming a pore-like structure from large to small and then to large, the problems of low magnetic absorption sensitivity and slow blow drying rate in the prior art are solved, and the reagent dosage and the treatment efficiency are improved.

CN223055133UActive Publication Date: 2025-07-04SHANGHAI RIDGE TECHNOLOGY CO LTD
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Patent Information

Application Number
CN202422134210.1
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-08-30
Publication Date
2025-07-04
Estimated Expiration
2034-08-30

AI Technical Summary

Technical Problem

The bottom diameter of the existing magnetic solid-phase extraction treatment plate is large, resulting in low magnetic absorption sensitivity and large reagent during elution; the pressure is small during nitrogen blowing, which reduces the blow drying rate.

Method used

Synapses are arranged at the bottom of the treatment hole to form a pore-like structure from large to small and then to large, enhancing pressure, reducing reagent volume, and improving magnetic absorption sensitivity and blow-drying rate.

Benefits of technology

Through synaptic design, the amount of reagent is reduced, the magnetic absorption sensitivity and blow drying rate are improved, and the processing efficiency is enhanced.

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Abstract

The utility model provides a processing plate for magnetic solid phase extraction, which relates to the field of magnetic solid phase extraction and comprises an upper outer frame, processing holes, synapses and a lower outer frame, a plurality of processing holes are distributed on the upper outer frame in an array mode, the bottoms of the processing holes are connected with the synapses corresponding to the processing holes, the synapses are connected to the lower outer frame, and the upper outer frame is connected with the lower outer frame in a matched mode. The synapses are arranged at the bottom of the retreatment hole, so that the internal space is occupied, the volume in the hole is reduced, the volume of a reagent is reduced, and the magnetic attraction sensitivity is improved; the multiple synapses form a porous structure with the diameter from large to small and then from large at the bottom, the pressure intensity is increased, the nitrogen flow rate can be increased, the blow-drying rate is increased, the time is shortened, and degradation of compounds is reduced.
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Description

Technical Field

[0001] The utility model relates to the field of magnetic solid-phase extraction, and specifically, to a processing plate for magnetic solid-phase extraction. Background Art

[0002] Solid-phase extraction is a hot spot in the development of analytical sample pretreatment technology, and can be used for the separation, purification and enrichment of analytes in samples. Solid-phase extraction can be used for the treatment of gas, liquid and solid samples, and is widely used in the fields of medical treatment, food safety, environmental detection, commodity inspection, chemical industry quality control, etc. In recent years, microextraction methods have developed rapidly. Compared with traditional large-scale extraction methods, microextraction has higher recovery rate, more effective separation, faster speed, less consumption of extraction phase, higher selectivity, simpler pretreatment process and more convenient operation. And it has the possibility of automation and being combined with detection means such as chromatography and electrophoresis.

[0003] Currently, for the existing processing plates for magnetic solid-phase extraction, the bottom is not specially treated, the bottom diameter is large, and a relatively large amount of liquid reagent is required during elution, resulting in a decrease in magnetic absorption sensitivity. At the same time, during the nitrogen blowing process, for the processing holes with a through design, the pressure is relatively small, reducing the drying rate. Summary of the Utility Model

[0004] Aiming at the defects in the prior art, the purpose of the utility model is to provide a processing plate for magnetic solid-phase extraction.

[0005] According to the processing plate for magnetic solid-phase extraction provided by the utility model, it includes: an upper outer frame, processing holes, synapses and a lower outer frame. A plurality of processing holes are arrayed and distributed on the upper outer frame. The bottom of the processing hole is connected with a corresponding synapse, and the synapse is connected to the lower outer frame. The upper outer frame and the lower outer frame are adaptively connected.

[0006] Preferably, the bottom of the processing hole forms a hole-shaped structure with a diameter that becomes larger, then smaller, and then larger through the synapse.

[0007] Preferably, a plurality of synapses are distributed around the bottom of the processing hole.

[0008] Preferably, the synapse is in a semi-arc shape.

[0009] Preferably, the height of the synapse is 3 - 5 mm.

[0010] Preferably, the thickness of the synapse is less than or equal to 4 mm.

[0011] Preferably, the synapse is integrally connected to the upper outer frame and the lower outer frame respectively.

[0012] Preferably, the processing hole is a through hole, and the inner diameter of the processing hole is greater than 5 mm.

[0013] Preferably, there are numerical markings on the horizontal axis of the upper outer frame and letter markings on the vertical axis of the upper outer frame.

[0014] Preferably, the number of processing holes is 96.

[0015] Compared with the prior art, the utility model has the following beneficial effects:

[0016] In this application, synapses are arranged at the bottom of the reprocessing holes, occupying the internal space, resulting in a reduction in the volume inside the holes, thereby reducing the volume of the reagent and enhancing the magnetic absorption sensitivity; multiple synapses form a hole-like structure with a diameter that first decreases, then increases, and then decreases again at the bottom, increasing the pressure, which can increase the nitrogen gas flow rate, improve the drying rate, reduce the time, and reduce the degradation of compounds. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] By reading the following detailed description of the non-restrictive embodiments with reference to the accompanying drawings, other features, objectives, and advantages of the utility model will become more apparent:

[0018] Figure 1 It is a schematic diagram of the overall structure of the utility model.

[0019] The figure shows: upper outer frame 1, processing hole 2, synapse 3, lower outer frame 4. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0020] The following will describe the utility model in detail with reference to specific embodiments. The following embodiments will help those skilled in the art to further understand the utility model, but do not limit the utility model in any form. It should be noted that for those of ordinary skill in the art, without departing from the concept of the utility model, several changes and improvements can still be made. These all fall within the protection scope of the utility model.

[0021] Embodiment

[0022] According to a processing plate for magnetic solid-phase extraction provided by the utility model, as Figure 1 shown, it includes: an upper outer frame 1, processing holes 2, synapses 3, and a lower outer frame 4. There are 96 processing holes 2 arranged in an array on the upper outer frame 1. The processing holes 2 are through holes, and the inner diameter of the processing holes 2 is greater than 5 mm, which can accommodate a 5-mm magnetic rod sleeve to pass through. The bottom of the processing hole 2 is connected to a corresponding synapse 3, and the synapse 3 is connected to the lower outer frame 4. Through the design of the synapse 3, the diameter of the bottom is reduced, which can reduce the volume of the elution reagent, thereby increasing the concentration multiple and improving the extraction rate. The upper outer frame 1 and the lower outer frame 4 are adaptively connected to improve stability. Moreover, Arabic numerals (1-12) are marked on the horizontal axis of the upper outer frame 1, and English letters (A-H) are marked on the vertical axis, which serves to clarify the rows and columns. This processing plate has 96 processing holes for adding reagents or samples and can process 96 samples simultaneously.

[0023] The synapse 3 is integrally connected to the upper outer frame 1 and the lower outer frame 4 respectively; the height of the synapse 3 is 4 mm, the thickness of the synapse 3 is less than or equal to 4 mm, and the thickness at the last part is 4 mm. A plurality of synapses 3 are distributed around the bottom (the front, back, left, and right four faces) of the processing hole 2. The synapse 3 is in a semi-arc shape. The bottom of the processing hole 2 forms a hole-like structure with a diameter that first becomes larger, then smaller, and then larger through the synapse 3. During the nitrogen blowing process, the air flow passes through a structure similar to a small hole, which can increase the pressure and accelerate the rate of nitrogen drying.

[0024] More specifically, due to the presence of the synapse 3, the internal space is occupied, resulting in a reduction in the volume inside the hole. Therefore, when adding the same volume of reagent, due to the presence of the synapse 3, the liquid level rises, so the depth at which the magnetic rod probes below the liquid level increases.

[0025] In the description of the present application, it should be understood that the orientation or positional relationship indicated by the terms "upper", "lower", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", etc. is based on the orientation or positional relationship shown in the drawings. It is only for the convenience of describing the present application and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation. Therefore, it should not be construed as a limitation to the present application.

[0026] The specific embodiments of the present utility model have been described above. It should be understood that the present utility model is not limited to the above specific embodiments. Those skilled in the art can make various changes or modifications within the scope of the claims, which does not affect the essence of the present utility model. Without conflict, the embodiments of the present application and the features in the embodiments can be arbitrarily combined with each other.

Claims

1. A processing plate for magnetic solid-phase extraction, characterized in that, Comprising: An upper outer frame (1), processing holes (2), synapses (3) and a lower outer frame (4). A plurality of the processing holes (2) are arrayed and distributed on the upper outer frame (1). The bottom of each processing hole (2) is connected to a corresponding synapse (3). The synapses (3) are connected to the lower outer frame (4). The upper outer frame (1) and the lower outer frame (4) are adaptively connected.

2. The processing plate for magnetic solid phase extraction according to claim 1, wherein, The bottom of the processing hole (2) forms a hole-shaped structure with a diameter that first becomes smaller, then larger, and then smaller again through the synapse (3).

3. The processing plate for magnetic solid-phase extraction according to claim 1, wherein A plurality of the synapses (3) are distributed around the bottom of the processing hole (2).

4. The treatment plate for magnetic solid-phase extraction according to claim 1, characterized in that, The synapse (3) is in a semi-circular arc shape.

5. The processing plate for magnetic solid phase extraction according to claim 1, characterized in that, The height of the synapse (3) is 3 - 5 mm.

6. The processing plate for magnetic solid-phase extraction according to claim 1, characterized in that, The thickness of the synapse (3) is less than or equal to 4 mm.

7. The treatment plate for magnetic solid-phase extraction according to claim 1, wherein The synapses (3) are integrally connected to the upper outer frame (1) and the lower outer frame (4) respectively.

8. The processing plate for magnetic solid phase extraction according to claim 1, wherein, The processing hole (2) is a through hole, and the inner diameter of the processing hole (2) is greater than 5 mm.

9. The treatment plate for magnetic solid-phase extraction according to claim 1, characterized in that, Digital markings are provided on the horizontal axis of the upper outer frame (1), and letter markings are provided on the vertical axis of the upper outer frame (1).

10. The processing plate for magnetic solid-phase extraction according to claim 1, characterized in that, The number of the processing holes (2) is 96.