Clamping mechanism for PCR (Polymerase Chain Reaction) plate
Through the combined design of the rotating seat and the vacuum adsorption plate, the problem of damage and slippage of the PCR plate during the clamping process is solved, and stable clamping protection is achieved.
Patent Information
- Application Number
- CN202422050094.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-08-22
- Publication Date
- 2025-08-01
- Estimated Expiration
- 2034-08-22
AI Technical Summary
The existing PCR plate clamping mechanism can easily cause damage and slippage of the PCR plate during clamping, and cannot effectively protect the structural integrity of the PCR plate.
The combined design of the rotating seat, PCR plate limiting plate and vacuum adsorption plate is adopted. The rotating drive assembly and vacuum adsorption assembly are used to achieve stable clamping of the PCR plate, and the vacuum pump generates a negative pressure adsorption force to fix the PCR plate, and combines the limiting plate to prevent slipping.
Effectively prevent the PCR board from being damaged by hard pressing during clamping, ensuring clamping stability and safety, and avoiding the PCR board slipping and dislocation.
Smart Images
Figure CN223175221U_ABST
Abstract
Description
Technical Field:
[0001] The utility model relates to the technical field of PCR plates, in particular to a clamping mechanism for a PCR plate. Background Art:
[0002] The basic principle of the PCR (Polymerase Chain Reaction) technology is similar to the natural DNA replication process. Its specificity depends on oligonucleotide primers complementary to both ends of the target sequence. PCR basically consists of three basic reaction steps: denaturation - annealing - extension. PCR utilizes the fact that DNA denatures into single strands at a high temperature of 95°C in vitro, primers bind to the single strands according to the principle of base complementary pairing at a low temperature (usually around 60°C), and then the temperature is adjusted to the optimal reaction temperature of DNA polymerase (around 72°C), and DNA polymerase synthesizes complementary strands along the direction from phosphate to pentose. Generally, during the heating process of a PCR plate, a clamping device is usually required for heating operations. Existing clamping mechanisms generally use mechanical arms or fixtures for squeezing clamping. Due to the small size, high precision, and highly integrated structure of the PCR plate, it is relatively fragile, and the PCR plate is easily damaged by hard extrusion during clamping. At the same time, the PCR plate is also prone to slipping during clamping. There is an urgent need for a fixed clamping mechanism for a PCR plate that can prevent clamping damage. Summary of the Utility Model:
[0003] The purpose of the utility model is to provide a clamping mechanism for a PCR plate aiming at the deficiencies of the existing technology, which can effectively prevent the PCR plate from being damaged due to excessive clamping extrusion during the clamping process and has stable clamping.
[0004] To achieve the above purpose, the technical solution adopted by the utility model is: a clamping mechanism for a PCR plate, including a rotating seat, a rotation driving component for driving the rotation of the rotating seat, two PCR plate limiting plates movably arranged horizontally below the rotating seat, a PCR plate limiting plate driving component arranged in the rotating seat for driving the two PCR plate limiting plates to move horizontally, a PCR plate vacuum adsorption plate movably arranged vertically at the bottom of the rotating seat, a PCR plate vacuum adsorption plate driving component arranged at the bottom of the rotating seat for driving the PCR plate vacuum adsorption plate to move vertically. The rotation driving component is drivingly connected to the rotating seat, the PCR plate limiting plate driving component is drivingly connected to the PCR plate limiting plates, and the PCR plate vacuum adsorption plate driving component is drivingly connected to the PCR plate vacuum adsorption plate; a vacuum pump is arranged on the PCR plate vacuum adsorption plate, an adsorption cavity and an adsorption channel are arranged in the PCR plate vacuum adsorption plate, one end of the adsorption cavity is communicated with the vacuum pump, the other end of the adsorption cavity is communicated with one end of the adsorption channel, and the other end of the adsorption channel is communicated with the outside.
[0005] A further improvement to the above solution is that a plurality of adsorption channels are provided, and the plurality of adsorption channels are arranged at equal intervals in the Y-axis direction in the PCR plate vacuum adsorption plate.
[0006] A further improvement to the above solution is that the PCR plate vacuum adsorption plate is integrally formed with the adsorption cavity and the adsorption channels.
[0007] A further improvement to the above solution is that the rotation drive assembly includes a rotation drive device and a bearing. The power output end of the rotation drive device is drivingly connected to the rotation seat, and the bearing is arranged between the rotation drive device and the rotation seat.
[0008] A further improvement to the above solution is that the PCR plate limiting plate drive assembly includes a hydraulic rod fixing seat arranged in the rotation seat, two horizontal hydraulic drive rods respectively arranged on both sides of the hydraulic rod fixing seat, and a chute arranged at the bottom of the rotation seat. The top of the PCR plate limiting plate passes through the chute and is connected to the horizontal hydraulic drive rod in the rotation seat.
[0009] A further improvement to the above solution is that rubber pads are respectively arranged at one ends of the two PCR plate limiting plates close to the PCR plate vacuum adsorption plate.
[0010] A further improvement to the above solution is that the PCR plate vacuum adsorption plate drive assembly includes a vertical hydraulic drive rod arranged at the bottom of the rotation seat. One end of the vertical hydraulic drive rod is fixedly connected to the bottom of the rotation seat, and the other end of the vertical hydraulic drive rod is drivingly connected to the PCR plate vacuum adsorption plate.
[0011] A further improvement to the above solution is that at least two vertical hydraulic drive rods are provided.
[0012] The beneficial effects of the present utility model are as follows: The present utility model includes a rotating seat, a rotation driving assembly for driving the rotation of the rotating seat, two PCR plate limiting plates movably arranged horizontally below the rotating seat, a PCR plate limiting plate driving assembly arranged inside the rotating seat for driving the two PCR plate limiting plates to move horizontally, a PCR plate vacuum adsorption plate movably arranged vertically at the bottom of the rotating seat, and a PCR plate vacuum adsorption plate driving assembly arranged at the bottom of the rotating seat for driving the PCR plate vacuum adsorption plate to move vertically. The rotation driving assembly is drivingly connected to the rotating seat, the PCR plate limiting plate driving assembly is drivingly connected to the PCR plate limiting plates, and the PCR plate vacuum adsorption plate driving assembly is drivingly connected to the PCR plate vacuum adsorption plate; A vacuum pump is arranged on the PCR plate vacuum adsorption plate, and an adsorption cavity and an adsorption channel are arranged inside the PCR plate vacuum adsorption plate. One end of the adsorption cavity is communicated with the vacuum pump, the other end of the adsorption cavity is communicated with one end of the adsorption channel, and the other end of the adsorption channel is communicated with the outside;
[0013] By arranging a PCR plate limiting plate driving assembly to drive the PCR plate limiting plates to move horizontally, and arranging a PCR plate vacuum adsorption plate driving assembly to drive the PCR plate vacuum adsorption plate to move vertically. When it is necessary to clamp the PCR plate, the PCR plate limiting plates are adjusted to the width or length of the PCR plate through the PCR plate limiting plate driving assembly, the PCR plate vacuum adsorption plate moves to the position of the PCR plate, a negative pressure is formed in the adsorption cavity by pumping with the vacuum pump, and the adsorption channel generates an adsorption force to adsorb the PCR under the PCR plate vacuum adsorption plate. At the same time, the PCR plate limiting plates prevent the PCR plate from slipping. Clamping through vacuum adsorption can effectively protect the structure of the PCR plate and prevent the PCR plate from being damaged by hard extrusion when being clamped. Description of the drawings:
[0014] Figure 1 It is a schematic structural diagram of the present utility model.
[0015] Figure 2 It is a bottom view of the rotating seat of the present utility model.
[0016] Figure 3 It is a bottom view of the vacuum adsorption plate of the present utility model.
[0017] Description of the reference numerals: Rotating seat 1, rotation driving assembly 2, rotation driving device 21, bearing 22, PCR plate limiting plate 3, rubber pad 31, PCR plate limiting plate driving assembly 4, hydraulic rod fixing seat 41, horizontal hydraulic driving rod 42, sliding groove 43, PCR plate vacuum adsorption plate 5, vacuum pump 51, adsorption cavity 52, adsorption channel 53, PCR plate vacuum adsorption plate driving assembly 6, vertical hydraulic driving rod 61. Detailed implementation manners:
[0018] The following further describes the present utility model in conjunction with the accompanying drawings. As Figures 1-3 shown, the present utility model provides a clamping mechanism for a PCR plate, including a rotating seat 1, a rotation driving assembly 2 for driving the rotation of the rotating seat 1, two PCR plate limiting plates 3 movably arranged horizontally below the rotating seat 1, a PCR plate limiting plate driving assembly 4 arranged inside the rotating seat 1 for driving the two PCR plate limiting plates 3 to move horizontally, a PCR plate vacuum adsorption plate 5 movably arranged vertically at the bottom of the rotating seat 1, and a PCR plate vacuum adsorption plate driving assembly 6 arranged at the bottom of the rotating seat 1 for driving the PCR plate vacuum adsorption plate 5 to move vertically. The rotation driving assembly 2 is drivingly connected to the rotating seat 1, the PCR plate limiting plate driving assembly 4 is drivingly connected to the PCR plate limiting plates 3, and the PCR plate vacuum adsorption plate driving assembly 6 is drivingly connected to the PCR plate vacuum adsorption plate 5. A vacuum pump 51 is provided on the PCR plate vacuum adsorption plate 5. An adsorption cavity 52 and an adsorption channel 53 are arranged inside the PCR plate vacuum adsorption plate 5. One end of the adsorption cavity 52 is communicated with the vacuum pump 51, the other end of the adsorption cavity 52 is communicated with one end of the adsorption channel 53, and the other end of the adsorption channel 53 is communicated with the outside. By setting the PCR plate limiting plate driving assembly 4 to drive the PCR plate limiting plates 3 to move horizontally and setting the PCR plate vacuum adsorption plate driving assembly 6 to drive the PCR plate vacuum adsorption plate 5 to move vertically, when it is necessary to clamp the PCR plate, the PCR plate limiting plates 3 are adjusted to the width or length of the PCR plate through the PCR plate limiting plate driving assembly 4. The PCR plate vacuum adsorption plate 5 moves to the position of the PCR plate. A negative pressure is formed in the adsorption cavity 52 by sucking through the vacuum pump 51, and an adsorption force is generated in the adsorption channel 53 to adsorb the PCR below the PCR plate vacuum adsorption plate 5. At the same time, the PCR plate limiting plates 3 prevent the PCR plate from slipping off. Clamping by vacuum adsorption can effectively protect the structure of the PCR plate and prevent the PCR plate from being damaged by hard extrusion when being clamped.
[0019] A plurality of adsorption channels 53 are provided, and the plurality of adsorption channels 53 are arranged at equal intervals along the Y-axis direction inside the PCR plate vacuum adsorption plate 5. The PCR plate vacuum adsorption plate 5 is integrally formed with the adsorption cavity 52 and the adsorption channels 53. The adsorption cavity 52 and the adsorption channels 53 are kept in airtight connection. The multiple adsorption channels 53 can improve the adsorption force and prevent the clamped PCR plate from falling off due to unstable clamping.
[0020] The rotation driving assembly 2 includes a rotation driving device 21 and a bearing 22. The power output end of the rotation driving device 21 is drivingly connected to the rotating seat 1. The bearing 22 is arranged between the rotation driving device 21 and the rotating seat 1. The rotation driving assembly 2 can drive the rotation of the rotating seat 1 to complete the rotational transportation of the PCR plate.
[0021] The PCR plate limiting plate driving assembly 4 includes a hydraulic rod fixing seat 41 disposed within the rotating seat 1, two horizontal hydraulic driving rods 42 respectively disposed on both sides of the hydraulic rod fixing seat 41, and a sliding groove 43 disposed at the bottom of the rotating seat 1. The top of the PCR plate limiting plate 3 passes through the sliding groove 43 and is connected to the horizontal hydraulic driving rod 42 within the rotating seat 1. The PCR plate limiting plate driving assembly 4 drives the PCR plate limiting plate 3 to move, capable of adjusting the distance between the PCR plate limiting plates 3 to adapt to clamping of PCR plates of different sizes. At the same time, using the horizontal hydraulic driving rod 42 as the driving power can effectively maintain the stability of the PCR plate limiting plate 3.
[0022] At one end of the two PCR plate limiting plates 3 close to the PCR plate vacuum adsorption plate 5, rubber pads 31 are respectively provided, which can slow down the collision caused by the PCR plate limiting plate 3 during the process of clamping the PCR plate and prevent damage to the structure of the PCR plate.
[0023] The PCR plate vacuum adsorption plate driving assembly 6 includes a vertical hydraulic driving rod 61 disposed at the bottom of the rotating seat 1. One end of the vertical hydraulic driving rod 61 is fixedly connected to the bottom of the rotating seat 1, and the other end of the vertical hydraulic driving rod 61 is drivingly connected to the PCR plate vacuum adsorption plate 5. The PCR plate vacuum adsorption plate driving assembly 6 can drive the PCR plate vacuum adsorption plate 5 to move in the vertical direction. After the PCR plate vacuum adsorption plate 5 adsorbs the PCR plate, it can clamp the PCR plate to complete the transportation in the vertical direction.
[0024] There are at least two vertical hydraulic driving rods 61, which can improve the stability of driving in the vertical direction and prevent the PCR plate vacuum adsorption plate 5 from tilting during clamping.
[0025] Working principle:
[0026] During operation, the PCR plate limiting plate driving assembly 4 drives the PCR plate limiting plate 3 to move in the horizontal direction, and the PCR plate vacuum adsorption plate driving assembly 6 drives the PCR plate vacuum adsorption plate 5 to move in the vertical direction. The PCR plate limiting plate 3 is adjusted to the width or length of the PCR plate through the PCR plate limiting plate driving assembly 4. The PCR plate vacuum adsorption plate 5 moves to the position of the PCR plate. A negative pressure is formed in the adsorption cavity 52 by pumping through the vacuum pump 51, and the adsorption channel 53 generates an adsorption force to adsorb the PCR below the PCR plate vacuum adsorption plate 5. At the same time, the PCR plate limiting plate 3 prevents the PCR plate from slipping off. Clamping through vacuum adsorption can effectively protect the structure of the PCR plate and prevent the PCR plate from being damaged by hard extrusion when being clamped.
[0027] Certainly, the above description is only a preferred embodiment of the present invention. Therefore, all equivalent changes or modifications made according to the structures, features, and principles described in the scope of the patent application of the present invention are included in the scope of the patent application of the present invention.
Claims
1. A clamping mechanism for a PCR plate, characterized in that: It includes a rotating seat (1), a rotating drive assembly (2) for driving the rotation of the rotating seat (1), two PCR plate limit plates (3) movably arranged horizontally below the rotating seat (1), a PCR plate limit plate drive assembly (4) arranged inside the rotating seat (1) for driving the two PCR plate limit plates (3) to move horizontally, a PCR plate vacuum adsorption plate (5) movably arranged vertically at the bottom of the rotating seat (1), and a PCR plate vacuum adsorption plate drive assembly (6) arranged at the bottom of the rotating seat (1) for driving the PCR plate vacuum adsorption plate (5) to move vertically. The rotating drive assembly (2) is drivingly connected to the rotating seat (1), the PCR plate limit plate drive assembly (4) is drivingly connected to the PCR plate limit plate (3), and the PCR plate vacuum adsorption plate drive assembly (6) is drivingly connected to the PCR plate vacuum adsorption plate (5). A vacuum pump (51) is arranged on the PCR plate vacuum adsorption plate (5), and an adsorption cavity (52) and an adsorption channel (53) are arranged inside the PCR plate vacuum adsorption plate (5). One end of the adsorption cavity (52) is communicated with the vacuum pump (51), the other end of the adsorption cavity (52) is communicated with one end of the adsorption channel (53), and the other end of the adsorption channel (53) is communicated with the outside.
2. The clamping mechanism of a PCR plate according to claim 1, wherein: A plurality of the adsorption channels (53) are provided, and the plurality of adsorption channels (53) are equidistantly arranged along the Y-axis direction inside the PCR plate vacuum adsorption plate (5).
3. The clamping mechanism of a PCR plate according to claim 2, characterized in that: The PCR plate vacuum adsorption plate (5) is integrally formed with the adsorption cavity (52) and the adsorption channel (53).
4. The clamping mechanism of a PCR plate according to claim 1, characterized in that: The rotating drive assembly (2) includes a rotating drive device (21) and a bearing (22). The power output end of the rotating drive device (21) is drivingly connected to the rotating seat (1), and the bearing (22) is arranged between the rotating drive device (21) and the rotating seat (1).
5. The clamping mechanism of a PCR plate according to claim 1, characterized in that: The PCR plate limit plate drive assembly (4) includes a hydraulic rod fixing seat (41) arranged inside the rotating seat (1), two horizontal hydraulic drive rods (42) respectively arranged on both sides of the hydraulic rod fixing seat (41), and a chute (43) arranged at the bottom of the rotating seat (1). The top of the PCR plate limit plate (3) passes through the chute (43) and is connected to the horizontal hydraulic drive rod (42) inside the rotating seat (1).
6. The clamping mechanism of a PCR plate according to claim 1, characterized in that: Rubber pads (31) are respectively arranged at one ends of the two PCR plate limit plates (3) close to the PCR plate vacuum adsorption plate (5).
7. The clamping mechanism of a PCR plate according to claim 1, characterized in that: The PCR plate vacuum adsorption plate drive assembly (6) includes a vertical hydraulic drive rod (61) arranged at the bottom of the rotating seat (1). One end of the vertical hydraulic drive rod (61) is fixedly connected to the bottom of the rotating seat (1), and the other end of the vertical hydraulic drive rod (61) is drivingly connected to the PCR plate vacuum adsorption plate (5).
8. The clamping mechanism of a PCR plate according to claim 7, wherein: At least two of the vertical hydraulic drive rods (61) are provided.