Liquid separation device

Abstract

The utility model relates to the technical field of experimental instruments, and discloses a liquid separation device which comprises an outer tube, a liquid separation tube and a liquid separation tube, the inner pipe is detachably arranged in the outer pipe in a penetrating mode, a liquid drainage thin pipe is arranged at the end, penetrating into the outer pipe from the opening, of the inner pipe, the liquid drainage thin pipe abuts against the end, away from the opening, of the outer pipe in a sealed mode or is away from the end, away from the opening, of the outer pipe, and the inner pipe is suitable for containing external fluid; and the pressure adjusting structure is arranged on the inner pipe and is suitable for changing the air pressure in the inner pipe and adjusting the on-off of the liquid discharging thin pipe. The inner pipe and the outer pipe which are sleeved with each other are arranged, the anti-leakage requirement when the inner pipe is filled with external fluid is met, and fluid gradient centrifugal layering can be carried out. The pressure adjusting structure is arranged on the inner pipe and matched with the liquid discharging thin pipe arranged at the end of the inner pipe, under the capillary action and adjustment of pressure difference, on-off of external fluid flowing out of the liquid discharging thin pipe is autonomously controlled, and gradient liquid of different levels is accurately discharged.

Description

Technical Field

[0001] The utility model relates to the technical field of experimental instruments, and particularly relates to a liquid separation device. Background Art

[0002] During the experiment process in the fields of biomedicine, chemistry, etc., it is often necessary to separate different gradient liquid components after natural static settling or centrifugal stratification of suspensions with different fine components. However, the commonly used separating funnel structure has complex operations, cannot be centrifuged, and cannot meet the requirements of disposable aseptic operation for some biological and medical technologies.

[0003] At present, although the commonly applicable single-chamber centrifuge tube can stratify the suspension through centrifugal motion, on the one hand, it still needs to cooperate with external instruments, such as pipettes and other tools, to achieve the extraction of different gradient liquids, which is inconvenient to operate. On the other hand, the accuracy during liquid separation is relatively low, and it is easy to mix with other layers, making it difficult to meet the requirements of efficient and precise experiments. Summary of the Utility Model

[0004] In view of this, the utility model provides a liquid separation device to solve the problems of inconvenient operation and low liquid separation accuracy during the separation of different gradient liquids of the suspension in the prior art.

[0005] In a first aspect, the utility model provides a liquid separation device, including: an outer tube with one end open; an inner tube detachably inserted into the outer tube, a drain capillary tube is arranged at one end of the inner tube that penetrates into the outer tube from the open end, the drain capillary tube is in sealed contact with or separated from the end of the outer tube away from the open end, and the inner tube is suitable for storing external fluid; a pressure regulating structure arranged on the inner tube, suitable for changing the internal air pressure of the inner tube and regulating the on-off of the drain capillary tube.

[0006] Beneficial Effects:

[0007] The mutually sleeved inner and outer tubes are provided. When the outer tube is in sealed contact with the drain capillary tube, it meets the anti-leakage requirement when the inner tube is filled with external fluid, and can stratify the external fluid gradient during centrifugal motion. At the same time, a pressure regulating structure is arranged on the inner tube. When it is necessary to extract and transfer the gradient stratified liquid, the inner tube is away from the outer tube, and the internal air pressure in the inner tube is regulated through the pressure regulating structure. Cooperating with the drain capillary tube arranged at the end of the inner tube, under the regulation of capillary action and pressure difference, the on-off of the outflow of external fluid from the drain capillary tube is independently controlled, and different levels of gradient liquids are accurately discharged. With such a setting, there is no need to cooperate with external instruments such as pipettes. A single liquid separation device can achieve centrifugation, separation, and extraction of gradient liquids, and independently regulate the on-off of liquid discharge, which is convenient for accurately controlling liquid separation and improving the liquid separation accuracy.

[0008] In an alternative embodiment, the pressure regulating structure includes: a cover body detachably connected to an end of the inner tube away from the liquid discharge thin tube; a pressure regulating hole provided on the cover body and communicating with the inside of the inner tube, having a flow blocking state when externally sealed and blocked, and a liquid discharge state when open.

[0009] In an alternative embodiment, a limiting groove is provided on the inner bottom wall of the outer tube, and the limiting groove is adapted to correspondingly accommodate and seal and limit the end of the liquid discharge thin tube.

[0010] In an alternative embodiment, the liquid distribution device further includes: a guiding surface provided on the inner bottom wall of the outer tube, inclined along the circumference of the limiting groove, and the inner diameter of the guiding surface gradually decreases along the direction towards the limiting groove.

[0011] In an alternative embodiment, the liquid distribution device further includes: a first limiting portion provided on the inner wall of the outer tube; a first limiting and cooperating portion provided on the outer wall of the inner tube, detachably and limitably connected to the first limiting portion.

[0012] In an alternative embodiment, the first limiting portion is provided on the inner tube, and at least a part of the inner tube between the first limiting portion and the pressure regulating structure is exposed outside the outer tube.

[0013] In an alternative embodiment, the length directions of the outer tube and the inner tube are arranged in the same direction; along the length direction of the outer tube, the distance between the first limiting portion and the end of the liquid discharge thin tube is set to be equal to the distance between the first limiting and cooperating portion and the limiting groove.

[0014] In an alternative embodiment, along the length direction of the inner tube, the inner diameter of the end of the inner tube penetrating into the outer tube gradually decreases, and the liquid discharge thin tube is correspondingly connected to the position where the inner diameter of the inner tube is the smallest.

[0015] In an alternative embodiment, the inner tube and the outer tube are made of a transparent material.

[0016] In an alternative embodiment, the inner tube and the outer tube are respectively provided with scale marks along their respective length directions. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] In order to more clearly illustrate the specific embodiments of the present invention or the technical solutions in the prior art, the following will briefly introduce the drawings required for use in the description of the specific embodiments or the prior art. Obviously, the following drawings are some embodiments of the present invention. For those of ordinary skill in the art, other drawings can be obtained based on these drawings without creative efforts.

[0018] Figure 1 Schematic structural diagram of a liquid separation device according to an embodiment of the present utility model;

[0019] Figure 2 is Figure 1 Exploded view of the structure of the liquid separation device shown;

[0020] Figure 3 is Figure 1 Schematic structural diagram of the working process of the liquid separation device in;

[0021] Explanation of reference numerals in the drawings:

[0022] 1. Outer tube; 11. Limit groove; 12. Guide surface; 13. First limit fitting part; 2. Inner tube; 21. First limit part; 22. Second limit fitting part; 3. Drainage thin tube; 4. Cover body; 41. Second limit part; 5. Pressure regulating hole; 6. External fluid. Specific embodiments

[0023] To make the objectives, technical solutions, and advantages of the embodiments of the present utility model clearer, the technical solutions in the embodiments of the present utility model will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present utility model. Obviously, the described embodiments are some, but not all, of the embodiments of the present utility model. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present utility model.

[0024] As Figures 1-3 , the present utility model provides a liquid separation device, including: an outer tube 1, an inner tube 2, and a pressure regulating structure.

[0025] One end of the outer tube 1 is open for the inner tube 2 to penetrate or be taken out. In this embodiment, the other end of the outer tube 1 is completely closed. As an alternative embodiment, an opening may also be provided at the other end of the outer tube 1, and only partially closed, and the closed part should be able to support the inner tube 2 and close the corresponding pipe orifice of the drainage thin tube 3 on the inner tube 2 when the inner tube 2 extends and abuts.

[0026] The inner tube 2 is detachably disposed inside the outer tube 1. When the inner tube 2 is placed inside the outer tube 1, a drainage thin tube 3 is provided at one end of the inner tube 2 that penetrates into the outer tube 1 from the open end. The drainage thin tube 3 is in sealed abutment with the end of the outer tube 1 far from the open end. During the process of taking out the inner tube 2 from the outer tube 1, the drainage thin tube 3 and the end of the outer tube 1 far from the open end move away from each other. The inside of the inner tube 2 is suitable for receiving the external fluid 6.

[0027] The pressure regulating structure is disposed on the inner tube 2. Under the action of the pressure regulating structure, the user can change the internal air pressure of the inner tube 2 and adjust the on-off of the drainage thin tube 3.

[0028] An inner tube and an outer tube that fit into each other are provided. When the outer tube 1 is in sealed contact with the liquid discharge thin tube 3, it meets the requirement of preventing leakage when the inner tube 2 is filled with an external fluid 6, and the external fluid 6 can be gradient stratified during centrifugal motion. At the same time, a pressure regulating structure is provided on the inner tube 2. When it is necessary to extract and transfer the gradient stratified liquid, the inner tube 2 is separated from the outer tube 1, and the internal pressure in the inner tube 2 is regulated through the pressure regulating structure. In cooperation with the liquid discharge thin tube 3 provided at the end of the inner tube 2, under the regulation of capillary action and pressure difference, the on-off of the outflow of the external fluid 6 from the liquid discharge thin tube 3 is autonomously controlled, and the gradient liquid of different levels is accurately discharged. With this setting, without the cooperation of external structures such as pipettes, a single liquid separation device can achieve centrifugal separation and extraction of gradient liquids, and autonomously regulate the on-off of liquid discharge, which is convenient for precise control of liquid separation and improves the accuracy of liquid separation.

[0029] In this embodiment, the pressure regulating structure includes: a cover body 4 and a pressure regulating hole 5.

[0030] One end of the inner tube 2 away from the liquid discharge thin tube 3 is provided with an opening, and the cover body 4 is detachably connected to the end of the inner tube 2 with the opening. Specifically, the two are threadedly connected. Inner threads and outer threads are respectively provided on the inner edge of the cover body 4 and the outer edge of the end of the inner tube 2 with the opening, and they can be set as a second limiting portion 41 and a second limiting cooperation portion 22. As a changeable implementation manner, the two can also be snap-connected, interference-connected, etc.

[0031] The pressure regulating hole 5 is provided on the cover body 4 and is communicated with the inside of the inner tube 2, and has a flow blocking state when blocked by an external structure and a liquid discharge state when open. In this embodiment, for the convenience of holding and operating, the external structure is the user's finger. Preferably, a groove for accommodating the finger can be provided on the periphery of the pressure regulating hole 5 for accurate positioning and to avoid slipping. In addition, the setting position of the pressure regulating hole 5 on the cover body 4 can be adjusted according to the need of finger pressing, and it can be at the center of the cover body 4 or deviate to one side.

[0032] The pressure in the inner tube 2 is adjusted by pressing through the opening. The simple structure realizes detachable connection, and without setting complex switch parts, it can achieve the effect of separating and discharging liquid. The structure is simple, the implementation is convenient, and it is easy to manufacture.

[0033] As a changeable implementation manner, the cover body 4 can be not provided, and the pressure regulating hole 5 is integrally provided with the opening of the inner tube 2. As another changeable implementation manner, the pressure regulating structure can also be a structure similar to a micro air pump or a syringe, etc.

[0034] Further preferably, to prevent external contaminants from entering the inner tube 2 through the pressure regulating hole 5 and meet the requirement of disposable sterility, a sticker can be provided on the cover body 4 to be adhesively sealed to the pressure regulating hole 5. The pressure regulating hole 5 can also be set as a tortuous pipeline, or a communicating pressure regulating hose can be installed on the pressure regulating hole 5, and the user presses the opening of the hose to adjust the on-off of the inner tube 2, etc.

[0035] In this embodiment, a limiting groove 11 is provided on the inner bottom wall of the outer tube 1, and the limiting groove 11 is adapted to correspondingly accommodate and seal the end of the liquid-discharging thin tube 3. The provision of the limiting groove 11 facilitates the accurate positioning and tight fixing of the nozzle of the liquid-discharging thin tube 3, and improves the effectiveness of the seal.

[0036] In addition, the liquid distribution device further includes a guiding surface 12, which is arranged in an arc shape and correspondingly arranged on the inner bottom wall of the outer tube 1. The guiding surface 12 inclines towards the central position along the circumferential side of the limiting groove 11, that is, inclines towards the direction of the limiting groove 11. At the same time, the inner diameter of the guiding surface 12 gradually decreases along the direction towards the limiting groove 11. Such a setting realizes the guiding of the liquid-discharging thin tube 3, and further improves the accuracy of the limiting groove 11 for positioning and accommodating the nozzle of the liquid-discharging thin tube 3.

[0037] The liquid distribution device further includes: a first limiting portion 21 and a first limiting and cooperating portion 13.

[0038] The first limiting portion 21 is provided on one of the inner wall of the outer tube 1 and the outer wall of the inner tube 2, and the first limiting and cooperating portion 13 is provided on the other of the inner wall of the outer tube 1 and the outer wall of the inner tube 2, and is detachably and limit-connected to the first limiting portion 21. In this embodiment, both the first limiting portion 21 and the first limiting and cooperating portion 13 are thread structures, and the two are in threaded cooperation, specifically one of an internal thread and an external thread.

[0039] As an alternative embodiment, the first limiting portion 21 and the first limiting and cooperating portion 13 can also be a snap and a snap groove and are detachably snap-connected, or can be a sliding groove and a sliding block and are in sliding cooperation.

[0040] In this embodiment, the first limiting portion 21 is provided on the inner tube 2, specifically as an external thread. The inner tube 2 between the first limiting portion 21 and the pressure regulating structure has at least a part of this part of the inner tube 2 exposed outside the outer tube 1. Such a setting makes a part of the inner tube 2 exposed, which is convenient for the user to hold and twist to separate the inner tube 2 and the outer tube 1.

[0041] As an alternative embodiment, the inner tube 2 between the first limiting portion 21 and the pressure regulating structure may not be exposed outside the outer tube 1. By setting the tightening and loosening twisting directions of both the first limiting portion 21 and the first limiting and cooperating portion 13 to be different from the tightening and loosening twisting direction of the cover body 4 and the inner tube 2, the user can loosen and unlock both the first limiting portion 21 and the first limiting and cooperating portion 13 by twisting the cover body 4.

[0042] Preferably, the length directions of the outer tube 1 and the inner tube 2 are arranged in the same direction, and the inner diameter of the outer tube 1 is slightly larger than the outer diameter of the inner tube 2. Further preferably, the first limiting portion 21 and the first limiting and cooperating portion 13 can allow air to pass through to balance the gas pressure at the bottom and the opening of the outer tube 1.

[0043] In this embodiment, along the length of the outer tube 1, the distance between the first stopper 21 and the end of the drainage tube 3 is equal to the distance between the first stopper 13 and the stopper groove 11. This arrangement ensures that the first stopper 21 can seal and separate the end of the drainage tube 3 from the stopper groove 11 when connected to and disconnected from the first stopper 13, facilitating precise adjustment by the user.

[0044] In this embodiment, the inner tube 2 gradually decreases in inner diameter along its length as it penetrates one end of the outer tube 1. The drainage tube 3 is connected to and positioned at the point where the inner diameter of the inner tube 2 is smallest. This arrangement facilitates the discharge of fluid from the inner tube 2 and ensures a small inner diameter for the drainage tube 3, preventing fluid leakage from the inner tube 2 and reducing the drainage flow rate. This allows for precise control of the fluid flow rate, thereby improving the accuracy of liquid separation.

[0045] Preferably, the inner tube 2 and the outer tube 1 are made of transparent materials to facilitate users to observe the flow rate of the liquid inside the inner tube 2 in real time. The specific materials of the two can be commonly used materials for biomedical consumables such as polypropylene, polystyrene, polyethylene or glass.

[0046] Further preferably, the inner tube 2 and the outer tube 1 are respectively provided with capacity scale markings along their respective length directions. Alternatively, the scale markings may be provided on only one of the inner tube 2 and the outer tube 1.

[0047] Preferably, the outer dimensions of the inner tube 2 and the outer tube 1 conform to standardized centrifuge tubes, such as 50 ml or 15 ml, to facilitate universal use in laboratory instruments and equipment. This configuration makes the outer structure similar to existing standard centrifuge tubes and can be used in all laboratory instruments and equipment without the need for additional accessories.

[0048] Working process:

[0049] During use, tighten the outer tube 1 and the inner tube 2, add the separated fluid sample into the inner tube 2, tighten the cover 4, manually seal the pressure regulating hole 5 after standing for natural stratification or centrifugal stratification, and slowly loosen the first limiting part 21 and the first limiting matching part 13 to separate the tube mouth of the discharge tube 3 from the limiting groove 11.

[0050] In addition, as needed, when it is necessary to separate the bottom layer of fluid first, the opening degree of the pressure regulating hole 5 can be controlled by fingers after loosening, so that the bottom layer of fluid falls into the outer tube 1. When the outer tube 1 is no longer needed to hold the fluid, the user can keep manually sealing the pressure regulating hole 5 during the separation process of the outer tube 1 and the inner tube 2.

[0051] After the inner tube 2 is separated, the user can manually release or block it to gradually discharge the fluids at different levels inside into the external target container to achieve liquid separation.

[0052] Although embodiments of the present utility model have been described in conjunction with the accompanying drawings, those skilled in the art can make various modifications and variations without departing from the spirit and scope of the present utility model, and such modifications and variations fall within the scope defined by the appended claims.

Claims

1. A liquid separation device, characterized in that, Including: An outer tube (1) with one end being open-ended; An inner tube (2) detachably inserted into the outer tube (1). A liquid discharge capillary tube (3) is provided at one end of the inner tube (2) that penetrates into the outer tube (1) from the open end. The liquid discharge capillary tube (3) is in sealing contact with or away from the end of the outer tube (1) far from the open end. The inner tube (2) is adapted to receive an external fluid (6); A pressure regulating structure is provided on the inner tube (2) and is adapted to change the internal air pressure of the inner tube (2) and regulate the on-off state of the liquid discharge capillary tube (3).

2. The liquid separation device according to claim 1, wherein The pressure regulating structure includes: A cover body (4) detachably connected to the end of the inner tube (2) far from the liquid discharge capillary tube (3); A pressure regulating hole (5) is provided on the cover body (4) and is in communication with the inside of the inner tube (2), having a flow blocking state when blocked by an external structure and a liquid discharge state when open.

3. The liquid separation device according to claim 1, characterized in that A limiting groove (11) is provided on the inner bottom wall of the outer tube (1), and the limiting groove (11) is adapted to correspondingly receive and seal and limit the end of the liquid discharge capillary tube (3).

4. The liquid separation device according to claim 3, characterized in that, Also included: A guiding surface (12) is provided on the inner bottom wall of the outer tube (1), inclined along the circumference of the limiting groove (11). Along the direction towards the limiting groove (11), the inner diameter of the guiding surface (12) gradually decreases.

5. The liquid separation device according to any one of claims 1-4, characterized in that, Also included: A first limiting portion (21) is provided on either the inner wall of the outer tube (1) or the outer wall of the inner tube (2); A first limiting and cooperating portion (13) is provided on the other of the inner wall of the outer tube (1) and the outer wall of the inner tube (2), detachably and limitedly connected to the first limiting portion (21).

6. The liquid separation device according to claim 5, wherein, The first limiting portion (21) is provided on the inner tube (2), and at least a part of the inner tube (2) between the first limiting portion (21) and the pressure regulating structure is exposed outside the outer tube (1).

7. The liquid separation device according to claim 5, characterized in that The length directions of the outer tube (1) and the inner tube (2) are arranged in the same direction; Along the length direction of the outer tube (1), the distance between the first limiting portion (21) and the end of the liquid discharge capillary tube (3) is equal to the distance between the first limiting and cooperating portion (13) and the limiting groove (11).

8. The liquid separation device according to any one of claims 1-4, 6-7, characterized in that Along the length direction of the inner tube (2), the inner diameter of the end of the inner tube (2) that penetrates into the outer tube (1) gradually decreases, and the liquid discharge capillary tube (3) is correspondingly connected to the position where the inner diameter of the inner tube (2) is the smallest.

9. The liquid separation device according to any one of claims 1-4, 6-7, characterized in that, The inner tube (2) and the outer tube (1) are made of a transparent material.

10. The liquid separation device according to claim 9, characterized in that, The inner tube (2) and the outer tube (1) are respectively provided with scale marks along their respective length directions.

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