Suspension cell fluid infusion rack

Abstract

The utility model discloses a suspension cell fluid infusion rack, which relates to the technical field of cell fluid infusion racks and comprises a fluid infusion support frame, a disposable fluid infusion consumable used for infusion is sleeved on the fluid infusion support frame, a culture fluid bag is inserted on one side of the disposable fluid infusion consumable, and a fluid infusion bag is inserted on the other side of the disposable fluid infusion consumable. An elastic buckle is fixedly connected between the culture solution bag and the disposable liquid supplementing consumable in a clamped mode, and the problems that according to an existing liquid supplementing mode, liquid leakage and damage of the culture bag are likely to be caused, and even backflow is likely to be caused are solved. The funnel is arranged on the syringe needle cylinder, so that the funnel can be inserted into the syringe needle cylinder from the upper end for fluid infusion, the syringe needle cylinder and the funnel are combined to form a disposable integral consumable and are independently packaged, the cell culture fluid is prevented from being polluted, and the connection part of the culture fluid bag and the disposable fluid infusion consumable can be elastically extruded through the arrangement of the elastic buckle; the connection looseness between the culture solution bag and the disposable fluid infusion consumable is avoided during fluid infusion, and the operation is convenient.

Description

Technical Field

[0001] The utility model relates to the technical field of cell fluid replenishing racks, in particular to a suspension cell fluid replenishing rack. Background Technique

[0002] In recent years, the immunocyte therapy technology has developed rapidly and attracted much attention. It is the fourth tumor treatment method after surgery, radiotherapy, and chemotherapy. The immunocyte therapy technology is to collect adult peripheral blood, umbilical cord blood, or placental blood, isolate and obtain immunocytes, and through in vitro induction and culture, make them proliferate in large numbers. During the large-scale in vitro amplification and culture of immunocytes, a large amount of fresh culture medium usually needs to be supplemented to meet the nutritional components necessary for cell growth.

[0003] When a large amount of fresh culture medium is needed for fluid replenishment, due to the limitations of the space of the ultra-clean workbench and the volume of fluid replenishment, the culture bag is usually placed flat on the ultra-clean workbench. The left hand uses a hemostat to clamp the catheter of the cell culture bag, and the right hand directly pours the culture medium. However, this method has poor fluidity of the liquid, and the experimenter needs to repeatedly pat the culture bag, which is very likely to cause leakage and breakage of the culture bag, and even may cause backflow, greatly increasing the risk of cell contamination and the difficulty of technical operation.

[0004] In view of the above problems, a suspension cell fluid replenishing rack is proposed. Content of the Utility Model

[0005] The purpose of the utility model is to provide a suspension cell fluid replenishing rack, which solves the problems in the background technique that the existing fluid replenishing method has poor fluidity of the liquid, the experimenter needs to repeatedly pat the culture bag, which is very likely to cause leakage and breakage of the culture bag, and even may cause backflow, greatly increasing the risk of cell contamination and the difficulty of technical operation.

[0006] To achieve the above purpose, the utility model provides the following technical solution: A suspension cell fluid replenishing rack, including a disposable fluid replenishing consumable for infusion sleeved on a fluid replenishing support frame, a culture medium bag is inserted on one side of the disposable fluid replenishing consumable, an elastic buckle is fixedly clamped between the culture medium bag and the disposable fluid replenishing consumable, the fluid replenishing support frame includes a fixing plate placed on the ground and a Z-shaped frame inserted inside the fixing plate, the disposable fluid replenishing consumable includes a syringe barrel inserted inside the Z-shaped frame, a funnel is placed on the upper end of the syringe barrel, and the elastic buckle includes a fixing frame and an elastic clamping frame elastically clamped at the connection between the culture medium bag and the disposable fluid replenishing consumable.

[0007] Preferably, the culture medium bag includes a base liquid storage bag, an output pipe fixed in the middle of one side of the base liquid storage bag, and a liquid inlet pipe connected to one side of the base liquid storage bag for facilitating fluid replenishment.

[0008] Preferably, a bayonet is provided at the upper end of the fixing plate, and the lower end of the Z-shaped frame is horizontally inserted into the bayonet.

[0009] Preferably, an indication mark is provided on the syringe barrel, an infusion hose is provided at the lower end of the syringe barrel, and a limiting rubber sleeve is provided at the upper end of the joint between the syringe barrel and the Z-shaped frame.

[0010] Preferably, the upper end of the syringe barrel is provided with an inclined mouth, and a horizontal rubber sleeve is sleeved at the inclined mouth.

[0011] Preferably, the elastic buckle further includes two sets of elastic kits sleeved inside the funnel. The elastic kits include inserting rods inserted into the elastic card holder and energy storage springs sleeved on the inserting rods.

[0012] Preferably, the fixing frame includes a spring groove and a second circular frame fixed on one side of the spring groove for sleeving the infusion hose.

[0013] Preferably, the elastic card holder includes a slider slidably sleeved inside the spring groove, and a first circular frame is fixedly arranged at the upper end of the slider.

[0014] Compared with the prior art, the beneficial effects of the present utility model are as follows:

[0015] 1. A suspension cell fluid infusion rack provided by the present utility model, through the setting of a disposable fluid infusion consumable, enables the funnel to be inserted into the syringe barrel from the upper end for fluid infusion. The syringe barrel and the funnel together form a disposable integral consumable, which is independently packaged to ensure that the cell culture solution is not contaminated, and solves the problems that the existing fluid infusion method has poor fluidity, greatly increasing the risk of cell contamination and the difficulty of technical operation.

[0016] 2. A suspension cell fluid infusion rack provided by the present utility model, through the setting of the elastic buckle, enables the connection between the culture solution bag and the disposable fluid infusion consumable to be elastically squeezed, avoiding the loosening of the connection between the culture solution bag and the disposable fluid infusion consumable during fluid infusion, and is convenient for operation, solving the problems that the existing fluid infusion method requires the experimenter to repeatedly pat the culture bag, which is likely to cause leakage and damage of the culture bag, and even may cause backflow. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 is a schematic diagram of the overall structure of the present utility model;

[0018] Figure 2 is a schematic diagram of the integrated side view structure of the present utility model;

[0019] Figure 3 is a schematic diagram of the structure of the culture solution bag of the present utility model;

[0020] Figure 4It is a schematic diagram of the dissected structure of the elastic buckle of the utility model;

[0021] Figure 5 It is a schematic diagram of the disassembled structure of the fluid infusion support frame and the disposable fluid infusion consumables of the utility model.

[0022] In the figure: 1. culture medium bag; 11. base liquid storage bag; 12. output tube; 13. liquid inlet tube; 2. liquid infusion support frame; 21. fixing plate; 211. bayonet; 22. Z-shaped frame; 3. disposable liquid infusion consumables; 31. syringe barrel; 311. indicator mark; 312. limit rubber sleeve; 313. horizontal rubber sleeve; 314. infusion hose; 32. funnel; 4. elastic buckle; 41. fixing frame; 411. spring groove; 412. second round frame; 42. elastic bracket; 421. slider; 422. first round frame; 43. elastic kit; 431. plug rod; 432. storage spring. DETAILED DESCRIPTION

[0023] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0024] In order to further understand the content of the utility model, the utility model is described in detail in conjunction with the accompanying drawings.

[0025] Combination Figure 1 The utility model discloses a suspension cell rehydration rack, comprising a rehydration support rack 2, on which a disposable rehydration consumable 3 for infusion is sleeved, a culture fluid bag 1 is inserted on one side of the disposable rehydration consumable 3, an elastic buckle 4 is fixedly connected between the culture fluid bag 1 and the disposable rehydration consumable 3, the rehydration support rack 2 comprises a fixed plate 21 placed on the ground, a Z-shaped frame 22 inserted in the fixed plate 21, the disposable rehydration consumable 3 comprises a syringe barrel 31 inserted in the Z-shaped frame 22, a funnel 32 is placed on the upper end of the syringe barrel 31, and the elastic buckle 4 comprises a fixed frame 41 and an elastic clamping frame 42 elastically connected at the connection between the culture fluid bag 1 and the disposable rehydration consumable 3.

[0026] Specifically, the capacity of the syringe barrel 31 is 50 ML. The funnel 32 is inserted into the syringe barrel 31 from the upper end for fluid replenishment. The syringe barrel 31 and the funnel 32 together form a disposable integrated consumable, which is independently packaged to ensure that the cell culture medium is not contaminated. The Z-shaped frame 22 is used to support the syringe barrel 31. The insertion between the fixed plate 21 and the Z-shaped frame 22 enables the Z-shaped frame 22 to be quickly fixed. The elastic socket connection between the fixed frame 41 and the elastic clamping frame 42 enables the connection between the culture solution bag 1 and the disposable fluid replenishment consumable 3 to be elastically squeezed, avoiding the loosening of the connection between the culture solution bag 1 and the disposable fluid replenishment consumable 3 during fluid replenishment and facilitating the operation.

[0027] The following further describes the present utility model in conjunction with embodiments.

[0028] Embodiment 1:

[0029] Combined with Figures 2 - 5 , the culture solution bag 1 includes a base solution storage bag 11, an output pipe 12 fixed to the middle of one side of the base solution storage bag 11, and a liquid inlet pipe 13 connected to one side of the base solution storage bag 11 for facilitating fluid replenishment. The base solution storage bag 11 is placed flat on the workbench, containing cells and cell culture medium. The output pipe 12 facilitates the pouring out of the solution inside the base solution storage bag 11, and the liquid inlet pipe 13 facilitates the replenishment of the solution inside the base solution storage bag 11 during cell culture.

[0030] A bayonet 211 is opened at the upper end of the fixed plate 21. The lower end of the Z-shaped frame 22 is horizontally inserted into the bayonet 211. The fixed plate 21 is placed on the workbench. The setting of inserting the Z-shaped frame 22 into the bayonet 211 realizes the support and fixation of the Z-shaped frame 22. At the same time, the operation of inserting the syringe barrel 31 into the Z-shaped frame 22 can balance the supporting force of the fluid replenishment support frame 2 and maintain the stability of the fluid replenishment support frame 2.

[0031] An indication mark 311 is provided on the syringe barrel 31. An infusion hose 314 is provided at the lower end of the syringe barrel 31. A limit rubber sleeve 312 is provided at the upper end of the socket between the syringe barrel 31 and the Z-shaped frame 22. The limit rubber sleeve 312 limits the socket position of the syringe barrel 31, enabling the infusion hose 314 to be set at the lowest output point of the syringe barrel 31, avoiding the complete discharge of the cell culture medium during fluid replenishment. The indication mark 311 indicates the amount of the replenishing liquid in the syringe barrel 31.

[0032] The upper end of the syringe barrel 31 is set as an inclined mouth, and a horizontal rubber sleeve 313 is sleeved at the inclined mouth. The setting of the horizontal rubber sleeve 313 makes the upper surface of the syringe barrel 31 horizontal after it is inserted into the Z-shaped frame 22, providing a horizontal support for the funnel 32 and facilitating the vertical fluid replenishment of the funnel 32.

[0033] Embodiment 2:

[0034] Combined with Figure 4The elastic buckle 4 also includes two sets of elastic kits 43 sleeved inside the funnel 32. The elastic kit 43 includes an insertion rod 431 inserted into the elastic card frame 42, and a force storage spring 432 sleeved on the insertion rod 431. The insertion rod 431 provides a plug-in guide for the elastic card frame 42, and the force storage spring 432 provides an extrusion elastic force for the elastic card frame 42. Under the action of the force storage spring 432, the elastic card frame 42 can slide along the fixed frame 41 to squeeze the infusion hose 314 set between the fixed frame 41 and the elastic card frame 42, and the infusion hose 314 and the liquid inlet pipe 13 are sleeved with each other.

[0035] The fixing frame 41 includes a spring groove 411 and a second round frame 412 fixed to one side of the spring groove 411 for sleeve-engaging the infusion hose 314 . The elastic bracket 42 is slidably disposed in the spring groove 411 , and the second round frame 412 sleeves the side end of the infusion hose 314 .

[0036] The elastic bracket 42 includes a slider 421 slidably sleeved inside the spring groove 411, a first circular frame 422 is fixedly provided on the upper end of the slider 421, the second circular frame 412 and the elastic bracket 42 form a complete circle, the slider 421 and the elastic kit 43 are sleeved with each other, the first circular frame 422 is arranged at the side end, when the elastic bracket 42 squeezes the elastic kit 43, the infusion hose 314 can be inserted between the second circular frame 412 and the first circular frame 422.

[0037] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device.

[0038] Although the embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A suspension cell fluid replenishment rack, comprising a fluid replenishment support frame (2), characterized in that: A disposable fluid infusion consumable (3) for infusion is sleeved on the fluid infusion support frame (2), a culture fluid bag (1) is inserted on one side of the disposable fluid infusion consumable (3), and an elastic buckle (4) is fixedly clamped between the culture fluid bag (1) and the disposable fluid infusion consumable (3); The fluid infusion support frame (2) comprises a fixed plate (21) placed on the ground, a Z-shaped frame (22) inserted into the fixed plate (21), the disposable fluid infusion consumable (3) comprises a syringe barrel (31) inserted into the Z-shaped frame (22), a funnel (32) is placed on the upper end of the syringe barrel (31), and the elastic buckle (4) comprises a fixed frame (41) and an elastic clamping frame (42) elastically clamped at the connection between the culture fluid bag (1) and the disposable fluid infusion consumable (3).

2. The floating cell fluid replenishing rack according to claim 1, wherein: The culture liquid bag (1) comprises a base liquid storage bag (11), an output tube (12) fixed in the middle of one side of the base liquid storage bag (11), and a liquid inlet tube (13) connected to one side of the base liquid storage bag (11) for easy liquid replenishment.

3. The suspension cell rehydration rack according to claim 1, wherein: The upper end of the fixing plate (21) is provided with a bayonet (211), and the lower end of the Z-shaped frame (22) is horizontally inserted into the bayonet (211).

4. A suspension cell rehydration rack according to claim 1, characterized in that: The syringe barrel (31) is provided with an indication mark (311), the lower end of the syringe barrel (31) is provided with an infusion hose (314), and the upper end of the sleeve joint between the syringe barrel (31) and the Z-shaped frame (22) is provided with a limiting rubber sleeve (312).

5. A suspension cell rehydration rack according to claim 1, characterized in that: The upper end of the syringe barrel (31) is arranged as an oblique opening, and a horizontal rubber sleeve (313) is sleeved on the oblique opening.

6. The suspension cell rehydration rack according to claim 1, characterized in that: The elastic buckle (4) further comprises two sets of elastic kits (43) sleeved inside the funnel (32), and the elastic kits (43) comprise an insertion rod (431) inserted into the elastic bracket (42) and a force storage spring (432) sleeved on the insertion rod (431).

7. The floating cell fluid replenishing rack according to claim 1, wherein: The fixing frame (41) comprises a spring groove (411) and a second round frame (412) fixed on one side of the spring groove (411) and used for sleeve-connecting an infusion hose (314).

8. The floating cell rehydration rack according to claim 7, characterized in that: The elastic bracket (42) comprises a sliding block (421) which is slidably sleeved inside the spring groove (411), and a first round frame (422) is fixedly arranged on the upper end of the sliding block (421).

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