Experiment clamp

By designing experimental fixtures composed of brackets, bottom plates, fasteners and metal sheets, the problem that existing devices cannot accurately fix the lesions is solved, precise fixation and underwater treatment of the lesion area are achieved, head immersion is avoided, and experimental efficiency and safety are improved.

CN223183646UActive Publication Date: 2025-08-05SHENYANG CHANGJIANGYUAN TECH DEV CO LTD
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Patent Information

Application Number
CN202421717313.4
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-07-19
Publication Date
2025-08-05
Estimated Expiration
2034-07-19

AI Technical Summary

Technical Problem

The existing fixation device of mice cannot accurately fix the lesion, resulting in unstable position of the lesion area during the experiment, unable to undergo underwater treatment and avoiding head immersion.

Method used

Design an experimental fixture, including a bracket, bottom plate, fastener, cover plate and metal sheet. The distance between the bracket and the bottom plate is adjusted through the fastener. The through hole of the metal sheet is used for underwater treatment in the lesion area. The cover plate fixes the experimental subject to avoid head immersion.

Benefits of technology

Accurate fixation of the lesion area is achieved, position deviation caused by swing and head immersion during the experiment, and experimental efficiency and safety are improved.

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Abstract

An experiment clamp comprises at least two supports, a bottom plate, a first fastener, a cover plate, a second fastener and a metal sheet. Each support is provided with a support fixing hole, and the support fixing hole is connected with one end of a first fastener. A bottom plate through hole is formed in the middle of the bottom plate, first bottom plate fixing holes are formed in the periphery of the bottom plate, second bottom plate fixing holes are formed in the periphery of the bottom plate through hole, the first bottom plate fixing holes are connected with the other ends of the first fasteners, and the distance between the support and the bottom plate is adjusted through the first fasteners; cover plate fixing holes are formed in the periphery of the cover plate, the cover plate fixing holes are connected with one end of a second fastener, the other end of the second fastener is connected with a second bottom plate fixing hole, and the distance between the cover plate and the bottom plate is adjusted through the second fastener to fix an experimental object; the metal sheet is arranged below the bottom plate, a metal sheet through hole is formed in the middle of the metal sheet, an experimental part of an experimental object is immersed into water through the metal sheet through hole, metal sheet fixing holes are formed in the periphery of the metal sheet, and the second fastener penetrates through the metal sheet fixing holes to be connected with the bottom plate.
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Description

Technical Field

[0001] The utility model belongs to the field of experimental technology, and in particular relates to an experimental clamp. Background Art

[0002] Currently, laboratory animals play a crucial role in safety, efficacy, and standardization testing in many fields of scientific research. They play a crucial role in vaccine and drug development, surgical practice drills, and the effectiveness testing of medical devices. Mice are the most common laboratory animal. During a series of procedures, the mouse's lesion must be immersed in water with its head kept clear of the water surface. During treatment, pain can cause the mouse's body to sway violently, resulting in deviation from the treated area.

[0003] Most of the mouse experimental fixation devices in the existing technology are used for anesthetic injection and dissection of mice. When in use, first open the sealing plate, insert the mouse into the restraint tube from the end of the restraint tube close to the sealing plate, and leave the tail outside the restraint tube. Slide the sealing plate down, and extend the mouse's tail from the space formed by the outlet and the arc-shaped groove. When the sealing plate slides to the bottom, tighten the clamping bolt, and the mouse is now firmly restrained in the restraint tube.

[0004] The existing fixing device has the following deficiencies:

[0005] (1) When using a restraint tube for fixation, it is impossible to accurately expose the subcutaneous lesion of the mouse outside the restraint tube and keep it in place.

[0006] (2) During the experiment, underwater treatment of the lesion was not possible, and the mouse's head was prevented from touching the water surface. Utility Model Content

[0007] In order to address the deficiencies in the prior art, the purpose of the present invention is to provide an experimental clamp that can accurately fix the lesion of the experimental subject, avoid treatment deviation due to the swaying of the experimental subject's body during the experiment, and avoid immersing the subject's head in water during underwater treatment of the lesion.

[0008] In order to achieve the above-mentioned object, the utility model provides an experimental fixture, comprising at least two brackets, a base plate, a first fastener, a cover plate, a second fastener, and a metal sheet;

[0009] A bracket fixing hole is formed on each of the brackets, and the bracket fixing hole is connected to one end of the first fastener;

[0010] A bottom plate through hole is provided in the middle of the bottom plate, a first bottom plate fixing hole is provided around the bottom plate, and a second bottom plate fixing hole is provided around the bottom plate through hole, the first bottom plate fixing hole is connected to the other end of the first fastener, and the distance between the bracket and the bottom plate is adjusted by the first fastener;

[0011] The cover plate is provided with cover plate fixing holes around its periphery, the cover plate fixing holes are connected to one end of the second fastener, and the other end of the second fastener is connected to the second bottom plate fixing hole, and the distance between the cover plate and the bottom plate is adjusted by the second fastener to fix the experimental object;

[0012] The metal sheet is placed under the bottom plate, a metal sheet through hole is opened in the middle of the metal sheet, the experimental part of the experimental object is immersed in water through the metal sheet through hole, metal sheet fixing holes are opened around the metal sheet, and the second fastener is connected to the bottom plate through the metal sheet fixing holes.

[0013] Furthermore, the first fastening member includes a first fastening screw and a first fastening nut, one end of the first fastening screw is connected to the base plate, and the other end passes through the bracket fixing hole, and the first fastening nuts are respectively assembled on the upper and lower sides of the bracket fixing hole, and the distance between the bracket and the base plate is adjusted by adjusting the first fastening nut.

[0014] Furthermore, the second fastener includes a second fastening screw and a second fastening nut, one end of the second fastening screw is connected to the base plate and the metal sheet, and the other end is connected to the cover plate, and the second fastening nut is configured on the upper surface of the cover plate to adjust the position of the cover plate to fix the experimental object.

[0015] Furthermore, the metal sheet is a steel sheet.

[0016] Furthermore, the diameter of the through hole of the metal sheet is smaller than the diameter of the through hole of the bottom plate.

[0017] Furthermore, the cover plate and the metal sheet have the same size.

[0018] Furthermore, the position of the cover plate fixing hole is the same as the position of the metal sheet fixing hole.

[0019] Furthermore, the support is a transparent glass plate, which is placed on both sides of the experimental equipment.

[0020] Furthermore, the cover plate is a transparent glass plate.

[0021] Furthermore, the bottom plate is a transparent glass plate.

[0022] The experimental fixture of the utility model has the following beneficial effects:

[0023] 1. Ability to precisely place the subject's lesion area underwater;

[0024] 2. High experimental efficiency, avoiding deviations in the positioning accuracy of the lesion area caused by the subject's body swinging during the experiment, thereby artificially adjusting the subject's position repeatedly;

[0025] 3. Avoid the possibility that the subject's head may be immersed in water due to violent body swinging during the experiment;

[0026] Other features and advantages of the present invention will be set forth in the following description, and in part will become apparent from the description, or may be understood by practicing the present invention. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] The accompanying drawings are used to provide a further understanding of the present invention and constitute a part of the specification. Together with the embodiments of the present invention, they are used to explain the present invention and do not constitute a limitation of the present invention. In the accompanying drawings:

[0028] Figure 1 This is a schematic diagram of an explosion of an experimental fixture according to the utility model;

[0029] Figure 2 This is a schematic diagram of an experimental fixture assembly according to the utility model;

[0030] Figure 3 Schematic diagram of a bracket of an experimental fixture according to the utility model;

[0031] Figure 4 Schematic diagram of a bottom plate of an experimental fixture according to the present utility model;

[0032] Figure 5 Schematic diagram of a cover plate of an experimental fixture according to the utility model;

[0033] Figure 6 A schematic diagram of a metal sheet of an experimental fixture according to the present utility model;

[0034] Illustration:

[0035] 1- bracket, 2- base plate, 3- first fastener, 4- cover plate, 5- second fastener, 6- metal sheet. DETAILED DESCRIPTION

[0036] In order to make the technical problems, technical solutions and beneficial effects to be solved by the present invention more clearly understood, the present invention is further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not intended to limit the present invention.

[0037] It should be noted that when an element is referred to as being “fixed on” or “disposed on” another element, it may be directly on the other element or indirectly on the other element. When an element is referred to as being “connected to” another element, it may be directly connected to the other element or indirectly connected to the other element.

[0038] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be understood to indicate or imply relative importance or implicitly specify the number of the technical features indicated. Therefore, a feature specified as "first" or "second" may explicitly or implicitly include one or more of such features. In the description of this utility model, "plurality" means two or more, unless otherwise specifically defined. "Several" means one or more, unless otherwise specifically defined.

[0039] In the description of the present invention, it should be understood that the terms "up", "down", "front", "back", "left", "right", etc., indicating directions or positional relationships, are based on the directions or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific direction, be constructed and operated in a specific direction, and therefore cannot be understood as a limitation on the present invention.

[0040] In the description of this utility model, it should be noted that, unless otherwise expressly specified or limited, the terms "installed," "connected," and "connected" should be understood in a broad sense. For example, they can refer to fixed connections, detachable connections, or integral connections; mechanical connections or electrical connections; direct connections or indirect connections through an intermediate medium; and can refer to internal communication between two components or the interaction between two components. Those skilled in the art will understand the specific meanings of the above terms in this utility model based on specific circumstances.

[0041] Example 1

[0042] Figure 1 Schematic diagram of the explosion of the experimental fixture according to the present invention. Figure 2 This is a schematic diagram of an experimental fixture assembly according to the utility model, as shown in FIG. Figure 1 and Figure 2 As shown, the experimental fixture of the present invention includes two brackets 1, a base plate 2, a first fastener 3, a cover plate 4, a second fastener 5, and a metal sheet 6.

[0043] Two bracket fixing holes are provided on each of the two brackets 1, which are respectively used to cooperate with the first fixing member 3 to adjust the height of the bracket.

[0044] An elliptical through hole is set in the middle of the bottom plate 2 to cooperate with the bracket fixing hole for underwater precision treatment of the mouse lesion area. Four bottom plate fixing holes are set around it to cooperate with the first fastener 3 for fixation.

[0045] Optionally, the first fastener 3 includes a first fastening screw and a first fastening nut, one end of the first fastening screw is fixed to the base plate 2, and the other end passes through the four bracket fixing holes of the bracket 1. A first fastening nut is installed on the upper and lower parts of the bracket to adjust the distance between the fixed bracket 1 and the base plate 2.

[0046] Optionally, the first fastening screw is a hexagon socket screw.

[0047] Alternatively, as Figure 3 As shown, the bracket 1 is two rectangular transparent organic glass plates, which are fixed with the first fastener 3 in conjunction with the fixing holes of the bottom plate. The height can be adjusted up and down and are placed on both sides of the experimental equipment.

[0048] Four cover plate fixing holes are arranged around the cover plate 4 and cooperate with the second fastener 5 to realize the up and down movement of the cover plate 4 to fix the experimental object, such as a mouse.

[0049] Optionally, the second fastening member 5 includes a second fastening screw and a second fastening nut.

[0050] Alternatively, as Figure 5 As shown, the cover plate 4 is a square transparent organic glass plate with the same size as the metal sheet 6. The positions of the through holes around it are the same as those of the metal sheet 6. It is placed above the metal sheet 6 and is used with screws and nuts. It can be adjusted up and down by tightening or loosening the nuts to lock and fix the mouse.

[0051] In this embodiment, one end of the second fastening screw is fixed with the base plate 2 and the through hole of the metal sheet 6, and the other end is matched with the cover plate 4. A second fastening nut is configured on the upper surface of the cover plate 4 to adjust the position of the cover plate and fix and tighten the mouse.

[0052] Optionally, the second fastening screw is a hexagon socket screw.

[0053] A through hole with a diameter of 1.5 cm is set in the middle of the metal sheet 6, so that the mouse lesion area can be immersed in water through the through hole to experiment with underwater precision treatment. Four metal sheet fixing holes are set around it to cooperate with the bottom plate 2 and fixed with a second fastening screw.

[0054] In this embodiment, Figure 6 As shown, the metal sheet 6 is a square metal sheet with a 1.5 cm through hole reserved in the middle and four circular metal sheet fixing holes at the four corners to match the second base plate fixing holes around the elliptical hole on the base plate 2 and fixed with four second fastening screws.

[0055] In this embodiment, the elliptical through hole of the bottom plate 2 is for placing the torso below the head of the mouse, while the through hole on the metal sheet 6 is for placing the experimental subject in the lesion area.

[0056] Alternatively, as Figure 4 As shown, the base plate 2 is a rectangular organic glass plate with an elliptical through hole in the middle. Four circular second base plate fixing holes are reserved around the through hole to cooperate with the metal sheet fixing holes around the metal sheet 6. The four outer corners are fixed with four first fasteners 3 and used in conjunction with the bracket 1.

[0057] In this embodiment, the metal material of the metal sheet 6 can prevent the heat generated during the experiment or treatment from causing thermal damage to the experimental subject. The organic glass plate of the bracket 1, the base plate 2, and the cover plate 4 can facilitate observation of the reaction of the experimental subject during the experiment or treatment, and stop or change the experimental operation in time to avoid harming the experimental subject.

[0058] In this embodiment, mice are used as experimental subjects. During the experiment, the mouse fixing bracket is first placed above the water tank of the beam wave knife bed, and the bottom plate is made to contact the water surface by adjusting the hexagonal screw. Then, the anesthetized mouse is placed on the bottom plate, and the lesion area is aligned with the center hole of the metal sheet, and the lesion area is placed underwater. Then, the cover plate is installed and adjusted to the appropriate position, and the mouse is fixed by tightening the nut.

[0059] The utility model provides an experimental fixation device, and the experimental subjects include but are not limited to mice. The purpose is to reduce the experimental difficulty in the fixation process, speed up work efficiency, limit the range of activity of mice, prevent the mice from shaking violently and causing the treatment area to deviate from the calibration position, and during the experiment, the lesion area can be immersed in water while preventing other parts of the mice from contacting the water surface, thereby preventing the mice from drowning.

[0060] Those skilled in the art will understand that the above description is merely a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art will be able to modify the technical solutions described in the aforementioned embodiments or replace some of the technical features therein with equivalents. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principles of the present invention shall be included within the scope of protection of the present invention.

Claims

1. An experimental fixture, characterized in that: It includes at least two brackets, a bottom plate, a first fastener, a cover plate, a second fastener, and a metal sheet; A bracket fixing hole is formed on each of the brackets, and the bracket fixing hole is connected to one end of the first fastener; A bottom plate through hole is provided in the middle of the bottom plate, a first bottom plate fixing hole is provided around the bottom plate, and a second bottom plate fixing hole is provided around the bottom plate through hole, the first bottom plate fixing hole is connected to the other end of the first fastener, and the distance between the bracket and the bottom plate is adjusted by the first fastener; The cover plate is provided with cover plate fixing holes around its periphery, the cover plate fixing holes are connected to one end of the second fastener, and the other end of the second fastener is connected to the second bottom plate fixing hole, and the distance between the cover plate and the bottom plate is adjusted by the second fastener to fix the experimental object; The metal sheet is placed under the bottom plate, a metal sheet through hole is opened in the middle of the metal sheet, the experimental part of the experimental object is immersed in water through the metal sheet through hole, metal sheet fixing holes are opened around the metal sheet, and the second fastener is connected to the bottom plate through the metal sheet fixing holes.

2. The experimental fixture according to claim 1, characterized in that: The first fastening member includes a first fastening screw and a first fastening nut. One end of the first fastening screw is connected to the base plate, and the other end passes through the bracket fixing hole. The first fastening nuts are respectively assembled on the upper and lower sides of the bracket fixing hole. The distance between the bracket and the base plate is adjusted by adjusting the first fastening nut.

3. The experimental fixture according to claim 1, characterized in that: The second fastener includes a second fastening screw and a second fastening nut. One end of the second fastening screw is connected to the base plate and the metal sheet, and the other end is connected to the cover plate. A second fastening nut is configured on the upper surface of the cover plate to adjust the position of the cover plate to fix the experimental object.

4. The experimental fixture according to claim 1, characterized in that: The metal sheet is a steel sheet.

5. The experimental fixture according to claim 1 or 4, characterized in that: The diameter of the metal sheet through hole is smaller than the diameter of the bottom plate through hole.

6. The experimental fixture according to claim 1, characterized in that: The cover plate and the metal sheet have the same size.

7. The experimental fixture according to claim 1 or 6, characterized in that: The position of the cover plate fixing hole is the same as the position of the metal sheet fixing hole.

8. The experimental fixture according to claim 1, characterized in that: The bracket is a transparent glass plate and is placed on both sides of the experimental equipment.

9. The experimental fixture according to claim 1, characterized in that: The cover plate is a transparent glass plate.

10. The experimental fixture according to claim 1, characterized in that: The bottom plate is a transparent glass plate.