Allergen specificity IgE (Immunoglobulin E) detection plate

By designing an allergen-specific IgE detection plate and using natural precipitation to separate serum and red blood cells, the problem of inaccurate detection results is solved and the accuracy and safety of the detection is ensured.

CN223091972UActive Publication Date: 2025-07-11SHENZHEN BIOCUP BIOTECH CO LTD
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Patent Information

Application Number
CN202421447360.1
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-06-24
Publication Date
2025-07-11
Estimated Expiration
2034-06-24

AI Technical Summary

Technical Problem

The existing allergen-specific IgE detection structure fails to effectively separate serum and red blood cells, resulting in inaccurate detection results, and the lack of protective structures leads to foreign matter falling into affecting the detection results.

Method used

An allergen-specific IgE detection plate is designed, including a base plate, a cover plate, a sealing membrane and a protective component to separate serum and red blood cells through natural precipitation, and ensure the stability and safety of the detection process through protective components.

Benefits of technology

The natural separation of serum and red blood cells is achieved, the accuracy of detection is improved, and the safety and stability of the detection process is ensured through protective components.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses an allergen specificity IgE (Immunoglobulin E) detection plate, which belongs to the technical field of allergen detection cards and comprises a bottom plate, a cover plate is hinged on the bottom plate, a large notch and a small notch which are correspondingly distributed at equal intervals are respectively connected on the bottom plate, and the large notch and the small notch are connected through an inclined opening with a downward opening; the sealing film is adhesively fixed to the edge, close to the outer wall of the inclined opening, of the large notch, and a lifting lug matched with the sealing film is connected to the sealing film; and the protection assembly comprises a clamping block which is arranged on the cover plate and integrally formed, the clamping block is connected with a bayonet in the bottom plate in a limiting mode, the protection assembly further comprises a rotating ring movably connected to the bottom plate, and the rotating ring is connected with a reciprocating lead screw through a movable shaft and extends to the reciprocating lead screw. According to the utility model, whole blood sampling can be directly carried out, the pretreatment step of a sample is effectively avoided, an allergic reagent reaction is directly carried out, and the accuracy of a detection result is improved.
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Description

Technical Field

[0001] The utility model belongs to the technical field of allergen detection cards, and specifically relates to an allergen-specific IgE detection plate. Background Art

[0002] Allergen-specific IgE generally refers to an allergen-specific IgE antibody present in human serum, which can mediate the occurrence of allergic reactions. Detecting allergen-specific IgE can help determine whether a patient has an allergic reaction to certain allergens. In case of abnormal allergen-specific IgE, contact with related allergenic substances should be avoided.

[0003] For general allergen blood tests, serum and red blood cells need to be separated first, and then serum and allergen sample reagents are added to detect the final result. However, existing detection structures do not separate serum from red blood cells and directly perform reactions with allergen reagents. Although this reduces operating costs, it affects the accuracy of the final detection. In addition, there is no protective structure on the detection card, resulting in inaccurate detection results when foreign objects accidentally fall into the sample addition hole. Content of the Utility Model

[0004] The purpose of the utility model is to provide an allergen-specific IgE detection plate to solve the technical problem that existing detection structures do not separate serum from red blood cells and directly perform reactions with allergen reagents, thus affecting the accuracy of the final detection.

[0005] To achieve the above purpose, the utility model adopts the following technical solutions:

[0006] An allergen-specific IgE detection plate, comprising:

[0007] A bottom plate, on which a cover plate is hingedly installed, and the bottom plate is respectively connected with equidistantly corresponding large notches and small notches, and the large notches and small notches are connected by an inclined notch with an opening downward;

[0008] A sealing film, on the outer wall edge of the large notch near the inclined notch, a sealing film is adhesively fixed, and a lifting ear adapted to it is connected to the sealing film;

[0009] A protection component, the protection component includes a block integrally formed on the cover plate, and the block is connected with a bayonet on the bottom plate in a limiting manner.

[0010] Further, the protection component further includes a rotating ring movably connected to the bottom plate, one end of the rotating ring is connected to a reciprocating lead screw extending into the bottom plate through a movable shaft, and both ends of the reciprocating lead screw are helically driven with blocks symmetrically centered on the block.

[0011] Further, one end of the stopper extends to the bayonet, and a strip groove is connected along the width direction of the bottom plate. As the rotating ring rotates, the stopper and the block on the cover plate are clamped or separated from each other.

[0012] Further, a rotating cavity is provided on the outer wall of the reciprocating lead screw and is placed inside the bottom plate.

[0013] Further, a socket for inserting and connecting with an external sampling straw is opened on the bottom plate.

[0014] In summary, due to the adoption of the above technical solutions, the beneficial effects of the present utility model are as follows:

[0015] (1) A sealing film connected by a large notch is provided. Through natural precipitation, serum and red blood cells will naturally separate. For the coagulated serum, the sealing film is torn off by lifting the ear. In this way, due to the action of gravity, the serum slides into the small notch through the inclined opening, thereby obtaining the serum, avoiding the influence of red blood cells on the detection of allergen characteristics, and improving the accuracy of detection data.

[0016] (2) A protection component is provided. When the detection board is not in use, the block on the cover plate is connected to the bayonet on the bottom plate in a limiting manner, and then the rotating ring is pushed to rotate to make the reciprocating lead screw move. With the help of the action of screw drive, the stopper further clamps and limits both ends of the block, ensuring the stability of the connection of the connecting piece, and thus improving the safety of the structure when not in use. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] In order to more clearly illustrate the technical solutions in the embodiments of the present utility model or the prior art, the following will briefly introduce the drawings required for use in the description of the embodiments or the prior art. Obviously, the drawings in the following description are only some embodiments of the present utility model. For those of ordinary skill in the art, other drawings can be obtained based on these drawings without creative efforts.

[0018] Figure 1 It is a schematic structural diagram of the allergen-specific IgE detection board of the present utility model Figure 1 ;

[0019] Figure 2 It is a schematic structural diagram of the allergen-specific IgE detection board of the present utility model Figure 2 ;

[0020] Figure 3 It is a schematic cross-sectional view of the front view direction of the bottom plate of the present utility model;

[0021] Figure 4 It is a schematic connection diagram of the reciprocating lead screw of the present utility model.

[0022] Reference numerals: 1, bottom plate; 2, cover plate; 3, large notch; 4, small notch; 5, inclined notch; 6, sealing film; 7, lifting ear; 8, protection component; 9, clamping block; 10, bayonet; 11, rotating ring; 12, reciprocating lead screw; 13, stop block; 14, strip groove; 15, socket. Detailed implementation manners

[0023] Next, the technical solutions in the embodiments of the present utility model will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present utility model. Obviously, the described embodiments are only a part of the embodiments of the present utility model, rather than all the embodiments. Based on the embodiments in the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present utility model.

[0024] Refer to the attached drawings of the specification Figures 1 - 4 As shown, an allergen-specific IgE detection plate includes:

[0025] A bottom plate 1, on which a cover plate 2 is hingedly installed, and the bottom plate 1 is respectively connected with large notches 3 and small notches 4 that are equally spaced and correspondingly distributed, and the large notch 3 and the small notch 4 are connected by an inclined notch 5 with an opening downward; a sealing film 6, on the large notch 3, a sealing film 6 is adhesively fixed near the outer wall edge of the inclined notch 5, and a lifting ear 7 adapted thereto is connected to the sealing film 6; a protection component 8, the protection component 8 includes a clamping block 9 integrally formed on the cover plate 2, and the clamping block 9 is in limit connection with a bayonet 10 on the bottom plate 1.

[0026] The protection component 8 further includes a rotating ring 11 movably connected to the bottom plate 1, the rotating ring 11 is fixedly connected to a reciprocating lead screw 12 extending into the interior of the bottom plate 1 through a movable shaft, both ends of the reciprocating lead screw 12 are helically driven with stop blocks 13 symmetrically centered on the clamping block 9, one end of the stop block 13 extends to the bayonet 10, and a strip groove 14 is connected to the stop block 13 along the width direction of the bottom plate 1. As the rotating ring 11 rotates, the stop block 13 and the clamping block 9 on the cover plate 2 are clamped or separated from each other, and a rotating cavity is provided on the outer wall of the reciprocating lead screw 12 and placed inside the bottom plate 1.

[0027] Specifically, the technical solution of this patent separates serum by the method of natural precipitation. The extracted venous blood is placed in the large notch 3 and left at room temperature to coagulate naturally and separate the serum. Generally, after a period of time, the serum and red blood cells will naturally separate, so as to obtain serum and improve the accuracy of the detection results. In addition, the shape setting of the large notch 3 can expand the cooling area, thereby reducing the natural cooling time and facilitating the detection work.

[0028] An insertion port 15 for connecting with an external sampling straw is provided on the bottom plate 1. The insertion port 15 on the bottom plate 1 is configured to provide a corresponding storage space for the sampling straw, thus facilitating the operation of medical staff. In addition, the protection component 8 can further provide a corresponding clamping effect for the cover plate 2 to be closed on the bottom plate 1, preventing the disconnection between the connecting parts and enhancing the protection performance of the device.

[0029] The above are only the preferred specific embodiments of the present invention, but the protection scope of the present invention is not limited thereto. Any person skilled in the art within the technical scope disclosed by the present invention, according to the technical solution of the present invention and its inventive concept, makes equivalent substitutions or changes, should be covered within the protection scope of the present invention.

[0030] The preferred embodiments of the present invention disclosed above are only used to help explain the present invention. The preferred embodiments do not describe all the details in detail, nor do they limit the present invention to only the specific embodiments. Obviously, many modifications and changes can be made according to the content of this specification. This specification selects and specifically describes these embodiments to better explain the principle and practical application of the present invention, so that those skilled in the art can well understand and utilize the present invention. The present invention is only limited by the claims and their full scope and equivalents.

Claims

1. An allergen-specific IgE detection panel, characterized in that, Including: A bottom plate (1), on which a cover plate (2) is hingedly installed, and equidistantly corresponding large notches (3) and small notches (4) are respectively connected to the bottom plate (1), and the large notches (3) and the small notches (4) are connected by an inclined notch (5) with an opening downward; A sealing film (6), the sealing film (6) is adhesively fixed on the outer wall edge of the large notch (3) near the inclined notch (5), and a lifting ear (7) adapted to it is connected to the sealing film (6); A protection component (8), the protection component (8) includes a clamping block (9) integrally formed on the cover plate (2), and the clamping block (9) is connected to a clamping notch (10) on the bottom plate (1) in a limiting manner.

2. The allergen-specific IgE test strip according to claim 1, characterized in that The protection component (8) further includes a rotating ring (11) movably connected to the bottom plate (1), the rotating ring (11) is connected to a reciprocating lead screw (12) extending into the interior of the bottom plate (1) through a movable shaft, and both ends of the reciprocating lead screw (12) are helically driven with a stop block (13) symmetrically centered on the clamping block (9).

3. The allergen-specific IgE test strip according to claim 2, wherein One end of the stop block (13) extends to the clamping notch (10), and a strip-shaped groove (14) is connected to the stop block (13) along the width direction of the bottom plate (1). As the rotating ring (11) rotates, the stop block (13) and the clamping block (9) on the cover plate (2) are clamped or separated from each other.

4. An allergen-specific IgE detection panel according to claim 2, characterized in that, A rotating cavity is provided on the outer wall of the reciprocating lead screw (12) and is located inside the bottom plate (1).

5. The allergen-specific IgE test strip according to claim 1, characterized in that, A socket (15) for inserting and connecting an external sampling straw is provided on the bottom plate (1).