Blending device and quality control auxiliary equipment

Abstract

The utility model discloses a uniform mixing device and quality control auxiliary equipment. A driving part of the uniform mixing device is arranged on a base; the transmission part is arranged on the base and is connected with the driving part; the loading mechanism is connected with the transmission part, and the loading mechanism is used for placing a quality control material to be uniformly mixed; the driving part is used for driving the transmission part to rotate, and the transmission part is used for driving the loading mechanism to rotate so as to uniformly mix the quality control material. Through the mode, the uniform mixing device can drive the loading mechanism to rotate through the driving part, so that the quality control materials in the loading mechanism are uniformly mixed in the rotating process, and the automatic uniform mixing of the quality control materials is realized; the uniform mixing device can uniformly mix a plurality of quality control substances through uniform mixing operation, so that the normalization of the uniform mixing operation is improved, the accidents of quality control result deviation, cell disruption, quality control scrapping and the like caused by non-standard manual operation are reduced, the quality control cost is reduced, and the detection efficiency of a sample is improved.

Description

Technical Field

[0001] The present application relates to the field of medical device technology, and in particular to a mixing device and quality control auxiliary equipment. Background Art

[0002] Existing sample analyzers require quality control using control materials before and at regular intervals during testing to ensure that the instrument's quality meets standards. Relevant testing management standards (such as ISO 15189) also stipulate that in vitro diagnostic equipment must undergo quality control at least once daily, at no fewer than two levels.

[0003] However, existing sample analyzers rely heavily on manual intervention during quality control operations. Workers must manually mix the quality control samples before loading them onto the analyzer for testing, which is susceptible to operator error. Improper mixing can lead to deviations in quality control results, cell breakage, and scrapped samples, increasing the number of retests and quality control costs, ultimately reducing sample testing efficiency. Utility Model Content

[0004] In order to solve the above problems existing in the prior art, the present application provides a mixing device and quality control auxiliary equipment.

[0005] In order to solve the technical problems existing in the prior art, the present application provides a first technical solution: providing a mixing device, which is applied to the quality control material of the sample analyzer, and the above-mentioned mixing device includes a base, a driving member, a transmission member and a loading mechanism; the above-mentioned driving member is arranged on the above-mentioned base; the above-mentioned transmission member is arranged on the above-mentioned base and connected to the above-mentioned driving member; the above-mentioned loading mechanism is connected to the above-mentioned transmission member, and the above-mentioned loading mechanism is used to place the quality control material to be mixed; wherein, the above-mentioned driving member is used to drive the above-mentioned transmission member to rotate, and the above-mentioned transmission member is used to drive the above-mentioned loading mechanism to rotate to mix the above-mentioned quality control material.

[0006] Optionally, the loading mechanism includes a loading seat and a limiting member, the loading seat is connected to the transmission member, the limiting member is arranged on the loading seat, the loading seat is formed with at least one accommodating cavity, and the limiting member is used to relatively fix the quality control object in the accommodating cavity.

[0007] Optionally, the above-mentioned limiting member includes a fixing member and an elastic member, one end of the above-mentioned elastic member is fixed to the side wall of the above-mentioned loading seat through the above-mentioned fixing member, and the other end of the above-mentioned elastic member abuts against the above-mentioned quality control object through the above-mentioned accommodating cavity to limit the relative movement of the above-mentioned quality control object in the above-mentioned accommodating cavity.

[0008] Optionally, the mixing device further comprises a rotating shaft, and the transmission member is connected to the base via the rotating shaft, and the transmission member is configured to rotate along the rotating shaft under the drive of the driving member, and drive the loading mechanism to rotate along the central axis of the rotating shaft.

[0009] Optionally, the loading mechanism includes a first position and a second position, the loading mechanism is located at the first position, the extension direction of the tube body of the quality control object is parallel to the direction of gravity, and the driving member is used to drive the loading mechanism in the first position to rotate in a clockwise direction or counterclockwise direction so that the loading mechanism is located at the second position.

[0010] Optionally, during the process of the loading mechanism rotating from the first position to the second position, the rotation range of the loading mechanism is between 25° and 140°.

[0011] Optionally, the transmission member includes a first transmission wheel and a second transmission wheel, the first transmission wheel is fixed on the output shaft of the driving member, the second transmission wheel is fixed on the rotating shaft and the loading mechanism is connected to the second transmission wheel, and the gears of the first transmission wheel and the second transmission wheel are engaged with each other.

[0012] Optionally, the number of teeth of the first transmission wheel is smaller than the number of teeth of the second transmission wheel, and / or the diameter of the first transmission wheel is smaller than the diameter of the second transmission wheel.

[0013] Optionally, the mixing device includes a detection mechanism, which is disposed on the base and opposite to the loading mechanism, and is used to detect a rotation angle of the loading mechanism.

[0014] In order to solve the technical problems existing in the prior art, the present application provides a second technical solution: providing a quality control auxiliary equipment, including any mixing device as described above.

[0015] Compared with the prior art, the mixing device of the present application includes a base, a driving member, a transmission member and a loading mechanism; the driving member is arranged on the base; the transmission member is arranged on the base and connected to the driving member; the loading mechanism is connected to the transmission member, and the loading mechanism is used to place the quality control material to be mixed; wherein the driving member is used to drive the transmission member to rotate, so as to drive the loading mechanism to rotate along the central axis through the transmission member and mix the quality control material. Through the above manner, the mixing device of the present application can drive the rotation of the loading mechanism through the driving member, so that the quality control material in the loading mechanism is mixed during the rotation process, thereby realizing automatic mixing of the quality control material; and the mixing device can mix multiple quality control materials through a unified mixing operation, thereby improving the standardization of the mixing operation, reducing accidents such as deviation of quality control results, cell breakage, and quality control scrapping due to non-standard manual operation, reducing quality control costs, and improving sample detection efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the following briefly introduces the drawings required for use in the embodiments. Obviously, the drawings described below are only some embodiments of the present application. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work.

[0017] Figure 1 1 is a schematic structural diagram of a first embodiment of a mixing device provided in this application;

[0018] Figure 2 is a structural schematic diagram of a second embodiment of the mixing device provided by the present application;

[0019] Figure 3 It is a structural schematic diagram of the third embodiment of the mixing device provided in this application.

[0020] In the figure, 1. mixing device; 10. base; 20. driving member; 30. transmission member; 310. first transmission wheel; 320. second transmission wheel; 40. loading mechanism; 410. loading seat; 420. limiting member; 421. fixing member; 422. elastic member; 50. rotating shaft; 60. detection mechanism; 70. quality control object. DETAILED DESCRIPTION

[0021] The present application will be further described in detail below in conjunction with the accompanying drawings and examples. It is particularly noted that the following examples are only intended to illustrate the present application and are not intended to limit the scope of the present application. Similarly, the following examples are only some examples of the present application and not all examples. All other examples obtained by those of ordinary skill in the art without creative work are intended to fall within the scope of protection of this application.

[0022] References to "embodiments" herein mean that a particular feature, structure, or characteristic described in connection with the embodiments may be included in at least one embodiment of the present application. The appearance of the phrase in various places in the specification does not necessarily refer to the same embodiment, nor does it constitute an independent or alternative embodiment that is mutually exclusive of other embodiments. It is understood, both explicitly and implicitly, by those skilled in the art that the embodiments described herein may be combined with other embodiments.

[0023] In the description of this application, it should be noted that, unless otherwise clearly specified and limited, the terms "install", "set", "connect", and "connect" should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or a connection through an intermediate medium. For ordinary technicians in this field, if there are directional indications (such as up, down, left, right, front, back...) involved in the embodiments of this application, the directional indications are only used to explain the relative position relationship, movement status, etc. between the components under a certain specific posture (as shown in the accompanying drawings). If the specific posture changes, the directional indications will also change accordingly.

[0024] See Figure 1-3 , Figure 1 is a structural diagram of the first embodiment of the mixing device provided in this application, Figure 2 is a structural diagram of the second embodiment of the mixing device provided by this application, Figure 3 Schematic diagram of the structure of the third embodiment of the mixing device provided by this application. Figure 1-3 As shown, the mixing device 1 of this embodiment is applied to the quality control material 70 of the sample analyzer. The mixing device 1 is used to mix the quality control material 70 so that the mixed quality control material 70 can be used for quality control testing of the sample analyzer and realize calibration of the sample analyzer.

[0025] Specifically, the mixing device 1 includes a base 10, a driving member 20, a transmission member 30, and a loading mechanism 40. The driving member 20 is disposed on the base 10; the transmission member 30 is disposed on the base 10 and connected to the driving member 20; the loading mechanism 40 is connected to the transmission member 30 and is used to place the quality control material 70 to be mixed. The driving member 20 is used to drive the transmission member 30 to rotate, and the transmission member 30 is used to drive the loading mechanism 40 to rotate to mix the quality control material 70.

[0026] The driving member 20 includes, but is not limited to, components capable of outputting driving force, such as a motor and an electric cylinder. The transmission member 30 may transmit the driving force of the driving member 20 to the loading mechanism 40 via, but is not limited to, a gear drive, a worm gear drive, a belt drive, and a chain drive, so as to rotate the loading mechanism 40 along the central axis. In a possible embodiment, the rotating shaft 50 of the transfer mechanism is disposed on the base 10, and the rotating shaft 50 may be located on the central axis of the transfer mechanism to enable rotation along the central axis, or the rotating shaft 50 may be located on a side of the transfer mechanism that deviates from the central axis to enable eccentric rotation of the transfer mechanism.

[0027] Furthermore, the loading mechanism 40 may be provided with at least one mixing position for mixing at least one quality control material 70. For example, the loading mechanism 40 includes a loading seat 410, and a first accommodating cavity and a second accommodating cavity provided in the loading seat 410. The first accommodating cavity and the second accommodating cavity are respectively used to place test tubes of different quality control materials 70, so as to achieve simultaneous mixing of multiple quality control materials 70 and improve mixing efficiency.

[0028] In the embodiment of the present application, the mixing device 1 can drive the rotation of the loading mechanism 40 through the driving member 20, so that the quality control material 70 in the loading mechanism 40 is mixed during the rotation process, thereby realizing automatic mixing of the quality control material 70; and the mixing device 1 can mix multiple quality control materials 70 through a unified mixing operation, thereby improving the standardization of the mixing operation, reducing accidents such as deviation of quality control results, cell breakage, and quality control scrapping caused by non-standard manual operation, reducing quality control costs, and improving sample detection efficiency.

[0029] In one embodiment, the loading mechanism 40 includes a loading seat 410 and a limiting member 420. The loading seat 410 is connected to the transmission member 30. The limiting member 420 is arranged on the loading seat 410. The loading seat 410 is formed with at least one accommodating cavity. The limiting member 420 is used to relatively fix the quality control object 70 in the accommodating cavity.

[0030] Specifically, the loading base 410 can be mounted on the base 10 via the transmission member 30. The loading base 410 is fixed relative to the transmission member 30 via screws, bolts, and other components, so that the transmission member 30 drives the loading base 410 to rotate. The loading base 410 is formed with at least one accommodating cavity, each of which has dimensions corresponding to the test tube size of the quality control object 70. A stopper 420 is disposed on the loading base 410 and is used to relatively fix the quality control object 70 within the accommodating cavity, thereby confining the quality control object 70 within the accommodating cavity during rotation of the loading mechanism 40.

[0031] In one embodiment, the stopper 420 may be disposed on a side of the loading base 410 away from the transmission member 30. An opening may be provided on a side of the loading base 410 near the stopper 420, the opening being in communication with the accommodating chamber. The stopper 420 may abut against the wall of the test tube of the quality control object 70 in the accommodating chamber through the opening to limit the relative movement of the quality control object 70 within the accommodating chamber. In another embodiment, a through hole may be provided on the inner wall of the accommodating chamber of the loading base 410, the stopper 420 may be disposed within the through hole. The stopper 420 may elastically protrude relative to the inner wall of the accommodating chamber and abut against the quality control object 70 to limit the relative movement of the quality control object 70 within the accommodating chamber.

[0032] In the above manner, the mixing device 1 of this embodiment is connected to the transmission member 30 through the loading seat 410, and the limiting member 420 is arranged on the loading seat 410. The loading seat 410 is formed with at least one accommodating cavity. The limiting member 420 is used to relatively fix the quality control object 70 in the accommodating cavity, so that the quality control object 70 can be confined in the accommodating cavity during the rotation of the loading mechanism 40, reducing or avoiding accidents such as the quality control object 70 falling or breaking during the rotation process, thereby improving the reliability of the mixing device 1.

[0033] Optionally, the limiting member 420 includes a fixing member 421 and an elastic member 422, one end of the elastic member 422 is fixed to the side wall of the loading seat 410 through the fixing member 421, and the other end of the elastic member 422 abuts against the quality control object 70 through the accommodating cavity to limit the relative movement of the quality control object 70 in the accommodating cavity.

[0034] Specifically, an opening is provided on one side of the loading seat 410 near the limiting member 420, which is in communication with the accommodating chamber. One end of the elastic member 422 can be fixed to the side wall of the loading seat 410 near the opening via a fixing member 421. The other end of the elastic member 422 corresponds to the hollowed-out portion of the opening. When the quality control object 70 is placed in the accommodating chamber, the other end of the elastic member 422 can abut against the quality control object 70 through the opening, thereby pressing the quality control object 70 into the accommodating chamber through elastic force and limiting the relative movement of the quality control object 70 within the accommodating chamber. The fixing member 421 includes but is not limited to fasteners such as bolts, screws, and rivets, and the elastic member 422 includes but is not limited to abutting structures connected by shrapnel or springs.

[0035] In this embodiment, one end of the elastic member 422 of the mixing device 1 is fixed to the side wall of the loading seat 410 through the fixing member 421, and the other end of the elastic member 422 abuts against the quality control object 70 through the accommodating cavity to limit the relative movement of the quality control object 70 in the accommodating cavity, so that the quality control object 70 can be confined in the accommodating cavity during the rotation of the loading mechanism 40, reducing or avoiding accidents such as the quality control object 70 falling or breaking during the rotation process; and the setting structure of the elastic member 422 is simple and easy to use.

[0036] In one embodiment, the mixing device 1 further includes a rotating shaft 50 , and the transmission member 30 is connected to the base 10 via the rotating shaft 50 . The transmission member 30 is used to rotate along the rotating shaft 50 under the drive of the driving member 20 , and drive the loading mechanism 40 to rotate along the central axis of the rotating shaft 50 .

[0037] Specifically, the transmission member 30 is fixed to the base 10 via the rotating shaft 50 and is connected to the output shaft of the driving member 20. When the driving member 20 is in operation, the output shaft of the driving member 20 outputs driving force to the transmission member 30, so that the transmission member 30 drives the loading mechanism 40 to rotate along the central axis of the rotating shaft 50 under the action of the driving force. In this manner, the mixing device 1 of this embodiment can mix the quality control materials 70 within the loading mechanism 40 during rotation, achieving automatic mixing of the quality control materials 70. Moreover, the mixing device 1 can mix multiple quality control materials 70 through a unified mixing operation, improving the standardization of the mixing operation.

[0038] Optionally, the loading mechanism 40 includes a first position and a second position. The loading mechanism 40 is located in the first position, and the extension direction of the tube body of the quality control object 70 is parallel to the direction of gravity. The driving member 20 is used to drive the loading mechanism 40 in the first position to rotate in a clockwise direction or counterclockwise direction so that the loading mechanism 40 is located in the second position.

[0039] Specifically, the loading mechanism 40 can switch back and forth between a first position and a second position during the rotation process. The first position is the initial position of the loading mechanism 40. When the loading mechanism 40 is in the first position, the extension direction of the tube body of the quality control object 70 is parallel to the direction of gravity; the second position is the maximum deflection position of the loading mechanism 40, that is, the position where the deflection angle of the loading mechanism 40 relative to the first position is the largest during the rotation process. The driving member 20 is used to drive the loading mechanism 40 in the first position to rotate in a clockwise or counterclockwise direction so that the loading mechanism 40 is in the second position. Among them, the driving member 20 can drive the loading mechanism 40 to rotate 360° in a clockwise or counterclockwise direction to achieve rotation at any angle and speed according to the requirements of mixing the quality control object 70.

[0040] In a possible embodiment, the driving member 20 includes a motor, the loading mechanism 40 is in the first position, and the driving member 20 is in the motor's initial position. The driving member 20 is configured to rotate forward or reverse in the initial position to rotate the loading mechanism 40 clockwise or counterclockwise from the first position to the second position. For example, the maximum deflection position of the loading mechanism 40 can be controlled by defining the number of rotation steps corresponding to the motor in the second position and subsequently controlling the number of rotation steps of the driving member 20 in the initial position. This control method is simple and easy to implement, effectively reducing the structural complexity of the mixing device 1.

[0041] Furthermore, when the loading mechanism 40 rotates from the first position to the second position, the rotation range of the loading mechanism 40 is between 25° and 140°.

[0042] Specifically, when the loading mechanism 40 rotates from the first position to the second position in a clockwise or counterclockwise direction, the rotation range of the loading mechanism 40 is between 25° and 140°. For example, the rotation angle between the first position and the second position can be 25°, 30°, 35°, 40°, 45°, 55°, 60°, 65°, 70°, 75°, 80°, 85°, 90°, 95°, 100°, 105°, 110°, 115°, 120°, 125°, 130°, 135° or 140°. In this embodiment, the rotation angle of the loading mechanism 40 when rotating from the initial first position to the second position is between 25° and 140°, so that the quality control material 70 can achieve uniform distribution of particles during the rotation process and reduce the problem of deviation of quality control results due to excessive or insufficient mixing.

[0043] The mixing device 1 may further include a control circuit, which is connected to the driving member 20 and is used to control the rotation of the driving member 20. In a possible embodiment, the control circuit can control the speed and rotation position of the motor by inputting the number of pulses and pulse speed of the driving member 20, so that the loading mechanism 40 can swing between preset positions along a preset speed. For example, when the loading mechanism 40 is in the first position, the control circuit can control the loading mechanism 40 to rotate to the following positions through the driving member 20: 30° counterclockwise rotation, 135° clockwise rotation, 135° counterclockwise rotation, 135° clockwise rotation, ...; the above-mentioned 135° clockwise and 135° counterclockwise rotation can be defined as one cycle, and 135° is cycled 50 times, and the interval of each motor reversal is set to 0.7s. Through the above-mentioned example method, the loading mechanism 40 can simulate the manual mixing method to mix the quality control material 70, and the mixed quality control material 70 can be tested on the machine with a uniform mixing degree when applied to the quality control test of the sample analyzer, thereby improving the standardization of the mixing operation, reducing accidents such as deviation of quality control results, cell breakage, and quality control scrapping caused by non-standard manual operation, reducing quality control costs, and improving sample detection efficiency.

[0044] Optionally, the transmission member 30 includes a first transmission wheel 310 and a second transmission wheel 320, the first transmission wheel 310 is fixed on the output shaft of the driving member 20, the second transmission wheel 320 is fixed on the rotating shaft 50 and the loading mechanism 40 is connected to the second transmission wheel 320, and the gears of the first transmission wheel 310 and the second transmission wheel 320 are engaged with each other.

[0045] Specifically, the transmission member 30 can transmit the driving force of the driving member 20 to the loading mechanism 40 through gear transmission. The transmission ratio of the first transmission wheel 310 and the second transmission wheel 320 is accurate and stable, with high transmission efficiency, which can effectively improve the reliability of the loading mechanism 40 during rotation. According to the rotation requirements of the loading mechanism 40, the gears of the first transmission wheel 310 and the second transmission wheel 320 can be configured as internal gears or external gears. For example, the external gears of the first transmission wheel 310 and the second transmission wheel 320 are meshed with each other, or the internal gear of the first transmission wheel 310 and the external gear of the second transmission wheel 320 are meshed with each other, or the external gear of the first transmission wheel 310 and the internal gear of the second transmission wheel 320 are meshed with each other.

[0046] Furthermore, the number of teeth of the first transmission wheel 310 is smaller than the number of teeth of the second transmission wheel 320 , and / or the diameter of the first transmission wheel 310 is smaller than the diameter of the second transmission wheel 320 .

[0047] Specifically, the first transmission wheel 310 serves as a driving wheel and the second transmission wheel 320 serves as a driven wheel. The number of teeth and / or the diameter of the first transmission wheel 310 are smaller than those of the second transmission wheel 320, so that the transmission ratio between the first transmission wheel 310 and the second transmission wheel 320 is less than 1. The rotation speed of the first transmission wheel 310 is slower than that of the second transmission wheel 320, thereby achieving a deceleration effect during the transmission process, thereby increasing the output torque of the driving member 20 and improving the rotation efficiency of the loading mechanism 40.

[0048] In one embodiment, the mixing device 1 includes a detection mechanism 60 . The detection mechanism 60 is disposed on the base 10 and is opposite to the loading mechanism 40 . The detection mechanism 60 is used to detect the rotation angle of the loading mechanism 40 .

[0049] Specifically, the detection mechanism 60 of the mixing device 1 includes but is not limited to a position sensor, an optical coupler detection sensor, etc. The detection mechanism 60 is opposite to the loading mechanism 40 and is used to detect the rotation angle of the loading mechanism 40, so as to facilitate the subsequent adjustment of the rotation angle, mixing mode, etc. of the loading mechanism 40. In a possible embodiment, the loading mechanism 40 is defined with an initial first position and a second position of maximum deflection. The detection mechanism 60 can be used to detect whether the loading mechanism 40 is in the first position. For example, by setting an optical coupler detection sensor at a position corresponding to the bottom of the loading mechanism 40 on the base 10, the loading mechanism 40 blocks the optical coupler detection sensor when it is in the first position, and then the control circuit locates the loading mechanism 40 in the first position through the information of the optical coupler detection sensor, so as to facilitate the subsequent control of the maximum deflection position of the loading mechanism 40 by controlling the number of rotation steps of the driving member 20 in the initial position. The structure is simple and easy to implement, which can effectively reduce the manufacturing cost of the mixing device 1.

[0050] The present application also provides a quality control auxiliary device for use in the pre-processing of a quality control material 70 in a sample analyzer, enabling the processed quality control material 70 to be used for on-board testing by the sample analyzer. The quality control auxiliary device includes a mixing device 1 as described in any of the above embodiments, for mixing the quality control material 70.

[0051] Optionally, the quality control auxiliary equipment may further include a rewarming module connected to the mixing device 1. The quality control material 70 can usually be stored in a refrigerated environment. After the quality control material 70 is obtained, the rewarming module is used to rewarm the quality control material 70 to bring it to a preset temperature. The mixing device 1 is used to mix the rewarmed quality control material 70 so that the mixed quality control material 70 can be directly used for on-machine testing.

[0052] Optionally, the quality control auxiliary device may further include a scheduling module, which is connected to the rewarming module and the mixing device 1, respectively, and is used to move the rewarmed quality control material 70 in the rewarming module to the mixing device 1 for mixing. Furthermore, the quality control auxiliary device may further include a storage module connected to the scheduling module, the storage module is used to store the quality control material 70 in a refrigerated environment, and the scheduling module is used to move the quality control material 70 in the storage module to the rewarming module.

[0053] Through the above-described approach, the quality control auxiliary device of this embodiment can assist personnel in performing at least one of the following operations: automated sampling, rewarming, and mixing, thereby reducing manual workload. Furthermore, when the quality control auxiliary device is used in an assembly line testing workshop comprised of multiple sample analyzers, it can effectively reduce or eliminate manual repetitive quality control operations, thereby lowering labor costs and improving quality control efficiency.

[0054] The effects of the present application are described below by way of examples.

[0055] Example 1:

[0056] A first group of quality control materials and a second group of quality control materials having the same concentration and composition are defined. The first group of quality control materials are shaken samples obtained by a staff member performing a standard mixing method on a low-value quality control sample at a first concentration. The second group of quality control materials are samples obtained by mixing the low-value quality control sample at a first concentration using a mixing device in any of the above embodiments. The first group of quality control materials and the second group of quality control materials are respectively input into the same sample analyzer for quality control operations under different analysis modes to obtain the test results shown in Table 1.

[0057] Table 1: Differences in test results of low-value quality control materials under manual mixing and mechanical mixing

[0058] Analysis Mode Red blood cells leukocyte platelets Hematocrit mean corpuscular volume platelets Group 1 3.91 2.25 58 18.4 81.8 71 Group 2 3.96 2.34 59 19.1 81.8 68 Standard range 3.0％ 2.0％ 2.0％ 2.0％ 1.0％ 8.0％ in conclusion PASS PASS PASS PASS PASS PASS

[0059] The differences in the results of the first set of quality control materials and the second set of quality control materials in the analysis modes of red blood cells, white blood cells, platelets, hematocrit, mean hematocrit, and platelets in this embodiment are all within the standard range.

[0060] Example 2:

[0061] A third set of quality control materials and a fourth set of quality control materials having the same concentration and composition are defined. The third set of quality control materials are shaken samples obtained by a worker performing a standard mixing method on a median quality control sample at a second concentration. The fourth set of quality control materials are samples obtained by mixing the median quality control sample at the second concentration using a mixing device according to any of the above embodiments. The second concentration is greater than the first concentration. The third and fourth sets of quality control materials are respectively input into the same sample analyzer and subjected to quality control operations under different analysis modes to obtain the test results shown in Table 2.

[0062] Table 2: Differences in test results of median quality control materials under manual mixing and mechanical mixing

[0063] Analysis Mode Red blood cells leukocyte platelets Hematocrit mean corpuscular volume platelets Group 3 7.26 4.62 135 42.4 91.8 286 Group 4 7.28 4.61 132 42.3 91.8 293 Standard range 2.5％ 1.5％ 1.0％ 1.5％ 1.0％ 4.0％ in conclusion PASS PASS PASS PASS PASS PASS

[0064] The differences in the results of the third and fourth sets of quality control materials in the analysis modes of red blood cells, white blood cells, platelets, hematocrit, mean hematocrit, and platelets in this embodiment are all within the standard range.

[0065] Example 3:

[0066] Table 3: Differences in test results of high-value quality control materials under manual mixing and mechanical mixing

[0067]

[0068]

[0069] A fifth and sixth set of quality control materials having the same concentration and composition are defined. The fifth set of quality control materials is a shaken sample obtained by a worker performing a standard mixing method on a high-value quality control sample at a third concentration. The sixth set of quality control materials is a sample obtained by mixing a high-value quality control sample at a third concentration using a mixing device according to any of the above embodiments. The third concentration is greater than the second concentration. The fifth and sixth sets of quality control materials are respectively input into the same sample analyzer and subjected to quality control operations under different analysis modes to obtain the test results shown in Table 3.

[0070] The differences in the results of the fifth and sixth sets of quality control materials in the analysis modes of red blood cells, white blood cells, platelets, hematocrit, mean hematocrit, and platelets were all within the standard range.

[0071] It can be seen from the above results that, whether it is a low-value quality control material, a medium-value quality control material or a high-value quality control material, the difference in results between the quality control material obtained by manual mixing and the quality control material obtained by the above-mentioned mixing device under different analysis modes is within the standard range. There is no significant difference between the mechanical mixing of the quality control material by the above-mentioned mixing device and the standard manual mixing method. The mixing device of the embodiment of the present application can perform uniform mixing of multiple quality control materials under the premise of simulating manual mixing, ensure that the mixing degree of the quality control materials is within the same standard range, improve the standardization of the mixing operation, reduce the quality control result deviation, cell breakage, quality control scrapping and other accidents caused by non-standard manual operation, reduce quality control costs, and improve sample detection efficiency.

[0072] The above description is only an implementation method of the present application and does not limit the patent scope of the present application. Any equivalent structure or equivalent process transformation made using the contents of the description and drawings of this application, or directly or indirectly applied in other related technical fields, are also included in the patent protection scope of the present application.

Claims

1. A mixing device, characterized in that: The quality control material used in the sample analyzer, the mixing device includes: base; A driving member, disposed on the base; A transmission member, disposed on the base and connected to the driving member; A loading mechanism connected to the transmission member, the loading mechanism being used to place the quality control material to be mixed; The driving member is used to drive the transmission member to rotate, and the transmission member is used to drive the loading mechanism to rotate to mix the quality control material.

2. The mixing device according to claim 1, characterized in that The loading mechanism includes a loading seat and a limiting member, the loading seat is connected to the transmission member, the limiting member is arranged on the loading seat, the loading seat is formed with at least one accommodating cavity, and the limiting member is used to relatively fix the quality control object in the accommodating cavity.

3. The mixing device according to claim 2, characterized in that: The limiting member includes a fixing member and an elastic member, one end of the elastic member is fixed to the side wall of the loading seat through the fixing member, and the other end of the elastic member abuts against the quality control object through the accommodating cavity to limit the relative movement of the quality control object in the accommodating cavity.

4. The mixing device according to claim 1, characterized in that The mixing device further includes a rotating shaft, and the transmission member is connected to the base via the rotating shaft. The transmission member is configured to rotate along the rotating shaft under the drive of the driving member, and drive the loading mechanism to rotate along the central axis of the rotating shaft.

5. The mixing device according to claim 4, characterized in that: The loading mechanism includes a first position and a second position. The loading mechanism is located in the first position, and the extension direction of the tube body of the quality control object is parallel to the direction of gravity. The driving member is used to drive the loading mechanism in the first position to rotate in a clockwise direction or a counterclockwise direction so that the loading mechanism is located in the second position.

6. The mixing device according to claim 5, characterized in that: During the process of the loading mechanism rotating from the first position to the second position, the rotation range of the loading mechanism is between 25° and 140°.

7. The mixing device according to claim 4, characterized in that: The transmission member includes a first transmission wheel and a second transmission wheel. The first transmission wheel is fixed to the output shaft of the driving member, the second transmission wheel is fixed to the rotating shaft and the loading mechanism is connected to the second transmission wheel. The gears of the first transmission wheel and the second transmission wheel are engaged with each other.

8. The mixing device according to claim 7, characterized in that: The number of teeth of the first transmission wheel is smaller than the number of teeth of the second transmission wheel, and / or the diameter of the first transmission wheel is smaller than the diameter of the second transmission wheel.

9. The mixing device according to claim 1, characterized in that: The mixing device includes a detection mechanism, which is arranged on the base and opposite to the loading mechanism, and is used to detect the rotation angle of the loading mechanism.

10. A quality control auxiliary device, characterized in that: The mixing device comprises the mixing device according to any one of claims 1 to 9.

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