Fermentation device for biological medicine molecular experiment

Abstract

The utility model discloses a fermentation device for a biological medicine molecular experiment. The fermentation device comprises an oxygen supply mechanism, a servo motor and an oxygen supply pump, wherein the servo motor and the oxygen supply pump are mounted at the top of the oxygen supply mechanism; a cleaning mechanism is arranged in the feeding mechanism, and one end of the cleaning mechanism is in threaded connection with the end part of the roll shaft; the oxygen supply mechanism comprises a reaction kettle, one side of the bottom of the reaction kettle is fixedly connected with a discharge valve, and the top of the reaction kettle is connected with a sealing cover in a clamping manner; wherein one side of the top of the sealing cover is fixedly connected with a discharging valve, the center position of the top of the sealing cover is fixedly connected with a fixing frame, one side of the fixing frame is fixedly connected with a servo motor, and the oxygen supply mechanism is arranged, so that oxygen cannot be uniformly conveyed into the reaction kettle, and organisms in the reaction kettle can be uniformly mixed; by arranging the cleaning mechanism, the inner wall of the reaction kettle can be quickly cleaned, and the practicability of the device is improved.

Description

Technical Field

[0001] The utility model relates to the technical field of biomedical molecular experiments, in particular to a fermentation device used for biomedical molecular experiments. Background Art

[0002] Biopharmaceutical molecule experiments are essential basic experiments in fermentation plants, including small-scale experiments and detection, which all need to be fermented in bio-fermentation equipment. The experimental fermentation of biopharmaceutical molecules is a process research conducted on fermentation tanks. Since biopharmaceutical molecule fermentation requires consideration of ventilation, water, electricity, gas, steam supply, sewage and drainage, etc., and operating space, space and height, it is necessary to ensure safety in the laboratory during small-scale culture strain experiments.

[0003] Publication No. CN218989227U discloses a fermentation device for biomedical molecular experiments, which is provided with a fermentation chamber with a cylindrical cavity inside, and two notches are provided on the outside of the fermentation chamber, and freely extendable blocking partitions and grid window panels are movably installed in the two notches of the fermentation chamber. At the same time, clips for clamping the culture medium are installed on the inner side of the grid window panels. When the blocking partitions and grid window panels are controlled to extend downward, as the base rotates, the load-bearing female rod threadedly connected to the outside of the base can drive the storage top seat to clamp the bottom of the culture medium. At this time, the steam transported to the bottom of the fermentation chamber cavity through the L-shaped air inlet pipe can be fully discharged to the culture medium along the multiple air holes inside the storage top seat, thereby ensuring that small-scale bacterial strains can achieve fermentation experiments in an independent space. However, this patent still has the following problems during actual use:

[0004] Although the steam transported to the bottom of the fermentation chamber through the L-shaped air inlet pipe in this fermentation device for biomedical molecular experiments can be fully discharged toward the culture medium along multiple air holes inside the top seat, the input oxygen cannot be evenly distributed in the culture medium, which can easily cause unbalanced biological fermentation and thus affect the experimental detection results.

[0005] A fermentation device for biomedical molecular experiments is proposed to solve the above problems. Utility Model Content

[0006] The purpose of the present utility model is to provide a fermentation device for biomedical molecular experiments to solve the problem raised in the above-mentioned background technology that steam currently transported to the bottom of the inner cavity of the fermentation chamber through an L-shaped air inlet pipe can be fully discharged toward the culture medium along multiple air holes inside the storage top seat, but the input oxygen cannot be evenly distributed in the culture medium, which easily causes unbalanced biological fermentation and thus affects the experimental detection results.

[0007] To achieve the above-mentioned object, the present invention provides the following technical solutions: a fermentation device for biomedical molecular experiments, comprising a feeding mechanism, and a servo motor and a feeding pump installed on the top of the feeding mechanism;

[0008] A cleaning mechanism is provided inside the feeding mechanism, and one end of the cleaning mechanism is threadedly connected to the end of the roller shaft;

[0009] Also includes:

[0010] The feeding mechanism includes a reactor, a discharge valve is fixedly connected to one side of the bottom of the reactor, and a sealing cover is snap-fitted to the top of the reactor;

[0011] Among them, a discharge valve is fixedly connected to one side of the top of the sealing cover, a fixed frame is fixedly connected to the center position of the top of the sealing cover, and one side of the fixed frame is fixedly connected to the servo motor;

[0012] Among them, the output end of the servo motor passes through the fixed frame and is fixedly connected to the driving wheel, one side of the driving wheel is meshed and connected to the driven wheel, the bottom end of the driven wheel is fixedly connected to the roller shaft, and the side of the sealing cover close to the fixed frame is fixedly connected to the supply pump, and the output end of the supply pump passes through the driven wheel and is rotatably connected to the roller shaft.

[0013] Preferably, a bearing is fixedly connected to the outer side of the roller shaft near one end of the driven wheel, the outer side of the bearing is fixedly connected to the sealing cover, the bottom end of the roller shaft is provided with a limiting sleeve, and the bottom of the limiting sleeve is fixedly connected to the reactor.

[0014] Preferably, a plurality of positioning blocks are fixedly connected to the outer side of the roller shaft, the number of the positioning blocks is not less than twenty-four, and the positioning blocks are evenly distributed on the outer side of the roller shaft.

[0015] Preferably, the outer side of the positioning block away from the roller shaft is snap-connected with a sleeve, the inner wall of the sleeve close to the positioning block is snap-connected with a first sealing ring, and the inner wall of the first sealing ring is fit-connected with the positioning block.

[0016] Preferably, one end of the sleeve is fixedly connected to a first spring, one end of the first spring is fixedly connected to a movable block, the outer side of the movable block is slidably connected to the sleeve, the outer side of the movable block away from the end of the first spring is snap-connected with a second sealing ring, one side of the second sealing ring is fit-connected to the sleeve, and a through hole is provided on the side of the movable block close to the second sealing ring.

[0017] Preferably, the cleaning mechanism includes a threaded sleeve, one end of which is threadedly connected to the roller shaft, and the other end of the threaded sleeve is fixedly connected to a positioning cylinder.

[0018] Preferably, a second spring is fixedly connected to the inside of the positioning cylinder, one end of the second spring is fixedly connected to a connecting column, the end of the connecting column away from the second spring passes through the positioning cylinder and is fixedly connected to a brush, and one side of the brush is fitted and connected to the reactor.

[0019] Compared with the prior art, the beneficial effects of the present invention are as follows: the fermentation device for biomedical molecular experiments, by providing a feeding mechanism, not only can oxygen be uniformly delivered to the reactor, but also can evenly mix the organisms in the reactor, thereby improving the fermentation efficiency of the organisms; and by providing a cleaning mechanism, the inner wall of the reactor can be quickly cleaned, thereby improving the practicality of the device. The specific contents are as follows:

[0020] 1. The provision of a feeding mechanism not only ensures uniform oxygen delivery to the reactor, but also enables uniform mixing of the organisms in the reactor, thereby improving the fermentation efficiency of the organisms. The servo motor drives the driving wheel to rotate, and the meshing action between the driving wheel and the driven wheel drives the roller shaft to rotate, thereby uniformly mixing the organisms and raw materials in the reactor. The feeding pump delivers oxygen to the roller shaft, and the airflow squeezes the movable block to compress the first spring, separating the second sealing ring from the sleeve, allowing oxygen to flow into the reactor through the through hole for oxygen delivery. The cooperation between the first spring, the movable block, and the sleeve enables one-way oxygen flow, thereby preventing the organisms and raw materials in the reactor from falling into the roller shaft and causing blockage.

[0021] 2. By setting up a cleaning mechanism, the inner wall of the reactor can be cleaned quickly, thereby improving the practicality of the device. The brush is driven to rotate by the roller shaft, and the centrifugal force is utilized to stretch the second spring while making the brush contact with the inner wall of the reactor, thereby cleaning the inner wall of the reactor. The brush on the roller shaft can be removed for cleaning by utilizing the threaded action between the threaded sleeve and the roller shaft. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] Figure 1 This is a schematic diagram of the front view structure of the utility model;

[0023] Figure 2 For this utility model Figure 1 Schematic diagram of the front section structure;

[0024] Figure 3 For this utility model Figure 2 A in the middle is an enlarged structural diagram;

[0025] Figure 4 For this utility model Figure 2 Enlarged structural diagram of the cleaning mechanism in the middle;

[0026] Figure 5 For this utility model Figure 4Schematic diagram of the side cross-sectional structure of the middle sleeve;

[0027] Figure 6 For this utility model Figure 5 Schematic diagram of the structure of the first spring in the compressed state.

[0028] In the figure: 1. feeding mechanism; 101. reactor; 102. discharge valve; 103. sealing cover; 104. unloading valve; 105. fixed frame; 106. servo motor; 107. driving wheel; 108. driven wheel; 109. roller; 110. bearing; 111. limiting sleeve; 112. positioning block; 113. sleeve; 114. first sealing ring; 115. first spring; 116. movable block; 117. second sealing ring; 118. through hole; 119. feeding pump; 2. cleaning mechanism; 201. threaded sleeve; 202. positioning cylinder; 203. second spring; 204. connecting column; 205. brush. DETAILED DESCRIPTION

[0029] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the implementation regulations described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0030] See also Figure 1-6 The present invention provides a technical solution: a fermentation device for biomedical molecular experiments, comprising a feeding mechanism 1, and a servo motor 106 and a feeding pump 119 mounted on the top of the feeding mechanism 1; a cleaning mechanism 2 is provided inside the feeding mechanism 1, and one end of the cleaning mechanism 2 is threadedly connected to the end of a roller 109; the feeding mechanism 1 includes a reactor 101, a discharge valve 102 is fixedly connected to one side of the bottom of the reactor 101, and a sealing cover 103 is snap-connected to the top of the reactor 101. Opening the sealing cover 103 facilitates cleaning the interior of the reactor 101;

[0031] A discharge valve 104 is fixedly connected to one side of the top of the sealing cover 103, a fixed frame 105 is fixedly connected to the center of the top of the sealing cover 103, and one side of the fixed frame 105 is fixedly connected to the servo motor 106.

[0032] The output end of the servo motor 106 passes through the fixed frame 105 and is fixedly connected to the driving wheel 107. One side of the driving wheel 107 is meshedly connected to the driven wheel 108. The bottom end of the driven wheel 108 is fixedly connected to the roller shaft 109. The side of the sealing cover 103 near the fixed frame 105 is fixedly connected to the supply pump 119. The output end of the supply pump 119 passes through the driven wheel 108 and is rotatably connected to the roller shaft 109. A through hole is opened in the roller shaft 109. One end of the through hole is connected to the supply pump 119, and the other end of the through hole is connected to the positioning block 112, thereby enabling oxygen to flow into the sleeve 113.

[0033] A bearing 110 is fixedly connected to the outer side of the roller shaft 109 near the driven wheel 108. The outer side of the bearing 110 is fixedly connected to the sealing cover 103. A limiting sleeve 111 is provided on the bottom end of the roller shaft 109. The bottom of the limiting sleeve 111 is fixedly connected to the reactor 101. The setting of the limiting sleeve 111 improves the rotational stability of the roller shaft 109.

[0034] A plurality of positioning blocks 112 are fixedly connected to the outside of the roller shaft 109. The number of positioning blocks 112 is no less than twenty-four, and the positioning blocks 112 are evenly distributed on the outside of the roller shaft 109. A sleeve 113 is engaged with the outside of the end of the positioning block 112 away from the roller shaft 109. A first sealing ring 114 is engaged with the inner wall of the sleeve 113 near the end of the positioning block 112. The inner wall of the first sealing ring 114 is in close contact with the positioning block 112. The provision of the first sealing ring 114 can improve the sealing between the positioning block 112 and the sleeve 113.

[0035] One end of the sleeve 113 is fixedly connected to a first spring 115, and one end of the first spring 115 is fixedly connected to a movable block 116. The outer side of the movable block 116 is slidably connected to the sleeve 113. The outer side of the movable block 116 away from the end of the first spring 115 is engaged with a second sealing ring 117. One side of the second sealing ring 117 is in close contact with the sleeve 113. A through hole 118 is formed on the side of the movable block 116 close to the second sealing ring 117. The cooperation between the first spring 115, the movable block 116 and the sleeve 113 can achieve one-way flow of oxygen, thereby preventing the organisms and raw materials in the reactor 101 from falling into the roller 109 and causing blockage.

[0036] The cleaning mechanism 2 includes a threaded sleeve 201, one end of which is threadedly connected to the roller shaft 109, and the interior of the other end of the threaded sleeve 201 is fixedly connected to a positioning cylinder 202, and the interior of the positioning cylinder 202 is fixedly connected to a second spring 203, and one end of the second spring 203 is fixedly connected to a connecting column 204, and the end of the connecting column 204 away from the second spring 203 passes through the positioning cylinder 202 and is fixedly connected to a brush 205, one side of the brush 205 is fitly connected to the reactor 101, and the brush 205 on the roller shaft 109 can be removed by utilizing the threaded action between the threaded sleeve 201 and the roller shaft 109.

[0037] Working principle: Before using this fermentation device for biomedical molecular experiments, it is necessary to check the overall condition of the device to ensure that it can work normally. Figure 1 - Figure 6 As shown, first, the discharge valve 102 is closed and the raw materials and organisms are poured into the reactor 101 through the discharge valve 104. The servo motor 106 is started to drive the driving wheel 107 to rotate. The meshing action between the driving wheel 107 and the driven wheel 108 drives the roller 109 to rotate, so that the organisms and raw materials in the reactor 101 are evenly mixed. At the same time, the feeding pump 119 is started to deliver oxygen to the roller 109. The oxygen flow squeezes the movable block 116 to compress the first spring 115, and the second sealing ring 117 is separated from the sleeve 113, so that oxygen flows into the reactor 101 through the through hole 118 to supply oxygen. At the same time, the cooperation between the first spring 115, the movable block 116 and the sleeve 113 can achieve one-way flow of oxygen, thereby preventing the organisms and raw materials in the reactor 101 from falling into the roller 109 and causing blockage.

[0038] Secondly, when the inner wall of the reactor 101 needs to be cleaned, the cleaning agent is poured into the reactor 101 and the brush 205 is installed on the end of the roller 109. The roller 109 drives the brush 205 to rotate. By utilizing the action of centrifugal force, the second spring 203 can be stretched while the brush 205 contacts the inner wall of the reactor 101, so that the inner wall of the reactor 101 can be cleaned. When the brush 205 needs to be cleaned, the roller 109 is taken out of the reactor 101 and the threaded sleeve 201 is rotated. By utilizing the threaded action between the threaded sleeve 201 and the roller 109, the brush 205 on the roller 109 can be removed and cleaned.

[0039] Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art can still modify the technical solutions described in the aforementioned embodiments, or make equivalent substitutions for some of the technical features therein. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the scope of protection of the present invention.

Claims

1. A fermentation device for biomedical molecular experiments, comprising a feeding mechanism (1), and a servo motor (106) and a feeding pump (119) mounted on the top of the feeding mechanism (1); A cleaning mechanism (2) is provided inside the feeding mechanism (1), and one end of the cleaning mechanism (2) is threadedly connected to the end of the roller shaft (109); It is characterized in that Also includes: The feeding mechanism (1) comprises a reaction kettle (101), a discharge valve (102) is fixedly connected to one side of the bottom of the reaction kettle (101), and a sealing cover (103) is snap-connected to the top of the reaction kettle (101); A discharge valve (104) is fixedly connected to one side of the top of the sealing cover (103), a fixed frame (105) is fixedly connected to the center of the top of the sealing cover (103), and one side of the fixed frame (105) is fixedly connected to the servo motor (106); The output end of the servo motor (106) passes through the fixed frame (105) and is fixedly connected to the driving wheel (107); one side of the driving wheel (107) is meshedly connected to the driven wheel (108); the bottom end of the driven wheel (108) is fixedly connected to the roller (109); the side of the sealing cover (103) close to the fixed frame (105) is fixedly connected to the feeding pump (119); the output end of the feeding pump (119) passes through the driven wheel (108) and is rotationally connected to the roller (109).

2. A fermentation device for biopharmaceutical molecular experiments according to claim 1, characterized in that: A bearing (110) is fixedly connected to the outer side of one end of the roller shaft (109) close to the driven wheel (108), and the outer side of the bearing (110) is fixedly connected to the sealing cover (103). A limiting sleeve (111) is provided on the bottom end of the roller shaft (109), and the bottom of the limiting sleeve (111) is fixedly connected to the reactor (101).

3. A fermentation device for biopharmaceutical molecular experiments according to claim 2, characterized in that: A plurality of positioning blocks (112) are fixedly connected to the outer side of the roller shaft (109), the number of the positioning blocks (112) is no less than twenty-four, and the positioning blocks (112) are evenly distributed on the outer side of the roller shaft (109).

4. A fermentation device for biopharmaceutical molecular experiments according to claim 3, characterized in that: The outer side of the positioning block (112) away from the roller shaft (109) is snap-connected with a sleeve (113), and the inner wall of the sleeve (113) close to the end of the positioning block (112) is snap-connected with a first sealing ring (114), and the inner wall of the first sealing ring (114) is closely connected to the positioning block (112).

5. A fermentation device for biopharmaceutical molecular experiments according to claim 4, characterized in that: One end of the sleeve (113) is fixedly connected to a first spring (115), one end of the first spring (115) is fixedly connected to a movable block (116), the outer side of the movable block (116) is slidably connected to the sleeve (113), the outer side of the movable block (116) away from one end of the first spring (115) is snap-connected to a second sealing ring (117), one side of the second sealing ring (117) is fitted and connected to the sleeve (113), and a through hole (118) is provided on the side of the movable block (116) close to the second sealing ring (117).

6. The fermentation device for biopharmaceutical molecular experiments according to claim 1, characterized in that: The cleaning mechanism (2) comprises a threaded sleeve (201), one end of the threaded sleeve (201) is threadedly connected to the roller shaft (109), and the other end of the threaded sleeve (201) is fixedly connected to a positioning cylinder (202) inside.

7. A fermentation device for biopharmaceutical molecular experiments according to claim 6, characterized in that: A second spring (203) is fixedly connected to the interior of the positioning cylinder (202), one end of the second spring (203) is fixedly connected to a connecting column (204), one end of the connecting column (204) away from the second spring (203) passes through the positioning cylinder (202) and is fixedly connected to a brush (205), and one side of the brush (205) is in close contact with the reactor (101).

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