In-vitro diagnostic reagent split charging device

Abstract

The utility model relates to an in-vitro diagnostic reagent split charging device which comprises a base, an installation plate is installed on the base, a servo motor, a lead screw and a guide mechanism are installed on the installation plate, trays are installed on the lead screw and the guide mechanism, and a motor shaft of the servo motor is connected with one end of the lead screw through a coupler. A door-shaped frame is further installed on the base, a reagent groove and eight metering pumps are installed at the top end of the door-shaped frame, a liquid injection nozzle installation frame is installed on the side, close to the servo motor, of the door-shaped frame, eight liquid injection nozzle installation blocks are installed on the liquid injection nozzle installation frame, and a liquid injection nozzle is installed in each liquid injection nozzle installation block. The top of the liquid injection nozzle is communicated with an outlet of the metering pump through a first hose, and an inlet of the metering pump is communicated with the reagent groove through a second hose. The heights of the liquid injection nozzles are indirectly adjusted by adjusting the heights of the liquid injection nozzle mounting frames, the distance between the liquid injection nozzles is indirectly adjusted by adjusting the distance between the liquid injection nozzle mounting blocks, and in-vitro diagnostic reagent split charging can be carried out on in-vitro diagnostic reagent split charging pipes of different specifications.

Description

Technical Field

[0001] The utility model relates to the technical field of reagent dispensing, in particular to an in vitro diagnostic reagent dispensing device. Background Art

[0002] In recent years, with the rapid development of biotechnology, more and more physiological indicators and disease diagnoses can be completed through in vitro diagnostic reagents. Therefore, the types of in vitro diagnostic reagents are increasing, and the specifications of in vitro diagnostic reagent dispensing tubes are also different. There are mainly two existing dispensing devices. One is to dispense each in vitro diagnostic reagent dispensing tube one by one. This kind of dispensing equipment has a high degree of automation and is suitable for large-scale dispensing. However, the single-batch dispensing volume of general in vitro diagnostic reagents is limited and not suitable for use. The other is to simultaneously dispense multiple in vitro diagnostic reagent dispensing tubes inserted in a tube rack, which is suitable for the dispensing of most in vitro diagnostic reagents with a small single-batch dispensing quantity.

[0003] In the utility model patent with the application number 202220768940.5, a new type of biological reagent dispensing device is disclosed. It includes a fixing plate and a plurality of hoses. A needle limiting block is bolted to one side of the fixing plate. One end of the hose is threadedly connected with a needle. A plurality of openings are formed between the needle limiting block and the fixing plate. The needle passes through the openings. A support seat and a hose passage are bolted to the other side of the fixing plate. A plurality of hose limiting grooves are arranged on the upper end surface of the support seat. The hoses respectively pass through the hose limiting grooves and the hose passage. Although it can simultaneously dispense multiple in vitro diagnostic reagent dispensing tubes inserted in a tube rack and can separately replace the needles that fail, the distance between the needles cannot be adjusted according to the spacing of in vitro diagnostic reagent dispensing tubes of different specifications, and the height of the needles cannot be adjusted. Summary of the Utility Model

[0004] The purpose of the utility model is to overcome the above problems existing in the prior art and provide an in vitro diagnostic reagent dispensing device.

[0005] To achieve the above technical purpose and reach the above technical effect, the utility model is realized through the following technical solutions:

[0006] An in vitro diagnostic reagent dispensing device includes a rectangular base. An installation plate capable of adjusting its position along the short side direction of the base is installed on the base. A servo motor, a lead screw, and a guiding mechanism are installed on the installation plate. A tray for placing in vitro diagnostic reagent dispensing tubes is installed on the lead screw and the guiding mechanism. The motor shaft of the servo motor is connected to one end of the lead screw through a coupling. A portal frame is also installed on the base. A reagent tank for loading reagents and eight metering pumps are installed at the top of the portal frame. A liquid injection nozzle mounting frame capable of adjusting its height is installed on one side of the portal frame close to the servo motor. Eight liquid injection nozzle mounting blocks capable of adjusting their positions along the short side direction of the base are installed on the liquid injection nozzle mounting frame. A vertically downward liquid injection nozzle is installed in each liquid injection nozzle mounting block. The top of the liquid injection nozzle is connected to the outlet of the metering pump through a first hose. The inlet of the metering pump is connected to the reagent tank through a second hose.

[0007] Among them, N first strip-shaped holes parallel to the short side of the base are opened on the installation plate. N locking bolts are screwed on the base. One locking bolt is inserted into each first strip-shaped hole.

[0008] Among them, the lead screw includes a screw rod and a lead screw nut that are screwed together. Both ends of the screw rod are respectively installed on the installation plate through a set of pedestal bearings. The lead screw nut is installed at the bottom end of the tray with screws.

[0009] Among them, the guiding mechanism includes a guiding rod and a guiding block. The guiding block is sleeved on the guiding rod. Both ends of the guiding rod are respectively installed on the installation plate through a set of pedestal bearings. The guiding block is installed at the bottom end of the tray with screws.

[0010] Among them, a circle of upwardly protruding limiting flanges is arranged around the tray.

[0011] Among them, the liquid injection nozzle mounting frame includes a long installation strip. Two screws perpendicular to the top end of the installation strip are fixedly connected to the top end of the installation strip. Two vertically penetrating circular holes are arranged on one side of the portal frame close to the servo motor. The top of each screw is inserted into the circular hole from bottom to top. A top positioning nut and a bottom positioning nut are screwed on each screw. The portal frame is clamped between the top positioning nut and the bottom positioning nut.

[0012] Among them, a chute with a "convex" cross-section is opened on one side of the installation strip close to the servo motor. A slider with a "convex" cross-section is arranged on the back of the liquid injection nozzle mounting block. The slider is in sliding fit with the chute.

[0013] Among them, a movable positioning block with a "convex" cross-section is also slidably installed in the sliding groove. A second strip-shaped hole is opened on the side of the mounting strip away from the servo motor, and the second strip-shaped hole is parallel to the short side of the base. A positioning bolt sleeved in the second strip-shaped hole is screwed on the back of the movable positioning block; a fixed positioning block protruding outward is also provided on the side of the mounting strip close to the servo motor. The fixed positioning block, eight liquid injection nozzle mounting blocks, and the movable positioning block are sequentially connected in series by a scissor-type telescopic frame, and the scissor-type telescopic frame is respectively connected to the fixed positioning block, eight liquid injection nozzle mounting blocks, and the movable positioning block with screws.

[0014] Further, the top of the reagent tank is covered with a tank cover. Eight strip-shaped hose sockets arranged in a line are opened on the side of the tank cover close to the servo motor, and a second hose is inserted into each hose socket; a liquid replenishing port for adding reagents to the reagent tank is also opened on the tank cover.

[0015] Further, a concave liquid collecting tank is arranged at the inner bottom of the reagent tank directly below the hose socket.

[0016] The beneficial effects of the present utility model are as follows: A liquid injection nozzle mounting rack capable of adjusting up and down is installed on the side of the gantry frame close to the servo motor. Eight liquid injection nozzle mounting blocks capable of adjusting positions along the short side of the base are installed on the liquid injection nozzle mounting rack. A vertically downward liquid injection nozzle is installed in each liquid injection nozzle mounting block. The height of the liquid injection nozzle is indirectly adjusted by adjusting the height of the liquid injection nozzle mounting rack, and the distance between the liquid injection nozzles is indirectly adjusted by adjusting the distance between the liquid injection nozzle mounting blocks, so as to be able to dispense in vitro diagnostic reagents into in vitro diagnostic reagent dispensing tubes of different specifications. Description of the Drawings

[0017] The drawings described herein are used to provide a further understanding of the present utility model and constitute a part of this application. The schematic embodiments of the present utility model and their descriptions are used to explain the present utility model and do not constitute an improper limitation to the present utility model. In the drawings:

[0018] Figure 1 is a structural schematic diagram of the in vitro diagnostic reagent dispensing device in the present utility model;

[0019] Figure 2 is a structural schematic diagram of the assembly of the tray, lead screw and guiding mechanism in the present utility model;

[0020] Figure 3 is a structural schematic diagram of the assembly of the gantry frame, reagent tank, tank cover, metering pump, liquid injection nozzle mounting rack, liquid injection nozzle mounting block, liquid injection nozzle, first hose, second hose and scissor-type telescopic frame in the present utility model;

[0021] Figure 4 is a structural schematic diagram of the gantry frame in the present utility model;

[0022] Figure 5 It is a schematic structural view after sectioning the reagent tank and the tank cover in the present utility model;

[0023] Figure 6 It is a schematic structural view of the first perspective after assembling the liquid injection nozzle mounting bracket, the liquid injection nozzle mounting block, the liquid injection nozzle and the scissor-type telescopic bracket in the present utility model;

[0024] Figure 7 It is a schematic structural view of the second perspective after assembling the liquid injection nozzle mounting bracket, the liquid injection nozzle mounting block, the liquid injection nozzle and the scissor-type telescopic bracket in the present utility model;

[0025] Figure 8 It is a schematic structural view of the liquid injection nozzle mounting block in the present utility model;

[0026] Explanation of the reference numerals in the figure: base 1, mounting plate 2, first elongated hole 201, servo motor 3, lead screw 4, screw rod 401, lead screw nut 402, guiding mechanism 5, guiding rod 501, guiding block 502, tray 6, limiting flange 601, coupling 7, gantry frame 8, round hole 801, reagent tank 9, liquid collecting tank 901, metering pump 10, liquid injection nozzle mounting bracket 11, mounting strip 1101, chute 11011, second elongated hole 11012, fixed positioning block 11013, screw 1102, upper positioning nut 1103, lower positioning nut 1104, movable positioning block 1105, positioning bolt 1106, liquid injection nozzle mounting block 12, slider 1201, liquid injection nozzle 13, first hose 14, second hose 15, locking bolt 16, pedestal bearing 17, scissor-type telescopic bracket 18, tank cover 19, hose socket 1901, liquid replenishing port 1902. Specific embodiments

[0027] The present utility model will be described in detail below with reference to the accompanying drawings and in conjunction with embodiments.

[0028] As Figures 1 to 8 shown, an in vitro diagnostic reagent dispensing device includes a rectangular base 1, on which a mounting plate 2 capable of adjusting its position along the short side direction of the base 1 is installed. Six first elongated holes 201 parallel to the short side of the base 1 are provided on the mounting plate 2. N locking bolts 16 are screwed on the base 1, and one locking bolt 16 is inserted into each first elongated hole 201. Loosening the locking bolts 16 can move the mounting plate 2, and tightening the locking bolts 16 can relatively fix the position between the mounting plate 1 and the base 1.

[0029] A servo motor 3, a lead screw 4 and a guiding mechanism 5 are installed on the mounting plate 2. The motor shaft of the servo motor 3 is connected to one end of the screw rod 401 of the lead screw 4 through a coupling 7. A tray 6 for placing in vitro diagnostic reagent dispensing tubes is installed on the lead screw 4 and the guiding mechanism 5. Specifically, the lead screw 4 includes a screw rod 401 and a lead screw nut 402 that are screwed together. Both ends of the screw rod 401 are installed on the mounting plate 2 through a set of pedestal bearings 17 respectively. The lead screw nut 402 is installed at the bottom end of the tray 6 with screws. The guiding mechanism 5 includes a guiding rod 501 and a guiding block 502. The guiding block 502 is sleeved on the guiding rod 501. Both ends of the guiding rod 501 are installed on the mounting plate 2 through a set of pedestal bearings 17 respectively. The guiding block 502 is installed at the bottom end of the tray 6 with screws. When the servo motor 3 works, it drives the screw rod 401 to rotate, thereby driving the lead screw nut 402 and the tray to move along the guiding rod, and adjusting the position of the in vitro diagnostic reagent dispensing tubes placed on the tray, so as to perform row-by-row dispensing on the in vitro diagnostic reagent dispensing tubes placed on the tray.

[0030] A circumferential upwardly protruding limiting flange 601 is provided around the tray 6, and the limiting flange 601 is used to align and position the tube rack inserted with the in vitro diagnostic reagent dispensing tubes.

[0031] A gantry 8 is also installed on the base 1. A liquid injection nozzle mounting bracket 11 that can be adjusted up and down is installed on one side of the gantry 8 close to the servo motor 3. Specifically, the liquid injection nozzle mounting bracket 11 includes a long strip-shaped mounting strip 1101. Two screw rods 1102 perpendicular to the top end of the mounting strip 1101 are fixedly connected to the top end of the mounting strip 1101. Two vertically penetrating circular holes 801 are provided on one side of the gantry 8 close to the servo motor 3. The top of each screw rod 1102 is inserted into the circular hole 801 from bottom to top. A top positioning nut 1103 and a bottom positioning nut 1104 are screwed on each screw rod 1102. The gantry 8 is clamped between the top positioning nut 1103 and the bottom positioning nut 1104. By rotating the top positioning nut 1103 and the bottom positioning nut 1104, the positions of the top positioning nut 1103 and the bottom positioning nut 1104 on the screw rod 1102 are adjusted, thereby adjusting the height of the mounting strip 1101.

[0032] Eight liquid injection nozzle mounting blocks 12 capable of adjusting their positions along the short side direction of the base 1 are mounted on the liquid injection nozzle mounting frame 11. A chute 11011 with a "convex" cross-section is provided on one side of the mounting strip 1101 close to the servo motor 3. A slider 1201 with a "convex" cross-section is provided on the back of the liquid injection nozzle mounting block 12. The slider 1201 is in sliding fit with the chute 11011. An active positioning block 1105 with a "convex" cross-section is also slidably mounted in the chute 11011. A second strip-shaped hole 11012 is provided on the side of the mounting strip 1101 away from the servo motor 3, and the second strip-shaped hole 11012 is parallel to the short side of the base 1. A positioning bolt 1106 sleeved in the second strip-shaped hole 11012 is screwed on the back of the active positioning block 1105. A fixed positioning block 11013 protruding outward is also provided on the side of the mounting strip 1101 close to the servo motor 3. The fixed positioning block 11013, the eight liquid injection nozzle mounting blocks 12, and the active positioning block 1105 are successively connected in series by a scissor-type telescopic frame 18. The scissor-type telescopic frame 18 is respectively connected to the fixed positioning block 11013, the eight liquid injection nozzle mounting blocks 12, and the active positioning block 1105 with screws. Loosen the positioning bolt 1106 to move the position of the active positioning block 1105, so as to change the telescopic length of the scissor-type telescopic frame 18, and then adjust the distance between two adjacent liquid injection nozzle mounting blocks 12. After the position of the liquid injection nozzle mounting block is adjusted, tighten the positioning bolt 1106 to make the position between the liquid injection nozzle mounting block and the mounting strip 1101 relatively fixed.

[0033] A reagent tank 9 for loading reagents and eight metering pumps 10 are mounted at the top of the gantry frame 8. A vertically downward liquid injection nozzle 13 is mounted in each liquid injection nozzle mounting block 12. The top of the liquid injection nozzle 13 is connected to the outlet of the metering pump 10 through a first hose 14, and the inlet of the metering pump 10 is connected to the reagent tank 9 through a second hose 15.

[0034] The top of the reagent tank 9 is covered with a tank cover 19. Eight hose sockets 1901 arranged in a line are provided on the side of the tank cover 19 close to the servo motor 3. A second hose 15 is inserted into each hose socket 1901. A liquid replenishing port 1902 for adding reagents to the reagent tank 9 is also provided on the tank cover 19. A concave liquid collecting tank 901 is provided at the inner bottom of the reagent tank 9 directly below the hose socket 1901. The liquid collecting tank 901 facilitates the collection of in vitro diagnostic reagents at the bottom of the reagent tank 9.

[0035] The above shows and describes the basic principles, main features and advantages of the present invention. Those skilled in the art should understand that the present invention is not limited by the above embodiments. What is described in the above embodiments and the specification only illustrates the principles of the present invention. Without departing from the spirit and scope of the present invention, the present invention will have various changes and improvements, and these changes and improvements all fall within the scope of the present invention claimed.

Claims

1. An in vitro diagnostic reagent dispensing device, characterized in that: It includes a rectangular base, on which there is an installation plate that can be adjusted in position along the short side direction of the base. A servo motor, a lead screw, and a guiding mechanism are installed on the installation plate. A tray for placing in vitro diagnostic reagent dispensing tubes is installed on the lead screw and the guiding mechanism. The motor shaft of the servo motor is connected to one end of the lead screw through a coupling. A gantry is also installed on the base. At the top of the gantry, there is a reagent tank for loading reagents and eight metering pumps. On one side of the gantry close to the servo motor, there is a liquid injection nozzle mounting bracket that can be adjusted up and down. On the liquid injection nozzle mounting bracket, there are eight liquid injection nozzle mounting blocks that can be adjusted in position along the short side direction of the base. A vertically downward liquid injection nozzle is installed in each liquid injection nozzle mounting block. The top of the liquid injection nozzle is connected to the outlet of the metering pump through a first hose, and the inlet of the metering pump is connected to the reagent tank through a second hose.

2. The in vitro diagnostic reagent dispensing device according to claim 1, wherein: N first strip-shaped holes parallel to the short side of the base are opened on the installation plate, and N locking bolts are screwed on the base. One locking bolt is inserted into each first strip-shaped hole.

3. The in vitro diagnostic reagent dispensing device according to claim 1, wherein: The lead screw includes a screw rod and a lead screw nut that are screwed together. The two ends of the screw rod are respectively installed on the installation plate through a set of pedestal bearings, and the lead screw nut is installed at the bottom end of the tray with screws.

4. The in vitro diagnostic reagent dispensing device according to claim 1, wherein: The guiding mechanism includes a guiding rod and a guiding block. The guiding block is sleeved on the guiding rod. The two ends of the guiding rod are respectively installed on the installation plate through a set of pedestal bearings, and the guiding block is installed at the bottom end of the tray with screws.

5. The in vitro diagnostic reagent dispensing device according to claim 1, characterized in that: A circle of upwardly protruding limiting flanges is arranged around the tray.

6. The in vitro diagnostic reagent dispensing device according to claim 1, wherein: The liquid injection nozzle mounting bracket includes a long strip-shaped mounting strip. At the top end of the mounting strip, there are two screw rods perpendicular to the top end of the mounting strip. On one side of the gantry close to the servo motor, there are two round holes that penetrate up and down. The top of the screw rod is inserted into the round hole from bottom to top. A top positioning nut and a bottom positioning nut are screwed on each screw rod, and the gantry is clamped between the top positioning nut and the bottom positioning nut.

7. The in vitro diagnostic reagent dispensing device according to claim 6, wherein: On one side of the mounting strip close to the servo motor, a chute with a "convex" cross-section is opened. On the back of the liquid injection nozzle mounting block, there is a slider with a "convex" cross-section. The slider is slidably matched with the chute.

8. The in vitro diagnostic reagent dispensing device according to claim 7, characterized in that: An activity positioning block with a "convex" cross-section is also slidably installed in the chute. On the side of the mounting strip away from the servo motor, a second strip-shaped hole is opened, and the second strip-shaped hole is parallel to the short side of the base. A positioning bolt sleeved in the second strip-shaped hole is screwed on the back of the activity positioning block. On the side of the mounting strip close to the servo motor, there is also a protruding fixed positioning block. The fixed positioning block, the eight liquid injection nozzle mounting blocks, and the activity positioning block are sequentially connected in series by a scissor-type telescopic frame. The scissor-type telescopic frame is respectively connected to the fixed positioning block, the eight liquid injection nozzle mounting blocks, and the activity positioning block with screws.

9. The in vitro diagnostic reagent dispensing device according to claim 1, wherein: The top of the reagent tank is covered with a tank cover. On the tank cover, eight hose sockets arranged in a line are opened on the side close to the servo motor. A second hose is inserted into each hose socket. A liquid replenishing port for adding reagents to the reagent tank is also opened on the tank cover.

10. The in vitro diagnostic reagent dispensing device according to claim 9, characterized in that: At the inner bottom of the reagent tank, a concave liquid collecting tank is arranged directly below the hose socket.

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