Packaging structure suitable for double-marking method diagnostic reagent
By designing a packaging structure suitable for the double-labeling method, the problem of the traditional detection kit breaking of the reagent tube during transportation is solved, and a high-integrated packaging structure is provided to ensure the safety and convenience of the reagents and probes, and support multi-sample detection.
Patent Information
- Application Number
- CN202422272234.3
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-09-18
- Publication Date
- 2025-09-02
- Estimated Expiration
- 2034-09-18
AI Technical Summary
Traditional detection kits are prone to damage to the reagent tube due to collision and extrusion during transportation, and the prior art fails to provide a high-integrated packaging structure suitable for double-labeling methods, especially in multiple sample detection scenarios, it is difficult to ensure the safety and convenience of reagents and probes.
A packaging structure including an outer packaging box, an inner liner, a probe box and a triple reagent kit is designed. A multiple storage holes and an isolated reagent cavity are provided in the inner liner. A multiple reagent cavity and material collection hole are provided in the triple reagent box. The probe box is sealed by an aluminum foil bag to ensure the safety and convenience of the reagent and probe during transportation.
It realizes the safety and convenience of reagents and probes during transportation, supports efficient double-label detection, and is suitable for large-scale sample detection.
Smart Images

Figure CN223291455U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the field of diagnostic reagents, in particular to a packaging structure suitable for diagnostic reagents using a double-labeling method. Background Art
[0002] A test kit is a device for detecting a disease, and the device can be packaged during transportation, and the reagents in the package can be taken out for testing when testing is required. Traditional test kits, such as a latent mastitis early diagnosis device disclosed in the utility model patent with authorization publication number CN201518023U, only have 4 bottles of reagents and an ELISA plate in the outer packaging box. Since some of the reagent tubes in the test kit are glass products, they are extremely easy to collide and break. At the same time, the outer packaging box is easily squeezed and deformed by external forces during transportation, thereby pressing on the reagent tubes and causing damage. If the reagent tubes are damaged, the reagents in the container tubes are easily contaminated. Therefore, on the basis of traditional test kits, such as in the prior art of the utility model patent with authorization publication number CN203021568U and the utility model patent with authorization publication number CN212134595U, different reagent bottles are separated by lining or partitions in the outer packaging box to avoid damage.
[0003] The principle of the dual-labeling method is to detect different antigens or markers in the same sample using two different markers (such as antibodies), thereby improving the accuracy and specificity of the test. At the same time, the dual-labeling method can achieve quantitative or qualitative analysis of multiple related substances in a single experiment without the need for duplicate samples, thereby reducing testing costs and improving detection efficiency. However, because the dual-labeling method requires different markers for the detection of the same sample, a more convenient and highly integrated packaging structure is needed for dual-labeling diagnostic reagents. In particular, for applications where multiple samples are tested simultaneously, a reagent packaging structure that can complete dual-labeling detection in large quantities is needed. Utility Model Content
[0004] Therefore, in order to solve the above problems, the present invention provides a packaging structure suitable for diagnostic reagents using a double-labeling method.
[0005] The utility model is realized through the following technical solutions:
[0006] A packaging structure for diagnostic reagents using a double-labeling method, comprising an outer packaging box, an inner liner and a probe box arranged on one side of the inner liner, the inner liner being provided with a first receiving hole and a plurality of second receiving holes and a third receiving hole, respectively, at intervals, the inner liner being provided with two triple test kits of the same shape and a plurality of sub-packaging tubes and sealed cillin bottles, the triple test kit comprising a box body and a box cover covering the top of the box body, the box body of the triple test kit being sequentially formed with a first reagent chamber, a second reagent chamber and a third reagent chamber isolated from each other, the box cover being provided with holes corresponding to the first reagent chamber and the second reagent chamber The position of the third reagent chamber is sequentially provided with a first material extraction hole, a second material extraction hole and a third material extraction hole, a cover handle is provided on the box cover, the box bodies of the two triple test kits are inserted into the first receiving hole, and the cover body of the triple test kit is exposed outside the first receiving hole, the filling tube and the sealed penicillin bottle both include a bottle body and a bottle cap, the bottle body of the filling tube is inserted into the second receiving hole, and the bottle body of the sealed penicillin bottle is inserted into the third receiving hole, the probe box includes a well plate and a cover plate, a plurality of probe holes for storing probes are arranged on the well plate, the cover plate covers the well plate, and the probe box is sealed by an aluminum foil bag.
[0007] Preferably, a circle of limiting grooves is provided on the inner side wall of the cover plate, and a circle of limiting bosses matching the limiting grooves is provided on the outer peripheral edge of the upper surface of the orifice plate.
[0008] Preferably, the inner surface of the cover plate is also provided with a baffle assembly, which includes multiple rows of transverse baffles and multiple columns of longitudinal baffles. The transverse baffles and the longitudinal baffles are arranged in a cross-staggered manner, and when the cover plate is covered on the hole plate, the transverse baffles and the longitudinal baffles are interspersed in the gaps between the probe holes.
[0009] Preferably, a plurality of limiting columns are vertically arranged downward on the inner surface of the cover plate, and the limiting columns are arranged at the intersection of the horizontal baffle and the vertical baffle. The upper surface of the orifice plate is also provided with limiting holes matching the limiting columns, and the limiting holes are located at the intervals between the probe holes.
[0010] Preferably, card slots are provided on the outer walls of the first reagent chamber, the second reagent chamber and the third reagent chamber, and snaps are also provided on the card slots. The box cover of the triple reagent kit is respectively provided with limit blocks of matching shape and position corresponding to the card slots of the first reagent chamber, the second reagent chamber and the third reagent chamber, and the limit blocks are provided with card holes matching the snaps.
[0011] Preferably, the second reagent chamber is staggered with the first reagent chamber and the third reagent chamber on the left and right, and the slots of the first reagent chamber and the third reagent chamber are located on the outer wall on the left side thereof, and the slot of the second reagent chamber is located on the outer wall on the right side thereof. The left side of the box cover is respectively provided with limit blocks of matching shape and position corresponding to the slots of the first reagent chamber and the third reagent chamber, and the right side of the box cover is also provided with limit blocks of matching shape and position corresponding to the slots of the second reagent chamber.
[0012] Preferably, the height of the bottle body of the dispensing tube is greater than the depth of the second receiving hole, and the height of the bottle body of the sealed penicillin bottle is greater than the depth of the third receiving hole.
[0013] Preferably, the outer packaging box is a transparent outer packaging box.
[0014] The beneficial effects of the technical solution of this utility model are mainly reflected in:
[0015] 1. Two triple test kits are arranged in the first storage hole of the inner lining of the packaging structure at the same time. The triple test kit is convenient for real-time detection of samples. Three reagent chambers for storing different detection reagents are arranged in the box body. The two triple test kits are arranged side by side in the first storage hole. The two triple test kits can respectively accommodate different markers and are suitable for dual-label detection. A material extraction hole is provided on the box cover corresponding to each reagent cavity, which facilitates the probe to enter different reagent chambers for reaction, thereby improving the convenience of detection operation. A limiting structure and a snap-fit structure are provided between the box body and the box cover of the triple test kit to ensure the sealing performance of the triple test kit.
[0016] 2. The inner lining of the packaging structure is provided with a first storage hole, a plurality of second storage holes and a third storage hole corresponding to the two triple test kits and a plurality of filling tubes and sealed penicillin bottles. The various storage holes are clearly divided and can ensure that the reagent containers will not be damaged by external force, squeezing or collision during transportation. The filling tubes and sealed penicillin bottles can be used to store various reagents to be added later. At the same time, a probe box is also provided in the outer packaging box, and a large number of probes can be stored in the probe box at the same time. Therefore, a large number of tests can be completed with only one packaging structure.
[0017] 3. The probe box includes a well plate for placing a large number of probes and a cover plate for covering the well plate. Multiple limiting structures are set between the well plate and the cover plate to ensure that the probes in the probe box will not fall out of the probe holes during transportation. In addition, the limiting structure between the well plate and the cover plate and the sealed aluminum foil bag on the outside of the probe box can also ensure the sealing performance inside the probe box to prevent the probes from being contaminated. BRIEF DESCRIPTION OF THE DRAWINGS
[0018] Figure 1 This is a three-dimensional diagram of the packaging structure for diagnostic reagents suitable for the dual-labeling method;
[0019] Figure 2 This is a three-dimensional diagram of the packaging structure for diagnostic reagents used in the dual-labeling method (the outer packaging box and aluminum foil bag are omitted in this case);
[0020] Figure 3 This is a top view of the packaging structure for dual-labeled diagnostic reagents (the outer packaging box and aluminum foil bag are omitted in this case);
[0021] Figure 4 This is a schematic diagram of the internal structure of a packaging structure suitable for a dual-labeling method diagnostic reagent;
[0022] Figure 5 Schematic diagram of the top view of the hole plate and the bottom view of the cover plate in the probe box;
[0023] Figure 6 is a longitudinal cross-sectional view of the probe box;
[0024] Figure 7 It is a schematic diagram of the first structure of two triple test kits;
[0025] Figure 8 is a schematic diagram of the second structure of two triple test kits;
[0026] Figure 9 It is a three-dimensional image of the lining. DETAILED DESCRIPTION
[0027] To more clearly and in detail illustrate the objectives, advantages, and features of the present invention, the following non-limiting description of preferred embodiments is provided for illustration and explanation. This embodiment is merely a typical example of the application of the present invention's technical solution. Any technical solution formed by equivalent substitution or equivalent transformation falls within the scope of protection claimed by the present invention.
[0028] It is also stated that in the description of the scheme, it should be noted that the terms "center", "up", "down", "left", "right", "front", "back", "inside", "outside", etc., indicating the orientation or position relationship, are based on the orientation or position relationship shown in the accompanying drawings, and are only for the convenience of description and simplified description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present invention.
[0029] Furthermore, the terms "first" and "second" in this solution are used for descriptive purposes only and should not be construed as indicating or implying a ranking of importance or implicitly specifying the number of technical features shown. Therefore, features specified as "first" or "second" may explicitly or implicitly include one or more of such features. In this utility model, "plurality" means two or more, unless otherwise specifically defined.
[0030] The utility model discloses a packaging structure suitable for double-labeling diagnostic reagents, such as Figure 1 As shown, it includes an outer packaging box 1. In a preferred embodiment, the outer packaging box 1 is a transparent packaging box. Figure 2-Figure 4 As shown, the outer packaging box 1 is provided with an inner liner 2 and a probe box 3 arranged on one side of the inner liner 2, and the inner liner 2 is provided with a first receiving hole 201 and multiple second receiving holes 202 and a third receiving hole 203 at intervals, and the inner liner 2 is also provided with two triple test kits 4 of the same shape and multiple filling tubes 5 and sealed penicillin bottles 6, and the triple test kit 4 includes a box body 401 and a box cover 402 covering the top of the box body 401, as shown Figure 7 、 Figure 8 As shown, a first reagent chamber 403, a second reagent chamber 404 and a third reagent chamber 405 isolated from each other are formed in sequence in the box body 401 of the triple reagent kit 4, and different reagents can be placed in the three reagent chambers respectively. A first material extraction hole 411, a second material extraction hole 412 and a third material extraction hole 413 are sequentially provided on the box cover 402 at positions corresponding to the first reagent chamber 403, the second reagent chamber 404 and the third reagent chamber 405. In actual application, the probe 7 can pass through different material extraction holes in sequence to extract materials. A cover handle 406 is provided on the box cover 402, which facilitates the removal of the triple reagent kit 4 from the first receiving hole 201 through the cover handle 406, and then the triple reagent kit 4 is cleaned and the reagents in the triple reagent kit 4 are replenished or replaced after completing one test.
[0031] The box bodies 401 of the two triple test kits 4 are inserted into the first receiving hole 201, and the covers of the triple test kits 4 are exposed outside the first receiving hole 201, wherein different triple test kits 4 can accommodate reagents of different detection types, thereby ensuring that the reagent packaging structure is suitable for dual-label detection.
[0032] like Figure 7 、 Figure 8As shown, in some embodiments, the outer walls of the first reagent chamber 403, the second reagent chamber 404, and the third reagent chamber 405 are provided with a slot 407, and the slot 407 is further provided with a buckle 408, and the box cover 402 of the triple reagent box 4 is respectively provided with a limit block 409 of a shape and position matching the slot 407 of the first reagent chamber 403, the second reagent chamber 404, and the third reagent chamber 405, and the limit block 409 is provided with a buckle 408 that matches the buckle 408. The matching card hole 410, when the triple test kit 4 is inserted into the first receiving hole 201, the limit block 409 is embedded in the card slot 407, and the buckle 408 is fixed to the card hole 410, thereby ensuring that the box body 401 and the box cover 402 are fixed; when the triple test kit 4 needs to be cleaned or the reagents inside it need to be replaced, the triple test kit 4 can be taken out from the first receiving hole 201 first, and the buckle 408 and the card hole 410 can be unfastened to remove the box cover 402 from the box body 401.
[0033] like Figure 7 、 Figure 8 As shown, in a preferred embodiment, the second reagent chamber 404 located between the first reagent chamber 403 and the third reagent chamber 405 is staggered left and right with the first reagent chamber 403 and the third reagent chamber 405, and the slots 407 of the first reagent chamber 403 and the third reagent chamber 405 are located on the outer wall on the left side thereof, and the slots 407 of the second reagent chamber 404 are located on the outer wall on the right side thereof. The left side of the box cover 402 is respectively provided with limit blocks 409 of matching shape and position corresponding to the slots 407 of the first reagent chamber 403 and the third reagent chamber 405, and the right side of the box cover 402 is also respectively provided with limit blocks 409 of matching shape and position corresponding to the slots 407 of the second reagent chamber 404, thereby further ensuring the stability of the fixation of the box body 401 and the box cover 402 on both sides of the triple reagent kit 4.
[0034] The dispensing tube 5 and the sealed cillin bottle 6 both include a bottle body and a bottle cap, the bottle cap is sealed and connected to the bottle body, the bottle body of the dispensing tube 5 is inserted into the second receiving hole 202, and the bottle body of the sealed cillin bottle 6 is inserted into the third receiving hole 203; Figures 1-4 As shown, in one embodiment, the height of the bottle body of the dispensing tube 5 is greater than the depth of the second receiving hole 202, and the height of the bottle body of the sealed penicillin bottle 6 is greater than the depth of the third receiving hole 203, thereby ensuring that part of the bottle body and the bottle cap of the dispensing tube 5 and the sealed penicillin bottle 6 are exposed outside the second receiving hole 202 or the third receiving hole 203, making it easy to take out the dispensing tube 5 and the sealed penicillin bottle 6.
[0035] like Figure 4-Figure 6As shown, the probe box 3 includes a well plate 302 and a cover plate 301 . The well plate 302 is provided with a plurality of probe holes 303 for storing probes 7 . The cover plate 301 covers the well plate 302 . The probe box 3 is sealed by an aluminum foil bag 8 .
[0036] In some embodiments, two or more probe boxes 3 are placed in parallel on one side of the lining 2, such as Figure 5 As shown, each of the probe boxes 3 is provided with 100 probe holes 303, so that large-scale sample testing can be achieved. The specific number of the probe boxes 3 can be adjusted according to the amount of spare reagents that can be accommodated in the liner 2, which will not be elaborated here.
[0037] like Figure 5 、 Figure 6 As shown, in some embodiments, a circle of limiting grooves 304 is provided on the inner side wall of the cover plate 301, and a circle of limiting bosses 305 matching the limiting grooves 304 are provided at the outer peripheral edge of the upper surface of the orifice plate 302. When the cover plate 301 covers the top of the orifice plate 302, the limiting bosses 305 are just embedded in the limiting grooves 304. On the one hand, the positioning of the cover plate 301 and the orifice plate 302 is realized to ensure the sealing performance of the combination of the two. On the other hand, the limiting grooves 304 and the limiting bosses 305 are used to limit the cover plate 301, thereby preventing the cover plate 301 from colliding with or squeezing the probe 7.
[0038] like Figure 5 、 Figure 6 As shown, in some embodiments, the inner surface of the cover plate 301 is further provided with a baffle assembly, which includes multiple rows of transverse baffles 306 and multiple columns of longitudinal baffles 307. The transverse baffles 306 and the longitudinal baffles 307 are arranged in a cross-staggered manner, and when the cover plate 301 is covered on the hole plate 302, the transverse baffles and the longitudinal baffles 307 are inserted into the intervals between the probe holes 303 to prevent the transverse baffles and the longitudinal baffles 307 from squeezing the probes 7. At the same time, when the cover plate 301 is covered on the hole plate 302, the multiple probes 7 placed in the hole plate 302 are separated into multiple small areas by the baffle assembly, further In order to improve the airtightness and stability of the storage between the probes 7, in a preferred embodiment, a plurality of limiting columns 308 are vertically arranged downward on the inner surface of the cover plate 301, and the limiting columns 308 are arranged at the intersection of the horizontal baffle 306 and the vertical baffle 307. The upper surface of the orifice plate 302 is also provided with limiting holes 309 matching the limiting columns 308, and the limiting holes 309 are located at the intervals between the probe holes 303. When the cover plate 301 covers the orifice plate 302, the limiting columns 308 are just inserted into the limiting holes 309, further ensuring the accuracy of positioning between the cover plate 301 and the orifice plate 302.
[0039] There are many implementation methods for the present utility model, and all technical solutions formed by equivalent transformation or equivalent transformation fall within the protection scope of the present utility model.
Claims
1. A packaging structure suitable for dual-labeling diagnostic reagents, including an outer packaging box, characterized in that: The outer packaging box is provided with an inner lining and a probe box arranged on one side of the inner lining, the inner lining is provided with a first receiving hole and a plurality of second receiving holes and a third receiving hole at intervals, the inner lining is also provided with two triple test kits of the same shape and a plurality of sub-packaging tubes and sealed cillin bottles, the triple test kit comprises a box body and a box cover covering the top of the box body, the box body of the triple test kit is sequentially formed with a first reagent chamber, a second reagent chamber and a third reagent chamber isolated from each other, the box cover is sequentially provided with the positions corresponding to the first reagent chamber, the second reagent chamber and the third reagent chamber There are a first material extraction hole, a second material extraction hole and a third material extraction hole, and a cover handle is provided on the box cover. The box bodies of two triple test kits are inserted into the first receiving hole, and the cover body of the triple test kit is exposed outside the first receiving hole. The filling tube and the sealed penicillin bottle both include a bottle body and a bottle cap. The bottle body of the filling tube is inserted into the second receiving hole, and the bottle body of the sealed penicillin bottle is inserted into the third receiving hole. The probe box includes a hole plate and a cover plate. A plurality of probe holes for storing probes are arranged on the hole plate, and the cover plate covers the hole plate. The probe box is sealed by an aluminum foil bag.
2. The packaging structure for a dual-labeling diagnostic reagent according to claim 1, characterized in that: A circle of limiting grooves is provided on the inner side wall of the cover plate, and a circle of limiting bosses matching the limiting grooves is provided on the outer peripheral edge of the upper surface of the orifice plate.
3. The packaging structure for a dual-labeling diagnostic reagent according to claim 2, characterized in that: The inner surface of the cover plate is also provided with a baffle assembly, which includes multiple rows of transverse baffles and multiple columns of longitudinal baffles. The transverse baffles and the longitudinal baffles are arranged in a cross-staggered manner, and when the cover plate is covered on the hole plate, the transverse baffles and the longitudinal baffles are interspersed in the intervals between the probe holes.
4. The packaging structure for a dual-labeling diagnostic reagent according to claim 3, characterized in that: The inner surface of the cover plate is vertically downwardly provided with a plurality of limit columns, and the limit columns are arranged at the intersection of the transverse baffle and the longitudinal baffle. The upper surface of the orifice plate is also provided with limit holes matching the limit columns, and the limit holes are located at the intervals between the probe holes.
5. The packaging structure for a dual-labeling diagnostic reagent according to claim 1, characterized in that: Card slots are provided on the outer side walls of the first reagent chamber, the second reagent chamber and the third reagent chamber, and snaps are also provided on the card slots. The box cover of the triple reagent kit is respectively provided with limit blocks of matching shape and position corresponding to the card slots of the first reagent chamber, the second reagent chamber and the third reagent chamber, and the limit blocks are provided with card holes matching the snaps.
6. The packaging structure for a dual-labeling diagnostic reagent according to claim 5, characterized in that: The second reagent chamber is staggered with the first reagent chamber and the third reagent chamber on the left and right sides, and the slots of the first reagent chamber and the third reagent chamber are located on the outer side wall on the left side thereof, and the slot of the second reagent chamber is located on the outer side wall on the right side thereof. The left side of the box cover is respectively provided with limit blocks of matching shape and position corresponding to the slots of the first reagent chamber and the third reagent chamber, and the right side of the box cover is also provided with limit blocks of matching shape and position corresponding to the slots of the second reagent chamber.
7. The packaging structure for a dual-labeling diagnostic reagent according to claim 1, characterized in that: The height of the bottle body of the dispensing tube is greater than the depth of the second receiving hole, and the height of the bottle body of the sealed penicillin bottle is greater than the depth of the third receiving hole.
8. The packaging structure for a dual-labeling diagnostic reagent according to claim 1, characterized in that: The outer packaging box is a transparent outer packaging box.
Citation Information
Patent Citations
Reagent kit for early diagnosis of recessive mastitis
CN201518023U
Combined parallel detection and diagnosis kit of leukemia-fused gene
CN203021568U
Homocysteine concentration detection kit
CN212134595U