Centrifugal machine for biological sample analysis

Through the design of the arc-shaped sealed cover and the inner elastic tightening frame, the problem of test tube shaking in the centrifuge is solved, the stability and safety of the test tube are achieved, and the accuracy of the experiment and the ease of use of the equipment are improved.

CN223288246UActive Publication Date: 2025-09-02DONGGUAN HEMU PHARMACEUTICAL TECHNOLOGY CO LTD
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Patent Information

Application Number
CN202422215718.4
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-09-10
Publication Date
2025-09-02
Estimated Expiration
2034-09-10

AI Technical Summary

Technical Problem

Existing centrifuges are prone to shake during the test tube placement, resulting in inaccurate experimental results and a risk of test tube rupture, and lack of effective fixation between the test tube and the placement seat, increasing the risk of experiment failure.

Method used

Designed with a curved seal cover and an elastic inner tightening frame, the test tube is prevented from shaking by tight contact between the ball and the curved seal cover and provides additional safety protection through a hemispherical transparent cover and protective cover.

Benefits of technology

It enhances the stability of the test tube during high-speed rotation, improves the accuracy and safety of experimental results, and simplifies the installation and maintenance process of the equipment.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a centrifugal machine for biological sample analysis, which belongs to the field of biological sample centrifugal machines and is characterized in that an arc-shaped sealing cover is mounted at a tube opening of a test tube, a semispherical transparent cover is connected to a through hole, an inner elastic abutting frame is mounted in the semispherical transparent cover, an abutting ball is mounted in the inner elastic abutting frame and abuts against the arc-shaped sealing cover, and the arc-shaped sealing cover is connected with the semispherical transparent cover. The test tube is prevented from shaking through the abutting ball; a connecting ring is arranged at the lower end of the inner elastic abutting frame, the inner elastic abutting frame is installed on the hemispherical transparent cover through the connecting ring, the hemispherical transparent cover is installed on the upper fixing cover, and disassembly and assembly of the hemispherical transparent cover are facilitated. The test tube is prevented from shaking during high-speed rotation, and the stability in the centrifugal process is enhanced through tight contact between the abutting ball and the arc-shaped sealing cover. Real-time observation of the test tube is provided, and the transparent characteristic of the hemispherical transparent cover allows a user to clearly see the centrifugal state of the test tube and the biological sample. And the hemispherical transparent cover is tightly connected with the upper fixing cover through the threaded connecting part.
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Description

Technical Field

[0001] The utility model relates to the field of biological sample centrifuges, in particular to a centrifuge for biological sample analysis. Background Art

[0002] Centrifuges, a crucial laboratory instrument in biological sample analysis, rely on centrifugal force to efficiently separate components in a mixture based on density differences. Their operating principle relies on high-speed rotation driven by a motor, creating a powerful centrifugal field within a centrifuge tube or bottle. Centrifuges are categorized into various types based on diverse research needs, including benchtop centrifuges, ultracentrifuges, and refrigerated centrifuges, each tailored to meet varying levels of experimental requirements.

[0003] Benchtop centrifuges, a common laboratory instrument, are widely used in basic experimental processes such as cell separation and plasma preparation. Ultracentrifuges, with their superior separation capabilities, play a vital role in the fine separation of viral particles and macromolecular complexes. Refrigerated centrifuges are particularly designed to protect heat-sensitive samples such as proteins and enzymes, ensuring successful centrifugal separation even at low temperatures.

[0004] However, in actual centrifuge use, placing test tubes directly on the support has significant drawbacks. Test tubes are prone to shaking during centrifugation, which not only reduces the accuracy of experimental results but can also lead to serious consequences such as tube rupture, contaminating samples and posing a safety threat to operators. Furthermore, the lack of effective fixation between the test tubes and the support makes it difficult to maintain stability during high-speed rotation, further increasing the risk of experimental failure. Utility Model Content

[0005] The main purpose of the present invention is to provide a centrifuge for biological sample analysis, which can effectively solve the problems raised in the background technology.

[0006] In order to achieve the above purpose, the technical solution adopted by the utility model is:

[0007] A centrifuge for biological sample analysis, comprising a centrifuge body, a control panel, an upper fixed cover, a through hole, a truncated pedestal, and a test tube. The upper fixed cover and the control panel are respectively located on the upper end and upper inclined surface of the centrifuge body. The through hole is located on the end surface of the upper fixed cover. The truncated pedestal is mounted on the centrifuge body and protrudes above the through hole. The test tube is inserted into the inner wall of the truncated pedestal.

[0008] The tube mouth of the test tube is installed with an arc-shaped sealing cover, the through hole is connected to a hemispherical transparent cover, and an internal elastic tight frame is installed in the cover of the hemispherical transparent cover, and a tight ball is installed in the frame of the internal elastic tight frame. The tight ball presses against the arc-shaped sealing cover to prevent the test tube from shaking;

[0009] The lower end of the inner elastic abutting frame is provided with a connecting ring, which is mounted on the hemispherical transparent cover through the connecting ring. The hemispherical transparent cover is mounted on the upper fixed cover, which facilitates the disassembly and assembly of the hemispherical transparent cover.

[0010] As a further optional solution of the present invention, the rear end of the centrifuge body is provided with a hinge device, and a protective cover is installed through the hinge device. The protective cover covers the upper end of the centrifuge body and the hemispherical transparent cover. The lower end edge of the protective cover is provided with a rubber strip, which is tightly attached to the upper fixed cover through the rubber strip;

[0011] As a further optional solution of the present invention, the pedestal is a test tube placement table, which is connected to the internal rotating mechanism of the centrifuge body, and the centrifugal operation is achieved by rotating the pedestal and the test tube through the rotating mechanism inside the centrifuge body;

[0012] As a further optional solution of the present invention, the arc-shaped sealing cover is divided into an embedded cover and an arc-shaped portion. The arc-shaped portion is located at the top of the embedded cover. The embedded cover is inserted into the upper end of the test tube. A sealing ring is provided at the connection between the embedded cover and the test tube. The arc surface of the arc portion contacts the ball and fits with it. The arc surface of the arc portion is smooth.

[0013] As a further optional solution of the present invention, the intersection of the axis extensions of the plurality of test tubes is located inside the abutment ball, and the abutment ball is welded and fixed to an internal elastic abutment frame, which is made of an elastic metal material and is composed of a plurality of "C"-shaped elastic strips;

[0014] As a further optional solution of the present invention, the hemispherical transparent cover is divided into a hemispherical cover and a threaded connection part. The threaded connection part is located at the lower cover opening of the hemispherical cover and is connected to the upper fixed cover through the threaded connection part. The shaking of the tightening ball, arc-shaped sealing cover and test tube can be observed through the hemispherical cover.

[0015] Compared with the prior art, the present invention has the following beneficial effects:

[0016] This utility model prevents the test tube from shaking during high-speed rotation by ensuring close contact between the abutting ball and the arc-shaped sealing cover, thereby enhancing stability during the centrifugation process. It also provides real-time observation of the test tube, and the transparent nature of the hemispherical transparent cover allows the user to clearly see the centrifugation status of the test tube and biological sample.

[0017] The hemispherical transparent cover is tightly connected to the upper fixed cover via a threaded connection, simplifying the installation process and making assembly and disassembly convenient. Providing additional safety, the hemispherical transparent cover and protective cover effectively prevent the intrusion of external impurities and accidental collisions, enhancing the overall safety of the device. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 It is a schematic diagram of the overall structure of the utility model;

[0019] Figure 2 This is a diagram showing the overall structure of the utility model;

[0020] Figure 3 This is a side view of the overall structure of the utility model;

[0021] Figure 4 This is an exploded view of the hemispherical transparent cover, the round table seat and the centrifuge body of the utility model;

[0022] Figure 5 This is an exploded view of the hemispherical transparent cover, the abutting ball and the internal elastic abutting frame of the present invention.

[0023] In the figure: 1. Centrifuge body; 2. Control panel; 3. Upper fixed cover; 4. Hinge device; 5. Protective cover; 6. Through hole; 7. Round table base; 8. Test tube; 9. Arc-shaped sealing cover; 10. Hemispherical transparent cover; 11. Internal elastic tightening frame; 12. Tightening ball; 13. Connecting ring. DETAILED DESCRIPTION

[0024] In order to make the technical means, creative features, objectives and effects achieved by the present invention easier to understand, the present invention is further described below in conjunction with specific implementation methods.

[0025] Example 1

[0026] exist Figures 1 to 5 Within the scope of the detailed description, this embodiment provides a centrifuge designed specifically for biological sample analysis, featuring a sophisticated structure and powerful functionality. The core components of the centrifuge include a centrifuge body 1, a control panel 2, an upper fixed cover 3, a through hole 6, a truncated base 7, a test tube 8, and a series of carefully designed auxiliary devices.

[0027] Centrifuge body 1, the supporting framework of the entire device, is stable and sturdy. Its upper end supports the upper fixed cover 3, while the upper slope cleverly houses the control panel 2 for easy user operation. Through-hole 6 is prominently visible on the end face of upper fixed cover 3, serving not only as a passage but also as a bridge connecting the inner and outer worlds. Round pedestal 7, the dedicated stage for test tube 8, is cleverly mounted on centrifuge body 1 and proudly protrudes above through-hole 6, providing a stable rotating platform for test tube 8.

[0028] Test tube 8, serving as a biological sample carrier, features a carefully designed curved sealing cap 9 at its mouth. This design not only ensures a tight seal around the sample but also enhances stability during centrifugation through its unique structure. The curved sealing cap 9 consists of an embedded cap and an arc-shaped portion. The embedded cap extends deep into the interior of test tube 8, and a sealing ring is fitted at the junction, ensuring a foolproof seal. The smooth curved surface of the arc-shaped portion perfectly mates with the abutting ball 12 within the hemispherical transparent cover 10. The close contact between the abutting ball 12 effectively prevents the test tube 8 from shaking during high-speed rotation.

[0029] The hemispherical transparent cover 10 is not only aesthetically pleasing but also practical. It houses an internal elastic support frame 11, constructed from an elastic metal material and composed of multiple C-shaped elastic strips. This ensures both sufficient elasticity and excellent stability. Within the internal elastic support frame 11, the support ball 12 sits securely in place. Welded to the frame, it maintains its position during centrifugation. The transparent nature of the hemispherical transparent cover 10 allows the user to clearly observe the real-time status of the support ball 12, the arc-shaped sealing cap 9, and the test tube 8.

[0030] Furthermore, the hemispherical transparent cover 10 is tightly connected to the upper fixed cover 3 via a threaded connection at its lower end. This design not only simplifies the installation process but also makes the assembly and disassembly of the hemispherical transparent cover 10 extremely convenient. The precise connection between the truncated base 7 and the internal rotating mechanism of the centrifuge body 1 ensures smooth centrifugation, enabling rapid and efficient centrifugation of the test tube 8 and the biological sample contained therein.

[0031] Example 2

[0032] This embodiment is further optimized and upgraded based on the first embodiment. In addition to retaining all the advantages of the original structure, a hinge device 4 and a protective cover 5 are added to the rear end of the centrifuge body 1.

[0033] The introduction of the hinge mechanism 4 allows the protective cover 5 to be flexibly opened and closed on the centrifuge body 1, providing additional safety protection for the centrifuge. The protective cover 5 itself cleverly covers the upper end of the centrifuge body 1 and the hemispherical transparent cover 10, effectively preventing the intrusion of external impurities and accidental collisions. The lower edge of the protective cover 5 is also thoughtfully equipped with a rubber strip. This design not only enhances the seal between the protective cover 5 and the upper fixed cover 3, but also reduces noise and wear during opening and closing due to its soft material.

[0034] The centrifuge for biological sample analysis proposed in this embodiment, while retaining the advantages of the original structure, further improves the overall performance and user experience of the device by adding design elements such as the hinge device 4 and the protective cover 5.

[0035] Instructions: Ensure centrifuge body 1 is placed firmly on the work surface and powered on. Open control panel 2 and set appropriate parameters such as speed, time, and temperature based on the centrifugation requirements of the biological sample. Place test tube 8 on the pedestal 7, ensuring it is secure and stable. Insert the recessed portion of arc-shaped sealing cover 9 into test tube 8 and tighten to ensure a tight seal.

[0036] Align the hemispherical transparent cover 10, assembled with the internal elastic abutment frame 11 and abutment balls 12, with the through-hole 6 of the upper fixed cover 3. Securely connect the hemispherical transparent cover 10 to the upper fixed cover 3 via the threaded connection, ensuring a seamless connection. After confirming that all components are correctly installed, press the start button on the control panel 2 to begin centrifuge operation. During centrifugation, the abutment balls 12 inside the hemispherical transparent cover 10 maintain close contact with the curved portion of the arc-shaped sealing cover 9, effectively preventing the test tube 8 from shaking.

[0037] Through the transparent hemispherical cover 10, observe the centrifugal status of test tube 8 and the biological sample. Record key data during the centrifugation process, such as rotation speed and temperature. When the centrifuge reaches the set time, the centrifuge automatically stops. After the centrifuge stops completely, open the hemispherical cover 10 and remove the test tube 8 for subsequent processing.

[0038] When pressing to prevent shaking: After the test tube 8 is installed and fixed on the pedestal seat 7, the arc-shaped portion of the arc-shaped sealing cover 9 makes initial contact with the pressing ball 12 in the hemispherical transparent cover 10. As the centrifuge starts to rotate, the "C"-shaped elastic strip of the internal elastic pressing frame 11 begins to play a role, exerting a certain elastic force on the pressing ball 12. Under the action of the elastic force, the pressing ball 12 fits tightly against the arc-shaped portion of the arc-shaped sealing cover 9 to form a stable contact surface. During high-speed rotation, the test tube 8 may have a tendency to shake due to inertia. However, due to the close contact of the pressing ball 12 and the elastic force of the internal elastic pressing frame 11, the shaking of the test tube 8 is effectively suppressed to maintain dynamic balance.

[0039] The transparent material of the hemispherical transparent cover 10 not only facilitates observation but also provides a protective function, preventing the test tube 8 from accidentally falling off or breaking during centrifugation. Even in the event of an accident, the protective cover 5 provides additional safety protection, reducing potential risks. This centrifuge for biological sample analysis ensures the stability of the test tube 8 during centrifugation, improving the accuracy and reliability of biological sample analysis.

[0040] The standard parts used in this utility model can all be purchased from the market, and special-shaped parts can be customized according to the description in the specification and the drawings. The specific connection methods of each part adopt conventional means such as mature bolts, rivets, welding, etc. in the existing technology. The machinery, parts and equipment all adopt conventional models in the existing technology, and the electric fusion connection adopts the conventional connection method in the existing technology, which will not be described in detail here.

[0041] The above are only preferred specific implementation methods of the present invention, but the protection scope of the present invention is not limited to them. Any technician familiar with the technical field can make equivalent replacements or changes based on the technical solution and utility model concept of the present invention within the technical scope disclosed by the present invention, and they should be covered by the protection scope of the present invention.

Claims

1. A centrifuge for biological sample analysis, comprising a centrifuge body (1), a control panel (2), an upper fixed cover (3), a through hole (6), a truncated pedestal (7) and a test tube (8), wherein the upper fixed cover (3) and the control panel (2) are respectively located on the upper end and the upper inclined surface of the centrifuge body (1), the through hole (6) is located on the end surface of the upper fixed cover (3), the truncated pedestal (7) is mounted on the centrifuge body (1) and protrudes from the through hole (6), and the test tube (8) is inserted into the inner wall of the truncated pedestal (7), characterized in that: The tube mouth of the test tube (8) is provided with an arc-shaped sealing cover (9), the through hole (6) is connected with a hemispherical transparent cover (10), and an inner elastic tightening frame (11) is provided inside the cover of the hemispherical transparent cover (10), and a tightening ball (12) is provided inside the frame of the inner elastic tightening frame (11), and the tightening ball (12) presses against the arc-shaped sealing cover (9), thereby preventing the test tube (8) from shaking. The lower end of the inner elastic abutting frame (11) is provided with a connecting ring (13), which is mounted on the hemispherical transparent cover (10) through the connecting ring (13). The hemispherical transparent cover (10) is mounted on the upper fixed cover (3), so as to facilitate the disassembly and assembly of the hemispherical transparent cover (10).

2. A centrifuge for biological sample analysis according to claim 1, characterized in that: The rear end of the centrifuge body (1) is provided with a hinge device (4), and a protective cover (5) is installed through the hinge device (4). The protective cover (5) covers the upper end of the centrifuge body (1) and the hemispherical transparent cover (10). The lower end edge of the protective cover (5) is provided with a rubber strip, and is tightly attached to the upper fixed cover (3) through the rubber strip.

3. A centrifuge for biological sample analysis according to claim 1 or 2, characterized in that: The pedestal seat (7) is a table for placing the test tube (8). The pedestal seat (7) is connected to the internal rotating mechanism of the centrifuge body (1). The centrifugal operation is achieved by rotating the pedestal seat (7) and the test tube (8) through the internal rotating mechanism of the centrifuge body (1).

4. The centrifuge for biological sample analysis according to claim 3, characterized in that: The arc-shaped sealing cover (9) is divided into an embedded cover and an arc-shaped portion. The arc-shaped portion is located at the top of the embedded cover. The embedded cover is inserted into the upper end of the test tube (8). A sealing ring is provided at the connection between the embedded cover and the test tube (8). The arc surface of the arc-shaped portion contacts the ball (12) and is adapted thereto. The arc surface of the arc-shaped portion is designed to be smooth.

5. The centrifuge for biological sample analysis according to claim 4, characterized in that: The intersection of the axis extensions of the plurality of test tubes (8) is located within the abutting ball (12), and the abutting ball (12) is welded and fixed to the inner elastic abutting frame (11). The inner elastic abutting frame (11) is made of an elastic metal material and is composed of a plurality of "C"-shaped elastic strips.

6. The centrifuge for biological sample analysis according to claim 5, characterized in that: The hemispherical transparent cover (10) is divided into a hemispherical cover and a threaded connection portion. The threaded connection portion is located at the lower cover opening of the hemispherical cover and is connected to the upper fixed cover (3) through the threaded connection portion. The shaking of the pressing ball (12), the arc-shaped sealing cover (9) and the test tube (8) can be observed through the hemispherical cover.