Slide cleaning device
By designing a slide cleaning device that includes a flushing and leaching structure, the problem of low slide cleaning efficiency is solved, continuous operation of the slide during the cleaning process is achieved, and experimental efficiency and accuracy are improved.
Patent Information
- Application Number
- CN202422535939.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-10-18
- Publication Date
- 2025-09-16
- Estimated Expiration
- 2034-10-18
AI Technical Summary
The slide cleaning process is time-consuming and labor-intensive, and the cleaning efficiency is low, especially when a large number of slides need to be processed in brain science experiments.
A glass slide cleaning device is designed, which includes a rinsing structure and an extraction structure. By providing a first and a second container and a matching glass slide rack, the glass slide does not need to be removed from the rack during the entire cleaning process and can be directly transferred from the rinsing structure to the extraction structure, thereby realizing the continuous operation of rinsing, drying, extraction and re-drying.
It improves the efficiency of slide cleaning, ensures the consistency of rinsing and extraction quantities, reduces manual operations, and improves the efficiency and accuracy of experiments.
Smart Images
Figure CN223337900U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of experimental instruments, in particular to a slide cleaning device. Background Art
[0002] Currently, brain science experiments require a large number of slides. A complete dissection of a mouse brain might require 200 slides. To ensure smooth experimental progress, around 2,000 slides are typically washed at once. Newly purchased slides undergo special processing before use, including rinsing with running purified water, drying in an oven, and then leaching with a solution of gelatin and potassium chromium sulfate dodecahydrate in a specific ratio. After leaching, the slides are then dried again.
[0003] In the above process, the experimenters need to place the glass slides in a plastic box and then rinse them with pure water. After rinsing and drying, the glass slides in the plastic box need to be transferred one by one to the glass slide rack. The glass slide rack is then placed in the gelatin solution for immersion. The glass slide rack can generally only hold 30 glass slides at a time, and multiple immersions are required, which makes the whole process time-consuming and labor-intensive, and the cleaning efficiency is low. Utility Model Content
[0004] The main purpose of the utility model is to provide a glass slide cleaning device, aiming to solve the problem of low efficiency in current glass slide cleaning.
[0005] To achieve the above-mentioned purpose, the present invention provides a slide cleaning device, comprising:
[0006] The flushing structure includes a first container and a flushing pipe, wherein the first container has an opening for flushing the slide, and the flushing pipe is connected to the first container and is used to connect the first container to an external flushing device;
[0007] an extraction structure comprising a second container spaced apart from the first container, the second container having an opening and containing an extraction liquid; and
[0008] The slide rack is used to place slides, and the slide rack can be placed in the first container or the second container.
[0009] In one embodiment, the first container is provided with a plurality of water inlets;
[0010] The flushing pipeline includes a first pipeline and multiple second pipelines, the first pipeline is used to communicate with an external flushing device, and one end of the multiple second pipelines is connected to the first pipeline, and the other end is respectively connected to the multiple water inlets.
[0011] In one embodiment, the diameter of the first pipe is larger than the diameter of the second pipe.
[0012] In one embodiment, a first water outlet pipe is further provided at the bottom of the first container.
[0013] In one embodiment, a second water outlet pipe is provided at the bottom of the second container, and a valve is provided on the second water outlet pipe.
[0014] In one embodiment, the slide rack has a plurality of accommodating layers spaced apart in a vertical direction, and each of the accommodating layers is provided with a plurality of mounting grooves for placing slides.
[0015] In one embodiment, the first container is provided with a plurality of water inlets for communicating with an external flushing device;
[0016] The plurality of water inlets are spaced apart in the vertical direction, so that when the slide rack is placed in the first container, each of the accommodating layers corresponds to at least one water inlet in the horizontal direction.
[0017] In one embodiment, the slide rack further includes a plurality of stop bars, each of which is disposed around a side end of each of the accommodating layers and is used to abut against a side end of the slide.
[0018] In one embodiment, the slide rack is further provided with a handle.
[0019] In one embodiment, the slide cleaning device further includes a foot, and the foot includes:
[0020] a plurality of support rods, each end of the support rod being connected to the bottom of the first container or the bottom of the second container; and
[0021] The supporting plate is arranged below the first container and the second container, and is used to be connected to the other end of each of the supporting rods.
[0022] The technical solution of the present invention provides a rinsing structure for rinsing glass slides, and an extraction structure for extracting the rinsed and dried glass slides. The first container and the second container are spaced apart, and a slide rack capable of being placed in the first container or the second container is further provided, so that the slides can be directly transferred from the first container to the second container via the slide rack. By integrating the rinsing structure and the extraction structure and providing a slide rack as a companion, the present solution allows the slides to be rinsed, dried, extracted, and then dried again without having to be removed from the slide rack. This ensures that the number of slides rinsed and extracted is consistent, thereby improving the cleaning efficiency of the slides. BRIEF DESCRIPTION OF THE DRAWINGS
[0023] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the following briefly introduces the drawings required for use in the embodiments or the description of the prior art. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on the structures shown in these drawings without paying any creative work.
[0024] Figure 1 This is a structural diagram of an embodiment of a slide cleaning device provided by the present invention;
[0025] Figure 2 for Figure 1 Structural diagram of the middle flushing structure;
[0026] Figure 3 for Figure 1 Schematic diagram of the structure of the medium slide rack.
[0027] Description of Figure Numbers:
[0028] 1000. Slide cleaning device; 1. Flushing structure; 11. First container; 111. Water inlet; 112. First water outlet pipe; 12. Flushing pipe; 121. First pipe; 122. Second pipe; 2. Extraction structure; 21. Second container; 211. Second water outlet pipe; 212. Valve; 3. Slide rack; 31. Accommodating layer; 311. Mounting groove; 312. Stop bar; 32. Handle; 4. Footrest; 41. Support rod; 42. Loading plate.
[0029] The realization of the purpose, functional features and advantages of the present invention will be further explained in conjunction with embodiments and with reference to the accompanying drawings. DETAILED DESCRIPTION
[0030] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts shall fall within the scope of protection of the present invention.
[0031] It should be noted that if the embodiments of the present invention involve directional indications (such as up, down, left, right, front, back, etc.), the directional indications are only used to explain the relative position relationship, movement status, etc. between the components in a certain specific posture. If the specific posture changes, the directional indications will also change accordingly.
[0032] In addition, if there are descriptions involving "first", "second", etc. in the embodiments of the present invention, the descriptions of "first", "second", etc. are only for descriptive purposes and cannot be understood as indicating or implying their relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features limited to "first" and "second" may explicitly or implicitly include at least one of such features. In addition, if "and / or" or "and / or" appears in the full text, its meaning includes three parallel schemes. Taking "A and / or B" as an example, it includes scheme A, or scheme B, or a scheme in which A and B are satisfied at the same time. In addition, the technical solutions between the various embodiments can be combined with each other, but it must be based on the ability of ordinary technicians in this field to implement. When the combination of technical solutions is mutually contradictory or cannot be implemented, it should be deemed that such a combination of technical solutions does not exist and is not within the scope of protection required by the present invention.
[0033] Currently, brain science experiments require a large number of slides. A complete dissection of a mouse brain might require 200 slides. To ensure smooth experimental progress, around 2,000 slides are typically washed at once. Newly purchased slides undergo special processing before use, including rinsing with running purified water, drying in an oven, and then leaching with a solution of gelatin and potassium chromium sulfate dodecahydrate in a specific ratio. After leaching, the slides are then dried again.
[0034] In the above process, the experimenters need to place the glass slides in a plastic box and then rinse them with pure water. After rinsing and drying, the glass slides in the plastic box need to be transferred one by one to the glass slide rack. The glass slide rack is then placed in the gelatin solution for immersion. The glass slide rack can generally only hold 30 glass slides at a time, and multiple immersions are required, which makes the whole process time-consuming and labor-intensive, and the cleaning efficiency is low.
[0035] The main purpose of the utility model is to provide a glass slide cleaning device, aiming to solve the problem of low efficiency in current glass slide cleaning.
[0036] See also Figure 1 The present invention proposes a glass slide cleaning device 1000, including a flushing structure 1, an leaching structure 2 and a glass slide rack 3. The flushing structure 1 includes a first container 11 and a flushing pipe 12. The first container 11 has an opening for rinsing glass slides. The flushing pipe 12 is connected to the first container 11 and is used to connect the first container 11 with an external flushing device; the leaching structure 2 includes a second container 21 spaced apart from the first container 11, the second container 21 has an opening and is filled with leaching liquid; the glass slide rack 3 is used to place glass slides, and the glass slide rack 3 can be placed in the first container 11 or the second container 21.
[0037] The technical solution of the present invention provides the rinsing structure 1 for rinsing glass slides, and the leaching structure 2 for leaching the rinsed and dried glass slides. The first container 11 and the second container 21 are spaced apart, and a slide rack 3 capable of being placed in either the first container 11 or the second container 21 is further provided, so that the slides can be directly transferred from the first container 11 to the second container 21 via the slide rack 3. By integrating the rinsing structure 1 and the leaching structure 2 and providing the slide rack 3 in conjunction with them, the present solution allows the slides to be rinsed, dried, leached, and then dried again without having to be removed from the slide rack 3. This ensures that the number of slides rinsed and leached is consistent, thereby improving the cleaning efficiency of the slides.
[0038] It should be noted that during the cleaning process of the slide, the main function of the leaching is to remove various contaminants attached to the slide, including cell debris, residual biomolecules (such as proteins and nucleic acids), organic matter, inorganic salts, etc. This process helps to ensure the cleanliness of the slide, thereby improving the accuracy and reliability of subsequent experiments. In this embodiment, the leaching liquid is an aqueous solution prepared in a certain proportion of gelatin and potassium chromium sulfate dodecahydrate. Of course, corresponding substances such as proteases and lysates can also be added. This solution does not limit the specific composition of the leaching liquid.
[0039] For further information, please refer to Figure 2 The first container 11 is provided with a plurality of water inlets 111. The flushing pipe 12 includes a first pipe 121 and a plurality of second pipes 122. The first pipe 121 is used to communicate with an external flushing device. The plurality of second pipes 122 are connected to the first pipe 121 at one end and to the plurality of water inlets 111 at the other end. By providing multiple water inlets 111, the flushing liquid can be sprayed into the first container 11 from multiple different locations, thereby performing multi-directional flushing of the glass slides in the first container 11 and enhancing the flushing effect. The provision of the first pipe 121 and the second pipe 122 allows the flushing liquid in the external flushing device to be docked and distributed, providing a structural basis for the subsequent control of the flushing liquid flow rate in the water inlet 111.
[0040] It should be noted that this solution does not limit the specific number and arrangement of the water outlet and the second pipe 122. In one embodiment, please refer to Figure 2, there are six water inlets 111, which are distributed in groups of three on both sides of the first container 11. The water inlets 111 of the same group are on the same vertical line, and the water inlets 111 of different groups are arranged in a one-to-one correspondence on the same horizontal line. In this way, the flushing can be more uniform in the vertical direction and the structure of the pipeline is also simpler. In another embodiment, there are four water inlets 111, and they are all located on different vertical lines and horizontal planes. Such an arrangement enables the device to perform multi-directional flushing on the slides on the slide rack 3, increasing the flushing operation area and enhancing the flushing effect.
[0041] Furthermore, the diameter of the first pipe 121 is larger than the diameter of the second pipe 122. In this configuration, since the diameter of the second pipe 122 is smaller, the flow rate of the flushing liquid in the second pipe 122 can be increased by reducing the cross-section of the pipe under the condition of constant flow, further enhancing the flushing effect.
[0042] In order to discharge the flushing liquid in the first container 11, in one embodiment of the present invention, please refer to Figure 1 A first outlet pipe 112 is also provided at the bottom of the first container 11. This arrangement allows for smooth drainage of the rinsing liquid from the first container 11, ensuring a constant flow of the rinsing liquid and improving rinsing efficiency. It is worth noting that the first outlet pipe 112 is always open, and its diameter is significantly smaller than the outer diameter of the slide rack 3, ensuring stability of the slide rack 3.
[0043] In order to discharge the extract in the second container 21, in one embodiment of the present invention, please refer to Figure 1 A second water outlet pipe 211 is provided at the bottom of the second container 21, and a valve 212 is provided on the second water outlet pipe 211. It should be noted that, unlike the rinsing step, where the rinsing liquid needs to flow to improve the rinsing efficiency, in the leaching step, it is only necessary to ensure that the glass slide is immersed in the leaching liquid to achieve a good cleaning effect. In order to prevent the cleaning effect of the leaching liquid from falling to a low standard during the long-term leaching process, the second water outlet pipe 211 and the valve 212 are provided. When the leaching liquid needs to be replaced, the valve 212 is opened, and when the leaching liquid is completely filled, the valve 212 is closed, thereby achieving the renewal of the leaching liquid and ensuring the leaching effect.
[0044] In order to realize the installation of the slides on the slide rack 3, please refer to Figure 3The slide rack 3 has multiple vertically spaced storage layers 31, each of which is provided with multiple mounting slots 311 for receiving slides. The multiple storage layers 31 and mounting slots 311 allow slides to be installed in layers within the slide rack 3, resulting in a more rational arrangement and improved space utilization. This allows for the maximum possible storage of slides within a limited space, thereby enhancing cleaning efficiency.
[0045] Specifically, the slide rack 3 has a hollow structure, with gaps between each receiving layer 31, facilitating the flow of rinsing fluid and enhancing the rinsing effect. Furthermore, each receiving layer 31 includes two mounting plates spaced apart vertically. Opposing sides of the two mounting plates are provided with a plurality of corresponding mounting grooves 311. Each pair of corresponding mounting grooves 311 forms a mounting group, used to position a single slide. This arrangement, in which two corresponding mounting grooves 311 are provided to position a single slide, results in a simple structure and excellent positioning.
[0046] Furthermore, the first container 11 is provided with a plurality of water inlets 111 for communicating with external rinsing equipment. These inlets 111 are spaced apart vertically so that when the slide rack 3 is placed in the first container 11, each receiving layer 31 has at least one corresponding water inlet 111 in the horizontal direction. This arrangement ensures that, during the rinsing process, each slide on each receiving layer 31 is directly rinsed with the rinse liquid from the at least one water outlet, further improving the rinsing effect. It is understood that to ensure that all surfaces of the slides are thoroughly rinsed, multiple water inlets 111 can be provided on each receiving layer 31 at multiple locations corresponding to the first container 11, and multiple second pipes 122 can be provided accordingly.
[0047] Furthermore, the slide rack 3 includes a plurality of stop bars 312, each of which is disposed around the side ends of the receiving layers 31 and is configured to abut against the side ends of the slides. To ensure thorough rinsing, the flow rate of the rinse fluid is typically high and the rinse direction is varied. The stop bars 312 limit the horizontal position of the slides, preventing them from slipping during the cleaning process and improving the safety of the device.
[0048] It is worth mentioning that during the cleaning process, that is, between rinsing and drying, between drying and leaching, and between leaching and re-drying, the slide rack 3 needs to be transferred multiple times. To facilitate the removal and placement of the slide rack 3, the slide rack 3 is also provided with a handle 32. At the same time, to facilitate the removal and placement of slides, the respective receiving layers 31 are detachably connected. When slides need to be removed and placed, the slide rack 3 can be split into multiple receiving layers 31. When cleaning is required, the multiple receiving layers 31 with slides can be assembled into a slide rack 3, thereby improving the flexibility of the device.
[0049] In one embodiment of the present invention, please refer to Figure 1 The slide cleaning device 1000 further includes a footrest 4 comprising a plurality of support rods 41 and a support plate 42. The end of each support rod 41 is connected to the bottom of the first container 11 or the bottom of the second container 21. The support plate 42 is disposed below the first container 11 and the second container 21 and is connected to the other end of each support rod 41. The provision of the footrest 4 integrates the rinsing structure 1 and the leaching structure 2 into one, facilitating direct placement of the device on a test bench and improving its stability. The provision of the support rods 41 elevates the first container 11 and the second container 21, facilitating subsequent installation of the water outlet pipe.
[0050] The above description is merely an exemplary embodiment of the present invention and does not limit the patent scope of the present invention. All equivalent structural transformations made using the contents of the present invention specification and drawings under the technical concept of the present invention, or direct / indirect application in other related technical fields are included in the patent protection scope of the present invention.
Claims
1. A slide cleaning device, characterized in that: include: The flushing structure includes a first container and a flushing pipe, wherein the first container has an opening for flushing the slide, and the flushing pipe is connected to the first container and is used to connect the first container to an external flushing device; an extraction structure comprising a second container spaced apart from the first container, the second container having an opening and containing an extraction liquid; and The slide rack is used to place slides, and the slide rack can be placed in the first container or the second container.
2. The slide cleaning device according to claim 1, wherein: The first container is provided with a plurality of water inlets; The flushing pipeline includes a first pipeline and multiple second pipelines, the first pipeline is used to communicate with an external flushing device, and one end of the multiple second pipelines is connected to the first pipeline, and the other end is respectively connected to the multiple water inlets.
3. The slide cleaning device according to claim 2, wherein: The diameter of the first pipe is larger than the diameter of the second pipe.
4. The slide cleaning device according to claim 1, wherein: A first water outlet pipe is also provided at the bottom of the first container.
5. The slide cleaning device according to claim 1, wherein: A second water outlet pipe is provided at the bottom of the second container, and a valve is provided on the second water outlet pipe.
6. The slide cleaning device according to claim 1, wherein: The slide rack has a plurality of accommodating layers spaced apart in a vertical direction, and each of the accommodating layers is provided with a plurality of mounting grooves for placing slides.
7. The slide cleaning device according to claim 6, wherein: The first container is provided with a plurality of water inlets for communicating with an external flushing device; The plurality of water inlets are spaced apart in the vertical direction, so that when the slide rack is placed in the first container, each of the accommodating layers corresponds to at least one water inlet in the horizontal direction.
8. The slide cleaning device according to claim 6, wherein: The slide rack further comprises a plurality of stop bars, each of which is arranged around a side end of each of the accommodating layers and is used to abut against a side end of the slide.
9. The slide cleaning device according to claim 6, wherein: The slide rack is also provided with a handle.
10. The slide cleaning device according to claim 1, wherein: The slide cleaning device further includes a footrest, and the footrest includes: a plurality of support rods, each end of the support rod being connected to the bottom of the first container or the bottom of the second container; and The supporting plate is arranged below the first container and the second container, and is used to be connected to the other end of each of the supporting rods.