Protein stock solution freeze-drying tray
By introducing inert gas into the lyophilized dish to accelerate the dissipation of water, the problem of low lyophilization efficiency of protein stock solution is solved, and a more efficient lyophilization effect is achieved.
Patent Information
- Application Number
- CN202422525290.3
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-10-18
- Publication Date
- 2025-08-19
- Estimated Expiration
- 2034-10-18
AI Technical Summary
When existing lyophilized dryers lyophilized, moisture is difficult to escape, resulting in low lyophilized drying efficiency.
A protein stock solution freeze-drying dish is designed. By inert gas such as carbon dioxide or nitrogen during the lyophilization process, the gas is used to accelerate the dissipation of water and improve the lyophilization efficiency.
The evaporation of water vapor is accelerated through gas inlet, which significantly improves the lyophilization efficiency.
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Figure CN223243152U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of freeze-drying, in particular to a protein stock solution freeze-drying tray. Background Art
[0002] Freeze-drying is a common drying method used in pharmaceutical production. Currently used freeze dryers load the freeze-dried material into a freeze-drying tray, which is then placed inside the freeze dryer. The freeze-dried material is freeze-dried by pressurizing and cooling. During the freeze-drying process, the fluid freeze-dried material is in a static state, and the moisture inside the static freeze-dried material is difficult to escape, resulting in low freeze-drying efficiency. Protein stock solutions typically refer to high-concentration protein solutions that have not been treated or diluted in any way. These solutions are widely used in biotechnology, pharmaceuticals, food processing, and other fields. However, these protein stock solutions contain a lot of water, and due to their high viscosity, they have a significant impact on freeze-drying. Utility Model Content
[0003] The utility model provides a protein stock solution freeze-drying tray to overcome the deficiencies of the above-mentioned prior art, solves the problem of low freeze-drying efficiency of the protein stock solution, and has strong practicality.
[0004] In order to achieve the purpose of this utility model, the following technologies are proposed:
[0005] A protein liquid freeze-drying tray comprises a lower rectangular tray, the upper end of which is provided with a lower convex edge, the upper end cover of which is provided with an upper cover, the upper cover being provided with a plurality of holes for facilitating the discharge of water vapor. The lower end of the upper cover is provided with an upper convex edge, the upper cover being provided with a distribution plate, the distribution plate being provided with a plurality of flow channels, one end of the flow channels being closed and the other end being provided with a connecting pipe head, the distribution plate being provided with a plurality of lower extension pipes, the upper ends of the lower extension pipes being connected to the flow channels, the lower ends of the lower extension pipes being provided with an upper circular cover, the lower end of the upper circular cover being provided with an air outlet tray, the outer circumference of the air outlet tray being provided with a plurality of air outlet holes, and the air outlet tray being placed on the lower bottom of the lower rectangular tray. During the freeze-drying process, an inert gas, such as carbon dioxide or nitrogen, is introduced into the freeze-drying tray so that the gas is passed into the protein liquid through the lower ends of the lower extension pipes. During the freeze-drying process, the discharge of the gas can accelerate the escape of water in the protein liquid, thereby improving the efficiency of the freeze-drying.
[0006] Furthermore, in order to facilitate operations such as opening the upper cover, a pair of concave handles are provided on the upper cover.
[0007] Furthermore, in order to facilitate the extraction of the lower extension tube from the freeze-dried material and reduce the resistance during the extraction, the upper circular cover has a conical structure with the upper end being the small end.
[0008] Furthermore, in order to prevent the liquid from entering the lower extension tube when the lower extension tube is extended into the protein raw liquid and no gas is filled in, thereby blocking the lower end of the lower extension tube, a plurality of air outlet nozzles are provided on the outer periphery of the air outlet disk, and a conical hole is provided at the outer end of the air outlet nozzle, and the inner end of the conical hole is a small end. The conical hole is connected with the air outlet hole, and a movable tube is movably provided in the air outlet hole, and an inner ring is provided at the inner end of the movable tube, and a conical head is provided at the outer end of the movable tube, and the inner end of the conical head is a small end, and a connecting hole is connected on the cone wall of the conical head, and a spring is provided on the inner end of the movable tube, and the spring is located in the air outlet disk.
[0009] Furthermore, in order to ensure the stability of the connection between the upper cover and the lower rectangular plate, a pair of side panels are provided on both sides of the upper cover, and a first transverse hole is provided on the side panel, and an inclined hole is provided at the outer end of the first transverse hole. The outer end of the inclined hole extends downward at an angle, and a second transverse hole is provided at the outer end of the inclined hole. Screws are movably provided in the first transverse hole, the inclined hole and the second transverse hole, and a concave clamping plate is provided at the inner end of the screw, and the lower end of the concave clamping plate is clamped on the lower convex edge.
[0010] Furthermore, in order to prevent the concave card from falling during the clamping process, an L-shaped elastic card is provided at the outer end of the side plate.
[0011] Furthermore, in order to limit the concave clamping plate, a limiting side plate is provided on the lower wall of the lower convex edge.
[0012] The advantages of the above technical solution are:
[0013] The utility model accelerates the evaporation of water vapor by introducing gas during freeze-drying, thereby improving the efficiency of freeze-drying. BRIEF DESCRIPTION OF THE DRAWINGS
[0014] In order to make the purpose, technical solutions and advantages of the present invention more clear, the present invention will be described in further detail below with reference to the accompanying drawings.
[0015] Figure 1 A three-dimensional structural diagram of one embodiment is shown.
[0016] Figure 2 An enlarged view of point A is shown.
[0017] Figure 3 A partial cross-sectional view of one embodiment is shown. DETAILED DESCRIPTION
[0018] like Figures 1 to 3 As shown, a protein stock freeze-drying tray includes a lower rectangular tray 1, the upper end of the lower rectangular tray 1 is provided with a lower convex edge 10, the upper end cover of the lower rectangular tray 1 is provided with an upper cover 2, the upper cover 2 is provided with a plurality of holes, the lower end of the upper cover 2 is provided with an upper convex edge 20, and the upper cover 2 is provided with a pair of concave handles 21.
[0019] A distribution plate 3 is installed on the upper cover 2. A plurality of flow channels are opened on the distribution plate 3. One end of the flow channel is closed and a connecting pipe head 30 is provided at the other end. A plurality of downward extension pipes 31 are provided on the distribution plate 3. The upper end of the downward extension pipe 31 is connected to the flow channel. The lower end of the downward extension pipe 31 is provided with an upper circular cover 32. The upper circular cover 32 has a conical structure and the upper end is a small end. The lower end of the upper circular cover 32 is provided with an air outlet plate 33. A plurality of air outlet holes 36 are opened on the outer periphery of the air outlet plate 33. The air outlet plate 33 is placed on the lower bottom of the lower rectangular plate 1.
[0020] A plurality of air outlet nozzles 34 are provided on the outer periphery of the air outlet disk 33, and a conical hole 35 is opened at the outer end of the air outlet nozzle 34, and the inner end of the conical hole 35 is a small end. The conical hole 35 is connected with the air outlet hole 36, and a movable tube 37 is movably provided in the air outlet hole 36, and the inner end of the movable tube 37 is provided with an inner ring 38, and the outer end of the movable tube 37 is provided with a conical head 40, and the inner end of the conical head 40 is a small end, and a connecting hole is connected on the conical wall of the conical head 40, and the inner end of the movable tube 37 is provided with a spring 39, and the spring 39 is located in the air outlet disk 33.
[0021] A pair of side panels 22 are provided on both sides of the upper cover 2, and a first transverse hole 23 is provided on the side panel 22. An inclined hole 24 is provided at the outer end of the first transverse hole 23, and the outer end of the inclined hole 24 extends downwardly at an angle, and a second transverse hole 25 is provided at the outer end of the inclined hole 24. Screws 27 are movably provided in the first transverse hole 23, the inclined hole 24 and the second transverse hole 25, and a concave card 28 is provided at the inner end of the screw 27. The lower end of the concave card 28 is clamped on the lower convex edge 10, and an L-shaped elastic card 26 is provided at the outer end of the side panel 22. A limiting side panel 29 is provided on the lower wall of the lower convex edge 10.
[0022] During operation of this embodiment, the operator fills the lower rectangular plate 1 with the protein stock solution.
[0023] The operator then places the upper cover 2 on the lower rectangular plate 1. During the placement process, the lower extension tube 31 and the air outlet plate 33 will extend into the protein stock solution.
[0024] After the upper cover 2 is installed, the operator pushes the concave card plate 28 inward so that the concave card plate 28 is clamped on the lower convex edge 10 and the upper convex edge 20. When the concave card plate 28 moves inward, the screw 27 is moved from the second transverse hole 25 through the inclined hole 24 to the first transverse hole 23. When the screw 27 is located in the second transverse hole 25, the lower wall of the concave card plate 28 acts on the lower convex edge 10, and finally the concave card plate 28 is limited by the L-shaped elastic card 26. When the concave card plate 28 is limited, the operator places the freeze-drying tray. In the freeze dryer, the inflation connecting pipe is connected to the connecting pipe head 30, and then the door of the freeze dryer is closed, and carbon dioxide is filled into the gas outlet plate 33 through the inflation connecting pipe. When the gas enters, it will eventually enter the gas outlet plate 33 through the lower extension pipe 31, and eventually make the carbon dioxide act on the inner ring 38, thereby making the movable tube 37 move outward, and then the carbon dioxide will be discharged outward through the movable tube 37 and the connecting hole into the protein stock solution, and then the bubbles generated by these gases will escape upward. In this way, the freeze-drying operation can be quickly achieved.
[0025] The above description is merely a preferred embodiment of the present invention and is not intended to limit the present invention. Obviously, those skilled in the art may make various modifications and variations to the present invention without departing from the spirit and scope of the present invention. Therefore, if such modifications and variations fall within the scope of the claims and their equivalents, the present invention is intended to include such modifications and variations.
Claims
1. A protein stock solution freeze-drying plate, characterized in that: The lower rectangular plate (1) comprises a lower convex edge (10) provided at the upper end of the lower rectangular plate (1), an upper cover (2) provided at the upper end of the lower rectangular plate (1), a plurality of holes formed on the upper cover (2), and an upper convex edge (20) provided at the lower end of the upper cover (2); A distribution plate (3) is installed on the upper cover (2), and a plurality of flow channels are opened on the distribution plate (3), one end of the flow channel is closed, and the other end is provided with a connecting pipe head (30), a plurality of lower extension pipes (31) are provided on the distribution plate (3), the upper end of the lower extension pipe (31) is connected to the flow channel, the lower end of the lower extension pipe (31) is provided with an upper circular cover (32), and the lower end of the upper circular cover (32) is provided with an air outlet plate (33), a plurality of air outlet holes (36) are opened on the outer periphery of the air outlet plate (33), and the air outlet plate (33) is placed on the lower bottom of the lower rectangular plate (1).
2. The protein stock solution freeze-drying plate according to claim 1, characterized in that A pair of concave handles (21) are provided on the upper cover (2).
3. The protein stock solution freeze-drying plate according to claim 1, characterized in that: The upper circular cover (32) has a conical structure, and the upper end is a small end.
4. The protein stock solution freeze-drying plate according to claim 1, characterized in that: A plurality of air outlet nozzles (34) are provided on the outer periphery of the air outlet disk (33), a tapered hole (35) is provided at the outer end of the air outlet nozzle (34), the inner end of the tapered hole (35) is a small end, the tapered hole (35) is communicated with the air outlet hole (36), a movable tube (37) is movably provided in the air outlet hole (36), the inner end of the movable tube (37) is provided with an inner ring (38), the outer end of the movable tube (37) is provided with a tapered head (40), the inner end of the tapered head (40) is a small end, and a connecting hole is communicated on the cone wall of the tapered head (40), the inner end of the movable tube (37) is provided with a spring (39), and the spring (39) is located in the air outlet disk (33).
5. The protein stock solution freeze-drying plate according to claim 1, characterized in that: A pair of side plates (22) are respectively provided on both sides of the upper cover (2), a first transverse hole (23) is provided on the side plate (22), an oblique hole (24) is provided at the outer end of the first transverse hole (23), the outer end of the oblique hole (24) extends downwardly, a second transverse hole (25) is provided at the outer end of the oblique hole (24), screws (27) are movably provided in the first transverse hole (23), the oblique hole (24) and the second transverse hole (25), a concave card (28) is provided at the inner end of the screw (27), and the lower end of the concave card (28) is clamped on the lower convex edge (10).
6. The protein stock solution freeze-drying plate according to claim 5, characterized in that: An L-shaped elastic card (26) is provided at the outer end of the side plate (22).
7. The protein stock solution freeze-drying plate according to claim 5, characterized in that: A limiting side plate (29) is provided on the lower wall of the lower convex edge (10).
Citation Information
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